The meaning of the symbols of dreams/ seen in a dream.


Psoriasis

A condition characterised by the eruption of circumscribed discrete and confluent reddish, silvery scaled lesions... psoriasis

Pain

An unpleasant sensory or emotional experience that is derived from sensory stimuli and modified by individual memory, expectations and emotions.... pain

Palpitation

Forcible and/or irregular beating of the HEART such that the person becomes conscious of its action.

Causes As a rule, a person is not conscious of the beating of the heart except when the nervous system is unduly excited. A disorder of the rhythm of the heart (ARRHYTHMIA) may cause palpitations. Sudden emotions, such as fright, or overuse of tobacco, tea, co?ee or alcohol may bring it on. Sometimes it may appear in people with organic heart disease.

Symptoms There may simply be a ?uttering of the heart and a feeling of faintness, or the heart may be felt pounding and the arteries throbbing, causing great distress. The subject may be conscious of the heart missing beats.

Treatment Although these symptoms can be unpleasant, they do not necessarily signify serious disease. Moderate exercise is a good thing. If the person is a smoker, he or she should stop. Tea, co?ee, alcohol or other stimulants should be taken sparingly. If symptoms persist or are severe, the individual should see a doctor and any underlying disorder should be investigated – including by exercise ECG – and treated. The BETA-ADRENOCEPTOR-BLOCKING DRUGS are the most useful drugs in controlling the palpitations of anxiety and those due to some cardiac arrhythmias.... palpitation

Pancreatitis

Inflammation of the pancreas... pancreatitis

Papilloma

Benign epithelial neoplasm in which neoplastic cells cover finger-like processes of dermis. Also anybenign epithelial neoplasm growing outward from an epithelial surface.... papilloma

Paraplegia

Stroke affecting one side... paraplegia

Pathology

Disease, particularly one with clear and obvious changes in structure or function; the study of same.... pathology

Pharyngitis

Inflammation of the mucous membrane and underlying part of the pharynx... pharyngitis

Placebo

Any dummy medical treatment or intervention. Originally, a medicinal preparation having no specific pharmacological activity against the person’s illness or complaint and given solely for the psychophysiological effects of the treatment. More recently, a dummy treatment administered to the control group in a controlled clinical trial in order that the specific and non-specific effects of the experimental treatment can be distinguished.... placebo

Pneumonia

Inflammation of lung tissue... pneumonia

Prevalence

The number of events, such as instances of a given disease, condition or other attribute, present at a particular time. Sometimes used to mean prevalence rate. When used without qualification, the term usually refers to the situation at a specified point in time (point prevalence). annual prevalence: The total number of persons with a given disease or attribute at any time during a year. lifetime prevalence: The total number of persons known to have had a given disease or attribute for at least part of their lives. period prevalence: The total number of persons known to have had a given disease or attribute at any time during a specified period. point prevalence: The total number of persons with a given disease or attribute at a specified point in time. See also “incidence”.... prevalence

Prurigo

An eruption of the skin causing severe itching... prurigo

Pruritus

Itching... pruritus

Pyelitis

An inflammation of the kidney pelvis, the interface between the urine-secreting inner surface of the kidney and the muscular ureter that drains into the bladder. It can be caused by kidney stones or an infection that has progressed up from the lower urinary tract. It alone is a serious condition...the next stage, pyelonephritis, since it involves the whole kidney, is still worse.... pyelitis

Pyrexia

A condition characterised by the presence of pus... pyrexia

Angina Pectoris

A painful chronic heart condition, characterized by an oppressive sensation, difficulty breathing, and pain in the chest or arms. Attacks are often triggered by exertion or a sudden adrenergic discharge, and the underlying cause is insufficient blood supply to the heart muscles... angina pectoris

Bubonic Plague

A severe illness caused by the Gram negative rod, Yersinia pestis. The reservoirs for the infection are various species of rodent and the bacteria are transmitted through the bite of the rat flea, Xenopsylla cheopis. Patients present with enlarged lymph glands (‘buboes’) often in the groin or armpit. Can become septicaemic or develop into a pneumo nia (‘Pneumonic Plague’) and spread by droplet. Also known in the past as “The Black Death”.... bubonic plague

Blood Pressure

Blood pressure is that pressure which must be applied to an artery in order to stop the pulse beyond the point of pressure. It may be roughly estimated by feeling the pulse at the wrist, or accurately measured using a SPHYGMOMANOMETER. It is dependent on the pumping force of the heart, together with the volume of blood, and on the elasticity of the blood vessels.

The blood pressure is biphasic, being greatest (systolic pressure) at each heartbeat and falling (diastolic pressure) between beats. The average systolic pressure is around 100 mm Hg in children and 120 mm Hg in young adults, generally rising with age as the arteries get thicker and harder. Diastolic pressure in a healthy young adult is about 80 mm Hg, and a rise in diastolic pressure is often a surer indicator of HYPERTENSION than is a rise in systolic pressure; the latter is more sensitive to changes of body position and emotional mood. Hypertension has various causes, the most important of which are kidney disease (see KIDNEYS, DISEASES OF), genetic predisposition and, to some extent, mental stress. Systolic pressure may well be over 200 mm Hg. Abnormal hypertension is often accompanied by arterial disease (see ARTERIES, DISEASES OF) with an increased risk of STROKE, heart attack and heart failure (see HEART, DISEASES OF). Various ANTIHYPERTENSIVE DRUGS are available; these should be carefully evaluated, considering the patient’s full clinical history, before use.

HYPOTENSION may result from super?cial vasodilation (for example, after a bath, in fevers or as a side-e?ect of medication, particularly that prescribed for high blood pressure) and occur in weakening diseases or heart failure. The blood pressure generally falls on standing, leading to temporary postural hypotension – a particular danger in elderly people.... blood pressure

Food Poisoning

This illness is characterised by vomiting, diarrhoea and abdominal pain, and results from eating food contaminated with metallic or chemical poisons, certain micro-organisms or microbial products. Alternatively, the foods – such as undercooked red kidney beans or ?sh of the scombroid family (mackerel and tuna) – may contain natural posions. Food poisoning caused by chemical or metallic substances usually occurs rapidly, within minutes or a few hours of eating. Among micro-organisms, bacteria are the leading cause of food poisoning, particularly Staphylococcus aureus, Clostridium perfringens (formerly Cl. welchii), Salmonella spp., Campylobacter jejuni, and Escherichia coli O157.

Staphylococcal food poisoning occurs after food such as meat products, cold meats, milk, custard and egg products becomes contaminated before or after cooking, usually through incorrect handling by humans who carry S. aureus. The bacteria produce an ENTEROTOXIN which causes the symptoms of food poisoning 1–8 hours after ingestion. The toxin can withstand heat; thus, subsequent cooking of contaminated food will not prevent illness.

Heat-resistant strains of Cl. perfringens cause food poisoning associated with meat dishes, soups or gravy when dishes cooked in bulk are left unrefrigerated for long periods before consumption. The bacteria are anaerobes (see ANAEROBE) and form spores; the anaerobic conditions in these cooked foods allow the germinated spores to multiply rapidly during cooling, resulting in heavy contamination. Once ingested the bacteria produce enterotoxin in the intestine, causing symptoms within 8–24 hours.

Many di?erent types of Salmonella (about 2,000) cause food poisoning or ENTERITIS, from eight hours to three days after ingestion of food in which they have multiplied. S. brendeny, S. enteritidis, S. heidelberg, S. newport and S. thompson are among those commonly causing enteritis. Salmonella infections are common in domesticated animals such as cows, pigs and poultry whose meat and milk may be infected, although the animals may show no symptoms. Duck eggs may harbour Salmonella (usually S. typhimurium), arising from surface contamination with the bird’s faeces, and foods containing uncooked or lightly cooked hen’s eggs, such as mayonnaise, have been associated with enteritis. The incidence of human S. enteritidis infection has been increasing, by more than 15-fold in England and Wales annually, from around 1,100 a year in the early 1980s to more than 32,000 at the end of the 1990s, but has since fallen to about 10,000. A serious source of infection seems to be poultry meat and hen’s eggs.

Although Salmonella are mostly killed by heating at 60 °C for 15 minutes, contaminated food requires considerably longer cooking and, if frozen, must be completely thawed beforehand, to allow even cooking at a su?cient temperature.

Enteritis caused by Campylobacter jejuni is usually self-limiting, lasting 1–3 days. Since reporting of the disease began in 1977, in England and Wales its incidence has increased from around 1,400 cases initially to nearly 13,000 in 1982 and to over 42,000 in 2004. Outbreaks have been associated with unpasteurised milk: the main source seems to be infected poultry.

ESCHERICHIA COLI O157 was ?rst identi?ed as a cause of food poisoning in the early 1980s, but its incidence has increased sharply since, with more than 1,000 cases annually in the United Kingdom in the late 1990s. The illness can be severe, with bloody diarrhoea and life-threatening renal complications. The reservoir for this pathogen is thought to be cattle, and transmission results from consumption of raw or undercooked meat products and raw dairy products. Cross-infection of cooked meat by raw meat is a common cause of outbreaks of Escherichia coli O157 food poisoning. Water and other foods can be contaminated by manure from cattle, and person-to-person spread can occur, especially in children.

Food poisoning associated with fried or boiled rice is caused by Bacillus cereus, whose heat-resistant spores survive cooking. An enterotoxin is responsible for the symptoms, which occur 2–8 hours after ingestion and resolve after 8–24 hours.

Viruses are emerging as an increasing cause of some outbreaks of food poisoning from shell?sh (cockles, mussels and oysters).

The incidence of food poisoning in the UK rose from under 60,000 cases in 1991 to nearly 79,000 in 2004. Public health measures to control this rise include agricultural aspects of food production, implementing standards of hygiene in abattoirs, and regulating the environment and process of industrial food production, handling, transportation and storage.... food poisoning

Panacea

Panacea is a term applied to a remedy for all diseases, or more usually to a remedy which bene?ts many di?erent diseases.... panacea

Pandemic

A widespread epidemic which may affect large areas of the world.... pandemic

Pancreas

This is a gland situated above the navel in the abdominal cavity that extends from the left side to the center, with its head tucked into the curve of the duodenum. It is 6-8 inches long, weighs 3 or 4 ounces, secretes pancreatic enzymes and alkali into the duodenum in concert with the gallbladder and liver, and secretes the hormones insulin and glucagon into the blood. Insulin acts to facilitate the absorption of blood glucose into fuel-needing cells, and glucagon stimulates a slow release of glucose from the liver, primarily to supply fuel to the brain. That most cherished organ uses one-quarter of the sugar in the blood and has no fuel storage. Pancreatic enzymes are basically those that digest fats, carbohydrates and proteins into their smaller components of fatty acids+glycerol, maltose, and amino acids...as well as curdling milk (thought you might want to know).... pancreas

Paralysis

Paralysis, or PALSY, is loss of muscular power due to some disorder of the NERVOUS SYSTEM. Weakness – rather than total movement loss – is sometimes described as paresis. Paralysis may be temporary or permanent and may be accompanied by loss of feeling.

Paralysis due to brain disease The most common form is unilateral palsy, or HEMIPLEGIA, generally arising from cerebral HAEMORRHAGE, THROMBOSIS or EMBOLISM affecting the opposite side of the BRAIN. If all four limbs and trunk are affected, the paralysis is called quadraplegia; if both legs and part of the trunk are affected, it is called paraplegia. Paralysis may also be divided into ?accid (?oppy limbs) or spastic (rigid).

In hemiplegia the cause may be an abscess, haemorrhage, thrombosis or TUMOUR in the brain. CEREBRAL PALSY or ENCEPHALITIS are other possible causes. Sometimes damage occurs in the parts of the nervous system responsible for the ?ne control of muscle movements: the cerebellum and basal ganglion are such areas, and lack of DOPAMINE in the latter causes PARKINSONISM.

Damage or injury Damage to or pressure on the SPINAL CORD may paralyse muscles supplied by nerves below the site of damage. A fractured spine or pressure from a tumour may have this e?ect. Disorders affecting the cord which can cause paralysis include osteoarthritis of the cervical vertebrae (see BONE, DISORDERS OF), MULTIPLE SCLEROSIS (MS), MYELITIS, POLIOMYELITIS and MENINGITIS. Vitamin B12 de?ciency (see APPENDIX 5: VITAMINS) may also cause deterioration in the spinal cord (see also SPINE AND SPINAL CORD, DISEASES AND INJURIES OF).

Neuropathies are a group of disorders, some inherited, that damage the peripheral nerves, thus affecting their ability to conduct electrical impulses. This, in turn, causes muscle weakness or paralysis. Among the causes of neuropathies are cancers, DIABETES MELLITUS, liver disease, and the toxic consequences of some drugs or metals – lead being one example.

Disorders of the muscles themselves – for example, muscular dystrophy (see MUSCLES, DISORDERS OF – Myopathy) – can disturb their normal working and so cause partial or complete paralysis of the part(s) affected.

Treatment The aim of treatment should be to remedy the underlying cause – for example, surgical removal of a displaced intervertebral

disc or treating diabetes mellitus. Sometimes the cause cannot be recti?ed but, whether treatable or not, physiotherapy is essential to prevent joints from seizing up and to try to maintain some tone in muscles that may be only partly affected. With temporary paralysis, such as can occur after a STROKE, physiotherapy can retrain the sufferers to use their muscles and joints to ensure mobility during and after recovery. Patients with permanent hemiplegia, paraplegia or quadraplegia need highly skilled nursing care, rehabilitative support and resources, and expert help to allow them, if possible, to live at home.... paralysis

Paranoia

A condition whose main characteristic is the delusion (see DELUSIONS) that other people are (in an unclear way) connected to the affected individual. A sufferer from paranoia constructs a complex of beliefs based on his or her interpretation of chance remarks or events. Persecution, love, jealousy and self-grandeur are among the emotions evoked. Acute paranoia – a history of less than six months – may be the result of drastic changes in a person’s environment, such as war, imprisonment, famine or even leaving home for the ?rst time. Chronic paranoia may be caused by brain damage, substance abuse (including alcohol and cannbis), SCHIZOPHRENIA or severe DEPRESSION. Those affected may become constantly suspicious and angry and tend to live an isolated existence, exhibiting di?cult and odd behaviour. Often believing themselves to be normal, they do not seek treatment. If treated early with antipsychotic drugs, they often recover; if not, the delusions and accompanying erratic behaviour become entrenched. (See MENTAL ILLNESS.)... paranoia

Parasite

A plant or animal which lives upon or within or upon another living organism at whose expense it obtains some advantage without compensation. By convention, human parasitology covers the study of the protozoa, helminths and arthropods infecting humans.... parasite

Parity

Equality or comparability between two things. Parity legislation, usually applicable to mental health conditions like depression or schizophrenia, requires that health insurers adhere to a principle of equal treatment when making decisions regarding mental health benefits, comparable with medical benefits.... parity

Paronychia

The term applied to in?ammation near the nail (see under SKIN). The infection, usually caused by Staphyloccous aureus (see STAPHYLOCOCCUS), may affect the tissues around the nail, including its root, and sometimes spreads to the pulp of the affected ?nger or toe. The tendons that run along the back of the infected digit may occasionally become infected. Acute paronychia is the most common type, with local pain and tenderness and swelling of the nail fold. Treatment is with ANTIBIOTICS or, if an ABSCESS forms, local surgery to release any pus. Sometimes infection may be caused by a virus, against which antibiotics are ine?ective. If viral infection persists then antiviral drugs may eradicate it.

Chronic paronychia occurs with reinfection of the nail bed. This is usually because the person’s hands are regularly immersed in water, making the skin vulnerable to infection. The ?nger should be kept dry and a dry dressing applied accompanied by a course of antibiotics

– FLUCLOXACILLIN or a cephalosporin.... paronychia

Paroxysm

Cyclic manifestation of acute illness in malaria, characterised by a rise in temperature with accompanying symptoms, usually caused by invasion of the blood by a brood of parasites released from RBC’s.... paroxysm

Parsley

(American) Resembling the garnish Parslee, Parsleigh, Parsly, Parsli, Parslie, Parslea... parsley

Pathological

Indicative of, or caused by, a disease or condition.... pathological

Pectoral

Effective in diseases of the chest... pectoral

Pediculosis

A parasitic infestation of the head, the hairy parts of the body and the clothing by adult lice, larvae and nits (eggs), which often results in severe itching and excoriation of the scalp and body. Secondary infection can occur. Infesting agents include Pediculus capitis, the head louse, P. humanus, the body louse, and Pthirus pubis, the crab louse, which usually infest the pubic region, but may also infest the hair of the face, axillae and the bodysurfaces.... pediculosis

Pellagra

A syndrome resulting from niacin deficiency, associated with photosensitive dermatitis, mucous membrane inflammation, diarrhoea and psychiatric disturbances.... pellagra

Pemphigus

An acute or chronic disease of adults, with a singular or constant series of skin eruptions. The causes are not known, although both viruses and auto­immune reactions can be implicated. There are so many distinct types that it is probably not a distinct pathology but a symptom, like nausea, that occurs from many causes. Pemphigus of the mouth, lips and throat is rather common in the aged, particularly in those taking many management medications, and reduced to the spiritual poverty of “rest homes”. These need constant treatment (herbs work as well as medications), else the difficulty of eating, what with dry mouth, sore gums, gas and chronic constipation (from medications and adrenergic stress) coupled with SLBF (Soft Light Brown Food) and NOW the added insult of mouth sores can start the subtle downwards spiral of entropy and asthenia.... pemphigus

Peptic Ulcer

A stomach or duodenal ulcer, caused by excess or untimely secretions of gastric acid and pepsin, poor closure of the pyloric sphincter and digestive acid leakage into the duodenum, or poorly mucin-protected membranes resulting from infection or allergen irritation... peptic ulcer

Peri

A pre?x meaning around.... peri

Periwinkle

Catharanthus roseus

Apocynaceae

San: Nityakalyani;

Hin: Sadabahar, Baramassi;

Mal: Ushamalari, Nityakalyani

Tel: Billaganeru;

Tam: Sudukattu mallikai; Pun: Rattanjot;

Kan: Kasikanigale, Nitya Mallige

Importance: Periwinkle or Vinca is an erect handsome herbaceous perennial plant which is a chief source of patented cancer and hypotensive drugs. It is one of the very few medicinal plants which has a long history of uses as diuretic, antidysenteric, haemorrhagic and antiseptic. It is known for use in the treatment of diabetes in Jamaica and India. The alkaloids vinblastine and vincristine present in the leaves are recognized as anticancerous drugs. Vinblastine in the form of vinblastin sulphate is available in market under the trade name “VELBE” and Vincristine sulphate as “ONCOVIN” (Eli Lilly). Vinblastine is used in combination with other anticancer agents for the treatment of lymphocytic lymphoma, Hodgkin’s disease, testicular carcinoma and choriocarcinoma. Vincristine is used in acute leukemia, lymphosarcoma and Wilm’s tumour. Its roots are a major source of the alkaloids, raubasine (ajmalicine), reserpine and serpentine used in the preparation of antifibrillic and hypertension-relieving drugs. It is useful in the treatment of choriocarcinoma and Hodgkin’s disease-a cancer affecting lymph glands, spleen and liver. Its leaves are used for curing diabetes, menorrhagia and wasp stings. Root is tonic, stomachic, hypotensive, sedative and tranquilliser (Narayana and Dimri,1990).

Distribution: The plant is a native of Madagascar and hence the name Madagascar Periwinkle. It is distributed in West Indies, Mozambique, South Vi etnam, Sri Lanka , Philippines and Australia. It is well adapted to diverse agroclimatic situations prevalent in India and is commercially cultivated in the states of Tamil Nadu, Karnataka, Gujarat, Madhya Pradesh and Assam. USA, Hungary, West Germany, Italy, Netherlands and UK are the major consumers.

Botany: Catharanthus roseus (Linn.) G.Don.

syn. Vinca rosea Linn. belongs to the family Apocynaceae. It is an erect highly branched lactiferous perennial herb growing up to a height of one metre. Leaves are oblong or ovate, opposite, short-petioled, smooth with entire margin. Flowers are borne on axils in pairs. There are three flower colour types , pink, pink-eyed and white. Calyx with 5 sepal, green, linear, subulate. Corolla tube is cylindrical with 5 petals, rose-purple or white with rose-purple spot in the centre; throat of corolla tube hairy, forming a corona-like structure. The anthers are epipetalous borne on short filaments inside the bulging distal end of corolla tube converging conically above the stigma. Two characteristic secretary systems, namely a column like nectarium on both sides of pistil and a secretory cringulam circling the papillate stigma with a presumed role in pollination - fecundation process are present. Ovary bicarpellary, basally distinct with fused common style and stigma. The dehiscent fruit consists of a pair of follicles each measuring about 25 mm in length and 2.3 mm in diameter, containing up to thirty linearly arranged seeds with a thin black tegumen. On maturity, the follicles split along the length dehiscing the seeds.

Agrotechnology: Periwinkle grows well under tropical and subtropical climate. A well distributed rainfall of 1000 mm or more is ideal. In north India the low winter temperatures adversely affect the crop growth. It can grow on any type of soil ,except those which are highly saline, alkaline or waterlogged. Light soils, rich in humus are preferable for large scale cultivation since harvesting of the roots become easy.

Catharanthus is propagated by seeds. Fresh seeds should be used since they are short-viable. Seeds can be either sown directly in the field or in a nursery and then transplanted. Seed rate is 2.5 kg/ha for direct sowing and the seeds are drilled in rows 45 cm apart or broadcasted. For transplanted crop the seed rate is 500gm/ha. Seeds are sown in nursery and transplanted at 45x 30cm spacing after 60 days when the seedlings attain a height of 15-20cm Nursery is prepared two months in advance so that transplanting coincides with the on set of monsoons. Application of FYM at the rate of 15 t/ha is recommended. An alternate approach is to grow leguminous green manure crops and incorporate the same into the soil at flowering stage. Fertilisers are recommended at 80:40:40 kg N:P2O5:K2O/ha for irrigated crop and 60:30:30 kg/ha for rainfed crop. N is applied in three equal splits at planting and at 45 and 90 days after planting. 4 or 5 irrigations will be needed to optimise yield when rainfall is restricted. Fortnightly irrigations support good crop growth when the crop is grown exclusively as an irrigated crop. Weeding is carried out before each topdressing. Alternatively, use of fluchloraline at 0.75 kg a.i. /ha pre-plant or alachlor at 1.0 kg a.i. per ha as pre-emergence to weeds provides effective control of a wide range of weeds in periwinkle crop. Detopping of plants by 2cm at 50% flowering stage improves root yield and alkaloid contents. No major pests, other than Oleander hawk moth, have been reported in this crop. Fungal diseases like twig blight (top rot or dieback) caused by Phytophthora nicotianae., Pythium debaryanum, P. butleri and P. aphanidermatum; leaf spot due to Alternaria tenuissima, A. alternata, Rhizoctonia solani and Ophiobolus catharanthicola and foot-rot and wilt by Sclerotium rolfsii and Fusarium solani have been reported. However, the damage to the crop is not very serious. Three virus diseases causing different types of mosaic symptoms and a phyllody or little leaf disease due to mycoplasma -like organisms have also been reported; the spread of which could be checked by uprooting and destroying the affected plants.

The crop allows 3-4 clippings of foliage beginning from 6 months. The flowering stage is ideal for collection of roots with high alkaloid content. The crop is cut about 7 cm above the ground and dried for stem, leaf and seed. The field is irrigated, ploughed and roots are collected. The average yields of leaf, stem and root are 3.6, 1.5and 1.5 t/ha, respectively under irrigated conditions and 2.0, 1.0 and 0.75t/ha, respectively under rainfed conditions on air dry basis. The harvested stem and roots loose 80% and 70% of their weight, respectively. The crop comes up well as an undercrop in eucalyptus plantation in north India. In north western India a two year crop sequence of periwinkle-senna-mustard or periwinkle-senna- coriander are recommended for higher net returns and productivity (Krishnan,1995).

Properties and activity: More than 100 alkaloids and related compounds have so far been isolated and characterised from the plant. The alkaloid contents in different parts show large variations as roots 0.14-1.34%, stem 0.074-0.48%, leaves 0.32-1.16%, flowers 0.005-0.84%, fruits 0.40%, seeds 0.18% and pericarp 1.14% (Krishnan et al, 1983). These alkaloids includes monomeric indole alkaloids, 2-acyl indoles, oxindole, -methylene indolines, dihydroindoles, bisindole and others. Dry leaves contain vinblastine (vincaleucoblastine or VLB) 0.00013-0.00063%, and vincristine (leurocristine or LC) 0.0000003-0.0000153% which have anticancerous activity (Virmani et al, 1978). Other alkaloids reported are vincoside, isovincoside (strictosidine), catharanthine, vindolinine, lochrovicine, vincolidine, ajmalicine (raubasine), reserpine, serpentine, leurosine, lochnerine, tetrahydroalstonine, vindoline, pericalline, perivine, periformyline, perividine, carosine, leurosivine, leurosidine and rovidine. The different alkaloids possessed anticancerous, antidiabetic, diuretic, antihypertensive, antimicrobial, antidysenteric, haemorrhagic, antifibrillic, tonic, stomachic, sedative and tranquillising activities.... periwinkle

Pertussis

Whooping cough... pertussis

Petechiae

Pin point haemorrhages.... petechiae

Pharmacopoeia

An o?cial publication dealing with the recognised drugs and giving their doses, preparations, sources, and tests. Most countries have a pharmacopoeia of their own. That for Great Britain and Ireland is prepared by the British Pharmacopoeia Commission under the direction of the Medicines Commission. Many hospitals and medical schools have a small pharmacopoeia of their own, giving the prescriptions most commonly dispensed in that particular hospital or school. The British National Formulary is a compact authoritative volume for those concerned with the prescribing or dispensing of medicines.... pharmacopoeia

Pharmacy

1 The art or practice of preparing and preserving drugs, and of compounding and dispensing medicines according to the prescriptions of medical practitioners. 2 A place where drugs are dispensed.... pharmacy

Pharmacology

The branch of science that deals with the discovery and development of drugs. Those working in it (pharmacologists, doctors, scientists and laboratory technicians) determine the chemical structure and composition of drugs and how these act in the body. They assess the use of drugs in the prevention and treatment of diseases, their side-effects and likely toxicity. This work takes place in universities, hospitals and, in particular, the pharmaceutical industry. The latter has expanded tremendously during the 20th century and in Britain it is now one of the largest business sectors, not only providing the NHS with most of its pharmaceutical requirements but also exporting many medicines to other countries.

Pharmacologists not only research for new drugs, but also look for ways of synthesising them on a large scale. Most importantly, they organise with clinicians the thorough testing of drugs to ensure that these are safe to use, additionally helping to monitor the effects of drugs in regular use so as to identify unforeseen side-effects. Doctors and hospital pharmacists have a special reporting system (‘Yellow Cards’) under which they notify the government’s MEDICINES CONTROL AGENCY of any untoward consequences of drug treatments on their patients (see also MEDICINES).... pharmacology

Phlegm

Mucus in the throat or bronchi.... phlegm

Phobia

An irrational fear of particular objects or situations. A well-known American medical dictionary lists more than 200 ‘examples’ of phobias, ranging, alphabetically, from fear of air to fear of writing. Included in the list are phobophobia (fear of phobias) and triskaidekaphobia (fear of having 13 sitting at table).

Phobia is a form of obsession, and not uncommonly one of the features of anxiety. Treatment is behavioural therapy complemented in some patients with ANTIDEPRESSANT DRUGS. Care is needed, as some sufferers can become psychologically dependent on the drugs used to treat them (see DEPENDENCE). Those who suffer from what can be a most distressing condition can obtain help and advice from the Phobics Society. (See also MENTAL ILLNESS.)... phobia

Pilocarpine

A plant alkaloid and the primary bioactive substance reducible from Pilocarpus spp. (Jaborandi leaves). It is an almost pure parasympathomimetic (cholinergic), inducing lowered blood pressure and stimulating glandular secretions...EVERYWHERE. It stimulates sweating as well, a sympathetic cholinergic response. Anyway, it is used in eye drops these days to contract the pupil, lower ocular fluid pressure and take some of the stress off glaucoma. The refined alkaloid is better in the eyes, but the dried leaves are the usual complex agents of herb use and have some therapeutic values in low doses. Good Lobelia or Asclepias will work similarly and are both safer, fresher and more predictable as botanicals.... pilocarpine

Pleurisy

An inflammation of the serous membranes that both surround the lungs and line the inside of the chest cavity; the two membranes supply fluid lubrication between the expanding and contracting lungs and the body. Most pleurisy (and usually the milder form) follows or accompanies bronchitis or late winter chest colds...sort of pulmonary cabin fever. It may be dry pleurisy (with few secretions and sharp sticking pain that prevents any but moderate inhalation), or acute or effusive pleurisy (with fever, coughing, and built up serous fluids...usually tossed off as bronchitis). Some types are part of serious cardio-pulmonary disorders and/or chronic disease.... pleurisy

Pneumonitis

Inflammation of the lungs, from whatever cause. It may be concurrent with pneumonia or pleurisy...or the result of a defensive lineman knocking the air out of the quarterback...two days later.... pneumonitis

Poliomyelitis

An acute inflammation of the anterior horn cells of the spinal cord due to an enterovirus infection... poliomyelitis

Polyp

The immature life-cycle form of a jellyfish (or other cnidarian) which is attached to a substrate. Tumour projecting from mucosal surface.... polyp

Polypharmacy

1 The administration of many drugs at the same time. 2 The administration of an excessive number of drugs.... polypharmacy

Polyuria

Excess urination. The excreted wastes may stay unchanged but they are dissolved in a far higher volume of water. The causes range from diabetes, kidney disease, elevated thyroid function and the aftermath of diuretic-treated heart failure to booting a half keg of generic beer at a frat blowout... polyuria

Poultice

A soft mush prepared by various substances with oily or watery fluids... poultice

Praziquantel

A broad spectrum anthelmintic very effective against many human trematodiases (including all forms of schistosomiasis) and some cestode infections (e.g. hymenolepiasis; cysticercosis).... praziquantel

Preventive Medicine

The branch of medicine dealing with the prevention of disease and the maintenance of good health practices.... preventive medicine

Primary Care

Basic or general health care focused on the point at which a patient ideally first seeks assistance from the medical care system. It is the basis for referrals to secondary and tertiary level care.... primary care

Prognosis

An estimate of the outcome of a disease. Poor prognosis indicates that outcome is liable to be fatal.... prognosis

Prophylactic

Pertaining to the prevention of the development of a disease... prophylactic

Prostatitis

Inflammation of the prostate. The causes may be varied, ranging from infection to portal congestion to cancer to increased adipose estradiol release in the middle-aged male...to over-use.... prostatitis

Proteinuria

The presence of protein in the urine, sometimes a symptom of kidney compromise. See ALBUMINURIA... proteinuria

Protozoa

The lowest division of the animal kingdom, including unicellular or acellular organisms with a eukaryotic structure.... protozoa

Proximal

The area of the body that is closest to the heart.... proximal

Psyche

The mind or soul of an individual and his or her mental – in contrast to the physical – functioning.... psyche

Psychiatry

The branch of medicine that deals with the diagnosis, treatment and prevention of mental and emotional disorders. Those who specialize in care of older adults are called geriatric psychiatrists, old-age psychiatrists, psychogeriatricians or geropsychiatrists.... psychiatry

Psychology

Profession dealing with peoples’ behaviour and cognition and their effects.... psychology

Psychotherapy

Psychological (as opposed to physical) methods of treatment for mental disorders and psychological problems.... psychotherapy

Ptosis

See EYE, DISORDERS OF.... ptosis

Pulmonary

Relating to the LUNGS.... pulmonary

Purgative

Strong laxative... purgative

Pyorrhoea

A discharge of pus... pyorrhoea

Secondary Prevention

Measures that identify and treat asymptomatic persons who have already developed risk factors or preclinical disease, but in whom the condition is not clinically apparent. These activities are focused on early case-finding of asymptomatic disease that occurs commonly and has significant risk for negative outcome without treatment.... secondary prevention

Atrial Natriuretic Peptide

The atria (see ATRIUM) of the heart contain peptides with potent diuretic and vasodilating properties. It has been known since 1980 that extracts of human atria have potent diuretic and natriuretic effects in animals (see DIURETICS). In 1984 three polypeptide species were isolated from human atria and were called alpha, beta and gamma human atrial natriuretic peptides. Plasma concentration of immunoreactive atrial natriuretic peptide can now be measured: the levels are low in healthy subjects and are increased in patients with congestive heart failure. Infusion of the peptides reduces blood pressure and causes a natriuresis and diuresis.... atrial natriuretic peptide

Blood-poisoning

See SEPTICAEMIA.... blood-poisoning

Choroid Plexus

An extensive web of blood vessels occurring in the ventricles of the BRAIN and producing the CEREBROSPINAL FLUID.... choroid plexus

Cor Pulmonale

Another name for pulmonary heart disease, which is characterised by hypertrophy and failure of the right VENTRICLE of the heart as a result of disease of the LUNGS or disorder of the pulmonary circulation.... cor pulmonale

Diastolic Pressure

The pressure exerted by the blood against the arterial wall during DIASTOLE. This is the lowest blood pressure in the cardiac cycle. A normal reading of diastolic pressure in a healthy adult at rest is 70 mm Hg. (See HEART.)... diastolic pressure

Cerebral Palsy

The term used to describe a group of conditions characterised by varying degrees of paralysis and originating in infancy or early childhood. In some 80 per cent of cases this takes the form of spastic paralysis (muscle sti?ness), hence the now obsolete lay description of sufferers as ‘spastics’. The incidence is believed to be around 2 or 2·5 per 1,000 of the childhood community. In the majority of cases the abnormality dates from well before birth: among the factors are some genetic malformation of the brain, a congenital defect of the brain, or some adverse e?ect on the fetal brain as by infection during pregnancy. Among the factors during birth that may be responsible is prolonged lack of oxygen such as can occur during a di?cult labour; this may be the cause in up to 15 per cent of cases. In some 10–15 per cent of cases the condition is acquired after birth, when it may be due to KERNICTERUS, infection of the brain, cerebral thrombosis or embolism, or trauma. Acute illness in infancy, such as meningitis, may result in cerebral palsy.

The disease manifests itself in many ways. It may not be ?nally diagnosed and characterised until the infant is two years old, but may be apparent much earlier – even soon after birth. The child may be spastic or ?accid, or the slow, writhing involuntary movements known as athetosis may be the predominant feature. These involuntary movements often disappear during sleep and may be controlled, or even abolished, in some cases by training the child to relax. The paralysis varies tremendously. It may involve the limbs on one side of the body (hemiplegia), both lower limbs (paraplegia), or all four limbs (DIPLEGIA and QUADRIPLEGIA). Learning disability (with an IQ under 70) is present in around 75 per cent of all children but children with diplegia or athetoid symptoms may have normal or even high intelligence. Associated problems may include hearing or visual disability, behavioural problems and epilepsy.

The outlook for life is good, only the more severely affected cases dying in infancy. Although there is no cure, much can be done to help these disabled children, particularly if the condition is detected at an early stage. Assistance is available from NHS developmental and assessment clinics, supervised by community paediatricians and involving a team approach from experts in education, physiotherapy, occupational therapy and speech training. In this way many of these handicapped children reach adulthood able to lead near-normal lives. Much help in dealing with these children can be obtained from SCOPE (formerly the Spastics Society), and Advice Service Capability Scotland (ASCS).... cerebral palsy

General Paralysis Of The Insane

An outdated term for the tertiary stage of SYPHILIS.... general paralysis of the insane

Growing Pains

Ill-de?ned discomfort and pains that occur in the limbs of some children. They occur mainly at night between the ages of 6–12 years. The cause is unknown, but the condition is not signi?cant and does not require treatment once other more important conditions have been ruled out.... growing pains

Health Promotion

Any combination of health education and related organizational, political and economic interventions designed to facilitate behavioural and environmental adaptations that will improve or protect health.... health promotion

Hydrogen Peroxide

A thick colourless liquid with the formula H2O2 (water is H2O, possessing only one oxygen atom in its molecule). Available in solution with water and as a cream, it is readily reduced to water – giving up oxygen in the process, which causes the characteristic frothing seen when used. H2O2 has antiseptic and deodorising properties; thus it is used as a mouthwash, to clean wounds and ulcers, and occasionally to disinfect body cavities at operation. It is also a bleach.... hydrogen peroxide

Incubation Period

The time interval between exposure to an infectious agent (eg, bite) and appearance of the first sign or symptom of the disease in question.... incubation period

Ectopic Pregnancy

An ectopic pregnancy most commonly develops in one of the FALLOPIAN TUBES. Occasionally it may occur in one of the OVARIES, and rarely in the uterine cervix or the abdominal cavity. Around one in 200 pregnant women have an ectopic gestation. As pregnancy proceeds, surrounding tissues may be damaged and, if serious bleeding happens, the woman may present as an ‘abdominal emergency’. A life-threatening condition, this needs urgent surgery. Most women recover satisfactorily and can have further pregnancies despite the removal of one Fallopian tube as a result of the ectopic gestation. Death is unusual. This disorder of pregnancy may occur because infection or a previous abdominal injury or operation may have damaged the normal descent of an ovum from the ovary to the womb. The ?rst symptoms usually appear during the ?rst two months of pregnancy, perhaps before the woman realises she is pregnant. Severe lower abdominal pain and vaginal bleeding are common presenting symptoms. Ultrasound can be used to diagnose the condition and laparoscopy can be used to remove the products of conception. (See PREGNANCY AND LABOUR.)... ectopic pregnancy

Mushroom Poisoning

See FUNGUS POISONING.... mushroom poisoning

Paediatrics

Paediatrics means the branch of medicine dealing with diseases of children (see also NEONATOLOGY).... paediatrics

Lead Poisoning

Lead and lead compounds are used in a variety of products including petrol additives (in the UK, lead-free petrol is now mandatory), piping (lead water pipes were once a common source of poisoning), weights, professional paints, dyes, ceramics, ammunition, homeopathic remedies, and ethnic cosmetic preparations. Lead compounds are toxic by ingestion, by inhalation and, rarely, by skin exposures. Metallic lead, if ingested, is absorbed if it remains in the gut. The absorption is greater in children, who may ingest lead from the paint on old cots

– although lead-containing paints are no longer used for items that children may be in contact with.

Acute poisonings are rare. Clinical features include metallic taste, abdominal pain, vomiting, diarrhoea, ANOREXIA, fatigue, muscle weakness and SHOCK. Neurological effects may include headache, drowsiness, CONVULSIONS and COMA. Inhalation results in severe respiratory-tract irritation and systemic symptoms as above.

Chronic poisonings cause gastrointestinal disturbances and constipation. Other effects are ANAEMIA, weakness, pallor, anorexia, insomnia, renal HYPERTENSION and mental fatigue. There may be a bluish ‘lead line’ on the gums, although this is rarely seen. Neuromuscular dysfunction may result in motor weakness and paralysis of the extensor muscles of the wrist and ankles. ENCEPHALOPATHY and nephropathy are severe effects. Chronic low-level exposures in children are linked with reduced intelligence and behavioural and learning disorders.

Treatment Management of patients who have been poisoned is supportive, with removal from source, gastric decontamination if required, and X-RAYS to monitor the passage of metallic lead through the gut if ingested. It is essential to ensure adequate hydration and renal function. Concentrations of lead in the blood should be monitored; where these are found to be toxic, chelation therapy should be started. Several CHELATING AGENTS are now available, such as DMSA (Meso-2,3dimercaptosuccinic acid), sodium calcium edetate (see EDTA) and PENICILLAMINE. (See also POISONS.)... lead poisoning

Lumbar Puncture

A procedure for removing CEREBROSPINAL FLUID (CSF) from the spinal canal in the LUMBAR region in order: (1) to diagnose disease of the nervous system; (2) to introduce medicaments – spinal anaesthetics or drugs. A hollow needle is inserted into the lower section of the space around the SPINAL CORD (see diagram) and the cerebrospinal ?uid withdrawn. The procedure should not be done too rapidly or the subject may develop a severe headache. Examination of the cerebrospinal ?uid helps in the diagnosis and investigation of disorders of the brain and spinal cord – for example, MENINGITIS and SUBARACHNOID HAEMORRHAGE. When using the procedure to inject drugs into the CSF, the operator must take care to inject only those agents speci?cally produced for CSF injection. Deaths have occurred because the wrong drug has been injected, and there have been demands for specialised equipment and strict procedures that will prevent such tragedies.... lumbar puncture

Pallor

Unusual paleness of the SKIN caused by a reduced ?ow of blood or a de?ciency in normal pigments. Pallor may be a sign of fright, SHOCK, ANAEMIA, or other diseases.... pallor

Palpation

Examination of the surface of the body and the size, shape, and movements of the internal organs, by laying the ?at of the hand upon the skin.... palpation

Palsy

Another name for PARALYSIS. CEREBRAL PALSY involves total or partial paralysis of a limb or limbs due to a perinatal or early infancy brain lesion.... palsy

Paclitaxel

A CYTOTOXIC drug of the taxane group (see TAXANES). Given by intravenous transfusion, it is used under specialist supervision for the treatment of ovarian cancer (usually following surgery – see OVARIES, DISEASES OF) with or without CISPLATIN. NATIONAL INSTITUTE FOR CLINICAL EXCELLENCE (NICE) guidance in 2001 also recommended that the drug could be used to treat advanced breast cancer (see BREASTS, DISEASES OF) where initial cytotoxic therapy had failed or could not be used. Its use as ?rst-line treatment is limited to clinical trials.

Side-effects of paclitaxel include hypersensitivity, MYELOSUPPRESSION, cardiac ARRHYTHMIA and peripheral NEUROPATHY. Only a minority of patients respond to the drug, but when it works the results are often long-lasting.... paclitaxel

Pancreatin

Pancreatin preparations (often in the form of a powder) contain the four powerful enzymes (see ENZYME), trypsin, chymotrypsin, lipase, and amylase, which continue the digestion of foods started in the stomach (see PANCREAS – Functions; DIGESTION). They are given by mouth for the relief of pancreatic de?ciency in conditions such as pancreatitis (see PANCREAS, DISORDERS OF) and CYSTIC FIBROSIS. Pancreatin is also used for the preparation of pre-digested, or so-called peptonised, foods, such as milk and some starchy foods.... pancreatin

Palate

The partition between the cavity of the mouth, below, and that of the nose, above. It consists of the hard palate towards the front, which is composed of a bony plate covered below by the mucous membrane of the mouth, above by that of the nose; and of the soft palate further back, in which a muscular layer, composed of nine small muscles, is similarly covered. The hard palate extends a little further back than the wisdom teeth, and is formed by the maxillary and palate bones. The soft palate is concave towards the mouth and convex towards the nose, and it ends behind in a free border, at the centre of which is the prolongation known as the uvula. When food or air is passing through the mouth, as in the acts of swallowing, coughing, or vomiting, the soft palate is drawn upwards so as to touch the back wall of the throat and shut o? the cavity of the nose. Movements of the soft palate, by changing the shape of the mouth and nose cavities, are important in the production of speech.... palate

Pantothenic Acid

This plays an important part in the transfer of acetyl groups in the body’s METABOLISM and is one of the essential constituents of the diet. The daily requirement is probably around 10 milligrams. It is widely distributed in food stu?s, both animal and vegetable; yeast, liver and egg-yolk are particularly rich sources. (See APPENDIX

5: VITAMINS.)... pantothenic acid

Papaya

See Lechosa.... papaya

Papilla

A small projection, such as those with which the corium of the skin is covered, and which project into the epidermis and make its union with the corium more intimate; or those covering the tongue and projecting from its surface.... papilla

Papilloedema

Swelling of the OPTIC DISC of the EYE, speci?cally due to raised intracranial pressure. It can be seen by examining the back of the eye using an OPHTHALMOSCOPE and is an important sign in managing the care of patients with intracerebral disease such as tumours or MENINGITIS.... papilloedema

Papule

Small (less than 5 mm) solid elevation of the skin or mucous membranes. A larger lesion is called a nodule.... papule

Para

A pre?x meaning near, aside from, or beyond.... para

Paracentesis

The puncture by hollow needle or TROCAR and CANNULA of any body cavity (e.g. abdominal, pleural, pericardial), for tapping or aspirating ?uid. (See ASPIRATION.)... paracentesis

Paracetamol

(US, acetaminophen.) A non-opioid analgesic (see ANALGESICS) similar in e?cacy to aspirin, but without any demonstrable antiin?ammatory activity. It also has the advantage over aspirin of causing less gastric irritation. It is indicated for mild to moderate pain and pyrexia in a dose of 0.5–1g by mouth (maximum 4 doses every 24 hours).... paracetamol

Paraesthesia

A term applied to unusual feelings, apart from mere increase, or loss, of sensation, experienced by a patient without any external cause: for example, hot ?ushes, numbness, tingling, itching. Various paraesthesiae form a common symptom in some nervous diseases.... paraesthesia

Paraparesis

A disorder or injury of the NERVOUS SYSTEM in which the affected individual suffers from weakness in both legs and sometimes of the muscles in the lower trunk.... paraparesis

Paraphimosis

The constriction of the PENIS behind the glans by an abnormally tight foreskin that has been retracted. The condition causes swelling and severe pain. Sometimes the foreskin can be returned by manual manipulation after an ice pack has been applied to the glans or a topical local anaesthetic applied. Sometimes an operation to cut the foreskin is required.... paraphimosis

Parapsychology

The branch of PSYCHOLOGY that studies extrasensory perception. This includes precognition (seeing into the future); psychokinesis (a supposed ability of some people to move or change the state of objects by thinking); telepathy (communicating thoughts from one person to another); and clairvoyance (the ability to visualise events at a distance). These phenomena have no scienti?c explanation and some of these ‘abilities’ may be manifestations of mental illness such as SCHIZOPHRENIA.... parapsychology

Paraquat

A contact herbicide widely used in agriculture and horticulture. People using paraquat should be careful to protect their eyes and skin so as not to come into contact with it: a mouthful is enough to kill, and the substance is involved in around 40 suicides annually in the UK. Its major misuse has resulted from its being decanted from the professional pack into soft-drink bottles and kept in the kitchen. Medical assistance should be obtained as soon as possible, as some victims of poisoning may require hospital inpatient care, including renal DIALYSIS. Several medical centres have been set up throughout the country to provide treatment in cases of paraquat poisoning. Details of these can be obtained from the National Poisons Information Service.... paraquat

Parasiticide

A general term applied to agents or substances destructive to parasites (see PARASITE).... parasiticide

Parasympathomimetic

Mimicking major aspects of parasympathetic function. EXAMPLES: Amanita muscaria mushrooms, Pilocarpine, Lobelia.... parasympathomimetic

Parathion

One of the ORGANOPHOSPHORUS insecticides. It is highly toxic to humans and must therefore be handled with the utmost care.... parathion

Paresis

A state of partial PARALYSIS.... paresis

Parietal

The term applied to anything pertaining to the wall of a cavity: for example, parietal pleura, the part of the pleural membrane which lines the wall of the chest.... parietal

Parkinsonism

Parkinson’s disease characterised by rigidity of muscles and tremor of the hands... parkinsonism

Parotitis

In?ammation of the PAROTID GLAND caused by infection or by many AUTOIMMUNE DISORDERS. Epidemic parotitis is another name for MUMPS.... parotitis

Paroxetine

One of the ANTIDEPRESSANT DRUGS in the SELECTIVE SEROTONIN-REUPTAKE INHIBITORS (SSRIS) group. (See also MENTAL ILLNESS.)... paroxetine

Parturition

Labour – see PREGNANCY AND LABOUR.... parturition

Patch Test

This is used to identify possible substances that may be causing a patient’s ALLERGY. Small amounts of di?erent substances are placed on the skin – usually of the back or arm. If the patient is allergic then a red ?are and swelling will appear, usually within about 15 minutes. Sometimes the reaction may take longer – up to three days – to develop.... patch test

Patella

Also known as the knee-cap, this is a ?at bone shaped somewhat like an oyster-shell, lying in the tendon of the extensor muscle of the thigh, and protecting the knee-joint in front. (See also KNEE.)... patella

Patent Ductus Arteriosus

See DUCTUS ARTERIOSUS.... patent ductus arteriosus

Pathogen

An organism or substance which caused diseases.... pathogen

Pathogenic

This term means disease-producing, and is a term applied, for example, to bacteria capable of causing disease.... pathogenic

Pathognomonic

A term applied to signs or symptoms which are especially characteristic of certain diseases, and on the presence or absence of which the diagnosis depends. Thus the discovery of the Mycobacterium tuberculosis in the sputum is said to be pathognomonic of pulmonary tuberculosis.... pathognomonic

Peduncle

The stem or stalk of a single flower or a whole floral cluster.... peduncle

Peer Review

Review by individuals from the same discipline and with essentially equal qualifications (peers).... peer review

Pelvimetry

Measurement of the internal dimensions of the PELVIS. The four diameters measured are: transverse, anterioposterior, and left and right oblique. These measurements help to establish whether a fetus can be delivered normally. If the outlet is abnormally small, the mother will have to be delivered by CAESAREAN SECTION.... pelvimetry

Pemphigoid

See PEMPHIGUS.... pemphigoid

Pelvic Inflammatory Disease

(PID) Also called salpingitis, the term is applied to infections of the fallopian tubes that follow or are concurrent with uterine and cervical infections. Gonorrhea and Chlamydia are the most common organisms, and the infection is usually begun through sexual contact, although metabolic imbalances, subtler systemic infections like a slow virus, the local insult of herpes or candidiasis, the sequela of medication or recreational drugs, birth control pills, even an IUD...all can alter the vaginal flora and induce inflammation sufficient to allow an endogenous organism to start the infection. PID after birth, on the other hand, is usually the result of staph or strep infections infecting injured membranes.... pelvic inflammatory disease

Pelvis

The bony pelvis consists of the two hip bones, one on each side, with the sacrum and coccyx behind. It connects the lower limbs with the spine. In the female it is shallower than in the male and the ilia are more widely separated, giving great breadth to the hips of the woman; the inlet is more circular and the outlet larger; whilst the angle beneath the pubic bones (subpubic angle), which is an acute angle in the male, is obtuse in the female. All these points are of importance in connection with childbearing.

The contents of the pelvis are the urinary bladder and rectum in both sexes; in addition the male has the seminal vesicles and the prostate gland surrounding the neck of the bladder, whilst the female has the womb, ovaries, and their appendages.

A second meaning is as in renal pelvis – that part of the collecting system proximal to the URETER which collects urine from the renal pyramids (see KIDNEYS).... pelvis

Penicillamine

A metabolite of PENICILLIN which is one of the CHELATING AGENTS. It is sometimes used in RHEUMATOID ARTHRITIS that has not responded to the ?rst-line remedies and it is particularly useful when the disease is complicated by VASCULITIS. Penicillamine is also used as an antidote to poisoning by heavy metals, particularly copper and lead, as it is able to bind these metals and so remove their toxic effects. Because of its ability to bind copper it is also used in WILSON’S DISEASE where there is a de?ciency in the copper-binding protein so that copper is able to become deposited in the brain and liver, damaging these tissues.... penicillamine

Pentamidine

A drug that is used in the prevention and treatment of African trypanosomiasis (see SLEEPING SICKNESS), and in the treatment of LEISHMANIASIS.... pentamidine

Penis

The male organ through which the tubular URETHRA runs from the neck of the URINARY BLADDER to the exterior at the meatus or opening. URINE and SEMEN are discharged along the urethra, which is surrounded by three cylindrical bodies of erectile tissue, two of which (corpora cavernosa) lie adjacent to each other along the upper length of the penis and one (corpus spongiosum) lies beneath them. Normally the penis hangs down in a ?accid state in front of the SCROTUM. When a man is sexually aroused the erectile tissue, which is of spongy constituency and well supplied with small blood vessels, becomes engorged with blood.

This makes the penis erect and ready for insertion into the woman’s vagina in sexual intercourse. The end of the penis, the glans, is covered by a loose fold of skin – the foreskin or PREPUCE – which retracts when the organ is erect. The foreskin is sometimes removed for cultural or medical reasons.

A common congenital disorder of the penis is HYPOSPADIAS, in which the urethra opens somewhere along the under side; it can be repaired surgically. BALANITIS is in?ammation of the glans and foreskin. (See also REPRODUCTIVE SYSTEM; EJACULATION; IMPOTENCE; PRIAPISM.)... penis

Pennyroyal

Mentha pulegium. N.O. Labiateae.

Synonym: European Pennyroyal.

Habitat: Not common as a wild plant, except on damp heaths and commons. Frequently seen in cottage gardens. Indigenous to Britain and Europe.

Features ? This member of the mint family grows up to twelve inches high, the stem

being bluntly quadrangular. The one to one and a half inch long, egg-shaped leaves are opposite, on short stalks ; they are slightly serrate and nearly smooth. Purple flowers appear in August. The odour is rather pungent, mint-like but characteristic.

Part used ? The whole herb.

Action: Carminative, emmenagogue, diaphoretic and stimulant.

An infusion of 1 ounce to 1 pint of boiling water, taken warm in teacupful doses frequently repeated, is helpful in hysteria, flatulence and sickness. For children's ailments such as feverish colds, disordered stomach and measles, Pennyroyal infusion may be given in appropriate doses with confidence. Its diaphoretic and stimulant action recommends it for chills and incipient fevers, and the infusion works as an emmenagogue when such ailments retard and obstruct menstruation. The oil of Pennyroyal is a first-rate protection against the bites of mosquitoes, gnats, and similar winged pests. The herb is used to some extent as a flavouring. Although not so popular as other herbs for this purpose, the mint-like flavour and carminative virtues of Pennyroyal should recommend it to cooks as adding to both palatability and digestibility of various dishes.

American or Mock Pennyroyal are the names given to the dried leaves and flowering tops of Hedeoma pulegioides. This plant, although quite different in appearance from the European Pennyroyal, has similar medicinal values.... pennyroyal

Peony

Paeonia officinalis. N.O. Ranunculaceae.

Synonym: Common Peony, Piney.

Habitat: Cultivated in gardens.

Features ? Stem two feet high, thick, smooth, branched leaves, pinnate or lobed. Flowers (May) large, red, single, terminal. Transverse section of root is starchy, medullary rays tinged purple. Taste sweet, becoming bitter.

Part used ? Root.

Action: Tonic, antispasmodic.

Convulsive and spasmodic nervous troubles as chorea and epilepsy. Infusion of 1 ounce powdered root to 1 pint boiling water in wineglass

doses three or four times daily.... peony

Peptide

A compound formed by the union of two or more AMINO ACIDS.... peptide

Percussion

An aid to diagnosis practised by striking the patient’s body with the ?ngers, in such a way as to make it give out a note. It was introduced in 1761 by Leopold Auenbrugger (1722–1809) of Vienna, the son of an innkeeper, who derived the idea from the habit of his father tapping casks of wine to ascertain how much wine they contained. According to the degree of dullness or resonance of the note, an opinion can be formed as to the state of CONSOLIDATION of air-containing organs, the presence of abnormal cavities in organs, and the dimensions of solid and air-containing organs, which happen to lie next to one another. Still more valuable evidence is given by AUSCULTATION.... percussion

Percutaneous

Any method of administering remedies by passing them through the SKIN, as by rubbing in an ointment or applying a patch containing a drug.... percutaneous

Perforation

The perforation of one of the hollow organs of the abdomen or major blood vessels may occur spontaneously in the case of an ulcer or an advanced tumour, or may be secondary to trauma such as a knife wound or penetrating injury from a tra?c or industrial accident. Whatever the cause, perforation is a surgical emergency. The intestinal contents, which contain large numbers of bacteria, pass freely out into the abdominal cavity and cause a severe chemical or bacterial PERITONITIS. This is usually accompanied by severe abdominal pain, collapse or even death. There may also be evidence of free ?uid or gas within the abdominal cavity. Surgical intervention, to repair the leak and wash out the contamination, is often necessary. Perforation or rupture of major blood vessels, whether from disease or injury, is an acute emergency for which urgent surgical repair is usually necessary. Perforation of hollow structures elsewhere than in the abdomen – for example, the heart or oesophagus – may be caused by congenital weaknesses, disease or injury. Treatment is usually surgical but depends on the cause.... perforation

Pericarditis

Acute or chronic in?ammation of the PERICARDIUM, the membranous sac that surrounds the HEART. It may occur on its own or as part of PANCARDITIS, when in?ammation also affects the MYOCARDIUM and ENDOCARDIUM (membranous lining of the inside of the heart). Various causes include virus infection, cancer and URAEMIA. (See also HEART, DISEASES OF.)... pericarditis

Pericardium

The smooth membrane that surrounds the HEART.... pericardium

Perinatal

A term applied to the period starting a few weeks before birth, the birth itself and the week or two following it.... perinatal

Perineum

Popularly called the crotch, or crutch, this is the region situated between the opening of the bowel behind and of the genital organs in front. In women it becomes stretched in childbirth, and the vaginal opening may tear or need to be cut (see EPISIOTOMY) to facilitate delivery of the baby.... perineum

Periosteum

The membrane surrounding a BONE. The periosteum carries blood vessels and nerves for the nutrition and development of the bone. When it is irritated, an increased deposit of bone takes place beneath it; if it is destroyed, the bone may cease to grow and a portion may die and separate as a sequestrum.... periosteum

Periostitis

Periostitis means in?ammation on the surface of a BONE, affecting the PERIOSTEUM. (See BONE, DISORDERS OF.)... periostitis

Peripheral Nervous System

See NERVOUS SYSTEM.... peripheral nervous system

Peristalsis

The worm-like movement by which the stomach and bowels propel their contents. It consists of alternate waves of relaxation and contraction in successive parts of the intestinal tube. Any obstruction to the movement of the contents causes these contractions to become more forcible and are often accompanied by the severe form of pain known as COLIC.... peristalsis

Peritoneum

The serous membrane of the abdominal cavity. The parietal peritoneum lines the walls of the abdomen and the visceral peritoneum covers the abdominal organs. The two are continuous with one another at the back of the abdomen and form a complicated closed sac (see MESENTERY; OMENTUM). A small amount of ?uid is always present to lubricate the membrane, while a large amount collects in conditions associated with OEDEMA or in PERITONITIS.... peritoneum

Peritonsillar Abscess

The term applied to a collection of pus or an ABSCESS which occurs complicating an attack of TONSILLITIS. The collection of pus forms between the tonsil and the superior constrictor muscle of the pharynx. This condition is also known as quinsy; treatment drainage of the abscess and the administration of appropriate antibiotics.... peritonsillar abscess

Peritonitis

In?ammation of the PERITONEUM. It may be acute or chronic, localised or generally di?used, and its severity and danger may vary according to the cause.

Acute peritonitis generally arises because bacteria enter the peritoneal cavity, from penetrating wounds, e.g. stabs, from the exterior or from the abdominal organs. Hence conditions leading to perforation of the STOMACH, INTESTINE, BILE DUCT, URINARY BLADDER, and other hollow organs such as gastric ulcer (see STOMACH, DISEASES OF), typhoid fever (see ENTERIC FEVER), gall-stones (see under GALLBLADDER, DISEASES OF), rupture of the bladder, strangulated HERNIA, and obstructions of the bowels, may lead to peritonitis. Numerous bacteria may cause the in?ammation, most common being E. coli, streptococci and the gonococcus.

The symptoms usually begin with a RIGOR together with fever, vomiting, severe abdominal pain and tenderness. Shock develops and the abdominal wall becomes rigid. If untreated the patient usually dies. Urgent hospital admission is required. X-ray examination may show gas in the peritoneal cavity. Treatment consists of intravenous ?uids, antibiotics and surgical repair of the causative condition. Such treatment, together with strong analgesics is usually successful if started soon enough.... peritonitis

Permethrin

Along with phenothrin, this is a largely nontoxic pyrethroid insecticide, e?ective in SCABIES and lice infestations. Resistance may develop to these insecticides and also to MALATHION and CARBARYL, in which case topical treatment should be alternated among the di?erent varieties.... permethrin

Pernicious Anaemia

An autoimmune disease in which sensitised lymphocytes (see LYMPHOCYTE) destroy the parietal cells of the STOMACH. These cells normally produce intrinsic factor, which is the carrier protein for vitamin B12 that permits its absorption in the terminal ileum. Without intrinsic factor, vitamin B12 cannot be absorbed and this gives rise to a macrocytic ANAEMIA. The skin and mucosa become pale and the tongue smooth and atrophic. A peripheral NEUROPATHY is often present, causing paraesthesiae (see under TOUCH), numbness and even ATAXIA. The more severe neurological complication of sub-acute combined degeneration of the cord is fortunately more rare. The anaemia gets its name from the fact that before the discovery of vitamin B12 it was uniformly fatal. Now a monthly injection of vitamin B12 is all that is required to keep the patient healthy.... pernicious anaemia

Perphenazine

See PHENOTHIAZINES.... perphenazine

Petit Mal

An out-of-date term for less severe type of epileptic seizure (see EPILEPSY) that occurs usually in children or adolescents but less often in adults. The type of seizure is now referred to as an absence attack.... petit mal

Perspiration

Commonly called sweat, it is an excretion from the SKIN, produced by microscopic sweat-glands, of which there are around 2·5 million, scattered over the surface. There are two di?erent types of sweat-glands, known as eccrine and apocrine. Insensible (that is unnoticed) perspiration takes place constantly by evaporation from the openings of the sweat-glands, well over a litre a day being produced. Sensible perspiration (that is, obvious) – to which the term ‘sweat’ is usually con?ned – occurs with physical exertion and raised body temperature: up to 3 litres an hour may be produced for short periods. Normal sweating maintains the body within its customary temperature range and ensures that the skin is kept adequately hydrated – for example, properly hydrated skin of the palm helps the e?ectiveness of a person’s normal grip.

The chief object of perspiration is to maintain an even body temperature by regulating the heat lost from the body surface. Sweating is therefore increased by internally produced heat, such as muscular activity, or external heat. It is controlled by two types of nerves: vasomotor, which regulate the local blood ?ow, and secretory (part of the sympathetic nervous system) which directly in?uence secretion.

Eccrine sweat is a faintly acid, watery ?uid containing less than 2 per cent of solids. The eccrine sweat-glands in humans are situated in greatest numbers on the soles of the feet and palms of the hands, and with a magnifying glass their minute openings or pores can be seen in rows occupying the summit of each ridge in the skin. Perspiration is most abundant in these regions, although it also occurs all over the body.

Apocrine sweat-glands These start functioning at puberty and are found in the armpits, the eyelids, around the anus in association with the external genitalia, and in the areola and nipple of the breast. (The glands that produce wax in the ear are modi?ed apocrine glands.) The ?ow of apocrine sweat is evoked by emotional stimuli such as fear, anger, or sexual excitement.

Abnormalities of perspiration Decreased sweating may occur in the early stages of fever, in diabetes, and in some forms of glomerulonephritis (see KIDNEYS, DISEASES OF). Some people are unable to sweat copiously, and are prone to HEAT STROKE. EXCESSIVE SWEATING, OR HYPERIDROSIS, may be caused by fever, hyperthyroidism (see THYROID GLAND, DISEASES OF), obesity, diabetes mellitus, or an anxiety state. O?ensive perspiration, or bromidrosis, commonly occurs on the hands and feet or in the armpits, and is due to bacterial decomposition of skin secretions. A few people, however, sweat over their whole body surface. For most of those affected, it is the palmar and/or axillary hyperhidrosis that is the major problem.

Conventional treatment is with an ANTICHOLINERGIC drug. This blocks the action of ACETYLCHOLINE (a neurotransmitter secreted by nerve-cell endings) which relaxes some involuntary muscles and tightens others, controlling the action of sweat-glands. But patients often stop treatment because they get an uncomfortably dry mouth. Aluminium chloride hexahydrate is a topical treatment, but this can cause skin irritation and soreness. Such antiperspirants may help patients with moderate hyperhidrosis, but those severely affected may need either surgery or injections of BOTULINUM TOXIN to destroy the relevant sympathetic nerves to the zones of excessive sweating.... perspiration

Phaeochromocytoma

A disorder in which a vascular tumour of the adrenal medulla (see ADRENAL GLANDS) develops. The tumour may also affect the structurally similar tissues associated with the chain of sympathetic nerves. There is uncontrolled and irregular secretion of ADRENALINE and NORADRENALINE with the result that the patient suffers from episodes of high blood pressure (HYPERTENSION), raised heart rate, and headache. Surgery to remove the tumour may be possible; if not, drug treatment may help.... phaeochromocytoma

Phagocyte

Cells – including monocytes (a variety of LEUCOCYTES) in the blood and macrophages (see MACROPHAGE) in the tissues – that envelop and digest BACTERIA cells, cell debris and other small particles. Phagocytes are an essential part of the body’s defence mechanisms.... phagocyte

Phagocytosis

The act of absorbing and digesting fragments, detritus, or whole organisms, as an amoeba does. Granulocytes do this in the body.... phagocytosis

Phalanx

(Plural: phalanges.) The name given to any one of the small bones of the ?ngers and toes. The phalanges are 14 in number in each hand and foot – the thumb and great toe possessing only two each, whilst each of the other ?ngers and toes has three.... phalanx

Phallus

An alternative name for the PENIS, this word may also be used to describe a penis-like object. In embryology the phallus is the rudimentary penis before the urethral duct has completely developed.... phallus

Phantom Limb

Following the AMPUTATION of a limb, it is usual for the patient to experience sensations as if the limb were still present. This condition is referred to as a phantom limb. In most patients the sensation passes o? in time.... phantom limb

Pharmacokinetics

The way in which the body deals with a drug. This includes the drug’s absorption, distribution in the tissues, METABOLISM, and excretion.... pharmacokinetics

Pharynx

Another name for the throat. The term throat is popularly applied to the region about the front of the neck generally, but in its strict sense it means the irregular cavity into which the nose and mouth open above, from which the larynx and gullet open below, and in which the channel for the air and that for the food cross one another. In its upper part, the EUSTACHIAN TUBES open one on either side, and between them on the back wall grows a mass of glandular tissue – adenoids (see NOSE, DISORDERS OF).... pharynx

Phenelzine

An example of the widely used ANTIDEPRESSANT DRUGS which are classi?ed as MONOAMINE OXIDASE INHIBITORS (MAOIS). The drug is particularly useful because its stimulant e?ect is less than that of most other MAOIs.... phenelzine

Phenoxymethylpenicillin

See under PENICILLIN.... phenoxymethylpenicillin

Phenylketonuria

Commonly referred to as PKU, this is one of the less common, but very severe, forms of mental de?ciency. The incidence in populations of European origin is around 1 in 15,000 births. The condition is due to the inability of the baby to metabolise the amino acid, phenylalanine (see AMINO ACIDS). In the UK, every newborn baby is screened for PKU by testing a spot of their blood collected by the midwife. A positive diagnosis leads to lifelong treatment with a diet low in phenylalanine, with a good chance that the infant will grow up mentally normal. Parents of children with phenylketonuria can obtain help and information from the National Society for Phenylketonuria (UK) Ltd. (See also METABOLIC DISORDERS; GENETIC DISORDERS – Recessive genes.)... phenylketonuria

Phimosis

Tightness of the foreskin (PREPUCE) which prevents it from being pulled back over the underlying head (glans) of the PENIS. Some phimosis is normal in uncircumcised males until they are six months old. The condition may, however, persist, eventually causing problems with urination. BALANITIS may occur because the inside of the foreskin cannot be properly washed. There may be an increased risk of cancer of the penis. In adolescents and adults with phimosis, erection of the penis is painful. CIRCUMCISION is the treatment.... phimosis

Phlebitis

In?ammation of a vein. (See VEINS; VEINS, DISEASES OF.)... phlebitis

Phlebography

The study of the VEINS, particularly by means of X-rays after the veins have been injected with a radio-opaque substance.... phlebography

Phlebotomy

A traditional name for the operation of bloodletting by opening a vein. (See VEINS; VENESECTION.)... phlebotomy

Phocomelia

This is a great reduction in the size of the proximal parts of the limbs. In extreme cases the hands and feet may spring directly from the trunk. A rare condition, it occurred most commonly in children whose mothers took THALIDOMIDE in early pregnancy.... phocomelia

Pholcodine

An OPIOID cough suppressant similar to CODEINE; it is not, however, potent enough to suppress severe coughs and is also constipating.... pholcodine

Phosphaturia

The presence of excess phosphates in the urine. This occurs in...and can even cause, alkaline urine (it’s normally acidic), resulting in cloudy urine, small particle sedimentation, and the more common kinds of kidney stones.... phosphaturia

Phosphorus

A non-metallic element whose compounds are widely found in plant and animal tissues. In humans, this element is largely concentrated in BONE. Some phosphorus-containing compounds such as ADENOSINE TRIPHOSPHATE (ATP) and creatine phosphate are essential participants in the conversion and storage of energy that are part of the body’s METABOLISM. Pure phosphorus is toxic.... phosphorus

Photocoagulation

Coagulation of the tissues of the retina (see EYE) by laser, for treatment of diseases of the retina such as diabetic retinopathy (see under EYE, DISORDERS OF – Retina, disorders of).... photocoagulation

Photophobia

Sensitivity to light. It can occur in MIGRAINE, disorders of the eye, or in MENINGITIS.... photophobia

Photosensitivity

Abnormal reaction to sunlight. The condition usually occurs as a skin rash appearing in response to light falling on the skin, and it may be caused by substances that have been eaten or applied to the skin. These are called photosensitisers and may be dyes, chemicals in soaps, or drugs. Sometimes plants act as photosensitisers – for example, buttercups and mustard. The condition may occur in some illnesses such as lupus erythematosus (see under LUPUS).... photosensitivity

Physiology

Physiology is the branch of medical science that deals with the healthy functions of di?erent organs, and the changes that the whole body undergoes in the course of its activities. The teaching of physiology is a basic part of the medical student’s initial education.... physiology

Physiotherapy

An important treatment involving the use of physical measures, such as exercise, heat, manipulation and remedial exercises in the treatment of disease. An alternative name is PHYSICAL MEDICINE. It is an essential part of the rehabilitation of convalescent or disabled patients. Those who practise physiotherapy – physiotherapists – have a recognised training and, on successful completion of this, are placed on the profession’s o?cial register (see APPENDIX 8: PROFESSIONAL ORGANISATIONS.)... physiotherapy

Phytomenadione

The British Pharmacopoeia name for vitamin K. (See APPENDIX 5: VITAMINS.)... phytomenadione

Phytotherapy

Botanical or herbal medicine, often with a heavy emphasis on studies and monographs and their medical implications (with virtually none from North America), and with a philosophy of “little drug” medical uses and the reliance on the European phytopharmaceutical industry (where the studies came from). No judgment here; this approach is of great value to physicians, since it offers clear implications for medical use. This approach is, however, medical and mechanistic, not vitalist and wholistic... phytotherapy

Piles

See HAEMORRHOIDS.... piles

Pinna

The part of the EAR, formed of cartilage and skin, that is external to the head. In animals it is an important element in detecting the direction of sound.... pinna

Pins And Needles

A form of PARAESTHESIA, or disturbed sensation, such as may occur, for example, in NEURITIS or POLYNEURITIS.... pins and needles

Pinta

A nonvenereal tropical treponemal disease similar to yaws and caused by Treponema pertenue.... pinta

Piroxicam

An intermediate risk, oral non-steroidal antiin?ammatory drug (see NON-STEROIDAL ANTIINFLAMMATORY DRUGS (NSAIDS)) with prolonged action. Used to treat pain and in?ammation in RHEUMATOID ARTHRITIS, other musculoskeletal disorders, and acute GOUT.... piroxicam

Plantain

This English common name can refer to more than one species. For the banana-like plantain fruit, see Plátano; for the low-lying herb whose leaves are primarily used medicinally, see Llantén.... plantain

Pituitary Gland

Also known as the pituitary body and the hypophysis, this is an ovoid structure, weighing around 0·5 gram in the adult. It is attached to the base of the BRAIN, and lies in the depression in the base of the skull known as the sella turcica. The anterior part is called the adenohypophysis and the posterior part the neurohy-P pophysis. The gland is connected to the HYPOTHALAMUS of the brain by a stalk known as the hypophyseal or pituitary stalk.

The pituitary gland is the most important ductless, or endocrine, gland in the body. (See

ENDOCRINE GLANDS.) It exerts overall control of the endocrine system through the media of a series of hormones which it produces. The adenohypophysis produces trophic hormones (that is, they work by stimulating or inhibiting other endocrine glands) and have therefore been given names ending with ‘trophic’ or ‘trophin’. The thyrotrophic hormone, or thyroid-stimulating hormone (TSH), exerts a powerful in?uence over the activity of the THYROID GLAND. The ADRENOCORTICOTROPHIC HORMONE (ACTH) stimulates the cortex of the adrenal glands. GROWTH HORMONE, also known as somatotrophin (SMH), controls the growth of the body. There are also two gonadotrophic hormones which play a vital part in the control of the gonads: these are the follicle-stimulating hormone (FSH), and the luteinising hormone (LH) which is also known as the interstitial-cell-stimulating hormone (ICSH) – see GONADOTROPHINS. The lactogenic hormone, also known as prolactin, mammotrophin and luteotrophin, induces lactation.

The neurohypophysis produces two hormones. One is oxytocin, which is widely used because of its stimulating e?ect on contraction of the UTERUS. The other is VASOPRESSIN, or the antidiuretic hormone (ADH), which acts on the renal tubules and the collecting tubules (see KIDNEYS) to increase the amount of water that they normally absorb.... pituitary gland

Plantar Fasciitis

See FASCIITIS.... plantar fasciitis

Plaque

(1) A coating of the TEETH which forms as a result of poor mouth and dental hygiene. It consists of food debris and bacteria; later, calcium salts will be deposited in it to form calculus. It is therefore associated with both caries and periodontal disease (see TEETH, DISORDERS OF – Caries of the teeth).

(2) Raised patch on the skin resulting from the merging or enlargement of papules (see PAPULE; PIMPLES).... plaque

Plasma

The name applied to the straw-coloured ?uid portion of the BLOOD composed of a solution of various inorganic salts of sodium, potassium, calcium, etc., as well as SERUM and ?brinogen, the material which produces clotting (see COAGULATION). When the plasma is clotted, the thinner ?uid separating from the clot is the serum.... plasma

Placenta

The thick, spongy, disc-like mass of tissue which connects the EMBRYO with the inner surface of the UTERUS, the embryo otherwise lying free in the amniotic ?uid (see AMNION). The placenta is mainly a new structure growing with the embryo, but, when it separates, a portion of the inner surface of the womb – called the maternal placenta – comes away with it. It is mainly composed of loops of veins belonging to the embryo, lying in blood-sinuses, in which circulates maternal blood. Thus, although no mixing of the blood of embryo and mother takes place, there is ample opportunity for the exchange of ?uids, gases, and the nutrients brought by the mother’s blood. The width of the full-sized placenta is about 20 cm (8 inches), its thickness 2·5 cm (1 inch). One surface is rough and studded with villi, which consist of the loops of fetal veins; the other is smooth, and has implanted in its centre the umbilical cord, or navel string, which is about as thick as a ?nger and 50 cm (20 inches) long. It contains two arteries and a vein, enters the fetus at the navel, and forms the sole connection between the bodies of mother and fetus. The name ‘afterbirth’ is given to the structure because it is expelled from the womb in the third stage of labour (see PREGNANCY AND LABOUR).... placenta

Plague

This infection – also known as bubonic plague

– is caused by the bacterium Yersinis pestis. Plague remains a major infection in many tropical countries.

The reservoir for the bacillus in urban infection lies in the black rat (Rattus rattus), and less importantly the brown (sewer) rat (Rattus norvegicus). It is conveyed to humans by the rat ?ea, usually Xenopsylla cheopis: Y. pestis multiplies in the gastrointestinal tract of the ?ea, which may remain infectious for up to six weeks. In the pneumonic form (see below), human-to-human transmission can occur by droplet infection. Many lower mammals (apart from the rat) can also act as a reservoir in sylvatic transmission which remains a major problem in the US (mostly in the south-western States); ground-squirrels, rock-squirrels, prairie dogs, bobcats, chipmunks, etc. can be affected.

Clinically, symptoms usually begin 2–8 days after infection; disease begins with fever, headache, lassitude, and aching limbs. In over two-thirds of patients, enlarged glands (buboes) appear – usually in the groin, but also in the axillae and cervical neck; this constitutes bubonic plague. Haemorrhages may be present beneath the skin causing gangrenous patches and occasionally ulcers; these lesions led to the epithet ‘Black Death’. In a favourable case, fever abates after about a week, and the buboes discharge foul-smelling pus. In a rapidly fatal form (septicaemic plague), haematogenous transmission produces mortality in a high percentage of cases. Pneumonic plague is associated with pneumonic consolidation (person-to-person transmission) and death often ensues on the fourth or ?fth day. (The nursery rhyme ‘Ringo-ring o’ roses, a pocketful o’ posies, atishoo! atishoo!, we all fall down’ is considered to have originated in the 17th century and refers to this form of the disease.) In addition, meningitic and pharyngeal forms of the disease can occur; these are unusual. Diagnosis consists of demonstration of the causative organism.

Treatment is with tetracycline or doxycycline; a range of other antibiotics is also e?ective. Plague remains (together with CHOLERA and YELLOW FEVER) a quarantinable disease. Contacts should be disinfected with insecticide powder; clothes, skins, soft merchandise, etc. which have been in contact with the infection can remain infectious for several months; suspect items should be destroyed or disinfected with an insecticide. Ships must be carefully checked for presence of rats; the rationale of anchoring a distance from the quay prevents access of vermin. (See also EPIDEMIC; PANDEMIC; NOTIFIABLE DISEASES.)... plague

Plasmapheresis

See PLASMA EXCHANGE.... plasmapheresis

Plaster Of Paris

A form of calcium sulphate, which, after soaking in water, sets ?rmly. For this reason it is widely used as a form of splinting in the treatment of fractures, for producing casts to immobilise parts of the body, and for dental models. Splints are made with bandages impregnated with plaster and a suitable adhesive. Its great advantage, compared with an ordinary splint, is that it can be moulded to the shape of the limb.... plaster of paris

Plastic Surgery

See RECONSTRUCTIVE (PLASTIC) SURGERY.... plastic surgery

Plethora

A condition of fullness of the blood vessels in a particular part or in the whole body. This results in a ?orid, red appearance of the affected area, particularly the face. The volume of blood may be increased (POLYCYTHAEMIA) or the blood vessels beneath the skin may be dilated. Plethoric lung ?elds are seen on X-rays of patients with left-to-right shunts through the heart wall (see SEPTAL DEFECT).... plethora

Pleura

The name of the membrane which, on either side of the chest, forms a covering for one lung. The two pleurae are distinct, though they touch one another for a short distance behind the breast-bone. (See LUNGS.)... pleura

Pleurodynia

Also known as BORNHOLM DISEASE. A painful condition of the chest wall, it is usually the result of an infection of coxsackie virus B (see COXSACKIE VIRUSES) and may occur in epidemics (see EPIDEMIC). Fever, sore throat, headache and malaise are typical but the condition is self-limiting, subsiding within a few days.... pleurodynia

Plexus

A network of nerves or vessels: for example, the brachial and sacral plexuses of nerves and the choroid plexus of veins within the brain.... plexus

Pneumo

A pre?x relating to the LUNGS or to air. Examples are PNEUMONIA, PNEUMONECTOMY and PNEUMOPERITONEUM.... pneumo

Pneumococcus

A type of streptococcal bacterium (see STREPTOCOCCUS) which can cause otitis media (see EAR, DISEASES OF – Diseases of the middle ear), TONSILLITIS, PNEUMONIA, MENINGITIS and SEPTICAEMIA. It is usually sensitive to PENICILLIN.... pneumococcus

Pneumoconiosis

The general name applied to a chronic form of in?ammation of the LUNGS which is liable to affect people who constantly inhale irritating particles at work. It has been de?ned by the Industrial Injuries Advisory Council as: ‘Permanent alteration of lung structure due to the inhalation of mineral dust and the tissue reactions of the lung to its presence, but does not include bronchitis and emphysema.’ Some of the tradespeople liable to suffer are stonemasons, potters, steel-grinders, coal-miners, millers, and workers in cotton, ?ax, or wool mills. (See also OCCUPATIONAL HEALTH, MEDICINE AND DISEASES; TUBERCULOSIS.)... pneumoconiosis

Pneumonectomy

The operation of removing an entire lung (see LUNGS) in such diseases as BRONCHIECTASIS, TUBERCULOSIS, and cancer of the lung.... pneumonectomy

Pneumothorax

A collection of air in the pleural cavity, into which it has gained entrance by a defect in the lung or a wound in the chest wall. When air enters the chest, the lung immediately collapses towards the centre of the chest; but, air being absorbed from the pleural cavity, the lung expands again within a short time. (See LUNGS, DISEASES OF.)

Tension pneumothorax is a life-threatening condition in which the air in the hemithorax is under such pressure that it forces the heart to the other side and compresses the still-in?ated lung on the other side. It must be promptly relieved by inserting a hollow tube into the pleural cavity – a chest drain.

Arti?cial pneumothorax was an operation often performed in the pre-antibiotic days to treat pulmonary tuberculosis. Air was run into the pleural cavity to cause collapse of one lung, which rested it and allowed cavities in it to heal.... pneumothorax

Podiatry

The prevention, diagnosis, treatment and rehabilitation of medical and surgical conditions of the feet and lower limbs.... podiatry

Poison

A toxin which introduced to the body via the gastrointestinal tract or the respiratory tract.... poison

Polyarteritis Nodosa

Also known as periarteritis nodosa. A rare but potentially serious disease, probably caused by a disturbance of the immune system (see IMMUNITY). Prolonged fever and obscure symptoms referable to any system of the body are associated with local areas of in?ammation along the arteries, giving rise to nodules in their walls. Large doses of CORTICOSTEROIDS, coupled with IMMUNOSUPPRESSANT treatment, usually curtail the disorder. Recovery occurs in about 50 per cent of cases.... polyarteritis nodosa

Polyarthritis

Inflammation in several joints. Common features of a number of arboviral infections (e.g. Ross River virus and Barmah Forrest virus infections).... polyarthritis

Polydipsia

Excessive thirst, which is a symptom of DIABETES MELLITUS and some other diseases.... polydipsia

Polycythaemia

A rise in the amount of HAEMOGLOBIN in the blood. This may be caused by an excess in the number of ERYTHROCYTES produced in the BONE MARROW or to a fall in the total volume of PLASMA in the circulatory system. It may also be a response to reduced oxygen levels – for example, among people living at high altitudes – or to liver or kidney disease: this type is called secondary polycythaemia.

The disorder may, however, occur for no obvious reason and is then called polycythaemia vera. This type develops mainly in people over 40 and about 400 people develop the disorder every year in the United Kingdom. The blood thickens, the sufferer may develop high blood pressure, ?ushing, headaches, itching and an enlarged spleen. A stroke may occur later in the disease process. Treatment of polycythaemia vera is by regular removal of blood by VENESECTION, sometimes in combination with an anticancer drug. Secondary polycythaemia is treated by remedying the underlying cause.

Polycythaemia rubra vera A disorder in which the red blood cells increase in number along with an increase in the number of white blood cells and platelets. The cause is unknown. Severe cases may require treatment with CYTOTOXIC drugs or RADIOTHERAPY.... polycythaemia

Polymyalgia Rheumatica

A form of rheumatism characterised by gross early-morning sti?ness, which tends to ease o? during the day, and pain in the shoulders and sometimes around the hips. It affects women more than men, and is rare under the age of 60. The cause is still obscure. It responds well to PREDNISOLONE, but treatment may need to be long continued. On the other hand the condition is not progressive and does not lead to disability.... polymyalgia rheumatica

Polymyositis

A connective-tissue disease affecting the muscles throughout the body. This rare disorder, which is associated with DERMATOMYOSITIS, may be acute or chronic but it usually affects the muscles of the shoulders or hip areas. The muscles weaken and are tender to the touch. Di?use in?ammatory changes occur and symptomatic relief may be obtained with CORTICOSTEROIDS.... polymyositis

Polypeptide

A molecule in which several AMINO ACIDS are joined together by peptide bonds. PROTEIN molecules are polypeptides.... polypeptide

Pompholyx

See DERMATITIS.... pompholyx

Poppy

Two species are used in medicine: Papaver somniferum, the white opium-poppy (see OPIUM), and Papaver rhoeas, the red corn-poppy. The corn-poppy is chie?y used as a colouring agent, its syrup being a brilliant crimson colour.... poppy

Pore

A small opening. The word is usually used to describe an opening in the skin that releases sweat or sebum, a waxy material secreted by the sebaceous glands in the SKIN.... pore

Port Wine Stain

See NAEVUS.... port wine stain

Portal Hypertension

Raised blood pressure in the PORTAL VEIN entering the LIVER. This results in increased pressure in the veins of the oesophagus and upper stomach and these grow in size to form varices – dilated tortuous veins. Sometimes these varices rupture, causing bleeding into the oesophagus. The raised pressure also causes ?uid to collect in the abdomen and form ASCITES. The commonest reason for portal hypertension is cirrhosis (?brosis) of the liver (see LIVER, DISEASES OF). THROMBOSIS in the portal vein may also be a cause. Treatment requires the cause to be tackled, but bleeding from ruptured vessels may be stopped by injecting a sclerosant or hardening solution into and around the veins. Sometimes a surgical shunt may be done to divert blood from the portal vein to another blood vessel.... portal hypertension

Potassium

A metal which, on account of its great a?nity for other substances, is not found in a pure state in nature. Its salts are widely used in medicine but, as their action depends in general not on their metallic radical but upon the acid with which it is combined, their uses vary greatly and are described elsewhere. All salts of potassium depress the heart’s action as a result of action by the potassium ion.... potassium

Potassium Permanganate

A salt of the metallic element POTASSIUM. It is used as a skin antiseptic (see ANTISEPTICS) and for cleaning wounds; its astringent e?ect is useful in the treatment of DERMATITIS. It should not be taken internally because the compound is poisonous.... potassium permanganate

Prednisolone

A derivative of CORTISONE, which is ?ve or six times as active as cortisone and has less of the salt- and water-retaining properties of cortisone. It is given by mouth.... prednisolone

Premature Ejaculation

A disorder in which EJACULATION of semen occurs before or immediately after the penis penetrates the vagina during sexual intercourse. The most common sexual problem in men, persistent premature ejaculation may have psychological causes, although many adolescents and some adults experience it occasionally. Sexual counselling may help to alleviate the condition.... premature ejaculation

Premedication

A drug or drugs given to a patient to produce sedation before an operation, whether this is done under a local or general anaesthetic. A narcotic analgesic drug (see NARCOTICS; ANALGESICS) is usually used, as this relieves pain as well as anxiety. An antisecretory drug is often added to reduce the secretions in the airways and thus lessen the risk associated with general anaesthesia. Premedication reduces the amount of anaesthetic needed to make the patient unconscious.... premedication

Premolar

The two TEETH on each side of the jaw positioned between the canines and the molars in the adult. The teeth are used with the molars for holding and grinding food.... premolar

Premenstrual Syndrome

This has been de?ned as ‘any combination of emotional or physical features which occur cyclically in a woman before MENSTRUATION, and which regress or disappear during menstruation’. It is characterised by mood-changes, discomfort, swelling and tenderness in the breasts, swelling of the legs, a bloated feeling in the abdomen, headache, fatigue and constipation. The mood-changes range from irritability and mild depression to outbursts of violence. It may last for 3–14 days. How common it is is not known, as only the more severe cases are seen by doctors, but it has been estimated that one in ten of all menstruating women suffer from it severely enough to require treatment. The cause is not known, but it is probably due to some upset of the hormonal balance of the body. In view of the multiplicity of causes that have been put forward, it is not surprising that there is an equal multiplicity of treatments. Among these, one of the most widely used is PROGESTERONE. Others include pyridoxine, danazol, and gamma linolenic acid available in the form of oil of evening primrose. Whatever drug may be prescribed, counselling is equally essential and, in many cases, is all that is required.... premenstrual syndrome

Prepuce

Also known as the foreskin, this is the free fold of skin that overlaps the glans PENIS and retracts when the penis becomes erect. It is the part that is removed at CIRCUMCISION.... prepuce

Presbyacusis

DEAFNESS that comes on with increasing years. It is caused by increasing loss of elasticity in the hearing mechanism, combined with the slow-ing-down of the mental processes that accompanies old age. It is characterised by particular di?culty in hearing high notes such as the telephone and the voices of women and children. Hearing in a background of noise is also affected. Modern, miniaturised, transistor ‘within-the-ear’ hearing aids are now available that are proving helpful in making life more bearable for the elderly in this respect. (See also AGEING; HEARING AIDS.)... presbyacusis

Presbyopia

See ACCOMMODATION; EYE, DISORDERS OF.... presbyopia

Prescription

The written direction for drugs for medicinal use, given by the doctor, dentist and (for some drugs) nurse to the patient, for dispensation by the pharmacist. Drugs should only be prescribed when essential for treatment, and when any possible risks involved to the patient (and fetus in cases of pregnancy) are outweighed by the potential bene?ts of giving the drug. When possible, non-proprietary, or generic, titles should be prescribed; by allowing the pharmacist to dispense any equivalent drug this avoids delay for the patient, as well as reducing the cost to the Health Service. Dosage is generally stated in metric units, and both the amount and frequency should be carefully explained to the patient by the doctor, and clearly written when the drug is dispensed (see also DOSAGE; DRUGS). Strict adherence to the Misuse of Drugs Act 1973 is necessary to restrict the inappropriate prescription and abuse of drugs, particularly CONTROLLED DRUGS. Full details of drugs available on NHS prescription are given in the British National Formulary, which is published by the British Medical Association and the Royal Pharmaceutical Society of Great Britain twice a year and distributed to all NHS doctors by the government. Careful monitoring of prescribing in the UK is carried out by a government-appointed agency.... prescription

Pressor

An agent, neurologic or hormonal, that increases blood pressure.... pressor

Priapism

A persisting painful ERECTION of the PENIS occurring without sexual stimulation. It is a rare but acute condition that requires immediate treatment. The cause is the failure of blood to drain from the spongy corpus caversonum tissues of the penis, thus maintaining an erection. This may happen because of infection, damage to the nerves controlling the blood vessels, or a clotting defect in the blood.... priapism

Prickly Heat

See MILIARIA.... prickly heat

Primaquine

Used for radical cure of malaria and to prevent relapse. It is used to kill the liver stages of the malarial parasite. It also has the potential to be used as a causal prophylactic drug. This 8-aminoquinoline must be used with care or not at all in people who are G6PD deficient.... primaquine

Primary Prevention

The protection of health by personal and community-wide effects. Primary prevention involves measures provided to individuals to prevent the onset of a targeted condition.... primary prevention

Primidone

A barbiturate-related drug (see BARBITURATES) used to treat all forms of EPILEPSY, except in sufferers who do not have seizures.... primidone

Prion

An aberrant variety of one of the proteins, called PrP, in a brain cell. The result of a gene mutation (see GENES), prions are stable, resistant to radiation and impervious to the normal cellular processes of degradation. They seem to react with normal PrP, turning it into an abnormal type that then accumulates in brain tissue. Prions are believed to be the infectious agents that cause a group of serious neurological disorders called spongiform encephalopathies. CREUTZFELDT-JAKOB DISEASE (CJD), the new variant of CJD linked with BOVINE SPONGIFORM ENCEPHALOPATHY (BSE), and KURU – a neurological disorder found in a cannibal tribe in New Guinea – are all diseases in this group that occur in humans. The prion disorders have a long latent period between infection and manifestation of symptoms; they are hard to diagnose until autopsy and there is no cure as yet.... prion

Probenecid

A benzoic-acid derivative which interferes with the excretion by the KIDNEYS of certain compounds, including PENICILLIN and PARA-AMINO SALICYLIC ACID. Probenecid and was originally introduced into medicine for this reason, as a means of increasing and maintaining the concentration of penicillin in the body; it is also used to treat chronic GOUT.... probenecid

Procarbazine

An antineoplastic drug used mainly to treat Hodgkin’s disease (see under LYMPHOMA). It acts by interfering with the process of MITOSIS, the method by which the cells of the body, including tumours, reproduce themselves.... procarbazine

Prochlorperazine

Prochlorperazine is an antipsychotic phenothiazine drug (see NEUROLEPTICS). It is also an e?ective drug for the prevention or treatment of vomiting, and has therefore been used in the treatment of MENIÈRE’S DISEASE.... prochlorperazine

Procidentia

Another term for PROLAPSE.... procidentia

Proctalgia

Pain in the rectum... proctalgia

Proctitis

In?ammation situated about the RECTUM or ANUS.... proctitis

Prodrome

A premonitory symptom or precursor; a symptom indicating the onset of a disease.... prodrome

Progeria

Premature old age (see also AGEING).... progeria

Progesterone

This is the hormone secreted after ovulation by the corpus luteum. It is a steroid (a cholesterol with a funny hat), enters receptive cells to stimulate their growth, and acts as an anabolic agent. Estrogen should be viewed as the primary coat underneath all the cycles during a woman’s reproductive years, with progesterone, its antagonist, surging for ten or twelve days in ovulatory months. Most of the actions of progesterone cannot occur without estrogen having previously induced the growth of progesterone-receptive binding sites. In the estrus cycle, estrogen stimulates the thickening of membranes (the proliferative phase), and progesterone stimulates their sophistication into organized and secreting mucosa (the secretory phase). The new secretions contain anticoagulants, antimicrobials, and rich mucus fluids. If there is pregnancy, the uterine membranes are fully structured for the long haul; if menses occurs, the thickened tissues can erode away without clotting, becoming infected, or flowing poorly. If there is not enough estrogen, the corpus luteum will not mature. If the corpus luteum is weak, menses becomes disorganized, clotty, and painful. It is also the first part of the cycle to become disorganized in early menopause, since the available ovarian proto-follicles have been reduced over the years to only a few. In earlier years, dozens of potential follicles may attempt maturity each month, with only the strongest one able to reach dominance, form a corpus luteum and an ovum...the rest disintegrating. In a manner of speaking, the better the follicle, the better the corpus luteum and (presumably) the sounder the ovum. Since the number of potential follicles is fixed at birth, by early menopause those that still remain contain a high number of hormone-resistant and unsound protofollicles, resulting in more and more cycles having less predictable estrogen and especially progesterone levels.... progesterone

Prognathism

Abnormal protusion of the lower JAW, or sometimes of both jaws. The condition may make biting and chewing di?cult, in which case corrective surgery is necessary.... prognathism

Proguanil

A biguanide antimalarial used alone or in combination for the prevention of malaria.... proguanil

Prolactin

Prolactin is the pituitary hormone (see PITUITARY GLAND) which initiates lactation. The development of the breasts during pregnancy is ascribed to the action of OESTROGENS; prolactin starts them secreting. If lactation does not occur or fails, it may be started by injection of prolactin.

The secretion of prolactin is normally kept under tonic inhibition by the secretion of DOPAMINE which inhibits prolactin. This is formed in the HYPOTHALAMUS and secreted into the portal capillaries of the pituitary stalk to reach the anterior pituitary cells. Drugs that deplete the brain stores of dopamine or antagonise dopamine at receptor level will cause HYPERPROLACTINAEMIA and hence the secretion of milk from the breast and AMENORRHOEA. METHYLDOPA and RESERPINE deplete brain stores of dopamine and the PHENOTHIAZINES act as dopamine antagonists at receptor level. Other causes of excess secretion of prolactin are pituitary tumours, which may be minute and are then called microadenomas, or may actually enlarge the pituitary fossa and are then called macroadenomas. The most common cause of hyperprolactinaemia is a pituitary tumour. The patient may present with infertility – because patients with hyperprolactinaemia do not ovulate – or with amenorrhea and even GALACTORRHOEA.

BROMOCRIPTINE is a dopamine agonist. Treatment with bromocriptine will therefore control hyperprolactinaemia, restoring normal menstruation and ovulation and suppressing galactorrhoea. If the cause of hyperprolactinaemia is an adenomatous growth in the pituitary gland, surgical treatment should be considered.... prolactin

Prolapse

Displacement of an organ or structure from its normal position. The term is applied chie?y to downward displacements of the RECTUM and UTERUS.... prolapse

Promazine

A phenothiazine drug used to tranquillise disturbed patients (see NEUROLEPTICS).... promazine

Pronation

The movement whereby the bones of the forearm are crossed and the palm of the hand faces downwards.... pronation

Proptosis

A condition in which the EYE protrudes from the orbit. Some causes include thyroid disorders (see THYROID GLAND, DISEASES OF), tumours within the orbit, in?ammation or infection of the orbit. Proptosis due to endocrine abnormality (e.g. thyroid problems) is known as EXOPHTHALMOS.... proptosis

Propylthiouracil

An oral antithyroid drug given daily to a person with HYPERTHYROIDISM. It interferes with the body’s production of thyroid hormones.... propylthiouracil

Prospective Study

See “cohort study”.... prospective study

Prostaglandin

A group of a dozen or more fatty acid derivatives made by many tissues for paracrine (local) hormone use. Because they are only meant for local use, the same compound may serve opposite purposes in different tissues...inhibiting inflammation in the stomach lining while increasing uterine irritability.... prostaglandin

Prostate Gland

This is an accessory sex gland in males which is wrapped round the URETHRA as this tube leaves the URINARY BLADDER. Opening into the urethra, the gland secretes an alkaline ?uid during ejaculation and is a constituent of SEMEN. The gland grows during adolescence and is sensitive to the concentrations of sex hormones.... prostate gland

Prostatectomy

An operation to remove part or all of the PROSTATE GLAND. The most common method is transurethral prostatectomy (TURP) carried out during cytoscopy. A very enlarged prostate may need to be removed by a retropubic prostatectomy. After several weeks, most patients are able to resume normal activity including sexual intercourse.... prostatectomy

Protein

Molecular constituent of all cells comprising amino acid building blocks.... protein

Protoplasm

The viscid, translucent, glue-like material containing ?ne granules and composed mainly of proteins, which makes up the essential material of plant and animal cells and has the properties of life.... protoplasm

Prosthesis

An arti?cial replacement of a missing or malfunctioning body part. Examples include false legs or arms ?tted after AMPUTATION (see below); arti?cial heart valves; arti?cial heart devices; COCHLEAR IMPLANTS to improve hearing; a bio-arti?cial PANCREAS (containing live pancreatic cells from pigs) now under development to treat DIABETES MELLITUS; arti?cial bone; and (under development) arti?cal lungs. Cosmetic prostheses such as arti?cal eyes, teeth, noses and breasts are in widespread use.

Development of such mechanical and biomechanical devices points the way to a much wider use of e?ective prostheses, enabling people who would previously have died or been severely handicapped to lead normal or near normal lives. The technical hazards that have already been overcome provide a sound foundation for future successes. Progress so far in producing prostheses should also ensure that organ replacement is free from the serious ethical problems that surround the use of genetic manipulation to cure or prevent serious diseases (see ETHICS).

Limbs These are best made to meet the individual’s requirements but can be obtained ‘o? the shelf’. Arti?cial joints normally comprise complex mechanisms to stimulate ?exion and rotation movements. Leg prostheses are generally more useful than those for arms, because leg movements are easier to duplicate than those of the arm. Modern electronic circuitry that enables nerve impulses to be picked up and converted into appropriate movements is greatly improving the e?ectiveness of limb prostheses.

Eyes Arti?cial eyes are worn both for appearance and for psychological reasons. They are made of glass or plastic, and are thin shells of a boat-shape, representing the front half of the eye which has been removed. The stump which is left has still the eye-muscles in it, and so the arti?cial eye still has the power of moving with the other. A glass eye has to be replaced by a new one every year. Plastic eyes have the advantage of being more comfortable to wear, being more durable, and being unbreakable. Research is taking place aimed at creating a silicon chip that stimulates the visual cortex and thus helps to restore sight to the blind.

Dental prostheses is any arti?cial replacement of a tooth. There are three main types: a crown, a bridge and a denture. A crown is the replacement of the part of a tooth which sticks through the gum. It is ?xed to the remaining part of the tooth and may be made of metal, porcelain, plastic or a combination of these. A bridge is the replacement of two or three missing teeth and is usually ?xed in place. The replacement teeth are held in position by being joined to one or more crowns on the adjacent teeth. A denture is a removable prosthesis used to replace some or all the teeth. The teeth are made of plastic or porcelain and the base may be of plastic or metal. Removable teeth may be held more ?rmly by means of implants.

Heart The surgical replacement of stenosed or malfunctioning heart-valves with metal or plastic, human or pig valves has been routinely carried out for many years. So too has been the insertion into patients with abnormal heart rhythms of battery-driven arti?cial pacemakers (see CARDIAC PACEMAKER) to restore normal function. The replacement of a faulty heart with an arti?cial one is altogether more challenging. The ?rst working attempt to create an arti?cial heart took place in the early 1980s. Called the Jarvik-7, it had serious drawbacks: patients had to be permanently connected to apparatus the size of an anaesthetic trolley; and it caused deaths from infection and clotting of the blood. As a result, arti?cial hearts have been used primarily as bridging devices to keep patients alive until a suitable donor heart for transplantation can be found. Recent work in North America, however, is developing arti?cial hearts made of titanium and dacron. One type is planted into the chest cavity next to the patient’s own heart to assist it in its vital function of pumping blood around the body. Another replaces the heart completely. Eventually, it is probable that arti?cial hearts will replace heart transplants as the treatment of choice in patients with serious heart disorders.

Liver Arti?cial livers work in a similar way to kidney dialysis machines (see DIALYSIS). Blood is removed from the body and passed through a machine where it is cleaned and treated and then returned to the patient. The core of the device comprises several thousand ?exible membrane tubules on which live liver cells (from pigs or people) have been cultured. There is an exchange of biological molecules and water with the ‘circulating’ blood, and the membrane also screens the ‘foreign’ cells from the patient’s immune system, thus preventing any antagonistic immune reaction in the recipient.

Nose The making of a new nose is the oldest known operation in plastic surgery, Hindu records of such operations dating back to 1,000 BC. Loss of a nose may be due to eroding disease, war wounds, gun-shot wounds or dog bites. In essence the operation is the same as that practised a thousand years before Christ: namely the use of a skin graft, brought down from the forehead. Alternative sources of the skin graft today are skin from the arm, chest or abdomen. As a means of support, the new nose is built round a graft of bone or of cartilage from the ear.... prosthesis

Pseudocyesis

Pseudocyesis means spurious or false pregnancy, a condition characterised by enlargement of the abdomen, and even enlargement of the breasts and early-morning sickness – the woman being quite convinced that she is pregnant.... pseudocyesis

Psittacosis

Also called parrot disease. An infectious disease of parrots and other exotic birds which may be transmitted to humans and is caused by the micro-organism Chlamydia psittaci. It presents as PNEUMONIA or a systemic illness in which the patient has an enlarged spleen and liver and PNEUMONITIS. Tetracycline is an e?ective treatment, but relapses may occur.... psittacosis

Psychoanalysis

The term applied to the theories and practice of the school of psychology originating with Freud and developed by Jung and other psychotherapists (see PSYCHOLOGY). It depends upon the theory that states of disordered mental health have been produced by a repression in the subconscious of painful memories or of con?icting instincts, thus absorbing the individual’s mental energy and diverting attention from normal mental activities.

Psychoanalysis aims at discovering these repressed memories, which are responsible for the diversion of mental power and of which the affected person usually is only dimly aware or quite unaware. The fundamental method of psychoanalytical treatment is the free expression of thoughts, ideas and fantasies on the part of the patient. To facilitate this, the analyst uses techniques to relax the patient and maintains a neutral attitude to his or her problems. In the course of analysis the patient will re-explore his or her early emotional attitudes and tensions.

The fundamental conception of psychoanalysis, although hard to prove by orthodox scienti?c methods and therefore challenged by some psychiatrists, has been widely adopted and developed by other schools of psychology. Freud’s work changed the attitudes of the scienti?c community and the public to the problems of the neurotic, the morbidly anxious, the fearful and to the mental and emotional develoment of the child.... psychoanalysis

Psychosis

One of a group of mental disorders in which the affected person loses contact with reality. Thought processes are so disturbed that the person does not always realise that he or she is ill. Symptoms include DELUSIONS, HALLUCINATIONS, loss of emotion, MANIA, DEPRESSION, poverty of thought and seriously abnormal behaviour. Psychoses include SCHIZOPHRENIA, MANIC DEPRESSION and organically based mental disorders. (See also MENTAL ILLNESS.)... psychosis

Pterygium

A degenerative disorder of the conjunctiva (see EYE) which grows over the cornea medially and laterally. The overgrowths look like wings. They are commonly seen in people who live in areas of bright sunlight, particularly when re?ected from deserts or snow?elds. Treatment involves excision of the overgrowth. (See also EYE, DISORDERS OF.)... pterygium

Psychosurgery

This was introduced in 1936 by Egas Moniz, Professor of Medicine in Lisbon University, for the surgical treatment of certain psychoses (see PSYCHOSIS). For his work in this ?eld he shared the Nobel prize in 1949. The original operation, known as leucotomy, consisted of cutting white ?bres in the frontal lobe of the BRAIN. It was accompanied by certain hazards such as persistent EPILEPSY and undesirable changes in personality; pre-frontal leucotomy is now regarded as obsolete. Modern stereotactic surgery may be indicated in certain intractable psychiatric illnesses in which the patient is chronically incapacitated, especially where there is a high suicide risk. Patients are only considered for psychosurgery when they have failed to respond to routine therapies. One contraindication is marked histrionic or antisocial personality. The conditions in which a favour-able response has been obtained are intractable and chronic obsessional neuroses (see NEUROSIS), anxiety states and severe chronic DEPRESSION.

Psychosurgery is now rare in Britain. The Mental Health Act 1983 requires not only consent by the patient – con?rmed by an independent doctor, and two other representatives of the Mental Health Act Commission – but also that the Commission’s appointed medical representative also advise on the likelihood of the treatment alleviating or preventing a deterioration in the patient’s condition.... psychosurgery

Ptyalism

Excessive secretion of saliva... ptyalism

Public Health

The approach to health that is concerned with the health of the community as a whole. The three core public health functions are: the assessment and monitoring of the health of communities and populations at risk to identify health problems and priorities; the formulation of public policies designed to solve identified local and national health problems and priorities; and ensuring that all populations have access to appropriate and cost-effective care, including health promotion and disease prevention services, and evaluation of the effectiveness of that care. See “community health”.... public health

Puberty

The change that takes place when childhood passes into manhood or womanhood. This change is generally a very de?nite one, occurring at about the age of 14 years, although it is modi?ed by race, climate, and bodily health so that it may appear a year or two earlier or several years later. At this time, the sexual functions attain their full development; the contour of the body changes from a childish to a more rounded womanly, or sturdy manly, form; and great changes take place in the mode of thought and feeling.

In girls, puberty is marked by the onset of MENSTRUATION and development of the BREASTS. The latter is usually the ?rst sign of puberty to appear, and may occur from nine years onwards; most girls show signs of breast development by the age of 13. The time from the beginning of breast development to the onset of menstruation is usually around two years but may range from six months to ?ve years. The ?rst sign of puberty in boys is an increase in testicular and penile size (see TESTICLE; PENIS) between the age of ten and 14. The LARYNX enlarges in boys, so that the voice – after going through a period of ‘breaking’ – ?nally assumes the deep manly pitch. Hair appears on the pubis and later in the armpits in both boys and girls, whilst in the former it also begins to grow on the upper lip, and skin eruptions are not uncommon on the face (see ACNE).

The period is one of transition from a physical and mental point of view. Puberty is not to be regarded as a physiological ‘coming of age’, for full development is usually achieved in the early 20s.... puberty

Pulmonary Hypertension

In this condition, increased resistance to the blood ?ow through the LUNGS occurs. This is usually the result of lung disease, and the consequence is an increase in pulmonary artery pressure and in the pressure in the right side of the heart and in the veins bringing blood to the heart. Chronic BRONCHITIS or EMPHYSEMA commonly constrict the small arteries in the lungs, thus causing pulmonary HYPERTENSION. (See also EISENMENGER SYNDROME.)... pulmonary hypertension

Pulmonary Oedema

Fluid in the small air sacs of the lungs, from inefficient pumping by the heart or leakage of fluid from the blood vessels in the lungs (possibly from envenomation). As it prevents air exchange in the lungs it causes hypoxia and may lead to death.... pulmonary oedema

Puerperium

The period which elapses after the birth of a child until the mother is again restored to her ordinary health. It is generally regarded as lasting for a month. One of the main changes to occur is the enormous decrease in size that takes place in the muscular wall of the womb. There are often AFTERPAINS during the ?rst day in women who have borne several children, less often after a ?rst child. The discharge is bloodstained for the ?rst two or three days, then clearer till the end of the ?rst week, before stopping within two or three weeks. The breasts, which have already enlarged before the birth of the child, secrete milk more copiously, and there should be a plentiful supply on the third

day of the puerperium. (See also PREGNANCY AND LABOUR.)

Management The mother should start practising exercises to help ensure that the stretched abdominal muscles regain their normal tone. There is no need for any restriction of diet, but care must be taken to ensure an adequate intake of ?uid, including at least 580 ml (a pint) of milk a day.

Milk, as already stated, appears copiously on the third day, but this is preceded by a secretion from the breast, known as colostrum, which is of value to the newborn child. The child should therefore be put to the breasts within 6–8 hours of being born. This also stimulates both the breasts and the natural changes taking place during this period. Suckling is bene?cial for both child and mother and encourages bonding between the two.... puerperium

Pulmonary Embolism

The condition in which an embolus (see EMBOLISM), or clot, is lodged in the LUNGS. The source of the clot is usually the veins of the lower abdomen or legs, in which clot formation has occurred as a result of the occurrence of DEEP VEIN THROMBOSIS (DVT) – THROMBOPHLEBITIS (see VEINS, DISEASES OF). Thrombophlebitis, with or without pulmonary embolism, is a not uncommon complication of surgical operations, especially in older patients. This is one reason why nowadays such patients are got up out of bed as quickly as possible, or, alternatively, are encouraged to move and exercise their legs regularly in bed. Long periods of sitting, particularly when travelling, can cause DVT with the risk of pulmonary embolism. The severity of a pulmonary embolism, which is characterised by the sudden onset of pain in the chest, with or without the coughing up of blood, and a varying degree of SHOCK, depends upon the size of the clot. If large enough, it may prove immediately fatal; in other cases, immediate operation may be needed to remove the clot; whilst in less severe cases anticoagulant treatment, in the form of HEPARIN, is given to prevent extension of the clot. For some operations, such as hip-joint replacements, with a high risk of deep-vein thrombosis in the leg, heparin is given for several days postoperatively.... pulmonary embolism

Pulmonary Stenosis

A disorder of the HEART in which obstruction of the out?ow of blood from the right ventricle occurs. Narrowing of the pulmonary valve at the exit of the right ventricle and narrowing of the pulmonary artery may cause obstruction. The condition is usually congenital, although it may be caused by RHEUMATIC FEVER. In the congenital condition, pulmonary stenosis may occur with other heart defects and is then known as Fallot’s tetralogy. Breathlessness and enlargement of the heart and eventual heart failure may be the consequence of pulmonary stenosis. Surgery is usually necessary to remove the obstruction.... pulmonary stenosis

Pulse

If the tip of one ?nger is laid on the front of the forearm, about 2·5 cm (one inch) above the wrist, and about 1 cm (half an inch) from the outer edge, the pulsations of the radial artery can be felt. This is known as the pulse, but a pulse can be felt wherever an artery of large or medium size lies near the surface.

The cause of the pulsation lies in the fact that, at each heartbeat, 80–90 millilitres of blood are driven into the AORTA, and a ?uid wave, distending the vessels as it passes, is transmitted along the ARTERIES all over the body. This pulsation falls away as the arteries grow smaller, and is ?nally lost in the minute capillaries, where a steady pressure is maintained. For this reason, the blood in the veins ?ows steadily on without any pulsation. Immediately after the wave has passed, the artery, by virtue of its great elasticity, regains its former size. The nature of this wave helps the doctor to assess the state of the artery and the action of the heart.

The pulse rate is usually about 70 per minute, but it may vary in health from 50 to 100, and is quicker in childhood and slower in old age than in middle life; it is low (at rest) in physically ?t athletes or other sports people. Fever causes the rate to rise, sometimes to 120 beats a minute or more.

In childhood and youth the vessel wall is so thin that, when su?cient pressure is made to expel the blood from it, the artery can no longer be felt. In old age, however, and in some degenerative diseases, the vessel wall becomes so thick that it may be felt like a piece of whipcord rolling beneath the ?nger.

Di?erent types of heart disease have special features of the pulse associated with them. In atrial FIBRILLATION the great character is irregularity. In patients with an incompetent AORTIC VALVE the pulse is characterised by a sharp rise and sudden collapse. (See HEART, DISEASES OF.)

An instrument known as the SPHYGMOGRAPH registers the arterial waves and a polygraph (an instrument that obtains simultaneous tracings from several di?erent sources such as radial and jugular pulse, apex beat of the heart and ELECTROCARDIOGRAM (ECG)) enables tracings to be taken from the pulse at the wrist and from the veins in the neck and simultaneous events in the two compared.

The pressure of the blood in various arteries is estimated by a SPHYGMOMANOMETER. (See BLOOD PRESSURE.)... pulse

Pupil

See EYE.... pupil

Purpura

A skin rash caused by bleeding into the skin from capillary blood vessels. The discrete purple spots of the rash are called purpuric spots or, if very small, petechiae. The disorder may be caused by capillary defects (nonthrombocytopenic purpura) or be due to a de?ciency of PLATELETS in the blood (thrombocytopenic purpura). Most worryingly, the rash may be due to a fulminant form of meningococcal SEPTICAEMIA called purpura fulminans. (See also HENOCH-SCHÖNLEIN PURPURA; IDIOPATHIC THROMBOCYTOPENIC PURPURA (ITP); THROMBOCYTOPENIA.).... purpura

Purulent

Containing, comprising or forming PUS.... purulent

Pustule

A small collection of PUS. Malignant pustule is one of the forms of ANTHRAX.... pustule

Puva

See PHOTOCHEMOTHERAPY; PSORIASIS.... puva

Pyelography

The process whereby the KIDNEYS are rendered radio-opaque, and therefore visible on an X- ray ?lm. It constitutes a most important part of the examination of a patient with kidney disease. (See SODIUM DIATRIZOATE.)... pyelography

Pyelolithotomy

Surgery to remove a stone from the kidney (see KIDNEYS, DISEASES OF) via an incision in the pelvis of the kidney.... pyelolithotomy

Pyelonephritis

In?ammation of the kidney (see KIDNEYS), usually the result of bacterial infection. The in?ammation may be acute or chronic. Acute pyelonephritis comes on suddenly, is commoner in women, and tends to occur when they are pregnant. Infection usually spreads up the URETER from the URINARY BLADDER which has become infected (CYSTITIS). Fevers, chills and backache are the usual presenting symptoms. ANTIBIOTICS should be given, and in severe cases the intravenous route may be necessary. SEPTICAEMIA is an occasional complication.

Chronic pyelonephritis may start in childhood, and the usual cause is back ?ow of urine from the bladder into one of the ureters – perhaps because of a congenital deformity of the valve where the ureter drains into the bladder. Constant urine re?ux results in recurrent infection of the kidney and damage to its tissue. Full investigation of the urinary tract is essential and, if an abnormality is detected, surgery may well be required to remedy it. HYPERTENSION and renal failure may be serious complications of pyelonephritis (see also KIDNEYS, DISEASES OF).... pyelonephritis

Pyloric Stenosis

Narrowing of the PYLORUS, the muscular exit from the STOMACH. It is usually the result of a pyloric ulcer or cancer near the exit of the stomach. Food is delayed when passing from the stomach to the duodenum and vomiting occurs. The stomach may become distended and peristalsis (muscular movement) may be seen through the abdominal wall. Unless surgically treated the patient will steadily deteriorate, losing weight, becoming dehydrated and developing ALKALOSIS.

A related condition, congenital hypertrophic pyloric stenosis, occurs in babies (commonly boys) about 3–5 weeks old, and surgery produces a complete cure.... pyloric stenosis

Pyoderma Gangrenosum

This is a disorder in which large ulcerating lesions appear suddenly and dramatically in the skin. It is the result of underlying VASCULITIS. It is usually the result of in?ammatory bowel disease such as ULCERATIVE COLITIS or CROHN’S DISEASE but can be associated with RHEUMATOID ARTHRITIS.... pyoderma gangrenosum

Pyrazinamide

An antituberculous drug used in combination, usually with RIFAMPICIN and ISONIAZID, as the treatment regime for TUBERCULOSIS. It penetrates the MENINGES so is valuable in treating tuberculous MENINGITIS. The drug is sometimes associated with liver damage and liver function tests should be done before using it.... pyrazinamide

Pyridoxine

Pyridoxine, or vitamin B, plays an important part in the metabolism of a number of AMINO ACIDS. De?ciency leads to ATROPHY of the EPIDERMIS, the hair follicles, and the SEBACEOUS glands, and peripheral NEURITIS may also occur. Young infants are more susceptible to pyridoxine de?ciency than adults: they begin to lose weight and develop a hypochromic ANAEMIA; irritability and CONVULSIONS may also occur. Liver, yeast and cereals are relatively rich sources of the vitamin; ?sh is a moderately rich source, but vegetables and milk contain little. The minimal daily requirement in the diet is probably about 2 mg. (See APPENDIX 5: VITAMINS.)... pyridoxine

Pyrimethamine

An antimalarial drug used with either sulfadoxine or DAPSONE to treat Plasmodium falciparum malariae (see MALARIA). It should not be used for PROPHYLAXIS because of potentially severe side-effects when used in the long term.... pyrimethamine

Pyuria

The presence of PUS in the URINE, in consequence of in?ammation situated in the KIDNEYS, URINARY BLADDER or other part of the urinary tract.... pyuria

Referred Pain

Pain felt in one part of the body which is actually arising from a distant site (e.g. pain from the diaphragm is felt at the shoulder tip). This occurs because both sites develop from similar embryological tissue and therefore have

common pain pathways in the CENTRAL NERVOUS SYSTEM. (See also PAIN.)... referred pain

Recovery Position

If an individual is unconscious – whether as a result of accident or illness or when in the postoperative recovery unit – but is breathing and has a pulse, he or she should be placed in the recovery position. The individual is turned on his or her side to allow the tongue to fall forwards and so reduce the likelihood of pharyngeal obstruction (see PHARYNX). Fluid in the mouth can also drain outwards instead of into the TRACHEA and LUNGS. The person can lie on either side with upper or lower leg ?exed. Sometimes the semi-prone position is used; this gives better drainage from the mouth and greater stability during transport, but makes it more di?cult to observe the face, colour or breathing. (See APPENDIX 1: BASIC FIRST AID.)... recovery position

Safe Period

That period during the menstrual cycle (see MENSTRUATION) when fertilisation of the OVUM is unlikely to occur. OVULATION usually occurs about 15 days before the onset of the menstrual period. A woman is commonly believed to be fertile for about 11 days in each menstrual cycle – in other words, on the day of ovulation and for ?ve days before and ?ve days after this; this would be the eighth to the 18th day of the usual 28-day menstrual cycle. Outside this fertile period is the SAFE PERIOD: the ?rst week and the last ten days of the menstrual cycle. On the other hand, there is increasing evidence that the safest period is the last few days before menstruation. In the case of irregular menstruation it is not possible to calculate the safe period. In any event, the safety is not absolute. (See also CONTRACEPTION.)... safe period

Solar Plexus

A large network of sympathetic nerves and ganglia situated in the abdomen behind the stomach, where it surrounds the coeliac artery. Branches of the VAGUS nerve – the most important part of the PARASYMPATHETIC NERVOUS SYSTEM – lead into the solar plexus, which in turn distributes branches to the stomach, intestines and several other abdominal organs. A severe blow in the solar plexus may cause temporary unconsciousness.... solar plexus

Tertiary Prevention

A process aimed at limiting the negative effects of an established disease.... tertiary prevention

Tubal Pregnancy

Also known as ECTOPIC PREGNANCY. Implantation of the EMBRYO in one of the FALLOPIAN TUBES, rather than in the lining of the UTERUS. The patient usually complains of pain between six and ten weeks’ gestation and, if the Fallopian tube is not removed, there may be rupture with potentially life-threatening haemorrhage.... tubal pregnancy

Bell’s Palsy

Paralysis of the 7th (facial) nerve which controls muscles of the face. One-sided stiffness and distortion of the face which lacks expression. Inability to close eyes or whistle. Rarely painful.

Aetiology. Injury, virus infection, cold, stroke. Recovery usually spontaneous. Herpes Simp. Alternatives. Chamomile, Wood Betony, Bryonia, Black Cohosh, Barberry, Asafoetida, Lobelia, Rosemary, Valerian, Sage. Echinacea has been used with convincing results internally and externally.

Tea. Equal parts. Chamomile, Wood Betony. Sage. 1 heaped teaspoon to each cup boiling water; infuse 15 minutes. 1 cup 3 times daily.

Decoctions. Black Cohosh, Rosemary, Valerian, Echinacea.

Tablets/capsules. Black Cohosh. Ginseng. Echinacea. Valerian.

Powders. Formula. Rosemary 1; Echinacea 2; Valerian 1. Dose: 500mg (two 00 capsules or one-third teaspoon) thrice daily.

Tinctures. Formula. Echinacea 2; Rosemary 1; Black Cohosh 1; Pinch Tincture Capsicum. 1-2 teaspoons 3 times daily.

Evening Primrose oil. 4 × 500mg capsules daily.

Aromatherapy. 10 drops Oil Juniper to eggcup Almond oil; gentle massage affected side of face. Diet. Lacto-vegetarian.

Vitamin E. (400iu daily). ... bell’s palsy

Papain

See: PAPAYA. ... papain

Parathyroid Glands

Glands that control the level of calcium in the blood. The four glands appear, two on each side, implanted in the thyroid gland in the front of the neck.

Disorders are (1) hypoparathyroidism and (2) hyperparathyroidism. See entries. ... parathyroid glands

Lichen Planus

An inflammatory skin eruption with small shiny pimples starting from the wrists and spreading towards the trunk. Associated with lesions on mucous surfaces – vulva, penis, mouth. Cause is unknown but sometimes related to tuberculosis or drug poisoning. Usually over front of wrists, trunk and shins.

Symptoms: Severe itching. Thickened skin with shiny red patches which later become brown and scaly. Distinguish from psoriasis. Nails ridged and split.

Alternatives. Relief from itching by use of antihistamines: Garlic, Goldenseal, Ephedra, Lobelia.

Teas. Nettles, Boneset, Chickweed, Heartsease, Yucca.

Decoctions. (1) Combine: equal parts: Burdock, Sarsaparilla, Passion flower. OR (2) Combine: equal parts: Echinacea, Blue Flag root, Sarsaparilla. Half an ounce (14g) to 1 pint (500ml) water gently simmered 20 minutes. Dose: half-1 cup thrice daily.

Cold infusion. One heaped teaspoon Barberry (Berberis Vul) to cup cold water. Steep overnight. Half-1 cup thrice daily.

Powders, Liquid Extracts or Tinctures. Equal parts: Wild Yam, Blue Flag root, Fringe Tree bark. Powders: 500mg. Liquid Extracts: 30-60 drops in water. Tinctures: 1-2 teaspoons in water. Thrice daily before meals.

Mouth ulcers: Rinse mouth with Goldenseal and Myrrh drops, in water.

Topical. Ointment or pulp from any one: Aloe Vera, Comfrey, Chickweed, Houseleek, Marshmallow. Vaginal lesion. Aloe Vera pulp or gel.

Diet. Avoid citrus fruits and milk.

Vitamins. A. B-complex, B12, C. E. F. PABA.

Minerals. Dolomite. Zinc. Cod Liver oil: one dessertspoon daily. ... lichen planus

Paget’s Disease

(Sir James Paget, 1814-99) Osteitis deformans. Chronic inflammation of bone at focal points (Pagetic sites), often widespread. Chronic. Progressive softening followed by thickening with distortion. Renewal of new bone outstrips absorption of old bone. Enlargement of the skull (‘Big head’) and of the long bones. Broadened pelvis, distorted spine (kyphosis) from flattened vertebra. Male predominence. Over 40 years. Spontaneous fractures possible. Paget’s disease and diabetes may be associated in the same family.

Some authorities believe cause is vitamin and mineral deficiency – those which promote bone health being calcium and magnesium (dolomite). Supplementation helps cases but evidence confirms that some pet-owners are at risk – a virus from cats and dogs possibly responsible. The prime candidate is one exposed to canine distemper. Dogs are involved twice as much as cats. The virus is closely related to the measles virus in humans.

Symptoms. Limbs deformed, hot during inflammatory stage. Headaches. Dull aching pain in bones. Deafness from temporal bone involvement. Loss of bone rigidity. Bowing of legs.

Surgical procedures may be necessary. Appears to be a case for immunisation of dogs against distemper.

Alternatives. Black Cohosh, Boneset, Cramp bark, Bladderwrack, German Chamomile, Devil’s Claw, Helonias, Oat husks, Prickly Ash, Sage, Wild Yam.

Tea. Oats (mineral nutrient for wasting diseases) 2; Boneset (anti-inflammatory) 1; Valerian (mild analgesic) 1; Liquorice quarter. Mix. 1 heaped teaspoon to each cup boiling water; infuse 15 minutes. 1 cup thrice daily.

Decoction. Cramp bark 1; White Willow 2. Mix. 4 heaped teaspoons to 1 pint (500ml) water gently simmered 20 minutes. Dose: half-1 cup thrice daily.

Tablets/capsules. Cramp bark, Devil’s Claw, Echinacea, Helonias, Prickly Ash, Wild Yam.

Formula. Devil’s Claw 1; Black Cohosh 1; Valerian 1; Liquorice quarter. Dose: Powders: 500mg (two 00 capsules or one-third teaspoon). Liquid extracts: 1 teaspoon. Tinctures: 2 teaspoons. Action enhanced when taken in cup of Fenugreek tea. Thrice daily. Every 2 hours acute cases.

Practitioner’s analgesic. Tincture Gelsemium: 10 drops in 100ml water. Dose: 1 teaspoon every 2 hours (inflammatory stage).

Topical. Comfrey root poultice.

Diet. High protein, low salt, low fat. Oily fish.

Supplements. Daily. Vitamin C (500mg); Vitamin D (1000mg); Calcium citrate (1 gram); Dolomite (1 gram); Beta-Carotene (7500iu). Kelp. ... paget’s disease

Psychosomatic

A term that describes physical disorders that seem to have been caused, or made worse, by psychological factors. Common examples of conditions that may be psychosomatic are headache, breathlessness, nausea, asthma, irritable bowel syndrome, peptic ulcer, and types of eczema. (See also somatization disorder.)... psychosomatic

Argyll Robertson Pupil

A condition (described originally by Dr Argyll Robertson) in which the pupils contract when the eyes converge on a near object, but fail to contract when a bright light falls on the eye. It is found in several diseases, especially in locomotor ataxia and neurosyphilis, an advanced manifestation of SYPHILIS.... argyll robertson pupil

Bell’s Palsy

Bell’s palsy, or idiopathic facial nerve palsy, refers to the isolated paralysis of the facial muscles on one or both sides. It is of unclear cause, though damage to the seventh cranial, or FACIAL NERVE, possibly of viral origin, is thought likely. Occurring in both sexes at any age, it presents with a facial pain on the affected side, followed by an inability to close the eye or smile. The mouth appears to be drawn over to the opposite side, and ?uids may escape from the angle of the mouth. Lines of expression are ?attened and the patient is unable to wrinkle the brow. Rare causes include mastoiditis, LYME DISEASE, and hypertension.

Treatment Oral steroids, if started early, increase the rate of recovery, which occurs in over 90 per cent of patients, usually starting after two or three weeks and complete within three months. Permanent loss of function with facial contractures occurs in about 5 per cent of patients. Recurrence of Bell’s palsy is unusual.... bell’s palsy

Central Venous Pressure

The pressure of blood within the right atrium of the HEART as measured by a catheter and manometer.... central venous pressure

Breech Presentation

By the 32nd week of pregnancy most babies are in a head-down position in the womb. Up to 4 per cent of them, however, have their buttocks (breech) presenting at the neck of the womb. If the baby is still a breech presentation at the 34th to 35th week the obstetrician may, by external manipulation, try to turn it to the head-down position. If this is not successful, the fetus is left in the breech position. Breech deliveries are more di?cult for mother and baby because the buttocks are less e?cient than the head at dilating the cervix and vagina. An EPISIOTOMY is usually necessary to assist delivery, and obstetric FORCEPS may also have to be applied to the baby’s head. If the infant and/or the mother become unduly distressed, the obstetrician may decide to deliver the baby by CAESAREAN SECTION; some obstetricians prefer to deliver most breech-presentation babies using this method. (See PREGNANCY AND LABOUR.)... breech presentation

Bryophyllum Pinnatum

(Lam.) Kurz. 103 stearic, palmitic, myristic, oleic and Bryonopsis laciniosa

(Linn.) Naud.

Synonym: Bryonia laciniosa Linn. Diplocyclos palmatus Jeff.

Family: Cucurbitaceae.

Habitat: Throughout India.

English: Bryony.

Ayurvedic: Lingini, Shivalingi, Chitraphalaa.

Siddha/Tamil: Iyaveli, Iyaviraali.

Folk: Lingadonda (Telugu).

Action: Seeds—anti-inflammatory, spasmolytic. Used for vaginal dysfunctions, as a fertility promoting drug. Powdered seeds, also roots, are given to help conception in women. Plant is also used in venereal diseases.... bryophyllum pinnatum

Cadmium Poisoning

Cadmium poisoning is a recognised hazard in certain industrial processes, such as the manufacture of alloys, cadmium plating and glass blowing. Sewage sludge, which is used as fertiliser, may be contaminated by cadmium from industrial sources; such cadmium could be taken up into vegetable crops and cadmium levels in sewage are carefully monitored.

A tin-like metal, cadmium accumulates in the body. Long-term exposure can lead to EMPHYSEMA, renal failure (see KIDNEYS, DISEASES OF) and urinary-tract CALCULI. Acute exposure causes GASTROENTERITIS and PNEUMONITIS. Cadmium contamination of food is the most likely source of poisoning. The EU Directive on the Quality of Water for Human Consumption lays down 5 milligrams per litre as the upper safe level.... cadmium poisoning

Cleft Palate

A ?ssure in the roof of the mouth (palate) and/ or the lip which is present at birth. It is found in varying degrees of severity in about one in 700 children. Modern plastic surgery can greatly improve the functioning of lips and palate and the appearance of the baby. Further cosmetic surgery later may not be necessary. The parent of the child who has cleft lip and/ or palate will be given detailed advice speci?c to his or her case. In general the team of specialists involved are the paediatrician, plastic surgeon, dentist or orthodontic specialist, and speech therapist. (See PALATE, MALFORMATIONS OF.)... cleft palate

Community Paediatrician

Formerly entitled consultant paediatrician (community child health), these are specialists dealing with children with chronic problems not involving acute or hospital care. For example, they have a primary role in dealing with disabled children, children with special educational needs and abused children.... community paediatrician

Continuous Positive Airways Pressure

A method for treating babies who suffer from alveolar collapse in the lung as a result of HYALINE MEMBRANE DISEASE (see also RESPIRATORY DISTRESS SYNDROME).... continuous positive airways pressure

Crutch Palsy

Crutch palsy is weakness or paralysis of muscles in the wrist and hand, due to pressure exerted by the CRUTCH head on the nerves that control the affected muscles. It usually occurs because the crutch is too long for the individual, and/or if he or she attempts too much walking. The nerve damage is temporary and symptoms disappear if the crutch is properly used or left aside for a time.... crutch palsy

Dreams

See SLEEP.... dreams

False Positive

A positive test result for a condition that is not, in fact, present.... false positive

Fibrocystic Disease Of The Pancreas

See CYSTIC FIBROSIS.... fibrocystic disease of the pancreas

General Practice

A form of practice in which medical practitioners provide a wide range of primary health care services to people.... general practice

Gram-positive/negative

Gram’s Method is a staining procedure that separates bacteria into those that stain (positive) and those that don’t (negative). Gram-positive bugs cause such lovely things as scarlet fever, tetanus, and anthrax, while some of the gram negs can give you cholera, plague, and the clap. This is significant to the microbiologist and the pathologist; otherwise I wouldn’t worry. Still, knowing the specifics (toss in anaerobes and aerobes as well), you can impress real medical professionals with your knowledge of the secret, arcane language of medicine.... gram-positive/negative

Group Practice

A formal association of three or more health practitioners or other health professionals providing health services. Income from the practice is pooled and redistributed to the members of the group according to some prearranged plan.... group practice

Helicobacter Pylori

A bacterium which colonises the stomach. While it may cause no disease, it has a tendency to produce in?ammation – gastritis. This may progress in some people to peptic ulceration (see PEPTIC ULCER), and even to gastric cancer. The bacterium can be identi?ed on blood testing or, more accurately, by obtaining a biopsy of the stomach wall by ENDOSCOPY. It can be eradicated by treatment with PROTON-PUMP INHIBITORS and antibiotics.... helicobacter pylori

Latent Period

The time between initiation of infection and the first shedding of the agent.... latent period

Fungus Poisoning

Around 2,000 mushrooms (toadstools) grow in England, of which 200 are edible and a dozen are classi?ed as poisonous. Not all the poisonous ones are dangerous. It is obviously better to prevent mushroom poisoning by ensuring correct identi?cation of those that are edible; books and charts are available. If in doubt, do not eat a fungus.

Severe poisoning from ingestion of fungi is very rare, since relatively few species are highly toxic and most species do not contain toxic compounds. The most toxic species are those containing amatoxins such as death cap (Amanita phalloides); this species alone is responsible for about 90 per cent of all mushroom-related deaths. There is a latent period of six hours or more between ingestion and the onset of clinical effects with these more toxic species. The small intestine, LIVER and KIDNEYS may be damaged – therefore, any patient with gastrointestinal effects thought to be due to ingestion of a mushroom should be referred immediately to hospital where GASTRIC LAVAGE and treatment with activated charcoal can be carried out, along with parenteral ?uids and haemodialysis if the victim is severely ill. In most cases where effects occur, these are early-onset gastrointestinal effects due to ingestion of mushrooms containing gastrointestinal irritants.

Muscarine is the poisonous constituent of some species. Within two hours of ingestion, the victim starts salivating and sweating, has visual disturbances, vomiting, stomach cramps, diarrhoea, vertigo, confusion, hallucinations and coma, the severity of symptoms depending on the amount eaten and type of mushroom. Most people recover in 24 hours, with treatment.

‘Magic’ mushrooms are a variety that contains psilocybin, a hallucinogenic substance. Children who take such mushrooms may develop a high fever and need medical care. In adults the symptoms usually disappear within six hours.

Treatment If possible, early gastric lavage should be carried out in all cases of suspected poisoning. Identi?cation of the mushroom species is a valuable guide to treatment. For muscarine poisoning, ATROPINE is a speci?c antidote. As stated above, hospital referral is advisable for people who have ingested poisonous fungi.... fungus poisoning

Mastoid Process

The large process of the temporal bone of the SKULL which can be felt immediately behind the ear. It contains numerous cavities, one of which – the mastoid antrum – communicates with the middle ear, and is liable to suppurate when the middle ear is diseased. (See under EAR, DISEASES OF.)... mastoid process

Meralgia Paraesthetica

A condition characterised by pain and PARAESTHESIA on the front and outer aspect of the thigh. It is more common in men than in women, and the victims are usually middle-aged, overweight and out of condition. It is due to compression of the lateral cutaneous nerve of the thigh, and exacerbated by an uncomfortable driving position when motoring long distances. Reduction in weight, improvement in general ?tness and correction of faulty posture usually bring relief. If these fail, surgical decompression of the nerve may help.... meralgia paraesthetica

Morning-after Pill

See CONTRACEPTION.... morning-after pill

Muira Puama

Muira puama is one of the most popular and widely consumed herbs. It grows in the northern Amazon river basin. This herb has been used to enhance libido for a long time, making the harvest and sale of the herb a large business throughout Brazil.... muira puama

Multiple Personality Disorder

The individual with this psychiatric disorder has two or more di?erent personalities, often contrasting. The dominant personality at the time determines the behaviour and attitude of the individual, who customarily seems not to know about the other personality – or personalities. The switch from one personality to another is abrupt and the mental condition of the di?ering personalities is usually normal. It is possible that child abuse is a factor in the disorder, which is treated by psychotherapy. The classic multiple personality was the ?ctional form of Dr Jekyll and Mr Hyde.... multiple personality disorder

Olecranon Process

The large process on the ulnar bone that projects behind the joint of the elbow.... olecranon process

Pacinian Corpuscles

Pacinian corpuscles, or lamellated corpuscles, are minute bulbs at the ends of the nerves scattered through the SKIN and subcutaneous tissue, and forming one of the end-organs for sensation.... pacinian corpuscles

Packed Cell Volume

That fraction of the blood’s total volume made up of red cells. The packed cell volume is found by centrifuging blood in a tube and measuring the depth of the column of red cells as a fraction of the whole column of blood. (See also HAEMATOCRIT.)... packed cell volume

Pacs

See PICTURE ARCHIVING AND COMMUNICATIONS SYSTEM (PACS).... pacs

Palilalia

Also called paliphrasia, this means the involuntary repetition of words or sentences. It is a symptom of GILLES DE LA TOURETTE’S SYNDROME.... palilalia

Palindromic

An adjective describing symptoms or diseases that recur. For example, palindromic rheumatoid arthritis is a condition in which symptoms wax and wane with periods of complete remission.... palindromic

Palliative

A term applied to treatment that eases the symptoms of a disorder rather than curing the condition. (See also HOSPICE; PALLIATIVE CARE.)... palliative

Palliative Care

The active total care offered to a person and that person’s family when it is recognized that the illness is no longer curable, in order to concentrate on the person’s quality of life and the alleviation of distressing symptoms. The focus of palliative care is neither to hasten nor postpone death. It provides relief from pain and other distressing symptoms and integrates the psychological and spiritual aspects of care. It offers a support system to help relatives and friends cope during an individual’s illness and with their bereavement.... palliative care

Pallidotomy

Also known as pallidectomy, this is a neurosurgical procedure in which the activities of the globus pallidus area of the BRAIN are destroyed or modi?ed. The operation is sometimes used to relieve the symptoms of PARKINSONISM and other neurological conditions in which involuntary movements are a signi?cant and disabling symptom.... pallidotomy

Palpebral

Relating to the eyelid (see EYE).... palpebral

Pacemaker

A cardiac or arti?cial pacemaker is a device that helps a faulty HEART to maintain normal rhythm. It consists of a battery that stimulates the heart by an electric current passed through an insulated wire which is attached either to the surface of the ventricle (epicardial pacemaker) or to the heart lining (endocardial pacemaker). In a normal heart, the regular electrical impulses are initiated by a special area of tissue (sinoatrial node). A cardiac pacemaker is used when a person’s sinoatrial node is malfunctioning or when there is interference with the passage of normal impulses. Some devices send out signals at a ?xed rate; others monitor the rate and, when it falters in any way, stimulate regular contractions. Implantation is carried out under a local anaesthetic, and the lithium batteries can last for several years. People with pacemakers should avoid any source of powerful electromagnetic radiation – radio or radar transmitters or airport security screens. (See also CARDIAC PACEMAKER.)... pacemaker

Paedophilia

A perverse sexual attraction to children of either sex. Paedophiles are nearly always male and may have heterosexual, homosexual or bisexual orientation.

In England and Wales, the age of consent for heterosexual and homosexual sex is 16 years; in Northern Ireland, 17 years; and in Scotland the age of consent for heterosexual sex is 12 for a girl and 14 for a boy. However, girls are protected by Section 5 of the Criminal Law (Consolidation) Act 1995 which makes it an o?ence to have sexual intercourse with a girl aged under

16. For girls under 13, the maximum sentence is life-imprisonment, and between 13 and 16, two years’ imprisonment. Homosexual consent in Scotland is 16.

Paedophiles suffer from personality problems rather than overt psychoses (see PSYCHOSIS) and the origins of their behaviour may lie in their own early sexual experiences. Their behaviour often has features of an addiction.

It is of note that most underaged sex is between family members such as stepfather and daughter rather than with a stranger or predatory paedophile.

(See CHILD ABUSE.)... paedophilia

Pancarditis

In?ammation of the pericardium, myocardium, and endocardium at the same time (see HEART – Structure).... pancarditis

Pancytopenia

A fall in the number of red ERYTHROCYTES and white LEUCOCYTES, as well as of platelets (see BLOOD – Composition). The condition is found in aplastic ANAEMIA, tumours of the BONE MARROW, enlarged SPLEEN, and other disorders.... pancytopenia

Panniculitis

In?ammation of the subcutaneous fat (see FAT – Body fat). It may occur anywhere on the body surface.... panniculitis

Pannus

1) Blood vessels growing into the cornea (see EYE) beneath its epithelium. Seen in TRACHOMA and to a lesser extent in patients who are long-term soft-contact-lens wearers. 2) In?ammatory tissue which replaces CARTILAGE in RHEUMATOID ARTHRITIS.... pannus

Pansy

(English) As delicate as a flower; a thoughtful girl

Pansey, Pansi, Pansie, Pansee, Panzi, Panzy, Panzie, Panzee, Pansea, Panzea... pansy

Papanicolaou Test

See CERVICAL SMEAR.... papanicolaou test

Papaverine

A smooth-muscle (see MUSCLE) relaxant once used to treat IMPOTENCE (erectile dysfunction). The drug is injected directly into the corpora caverosa (spongy, blood-?lled erectile tissue) of the PENIS. Men with psychogenic or neurological impotence may respond to this treatment. Its use is less common since SILDENAFIL (Viagra®) was introduced for the treatment of erectile dysfunction.... papaverine

Papillitis

In?ammation of any PAPILLA, but especially of the prominence formed by the end of the optic nerve in the retina (see EYE) – also known as OPTIC NEURITIS.... papillitis

Papina

(Native American) Resembling ivy Papinah, Papyna, Papena, Papeena, Papiena, Papeina, Papeana... papina

Paradoxical Breathing

The reverse of the normal movements of breathing (see RESPIRATION). The chest wall moves in instead of out when breathing in (inspiration), and out instead of in when breathing out (expiration). The spaces between the ribs are indrawn on inspiration – a symptom seen in children with respiratory distress, say, as a result of ASTHMA or lung infections. Patients with CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) often suffer from paradoxical breathing; and trauma to the rib cage, with fractured sternum and ribs, also cause the condition. Treatment is of the underlying cause.... paradoxical breathing

Paraganglion

One of the small ovoid collections of cells occurring in the walls of the ganglia of the SYMPATHETIC NERVOUS SYSTEM adjacent to the SPINAL CORD. They are CHROMAFFIN cells and sometimes secrete ADRENALINE.... paraganglion

Paragonimiasis

A tropical disease found mainly in the Far East. It is caused by infections of the lungs by a parasitic ?uke called Paragonimus westermani. The infection is acquired by eating insu?ciently cooked shell?sh. The affected person has symptoms similar to those of chronic BRONCHITIS; treatment is with the drugs CHLOROQUINE and bithionol.... paragonimiasis

Paraldehyde

A clear, colourless liquid with a penetrating ethereal (see ETHER) odour, paraldehyde may be given by mouth, rectally, or occasionally in intramuscular injection. The drug’s prime use is as a hypnotic (see HYPNOTICS) in mentally unstable patients. It is also indicated as an anticonvulsant in STATUS EPILEPTICUS (after initial intravenous DIAZEPAM) and in TETANUS. Its unpleasant taste restricts its use, but this has the advantage that it usually prevents the patient from becoming an addict.

Caution is needed when treating patients with bronchopulmonary disease or liver impairment; and intramuscular injection near the sciatic nerve should be avoided, as it may cause severe CAUSALGIA. Adverse effects include rashes; pain and sterile ABSCESS after intramuscular injection; rectal irritation after ENEMA.... paraldehyde

Paramedical

A generic title for the professions which work closely with or are reponsible to the medical profession in caring for patients. A paramedical worker, coloquially called a ‘paramedic’, has skills, experience and quali?cations in certain spheres of health care. Examples are ambulance crew – primarily those trained to deal with emergencies; physiotherapists (see PHYSIOTHERAPY); radiographers (see RADIOGRAPHER); and dieticians (see DIETETICS).... paramedical

Parameter

A measurement of a certain factor – for example, pulse rate, blood pressure, or haemoglobin concentration – that is relevant to a disorder under investigation. Often wrongly used to describe the range of test results.... parameter

Paramnesia

A derangement of the MEMORY in which words are used without a comprehension of their meaning; it is also applied to illusions of memory in which a person in good faith imagines and describes experiences which never occurred to him or her.... paramnesia

Paraphasia

Misplacement of words, or use of wrong words, in speech as a result of a lesion in the speech region of the BRAIN.... paraphasia

Paraphrenia

A form of PARANOIA. (See also MENTAL ILLNESS.)... paraphrenia

Parasuicide

Non-fatal self-poisoning or self-injury, or attempted suicide. It is most common in the 12–15 age group. As a rule, the intention is not to commit suicide but to sound a cry for help to resolve an acute domestic, social or personal upset.... parasuicide

Paratyphoid Fever

See ENTERIC FEVER.... paratyphoid fever

Parenchyma

A term meaning originally all the soft tissues of internal organs except their supporting structures, although now reserved for the secreting cells of the glandular organs.... parenchyma

Parenteral

Administration of drugs by any route other than by the mouth or by the bowel – for example, by intramuscular or intravenous injection or infusion.... parenteral

Parasympathetic Nervous System

That part of the AUTONOMIC NERVOUS SYSTEM which is connected with the BRAIN and SPINAL CORD through certain nerve centres in the midbrain, medulla, and lower end of the cord. The nerves from these centres are carried in the third, seventh, ninth and tenth cranial nerves and the second, third and fourth sacral nerves. The action of the parasympathetic system is usually antagonistic to that of the sympathetic system. Thus it inhibits the action of the HEART and augments the action of the INTESTINE; whereas the sympathetic augments the action of the heart and inhibits that of the intestine. (See diagram of sympathetic and parasympathetic nervous systems under NERVOUS SYSTEM.)... parasympathetic nervous system

Parietal Bone

Either one of a pair of bones that form the top and sides of the cranium of the SKULL.... parietal bone

Parietal Lobe

A major section of each cerebral hemisphere (see BRAIN). The two lobes lie under the parietal bones and contain the sensory cortex.... parietal lobe

Parosmia

A perverted sense of SMELL; everything may smell unpleasant to the affected individual. The most common cause is some septic condition of the nasal passages (see NOSE), but the condition may occasionally be due to a lesion in the BRAIN involving the centre responsible for the sense of smell.... parosmia

Parotid Gland

One of the SALIVARY GLANDS. It is situated just in front of the ear, and its duct runs forwards across the cheek to open into the interior of the mouth on a little projection opposite the second last tooth of the upper row. The parotid gland is generally the ?rst of the salivary glands to become enlarged in MUMPS.... parotid gland

Parrot Disease

See PSITTACOSIS.... parrot disease

Parthenogenesis

Non-sexual reproduction. In other words, development of the OVUM into an individual without fertilisation by a SPERMATOZOON. It is common in plants and has been produced in animals experimentally.... parthenogenesis

Partogram

A method of recording the degree of dilatation, or opening, of the cervix (or neck) of the UTERUS in labour (see PREGNANCY AND LABOUR) to assess how labour is progressing.... partogram

Passive Movement

A movement induced by someone other than the patient. Physiotherapists (see PHYSIOTHERAPY) manipulate joints by passive movement in order to retain and encourage function of a nerve or muscle that is not working normally because of injury or disease.... passive movement

Pasteurella

A group of bacilli. They are essentially animal parasites (see PARASITE) that under certain conditions are transmitted to humans, and include the micro-organism responsible for PLAGUE and TULARAEMIA.... pasteurella

Patent

In the medical context, a term meaning open – for example, patent DUCTUS ARTERIOSUS. The term is also used for proprietary MEDICINES which, because of the research and cost involved in producing many of them, are protected by a patent. This means that without an agreement, no company or organisation other than the patent-holder can produce the substance.... patent

Patho

A pre?x indicating relationship to a disease – for example, PATHOLOGY, a study of disease.... patho

Pathogenesis

The ways in which a disease or disorder starts and develops. The term applies in particular to the physiological and cellular activities that are involved in the mode of origin and development of the condition.... pathogenesis

Patia

(Latin) An open-minded woman... patia

Patient

A person in contact with the health system seeking attention for a health condition.... patient

Peak Flow Meter

A device that measures the rate at which an individual can expel air from the LUNGS. This is an indication of the reserve in the capacity of the lungs. Narrowed airways (bronchospasm) slow the rate at which air can be expelled; the peak ?ow meter can assess the severity of the condition. ASTHMA causes bronchospasm and the device can measure the e?ectiveness of treatment with BRONCHODILATOR drugs; this should be done regularly to monitor the progress of the disease.... peak flow meter

Pectoriloquy

The resonance of the voice, when spoken or whispered words can be clearly heard through the stethoscope placed on the chest wall. It is a sign of consolidation, or of a cavity, in the lung.... pectoriloquy

Pedicle

A narrow tube of tissue formed by folded skin which links a piece of tissue used for surgical grafting to its site of origin. A pedicle graft is used by the surgeon – usually a reconstructive/ plastic surgeon – when the site under repair is unsuitable for an independent graft, usually because the blood supply at the recipient site is inadequate. (See RECONSTRUCTIVE (PLASTIC) SURGERY.)

A pedicle is also found occurring between a tumour and its tissue of origin, and the term is used in anatomy to refer to any slim tubular process.... pedicle

Penia

(Greek) In mythology, the personification of poverty

Peniah, Penea, Peniya, Peneah, Peniyah... penia

Penicillinase

A bacterial ENZYME capable of neutralising the antibacterial properties of PENICILLIN and other beta-lactam antibiotics such as the CEPHALOSPORINS. Most staphylococci are now resistant to benzylpenicillin because they produce this enzyme; cloxacillin, ?ucloxacillin and temocillin are not inactivated.... penicillinase

Penicillin

The name given by Sir Alexander Fleming, in 1929, to an antibacterial substance produced by the mould Penicillium notatum. The story of penicillin is one of the most dramatic in the history of medicine, and its introduction into medicine initiated a new era in therapeutics comparable only to the introduction of ANAESTHESIA by Morton and Simpson and of ANTISEPTICS by Pasteur and Lister. The two great advantages of penicillin are that it is active against a large range of bacteria and that, even in large doses, it is non-toxic. Penicillin di?uses well into body tissues and ?uids and is excreted in the urine, but it penetrates poorly into the cerebrospinal ?uid.

Penicillin is a beta-lactam antibiotic, one of a group of drugs that also includes CEPHALOSPORINS. Drugs of this group have a four-part beta-lactam ring in their molecular structure and they act by interfering with the cell-wall growth of mutliplying bacteria.

Among the organisms to which it has been, and often still is, active are: streptococcus, pneumococcus, meningococcus, gonococcus, and the organisms responsible for syphilis and for gas gangrene (for more information on these organisms and the diseases they cause, refer to the separate dictionary entries). Most bacteria of the genus staphylococcus are now resistant because they produce an enzyme called PENICILLINASE that destroys the antibiotic. A particular problem has been the evolution of strains resistant to methicillin – a derivative originally designed to conquer the resistance problem. These bacteria, known as METHICILLINRESISTANT STAPHYLOCOCCUS AUREUS (MRSA), are an increasing problem, especially after major surgery. Some are also resistant to other antibiotics such as vancomycin.

An important side-e?ect of penicillins is hypersensitivity which causes rashes and sometimes ANAPHYLAXIS, which can be fatal.

Forms of penicillin These include the following broad groups: benzylpenicillin and phenoxymethyl-penicillin; penicillinase-resistant penicillins; broad-spectrum penicillins; antipseudomonal penicillins; and mecillinams. BENZYLPENICILLIN is given intramuscularly, and is the form that is used when a rapid action is required. PHENOXYMETHYLPENICILLIN (also called penicillin V) is given by mouth and used in treating such disorders as TONSILLITIS. AMPICILLIN, a broad-spectrum antibiotic, is another of the penicillins derived by semi-synthesis from the penicillin nucleus. It, too, is active when taken by mouth, but its special feature is that it is active against gram-negative (see GRAM’S STAIN) micro-organisms such as E. coli and the salmonellae. It has been superceded by amoxicillin to the extent that prescriptions for ampicillin written by GPs in the UK to be dispensed to children have fallen by 95 per cent in the last ten years. CARBENICILLIN, a semi-synthetic penicillin, this must be given by injection, which may be painful. Its main use is in dealing with infections due to Pseudomonas pyocanea. It is the only penicillin active against this micro-organism which can be better dealt with by certain non-penicillin antibiotics. PIPERACILLIN AND TICARCILLIN are carboxypenicillins used to treat infections caused by Pseudomonas aeruginosa and Proteus spp. FLUCLOXACILLIN, also a semi-synthetic penicillin, is active against penicillin-resistant staphylococci and has the practical advantage of being active when taken by mouth. TEMOCILLIN is another penicillinase-resistant penicillin, e?ective against most gram-negative bacteria. AMOXICILLIN is an oral semi-synthetic penicillin with the same range of action as ampicillin but less likely to cause side-effects. MECILLINAM is of value in the treatment of infections with salmonellae (see FOOD POISONING), including typhoid fever, and with E. coli (see ESCHERICHIA). It is given by injection. There is a derivative, pivmecillinam, which can be taken by mouth. TICARCILLIN is a carboxypenicillin used mainly for serious infections caused by Pseudomonas aeruginosa, though it is also active against some gram-negative bacilli. Ticarcillin is available only in combination with clarulanic acid.... penicillin

Pepper

(American) Resembling the pepper plant; flavorful Peper... pepper

Pepsin

An ENZYME found in the gastric juice which digests proteins, converting them into peptides (see PEPTIDE) and AMINO ACIDS. It is used in the preparation of predigested foods (PEPTONISED FOODS), or, more frequently, taken orally after meals. Available as a white powder or liquid, it is prepared from the mucous membrane of cow, sheep, or pig stomachs.... pepsin

Peppermint

Mentha piperita. N.O. Labiateae.

Synonym: Balm Mint, Brandy Mint.

Habitat: Damp places by water courses. Largely cultivated, especially in the U.S.A., for its oil, which is probably the most used of all the volatile oils. Features ? Stem quadrangular, purplish, reaching three or four feet high. Leaves stalked, serrate, very slightly hairy, about two and a half inches by one inch.

Characteristic taste and smell. Part used ? Herb.

Action: Carminative, stomachic, stimulant.

In flatulence, colic and nausea. Usually combined with other remedies when a complete stomachic is needed. Particularly suitable for children. Dose, wineglassful of ounce to pint infusion.... peppermint

Percutaneous Transluminal Coronary Angioplasty

A treatment for a stenosed (restricted) coronary artery (see ARTERIES). A balloon-tipped catheter (see CATHETERS) is passed through an incision in the skin of the chest into the artery of the HEART that has developed stenosis (narrowing). The balloon is aligned with the stenosed section and then in?ated to dilate the coronary artery and allow the blood to ?ow more freely.... percutaneous transluminal coronary angioplasty

Perfusion

The transfer of ?uid through a tissue. For example, when blood passes through the lung tissue, dissolved oxygen perfuses from the moist air in the alveoli to the blood. Fluid may also be deliberately introduced into a tissue by injecting it into the blood vessels supplying the tissue. It is used as a sign of how adequate the circulation is at the time of illness. Poor peripheral perfusion, a sign of circulatory collapse or shock, is recognised by pressing on the skin to force blood from capillaries. The time it takes for them to re?ll and the skin to become pink is noted: more than 5 seconds, and the circulation is likely to be compromised.... perfusion

Periarteritis Nodosa

See POLYARTERITIS NODOSA.... periarteritis nodosa

Perichondritis

In?ammation of CARTILAGE and the tissue surrounding it, usually as a result of chronic infection.... perichondritis

Perimetritis

A localised in?ammation of the PERITONEUM surrounding the UTERUS.... perimetritis

Perimetry

A test of the visual ?elds of the EYE that assesses the extent of peripheral vision. The procedure does not normally form part of a routine test of vision but can be of value in assessing neurological diseases such as tumour of the brain.... perimetry

Periodicity

Recurrence at regular intervals of symptoms in malaria, characterised clinically by paroxysms and resulting from the invasion of the blood by new generations of parasites. Periodicity may be quotidian, tertian, quartan or double quartan according to the intervals between paroxysms.... periodicity

Periodontal

An adjective that relates to the tissues around the TEETH.... periodontal

Periodontal Membrane

See TEETH.... periodontal membrane

Periodontitis

see PYORRHEA... periodontitis

Peripheral Vascular Disease

The narrowing of the blood vessels in the legs and, less commonly, in the arms. Blood ?ow is restricted, with pain occurring in the affected area. If the blood supply is seriously reduced, GANGRENE of the tissues supplied by the affected vessel(s) may occur and the limb may need to be amputated. The common cause is ATHEROSCLEROSIS which may be brought on by HYPERTENSION, excessively fatty diet, poorly controlled DIABETES MELLITUS or smoking – the latter being the biggest risk factor, with 90 per cent of affected patients having been moderate to heavy smokers. Stopping smoking is essential; adequate exercise and a low-fat diet are important measures. Surgery may be required.... peripheral vascular disease

Perla

(Latin) An important woman Perlah... perla

Peroneal

The name given to structures, such as the muscles, and nerves, on the outer or ?bular side of the leg.... peroneal

Perseveration

Perseveration is the senseless repetition of words or deeds by a person with a disordered mind.... perseveration

Persimmon

Diospyros virginiana and other species

Description: These trees have alternate, dark green, elliptic leaves with entire margins. The flowers are inconspicuous. The fruits are orange, have a sticky consistency, and have several seeds.

Habitat and Distribution: The persimmon is a common forest margin tree. It is wide spread in Africa, eastern North America, and the Far East.

Edible Parts: The leaves are a good source of vitamin C. The fruits are edible raw or baked. To make tea, dry the leaves and soak them in hot water. You can eat the roasted seeds.

CAUTION

Some persons are unable to digest persimmon pulp. Unripe persimmons are highly astringent and inedible.... persimmon

Personality Disorder

Condition in which the individual fails to learn from experience or to adapt to changes. The outcome is impaired social functioning and personal distress. There are three broad overlapping groups. One group is characterised by eccentric behaviour with paranoid or schizoid overtones. The second group shows dramatic and emotional behaviour with self-centredness and antisocial behaviour as typical components of the disorder. In the third group, anxiety and fear are the main characteristics, which are accompanied by dependency and compulsive behaviour. These disorders are not classed as illnesses but psychotherapy and behavioural therapy may help. The individuals affected are notoriously resistant to any help that is o?ered, tending to blame other people, circumstances or bad luck for their persistent diffculties. (See MENTAL ILLNESS; MULTIPLE PERSONALITY DISORDER; MUNCHAUSEN’S SYNDROME.)... personality disorder

Perthes’ Disease

A condition of the hip in children, due to death and fragmentation of the epiphysis (or spongy extremity) of the head of the femur. The cause is not known. The disease occurs in the 4–10 year age-group, with a peak between the ages of six and eight; it is ten times more common in boys than girls, and is bilateral in 10 per cent of cases. The initial sign is a lurching gait with a limp, accompanied by pain. Treatment consists of limiting aggressive sporting activity which may cause intact overlying CARTILAGE to loosen. Where there are no mechanical symptoms and MRI scanning shows that the cartilage is intact, only minor activity modi?cation may be necesssary – but for several months or even years. Any breach in the cartilage is dealt with at ARTHROSCOPY by ?xing or trimming any loose ?aps. Eventually the disease burns itself out.... perthes’ disease

Pes Planus

The technical name for FLAT-FOOT.... pes planus

Pesticides

Any substance or mixture of substances intended for preventing or controlling unwanted species of plants and animals. This includes any substances intended for use as plant-growth regulators, defoliants or desiccants. The main groups of pesticides are: herbicides to control weeds; insecticides to control insects; and fungicides to control or prevent fungal disease.... pesticides

Petiole

A leafstalk or stem, or an unexpanded section.... petiole

Peyer’s Patches

Group of lymphoid tissue in the small intestine, especially involved in typhoid infections.... peyer’s patches

Pharmacogenomics

Also called pharmacogenetics – the use of human genetic variations to optimise the discovery and development of drugs and the treatment of patients. The human race varies much more in its genetic make-up than has previously been realised; these variations in GENES and their PROTEIN products could be utilised to provide safer and more e?ective drugs. Genes affect drug absorption, distribution, METABOLISM and excretion. Drugs are designed and prescribed on the basis of a population’s needs, but patients comprise a diverse range of individuals. For example, nearly one-third of patients fail to respond to the cholesterol-reducing group of drugs, the STATINS. Around half do not respond to the tricyclic ANTIDEPRESSANT DRUGS. Over 80 per cent of patients’ responses to drugs depends on their genetics: this genetic variation needs to be identi?ed so as to make the prescription of drugs more e?ective, and technology for analysing genetic variants is progressing. Assessing drug e?ectiveness, however, is not simple because the health and diets of individuals are di?erent and this can affect the response to a drug. Even so, the genetic identi?cation of people who would or would not respond to a particular drug should bene?t patients by ensuring a more accurately targeted drug and by reducing the risks to a person of side-effects from taking a drug that would not work. There would also be substantial economic savings.... pharmacogenomics

Phenol

Another name for CARBOLIC ACID.... phenol

Phenotype

An individual’s characteristics as determined by the interaction between his or her genotype – quota of GENES – and the environment.... phenotype

Phenoxybenzamine

An alpha-adrenoceptor blocking drug (see ADRENERGIC RECEPTORS) used in the treatment of HYPERTENSION caused by PHAEOCHROMOCYTOMA.... phenoxybenzamine

Phenylalanine

A natural amino acid (see AMINO ACIDS) essential for growth in infants, and for nitrogen metabolism in adults.... phenylalanine

Phenindione

A synthetic anticoagulant (see ANTICOAGULANTS). Given by mouth, it is used to prevent the formation of clots in the blood in rheumatic heart disease and atrial ?brillation (see HEART, DISEASES OF); as prophylaxis after insertion of a prosthetic heart valve; and as prophylaxis and treatment of venous thrombosis and pulmonary embolism. It is slower in action than WARFARIN, not achieving its full anticoagulant e?ect until up to 48 hours after the initial dose. The drug should be avoided in patients with renal or hepatic impairment, and whenever severe hypersensitivity reactions have previously occurred. Adverse effects include rashes, fever, LEUCOPENIA, AGRANULOCYTOSIS, diarrhoea and pink urine; breast feeding should be avoided.... phenindione

Phenothiazines

A group of major antipsychotic drugs, colloquially called ‘TRANQUILLISERS’, widely used to treat psychoses (see PSYCHOSIS). They can be divided into three main groups. Chlorpromazine, methotrimeprazine and promazine are examples of group 1, usually characterised by their sedative effects and moderate antimuscarinic and extrapyramidal side-effects. Group 2 includes pericyazine, pipothiazine and thioridazine, which have moderate sedative effects but signi?cant antimuscarinic action and modest extrapyramidal side-effects. Fluphenazine, perphenazine, prochlorperazine and tri?uoperazine comprise group 3. Their sedative effects are less than for the other groups and they have little antimuscarinic action; they have marked extrapyramidal side-effects.

Uses Phenothiazines should be prescribed and used with care. The drugs di?er in predominant actions and side-effects; selection depends on the extent of sedation required and the susceptibility of the patient to extrapyramidal side-effects. The di?erences between the drugs, however, are less important than the variabilities in patients’ responses. Patients should not be prescribed more than one antipsychotic drug at a time. In the short term these therapeutically powerful drugs can be used to calm disturbed patients, whatever the underlying condition (which might have a physical or psychiatric basis). They also alleviate acute anxiety and some have antidepressant properties, while others worsen DEPRESSION (see also MENTAL ILLNESS).... phenothiazines

Phlebolith

The term applied to a small stone formed in a vein (see VEINS) as a result of calci?cation of a THROMBUS.... phlebolith

Phonation

The production of vocal sounds – in particular, speech.... phonation

Phosphates

Salts of phosphoric acid. As this substance is contained in many articles of food as well as in bone, the nuclei of cells, and the nervous system, phosphates are constantly excreted in the URINE. The continued use of an excess of food containing alkalis, such as green vegetables, and still more the presence in the urine of bacteria which lead to its decomposition, produce the necessary change from the natural mild acidity to alkalinity, and lead to the deposit of phosphates and to their collection into stones.... phosphates

Phospholipid

A LIPID, the molecule of which contains a chemical derivative of PHOSPHORUS called phosphate. This type of lipid, which includes cephalins, lecithins and plasmalogens, is found in all tissues and organs, especially the BRAIN. Phospholipids are produced in the LIVER and and take part in many of the body’s metabolic activities (see METABOLISM).... phospholipid

Photochemotherapy

A form of treatment in which deliberate exposure to a photosensitising drug and ultraviolet light bene?ts certain skin diseases, particularly PSORIASIS and T-cell LYMPHOMA. A psoralen is the photoactive agent which reacts with long-wave ultraviolet light (UVA), giving the acronym, PUVA therapy.... photochemotherapy

Photodynamic Therapy

This comprises a photosensitising agent (one activated by light), which accumulates in malignant tissue, and a source of light that activates the photosensitiser, triggering it to generate highly reactive oxygen compounds that destroy malignant cells. One such photosensitiser is temopor?n. Photodynamic therapy is used to treat various types of malignancy; a recognised complication is photosensitivity, when a patient may suffer burns after transient exposure to sunlight. Photodynamic therapy is increasingly used and photosensitivity reactions may also become more common.... photodynamic therapy

Photopsia

This is a description of the ?ashing lights which are a not uncommon AURA preceding an attack of MIGRAINE.... photopsia

Photosynthesis

The method by which green plants and some bacteria produce CARBOHYDRATE from water and carbon dioxide. They use energy absorbed from the sun’s rays by a green pigment in the organism called chlorophyll. Photosynthesis is one of the earth’s fundamental biological processes. As well as converting the carbon dioxide into the essential biological compound carbohydrate, the process removes the gas from the atmosphere where, if it builds to excess, the atmospheric temperature rises, thus contributing to global warming.... photosynthesis

Phrenic Nerve

The NERVE which chie?y supplies the DIAPHRAGM. A phrenic nerve arises on each side of the SPINAL CORD from the third, fourth and ?fth cervical spinal nerves; both follow a long course down the neck, and through the chest to the diaphragm. They play a key part in RESPIRATION through control of the diaphragm. Injury to one nerve paralyses one half of the diaphragm. Occasionally the phrenic nerve may be surgically crushed as part of the treatment to repair a HIATUS HERNIA or, rarely, to stop intractable hiccups.... phrenic nerve

Phrenology

A quack method, common in the Victorian era, allegedly to study the mind and character of individuals from the shape of the head. As the shape of the head has been shown to depend chie?y upon accidental characteristics, such as the size of the air spaces in the bones, and not upon development of special areas in the contained brain, there is no scienti?c basis for the practice.... phrenology

Phthisis

A historical term means wasting, and was applied to that progressive enfeeblement and loss of weight that arose from tuberculous disease of all kinds, but especially from the disease as it affected the lungs (see TUBERCULOSIS).... phthisis

Physical Examination

That part of a patient’s consultation with a doctor in which the doctor looks, feels (palpates) and listens to (auscultates) various parts of the patient’s body. Along with the history of the patient’s symptoms, this enables the doctor to assess the patient’s condition and decide whether an immediate diagnosis is possible or whether laboratory or imaging investigations are needed to reach a diagnosis. A full physical examination may take 30 minutes or more. Physical examination, along with certain standard investigations, is done when a person attends for a ‘preventive’ check-up of his or her state of health.... physical examination

Physical Medicine

A medical specialty founded in 1931 and recognised by the Royal College of Physicians of London in 1972. Physical-medicine specialists started by treating rheumatic diseases; subsequently their work developed to include the diagnosis and rehabilitation of people with physical handicaps. The specialty has now been combined with that of RHEUMATOLOGY. (See also PHYSIOTHERAPY.)... physical medicine

Physician

Professional person qualified by education and authorised by law to practise medicine. In certain countries refers to a specialist in internal medicine.... physician

Physostigmine

Also known as eserine. An alkaloid (see ALKALOIDS) obtained from Calabar bean, the seed of Physostigma venenosum, a climbing plant of West Africa. Its action depends on the presence of two alkaloids, the one known as physostigmine or eserine, the other as calabarine, the former of these being much the more important.

Action Physostigmine produces the same e?ect as stimulation of the PARASYMPATHETIC NERVOUS SYSTEM: i.e. it constricts the pupil of the eye, stimulates the gut, increases the secretion of saliva, stimulates the bladder, and increases the irritability of voluntary muscle. In poisonous doses it brings on a general paralysis.

Uses It is used in medicine in the form of eye drops or ointment to treat GLAUCOMA.... physostigmine

Pica

This is the Latin for magpie and is used to describe an abnormal craving for unusual foods. It is not uncommon in pregnancy. Among the unusual substances for which pregnant women have developed a craving are soap, clay pipes, bed linen, charcoal, ashes – and almost every imaginable food stu? taken in excess. In primitive races, the presence of pica is taken as an indication that the growing fetus requires such food. It is also not uncommon in children in whom, previously, it was an important cause of LEAD POISONING due to ingestion of paint ?akes. (See also APPETITE.)... pica

Picric Acid

A yellow crystalline solid substance which is used as a ?xative for tissues being prepared for examination under a microscope; it is also used as a dye.... picric acid

Pigment

The term applied to the colouring matter of various secretions, blood, etc.; also to any medicinal preparation of thick consistency intended for painting on the skin or mucous membranes.... pigment

Pili

(Egyptian) The second-born child Pilie, Pily, Piley, Pilee, Pilea, Pileigh... pili

Pineal Gland

A small reddish structure, 10 mm in length and shaped somewhat like a pine cone (hence its name), situated on the upper part of the midbrain (see BRAIN). Many theories have been expounded as to its function, but there is increasing evidence that, in some animals at least, it is affected by light and plays a part in hibernation and in controlling sexual activity and the colour of the skin. This it seems to do by means of a substance it produces known as MELATONIN. There is also growing evidence that it may play a part in controlling the circadian rhythms of the body – the natural variations in physiological activities throughout the 24-hour day.... pineal gland

Pineapple

See Piña.... pineapple

Pine

Pinus species

Description: Pine trees are easily recognized by their needlelike leaves grouped in bundles. Each bundle may contain one to five needles, the number varying among species. The tree’s odor and sticky sap provide a simple way to distinguish pines from similar looking trees with needlelike leaves.

Habitat and Distribution: Pines prefer open, sunny areas. They are found throughout North America, Central America, much of the Caribbean region, North Africa, the Middle East, Europe, and some places in Asia.

Edible Parts: The seeds of all species are edible. You can collect the young male cones, which grow only in the spring, as a survival food. Boil or bake the young cones. The bark of young twigs is edible. Peel off the bark of thin twigs. You can chew the juicy inner bark; it is rich in sugar and vitamins. Eat the seeds raw or cooked. Green pine needle tea is high in vitamin C. Other Uses : Use the resin to waterproof articles. Also use it as glue. Collect the resin from the tree. If there is not enough resin on the tree, cut a notch in the bark so more sap will seep out. Put the resin in a container and heat it. The hot resin is your glue. Use it as is or add a small amount of ash dust to strengthen it. Use it immediately. You can use hardened pine resin as an emergency dental filling.... pine

Pinnate

A compound leaf, having the leaflets arranged on each side of the stem.... pinnate

Pinworm

See ENTEROBIASIS.... pinworm

Piperazine

A drug used for the treatment of threadworms (see ENTEROBIASIS) and ASCARIASIS.... piperazine

Placenta Praevia

Implantation of the PLACENTA in the bottom part of the UTERUS adjacent to or over the CERVIX. The condition may cause few problems during pregnancy or labour; it may, however, cause vaginal bleeding late in pregnancy or hinder vaginal delivery of the baby and this may necessitate obstetric intervention.... placenta praevia

Placentography

The procedure of rendering the PLACENTA visible by means of X-rays. This can be done either by using what is known as soft-tissue radiography, or by injecting a radio-opaque substance into the bloodstream or into the amniotic cavity (see AMNION). The procedure has some risk to both mother and fetus, and is carried out under expert supervision. It can help to assess the cause of antepartum haemorrhage. The placenta and fetus can now be visualised by the non-invasive and safe method of ULTRASOUND.... placentography

Plantar

Describing anything related to the sole of the foot.... plantar

Plasma Cells

These are cells that produce ANTIBODIES and occur in bone-forming tissue as well as the lining of the gastrointestinal tract and the lungs. The cells develop in LYMPH NODES, SPLEEN and BONE MARROW when T-lymphocytes (see IMMUNITY) are stimulated by antigens (see ANTIGEN) to produce the precursor cells from which plasma cells originate.... plasma cells

Pityriasis

A skin disorder typi?ed by a bran-like desquamation (?aking). There are several varieties including P. alba, rosea, versicolor (fungal caused) and rubra (exfoliative dermatitis).

Pityriasis alba is a mild form of chronic eczema (see DERMATITIS) occurring mainly in children on the face and in young adults on the upper arms. It is characterised by round or oval ?aky patches which are paler than the surrounding skin due to partial loss of MELANIN pigment. The appearance is more dramatic in dark-skinned or suntanned subjects. Moisturising cream often su?ces, but 1 per cent HYDROCORTISONE cream is more e?ective.

Pityriasis rosea is a common self-limiting eruption seen mainly in young adults. It usually begins as a solitary red ?aky patch (often misdiagnosed as ringworm). Within a week this ‘herald patch’ is followed by a profuse symmetrical eruption of smaller rose-pink, ?aky, oval lesions on the trunk and neck but largely sparing the limbs and face. Itching is variable. The eruption usually peaks within 3 weeks and fades away leaving collarettes of scale, disappearing within 6–7 weeks. It rarely recurs and a viral cause is suspected but not proved. It is not contagious and there is no speci?c treatment, but crotamiton cream (Eurax) may relieve discomfort.... pityriasis

Plasmin

Also called ?brinolysin, this is an ENZYME that digests the protein FIBRIN. It dissolves blood clots (see COAGULATION) and so is present in the blood in the form of PLASMINOGEN, an inactive precursor.... plasmin

Plasminogen

A precursor of PLASMIN, an ENZYME that digests the protein FIBRIN – the main constituent of blood clots (see COAGULATION). When tissue is damaged, activators are released which provoke the conversion of plasminogen into plasmin.... plasminogen

Plasmodium

The general term applied to minute protoplasmic cells, and particularly to those which cause MALARIA and allied diseases.... plasmodium

Plerocercoid

The third stage larva of pseudophyllidean tapeworms, which has a solid body.... plerocercoid

Pleural Cavity

The normally restricted space between the parietal and the visceral PLEURA, which slide over one another as the individual breathes in and out. If gas or ?uid are introduced as a result of injury or infection, the pleural surfaces are separated and the pleural space increases in volume. This usually causes breathing diffculties.... pleural cavity

Plum

(American) Resembling the fruit ... plum

Plumbism

Another name for LEAD POISONING.... plumbism

Plummer-vinson Syndrome

Hypochromic ANAEMIA and di?culty in swallowing due to an oesophageal web.... plummer-vinson syndrome

Pneumocystis Pneumonia

PNEUMONIA caused by a species of the genus of PROTOZOA, a parasitic micro-organism. Pneumocystis carinii causes an opportunistic infection in the lung which is dangerous to people whose immune system is impaired (see IMMUNITY), thus reducing their resistance to infections. People with AIDS/HIV or LEUKAEMIA have impaired immune systems and P. carinii is a major cause of death in the former. Fever, dry cough and breathlessness are among the symptoms; treatment is with high doses of antibiotic drugs such as CO-TRIMOXAZOLE or PENTAMIDINE.... pneumocystis pneumonia

Pneumoperitoneum

A collection of air in the peritoneal cavity (see PERITONEUM). Air introduced into the peritoneal cavity collects under the diaphragm which is thus raised and collapses the lungs. This procedure was sometimes carried out in the treatment of pulmonary tuberculosis in the pre-antibiotic days as an alternative to arti?cial PNEUMOTHORAX.... pneumoperitoneum

Podagra

Another name for GOUT affecting the foot.... podagra

Podophyllin

A resin derived from podophyllum plants, its active agent, podophyllotoxin, in alcoholic solution is used to treat genital WARTS. Paints, creams and impregnated plasters are used for calluses and warts elsewhere.... podophyllin

Poikilocytosis

This is a term used to describe the variation seen in the shape of red blood cells in some disorders of the BONE MARROW.... poikilocytosis

Pollex

A Latin term for thumb.... pollex

Polychromasia

Also polychromatophilia; terms applied to an abnormal reaction of the red blood cells in severe ANAEMIA. They have a bluish tinge instead of the normal red colour in a blood ?lm stained by the usual method. It is a sign that the cell is not fully developed.... polychromasia

Polydactyly

The presence of extra, or supernumerary, ?ngers or toes.... polydactyly

Polygene

One of several GENES that between them control a single characteristic in an individual. With each polygene exerting a slight e?ect, the genetic outcome is the consequence of ‘group action’. The hereditary characteristics produced in this way are usually those of a quantitative type – for instance, an individual’s height.... polygene

Polycystic Ovary Syndrome

Characterised by scanty (or absent) MENSTRUATION, INFERTILITY, hirsutism (excessive hairiness) and OBESITY and the sufferers often have multiple cysts in their OVARIES.

The condition is caused by an imbalance between LUTEINISING HORMONE (LH) and FOLLICLE-STIMULATING HORMONE (FSH); this imbalance stops OVULATION and varies the TESTOSTERONE output of the ovaries. The treatment may be with CLOMIPHENE; with a PROGESTOGEN drug; with LUTEINISING HORMONE-RELEASING HORMONE (LHRH); or with oral contraceptives (see under CONTRACEPTION – Non-barrier methods). The treatment chosen depends on the severity of the disease and whether the woman wants to conceive. Rarely a section of ovarian tissue is surgically removed.... polycystic ovary syndrome

Polymorph

(Diminutive of polymorphonuclear leucocyte.) A name applied to certain white corpuscles of the blood which have a nucleus of irregular and varied shape. These form between 70 and 75 per cent of all the white corpuscles. (See BLOOD.)... polymorph

Polymorphism

Wide varieties of form of a species.... polymorphism

Polyneuritis

An in?ammatory condition of nerves in various parts of the body. (See NEURITIS.)... polyneuritis

Polyposis

The presence of a crop, or large number, of polypi (see POLYPUS). The most important form of polyposis is that known as familial polyposis coli. This is a hereditary disease characterised by the presence of large numbers of polypoid tumours in the large bowel. Every child born to an affected parent stands a ?fty-?fty chance of developing the disease. Its importance is that sooner or later one or more of these tumours undergoes cancerous change. If the affected gut is removed surgically before this occurs, and preferably before the age of 20, the results are excellent.... polyposis

Polysaccharide

A CARBOHYDRATE comprising several monosaccharides linked in long chains. Polysaccharides store energy – as starch in plants and glycogen in animals – and they also form the structural parts of plants (as cellulose) and animals (as mucopolysaccharides).... polysaccharide

Polypus

or polyp (plural: polypi). A general name applied to tumours which are attached by a stalk to the surface from which they spring. The term refers only to the shape of the growth and has nothing to do with its structure or nature. Most polypi are of a simple nature, although malignant polypi are also found. The usual structure of a polypus is that of a ?ne ?brous core covered with epithelium resembling that of the surrounding surface. The sites in which polypi are most usually found are the interior of the nose, the outer meatus of the ear, and the interior of the womb, bladder, or bowels (see POLYPOSIS).

Their removal is generally easy, as they are simply twisted o?, or cut o?, by some form of snare or ligature. (The tissue removed should be checked for malignant cells.) Those which are situated in the interior of the bladder or bowels, and whose presence is usually recognised because blood appears in the urine or stools, require a more serious operation – usually an endoscopic examination (see ENDOSCOPE).... polypus

Pomegranate

Punica granatum

Punicaceae

San: Dadimah;

Hin: Anar, Dhalim;

Ben: Dalim;

Tam: Madalai, Madalam;

Mal: Urumampazham, Matalam, Talimatala m, Matalanarakam; Kan :Dalimbe;

Tel: Dadima; Mar: Dalimba;

Guj: Dadam; Ass: Dalin

Importance: Pomegranate has long been esteemed as food and medicine and as a diet in convalescence after diarrhoea. The rind of the fruit is highly effective in chronic diarrhoea and dysentery, dyspepsia, colitis, piles and uterine disorders. The powdered drug boiled with buttermilk is an efficacious reme dy for infantile diarrohoea. The root and stem bark are good for tapeworm and for strengthening the gums. The flowers are useful in vomiting, vitiated conditions of pitta, ophthalmodynia, ulcers, pharyngodynia and hydrocele. An extract of the flowers is very specific for epistaxis. The fruits are useful in anaemia, hyperdipsia, pharyngodynia, ophthalmodynia, pectoral diseases, splenopathy, bronchitis and otalgia. The fruit rind is good for dysentery, diarrhoea and gastralgia. Seeds are good for scabies, hepatopathy and splenopathy. The important preparations using the drug are Dadimadighrtam, Dadimastaka churnam, Hinguvacadi churnam, Hingvadi gulika, etc (Sivarajan et al, 1994, Warrier et al, 1995).

Distribution: Pomegranate is a native of Iran, Afghanistan and Baluchistan. It is found growing wild in the warm valleys and outer hills of the Himalaya between 900m and 1800m altitude. It is cultivated throughout India, the largest area being in Maharastra.

Botany: Punica granatum Linn. belongs to the family Punicaceace. It is a large deciduous shrub up to 10m in height with smooth dark grey bark and often spinescent branchlets. Leaves are opposite, glabrous, minutely pellucid-punctuate, shining above and bright green beneath. Flowers are scarlet red or sometime yellow, mostly solitary, sometimes 2-4 held together. Stamens are numerous and inserted on the calyx below the petals at various levels. Fruits are globose, crowned by the persistent calyx. Rind is coriaceous and woody, interior septate with membraneous walls containing numerous seeds. Seeds are angular with red, pink or whitish, fleshy testa (Warrier et al, 1995).

Agrotechnology: Pomegranate is of deciduous nature in areas where winters are cold, but on the plains it is evergreen. A hot dry summer aids in the production of best fruits. Plants are grown from seeds as well as cuttings. Mature wood pieces cut into lengths of about 30cm are planted for rooting. The rooted plants are planted 4.5-6m apart. When planted close, they form a hedge which also yields fruits. Normal cultivation and irrigation practices are satisfactory for the pomegranate. An application of 30-45kg of FYM annually to each tree helps to produce superior quality fruits. The pomegranate may be trained as a tree with a single stem for 30-45cm or as a bush with 3 or 4 main stems. In either case suckers arising from the roots and similar growths from the trunk and main branches are removed once a year. Shortening of long slender branches and occasional thinning of branches should be done. The fruit has a tough rind and hence transportation loss is minimum (ICAR, 1966).

Properties and activity: Pomegranate fruit rind gives an ellagitannin named granatin B, punicalagin, punicalin and ellagic acid. Bark contains the alkaloids such as iso-pelletierine, pseudopelletierine, methyl isopelletierine, methyl pelletierine, pelletierine as well as iso-quercetin, friedelin, D- mannitol and estrone. Flowers give pelargonidin-3, 5-diglucoside apart from sitosterol, ursolic acid, maslinic acid, asiatic acid, sitosterol- -D-glucoside and gallic acid. Seeds give malvidin pentose glycoside. Rind gives pentose glycosides of malvidin and pentunidin. Fluoride, calcium, magnesium, vitamin C and phosphate are also reported from fruits. Leaves give elligatannins-granatins A and B and punicafolin.

Rind of fruit is astringent, fruit is laxative. Bark of stem and root is anthelmintic, and febrifuge. Rind of fruit and bark of stem and root is antidiarrhoeal. Pericarp possesses antifertility effect. Fixed oil from seeds are antibacterial. Bark, fruit pulp, flower and leaf are antifungal. Aerial part is CNS depressant, diuretic and hypothermic. The flower buds of pomegranate in combination with other plants showed excellent response to the patients of Giardiasis (Mayer et al, 1977; Singhal et al, 1983).... pomegranate

Portal System

A vein or collection of veins which ?nish at both ends in a bed of capillary blood vessels. An important example is the hepatic portal system, comprising the portal vein and its tributaries. Blood from the stomach, pancreas, spleen and intestines drains into the veins that join up to comprise the portal vein into the liver, where it branches into sinusoids.... portal system

Portal Vein

The vein which carries to the LIVER, blood that has been circulating in many of the abdominal organs. It is peculiar among the veins of the body in that it ends by breaking up into a capillary network instead of carrying the blood directly to the heart – a peculiarity which it shares only with certain small vessels in the kidneys. The PORTAL SYSTEM begins below in the haemorrhoidal plexus of veins around the lower end of the rectum; from this point, along the whole length of the intestines, the blood is collected into an inferior mesenteric vein upon the left, and a superior mesenteric vein upon the right side. The inferior mesenteric vein empties into the splenic vein, and the latter, uniting with the superior mesenteric vein immediately above the pancreas, forms the portal vein. The portal vein is joined by veins from the stomach and gallbladder, and ?nally divides into two branches which sink into the right and left lobes of the liver. (For their further course, see LIVER).

The organs from which the portal vein collects the blood are the large and small intestines, the stomach, spleen, pancreas, and gall-bladder.... portal vein

Post

A pre?x signifying after or behind.... post

Post-viral Fatigue Syndrome

See MYALGIC ENCEPHALOMYELITIS (ME).... post-viral fatigue syndrome

Postpartum

After birthing.... postpartum

Postural Drainage

Facilitation of the drainage of secretions from dilated bronchi of the LUNGS. The patient lies on an inclined plane, head downwards, and is encouraged to cough up as much secretion from the lungs as possible. The precise position depends on which part of the lungs is affected. It may need to be carried out for up to three hours daily in divided periods. It is of particular value in BRONCHIECTASIS and lung abscess (see LUNGS, DISEASES OF).... postural drainage

Powder

(American) A lighthearted woman Powdar, Powdir, Powdur, Powdor, Powdi, Powdie, Powdy, Powdey, Powdee, Powdea... powder

Power Of Attorney

See “durable power of attorney”.... power of attorney

Precipitin

An antibody (see ANTIBODIES) that combines with an ANTIGEN and forms the immune complex as a precipitate. The reaction is used in some diagnostic serological tests to identify antigens in the serum.... precipitin

Prednisone

This corticosteroid drug has a similar level of glucocorticoid activity as PREDNISOLONE and is converted to prednisolone in the liver. Though prednisone is still in use, prednisolone is the most commonly used oral corticosteroid for long-term anti-in?ammatory treatment. (See CORTICOSTEROIDS; GLUCOCORTICOIDS.)... prednisone

Premature Beat

See ECTOPIC BEAT.... premature beat

Premature Birth

See ABORTION; FETUS; PREGNANCY AND LABOUR.... premature birth

Pregnancy Tests

There are several tests for pregnancy (see PREGNANCY AND LABOUR) in its early stages, and these can be done on blood or urine; some of the urine tests may be carried out at home. Most tests are based on the detection of HUMAN CHORIONIC GONADOTROPHIN (HCG) in the woman’s urine. They are nearly 100 per cent accurate and may show positive as early as 30 days after the ?rst day of the last normal period.

The haemagglutination inhibition test This, and the subsequent tests to be mentioned, are known as immunological tests. They are based upon the e?ect of the urine from a pregnant woman upon the interaction of red blood cells, which have been sensitised to human gonadotrophin, and anti-gonadotrophin serum. They have the great practical advantage of being performed in a test-tube or even on a slide. Because of their ease and speed of performance, a result can be obtained in two hours.

Enzyme-linked immunosorbent assay (ELISA) This is the basis of many of the pregnancy-testing kits obtainable from pharmacies. It is a highly sensitive antibody test and can detect very low concentrations of human chorionic gonadotrophin. Positive results show up as early as ten days after fertilisation – namely, four days before the ?rst missed period.

Ultrasound The fetal sac can be detected by ULTRASOUND from ?ve weeks, and a fetal echo at around six or seven weeks (see also PRENATAL SCREENING OR DIAGNOSIS).... pregnancy tests

Prescribed Diseases

A collection of industrial diseases which provide those with a disease legal entitlement to welfare bene?ts. Examples are DEAFNESS from excessive noise in the workplace; ANTHRAX from farming; PNEUMOCONIOSIS from industrially generated dust (coal mining); and LEAD POISONING from the handling of chemicals. (See also OCCUPATIONAL HEALTH, MEDICINE AND DISEASES.)... prescribed diseases

Presentation

The appearance in labour of some particular part of the child’s body at the mouth of the uterus (see PREGNANCY AND LABOUR). This is a head presentation in 96 per cent of cases, but in a certain number the breech (or buttocks) may present, or the face, or foot, or even a part of the trunk in cases of cross-birth.

The term is also used for the symptoms or signs with which a patient ?rst brings to a doctor.... presentation

Pressure Sores

See ULCER – Decubitus ulcer.... pressure sores

Prickly Ash

Xanthoxylum americanum. N.O. Rutaceae.

Synonym: Toothache Bush or Suterberry.

Habitat: Flourishes in moist places throughout the United States, from which country the medicinal berries and bark are imported.

Features ? A shrub varying between ten and fifteen feet in height with alternate branches covered with strong, sharp prickles, the leaves are pinnate, with lanceolate leaflets, the flowers green and white. Small, blue-black berries enclosed in a grey shell grow in clusters on the top of the branches. The bark is about one- twelfth of an inch thick, and has corky, conical spines nearly one inch in height. Fractures show green in the outer part and yellow in the inner. The taste is very pungent, causing salivation, and there is little odour.

Part used ? Berries and bark, the berries being considered the more effective.

Action: Stimulant, alterative, nervine and diaphoretic.

An infusion of the berries, or the crushed or powdered bark, is made in the proportion of 1/2 ounce to 1 pint of boiling water, the dose being one tablespoonful four times daily. The infusion should be allowed to stand in a covered vessel for two hours before use.

In the treatment of chronic rheumatic trouble this medicine is given a prominent place, and it is also widely used wherever a general stimulant is needed. The powdered bark is applied directly to indolent ulcers. As an external application for rheumatism. Coffin recommends 1 ounce of the pulverised bark to 4 ounces of Olive oil, heated, the part to be well rubbed with this liniment night and morning.... prickly ash

Primary Care Trust

See GENERAL PRACTITIONER (GP)... primary care trust

Prickly Pear Cactus

Opuntia species

Description: This cactus has flat, padlike stems that are green. Many round, furry dots that contain sharp-pointed hairs cover these stems.

Habitat and Distribution: This cactus is found in arid and semiarid regions and in dry, sandy areas of wetter regions throughout most of the United States and Central and South America. Some species are planted in arid and semiarid regions of other parts of the world.

Edible Parts: All parts of the plant are edible. Peel the fruits and eat them fresh or crush them to prepare a refreshing drink. Avoid the tiny, pointed hairs. Roast the seeds and grind them to a flour.

CAUTION

Avoid any prickly pear cactus like plant with milky sap.

Other Uses: The pad is a good source of water. Peel it carefully to remove all sharp hairs before putting it in your mouth. You can also use the pads to promote healing. Split them and apply the pulp to wounds.... prickly pear cactus

Primigravida

A woman who is undergoing her ?rst pregnancy (see PREGNANCY AND LABOUR).... primigravida

Primipara

The term applied to a woman who has given birth, or is giving birth, to her ?rst child (see PREGNANCY AND LABOUR).... primipara

Primrose

(Latin) The first rose; resembling the flower

Prymrose, Primula, Primulia, Primrosa, Prymrosa... primrose

Privacy

The state of being free from unsanctioned intrusion. For example, personal privacy in daily living activities (e.g. for clients in residential facilities) or confidential health records.... privacy

Probe

A slender, ?exible instrument, usually made of metal, designed for introduction into a wound or cavity – to explore its depth and direction, to discover the presence of foreign bodies, or to introduce medicinal substances.... probe

Probiotics

Viable BACTERIA that colonise the intestine and alter the micro?ora and their metabolic activities, with a presumed bene?cial e?ect for the host. Many probiotics are LACTIC ACID bacteria

– for example, LACTOBACILLUS or bi?dobacterium. Not all probiotics have the same properties or e?ectiveness. To be e?ective, a probiotic must survive passage through the stomach – an acid environment – and successfully colonise in the intestines, even when antibiotics are present. Research suggests that probiotics ameliorate the symptoms of childhood and travellers’ DIARRHOEA, reducing the period of acute symptoms – particularly if the infection is caused by one of the ROTAVIRUSES.... probiotics

Procaine

Once used widely as a local anaesthetic, but rarely so now.... procaine

Process

A continuous and regular action or succession of actions taking place or being carried out in a definite manner and leading to the accomplishment of some results.... process

Progestogen

One of a naturally occurring or synthetically produced group of steroid HORMONES, including PROGESTERONE, that help to maintain normal pregnancy. Progestogens are used in contraceptives (see CONTRACEPTION) and are useful in treating AMENORRHOEA, premenstrual tension, and abnormal uterine bleeding.... progestogen

Prolapsed Intervertebral Disc

The SPINAL COLUMN is built up of a series of bones, known as vertebrae, placed one upon the other. Between these vertebrae lies a series of thick discs of ?bro-cartilage known as intervertebral discs. Each disc consists of an outer portion known as the anulus ?brosus, and an inner core known as the nucleus pulposus. The function of these discs is to give ?exibility and resiliency to the spinal column and to act as bu?ers against undue jarring. In other words, they are most e?cient shock-absorbers. They may, however, PROLAPSE, or protrude, between the two adjacent vertebrae. If this should happen they press on the neighbouring spinal nerve and cause pain. As the most common sites of protrusion are between the last two lumbar vertebrae and between the last lumbar vertebra and the sacrum, this means that the pain occurs in the back, causing LUMBAGO, or down the course of the sciatic nerve causing SCIATICA. The prolapse is most likely to occur in middle age, which suggests that it may be associated with degeneration of the disc involved, but it can occur in early adult life as well. It usually occurs when the individual is performing some form of exercise which involves bending or twisting, as in gardening. The onset of pain may be acute and sudden, or gradual and more chronic in intensity. (See also INTERVERTEBRAL DISC.)

Treatment varies, depending (amongst other things) on the severity of the condition. In the acute phase, rest in bed is advisable, along with ANALGESICS. Later, exercise and physiotherapy are helpful, and in some cases manipulation of the spine brings relief by allowing the herniated, or prolapsed, disc to slip back into position. The injection of a local anaesthetic into the spine (epidural ANAESTHESIA) is yet another measure that often helps the more chronic cases. If those measures fail, surgery to remove the prolapsed disc may be necessary, but the patient’s condition should be carefully reviewed before surgery is considered since success is not certain. An alternative form of treatment is the injection into the disc of chymopapain, an ENZYME obtained from the paw-paw, which dissolves the disc.... prolapsed intervertebral disc

Prone

Lying with the face down, or positioning the arm and hand so that the palm faces downwards.... prone

Prophylaxis

Treatment or action adopted with the view of warding o? disease.... prophylaxis

Propofol

A drug used intravenously to induce general ANAESTHESIA. Propofol may be used by intravenous infusion to maintain anaesthesia; it is also useful for sedating patients in intensive care.... propofol

Proprietary Name

The trade name of a drug registered by the pharmaceutical company which has developed and patented it. This protects the name, ingredients and manufacturing technique for a set period of time, and helps the company to recoup the often costly research and development needed to produce and test the drug. Doctors may prescribe a drug by its trade name or by its o?cial, approved name, although the NHS encourages the latter. (See GENERIC DRUG; PATENT.)... proprietary name

Proptometer

See EXOPHTHALMOMETER.... proptometer

Prostacyclin

A prostaglandin (see PROSTAGLANDINS) produced by the endothelial lining of the blood vessels. It inhibits the aggregation of PLATELETS, and thereby reduces the likelihood of the blood clotting. It is also a strong vasodilator (see VASODILATORS).... prostacyclin

Prostatism

The condition induced by benign enlargement of the PROSTATE GLAND.... prostatism

Protease

A digestive ENZYME – also known as a proteolytic enzyme – that breaks down PROTEIN in food as part of the digestive process. The complex protein molecules are reduced to their constituent AMINO ACIDS.... protease

Proton Pump

A key enzyme system in the parietal cells of the mucosal lining of the stomach: hydrogen ions are produced which acidify the stomach’s secretions and convert pepsinogen to PEPSIN, an active participant in the digestion of food.... proton pump

Proton-pump Inhibitors

These are drugs that inhibit the production of acid in the stomach by blocking a key enzyme system, known as the PROTON PUMP, of the parietal cells of the stomach. The drugs include omeprazole, lansoprazole and pantoprazole, and they are the treatment of choice for oesophagitis (erosion and stricture – see under OESOPHAGUS, DISEASES OF); for the short-term treatment for gastric ulcer (see under STOMACH, DISEASES OF) and DUODENAL ULCER; and, in combination with ANTIBIOTICS, for the eradication of Helicobacter pylori.... proton-pump inhibitors

Protriptyline

One of the tricyclic ANTIDEPRESSANT DRUGS. (See MENTAL ILLNESS.)... protriptyline

Prozac

See FLUOXETINE.... prozac

Proteolysis

The mechanism by which complex PROTEIN molecules are broken down by digestive enzymes (see PROTEASE) in the stomach and small intestine. The constituent AMINO ACIDS are then absorbed into the bloodstream.... proteolysis

Prothrombin

An inactive substance in the blood PLASMA that is the precursor of the ENZYME, thrombin, which clots the blood. The conversion occurs when a blood vessel is damaged and the process of blood COAGULATION occurs.... prothrombin

Proto-oncogene

A gene in a cell that regulates cell growth and development in an orderly fashion. If a protooncogene mutates, it can give rise to cancer by causing growth without the normal controls. The proto-oncogene is then called an oncogene.... proto-oncogene

Pseudocyst

A space within an organ without a de?ned lining and which contains ?uid. Patients with chronic pancreatitis (see PANCREAS, DISORDERS OF) sometimes develop these pseudocysts which ?ll with pancreatic juice containing enzymes produced by the gland. Abdominal pain usually results; treatment is by surgical draining.... pseudocyst

Pseudoxanthoma Elasticum

This is a hereditary disorder of elastic tissue. Degenerating elastic tissue in the skin produces lesions which look like soft yellow papules. Elastic tissue in the eye and blood vessels is also involved, giving rise to visual impairment, raised blood pressure and haemorrhages.... pseudoxanthoma elasticum

Psoas

A powerful muscle which arises from the front of the vertebral column in the lumbar region, and passes down, round the pelvis and through the groin, to be attached to the inner side of the thigh-bone not far from its upper end. The act of sitting up from a recumbent posture, or that of bending the thigh on the abdomen, is mainly accomplished by the contraction of this muscle. Disease of the spine in the lumbar region may produce an ABSCESS which lies within the sheath of this muscle and makes its way down to the front of the thigh. Such an abscess is known as a psoas abscess.... psoas

Psychogeriatrics

The branch of PSYCHIATRY that investigates, diagnoses and treats the mental-health problems of old people. Psychogeriatricians work in close co-operation with physicians for the care of the elderly, and with other health professionals and social workers in this branch of medicine.... psychogeriatrics

Psychologist

Psychologists have a graduate degree in PSYCHOLOGY, followed by an accredited postgraduate training leading to chartered status. There are a number of di?erent branches related to the various applications psychology has to di?erent ?elds of work.... psychologist

Psychometrics

The use of standardised psychological tests to measure di?erences in functions – for example, intelligence and personality – in individuals.... psychometrics

Psychoneurosis

A general term applied to various functional disorders of the nervous system. (See NEUROSIS.)... psychoneurosis

Psychopathy

Any disease of the mind... psychopathy

Psychotropic

A?ecting the mind. Psychotropic drugs include HALLUCINOGENS, HYPNOTICS or sleeping drugs, sedatives, TRANQUILLISERS and NEUROLEPTICS (antipsychotic drugs).... psychotropic

Ptyalin

The name of the ENZYME contained in the SALIVA, by which starchy materials are changed into sugar, and so prepared for absorption. It is identical to the AMYLASE of pancreatic juice. (See DIGESTION; PANCREAS.)... ptyalin

Pubis

Pubis is the bone that forms the front part of the pelvis. The pubic bones of opposite sides meet in the symphysis and protect the bladder from the front.... pubis

Pudendal Nerve

The nerve that operates the lowest muscles of the ?oor of the PELVIS and also the anal SPHINCTER muscle. It may be damaged in childbirth, resulting in INCONTINENCE.... pudendal nerve

Pudendum

The external genital organs. The term is usually used to describe those of the female (see VULVA).... pudendum

Pulmonary Fibrosis

A condition which may develop in both LUNGS (interstitial pulmonary ?brosis) or part of one lung. Scarring and thickening of lung tissues occur as a consequence of previous lung in?ammation, which may have been caused by PNEUMONIA or TUBERCULOSIS. Symptoms include cough and breathlessness and diagnosis is con?rmed with a chest X-ray. The patient’s underlying condition should be treated, but the damage already done to lung tissue is usually irreversible. (See also ALVEOLITIS.)... pulmonary fibrosis

Puerperal Sepsis

An infection, once called puerperal fever, that starts in the genital tract within ten days after childbirth, miscarriage or abortion (see PREGNANCY AND LABOUR). Once a scourge of childbirth, with many women dying from the infection, the past 50 years have seen a dramatic decline in its incidence in developed countries, with only 1–3 per cent of women having babies now being affected. This decline is due to much better maternity care and the advent of ANTIBIOTICS. Infection usually starts in the VAGINA and is caused by the bacteria that normally live in it: they can cause harm because of the mother’s lowered resistance, or when part of the PLACENTA has been retained in the genital tract. The infection usually spreads to the UTERUS and sometimes to the FALLOPIAN TUBES. Sometimes bacteria may enter the vagina from other parts of the body.

Fever, an o?ensive-smelling post-partum vaginal discharge (lochia) and pain in the lower abdomen are the main features. Untreated, the women may develop SALPINGITIS, PERITONITIS and septicaemia. Antibiotics are used to treat the infection and any retained placental tissue must be removed.... puerperal sepsis

Pulmonary Function Tests

Tests to assess how the LUNGS are functioning. They range from simple spirometry (measuring breathing capacity) to sophisticated physiological assessments.

Static lung volumes and capacities can be measured: these include vital capacity – the maximum volume of air that can be exhaled slowly and completely after a maximum deep breath; forced vital capacity is a similar manoeuvre using maximal forceful exhalation and can be measured along with expiratory ?ow rates using simple spirometry; total lung capacity is the total volume of air in the chest after a deep breath in; functional residual capacity is the volume of air in the lungs at the end of a normal expiration, with all respiratory muscles relaxed.

Dynamic lung volumes and ?ow rates re?ect the state of the airways. The forced expiratory volume (FEV) is the amount of air forcefully exhaled during the ?rst second after a full breath – it normally accounts for over 75 per cent of the vital capacity. Maximal voluntary ventilation is calculated by asking the patient to breathe as deeply and quickly as possible for 12 seconds; this test can be used to check the internal consistency of other tests and the extent of co-operation by the patient, important when assessing possible neuromuscular weakness affecting respiration. There are several other more sophisticated tests which may not be necessary when assessing most patients. Measurement of arterial blood gases is also an important part of any assessment of lung function.... pulmonary function tests

Pulp

See under TEETH.... pulp

Pulpitis

Inflammation, usually infectious, of the pulp of a tooth.... pulpitis

Pulsus Paradoxus

A big fall in a person’s systolic BLOOD PRESSURE when he or she breathes in. It may occur in conditions such as constrictive PERICARDITIS and pericardial e?usion, when the normal pumping action of the heart is hindered. ASTHMA may also cause pulsus paradoxus, as can CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD).... pulsus paradoxus

Punctum

See EYE – Eyelids.... punctum

Puncture

Description of a wound made by a sharp object, such as a knife, or by a surgical instrument. Puncture wounds, whether accidental (e.g. from a car accident) or deliberate (e.g. from a ?ght), are potentially dangerous. Despite an often small entry hole, serious damage may have been done to underlying tissues – for example, HEART, LUNGS, LIVER, or large blood vessel – and surgical exploration may be required to assess the extent of the injury. Punctures through the skin are also done deliberately in medicine to extract ?uid or tissue through a hollow needle so that it can be examined in the laboratory. LUMBAR PUNCTURE, where cerebrospinal ?uid is withdrawn, is one example.... puncture

Purkinje Cells

Large specialised nerve cells occurring in great numbers in the cortex (super?cial layer of grey matter) of the cerebellum of the BRAIN. They have a ?ask-shaped body, an AXON and branching tree-like extensions called dendrites, which extend towards the surface of the brain (see NEURON(E)).... purkinje cells

Purslane

Portulaca oleracea

Description: This plant grows close to the ground. It is seldom more than a few centimeters tall. Its stems and leaves are fleshy and often tinged with red. It has paddleshaped leaves, 2.5 centimeter or less long, clustered at the tips of the stems. Its flowers are yellow or pink. Its seeds are tiny and black.

Habitat and Distribution: It grows in full sun in cultivated fields, field margins, and other weedy areas throughout the world.

Edible Parts: All parts are edible. Wash and boil the plants for a tasty vegetable or eat them raw. Use the seeds as a flour substitute or eat them raw.... purslane

Putrefaction

The change that takes place in the bodies of plants and animals after death, whereby they are ultimately reduced to carbonic acid gas, ammonia, and other simple substances. The change is almost entirely due to the action of bacteria, and, in the course of the process, various o?ensive and poisonous intermediate substances are formed. In the case of the human body, putrescine, cadaverine, and other alkaloids are among these intermediate products.... putrefaction

Purging Croton

Croton tiglium

Euphorbiaceae

San: Jepalah, Dantibijah

Hin: Jamalgota

Ben: Jaypal Mal: Nirvalam

Tam: Nervalam, Sevalamkottai

Tel: Nepala

Importance: Purging croton or croton oil plant, a small evergreen tree with separate male and female flowers, is one among the seven poisons described in Ayurveda. The drug is well known for its drastic purgative property. The drug is found to be useful in ascites, anasarca, cold, cough, asthma, constipation, calculus, dropsy, fever and enlargement of the abdominal viscera. The seed paste is a good application for skin diseases, painful swellings and alopacia. The seed-oil is useful in chronic bronchitis, laryngeal affections, arthritis and lock jaw. Misraka-sneham is an important preparation using the drug (Nadkarni, 1954; Dey, 1980; Sharma, 1983).

Distribution: It is distributed throughout North India. It is cultivated in Assam, West Bengal and South India.

Botany: Croton tiglium Linn. belongs to the family Euphorbiaceae. It is a small evergreen tree, 4.5-6.0m in height with ash coloured smooth bark and young shoots sprinkled with stellate hairs. Leaves are oblong to ovate-lanceolate, obtuse or rounded at the 2-glanded box, acuminate, membraneous, yellowish green and minutely toothed. Flowers are small, unisexual, males on slender pedicels, females larger and on short thick pedicels. Fruits are ovoid or oblong trigonous capsules. Seeds are smooth, testa black and enclosing reddish brown oily endosperm (Warrier et al,1994). Other species belonging to the genus Croton are as follows:

C. aromaticus Linn. C. caudatus Geisel C. jouera Roxb.

C. malabaricus Bedd.

C. oblongifolius Roxb.

C. polyandrus Roxb. syn. Baliospermum montanum Muell-Arg.

C. reticulatus(Chopra et al, 1980)

Agrotechnology: The plant is propagated by seeds. Seeds are to be sown on seedbeds and about 2 months old seedlings are used for transplanting. Pits of size 50cm cube are to be taken at 3m spacing and filled with dried cowdung, sand and topsoil and formed into a mound. The seedlings are to be planted on these mounds. Irrigation during summer months is beneficial. Application of organic manure after every 6 months is desirable. Weeding is to be carried out one month after transplanting. The plant is not attacked by any serious pests or diseases. Fruits are formed at the end of first year. Fruits when ripen and start to crack are to be collected, dried in sun, then the outer shell is removed and again dried for one day before marketing (Prasad et al,1997).

Properties and activity: Oil contains phorbol myristate acetate (Husain et al, 1992). Seeds contain upto 20% protein and 30-50% lipids. Iso-guanine-D-ribose (crotoniside) and saccharose were isolated from the seeds. In fractionation of croton oil, liquid-liquid distribution procedures proved to be the separation tools of choice. The per hydrogenated parent hydrocarbon of phorbol is a perhydrocyclopropabenzulene called tigliane and phorbol is 1, 1a , 1b , 4, 4a, 7a , 7b, 8, 9, 9a-decahydro-4a , 7 , 9 , 9a - tetrahydroxy-3-(hydroxymethyl)-1, 1, 6, 8 tetramethyl-5-H-cyclopropa[3,4] benz [1.2-e]azulen-5- one. Phorbol, a tetracylic diterpene with a 5, 7, 6 and 3- membered ring has 6 oxygen functions. Phorbol accounts for 3.4% and 4- deoxy- 4 - phorbol for 0.29% of the weight of croton oil. Twenty- five phorbol-12, 13-diesters have been detected (Hecker et al, 1974). A toxin croton 1, mol. wt 72,000 has been isolated from the seeds (Lin et al, 1978).

Phorbol myristate acetate activates nitroblue tetrazolium reduction in human polymorphs. Seed and oil is purgative, rubefacient and anti-dote for snakebite. The seeds and oil are acrid, bitter, thermogenic, emollient, drastic purgative, digestive, carminative, anthelmintic, antiinflammatory, vermifuge, deterent, diaphoretic, expectorant, vesicant, irritant and rubefacient.... purging croton

Pyaemia

A form of blood-poisoning in which abscesses (see ABSCESS) appear in various parts of the body. (See also SEPTICAEMIA.)... pyaemia

Pyelogram

See INTRAVENOUS PYELOGRAM (UROGRAM).... pyelogram

Pylephlebitis

In?ammation of the PORTAL VEIN. A rare but serious disorder, it usually results from the spread of infection within the abdomen – for example, appendicitis. The patient may develop liver abscesses and ASCITES. Treatment is by ANTIBIOTICS and surgery.... pylephlebitis

Pyloromyotomy

Also called Ramstedt’s operation, this is a surgical procedure to divide the muscle around the outlet of the stomach (PYLORUS). It is done – usually on babies – to relieve the obstruction caused at the outlet by congenital PYLORIC STENOSIS.... pyloromyotomy

Pylorospasm

Spasm of the pyloric portion of the STOMACH. This interferes with the passage of food in a normal, gentle fashion into the intestine, causing the pain that comes on from half an hour to three hours after meals; it is associated with severe disorders of digestion. It is often produced by an ulcer of the stomach or duodenum.... pylorospasm

Pylorus

The lower opening of the STOMACH, through which the softened and partially digested food passes into the small INTESTINE.... pylorus

Pyogenic

Pus forming... pyogenic

Pyromania

A powerful urge in a person to set things on ?re. A?ected individuals, more commonly males, are called pyromaniacs. They usually have a history of fascination with ?re since childhood and obtain pleasure or relief of tension from causing ?res. Treatment is di?cult and pyromaniacs commonly end up in the courts.... pyromania

Pyrosis

See WATERBRASH.... pyrosis

Sanitary Protection

Disposable sanitary towels or tampons (see TAMPON) used to protect clothing from bloodstains during MENSTRUATION. They are available in different absorbencies to meet women’s individual needs.... sanitary protection

Standard Population

A population in which the age and sex composition is known precisely, as a result of a census. A standard population is used as a comparison group in the procedure for standardizing mortality rates.... standard population

Subacute Sclerosing Panencephalitis

A rare complication of MEASLES due to infection of the brain with the measles virus. It develops 2–18 years after the onset of the measles, and is characterised by mental deterioration leading on to CONVULSIONS, COMA and death. The annual incidence in Britain is about one per million of the childhood population. The risk of its developing is 5–25 times greater after measles than after measles vaccination (see MMR VACCINE; IMMUNISATION).... subacute sclerosing panencephalitis

Systolic Pressure

See BLOOD PRESSURE.... systolic pressure

Targeting / Target Population / Target Group

The group of persons for whom an intervention is planned. For example, the targeting of services to particular user groups.... targeting / target population / target group

Viral Pneumonia

Infection of the lung tissue by a VIRUS. Causes of this type of pneumonia include ADENOVIRUSES, COXSACKIE VIRUSES and in?uenza virus. Viral infections do not respond to ANTIBIOTICS and treatment is symptomatic, with antibiotics used only if the patient develops secondary bacterial infection. In a previously healthy individual the viral infection is usually self-limiting, but in vulnerable patients – the elderly or those with pre-existing disease – it can be fatal.... viral pneumonia

Xeroderma Pigmentosum

A rare disease in which DNA repair mechanisms fail, rendering the skin especially vulnerable to damage from ultraviolet light (see ULTRAVIOLET RAYS (UVR)). Extreme photosensitivity begins in infancy; later, marked freckling occurs and premature CARCINOGENESIS in the skin usually leads to early death. There may also be neurological complications.... xeroderma pigmentosum

Xiphoid Process

Also known as the xiphisternum or xiphoid cartilage, this is the small oval-shaped projection forming the lowest of the three parts of the STERNUM or breastbone.... xiphoid process

Tropical Medicinal Plants

Tropical countries are a treasure house of a wide variety of medicinal plants. Some species are found wild, while a number of species have been domesticated by the farmers. Many species have been grown in homesteads and become part of traditional home remedies. A limited number of species are commercially cultivated though a few more have potential for large-scale production. The important tropical and subtropical medicinal plants are discussed here highlighting the importance, medicinal and other uses, distribution, botany, agrotechnology, chemical constituents and activity. For practical convenience of the discussion in this book, they are classified under the following four broad groups.

a) Medicinal herbs

b) Medicinal shrubs

c) Medicinal climbers

d)Medicinal trees... tropical medicinal plants

Facial Pain

Many causes, including neuralgia, frontal sinusitis, eye troubles (pain of glaucoma being referred to the temples), dental problems, shingles, psychogenic, migraine; pain referred from lungs or heart. See appropriate entries for each of these complaints.

Maria Treben’s Facial Pack: of any of the following – Thyme, Mullein, Chamomile or Yarrow. Fill small muslin bag and steep in boiling water. Ring out. Apply as hot as possible.

Internal: Chamomile tea. ... facial pain

Abdominal Pain

(Acute). Sudden unexplained colicky pain with distension in a healthy person justifies immediate attention by a doctor or suitably trained practitioner. Persistent tenderness, loss of appetite, weight and bowel action should be investigated. Laxatives: not taken for undiagnosed pain. Establish accurate diagnosis.

Treatment. See entries for specific disorders. Teas, powders, tinctures, liquid extracts, or essential oils – see entry of appropriate remedy.

The following are brief indications for action in the absence of a qualified practitioner. Flatulence (gas in the intestine or colon), (Peppermint). Upper right pain due to duodenal ulcer, (Goldenseal). Inflamed pancreas (Dandelion). Gall bladder, (Black root). Liver disorders (Fringe Tree bark). Lower left – diverticulitis, colitis, (Fenugreek seeds). Female organs, (Agnus Castus). Kidney disorders, (Buchu). Bladder, (Parsley Piert). Hiatus hernia (Papaya, Goldenseal). Peptic ulcer, (Irish Moss). Bilious attack (Wild Yam). Gastro-enteritis, (Meadowsweet). Constipation (Senna). Acute appendicitis, pain central, before settling in low right abdomen (Lobelia). Vomiting of blood, (American Cranesbill). Enlargement of abdominal glands is often associated with tonsillitis or glandular disease elsewhere which responds well to Poke root. As a blanket treatment for abdominal pains in general, old-time physicians used Turkey Rhubarb (with, or without Cardamom seed) to prevent griping.

Diet: No food until inflammation disperses. Slippery Elm drinks. ... abdominal pain

Antisocial Personality Disorder

Impulsive, destructive behaviour that often disregards the feelings and rights of others.

People who have an antisocial personality lack a sense of guilt and cannot tolerate frustration.

They may have problems with relationships and are frequently in trouble with the law.

Behaviour therapy, and various forms of psychotherapy, may help to improve integration.

In general, the effects of this disorder decrease with age.... antisocial personality disorder

Benign Prostatic Hyperplasia

(BPH) A medical term for enlargement of the prostate gland (see prostate, enlarged).... benign prostatic hyperplasia

Benzoyl Peroxide

An antiseptic agent used in the treatment of acne and fungal skin infections (see fungal infections). In acne, benzoyl peroxide also acts by removing the surface layer of skin, unblocking sebaceous glands.... benzoyl peroxide

Chronic Obstructive Pulmonary Disease

See pulmonary disease, chronic obstructive.... chronic obstructive pulmonary disease

C-reactive Protein

A protein produced in the body in response to inflammation.... c-reactive protein

Evening Primrose Oil

An oil that is extracted from the seeds of the plant

OENOTHERA BIENNIS, commonly known as the evening primrose. The oil contains an anti-inflammatory substance called gamolenic acid, and is believed by some to be of benefit in treating eczema and premenstrual syndrome.... evening primrose oil

Family Planning

The deliberate limitation or spacing of births. Strategies for family planning include the different methods of contraception. (See also birth control.)... family planning

Mercury Poisoning

The toxic effect of mercury has been known since days of the medieval alchemists. Charles II presented all the symptoms we now recognise as mercurial poisoning, presumably the result of medication received over many years. Its symptoms simulate multiple sclerosis, when chronic. They are: constant fatigue, pins and needles in the limbs, resting tremor, nausea, dizziness, ataxia, pains in the bones and joints, drooling (excessive salivation), blue line along the gums. In children they may include all kinds of vague aches and pains, chorea, hyperthyroidism and facial neuralgia. Weakness, walking difficulties, metallic taste in the mouth, thirst, mental deterioration. It is now known to cause a number of serious nerve dystrophies.

Mercury has an affinity for the central nervous system. Soon it concentrates in the kidney causing tubular damage. A common cause is the mercurial content (50 per cent) in the amalgam fillings in teeth which, under certain conditions, release a vapour. Fortunately, its use in dentistry is being superceded by an alternative composite filling.

A common cause of poisoning was demonstrated in 1972 when 6,000 people became seriously ill (600 died) from eating bread made from grain treated with a fungicide containing methylmercury. For every fungus in grain there is a mercuric compound to destroy it. The seed of all cereal grain is thus treated to protect its power of germination.

Those who are hypersensitive to the metal should as far as possible avoid button cells used in tape recorders, cassette players, watch and camera mechanisms. As the mercury cells corrode, the metal enters the environment and an unknown fraction is converted by micro organisms to alkylmercury compounds which seep into ground waters and eventually are borne to the sea. When cells are incinerated, the mercury volatilises and enters the atmosphere. (Pharmaceutical Journal, July 28/1984)

Mercury poisoning from inhalation of mercury fumes goes directly to the brain and pituitary gland. Autopsies carried out on dentists reveal high concentrations of mercury in the pituitary gland. (The Lancet, 5-27-89,1207 (letter))

Treatment. For years the common antidote was sulphur, and maybe not without reason. When brought into contact sulphur and mercury form an insoluble compound enabling the mercury to be more easily eliminated from the body. Sulphur can be provided by eggs or Garlic.

Old-time backwoods physicians of the North American Medical School used Asafoetida, Guaiacum and Echinacea. German pharmacists once used Bugleweed and Yellow Dock. Dr J. Clarke, USA physician recommends Sarsaparilla to facilitate breakdown and expulsion from the body.

Reconstructed formula. Echinacea 2; Sarsaparilla 1; Guaiacum quarter; Asafoetida quarter; Liquorice quarter. Dose: Liquid Extracts: 1 teaspoon. Tinctures: 2 teaspoons. Powders: 500mg (two 00 capsules or one-third teaspoon). Thrice daily.

Chelation therapy.

Formula. Tinctures. Skullcap 2-15 drops; Pleurisy root 20-45 drops; Horehound 5-40 drops. Mercurial salivation. Thrice daily. (Indian Herbology of North America, by Alma Hutchens) Dental fillings: replace amalgam with safe alternative – ceramic, etc. Evidence of a link between tooth fillings containing mercury and ME has caused the use of dental amalgam to be banned in Sweden. ... mercury poisoning

Human Papillomavirus

A type of virus that is responsible for warts and genital warts.

There are over 50 strains of human papillomavirus.

Infection with some of these strains is thought to be a causative factor in cervical cancer and anal cancer.... human papillomavirus

Keratosis Pilaris

A common condition in which patches of rough skin appear on the upper arms, thighs, and buttocks. The openings of the hair follicles become enlarged by plugs of keratin, and hair growth may be distorted. The condition occurs most commonly in

adolescents and obese people. It is not serious and usually clears up on its own. In severe cases, applying a mixture of salicylic acid and soft paraffin and scrubbing with a loofah may help.... keratosis pilaris

Klumpke’s Paralysis

Paralysis of the lower arm, with wasting of the small muscles in the hand, and numbness of the fingers (excluding the thumb) and of the inside of the forearm.

Klumpke’s paralysis is caused by injury to the 1st thoracic nerve (one of the spinal nerves) in the brachial plexus, which is usually the result of dislocation of the shoulder.... klumpke’s paralysis

Lithotomy Position

Position in which a patient lies on his or her back with the hips and knees bent and the legs wide apart.

Once used for lithotomy, the position is still used for pelvic examinations and some types of pelvic surgery.... lithotomy position

Brachial Plexus

A collection of large nerve trunks that are formed from nerve roots of the lower part of the cervical spine (in the neck) and the upper part of the thoracic spine (in the chest). These nerve trunks divide into the musculocutaneous, axillary, median, ulnar, and radial nerves, which control muscles in and receive sensation from the arm and hand. Injuries to this plexus can cause loss of movement and sensation in the arm.

In severe injuries, there may be damage to both the upper and the lower nerve roots of the brachial plexus, producing complete paralysis of the arm.

Paralysis may be temporary if the stretching was not severe enough to tear nerve fibres.

Nerve roots that have been torn can be repaired by nerve grafting, a microsurgery procedure.

If a nerve root has become separated from the spinal cord, surgical repair will not be successful.

Apart from injuries, the brachial plexus may be compressed by the presence of a cervical rib (extra rib).... brachial plexus

Pancreatectomy

Removal of all or part of the pancreas.

Pancreatectomy may be performed to treat pancreatitis or localized cancer of the pancreas (see pancreas, cancer of).

Rarely, it is performed to treat insulinomas.

Pancreatectomy may lead to diabetes mellitus and malabsorption.... pancreatectomy

Panic Disorder

A type of anxiety disorder, characterized by recurrent panic attacks of intense anxiety and distressing physical symptoms.... panic disorder

Parasitology

The scientific study of parasites. Although viruses and many types of bacteria and fungi are parasites, their study is conducted under the title of microbiology.... parasitology

Parvovirus

A viral infection that causes a rash and joint inflammation. Many children have no symptoms, but some have a bright red rash on the cheeks, a mild fever, and sometimes mild joint inflammation. Symptoms are more severe in adults; they include a rash on the palms and soles of the feet and severe inflammation in the knee, wrist, and hand joints. A diagnosis is made from the symptoms and a blood test. The infection usually clears up within 2 weeks without treatment.... parvovirus

Pasteurization

The process of heating foods to destroy disease-causing microorganisms, and to reduce the numbers of microorganisms responsible for fermentation and putrefaction.... pasteurization

Pathy

A suffix that denotes a disease or disorder.... pathy

Peppermint Oil

An oil obtained from the peppermint plant MENTHA PIPERITA. It is prescribed to relieve abdominal colic but may cause heartburn. Peppermint oil is also used as a flavouring in some drug preparations.... peppermint oil

Perception

The interpretation of a sensation. Information is received through the 5 senses (taste, smell, hearing, vision, and touch) and organized into a pattern by the brain. Factors such as attitude, mood, and expectations affect the final interpretation. Hallucinations are false perceptions that occur in the absence of sensory stimuli.... perception

Perianal Haematoma

A haematoma under the skin around the anus.... perianal haematoma

Periodic Fever

An inherited condition causing recurrent bouts of fever. (See familial Mediterranean fever.)... periodic fever

Periodontal Disease

Any disorder of the periodontium (the tissues that surround and support the teeth).... periodontal disease

Peritoneal Dialysis

See dialysis.... peritoneal dialysis

Pernio

An alternative term for chilblain.... pernio

Persistent Vegetative State

Long-term unconsciousness caused by damage to areas of the brain that control higher mental functions. The eyes may open and close, and there may be random movements of the limbs, but there is no response to stimuli such as pain. Basic functions such as breathing and heartbeat are not affected. There is no treatment to reverse the situation, but, with good nursing care, survival for months or years is possible.... persistent vegetative state

Personality

The sum of a person’s traits, habits, and experiences.

Temperament, intelligence, emotion, and motivation are important aspects.

The development of personality seems to depend on the interaction of heredity and environment.... personality

Pessary

Any of a variety of devices placed in the vagina. Some types are used to correct the position of the uterus (see uterus, prolapse of); others are used as contraceptive devices. The term pessary is also used to refer to a medicated vaginal suppository.... pessary

Peyronie’s Disease

A disorder of the penis in which part of the sheath of fibrous connective tissue thickens, causing the penis to bend during erection. This commonly makes intercourse difficult and painful. Eventually, some of the penile erectile tissue may also thicken. Men over 40 are most often affected. The cause is unknown. The disease may improve without treatment. Otherwise, local injections of corticosteroid drugs or surgical removal of the thickened area and replacement with normal tissue may be carried out.... peyronie’s disease

Phalanges

The small bones that make up the fingers, thumb, and toes.

The thumb and big toe have 2 phalanges; all the other fingers and toes have 3.... phalanges

Pharmaceutical

Any medicinal drug.

The term is also used in relation to the manufacture and sale of drugs.... pharmaceutical

Pharmacognosy

The study or knowledge of the pharmacologically active ingredients of plants.... pharmacognosy

Pharyngeal Pouch

See oesophageal diverticulum.... pharyngeal pouch

Phenobarbital

A barbiturate drug used mainly as an anticonvulsant. It is often used with phenytoin to treat epilepsy. Possible side effects include drowsiness, clumsiness, dizziness, excitement, and confusion.... phenobarbital

Phenylephrine

A decongestant drug used to treat seasonal allergic rhinitis (hay fever) and the common cold. As eye-drops, it is used to dilate the pupils for eye examinations. High doses or prolonged use of nasal preparations may cause headache and blurred vision; stopping taking the drug suddenly may make nasal congestion worse.... phenylephrine

Phenytoin

An anticonvulsant drug used to treat epilepsy and trigeminal neuralgia.

Side effects include nausea, dizziness, tremor, and overgrown and tender gums.... phenytoin

Photorefractive Keratectomy

A surgical treatment for astigmatism, myopia, and hypermetropia, in which areas of the cornea are shaved away by laser.... photorefractive keratectomy

Phototherapy

Treatment with light, including sunlight, ultraviolet light, blue light, or lasers. Moderate exposure to sunlight is the most basic form, and is often helpful in treating psoriasis.

PUVA combines the use of long-wave ultraviolet light with a psoralen drug, which sensitizes the skin to light. This is used to treat psoriasis and other skin diseases such as vitiligo. Psoriasis may also be treated using short-wave ultraviolet light, sometimes combined with the application of coal tar.

Visible blue light is used to treat neonatal jaundice (see jaundice, neonatal), which is due to high levels of the pigment bilirubin in the blood. In phototherapy, bilirubin is converted into a harmless substance that can be excreted. To maximize exposure, the baby is undressed and placed under the lights in an incubator to keep him warm.phrenic nerve One of the pair of main nerves supplying the diaphragm. Each phrenic nerve carries motor impulses to the diaphragm, and plays a part in controlling breathing. Injury to, or surgical cutting of, 1 of the nerves results in paralysis of 1 half of the diaphragm.... phototherapy

Pigmentation

Coloration of the skin, hair, and iris of the eyes by melanin. The more melanin present, the darker the coloration. Blood pigments can also colour skin (such as in a bruise).

There are many abnormalities of pigmentation.

Patches of pale skin occur in psoriasis, pityriasis alba, pityriasis versicolor, and vitiligo.

Albinism is caused by generalized melanin deficiency.

Phenylketonuria results in a reduced melanin level, making sufferers pale-skinned and fair-haired.

Areas of dark skin may be caused by disorders such as eczema or psoriasis, pityriasis versicolor, chloasma, or by some perfumes and cosmetics containing chemicals that cause photosensitivity.

Permanent areas of deep pigmentation, such as freckles and moles (see naevus), are usually due to an abnormality of melanocytes.

Acanthosis nigricans is characterized by dark patches of velvet-like, thickened skin.

Blood pigments may lead to abnormal colouring.

Excess of the bile pigment bilirubin in jaundice turns the skin yellow, and haemochromatosis turns the skin bronze.... pigmentation

Pinguecula

A small, noncancerous, yellowish spot on the conjunctiva over the white of the eye.

They are common in elderly people, and may be removed for cosmetic reasons.... pinguecula

Pink-eye

See conjunctivitis.... pink-eye

Pioglitazone

An oral hypoglycaemic drug that is used in combination with other oral hypoglycaemics (either metformin or a sulphonylurea) in the treatment of type 2 diabetes mellitus.

Pioglitazone acts by reducing peripheral insulin resistance.

Side effects may include gastrointestinal disturbances, weight gain, and anaemia.... pioglitazone

Plantar Wart

See wart, plantar.... plantar wart

Platelet

The smallest type of blood cell, also called a thrombocyte. Platelets play a major role in blood clotting.... platelet

Platyhelminth

A flat or ribbon-shaped parasitic worm. (See liver fluke, schistosomiasis, tapeworm)... platyhelminth

Placental Abruption

Separation of all or part of the placenta from the wall of the uterus before the baby is delivered. The exact cause is not known, but placental abruption is more common in women with long-term hypertension and in those who have had the condition in a previous pregnancy or who have had several pregnancies. Smoking and high alcohol intake may also contribute to the risk of placental abruption.

Symptoms usually occur suddenly and depend on how much of the placenta has separated from the wall of the uterus. They include slight to heavy vaginal bleeding, which can be severe haemorrhaging in complete separation; cramps in the abdomen or backache; severe, constant abdominal pain; and reduced fetal movements. If the bleeding does not stop, or if it starts again, it may be necessary to induce labour (see

A small placental abruption is usu-tal. In more severe

ergency caesarean section is often necessary to save the the life of the fetus. A blood transfusion required.

placenta praevia Implantation of the placenta in the lower part of the uterus, near or over the cervix. Placenta praevia occurs in about 1 in 200 pregnancies. It varies in severity from marginal placenta praevia, when the placenta reaches the edge of the cervical opening, to complete placental praevia, when the entire opening of the cervix is covered. Mild placenta praevia may have no adverse effect. More severe cases often cause painless vaginal bleeding in late pregnancy. If the bleeding is slight and the pregnancy still has several weeks to run, bed rest in hospital may be all that is necessary. The baby will probably be delivered by caesarean section at the 38th week. If the bleeding is heavy or if the pregnancy is near term, an immediate delivery is carried out. placenta, tumours of See choriocarcinoma; hydatidiform mole.... placental abruption

Plethysmography

A way of estimating the blood flow in vessels by measuring changes in the size of a body part.... plethysmography

Plication

A surgical procedure in which tucks are taken in the walls of a hollow organ and then stitched to decrease the size of the organ.... plication

Pneumaturia

The presence of gas in the urine, usually indicating that a fistula has developed between the bladder and the intestine.... pneumaturia

Poly-

A prefix meaning many or much.... poly-

Polycystic Ovary

See ovary, polycystic.... polycystic ovary

Polymerase Chain Reaction

(PCR) A method of rapidly copying DNA sequences so that they can be analysed.... polymerase chain reaction

Polyhydramnios

Excess amniotic fluid surrounding the fetus during pregnancy. It occurs in about 1 in 250 pregnancies and often has no known cause. The condition sometimes occurs if the fetus has a malformation that makes normal swallowing impossible, or if the pregnant woman has diabetes mellitus. The excess amniotic fluid usually accumulates in the 2nd half of pregnancy, producing symptoms from about week 32. The main symptom is abdominal discomfort. Other possible symptoms are breathlessness and swelling of the legs. The uterus is larger than would usually be expected. Occasionally, fluid accumulates rapidly, causing abdominal pain, breathlessness, nausea, and vomiting, and leg swelling. Premature labour may result.

The condition is usually evident from a physical examination, but ultrasound scanning may be needed.

In mild cases, only rest is needed.

In more severe cases, amniotic fluid may be withdrawn using a needle.

In late pregnancy, induction of labour may be performed.... polyhydramnios

Pons

The middle part of the brainstem.... pons

Porphyria

Any of a group of uncommon and usually inherited disorders caused by the accumulation of substances called porphyrins. Sufferers often have a rash or blistering brought on by sunlight, and certain drugs may cause abdominal pain and nervous system disturbances. Porphyrins are formed in the body during the manufacture of haem (a component of haemoglobin). A block in this manufacture causes a build-up of porphyrins. Such blocks are the result of various enzyme deficiencies, which are genetic disorders. Porphyria may also be due to poisoning.

There are 6 types of porphyria. Acute intermittent porphyria usually appears in early adulthood, causing abdominal pain, and often limb cramps, muscle weakness, and psychiatric disturbances. The patient’s urine turns red when left to stand. Barbiturate drugs, phenytoin, oral contraceptives, and tetracyclines precipitate attacks.

Variegate porphyria has similar effects but also causes blistering of sun-exposedskin. Hereditary coproporphyria also has similar effects and may cause additional skin symptoms.

Protoporphyria usually causes skin symptoms after exposure to sunlight, as does porphyria cutanea tarda. In this type, wounds are slow to heal, and urine is sometimes pink or brown. Many cases are precipitated by liver disease.

The rarest and most serious form, congenital erythropoietic porphyria, causes red discoloration of urine and the teeth, excessive hair growth, severe skin blistering and ulceration, and haemolytic anaemia. Death may occur in childhood. Diagnosis is made from abnormal levels of porphyrins in the urine and faeces. Treatment is difficult. Avoiding sunlight and/or precipitating drugs is the most important measure. Acute intermittent porphyria, variegate porphyria, and hereditary coproporphyria may be helped by administration of glucose or haematin. Cases of porphyria cutanea tarda may be helped by venesection.... porphyria

Positron Emission Tomography

See

PET scanning.... positron emission tomography

Postcoital Contraception

See contraception, emergency.... postcoital contraception

Posterior

Relating to the back of the body, or referring to the rear part.... posterior

Postnatal Depression

Depression in a woman after childbirth. The cause is probably a combination of sudden hormonal changes and psychological and environmental factors. The depression ranges from an extremely common and mild, shortlived episode (“baby blues”) to a rare, severe depressive psychosis.

Most mothers first get the “blues” 4–5 days after childbirth and may feel miserable, irritable, and tearful. The cause is hormonal changes, perhaps coupled with a sense of anticlimax or an overwhelming sense of responsibility for the baby. With reassurance and support, the depression usually passes in 2–3 days. In about 10–15 per cent of women, the depression lasts for weeks and causes a constant feeling of tiredness, difficulty in sleeping, loss of appetite, and restlessness. The condition usually clears up of its own accord or is treated with antidepressant drugs.

Depressive psychosis usually starts 2–3 weeks after childbirth, causing severe mental confusion, feelings of worthlessness, threats of suicide or harm to the baby, and sometimes delusions.

Hospital admission, ideally with the baby, and antidepressant drugs are often needed.... postnatal depression

Postpartum Haemorrhage

Excessive blood loss after childbirth. It is more common after a long labour or after a multiple birth. The haemorrhage is usually due to excessive bleeding from the site where the placenta was attached to the uterus.... postpartum haemorrhage

Post-traumatic Stress Disorder

A form of anxiety that develops after a stressful or frightening event.

Common causes include natural disasters, violence, rape, torture, serious physical injury, and military combat.

Symptoms, which may develop many months after the event, include recurring memories or dreams of the event, a sense of personal isolation, and disturbed sleep and concentration.

There may be a deadening of feelings, or irritability and feelings of guilt, sometimes building up to depression.

Most people recover, in time, with emotional support and counselling.... post-traumatic stress disorder

Postural Hypotension

See hypotension.... postural hypotension

Pravastatin

A lipid-lowering drug.... pravastatin

Prazosin

A vasodilator drug used to treat hypertension, heart failure, and Raynaud’s disease.

Prazosin is also used to treat urinary symptoms resulting from an enlarged prostate gland (see prostate, enlarged).

Side effects include dizziness and fainting, nausea, headache, and dry mouth.... prazosin

Precancerous

A term applied to any condition in which there is a tendency for cancer to develop.

There are 3 types of such conditions.

In the 1st, there are no tumours present but the condition carries an increased risk of cancer.

In the 2nd, there are noncancerous tumours that tend to become cancerous or are associated with the development of cancerous tumours elsewhere.

The 3rd type comprises disorders which have irregular features from the beginning but do not always become fully cancerous.... precancerous

Precocious Puberty

The development of secondary sexual characteristics before age 8 in girls and 9 in boys. It is uncommon and may be caused by various disorders that can result in production of sex hormones at an abnormally early age. Possible underlying causes include a brain tumour or other brain abnormalities; abnormality of the adrenal glands (for example, congenital adrenal hyperplasia); ovarian cysts, and tumours, or a tumour in the testes. In some cases, no underlying cause can be identified.

The hormones may cause a premature growth spurt followed by early fusion of the bones. As a result, affected children may initially be tall but, if untreated, final height is often greatly reduced.

The child’s pattern of pubertal development is assessed by a doctor. Blood tests are performed to measure hormone levels. Ultrasound scanning of the ovaries and testes, and CT scanning of the adrenal glands or brain, may also be carried out, depending on the underlying cause suspected.

Treatment is of the underlying cause, and hormone drugs may be given to delay puberty and increase final height.... precocious puberty

Pregnancy

The period from conception to birth. Pregnancy begins with the fertilization of an ovum (egg) and its implantation. The egg develops into the placenta and the embryo, which grows to form the fetus. Most eggs implant into the uterus. Very occasionally, an egg implants into an abnormal site, such as a fallopian tube, resulting in an ectopic pregnancy.

A normal pregnancy lasts around 40 weeks from the first day of the woman’s last menstrual period. It is divided into 3 stages (trimesters) of 3 months each. For the first 8 weeks of pregnancy, the developing baby is called an embryo; thereafter it is called a fetus.

In the 1st trimester the breasts start to swell and may become tender. Morning sickness is common. The baby’s major organs have developed by the end of this stage. During the 2nd trimester, the mother’s nipples enlarge and darken and weight rises rapidly. The baby is usually felt moving by 22 weeks. During the 3rd trimester, stretch marks and colostrum may appear, and Braxton Hick’s contractions may be felt. The baby’s head engages at about 36 weeks.

Common, minor health problems during pregnancy include constipation, haemorrhoids, heartburn, pica, swollen ankles, and varicose veins. Other common disorders include urinary tract infections, stress incontinence (see incontinence, urinary), and candidiasis.Complications of pregnancy and disorders that affect it include antepartum haemorrhage; diabetic pregnancy; miscarriage; polyhydramnios; pre-eclampsia; prematurity; and Rhesus incompatibility. (See also childbirth; fetal heart monitoring; pregnancy, multiple.)... pregnancy

Preventive Dentistry

An aspect of dentistry concerned with the prevention of tooth decay and gum disease.

It consists of the encouragement of good oral hygiene, fluoride treatment, and scaling.... preventive dentistry

Primary Teeth

The 1st teeth (also known as milk teeth), which usually start to appear at age 6 months and are replaced by the permanent teeth from about age 6 years. There are 20 primary teeth, 10 in each jaw. (See also teeth; eruption of teeth; teething.)... primary teeth

Procyclidine

An anticholinergic drug used to treat Parkinson’s disease and minimize the side effects of some antipsychotic drugs. Possible adverse effects include dry mouth and blurred vision.... procyclidine

Prolactinoma

A noncancerous tumour of the pituitary gland that causes overproduction of prolactin. In women, this may result in galactorrhoea, amenorrhoea, or infertility. In men, it may cause impotence and gynaecomastia. In either sex, it may cause headaches, diabetes insipidus, and, if the tumour presses on the optic nerves, loss of the outer visual field. Diagnosis is made from blood tests and CT scanning or MRI of the brain. Treatment may involve removal of the tumour, radiotherapy, or giving the drug bromocriptine.... prolactinoma

Promethazine

An antihistamine drug used to relieve itching in a variety of skin conditions, such as eczema.

It is also used as an antiemetic drug, and sometimes as a premedication.

Possible adverse effects include dry mouth, blurred vision, and drowsiness.... promethazine

Propantheline

An antispasmodic drug used to treat irritable bowel syndrome and forms of urinary incontinence.

Possible adverse effects include dry mouth, blurred vision, and retention of urine.... propantheline

Propranolol

A beta-blocker drug used to treat hypertension, angina pectoris, and cardiac arrhythmias.

It may also be used to reduce the risk of further heart damage after myocardial infarction.

It relieves symptoms of hyperthyroidism and anxiety, and can prevent migraine attacks.

Possible adverse effects are typical of other beta-blocker drugs.... propranolol

Pseudarthrosis

A term meaning false joint, used to describe an operation in which the ends of the 2 opposing bones in a joint are removed and a piece of tissue is fixed in the gap as a cushion.

The term also describes a rare childhood condition in which congenital abnormality of the lower half of the tibia leads to spontaneous fracture.... pseudarthrosis

Pseudodementia

Severe depression in elderly people that mimics dementia. Symptoms include intellectual impairment and loss of memory.... pseudodementia

Pseudogout

A form of arthritis that results from the deposition of calcium pyrophosphate crystals in a joint.

The underlying cause is unknown; in rare cases, it is a complication of diabetes mellitus, hyperparathyroidism, and haemochromatosis.

Symptoms are similar to gout.

Diagnosis is from a sample of joint fluid.

Treatment is with nonsteroidal anti-inflammatory drugs (NSAIDs).... pseudogout

Pseudohermaphroditism

A congenital abnormality in which the external genitalia resemble those of the opposite sex, but ovarian or testicular tissue is present as normal. A female pseudohermaphrodite may have an enlarged clitoris resembling a penis and enlarged labia resembling a scrotum. A male may have a very small penis and a divided

scrotum resembling labia. (See also hermaphroditism, sex determination.)... pseudohermaphroditism

Pseudomonas

Species of rod-like bacteria that live in soil and decomposing matter. PSEUDOMONA AERUGINOSA is capable of causing disease in humans and is present in pus from wounds.... pseudomonas

Psychodrama

An aid to psychotherapy in which the patient acts out certain roles or incidents.

Psychodrama is often carried out with a partner or in a group; music, dance, and mime are often used.... psychodrama

Psychogenic

A term for a symptom or disorder that is caused by psychological or emotional problems.... psychogenic

Psychopathology

The study of abnormal mental processes. There are 2 main approaches: the descriptive, which aims to record symptoms that make up a diagnosis of mental illness; and the psychoanalytic, which is concerned with the unconscious feelings and motives of the individual.... psychopathology

Psychopharmacology

The study of drugs that affect mental states, such as antipsychotic drugs, antidepressant drugs, and anti-anxiety drugs.... psychopharmacology

Pubes

The pubic hair or the area of the body covered by this hair.... pubes

Pulpectomy

The removal of the tooth pulp. It is part of root-canal treatment.... pulpectomy

Pulpotomy

Removal of the coronal part of the pulp of a tooth after it has become inflamed, usually by infection.

Infection is most often due to extensive tooth decay (see caries, dental) or dental fractures (see fracture, dental).

Pulpotomy prevents further degeneration of the pulp.

If treatment is unsuccessful, rootcanal treatment may be required.... pulpotomy

Purine

Any of a group of nitrogencontaining compounds synthesized in the body or produced by the digestion of certain proteins. Increased levels of purine can cause hyperuricaemia, which may lead to gout. Foods that have a high purine content include sardines, liver, kidneys, pulses, and poultry.... purine

Pyloroplasty

An operation in which the pylorus (the outlet from the stomach) is widened to allow free passage of food into the intestine.

Pyloroplasty may be performed as part of the surgery for a peptic ulcer, or to prevent tightening of the pyloric muscles after vagotomy.... pyloroplasty

Pyogenic Granuloma

A common, noncancerous skin tumour that develops on exposed areas after minor injury. It can be removed surgically, by electrocautery, or by cryosurgery.... pyogenic granuloma

Pyrogen

A substance that produces fever. The term is usually applied to proteins released by white blood cells in response to infections. The word is also sometimes used to refer to chemicals released by microorganisms.... pyrogen

Retinitis Pigmentosa

An inherited condition in which there is degeneration of the rods and cones of the retina at the back of both eyes.

The 1st symptoms appear during or after adolescence and include night blindness.

Tests show a ring-shaped area of blindness which, over some years, extends to destroy an increasing area of the visual field, though central vision is retained, often for many years.

Opthalmoscopy reveals several masses of black pigment corresponding to the areas of visual loss.

Affected individuals and their parents should have genetic counselling.... retinitis pigmentosa

Role-playing

The acting out of a role (the pattern of behaviour expected in a given situation).

The phrase “sick role” describes the type of passive behaviour expected and allowed of a patient; people with social or emotional problems may unconsciously adopt this role to gain sympathy and understanding.... role-playing

Salmon Patch

See stork mark.... salmon patch

Sleep Paralysis

The sensation of being unable to move at the moment of going to sleep or when waking up, usually lasting only a few seconds. It may be accompanied by hallucinations. Sleep paralysis most often occurs in people with narcolepsy. (See also cataplexy.)... sleep paralysis

Spastic Paralysis

Inability to move a part of the body, accompanied by rigidity of the muscles. Causes of spastic paralysis include stroke, cerebral palsy, and multiple sclerosis. (See also paralysis.)... spastic paralysis

Todd’s Paralysis

Weakness in part of the body following some types of epileptic seizure (see epilepsy).

The weakness may last for minutes, hours, or even days, but there is no lasting effect.

The cause is thought to be temporary damage to the motor cortex (the area of the brain that controls movement).... todd’s paralysis

Zona Pellucida

The thick, transparent, noncellular layer that surrounds a developing egg cell in the ovarian follicle. At fertilization, the zona pellucida is penetrated by at least 1 sperm.... zona pellucida

Pediculicide

n. an agent that kills lice; examples include *dimeticone, *malathion, and *permethrin.... pediculicide

Peptic

adj. 1. relating to pepsin. 2. relating to digestion.... peptic

Phon

n. a unit of loudness of sound. The intensity of a sound to be measured is compared by the human ear to a reference tone of 2 × 10?5 pascal sound pressure and 1000 hertz frequency. The intensity of the reference tone is increased until it appears to be equal in loudness to the sound being measured; the loudness of this sound in phons is then equal to the number of decibels by which the reference tone has had to be increased.... phon

Abies Pindrow

Royle.

Synonym: A. pindrow Spach. A. webbiana Lindl. var. pindrow Brandis. Pinus pindrow Royle.

Family: Pinaceae.

Habitat: Kashmir, Himachal Pradesh, Tehri-Garhwal and other areas of northern India, at altitudes of 2,100-3,600 m.

English: Pindrow-Fir, Silver-Fir, The West-Himalayan Low-Level Fir.

Ayurvedic: Taalisha (related sp.).

Folk: Badar, Morinda, Raisalla, Ransla.

Action: Uses similar to those of A. webbiana.

Terpenoids, flavonoids, glycosides and steroids of the leaf were found to have mast cell stabilizing action in rats. Terpenoids and flavonoids offered bronchoprotection against his- tamine challenge in guinea pigs. The ulcer protective action of petroleum ether, benzene and chloroform fraction has been attributed to steroidal contents. Terephthalic acid demethyl ester (TADE), isolated from the leaf, exhibited protection against inflammation and bronchospasm in guinea pigs. Ethanolic extract of leaves showed significant anxiolytic effects on all the paradigms of anxiety, barbiturate hypnosis potentiation.

Pindrolactone, a lanostane-based triterpene lactone, isolated from the leaves, showed mild activity against Gram-positive bacteria but exhibited potent antibacterial activity against Gram-negative bacteria E. coli.... abies pindrow

Abruptio Placenta

Placental bleeding after the 24th week of pregnancy, which may result in complete or partial detachment of the placenta from the wall of the womb. The woman may go into shock. The condition is sometimes associated with raised blood pressure and PRE-ECLAMPSIA. (See also PREGNANCY AND LABOUR.)... abruptio placenta

Abrus Precatorius

Linn.

Family: Papilionaceae; Fabaceae.

Habitat: Throughout the country, ascending to an altitude of about 1,050 m in the outer Himalayas.

English: Indian Wild Liquorice, Jequirity, Crab's Eye, Precatory Bean.

Ayurvedic: Gunjaa, Gunjaka, Chirihintikaa, Raktikaa, Chirmi- ti, Kakanti, Kabjaka, Tiktikaa, Kaakananti, Kaakchinchi. (Not to be used as a substitute for liquorice.)

Unani: Ghunghchi, Ghamchi.

Siddha/Tamil: Kunri.

Folk: Chirmiti, Ratti.

Action: Uterine stimulant, abortifa- cient, toxic. Seeds—teratogenic. A paste of seeds is applied on vitiligo patches.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India has indicated the use of seeds in baldness.

Seeds contain abrin, a toxalbumin, indole derivatives, anthocyanins, ste- rols, terpenes. Abrin causes agglutination of erythrocytes, haemolysis and enlargement of lymph glands. A non- toxic dose of abrin (1.25 mcg/kg body weight), isolated from the seeds of red var., exhibited a noticeable increase in antibody-forming cells, bone marrow cellularity and alpha-esterase-positive bone marrow cells.

Oral administration of agglutinins, isolated from the seeds, is useful in the treatment of hepatitis and AIDS.

The seed extract exhibited antischis- tosomal activity in male hamsters.

The methanolic extract of seeds inhibited the motility of human spermatozoa.

The roots contain precol, abrol, gly- cyrrhizin (1.5%) and alkaloids—abra- sine and precasine. The roots also contain triterpenoids—abruslactone A, methyl abrusgenate and abrusgenic acid.

Alkaloids/bases present in the roots are also present in leaves and stems.

A. fruticulosus Wall. Ex Wight and Arn. synonym A. pulchellus Wall., A. laevigatus E. May. (Shveta Gunjaa) is also used for the same medicinal purposes as A. precatorius.

Dosage: Detoxified seed—1-3 g powder. Root powder—3-6 g. (API Vols. I, II.)... abrus precatorius

Acacia Pennata

(L.) willd.

Family: Mimosaceae.

Habitat: Throughout India; ascending to 1,700 m in the Himalayas.

Ayurvedic: Lataakhadira, Aadaari, Ari.

Siddha/Tamil: Indan, Indu. Iyak Koluntu (tender leaves).

Folk: Aila.

Action: Bark—antibilious, antiasth- matic. Leaf—stomachic, styptic (for bleeding gum), antiseptic (for scalding of urine). A decoction of young leaves is taken for body pain, headache and fever.

The bark contains tannin 9%, lupe-ol and alpha-spinasterol. Stem yields sitosterol.... acacia pennata

Acanthaster Planci

The Crown-of-thorns starfish, known for the considerable damage that it may cause to coral reefs. It seems to occur in epidemics. The spines are venom-tipped, but usually the envenomation leads only to a painful spike wound which may sometimes get infected. Multiple spikes, either in one episode, or many individual stings rarely lead to systemic symptoms, but may lead to hypersensitivity.... acanthaster planci

Aconitum Palmatum

D. Don.

Synonym: A. bisma (Buch.-Ham.) Rapaics.... aconitum palmatum

Admitting Privileges

The authorization given by a health care organization’s governing body to medical practitioners and, in some cases, other professionals who request the privilege of admitting and/or treating patients. Privileges are based on a provider’s licence, training, experience and education.... admitting privileges

Adult Placement

A type of foster care in which an older person lives with an approved family.... adult placement

Advance Care Planning

Planning in advance for decisions that may have to be made prior to incapability or at the end of life. People may choose to do this planning formally, by means of advance directives, or informally, through discussions with family members, friends and health care and social service providers, or a combination of both methods.... advance care planning

Adenanthera Pavonina

Linn.

Adansonia digitata Linn.

Family: Bombacaceae.

Habitat: Native to tropical Africa; common along the west coast of India.

English: Baobab, Monkey Bread tree, African calabash.

Ayurvedic: Sheet-phala, Ravanaam- likaa, Gorakshi, Panchparni.

Unani: Gorakh Imli.

Siddha/Tamil: Papparapuli.

Folk: Gorakh Imli; Gorakh Chinchaa.

Action: Cooling, refrigerant (allays burning sensation). Leaves— diaphoretic (used as a prophylactic against fevers). Fruit—antidysen- teric, antiseptic, antihistaminic.

The fruit pulp is a source of vitamin C (175.0-445.4 mg/100 g); dried pulp contains calcium and vitamin B1. Furfural (9.6%) is obtained after distillation of the fruit. In Africa, dried leaves provide much of the dietary calcium. Aqueous extract of the bark is used for treating sickle cell anaemia.

An infusion of the leaves and flowers is given in respiratory disorders. (Powdered leaves prevented crisis in asthma induced by histamine in guinea pigs.) Dried fruit pulp also gives relief in bronchial asthma, allergic dermatitis and urticaria.

Family: Leguminosae; Mimosaceae.

Habitat: The western Ghats, the Andamans and sub-Himalayan tract; also cultivated.

English: Coral Wood, Red Wood.

Ayurvedic: Rakta Kanchana, Rakta Kambala.

Siddha/Tamil: Anai-gundumani.

Folk: Ghumchi (bigger var.).

Action: Astringent and styptic (used in diarrhoea, haemorrhage from the stomach, haematuria), anti-inflammatory (in rheumatic affections, gout). Seeds— anticephalgic; also used for the treatment of paralysis. A decoction is given in pulmonary affections.

The seed contains an anti-inflammatory active principle, O-acetyletha- nolamine. The leaves contain octa- cosanol, dulcitol, glucosides of beta- sitosterol and stigmasterol. The bark contains sitgmasterol glucoside.... adenanthera pavonina

Ageing / Aging In Place

Meeting the desire and ability of people, through the provision of appropriate services and assistance, to remain living relatively independently in the community in his or her current home or an appropriate level of housing. Ageing in place is designed to prevent or delay more traumatic moves to a dependent facility, such as a nursing home.... ageing / aging in place

Ageing Of The Population

See “population ageing”.... ageing of the population

Air Passages

These are the nose, pharynx or throat (the large cavity behind the nose and mouth), larynx, trachea or windpipe, and bronchi or bronchial tubes. On entering the nose, the air passes through a high narrow passage on each side, the outer wall of which has three projections (the nasal conchae). It then passes down into the pharynx where the food and air passages meet and cross. The larynx lies in front of the lower part of the pharynx and is the organ where the voice is produced (see VOICE AND SPEECH) by aid of the vocal cords. The opening between the cords is called the glottis, and shortly after passing this the air reaches the trachea or windpipe.

The windpipe leads into the chest and divides above the heart into two bronchi, one of which goes to each lung, in which it splits into ?ner and ?ner tubes (see LUNGS). The larynx is enclosed in two strong cartilages: the thyroid (of which the most projecting part, the Adam’s apple, is a prominent point on the front of the neck), and the cricoid (which can be felt as a hard ring about an inch below the thyroid). Beneath this, the trachea – which is sti?ened by rings of cartilage so that it is never closed, no matter what position the body is in – can be traced down until it disappears behind the breastbone.... air passages

Albizia Procera

Benth.

Family: Mimosaceae.

Habitat: All over India.

Ayurvedic: Shveta Shirisha (bark- white or greenish-white).

Action: Bark—a decoction is given in rheumatism and haemorrhage.

The bark contains beta-sitosterol and yields 12-17% tannins.

An oleanolic acid saponin, proceric acid saponin mixture from seeds and root saponin exhibit spermicidal activity.... albizia procera

All Payer System

A system in which prices for health services and payment methods are the same, regardless of who is paying. For instance, in an all payer system, federal or state government, a private insurer, a self-insured employer plan, an individual, or any other payer could pay the same rates. The uniform fee bars health care providers from shifting costs from one payer to another. See “cost shifting”.... all payer system

Allied Health Personnel

Specially trained and licensed (when necessary) people in occupations that support and supplement the functions of health professionals. For the older population, such health personnel may include home health workers and nursing assistants. See also “auxiliary worker”.... allied health personnel

Alpha-feto Protein

A protein produced in the gut and liver of the FETUS. Abnormality in the fetus, such as neural tube defect, may result in raised levels of alphafeto protein in the maternal blood. In DOWN’S (DOWN) SYNDROME, levels may be abnormally low. In either case, screening of the pregnancy should be carried out, including AMNIOCENTESIS to check the amount of alpha-feto protein in the amniotic ?uid. The protein may also be produced in some abnormal tissues in the adult – in patients with liver cancer, for example.... alpha-feto protein

Amyloid Plaques

Characteristic waxy deposits of amyloid found in primary AMYLOIDOSIS, the cause of which is unknown.... amyloid plaques

Alhagi Pseudalhagi

(Bieb.) Desv.

Synonym: A. camelorum Fisch. ex DC.

A. maurorum Medic.

Family: Papilionaceae; Fabaceae.

Habitat: The drier parts of Rajasthan, Gujarat, Punjab and Uttar Pradesh.

English: Camel Thorn, Persian Manna Plant.

Ayurvedic: Yavaasaka, Yavaasa, Yaasa, Duhsparshaa, Duraalab- haa, Kunaashak. Substitute for Dhanvayaasa. Yaasa-sharkaraa (Alhagi-manna).

Unani: Jawaansaa. Turanjabeen (Alhagi-manna).

Siddha/Tamil: Punaikanjuri, Kan- chori.

Action: Laxative, antibilious, diuretic, diaphoretic, expectorant. Leaves—used for fever, headache, rheumatism. Flowers—blood coagulant, used for piles. Alhagi- manna—expectorant, antiemetic, laxative.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of dried whole plant in gout and haemorrhagic disorders.

The aerial parts contain flavonoids, tannins, sterols, triterpenes, saponins and anthroquinones.

The proanthocyanidins derived from the plant possess hypolipidemic and antiatherosclerotic properties. The compounds prevented an increase in rat serum cholesterol and triglycerides, and they decreased the manifestation of atherosclerosis.

A polymeric proanthocyanidin, extracted from the plant, improved energy metabolism and increased the work capacity in rats.

Ethanolic extract of the aerial parts produced positive inotropic effect on rabbit heart.

Dosage: Whole plant—20-50 g for decoction. (API Vol. II.) Decoction—50-100 ml. (CCRAS.)... alhagi pseudalhagi

Allium Porrum

Linn.

Synonym: A. ameloprasum Hook. f. non Linn.

Family: Liliaceae, Alliaceae.

Habitat: Native to the Mediterranean region; cultivated in India.

English: Leek.

Folk: Vilaayati Piyaaz. Praan (Kashmir). Seemevangayam (Tamil Nadu).

Action: Expectorant; used as a substitute for garlic.

Leek is poor in volatile oil content in comparison with garlic, but it contains sufficient amounts of non-toxic sapo- nins, which perhaps give it expectorant properties.

The bulbs contain several thiosul- phinates, and also potentially anticar- cinogenic flavonoids, quercetin and kaempferol.... allium porrum

Amygdalus Persica

Linn.

Synonym: Prunus persica Batsch.

Family: Rosaceae.

Habitat: Native to China; cultivated in Himalayan regions; grows in tropical and semi-tropical regions and temperate climates.

English: Peach tree.

Ayurvedic: Aaruka.

Unani: Aaaduu, Khokh.

Action: Leaves and bark—expectorant (used in cough, whooping cough, and chronic bronchitis), sedative, stomachic, demulcent, antiscorbutic, diuretic. Fresh leaves—anthelmintic. Powder of leaves—styptic (externally). Fruit— stomachic, antiscorbutic.... amygdalus persica

Anacyclus Pyrethrum

DC.

Synonym: A. officinarum Hayne

Family: Compositae; Asteraceae.

Habitat: Native to the Mediterranean region; cultivated in Algeria.

English: Spanish, Pellitory, Pyrethrum Root.

Ayurvedic: Aakaarakarabha, Aakallaka, Aakulakrit, Agragraahi.

Unani: Aaqarqarhaa.

Siddha/Tamil: Akkiraakaaram.

Action: Stimulant, cordial, rubefa- cient.A gargle of infusion is prescribed for relaxed vulva. Root— used for toothache, rheumatic and neuralgic affections and rhinitis. Roots, along with the root of Witha- nia somnífera and Vitis vinifera, are used in epilepsy.

Along with other therapeutic applications, Ayurvedic Pharmacopoeia of India indicates the use of the root in sciatica, paralysis, hemiplegia and amenorrhoea.

The root contains anacycline, isobu- tylamide, inulin and a trace ofessential oil.

The local anaesthetic activity of the alcoholic (2%) extract of the root was found to be comparable to that of xy- locaine hydrochloride (2%) in dental patients.

Use of the drug in patients with insulin-dependent diabetes mellitus reduces the dose of insulin. It decreased the plasma glucose and serum cholesterol levels after oral administration for 3-6 weeks. (The plant is mixed with Helleborus nigar in a ratio of 1:3.) The plant extract inhibited tobacco-induced mutagenesis by 47.5% at a concentration of 1 mg/plate.

Dosage: Root—500 mg to 1 g powder. (CCRAS.)... anacyclus pyrethrum

Anaphylactoid Purpura

See HENOCH-SCHÖNLEIN PURPURA.... anaphylactoid purpura

Anís Pequeño

See Anís chiquito.... anís pequeño

Anna Perenna

(Latin) In mythology, a goddess who was the personification of the perennial year... anna perenna

Andrographis Panicultata

Wall. ex Nees

Family: Acanthaceae.

Habitat: Throughout India, from Himachal Pradesh to Assam and Mizoram, and all over southern India.

English: Creat.

Ayurvedic: Kaalmegha, Bhuunimba, Bhuuminimbaka, Vishwambharaa, Yavtikta, Kalpanaatha, Kiraata-tikta (var.).

Unani: Kiryaat.

Siddha/Tamil: Nilavembu.

Action: Hepatoprotective, cholin- ergic, antispasmodic, stomachic, anthelmintic, alterative, blood purifier, febrifuge. It acts well on the liver, promoting secretion of bile. Used in jaundice and torpid liver, flatulence and diarrhoea of children, colic, strangulation of intestines and splenomegaly; also for cold and upper respiratory tract infections.

Key application: As bitter tonic, febrifuge and hepatoprotective. (Indian Herbal Pharmacopoeia.)

Kaalmegha, officinal in IP, consists of dried leaves and tender shoots, which yield not less than 1% andro- grapholide on dry-weight basis.

Several active constituents have been identified from the leaf and rhizome, including andrographolide, deoxyan- drographolide and other diterpenes.

Andrographolide exhibited strong choleretic action when administered i.p. to rats. It induces increase in bile flow together with change in physical properties of bile secretion. It was found to be more potent than sily- marin.

Andrographolide was found to be almost devoid of antihepatitis-B virus surface antigen-like activity (when compared with picroliv.)

The leaf and stem extracts of Kaal- megha/andrographolide given s.c. or orally did not change blood sugar level of normal or diabetic rats.

Alcoholic extract of the plant exhibited antidiarrhoeal activity against E. coli enterotoxins in animal models.

Clinical evidence of effectiveness of andrographis in humans is limited to the common cold. Preliminary evidence suggests that it might increase antibody activity and phagocytosis by macrophages, and might have mast cell-stabilizing and antiallergy activity. (Natural Medicines Comprehensive Database, 2007.)

The herb is contraindicated inbleed- ing disorders, hypotension, as well as male and female sterility (exhibited infertility in laboratory animals).

Dosage: Whole plant—5-10 ml juice; 50-100 ml decotion; 1-3 g powder. (CCRAS.)... andrographis panicultata

Aphanamixis Polystachya

(Wall.) Parker.

Synonym: Amoora rohituka W. and A.

Family: Meliaceae.

Habitat: The sub-Himalayas tracts, Sikkim, Assam, Bengal, western Ghats and the Andamans.

Ayurvedic: Rohitaka, Daadima- chhada, Daadima-pushpaka, Plihaghna. Tecoma undulata G. Don., Bignoniaceae, is also equated with Rohitaka.

Siddha/Tamil: Malampuluvan.

Action: Bark—strongly astringent, used in the diseases of the liver and spleen, and for tumours, enlarged glands. Seed oil—used in muscular pains and rheumatism. All parts of the plant exhibit pesticidal activity. Seed extract—antibacterial, antifungal.

An aqueous extract of the bark, when injected i.p. in normal guinea pigs, showed reduction in absolute lymphocyte count and an increase in spleen weight. The bark appears to be an effective immunosuppressive drug similar to prednisolone.

The stembark contains a limonoid, ammorinin and a saponin, poriferas- terol-3-rhamnoside.... aphanamixis polystachya

Artificial Limbs And Other Parts

See PROSTHESIS.... artificial limbs and other parts

Aspirin Poisoning

ASPIRIN is a commonly available analgesic (see ANALGESICS) which is frequently taken in overdose. Clinical features of poisoning include nausea, vomiting, TINNITUS, ?ushing, sweating, HYPERVENTILATION, DEHYDRATION, deafness and acid-base and electrolyte disturbances (see ELECTROLYTES). In more severe cases individuals may be confused, drowsy and comatose. Rarely, renal failure (see KIDNEYS, DISEASES OF), PULMONARY OEDEMA or cardiovascular collapse occur. Severe toxicity may be delayed, as absorption of the drug may be prolonged due to the formation of drug concretions in the stomach. Treatment involves the repeated administration of activated CHARCOAL, monitoring of concentration of aspirin in the blood, and correction of acid-base and electrolyte imbalances. In more severely poisoned patients, enhanced excretion of the drug may be necessary by alkalinising the urine (by intravenous administration of sodium bicarbonate – see under SODIUM) or HAEMODIALYSIS.... aspirin poisoning

Assessment Appeal Process

A process that allows a person who has been assessed to dispute the assessment, and which provides for the assessment to be changed.... assessment appeal process

Atropine Poisoning

See ATROPINE; BELLADONNA POISONING.... atropine poisoning

Batoko Plum

Flacourtia inermis

Description: This shrub or small tree has dark green, alternate, simple leaves. Its fruits are bright red and contain six or more seeds.

Habitat and Distribution: This plant is a native of the Philippines but is widely cultivated for its fruit in other areas. It can be found in clearings and at the edges of the tropical rain forests of Africa and Asia.

Edible Parts: Eat the fruit raw or cooked.... batoko plum

Banana And Plantain

Musa species

Description: These are treelike plants with several large leaves at the top. Their flowers are borne in dense hanging clusters.

Habitat and Distribution: Look for bananas and plantains in open fields or margins of forests where they are grown as a crop. They grow in the humid tropics.

Edible Parts: Their fruits are edible raw or cooked. They may be boiled or baked. You can boil their flowers and eat them like a vegetable. You can cook and eat the rootstocks and leaf sheaths of many species. The center or “heart” or the plant is edible year-round, cooked or raw.

Other Uses: You can use the layers of the lower third of the plants to cover coals to roast food. You can also use their stumps to get water (see Chapter 6). You can use their leaves to wrap other foods for cooking or storage.... banana and plantain

Barleria Prionitis

Linn.

Family: Acanthaceae.

Habitat: Throughout the hotter parts of India. Also, commonly grown as a hedge plant in gardens.

English: Common Yellow Nail Dye Plant.

Ayurvedic: Sahachara, Baana, Kurantaka, Kuranta, Koranda, Korandaka, Shairiya, Pita-saireyaka

(yellow-flowered var.). Also equated with Vajradanti.

Unani: Piyaabaansaa.

Siddha/Tamil: Chemmulli.

Folk: Piyaabaasaa, Jhinti, Kat- saraiyaa.

Action: Leaf—juicegiveninstomach disorders, urinary affections; mixed with honey and given to children with fever and catarrh; leaf juice is applied to lacerated soles of feet in the rainy season, mixed with coconut oil for pimples. Leaves and flowering tops—diuretic. Bark—diaphoretic and expectorant. Roots—paste is applied over boils and glandular swellings. Plant (Vajradanti)—antidontalgic, used for bleeding gums in Indian medicine. Ash, obtained from the whole plant, mixed with honey, is given in bronchial asthma.

The Ayurvedic Pharmacopoeia of India recommends oil extract of the plant for arresting greying of hair.

The leaves and flowering tops are diuretic, rich in potassium salts. Leaves and stems showed presence of iridoid glucosides, barlerin and acetylbarlerin. Flowers gave the flavonoid glycoside, scutellarein-7-neohesperidoside. The presence of beta-sitosterol is reported in the plant.

In the south, Nila Sahachara is equated with Ecbolium linneanun Kurz. (known as Nilaambari), and Shveta Sa- hachara with Justica betonica Linn.

Ecbolium linneanun plant is used for gout and dysuria; the root is prescribed for jaundice.

Dosage: Whole plant—50-100 g for decoction. (API Vol. III.)... barleria prionitis

Basil Tea Has Anti-inflammatory Properties

Basil tea is an Ayurvedic natural remedy used to treat a wide variety of diseases such as asthma, diabetes and high cholesterol. Hindus worship the plant for its religious significance as well. Basil Tea description Basil, a plant from the mint family, is original from India and Asia. It is an aromatic herb with a strong fragrance being largely used in spaghetti sauces, stews and tomato recipes. Basil is a source of vitamins and other nutrients.  Studies showed that this herb has anti-bacterial and anti-inflammatory health properties, fighting against intestinal problems, headaches and ulcers, as well. In aromatherapy, basil is used to alleviate mental fatigue. Basil tea is the resulting beverage from brewing the abovementioned plant. Basil Tea brewing To prepare Basil tea:
  • bring the water and the basil leaves to boil (in a small tea pan)
  • lower the heat and allow it to brew for 3-4 minutes
  • add the tea leaves or tea bags and sugar according to taste
  • bring to boil
  • turn off the heat
  • strain it into cups and add milk according to taste
Basil Tea benefits Studies claimed that Basil Tea is successesfully used to:
  • treat intestinal colics, gastric ulcers and bloating/swelling of the abdomen
  • treat anorexia
  • fight urinary tract infections
  • help against diarrhea
  • help fight insomnia
  • help treat lesions and inflammations in the mouth
  • enhance the body’s ability to resist stress
  • help to relieve pain
Basil Tea side effects Basil tea side effects are generally associated to large intakes. There have been thus noticed:shallow breathing, blood in the urine or sputum, mouth and throat burns, nausea, racing heartbeat, seizures, dizziness and coma. Pregnant or breastfeeding women, as well as women trying to become pregnant should not use Basil tea. Basil tea has anti-inflammatory and anti-microbial properties, proving itself to be an important adjuvant in treating arthritis, fevers and other ailments. It is also constantly used to add savor to several dishes.... basil tea has anti-inflammatory properties

Benign Prostatic Hypertrophy, Or Hyperplasia

(BPH) The benign buildup in the prostate of “warts” or epithelial neoplasias that can block or interrupt urination, and which are usually concurrent with moderate prostate enlargement. They cause a dull ache on urination, ejaculation, and/or defecation. The diagnosis is medical, since the same subjective conditions can result from cancer of the prostate. BPH is common in men over fifty and can be the result either of diminished production of complete testosterone or poor pelvic circulation. Alcohol, coffee, speed, and antihistamines can all aggravate the problem.... benign prostatic hypertrophy, or hyperplasia

Birth Pool

A pool of warm water in which a woman can give birth to her baby. The infant is delivered into the water. The method was introduced during the 1980s and is claimed to make delivery less painful and upsetting.... birth pool

British Pharmacopoeia

See PHARMACOPOEIA.... british pharmacopoeia

Broncho-pneumonia

See PNEUMONIA.... broncho-pneumonia

Bauhinia Purpurea

Linn.

Habitat: The Himalayas, and distributed in Northern India, Assam, Khasi Hills. Also cultivated in gardens.

English: Camel's Foot tree, Pink Bauhinia, Butterfly tree, Geramium tree, Orchid tree.

Ayurvedic: Kovidaara, Rakta Kaanchanaara.

Unani/Siddha: Sivappu mandaarai.

Siddha: Mandarai.

Folk: Koilaara, Khairwaal, Kaliaar, Rakta Kanchan.

Action: Bark—astringent, antidiar- rhoeal. Flower buds and flowers, fried in purified butter, are given to patients suffering from dysentery. Extract of stems are used internally and externally for fractured bones. Plant is used in goitre. It exhibited antithyroid-like activity in experimental animals.

The flowers contain astragalin, iso- quercitrin and quercetin, also antho- cyanins. Seeds contain chalcone gly- cosides.... bauhinia purpurea

Belladonna Poisoning

Atropa belladonna (deadly nightshade) is a relatively rare plant and severe poisoning is not common. The berries, which are black, ripen from August to October and are the most commonly ingested part of the plant. However, all parts of the plant are toxic. The berries contain ATROPINE and other unidenti?ed ALKALOIDS, the leaves HYOSCINE and atropine, and the roots hyoscine. All these alkaloids have an ANTICHOLINERGIC e?ect which may cause a dry mouth, dilated pupils with blurred vision, TACHYCARDIA, HALLUCINATIONS and PYREXIA. There may also be ATAXIA, agitation, disorientation and confusion. In severe cases there may be CONVULSIONS, COMA, respiratory depression and ARRHYTHMIA. Clinical effects may be delayed in onset for up to 12 hours, and prolonged for several days. Treatment is supportive.... belladonna poisoning

Benefits Of Privet Tea

Privet tea has been known for its health benefits, especially related to liver and kidney problems. As an herbal tea, it is a good everyday drink which also helps you stay healthy. Find out more about it in this article! About Privet Tea Privet tea is made from privet, an herbal plant which grows all around the world. The privet is a semi-evergreen shrub which includes species of plants used as hedges in gardens. Some species can grow up to 20 meters tall. The plant has glossy, oppositely-arranged, dark green leaves; they can grow as long as 10-12cm. The flowers are small, white, fragrant and blooming in pinnacles. The fruits are purple-black drupes born in clusters; the fruits of some species can be poisonous to humans. How to prepare Privet Tea The fruit of the plant is used to make privet tea. To enjoy this tea, you need to add some dried privet fruit to a cup of freshly-boiled water. Let it steep for 5-7 minutes before you remove the dried fruit. Sweeten it with honey, if you want to. If not, your tea’s ready! You can also use granulated or powdered forms of the fruit in order to make privet tea. Privet Tea Benefits Privet tea has plenty of health benefits thanks to the active constituents which are transferred from the fruit of the herbal plant. Some of them include ligustrum, oleanolic acid, betulinic acid, ursolic acid, saponins and tannins. Drinking privet tea will help strengthen your immune system. Thanks to this, it is often recommended in the treatment for HIV, AIDS, and cancer. It is also often used in treating liver and kidney problems, as well as hepatitis, hypertension, Parkinson’s disease, and respiratory tract infections. Privet tea is also helpful when it comes to treating backaches, insomnia, palpitations, rheumatic pains, and tinnitus. You can use it if you’re feeling dizzy, tired or you’ve got blurred vision caused by stress. It also reduces the chances of getting grey hair, and helps you deal with premature menopause or general menopausal problems. Privet Tea Side Effects If you’re pregnant or breast feeding, you should stop drinking privet tea. Also, children with ages under 12 shouldn’t drink it either. Privet tea can worsen asthma symptoms to those already suffering from this disease. You should also avoid drinking it if you’ve got diarrhea. You should be careful with the amount of privet tea you drink: don’t drink more than 5-6 cups of tea a day. This counts for other types of tea, as well. If you drink too much, you might get some of these symptoms: headaches, dizziness, insomnia, diarrhea, vomiting, and loss of appetite. Privet tea has very few side effects, while it has plenty of important health benefits. It can be consumed every day with no worries.... benefits of privet tea

Bulbar Paralysis

See PARALYSIS; MOTOR NEURONE DISEASE (MND).... bulbar paralysis

Burl Palm

Corypha elata

Description: This tree may reach 18 meters in height. It has large, fan -shaped leaves up to 3 meters long and split into about 100 narrow segments. It bears flowers in huge dusters at the top of the tree. The tree dies after flowering.

Habitat and Distribution: This tree grows in coastal areas of the East Indies.

Edible Parts: The trunk contains starch that is edible raw. The very tip of the trunk is also edible raw or cooked. You can get large quantities of liquid by bruising the flowering stalk. The kernels of the nuts are edible.

CAUTION

The seed covering may cause dermatitis in some individuals.

Other Uses: You can use the leaves as weaving material.... burl palm

Benefits Of Muira Puama Tea

For a sweet tea, try the muira puama tea. As an herbal tea, it has many health benefits, especially for men. Read the article and find out more about the muira puama tea! About Muira Puama Tea The main ingredient of the muira puama tea is, of course, the muira puama herbal plant. It is a flowering plant with two species (Benth and Anselmino). Its origin can be found in the Amazonian rainforests, although at present it is grown in Europe, as well. The trees grow up to 4 meters, sometimes even taller. They have short-petioled leaves which are light green on upper surface and dark brown on lower surface. It has small, white flowers that have a similar scent to those of jasmine. How to prepare Muira Puama Tea In order to drink a cup of muira puama tea, pour boiling water in a cup that contains one teabag or a teaspoon of dried herbs. Cover the cup and let it steep for 2-4 minutes. Next, remove the teabag or tea herbs. If you want, you can add milk and honey to your cup of tea, to sweeten the taste. Muira Puama Iced Tea You can also enjoy muira puama tea during summertime, by preparing it as an iced tea. For 1 liter, you mainly need 5 teabags, 2 cups of boiling water, and a similar amount of cold water. Place the teabags into a teapot or a heat resistant pitcher, then pour the boiling water. Let it steep for about 5 minutes, while you fill a serving pitcher with cold water. Remove the tea bags and pour the tea into the serving pitcher. Add ice and more cold water to the serving pitcher. Sweeten it with honey, sugar or anything else that comes to your mind. Components of Muira Puama Tea Muira Puama tea’s components come from the herb with the same name. There are two medically active ones: long-chain fatty acids and alkaloid chemicals. Also, the bark and roots of the plant (which are used to make the tea) contain some of the following constituentsg: alpha-pinene, alpha-terpinene, beta-sitosterol, camphor, eugenol, imonene, linalool, stigmasterols, and various acids and essential oils. Muira Puama Tea Benefits The most important benefit of the muira puama tea is for men. After all, the muira puama herb is also known as the “Viagra of the Amazon”. That is because it helps with sexual impotence, by increasing the blood flow to the genital areas. It also helps in the treatment of male pattern baldness. Muira puama tea can be used as a tonic for nervous conditions and depressions. It is useful when it comes to improving one’s memory, especially among elders. The tea also increases your energy level, and improves mental focus and clarity. It is often used in the treatment for rheumatism and indigestion. It also helps women with treating the discomforts of menopause, as well as lessening the pain that comes with menstrual cramps. Muira Puama Tea side effects It is considered best to avoid drinking muira puama tea during pregnancy or when you are breast feeding. In both cases, it can affect the baby.The teaalsoincludes some enzymes which are harmful if you’re suffering from peptic ulcers. In this case, it is recommended that you not consume this type of tea. Consumption of muira puama tea can also lead to an increase in the blood pressure levels. For most people, it is only temporary, but it can be harmful for people with existing complications of blood pressure levels. If this is your case, it’s best that you consult your doctor first before you start drinking this tea. As muira puama acts as a stimulant, drinking too much muira puama tea may lead to anxiety and insomnia. It is generally advised that you not drink more than six cups of tea a day, no matter the type of tea. Other symptoms that you might get are headaches, loss of appetite, vomiting, diarrhea, dizziness, and irregular heartbeats.   Muira puama tea is clearly full of health benefits, especially for men. It is good for women, as well, as long as it is not consumed during pregnancy or breast feeding periods. Be careful not to get any side effects and you can enjoy this type of tea with no worries.... benefits of muira puama tea

Bidens Pilosa

Linn.

Family: Compositae; Asteraceae.

Habitat: Throughout India in gardens, waste places and tea plantations.

Folk: Phutium (Gujarat), Kuri (Garhwal).

Action: Plant—cytotoxic. Leaf— applied to ulcers and swollen glands.

The plant contains a number of poly- acetylenes which are toxic to bacteria, fungi and human fibroblast cells. Phenylheptatriyne is the major constituent of the leaves and stems.

B. pilosa Linn. var. minor (Blume) Sherff, synonym B. pilosa Linn. var. bi- pinnata Hook. f. in part, gave phytos- terin-B, which like insulin, showed hy- poglycaemic activity both in normal and diabetic rats. B. pilosa auct. non Linn., synonym B. chinensis Willd., is used for leprosy, fistulae, pustules, tumours.... bidens pilosa

Cardiac Pump

See HEART, ARTIFICIAL.... cardiac pump

Cardio-pulmonary Resuscitation

A combination of mouth to mouth resuscitation (E.A.R.) to oxygenate the blood, and external chest compression (E.C.C.) to compress the heart to help pump this artificially oxygenated blood around the body to maintain tissue oxygen concentration and prevent death.... cardio-pulmonary resuscitation

Care Package

A combination of services designed to meet a person’s assessed needs.... care package

Care Pathway

An agreed and explicit route an individual takes through health and social care services. Agreements between the various providers involved will typically cover the type of care and treatment, which professional will be involved and their level of skills, and where treatment or care will take place. See also “care plan”; “care programme”.... care pathway

Care Plan

A dynamic document based on an assessment which outlines the types and frequency of care services that a client receives. It may include strategies, interventions, continued evaluation and actions intended to help an older person to achieve or maintain goals.... care plan

Care Programme

A documented arrangement of integrated care, based on the analysed needs of a specific group of people, from intake to supply of care and services, as well as the intended outcomes, and including a description of the way the arrangement should be applied in order to match the needs of individual persons.... care programme

Benefits Of Pygeum Bark Tea

Try an herbal tea from Africa - pygeum bark tea. Despite its bitter, slightly unpleasant taste, this tea is becoming quite popular. It has plenty of health benefits which will surely help you stay healthy. Find out more about pygeum bark tea and give it a try! About Pygeum Bark Tea Pygeum bark tea is made from the bark of the pygeum tree, an evergreen tree which belongs to the rose family. It grows in central and southern Africa, although it has become endangered due to the large demands for the tree’s bark. A mature tree can be as tall as 25m. The bark is black-brown and scaly, with alternate, simple and long dark green leaves. The flowers bloom from October to May; they are androgynous and greenish-white. The fruit is red-brown, rather wide but not big (about 1cm) and has two lobs, with a seed in each one. The fruit can be used as food both for humans and animals. The wood can be used to make tools, or build homes. How to prepare Pygeum Bark Tea There are two ways in which you can make pygeum bark tea. One involves chopped bark; add it to a cup of freshly-boiled water and let it steep for 10-15 minutes. For the other, you can use the powdered form of the pygeum; you add it to a cup of boiled water, letting it steep for 3-5 minutes. Pygeum bark tea is known to be pretty bitter. If the taste is too much for you, sweeten it with milk, honey or fruit juice. Pygeum Bark Tea Benefits A few important active constituents that are transferred from the pygeum bark to the tea are: beta-sitosterol, ursolic acid, oleanic acid and ferulic acid. Pygeum bark tea can be drunk by men, as it has important health benefits for them. It is often added in the treatment for benign prostatic hyperplasia. It is also recommended in the case of male infertility, as it increases the quantity and quality of the sperm. It can even be used as an aphrodisiac, as it enhances the sexual performance. Pygeum bark tea is used to treat urinary tract infections (cystitis, prostatitis); it also increases the urinary function. You can drink pygeum bark tea if you’ve got symptoms of bronchitis, influenza, or various other respiratory infections. This tea will also help you if you’ve got a fever. An interesting benefit is related to hair: drinking pygeum bark tea is quite useful in the treatment for hair loss. The infusion can be applied on wet hair, after it’s been washed with shampoo. Try it if you’ve got these problems. Pygeum Bark Tea Side Effects If you’re pregnant or breast feeding, it is best not to drink pygeum bark tea; it can affect the baby in both cases. Also, it’s safer not to give it to children, either. It might neutralize the effects of various types of medication. Make sure you talk to your doctor first if you’re taking any kind of medication; he will tell you if it’s safe or not to drink pygeum bark tea. Also, drinking too much pygeum bark tea might not be good for you. It might lead to stomach discomfort, diarrhea, constipation, nausea, dizziness, headaches, or visual disturbances. Don’t let its bitter taste scare you - pygeum bark tea is good for your health. It is especially recommended for men, but it can be useful for women, as well.... benefits of pygeum bark tea

Black Dragon Pearl Tea

Black Dragon Pearl tea is a type of black tea that provides a full range of benefits to consumers of all ages, worldwide. It distinguishes itself through its chocolate taste and therapeutical benefits. Black Dragon Pearl Tea description Black Dragon Pearl tea, originating from the Chinese province Yunnan, is a type of unsteady black tea, well-known in the area. Each tea pearl contains thirty hand-picked leaves and buds which are immediately rolled to prevent leaves from drying. A morning or afternoon cup of Black Dragon Pearl tea together served with fruits may be a pleasant way to relax oneself. How to prepare Black Dragon Pearl Tea Black Dragon Pearl Black tea can be infused up to three times and still keeps its malty flavor. In case of steeping too long, like any black tea, it can get bitter. When brewed, it has a reddish-brown color, whose aroma makes it identifiable for the senses and, when drunk it has a very delicate and chocolaty taste. Black Dragon Pearl Black tea can be served with or without sugar (or honey) and milk. It contains a relatively low caffeine level. When preparing Black Dragon Pearl tea:
  • Use 1 teaspoon of tea for 8 ounces of water ( 2ounces of tea equals 25-30 teaspoons)
  • Heat water until it is almost boiling (195 degrees).
  • Pour over the pearls.
  • Steep them for 3 or 4 minutes.
Black Dragon Pearl Tea benefits Studies revealed the important qualities of Black Dragon Pearl tea. Like any type of black tea, this luxurious beverage contains antioxidants - proven adjuvants in treating cancer and stopping tumors growth. This type of tea has been associated to lowering the risk of stomach, colon and breast cancer, although the connection is not fully scientifically proven. Researchers claim that a compound in Black Dragon Pearl tea caused colorectal cancer cells to disappear, whereas normal cells were not affected by it. Black Dragon Pearl tea is also recommended in dealing with:
  • poor arterial functioning that can cause heart attacks and strokes
  • inflammation
  • viruses
  • cholesterol reduction
  • teeth decay
  • blood toxins removing
  • aging effects
Black Dragon Pearl Tea side effects In case of intaking more than 3 cups of tea per day, headaches and dizziness can sometimes appear. Rarely, symptoms of upset stomach may follow Black Dragon Pearl tea consumption. A diet based on Black Dragon Pearl tea plays an important part in one’s life because it renders the sufficient quantity of antioxidants needed by human body to fight against a large array of diseases.... black dragon pearl tea

Case Payment

Fixed cost for a case. See also “fee for service”.... case payment

Caudal Papillae

A group of sensory organs at the posterior end of some male nematodes (excluding “phasmids” which are situated on the lateral aspects of the tip of the tail); the number and arrangement of caudal papillae are used for identification of nematodes such as in Ascarididae and Thelaziidae.... caudal papillae

Cayratia Pedata

(Wall.) Gagnep.

Synonym: Vitispedata VahlexWall.

Family: Vitaceae.

Habitat: Bihar, West Bengal and Assam, up to 900 m.

Ayurvedic: Godhaapadi.

Siddha/Tamil: Kattuppirandai.

Action: Leaves—astringent and refrigerant (used for ulcers, diarrhoea, uterine and other fluxes).

Aerial parts—diuretic, spasmolytic.... cayratia pedata

Benefits Of The Pomegranate Tea

The pomegranate tea is a refreshing, fruity tea whose main ingredient is the pomegranate. The fruit itself is refreshing, sweet and a bit bitter. Not only doespomegranate tea taste lovely, but it is also good for your health! About the Pomegranate Tea The pomegranate tea is a delicious beverage, sweet and fruity-flavored. The main ingredient is, of course, the pomegranate. Pomegranate trees are cultivated all over Asia, as well as in California, Arizona, tropical Africa, and in the Mediterranean region of Southern Europe. In the Northern Hemisphere, they are harvested from September to February, and in the Southern Hemisphere, from March to May. As a fruit, the pomegranate has vitamin C, vitamin B5, potassium, natural phenols, and polyphenols. Also, the edible seeds contain fiber. How to prepare Pomegranate Tea It isn’t difficult to prepare pomegranate tea. First, boil 6-8 ounce of water. Pour the hot water in the cups which contain either tea leaves or teabags. Let it steep for about 10 minutes before you remove the tea leaves or the teabag. For a calming effect, you can try to combine the pomegranate tea with chamomile tea. You can also mix it with black or green teas, based on your taste. Pomegranate Ice Tea If you miss the taste of pomegranate tea, but you don’t feel like drinking it during summer, you can try pomegranate ice tea. It shouldn’t take you more than 10 minutes to prepare it. For 5 serves, you need the following ingredients: 5 cups of boiling water, 5 teabags (of a non-fruity kind of tea), 2 cups of pomegranate juice, and sugar. First, boil the water. Pour it into a heat-resistant pitcher, add the teabags and let it steep for about 10 minutes. Next, remove the teabags and let the temperature cool. Add the pomegranate juice and the sugar, stir well and then put it in the refrigerator. Later, serve it with ice. For a richer flavor, you can add lemon, lime or mint leaves.  Or experiment a little and add anything else you like and think it might make it taste better. Benefits of Pomegranate Tea Pomegranate as a fruit, consumed in all its forms, contains lots of health benefits. The pomegranate tea is no exception. Pomegranate tea is rich in antioxidants. They are helpful when it comes to fighting against aging. They also strengthen the immune system, and lower the risk of getting cancer and diabetes. Pomegranate tea can also help reduce blood pressure and bad cholesterol levels. The chances of getting cardiovascular diseases become lower if you drink pomegranate tea. Pomegranates also have anti-inflammatory properties. Drinking pomegranate tea can slow down joint conditions (osteoarthritis), as well as reduce the pain caused by joint conditions and diseases. It will also help you protect your body’s cartilage. Also, pomegranate tea can help with strengthening your immunity, reducing LDL (bad cholesterol), and treating depression and preserving a good mental balance. Side effects of Pomegranate Tea There aren’t really any bad side effects related to pomegranate as a fruit, as well as pomegranate tea. Although rare, there are cases of allergies to pomegranate. Also, pomegranate juice and, based on how much you drink, possibly pomegranate tea as well, may neutralize the positive effects of some medications; it’s best to check with your doctor. Other side effects are related to drinking too much pomegranate tea; this applies to all types of tea, as well. It is advised that you not drink more than 6 cups of tea a day. Otherwise, you might get the following symptoms: headaches, loss of appetite, vomiting, diarrhea, insomnia, dizziness, and irregular heartbeats. In this case, you need to try and drink less. Whether hot during winter, or cold during summer, pomegranate tea is a great choice for a fruity, refreshing beverage.  It also brings many health benefits with it. Give it a try and you’ll surely enjoy it!... benefits of the pomegranate tea

Cephalic Papillae

A group of sensory organs around the mouth opening (excluding amphids which are situated on the lateral aspects of the mouth); the number and arrangement of the cephalic papillae are significant for the classification of nematodes.... cephalic papillae

Chili Pepper

Fidelity, Hex Breaking, Love ... chili pepper

Cirrus Pore

The opening through which the cirrus is protruded.... cirrus pore

Cadillo Tres Pies

Gingerbush (Pavonia spinifex).

Plant Part Used: Leaf, root.

Dominican Medicinal Uses: The leaf and root are traditionally prepared as a tea by decoction and administered orally for disorders of the kidney, gallbladder or liver, blood in the urine, hepatitis, sexually transmitted infections, uterine fibroids, tumors, cysts and menopausal hot flashes.

Safety: Insufficient information identified.

Contraindications: Unknown; insufficient information identified in the available literature.

Drug Interactions: Unknown; insufficient information identified in the available literature.

Laboratory & Preclinical Data: The chloroform extract of the plant has shown antibacterial activity in vitro.

* See entry for Cadillo de gato in “Part 3: Dominican Medicinal Plant Profiles” of this book for more information, including references.... cadillo tres pies

Caesalpinia Pulcherrima

Sw.

Family: Caesalpiniaceae.

Habitat: Cultivated in gardens throughout India.

English: Barbados Pride, Peacock Flower.

Ayurvedic: Padangam, Ratnagandhi, Krishnachuudaa.

Siddha/Tamil: Mayirkonrai, Nalal.

Folk: Guleturaa, Sankeshwara.

Action: Leaves—laxative, antipyretic. Used in Eastern India as a substitute for senna. Dried and powdered leaves are used in erysipelas. Flowers—anthelmintic. Also used for cough and catarrh. Root—a decoction is prescribed in intermittent fevers. Bark— emmenagogue, abortifacient.

The plant contains a flavonoid, my- ricitroside. The leaves, flowers and fruits contain tannins, gums, resin, benzoic acid. Presence of cyanidin- 3,5-diglucoside is also reported from the flowers, hydrocyanic acid from the leaves. The root contains caesalpin type diterpenoids along with sitosterol.

The leaves have displayed anticancer activity in laboratory animals. A diter- penoid, isolated from the root, also showed anticancer activity.

In Pakistan, the leaf and flower extract exhibited activity against Grampositive bacteria.... caesalpinia pulcherrima

Cirrus Pouch

A hollow organ surrounding the inverted cirrus.... cirrus pouch

Clinical Pathway

A multidisciplinary set of daily prescriptions and outcome targets for managing the overall care of a specific type of patient, e.g. from pre-admission to post-discharge for patients receiving inpatient care. Clinical pathways are often intended to maintain or improve quality of care and decrease costs for patients in particular diagnosis-related groups.... clinical pathway

Clinical Performance Measure

An instrument that estimates the extent to which a health care provider delivers clinical services that are appropriate for each patient’s condition; provides them safely, competently and in an appropriate time-frame; and achieves desired outcomes in terms of those aspects of patient health and patient satisfaction that can be affected by clinical services.... clinical performance measure

California Poppy Tea Against Insomnia

California Poppy tea is a natural remedy against insomnia. It is largely used for its healing properties against anxiety, too. California Poppy Tea description California poppy is an annual or perennial plant, originating from the Pacific coast. Its orange-yellow flowers flourish during spring and midsummer. North Americans used to consume this plant for stress-caused illnesses. Landscape artists appreciate California poppy plant for its beauty. California Poppy tea is the beverage resulting from brewing the abovementioned plant. California Poppy Tea brewing To prepare California Poppy tea, place the flowers, stems and leaves in boiling water for about 10 minutes. California Poppy Tea benefits California Poppy tea has been successfully used to:
  • fight insomnia by ushering in restful sleep
  • fight anxiety
  • fight headaches
  • fight toothaches and stomachaches
  • fight skin sores and ulcers
California Poppy Tea side effects Pregnant women and children should not consume California Poppy tea. California Poppy tea is a healthy beverage able to deal with a large array of diseases such as stomachaches and ulcers and it also proved to be helpful for skin sores.... california poppy tea against insomnia

Calotropis Procera

(Ait.) R.Br.

Family: Asclepiadaceae.

Habitat: An evergreen shrub distributed in West and Central India.

English: Swallow-Wart, Milk Weed, (purple-flowered), King's Crown.

Ayurvedic: Alarka, Surya, Su- uryaahvya, Vikirna, Vasuka, Tapana, Tuulaphala, Kshirparna, Arkaparna, Aasphota.

Unani: Aakh, Madaar, Ashar.

Siddha/Tamil: Vellerukku, Erukku.

Action: The plant is used against bronchial asthma (especially flowers with black pepper). Leaves—used for treating chronic cases of dyspepsia, flatulence, constipation and mucus in stool. Seed oil— geriatric and tonic. Leaves, flowers and root-bark oil—antimicrobial (maximum activity in leaves). The Ayurvedic Pharmacopoeia of India indicated the use of the root and leaf in asthma and dyspnoea; stem bark in diseases of the spleen.

Root bark contains benzoylline- olone and benzolisolineolone. Root, stem and leaves, also latex contain beta-amyrin. Flowers contain evanidin 3-rhamnoglucoside. The plant contains a cardenolide, proceragenin, an antibacterial principle.

The latex is given for treating epilepsy, also in painful, joints and swellings. The latex exhibited anti-inflammatory activity in carrageenan-and formalin- induced rat paw oedema model.

The herb can alter menstrual cycle and temporarily inhibit ovulation. Cardiac glycosides may be additive when combined with Digoxin. (Sharon M. Herr.)

Dosage: Leaf—250-750 mg powder; root—1-3 g for decoction (API Vol. I); stem bark—0.5-1 g powder (API Vol. III). Milky juice—500 mg to 1 g (CCRAS.)

Action: Anti-inflammatory. Root— hypocholesterolaemic. Poisonous to human beings in mature stages.

The flowers contain flavonoids, 7- rhamnosides, 3-glucosides and 3-glu- co-7-rhamnosides of kaempferol and quercetin. Roots gave triterpenoid glycosides, which decreased serum cholesterol and total protein and increased blood sugar equivalent to bu- tadione in rats.

EtOH (50%) extract of the plant exhibits CNS depressant and hypotensive activity in rat.... calotropis procera

Canthium Parviflorum

Lam.

Synonym: Plectronia parviflora (Lam.) Bedd.

Family: Rubiaceae.

Habitat: Throughout the Deccan Peninsula, from Gujarat and Maharashtra southwards, and in Bihar and Orissa.

English: Wild Jasmine.

Folk: Kaari.

Siddha/Tamil: Karai, Kadan Karai, Nalla Karai, Kudiram.

Action: Leaves and fruits— astringent, antispasmodic; used against cough. A decoction of the root and leaves is given in flu. Bark—antidysenteric.

The plant contains mannitol (0.5%) and alkaloids. Canthium umbellatum Wight is also known as Kaari.... canthium parviflorum

Clinical Practice Guideline

A systematically developed statement to assist practitioner and patient decisions about appropriate health care for one or more specific clinical circumstances.... clinical practice guideline

Co-payment

The specified portion (cost amount or percentage) that health insurance, or a service programme, may require a person to pay towards his or her medical bills or services.... co-payment

Cold Packs

An excellent analgesic treatment for the skin pain of many envenomations, especially those of jellyfish stings. It is usually less effective than heat for the treatment of stonefish, stingray and other venomous-spined fish envenomations.... cold packs

Coma Position

See RECOVERY POSITION and APPENDIX 1: BASIC FIRST AID.... coma position

Community Physician

A doctor who works in the specialty that encompasses PREVENTIVE MEDICINE, EPIDEMIOLOGY and PUBLIC HEALTH.... community physician

Community-based Care / Community-based Services / Programmes

The blend of health and social services provided to an individual or family in his/her place of residence for the purpose of promoting, maintaining or restoring health or minimizing the effects of illness and disability. These services are usually designed to help older people remain independent and in their own homes. They can include senior centres, transportation, delivered meals or congregate meals sites, visiting nurses or home health aides, adult day care and homemaker services.... community-based care / community-based services / programmes

Capsella Bursa-pastoris

(Linn.) Moench.

Family: Cruciferae; Brassicaceae.

Habitat: Throughout India as a weed in cultivated areas and waste places, particularly in the temperate regions up to an altitude of 4,200 m.

English: Shepherd's Purse, St. James's Wort.

Folk: Mumiri.

Action: The herb or its juice extracts are employed to check menorrhagia and haemorrhages from renal and genitourinary tract. Also used in diarrhoea and dysentery and as a diuretic.

Key application: In symptom-based treatment of mild menorrhagia and metrorrhagia. (German Commission E.) The British Herbal Pharmacopoeia reported antihaem- orrhagic action.

Aerial parts contain flavonoids, polypeptides, choline, acetylcholine, histamine and tyramine.

The extract of dried or green plant causes strong contraction of the small intestines and uterus of guinea pigs. A quarternary ammonium salt has been isolated from the herb which is reported to be responsible for its pharmacological activity.

Young leaves contain vitamin A (5,000 IU/100 g) and ascorbic acid (91 mg/100 g); among other constituents are hesperidin and rutin, which reduced permeability of blood vessel walls in white mice. A neoplasm inhibitory substance has been identified as fumaric acid. An inhibitory effect of the extracts of the herb on Ehrlich solid tumour in mice was found to be due to the fumaric acid.

Major constituent of the essential oil is camphor.... capsella bursa-pastoris

Cardiac Pacemaker

The natural pacemaker is the sinuatrial node, found at the base of the heart. The heart normally controls its rate and rhythm; heart block occurs when impulses cannot reach all parts of the heart. This may lead to ARRHYTHMIA, or even cause the heart to stop (see HEART, DISEASES OF). Arti?cial pacemakers may then be used; in the United Kingdom these are required for around one person in every 2,000 of the population. Usually powered by mercury or lithium batteries, and lasting up to 15 years, they are either ?xed to the outside of the chest or implanted in the armpit, and connected by a wire passing through a vein in the neck to the heart. Normally adjusted to deliver 65–75 impulses a minute, they also ensure a regular cardiac rhythm. Patients with pacemakers may be given a driving licence provided that their vehicle is not likely to be a source of danger to the public, and that they are receiving adequate and regular medical supervision from a cardiologist.

Although there are numerous possible sources of electrical interference with pacemakers, the overall risks are slight. Potential sources include anti-theft devices, airport weapon detectors, surgical diathermy, ultrasound, and short-wave heat treatment. Nevertheless, many pacemaker patients lead active and ful?lling lives.... cardiac pacemaker

Carica Papaya

Linn.

Family: Caricaceae.

Habitat: Native to West Indies and Central America; now cultivated in Uttar Pradesh, Punjab, Rajasthan, Gujarat, Maharashtra and South India.

English: Papaya, Papaw.

Ayurvedic: Erand-karkati, Papitaa.

Unani: Papitaa Desi.

Siddha/Tamil: Pappaali, Pappayi.

Action: Ripe fruit—stomachic, digestive, carminative, diuretic, galactagogue. Useful in bleeding piles, haemoptysis, dysentery and chronic diarrhoea. Seeds— emmengagogue, abortifacient, vermifuge. Juice of seeds is administered in enlarged liver and spleen, and in bleeding piles.

Key application: Papain, the enzyme mixture extracted from raw papain (latex of Carica papaya), has been included among unapproved herbs by German Commission E. Experiment-based as well as clinical research indicate that papain may be effective (in the treatment of inflammations) in high doses (daily dose 1500 mg corresponding to 2520 FIP units).

Unripe fruit—emmengagogue and abortifacient. Latex—applied topically on eczema, ringworm, psoriasis, corns, warts, sloughing wounds, carbuncles and eschar of burns.

Green parts of the plant and seed contain an alkaloid carpaine. Seeds also contain carpasemine.

Latex contain enzymes—papain and chymopapain and alkaloids carpaine and pseudocarpaine. A proteinaceous material from latex showed anticoagulant activity; in higher doses it is heart depressant and as a spasmogen on smooth muscle of guinea pig ileum. An alkaloid solution showed depressant action on heart, blood pressure and intestine.

The anthelmintic action of seeds against Ascaris lumbricoides is due to carpasemine.

Papain, an enzyme mixture prepared from the fruit, seeds and leaf, hydrolyses polypeptides, amides and esters, particularly when used in an alkaline environment, and is used in digestive disorders.

Papain inhibits platelet aggregation, which may further increase the risk of bleeding in patients also taking anticoagulants. Concurrent administration of cyclophosphamide with papain caused sever damage to lung tissues in rats. (Sharon M. Herr.)

Chymopapin C is an immunosup- pressive enzyme from plant extract. Carpaine, extracted from the plant, exhibited anti-tubercular activity, also antitumour in vitro, and hypotensive.

Dosage: Leaf—40-80 ml infusion; latex—3-6 g (CCRAS.)... carica papaya

Congregate Meals Programme

Delivery of meals and socialization activities to older adults in a designated location.... congregate meals programme

Corrigan’s Pulse

The name applied to the collapsing pulse found with incompetence of the heart’s aortic valve. It is so-called after Sir Dominic John Corrigan (1802–80), the famous Dublin physician, who ?rst described it.... corrigan’s pulse

Cascara Sagrada Tea - A Powerful Laxative

Cascara Sagrada Tea has been known since ancient times as a great stimulant and laxative agent. In fact, the ones to discover its medical benefits were the American. The first proofs of this fact date from the 17th century, when American practitioners used Cascara Sagrada bark to treat many bacterial ailments of the digestive system. Cascara is a small shrub that grows mainly in the North America, in states like Idaho, California or Montana. Cascara never grows taller than 50 centimeters and has pale yellow greenish leaves and deep green leaves. Also known as rhamnus purshiana, Cascara has purple fruits or black berries that hide usually three hard seeds. Cascara Sagrada is harvested in the fall and can only be used dried (one year apart from the harvesting time) in order to release its curative benefits. Many people in Northern America specialize in Cascara Sagrada harvesting and herb processing (the plant needs to be properly dried and according to a list of specifications). Cascara Sagrada Tea Properties Cascara Sagrada Tea is known for its strong, stimulant and laxative properties. The main substances of this tea are very efficient in cases of nervous system failures and intestinal tract ailments. Cascara Sagrada Tea has a very bitter and therefore unpleasant taste. That’s why most people prefer to take it as capsules or extracts. Cascara Sagrada Tea Benefits Aside from its use as a constipation treatment, Cascara Sagrada Tea can also cure a variety of diseases involving the digestive tract, such as intestinal parasites or bacterial infections. However, make sure that you take this tea responsibly and don’t forget that this is a medical treatment wich only should be taking while you’re sick. Don’t try to replace your morning coffee with Cascara Sagrada Tea or you’ll face a series of complications! How to make Cascara Sagrada Tea Infusion When preparing Cascara Sagrada Tea, you have to make sure that you only use ingredients from a trusted provider. Nowadays, there are many illegal substances on the market sold as tea. Also, the herb you bought may be exactly what the label says it is, but not properly dried, in which case you’ll suffer from unwanted complications as well. Once you have the right ingredients, use a teaspoon of dried herbs for every cup of tea you want to make, add boiling water and wait 20 minutes for the wonderful benefits to be released. Strain the decoction and drink it hot or cold. You may also add honey or even sugar if the taste feels a bit unpleasant. Cascara Sagrada Tea Side Effects When taken in small amounts, Cascara Sagrada Tea is a safe treatment. However, high dosages may lead to various problems, such as urine discoloration, blood in stools, pain and vomiting. Make sure the dosage you’re using is the appropriate one or ask your doctor before making any moves: it’s better to be safe than sorry! Cascara Sagrada Contraindications Cascara Sagrada Tea is not recommended for pregnant or breastfeeding women, patients suffering from appendicitis or ulcerative colitis. Also, if you are on blood thinners or anticoagulants, avoid taking a treatment based on Cascara Sagrada Tea. To gather more information, talk to an herbalist or to your doctor! If he gives you the green light and you happen to be in a teashop, add Cascara Sagrada Tea to your shopping cart and enjoy its wonderful benefits responsibly!... cascara sagrada tea - a powerful laxative

Ceiba Pentandra

(Linn.) Gaertn.

Synonym: Eriodendron anafractuo- sum DC.

Family: Bombacaceae.

Habitat: West and South India. Often found planted around villages and temples.

English: Kapok, White Silk Cotton.

Ayurvedic: Kuuta-Shaalmali, Shveta Shaalmali.

Siddha/Tamil: Ielavum (Tamil).

Action: Gum—laxative, astringent, demulcent (given in painful micturition). Unripe fruit—astringent. Root—diuretic, antidiabetic, an- tispasmodic (used in dysentery). Flowers—laxative; used in lochi- orrhoea. Unripe pods—used in vertigo and migraine. Seed oil— used in rheumatism.

The plant contains linarin (acacetin 7-rutinoside). Seeds contain fatty acids, diglycerides and phospholipids. Leaves are considered a good source of iron and calcium. Stem-bark extract—antimicrobial.... ceiba pentandra

Cough, Paroxysmal

Attacks of uncontrollable coughing or “whooping”, often relating to whooping cough or bronchiectasis, but they can also be caused by the smoke from burning plastics and (memories of yesteryear) hash oil.... cough, paroxysmal

Country Health Programming

A managerial process dealing directly with the selection of priority health problems, specification of operational objectives and translation of these into activities, resource needs and organization.... country health programming

Critical Pathway

A treatment protocol based on a consensus of clinicians that includes only those few vital components or items proved to affect patient outcomes, either by the omission or commission of the treatment or the timing of the intervention.... critical pathway

Dillenia Pentagyna

Roxb.

Family: Dilleniaceae.

Habitat: The Himalayan terai from Punjab to Assam, and South India and the Andamans.

Folk: Dillenia. Agai (Bihar), Agachi (Maharashtra).

Action: See D. indica.

The bark contains 6% tannin.... dillenia pentagyna

Celastrus Paniculatus

Willd.

Family: Celastraceae.

Habitat: Sub-Himalayan tract up to 2,000 m and South Indian hills.

English: Staff tree, Intellect tree.

Ayurvedic: Jyotishmati, Paaraavat- padi. Kangunikaa, Kanguni, Vegaa, Maalkaanguni, Svarnalatikaa, Kaakaandaki, Katuveekaa.

Unani: Maalkangani.

Siddha/Tamil: Vaaluluvai.

Action: Seeds—nervine and brain tonic, diaphoretic, febrifugal, emetic. Seed-oil—used for treating mental depression, hysteria and for improving memory; also used for scabies, eczema, wounds, rheumatic pains, paralysis. A decoction of seeds is given in gout, rheumatism, paralysis and for treating leprosy and other skin diseases. Leaves— antidysenteric, emmenagogue. Root—a paste of root-bark is applied to swollen veins and pneumonic affections.

Key application: As a tranquilizer (Indian Herbal Pharmacopoeia) and brain tonic (The Ayurvedic Pharmacopoeia of India). The Ayurvedic Pharmacopoeia of India indicated the use of ripe seed in leucoderma and vitiligo.

The seeds are reported to contain the alkaloids, celastrine and paniculatine, which are the active principles of the drug.

In experimental animals, the drug showed lowering of leptazol toxicity, motor activity and amphetamine toxi- city, and raising the capacity for learning process. It showed significant CNS depressant effect and a clear synergism with pentobarbital. The seed extract showed hypolipidaemic effect and prevented atherogenesis in rabbits.

The seed oil showed tranquillizing effect and hastened the process of learning in experimental animals. It produced fall in blood pressure in anaesthetized dog, depressed the heart of frog, and was found to be toxic to rats.

In addition to the seed, 70% alcoholic extract of the plant showed sedative, anti-inflammatory and antipyretic, anti-ulcerogenic effect in experimental animals.

Methanolic extract of flowers showed both analgesic and anti- inflammatory activities experimentally.

Dosage: Ripe seed, devoid of capsule wall—1-2 g; oil—5-15 drops. (API Vol. II.)... celastrus paniculatus

Direct Patient Care

Any activities by a health professional involving direct interaction, treatment, administration of medications or other therapy or involvement with a patient.... direct patient care

Disability Postponement

Measures that can be initiated among those with a disease, usually a chronic disease, to lessen or delay the impact of disability from that disease, e.g. averting renal complications among those with diabetes.... disability postponement

Discharge Planning

A process by which an admitted inpatient’s needs on discharge are anticipated, planned for or arranged.... discharge planning

Disease Prevention

See “prevention”.... disease prevention

Doronicum Pardalianches

Linn.

Family: Compositae; Asteraceae.

Habitat: Native to Europe.

Unani: Daarunaj Aqrabi.

Action: Used in nervous depression, melancholia and as a constituent of cardiac tonic preparations.

The plant contains photoactive thio- phenes, in amounts reported to be toxic. Roots and aerial parts yield sesquiterpene alcohol, paralianchol and its aetophenone derivatives.... doronicum pardalianches

Chaga Tea Has Anti-cancer Properties

Chaga tea is a medicinal beverage with anti-inflammatory and anti-cancer properties. It is also an adjuvant in the liver treatment. Chaga Tea description Chaga is an irregularly-shaped polypore fungus (a mushroom), mainly found on the wounds of birch trees, on elm trees, alder trees and ironwood trees. This mushroom has a brown color, its veins being white or cream. It is acknowledged to hold less water than other types of mushrooms. In North Europe and Russia, the chaga mushroom has been used for a long period of time as a popular medicine remedy. Scientists have demonstrated that chaga has anti-cancer, anti-inflammatory, antiviral and immune-stimulating actions. It could also be used to relieve pain. Changa tea is the resulting beverage from brewing the abovementioned mushroom. Chaga Tea brewing Chaga tea is prepared in the following way:
  • shred the Chaga mushrooms
  • soften the pieces in cold water for about five hours
  • get the softened mushrooms out
  • save the liquid
  • add heated water to the softened mushrooms
  • let the mixture stand for about 2 days
  • mix the resultant Chaga tea with the saved liquid from the softening process
  • drink it slowly
Chaga tea may be consumed three times a day. Chaga Tea benefits Chaga tea has been successfully used to:
  • boost and strengthen the immune system
  • help in the treatment of various stomach diseases
  • help in expelling intestinal worms
  • help in the treatment of liver problems
  • help in the treatment of certain heart ailments, including hypertension
  • help in fighting tumors and lowering the risk of certain cancers (like breast, liver, uterus and stomach cancers)
  • help in the treatment of diabetes
  • act against HIV
  • treat inflammations
Chaga Tea side effects Before drinking Chaga tea, consult a health care provider. Chaga tea is a natural beverage used as a treatment for diabetes, several heart ailments as well as for inflammations.... chaga tea has anti-cancer properties

Chrozophora Plicata

Hook. f.

Synonym: C. rottleri Klotzsh.

Family: Euphorbiaceae.

Habitat: Throughout India except Jammu & Kashmir and northeastern India as a weed.

Ayurvedic: Suuryaavart.

Folk: Nilakanthi.

Action: Ash of root—bechic. Leaf— depurative. Seed—cathartic.

Roots contain xanthone glycosides and a chromone glycoside. Seeds gave oil rich in linoleate. The plant contains 9.0% tannin.... chrozophora plicata

Cissampelos Pareira

Linn.

Family: Menispermaceae.

Habitat: The tropical and subtropical parts of India.

English: Velvet-Leaf Pareira, Pareira Brava.

Ayurvedic: Paathaa, Ambashthaa, Varatiktaaa, Vriki, Aviddhakarni, Piluphalaa, Shreyashi.Bigger var., Raaja Paathaa, is equated with Stephania hernandifolia Walp.)

Unani: Paathaa.

Siddha/Tamil: Paadakkizhangu, Appatta.

Action: Root astringent, an- tispasmodic (used for cramps, painful menstruation), analgesic, antipyretic, diuretic, antilithic and emmenagogue. Prescribed for diarrhoea, dysentery, piles, urogenital affections (cystitis, nephritis, menorrhagia) Root paste is applied topically on scabies and eruptions on the body. Also used for preventing miscarriage.

The Ayurvedic Pharmacopoeia ofIn- dia attributed blood purifying properties to the root and indicated it in lactal disorders.

Hayatine (dl-beberine) is the principal alkaloid of the root. Its derivatives, methiodide and methochloride are reported to be potent neuromus- cular-blocking agents.

Not to be confused with Abuta grandiflora, a South American medicinal plant.

Dosage: Root—3-6 g powder. (API Vol. I.) the plant hastens fracture-healing by reducing the total convalescent period by 33% in experimental rats and dogs; it aids in recovery of the strength of the bones up to 90% in 6 weeks.

Dosage: Stem—10-20 ml juice. (API Vol. III.)... cissampelos pareira

Drug Product

A finished dosage form, for eg., a tablet, capsule or solution that contains a drug substance... drug product

Durable Power Of Attorney (enduring Power Of Attorney)

A written legal document in which a person appoints another individual to act as his/her agent for the purposes of health care decision-making in the event that he/she is unable or unwilling to make such decisions. See also “advance directive”.... durable power of attorney (enduring power of attorney)

Duranta Plumieri

Jacq.

Synonym: Duranta repens Linn.

Family: Verbenaceae.

Habitat: Cultivated as a hedge plant.

Folk: Durantaa.

Action: Antifungal (topically).

The leaves contain a saponin and fruits an alkaloid analogous to narco- tine. Macerated fruits, which even in dilutions of 1 : 100 parts of water, is lethal to mosquito larvae (the action is less marked on Culicine larvae.... duranta plumieri

Enduring Power Of Attorney

See “durable power of attorney”.... enduring power of attorney

Epidemic Polyarthritis

Disease common in Australia and caused by the Ross River Virus, an arbovirus transmitted by mosquitoes.... epidemic polyarthritis

Erb’s Paralysis

Erb’s paralysis is a form of paralysis of the arm due to stretching or tearing of the ?bres of the brachial nerve plexus. Such damage to the brachial plexus may occur during birth, especially when the baby is unusually large, and it is found that the arm lies by the side of the body with elbow extended, forearm pronated, and the ?ngers ?exed. The infant is unable to raise the arm.... erb’s paralysis

Chronic Obstructive Pulmonary Disease (copd)

This is a term encompassing chronic BRONCHITIS, EMPHYSEMA, and chronic ASTHMA where the air?ow into the lungs is obstructed.

Chronic bronchitis is typi?ed by chronic productive cough for at least three months in two successive years (provided other causes such as TUBERCULOSIS, lung cancer and chronic heart failure have been excluded). The characteristics of emphysema are abnormal and permanent enlargement of the airspaces (alveoli) at the furthermost parts of the lung tissue. Rupture of alveoli occurs, resulting in the creation of air spaces with a gradual breakdown in the lung’s ability to oxygenate the blood and remove carbon dioxide from it (see LUNGS). Asthma results in in?ammation of the airways with the lining of the BRONCHIOLES becoming hypersensitive, causing them to constrict. The obstruction may spontaneously improve or do so in response to bronchodilator drugs. If an asthmatic patient’s airway-obstruction is characterised by incomplete reversibility, he or she is deemed to have a form of COPD called asthmatic bronchitis; sufferers from this disorder cannot always be readily distinguished from those people who have chronic bronchitis and/ or emphysema. Symptoms and signs of emphysema, chronic bronchitis and asthmatic bronchitis overlap, making it di?cult sometimes to make a precise diagnosis. Patients with completely reversible air?ow obstruction without the features of chronic bronchitis or emphysema, however, are considered to be suffering from asthma but not from COPD.

The incidence of COPD has been increasing, as has the death rate. In the UK around 30,000 people with COPD die annually and the disorder makes up 10 per cent of all admissions to hospital medical wards, making it a serious cause of illness and disability. The prevalence, incidence and mortality rates increase with age, and more men than women have the disorder, which is also more common in those who are socially disadvantaged.

Causes The most important cause of COPD is cigarette smoking, though only 15 per cent of smokers are likely to develop clinically signi?cant symptoms of the disorder. Smoking is believed to cause persistent airway in?ammation and upset the normal metabolic activity in the lung. Exposure to chemical impurities and dust in the atmosphere may also cause COPD.

Signs and symptoms Most patients develop in?ammation of the airways, excessive growth of mucus-secreting glands in the airways, and changes to other cells in the airways. The result is that mucus is transported less e?ectively along the airways to eventual evacuation as sputum. Small airways become obstructed and the alveoli lose their elasticity. COPD usually starts with repeated attacks of productive cough, commonly following winter colds; these attacks progressively worsen and eventually the patient develops a permanent cough. Recurrent respiratory infections, breathlessness on exertion, wheezing and tightness of the chest follow. Bloodstained and/or infected sputum are also indicative of established disease. Among the symptoms and signs of patients with advanced obstruction of air?ow in the lungs are:

RHONCHI (abnormal musical sounds heard through a STETHOSCOPE when the patient breathes out).

marked indrawing of the muscles between the ribs and development of a barrel-shaped chest.

loss of weight.

CYANOSIS in which the skin develops a blue tinge because of reduced oxygenation of blood in the blood vessels in the skin.

bounding pulse with changes in heart rhythm.

OEDEMA of the legs and arms.

decreasing mobility.

Some patients with COPD have increased ventilation of the alveoli in their lungs, but the levels of oxygen and carbon dioxide are normal so their skin colour is normal. They are, however, breathless so are dubbed ‘pink pu?ers’. Other patients have reduced alveolar ventilation which lowers their oxygen levels causing cyanosis; they also develop COR PULMONALE, a form of heart failure, and become oedematous, so are called ‘blue bloaters’.

Investigations include various tests of lung function, including the patient’s response to bronchodilator drugs. Exercise tests may help, but radiological assessment is not usually of great diagnostic value in the early stages of the disorder.

Treatment depends on how far COPD has progressed. Smoking must be stopped – also an essential preventive step in healthy individuals. Early stages are treated with bronchodilator drugs to relieve breathing symptoms. The next stage is to introduce steroids (given by inhalation). If symptoms worsen, physiotherapy – breathing exercises and postural drainage – is valuable and annual vaccination against INFLUENZA is strongly advised. If the patient develops breathlessness on mild exertion, has cyanosis, wheezing and permanent cough and tends to HYPERVENTILATION, then oxygen therapy should be considered. Antibiotic treatment is necessary if overt infection of the lungs develops.

Complications Sometimes rupture of the pulmonary bullae (thin-walled airspaces produced by the breakdown of the walls of the alveoli) may cause PNEUMOTHORAX and also exert pressure on functioning lung tissue. Respiratory failure and failure of the right side of the heart (which controls blood supply to the lungs), known as cor pulmonale, are late complications in patients whose primary problem is emphysema.

Prognosis This is related to age and to the extent of the patient’s response to bronchodilator drugs. Patients with COPD who develop raised pressure in the heart/lung circulation and subsequent heart failure (cor pulmonale) have a bad prognosis.... chronic obstructive pulmonary disease (copd)

Ergot Poisoning

Ergot poisoning, or ergotism, occasionally results from eating bread made from rye infected with the fungus, Claviceps purpurea. Several terrible epidemics (St Anthony’s Fire), characterised by intense pain and hallucinations, occurred in France and Germany during the Middle Ages (see ERYSIPELAS). Its symptoms are the occurrence of spasmodic muscular contractions, and the gradual production of gangrene in parts like the ?ngers, toes and tips of the ears because of constriction of blood vessels and therefore the blood supply.... ergot poisoning

Erycibe Paniculata

Roxb.

Family: Convolvulaceae.

Habitat: Throughout India, common in Uttar Pradesh.

Ayurvedic: Ashoka-rohini (non- classical).

Siddha/Tamil: Unamkodi.

Action: Bark—anticholerin. Ripe fruit eaten in constipation. Pounded root prescribed internally in fever. Bark is used in cholera.

EtOH (50%) extract of aerial parts exhibit diuretic and hypotensive activity.... erycibe paniculata

Eulophia Pratensis

Lindl.

Synonym: E. ramentaceae Lindl. ex Wt.

Family: Orchidaceae.

Habitat: Pasture lands of Deccan from Konkan southwards.

English: Salep (var.).

Folk: Sataavari (Maharashtra).

Action: Tuber—used for scrofulous glands.... eulophia pratensis

Citrus Paradisi

Macf.

Family: Rutaceae.

Habitat: Khasi Hills, submountain- ous Himalayan ranges in Garhwal, Kumaon in U.P., Maland areas of South, Pachmarhi (Madhya Pradesh), Sikkim and Western Ghats.

English: Citron.

Ayurvedic: Maatulunga, Lunga, Maatulaka, Mahaalunga, Bijpuura, Bijaahva.

Unani: Turanj.

Siddha/Tamil: Kadaranrathai, Naarthankai, Thurinjippazham.

Folk: Bijoraa.

Action: Fruit—antiscorbutic, refrigerant, astringent, carminative, stomachic, antibacterial. Used for dyspepsia, bilious vomiting, cold, fever, hiccough. Root— anthelmintic. Flowers and buds— astringent.

The peel contains coumarins, limet- tin, scoparone, scopoletin and um- belliferon; besides nobiletin, limonin,

Family: Rutaceae.

Habitat: Native to the West Indies. Commercialized in the USA. Cultivated mainly in Punjab.

English: Grapefruit, 'Marsh' Grapefruit.

Folk: Chakotraa. Chima Bombili- maas (Tamil Nadu).

Action: Young leaves—decoction is used to relieve cold or headache. Fruit—used for developing resistance against colds and influenza.

Grapefruit is rich in vitamins, minerals, potassium and pectin, which balance the acid reaction in the stomach and stimulate appetite. Half grapefruit contains vitamin A 318 IU, vitamin C 46.8 mg, niacin 0.2 mg, potassium 158 mg. The fruit contains beta- carotene and cartenoid lycopene. Ly- copene is especially noted for reducing the risk of prostate cancer. The fruit juice contains furanocoumarins, including bergamottin, also naringin, naringenin, limonin, quercetin, kaem- pferol and obacunone.

For drug interactions with grapefruit juice, see Natural Medicines Comprehensive Database, 2007.

Grapefruit is not to be confused with grape (Vitis vinifera).... citrus paradisi

Clausena Pentaphylla

(Roxb.) DC.

Family: Rutaceae.

Habitat: The sub-Himalayan tract from Garhwal to Sikkim; also in Chakrata range.

Folk: Ratanjot (var.), Rowana. Surasi is a doubtful synonym.

Action: Bark—anti-inflammatory, spasmolytic; used in veterinary medicine for wounds and sprains.

Aerial parts contain coumarins— clausmarins A and B. Coumarins exhibit spasmolytic activity. The root also contains coumarins. Root and stem bark of Clausena excavata Burm. f. Eastern sub-Himalayan tract, Orissa and Bihar) also contain coumarins— clausenin and clausenidin. The root bark exhibits antibacterial activity against both Gram-positive and Gramnegative bacteria.

A related species, C. anisata (Willd.) Oliver, is reported from Uttar Pradesh. Ethanolic extract of the aerial parts exhibited spasmolytic activity. The fu- ranocoumarins, anisolactone, xantho- toxol, indicolactone, imperatorin and 2', 3'-epoxy-anisolactone have been isolated from the extract.

In West African traditional medicine, the decoction of the root is given to control convulsions in children. The anticonvulsant agent has been found to be heliettin, extracted from the stem bark and roots.... clausena pentaphylla

Claviceps Purpurea

(Fr.) Tul.

Family: Hypocreaceae.

Habitat: A fungous parasite on a number of grasses particularly in rye, cultivated in the Nilgiris and at Chakrohi farm in Jammu.

English: Ergot of Rye. Fungus of Rye.

Ayurvedic: Annamaya, Sraavikaa.

Unani: Argot.

Siddha/Tamil: Ergot.

Action: Uterine stimulant. Oxy- tocic, abortifacient, parturient, vasoconstrictor, haemostatic. Used in obstetrics (difficult childbirth, for exciting uterine contractions in the final stages of parturition). Also used after abortion for removal of the placenta. It is no more employed in internal haemorrhages, as it has been found to raise blood pressure in pulmonary and cerebral haemorrhage. Included among unapproved herbs by German Commission E.

The fungus gave indole alkaloids. The ergometrine or ergonovine group includes ergometrine and ergometri- nine. The ergotamine group includes ergotamine and ergotaminine. The er- gotoxine group includes ergocristine, ergocristinine, ergocryptine, ergo- cryptinine, ergocornine and ergo- corninine. The fungus also contains histamine, tyramine and other amines, sterols and acetylcholine.

The alkaloids of ergot are being used independently (not as a herbal medicine). Ergotamine is used to relieve migrainous headaches as it is a vasoconstrictor and has antisero- tonin activity. Ergometrine is used after childbirth in the third stage of labour and for post-partum haemorrhage, as it is a powerful uterine stimulant, particularly of the puerperal uterus. (Both the constituents are used under medical supervision). Er- gocornine significantly inhibited the development of induced mammary tumours in rats. The derivatives of ergot alkaloids are known to have suppressing effect on human breast cancer in initial stages. This activity is linked to prolactin inhibitory action.

The extract is toxic at 1.0-3.9 g, ergot alkaloids at 1 g in adults, 12 mg in infants. (Francis Brinker).

Dosage: Whole plant—10-30 ml infusion. (CCRAS.)... claviceps purpurea

Euphorbia Pilosa

Linn.

Family: Euphorbiaceae.

Habitat: Western Himalayas from Garhwal, westwards to Kashmir.

Ayurvedic: Saatala, Saptalaa. (Substitute).

Action: Purgative, emetic. Root— used in fistulous sores.

Prostratin, isolated from the roots of var. cornigeria Hook. f., was found to be pro-inflammatory.... euphorbia pilosa

Excretory Pore

An opening of the excretory system, normally situated on the ventral side at the anterior part of the body (e.g. in trematode miracidia).... excretory pore

Clerodendrum Phlomidis

Linn.f.

Synonym: C. multiflorum (Burm. f.) O. Kuntze.

Family: Verbenaceae.

Habitat: Throughout India, in the drier parts.

Ayurvedic: Agnimantha, Tarkaari, Vikraantaa, Jayanti, Jai, Jayaa, Ganikaarikaa, Vaijayanti, Bigger var. is equated with Premna integri- folia Linn., Shriparni, Naadeyi.

Siddha/Tamil: Tazhuthaazhai.

Folk: Laghu Arni.

Action: Plant parts used in dyspepsia, stomachache, colic, cholera, dysentery, postnatal fever, during convalscence from measles. Root and bark—bitter tonic, used in debility and nervous disorders.

The Ayurvedic Pharmacopoeia of India indicated the use of root in dysuria and retention of urine.

Flavonoids, scutellarein and pec- tolinarin, have been isolated from the leaves. Stems gave d-mannitol, beta- sitosterol, its glucosides and ceryl alcohol. The roots contain ceryl alcohol, clerodin, clerosterol and clerodendrin A.

The ethanolic extract of leaves exhibited hepatoprotective activity. The aqueous extract of leaves exhibited in vitro anthelmintic activity. The plant also exhibited antidiabetic activity.

Dosage: Root—12-24 g for decoction. (API Vol. III.)... clerodendrum phlomidis

Clinical Psychology

Psychology is the scienti?c study of behaviour. It may be applied in various settings including education, industry and health care. Clinical psychology is concerned with the practical application of research ?ndings in the ?elds of physical and mental health. Training in clinical psychology involves a degree in psychology followed by postgraduate training. Clinical psychologists are speci?cally skilled in applying theoretical models and objective methods of observation and measurement, and in therapeutic interventions aimed at changing patients’ dysfunctional behaviour, including thoughts and feelings as well as actions. Dysfunctional behaviour is explained in terms of normal processes and modi?ed by applying principles of normal learning, adaption and social interaction.

Clinical psychologists are involved in health care in the following ways: (1) Assessment of thoughts, emotions and behaviour using standardised methods. (2) Treatment based on theoretical models and scienti?c evidence about behaviour change. Behaviour change is considered when it contributes to physical, psychological or social functioning. (3) Consultation with other health-care professionals about problems concerning emotions, thinking and behaviour. (4) Research on a wide variety of topics including the relationship between stress, psychological functioning and disease; the aetiology of problem behaviours; methods and theories of behaviour change. (5) Teaching other professionals about normal and dysfunctional behaviour, emotions and functioning.

Clinical psychologists may specialise in work in particular branches of patient care, including surgery, psychiatry, geriatrics, paediatrics, mental handicap, obstetrics and gynaecology, cardiology, neurology, general practice and physical rehabilitation. Whilst the focus of their work is frequently the patient, at times it may encompass the behaviour of the health-care professionals.... clinical psychology

Communicable Period

The time or times during which the infectious agent may be transferred directly or indirectlyfrom an infected person to another person, from an infected animal to human, or from an infected human to an animal, including arthropods. In diseases such as diphtheria and scarlet fever, in which mucous membranes are involved from the first entry of the pathogen, the period of communicability is from the date of first exposure to a source of infection until the infective microorganism is no longer disseminated from the involved mucous membranes, ie, from the period before the prodromata until termination of a carrier stage, if this develops. Most diseases are not communicable during the earlyincubation period or after full recovery. In diseases transmitted by arthropods, such as malaria and yellow fever, the periods of communicability are those during which the infectious agent occurs in infective form in the blood or other tissues of the infected person in sufficient numbers to permit vector infections. A period of communicability is also to be distinguished for the arthropod vector - namely, that time during which the agent is present in the tissues of the arthropod in such form and locus (infective stage) as to be transmissible.... communicable period

Extrasensory Perception (esp)

An alleged way of perceiving current events (clairvoyance), future events (precognition) or the thoughts of other people (telepathy). ESP has never been scienti?cally proven and does not involve the use of any known senses.... extrasensory perception (esp)

Extrauterine Pregnancy

See ECTOPIC PREGNANCY.... extrauterine pregnancy

Family Practice

A form of specialty practice in which medical practitioners provide continuing comprehensive primary care within the context of the family unit.... family practice

For Profit

Organization or company in which profits are distributed to shareholders or private owners.... for profit

Frail Older Person

An older person in need of a substantial level of care and support.... frail older person

Glucose-6-phosphate Dehydrogenase

An ENZYME that performs an essential function in the metabolism of CARBOHYDRATE. A de?ciency in this enzyme – acronym G6PD – results in the breakdown of ERYTHROCYTES (HAEMOLYSIS), usually in the presence of oxidants (see OXIDANT) such as infections or drugs. The de?ciency disorder is a hereditary condition in which the enzyme is absent. The condition, characterised by pallor, rigors and pain in the loin, is divided into African, European (including FAVISM) and Oriental types. Sufferers should avoid substances that trigger haemolysis. Acute episodes are best treated symptomatically.... glucose-6-phosphate dehydrogenase

Computer-generated Prescriptions

The Royal College of General Practitioners has issued guidelines on the use of computer-generated prescriptions for drugs other than controlled drugs. The guidelines include rules on giving the patient’s name, address and date of birth with the responsible prescribing doctor’s name at the bottom, along with his or her surgery address and telephone number. The prescription has to be signed by the doctor. Several other requirements are included to minimise the risk of prescription-tampering, fraud or the inclusion of identi?able con?dential information. Full details of the guidelines appear in the British National Formulary, published every six months.... computer-generated prescriptions

Convolvulus Pluricaulis

Choisy.

Synonym: C. Microphyllus Sieb. C. Prostratus Forsk

Family: Convolvulaceae.

Habitat: Throughout India, Ascending To 2,000 M In The Himalayas.

Ayurvedic: Shankhapushpi, Shankhaahvaa, Kshirapushpi, Maangalya Kusuma (White- Flowered). Blue-Flowered Var., Vishnukraanti, Vishnukraantaa, Vishnugandhi Is Equated With Evolvulus Alsinoides Linn.

Unani: Sankhaahuli (Blue-Flowered)

Siddha/Tamil: Sivakraandi (White- Flowered), Vishnukraandi (Blue- Flowered).

Action: Plant—Brain Tonic, Tranquilizer Used In Nervine Disorders, Mental Aberration, Anxiety Neurosis, Internal Haemorrhages, Spermatorrhoea. Also Astringent, Antidysenteric, Antispasmodic, Antiphlogistic, Febrifuge, Alterative. Flowers—Styptic, Used For Uterine Bleeding. Leaf—Antiasthmatic, Used In Chronic Bronchitis. Root— Used In Gastric And Duodenal Ulcers, Uterine Affections And For Promoting Fertility.

The Ayurvedic Pharmacopoeia Of India Recommends The Plant For Epilepsy. The Plant Contains Sankhpushpine Alkaloids.

The Alcoholic (50%) Extract Of The Plant, When Administered To Rats (Through Gastric Intubation At Different Intervals), Has Shown Enhanced Neuropeptide Synthesis Of The Brain. It Induces An Increase In Brain Protein Content And Increases Acquisition Efficiency.

Evolvulus Alsinoides Contains Pen- Tatriacontane, Triacontane And Beta- Sitosterol.

Shankhapushpi Syrup (A Compound Containing C. Pluricaulis, Centella Asiatica, Nardostachys Jatamansi, Nepeta Hindostana, Nepeta Elliptica And Onos- Ma Bracteatum), When Administered With Phenytoin, A Modern Antiepilep- Tic Drug, Reduced Not Only Antiepileptic Activity Of Phenytoin But Also Lowered Plasma Phenytoin Levels.

Dosage: Whole Plant—3-6 G Powder. (Api Vol. III.)... convolvulus pluricaulis

Cucumis Prophetarum

Linn.

Synonym: C. myriocarpus Naud.

Family: Cucurbitaceae.

Habitat: Wild on wastelands of Sindh, Baluchistan, Rajasthan; in dry districts of Bellary in the South.

English: Wild Cucumber.

Ayurvedic: Indravarruni (var.).

Folk: Khar-indraayana.

Action: Emetic, purgative. Toxic.

Fruit pulp—a bitter resinous body, myriocarpin, produces nausea and is slightly purgative.

The fruit contain cucurbitacin B,C,D and Q1, and propheterosterol and its acetate. Cucurbitacin Q1 is an anti- tumour agent. Amino acids from the fruits are leucine, iso-leucine, pheny- lalanine, valine, tryptophan, tyrosine, proline, alanine threonine, glycine, arginine, crystine and aspartic acid.... cucumis prophetarum

Cucurbita Pepo

Linn.

Family: Cucurbitaceae.

Habitat: Native to N. Mexico and eastern U.S.A. Now commonly cultivated in Northern India.

English: Pumpkin, Marrow.

Unani: Safed Kaddu, Kumhraa.

Siddha: Suraikayi (Tamil).

Action: See C. maxima.

Key application: Seeds—in irritated bladder condition, micturition problems of benign prostatic hyperplasia stages 1 and 2. (German Commission E, The British Herbal Pharmacopoeia.) In childhood enuresis noctruna. (Expanded Commission E.)

The roasted and fresh seeds yield 32.2 and 38.0% of fatty oil respectively. The oil filled capsules were administered to patients suffering from hypertrophy of the prostate. Results showed that the frequent urge to urinate decreased and the urine residues were minimized.

The oil consists of the glycerides of linoleic 45, oleic 25, palmitic and stearic acids 30%. Sterols have been isolated.... cucurbita pepo

Glucose-6-phosphate-dehydrogenase (g6pd) Deficiency

A deficiency in the enzyme G6PD resulting in a haemolytic anaemia. This haemoglobinopathy contraindicates the use of the 4-aminoquinolines such as primaquine for the radical treatment of benign tertian and ovale tertian malaria.... glucose-6-phosphate-dehydrogenase (g6pd) deficiency

Good Medical Practice

Guidelines for doctors on the provision of good medical care laid down by the GENERAL MEDICAL COUNCIL (GMC).... good medical practice

Grace Period

A period past the due date of an insurance premium, during which coverage may not be cancelled.... grace period

Grains Of Paradise

Lust, Luck, Love, Money, Wishes ... grains of paradise

Cyanide Poisoning

Cyanide inhibits cellular RESPIRATION by binding rapidly and reversibly with the ENZYME, cytochrome oxidase. E?ects of poisoning are due to tissue HYPOXIA. Cyanide is toxic by inhalation, ingestion and prolonged skin contact, and acts extremely quickly once absorbed. Following inhalation of hydrogen cyanide gas, death can occur within minutes. Ingestion of inorganic cyanide salts may produce symptoms within 10 minutes, again proceeding rapidly to death. On a full stomach, effects may be delayed for an hour or more. Signs of cyanide poisoning are headache, dizziness, vomiting, weakness, ATAXIA, HYPERVENTILATION, DYSPNOEA, HYPOTENSION and collapse. Loss of vision and hearing may occur, then COMA and CONVULSIONS. Other features include cardiac ARRHYTHMIA and PULMONARY OEDEMA. Patients may have a lactic ACIDOSIS. Their arterial oxygen tension is likely to be normal, but their venous oxygen tension high and similar to that of arterial blood.

Treatment Administration of oxygen when available is the most important ?rst-aid management. Rescuers should be trained, must not put themselves at risk, and should use protective clothing and breathing apparatus. In unconscious victims, establish a clear airway and give 100 per cent oxygen. If breathing stops and oxygen is unavailable, initiate expired-air resuscitation. If cyanide salts were ingested, mouth-to-mouth contact must be avoided and a mask with a one-way valve employed instead. Some commercially available ?rst-aid kits contain AMYL NITRATE as an antidote which may be employed if oxygen is unavailable.

Once in hospital, or if a trained physician is on the scene, then antidotes may be administered. There are several di?erent intravenous antidotes that may be used either alone or in combination. In mild to moderate cases, sodium thiosulphate is usually given. In more severe cases either dicobalt edetate or sodium nitrite may be used, followed by sodium thio-sulphate. Some of these (e.g. dicobalt edetate) should be given only where diagnosis is certain, otherwise serious adverse reations or toxicity due to the antidotes may occur.... cyanide poisoning

Data Protection Act 1998

This legislation puts into e?ect the UK European Directive 95/46/EC on the processing of personal data, whether paper or computer records. The Act is based on eight principles, the ?rst of which stipulates that ‘personal data shall be processed fairly and lawfully’. Unfortunately this phrase is open to di?erent interpretations. Clari?cation is required to determine how the common-law duty of con?dentiality affects the health services in the context of using data obtained from patients for research work, especially epidemiological studies (see EPIDEMIOLOGY). Health authorities, trusts and primary care groups in the NHS have appointed ‘Caldicott guardians’ – named after a review of information that identi?es patients. A prime responsibility of the guardians is to agree and review internal protocols for the protection and use of identi?able information obtained from patients. The uncertainties over the interpretation of the legislation require clari?cation, but some experts have suggested a workable solution: to protect patients’ rights, researchers should ensure that data are fully anonymised whenever possible; they should also agree their project design with those responsible for data protection well in advance of its planned starting date. (See ETHICS.)... data protection act 1998

Date Palm

Phoenix dactylifera

Description: The date palm is a tall, unbranched tree with a crown of huge, compound leaves. Its fruit is yellow when ripe.

Habitat and Distribution: This tree grows in arid semitropical regions. It is native to North Africa and the Middle East but has been planted in the arid semitropics in other parts of the world.

Edible Parts: Its fruit is edible fresh but is very bitter if eaten before it is ripe. You can dry the fruits in the sun and preserve them for a long time.

Other Uses: The trunks provide valuable building material in desert regions where few other treelike plants are found. The leaves are durable and you can use them for thatching and as weaving material. The base of the leaves resembles coarse cloth that you can use for scrubbing and cleaning.... date palm

Didymocarpus Pedicellata

R.Br.

Synonym: D. macrophylla auct. non-Wall. ex D. Don.

Family: Gesneriaceae.

Habitat: Sub-tropical Himalaya from Himachal Pradesh to Aruna- chal Pradesh at 500-2,500 m.

Ayurvedic: Kshudra-Paashaana- bheda, Shilaa-valkaa, Shilaa- pushpa.

Action: Leaf—antilithic. Used for stones in kidney and bladder.

The leaves contain a number of chal- cones, quinochalcones and flavanones. Pediflavone has also been isolated from young leaves.... didymocarpus pedicellata

Guiding Principle

A general rule that can be used as a guide, for example, to develop and implement policies, to set up a managerial process or to organize primary health care in communities.... guiding principle

Health Personnel

All persons employed or contracted to provide health services.... health personnel

Health Planning

Planning for the improvement of the health of a population or community, for a particular population, type of health service, institution or health programme.... health planning

Health Policy

A formal statement or procedure within an institution (notably government) which defines goals, priorities and the parameters for action in response to health needs, within the context of available resources.... health policy

Health Programme

An organized series of activities directed towards the attainment of defined health objectives and targets.... health programme

Digitalis Purpurea

Linn.

Family: Scrophulariaceae.

Habitat: Native to West Europe. Cultivated in Tangmarg and Kishtawar in Kashmir, Darjeeling and the Nilgiris.

English: Digitalis, Foxglove.

Ayurvedic: Hritpatri, Tilapushpi (non-classical). (Purple var.)

Action: Main source of digoxin for the pharmaceutical industry. Digitalis glycosides increase the force of contraction of heart without increasing the oxygen consumption and slow the heart rate when auricular fibrillation is present. To be used only under strict medical supervision.

Not used as a herbal drug.... digitalis purpurea

Dioscorea Pentaphylla

Linn.

Synonym: D. triphylla var. doemona Prain & Burkill.

Family: Dioscoreaceae.

Habitat: Native to tropical Asia; distributed throughout India.

Ayurvedic: Vaaraahikanda (var., dry pieces are sold as Vidaarikanda).

Folk: Kaantaalu.

Action: Tubers contain 71.0780.77% carbohydrates, 8.68-15.93% albuminoids. Tubers are used to disperse swellings.... dioscorea pentaphylla

Dioscorea Prazeri

Prain & Burkill.

Synonym: D. Clarkei Prain & Burkill D. deltoidea Wall. var. sikkimensis Prain

Family: Dioscoreaceae.

Habitat: The Himalaya from Nepal to Bhutan, up to 1,500 m, also in Naga Hills.

Ayurvedic: Neelaalu.

Action: Tuber—antiphthiriac.

The rhizomes are used as a hair wash for killing lice. They contain diogenin (on dry basis) 2.5%. Also obtained are steroidal sapogenins, sito- sterol glucoside, prazerigenin-A gluco- side, prazerigenin-A bioside and 9,10- dihydrophenanthrenes.... dioscorea prazeri

Disabled Persons

Disabled persons in the United Kingdom have a range of services and ?nancial support available to help them to lead as normal and active a life as possible. O?cially, the disabled include those with signi?cant impairment of any kind, including impairment of sight and hearing, learning diffculties, and chronic illness as well as disablement due to accidents and the like.

Social services are provided by local-authority social-services departments. They include: practical help in the home (usually through home helps or aids to daily living); assistance in taking advantage of available educational facilities; help with adaptations to the disabled person’s house; provision of meals (‘Meals on Wheels’ or luncheon centres); and help in obtaining a telephone. Many of these facilities will involve the disabled person in some expense, but full details can be obtained from the local social-services department which will, if necessary, send a social worker to discuss the matter in the disabled person’s home. Owing to lack of funds and sta?, many local-authority social-services departments are unable to provide the full range of services.

Aids to daily living There is now a wide range of aids for the disabled. Full details and addresses of local o?ces can be obtained from: Disabled Living Foundation and British Red Cross.

Aids to mobility and transport Some car manufacturers make specially equipped or adapted cars, and some have o?cial systems for discounts. Details can be obtained from local dealers. Help can also be obtained from Motability, which provides advice.... disabled persons

Dracontium Polyphyllum

Linn.

Family: Liliaceae.

Habitat: Native to East Africa and Saudi Arabia.

English: Dragon's Blood.

Ayurvedic: Khoonkharaabaa, Heeraadokhi.

Unani: Dammul-Akhwain.

Family: Araceae.

Habitat: Maharashtra and Karnata- ka; cultivated in the South.

Siddha/Tamil: Kattu Karunayikki- langu.

Folk: Jangali Suuran.

Action: Root—antidiarrhoeal, anti-inflammatory (prescribed for haemorrhoids), antispasmodic (used in asthma), emmenagogue, abortifacient.... dracontium polyphyllum

Health Promotion Evaluation

An assessment of the extent to which health promotion actions achieve a “valued” outcome.... health promotion evaluation

Health Promotion Outcome

Assessment of changes to personal characteristics and skills, and/or social norms and actions, and/or organizational practices and public policies which are attributable to a health promotion activity.... health promotion outcome

Health-promoting Hospital

A hospital which, not only provides high quality comprehensive medical and nursing services, but also develops a corporate identity that embraces the aims of health promotion; develops a health-promoting organizational structure and culture, including active, participatory roles for patients and all members of staff; develops itself into a health-promoting physical environment; and actively cooperates with its community.... health-promoting hospital

Healthy Public Policy

Public policy characterized by an explicit concern for health and equity in all areas of policy and by an accountability for health impact.... healthy public policy

Discover Saw Palmetto Tea!

If you’re a fan of herbal teas, you have to try saw palmetto tea! It’s special, as it is made from the berries of a small palm. Read more about its health benefits and side effects! About Saw Palmetto Tea Saw palmetto tea is made from the fruit saw palmetto, also known by its scientific name, Serenoa repens. It is the sole species which remains classified in the genus Serenoa. It is a small palm, native to the southeastern part of the United States. Its height varies between 2 and 4m. Its leaves are 1-2m long and have a bare petiole, with a rounded fan of about 20 leaflets at the end; the petiole has fine, sharp teeth or spines. The flowers are small, yellowish-white and produced in dense panicles, and the fruit is a large, reddish-black berry. How to prepare Saw Palmetto Tea A cup of saw palmetto tea can be prepared with either the plant’s berries, or normal teabags. In case you’re using saw palmetto berries, add a teaspoon of the fruits to a cup of freshly boiled water. Let it steep for about 5 minutes, before you strain to remove the berries. Sweeten it, if necessary, with honey or fruit juice. If you’ve got saw palmetto tea bags, follow the instructions on the tea box. Saw Palmetto Tea Constituents Saw palmetto tea gets many active constituents from its main ingredient: saw palmetto berries. The constituents of the berries include a high concentration of fatty acids and phytosterols, as well as beta-sitosterol, capric acid, ferulic acid, palmitic acid, and stearic acid. Saw Palmetto Tea Benefits Saw palmetto tea is known for its important role in treating urinary tract infections. Drinking this tea helps to gently stimulate urination; thanks to this, the infectious microorganisms are “flushed out” along with the urine. Drinking saw palmetto tea helps remove toxins and waste products which can affect and reduce the functions of the kidneys, liver, and bladder. It also helps with the digestive system; it is drunk to treat diarrhea, acid reflux, gas, bloating, and irritable bowel syndrome. Saw palmetto tea also helps calm coughs and treats various forms of chest congestion. It is useful if you’ve got a headache. It can be used to treat benign prostate enlargement and prostatitis, as well. Saw Palmetto Tea Side Effects You shouldn’t drink saw palmetto tea if you’re pregnant or breastfeeding. It can act like a hormone, which might lead to problems. Drinking saw palmetto tea before a surgery is also bad. It might slow down the blood clotting process, which might lead to extra bleeding both during and after the surgery. It is recommended that you stop drinking this tea two weeks before you’ve got a surgery scheduled. Although rare, the possibility of getting an allergic reaction to saw palmetto tea still exists. Symptoms include rashes, itchiness, difficulty in breathing, and swelling of the mouth, tongue or nose. Also, be careful with the amount of saw palmetto tea you drink. The recommended amount is 3-4 cups a day. If you drink too much, you might get some of the following symptoms: dizziness, headache, nausea, vomiting, constipation, and diarrhea. Saw palmetto tea can easily be used as a daily hot beverage. You’re bound to enjoy both the taste and its many health benefits.... discover saw palmetto tea!

Drink More Psyllium Tea

You’ll definitely enjoy a cup of psyllium tea! It is a fiber-full drink which will bring you many health benefits. Find out more about psyllium tea. About Psyllium Tea Psyllium tea is made from the seeds of the psyllium plant. The plant, also known as Isphangula, grows in many European countries, as well as in India. Psyllium is an herbal plant with a short stem. Its leaves are arranged alternatively, while the flowers are white, erect and ovoid; they can also have cylindrical spikes, giving them a stranger shape. The plant has an ovate fruit, with a thin husk, either white-colored or semi-transparent; the seeds, used to make psylliumtea, are found inside it. How to prepare Psyllium Tea The seeds are mostly used to prepare psyllium tea, but the husks can be used, as well. Add 1-2 teaspoons to a cup of freshly boiled water, cover and let it steep for 5-7 minutes. Strain to remove the herbs and your cup of tea is ready! You can also drink it cold. You can either let the psyllium tea cool down, or you can add the seeds and husks to a glass of cold water. Psyllium Tea Benefits Psyllium tea gets many active constituents from the seeds and husks of the plant. The most important one is fiber. It also contains a large amount of hemicellulose. Psyllium tea works as a great natural laxative. Because of this, it can be used in the treatment for irritable bowel syndrome, inflammatory bowel syndrome, and other similar health problems. They also help your digestive system by preventing disorders such as chronic constipation, mild diarrhea, or hemorrhoids. Drinking this tea will help reduce the bad LDL cholesterol levels in your blood, which helps you lose weight. This reduces the risks of having cardiovascular problems, for example heart diseases or strokes. It also lowers blood sugar levels and insulin levels, which helps you if you’ve got diabetes. Other health benefits include preventing colon cancer, as well treating urethritis, hypertension, high blood pressure, and minor infections (intestinal infections, or those of the urinary system). Psyllium Tea Side Effects You might get an allergic reaction after drinking psyllium tea. Symptoms include difficulty in breathing, as well as swelling of lips, tongue and mouth. Make sure you stop drinking psyllium tea and contact your doctor if you get any of these symptoms. If you drink too much tea, you might feel nauseous, or as if you’ve got a bloating stomach. An overdose can lead to obstruction in the colon and severe constipation. Also, in the case of people who have diabetes, if too much is drunk before, after or during a meal, it can cause hypoglycemia. Psyllium tea, just like many other herbal teas, has plenty of important health benefits. It helps you stay healthy, especially thanks to the large contents of fibers. Just be careful with the few side effects.... drink more psyllium tea

Heart Palpitations

Abnormally rapid and irregular beating of the heart... heart palpitations

Drink More Plantain Tea

If you haven’t heard much about plantain tea, it’s time to find out! As an herbal tea, it has a pretty pleasant, earthy taste, as well as many health benefits. About Plantain Tea Plantain tea is made from plantain. It is a perennial plant that grows all around the world, in Europe, Asia, Africa and America. The plantain has a tough rhizome with several large, dark green leaves. The flowers of the plant are brown, with four stamens and purple-colored anthers and the fruit is a two-celled capsule with seeds inside it. Many consider this plant to be a weed. However, the leaves are edible, and are often used in salads, or cooked as greens. Plantain Tea constituents Plantain, as an herbal plant, has many important active constituents. They include beta carotene, calcium, linoleic acid, oleanolic acid, sorbitol, tannin, and vitamin C. They are all transferred to plantain tea, as well. How to prepare Plantain Tea For a cup of plantain tea, you can use the leaves, roots and/or seeds of the plant. Just add one tablespoon of the dried plants to a cup of freshly boiled water. Let it steep for about 10 minutes, then strain. You can drink it both hot and cold. Plantain Tea Benefits Plantain tea is often used in the treatment of various respiratory problems, as it acts as a mild expectorant. These include asthma, bronchitis, sinusitis, sore throats, and coughs. Plantain tea can also be used to lower blood pressure and control sugar blood levels. Drinking plantain tea can help you if you’ve got diarrhea or dysentery. It is also used to treat irritated or bleeding hemorrhoids, kidney and bladder problems, bleeding caused by cystitis, and urinary tract infections. Plantain tea can be used topically, as well. It works as an antivenin, and it also promotes the healing of various wounds, skin inflammations, scars, cuts, rashes, and swellings. It can also be applied to the eye, in case your eyes are irritated. Plantain Tea Side Effects If you’re pregnant, it’s best to avoid drinking plantain tea. It can affect the uterus, which might lead to unwanted miscarriages. It is not known how safe it is to drink plantain tea if you’re breast feeding, but it is recommended to avoid it, just in case it might affect the baby. Don’t drink plantain tea if you’re allergic to any plants part of the plantain family. Also, you might get an allergic reaction from drinking the tea if you’re allergic to melon. Drinking too much plantain tea may lead to some side effects, as well. Generally, it is recommended that you not drink more than 5-6 cups of tea, no matter the type of tea. If you’re drinking too much tea, you might get some of the following symptoms: diarrhea, low blood pressure, headaches, loss of appetite, vomiting, insomnia, dizziness, and irregular heartbeats. Plantain tea helps you stay healthy! It is considered safe for both children and adults. Just be careful with the few side effects and you’re free to enjoy plantain tea!... drink more plantain tea

Drosera Peltata

Sm.

Synonym: D. lunata Buch.-Ham.

Family: Droseraceae.

Habitat: Throughout India, up to 2,438 m.

Ayurvedic: Brahma-suvarchalaa (doubtful synonym).

Folk: Mukhjali. (Drosera burmannii Vahl is also known as Mukhjali.)

Action: Resin from plant—used in bronchitis and whooping cough. Plant—antisyphyilitic. Bruised leaves, mixed with salt are applied for treating blisters.

Key application: Drosera rotundifo- lia—in dry cough and coughing fits, as bronchoantispasmodic. (German Commission E.).

The leaves contain napthaquinones, plumbagin (0.5%), droserone (3-hy- droxyplumbagin) and hydroxydro- serone (0.01%), and the flavonoids, quercetin, gossypetin, gossypin and isogossypitrin. The antispasmodic action of the herb has been attributed to naphthoquinones. Plumbagin is antimicrobial in vitro against some Gram-positive and Gram-negativebac- teria, influenza virus, pathogenic fungi and parasitic protozoa, and is active against some species of Leishmania. In large doses plumbagin is cytotoxic, but in small doses exhibits immunostimu- lating activity in vitro.

A related species, Drosera indica Linn., is found in Deccan peninsula, particularly in the West coast. Plum- bagone, isolated from the plant, depresses the isolated intestine of the guinea-pig and suppresses the effect of acetylcholine. In Indo-China, a maceration of the plant is applied topically to corns.

In Western herbal, Sundew is obtained from the aerial parts of Drosera rotundifolia which grows throughout Europe.... drosera peltata

Henoch-schönlein Purpura

This is an in?ammatory condition of the small blood vessels, the cause of which is not known but may be an allergic response to food or drugs. Most common among young children, the in?ammation causes blood to leak into joints, kidneys, intestine and skin. The child presents with a purpuric rash and stomach pains which may come and go for weeks. Paracetamol alone is often su?cient to alleviate the condition, but severely ill patients may need corticosteroid drugs. All sufferers need follow-up for 12 months to ensure that they have not developed kidney disease.... henoch-schönlein purpura

Home And Community-based Services; Home And Community Care Programme

See “community-based care”.... home and community-based services; home and community care programme

Idiopathic Facial Nerve Palsy

See BELL’S PALSY.... idiopathic facial nerve palsy

Immune Person/animal

A person or animal that possesses specific previous antibodies or cellular immunity as a result of previous infection or immunisation, or is so conditioned by such previous specific experience as to respond adequately with production of antibodies sufficient to prevent illness following exposure to the specific infectious agent of the disease. Immunity is relative; an ordinarily effective protection may be overwhelmed by an excessive dose of the infectious agent or an unusual portal of entry.... immune person/animal

Drinking Tea For Pregnancy

Women need to be careful both with what they eat and drink during pregnancy. Even if tea is generally recommended as an everyday beverage, most teas shouldn’t be drunk during pregnancy. Find out which teas you should and shouldn’t drink when you’re pregnant. Careful with teas for pregnancy There are various reasons why pregnant women should be careful with the type of tea they drink. Many are related to the caffeine content some tea varieties might have. Drinking tea with caffeine content might lead to birth defects or even unwanted miscarriages. Also, other tea varieties can lead to uterine contractions, or have properties that involve regulating menstruation. These can also lead to miscarriages. That doesn’t mean that, during pregnancy, women should completely stay away from teas. They just have to know what type of tea they can drink. Teas you can drink for pregnancy Rooibos tea is often recommended to pregnant women, as it doesn’t contain caffeine at all. It contains antioxidants, as well as a low level of tannins. Thanks to this, they are less likely to interfere with iron absorption and, therefore, cause anemia during and after pregnancy. It also helps with indigestion and may relieve nausea. Pregnant women can drink ginger tea or mint tea, which help with morning sickness, or chamomile tea to prevent insomnia. Also, nettle tea can be drunk during the second and third trimester of the pregnancy (not the first) only if it’s made from nettle leaves and not from the root. Raspberry leaf tea has many benefits related to pregnancy. First of all, if a woman wants to get pregnant, this tea will increase fertility, as well as strengthen the uterine wall and relax the muscle in the uterus. During pregnancy, it helps with leg cramps, morning sickness and diarrhea. Also, drinking this tea may lead to less artificial ruptures in the membranes, which lowers the chances of needing a caesarean delivery, as well as needing forceps or vacuum birth. Teas you shouldn’t drink for pregnancy Even if teas are usually considered to be good for our health, this isn’t the case. Women should be careful not to drink various types of tea for pregnancy. It is considered best for pregnant women not to drink teas that contain caffeine. Teas made from the Camellia sinensis plant (green tea, black tea, white tea, oolong tea) contain caffeine, so it is best to avoid them. Small amounts may be acceptable, however it can still be risky, as they might still lead to birth defects or miscarriages. Pregnant women should also be careful with herbal teas. The varieties they shouldn’t drink include devil’s claw, ephedra, fenugreek, gentian, ginseng, hawthorne, motherwort, red raspberry leaf, senna, shepherd’s purse, St. John’s wort, or yarrow. Teas for labor Partridge tea is recommended for pregnant women who are due to give birth. It is recommended to be drunk during the last 2-3 weeks of pregnancy. Partridge tea helps with relieving congestions of the uterus and ovaries. It can also be used as an antiseptic to treat vaginal infections. Plus, when it is combined with raspberry leaves, it can help even more during the last two weeks of pregnancy. Pregnant women should be careful even when it comes to the type of tea they drink. Some might be harmful, while others may help them a lot both during and after pregnancy. If you want to get pregnant, make sure you remember the accepted teas for pregnancy.... drinking tea for pregnancy

Drugs In Pregnancy

Unnecessary drugs during pregnancy should be avoided because of the adverse e?ect of some drugs on the fetus which have no harmful e?ect on the mother. Drugs may pass through the PLACENTA and damage the fetus because their pharmacological effects are enhanced as the enzyme systems responsible for their degradation are undeveloped in the fetus. Thus, if the drug can pass through the placenta, the pharmacological e?ect on the fetus may be great whilst that on the mother is minimal. WARFARIN may thus induce fetal and placental haemorrhage and the administration of THIAZIDES may produce THROMBOCYTOPENIA in the newborn. Many progestogens have androgenic side-effects and their administration to a mother for the purpose of preventing recurrent abortion may produce VIRILISATION of the female fetus. Tetracycline administered during the last trimester commonly stains the deciduous teeth of the child yellow.

The other dangers of administering drugs in pregnancy are the teratogenic effects (see TERATOGENESIS). It is understandable that a drug may interfere with a mechanism essential for growth and result in arrested or distorted development of the fetus and yet cause no disturbance in the adult, in whom these di?erentiation and organisation processes have ceased to be relevant. Thus the e?ect of a drug upon a fetus may di?er qualitatively as well as quantitatively from its e?ect on the mother. The susceptibility of the embryo will depend on the stage of development it has reached when the drug is given. The stage of early di?erentiation – that is, from the beginning of the third week to the end of the tenth week of pregnancy – is the time of greatest susceptibility. After this time the risk of congenital malformation from drug treatment is less, although the death of the fetus can occur at any time.... drugs in pregnancy

Indemnity Plan

Provides reimbursement to the insured without regard to the expenses actually incurred.... indemnity plan

Indian Medicinal Plants

Indian Medicinal Plants

[catlist id=3 numberposts=100 pagination=yes instance=2 orderby=title order=asc]

... indian medicinal plants

Indian Paint Brush

Love... indian paint brush

Indian Potato Or Eskimo Potato

Claytonia species

Description: All Claytonia species are somewhat fleshy plants only a few centimeters tall, with showy flowers about 2.5 centimeters across.

Habitat and Distribution: Some species are found in rich forests where they are conspicuous before the leaves develop. Western species are found throughout most of the northern United States and in Canada.

Edible Parts: The tubers are edible but you should boil them before eating.... indian potato or eskimo potato

Individual Programme Plan

See “care plan”.... individual programme plan

Endotracheal Catheters Are Used To Pass

down the TRACHEA into the lungs, usually in the course of administering anaesthetics (see under ANAESTHESIA).

Eustachian catheters are small catheters that are passed along the ?oor of the nose into the Eustachian tube in order to in?ate the ear.

Nasal catheters are tubes passed through the nose into the stomach to feed a patient who cannot swallow – so-called nasal feeding.

Rectal catheters are passed into the RECTUM in order to introduce ?uid into the rectum.

Suprapubic catheters are passed into the bladder through an incision in the lower abdominal wall just above the pubis, either to allow urine to drain away from the bladder, or to wash out an infected bladder.

Ureteric catheters are small catheters that are passed up the ureter into the pelvis of the kidney, usually to determine the state of the kidney, either by obtaining a sample of urine direct from the kidney or to inject a radio-opaque substance preliminary to X-raying the kidney. (See PYELOGRAPHY.)

Urethral catheters are catheters that are passed along the urethra into the bladder, either to draw o? urine or to wash out the bladder.

It is these last three types of catheters that are most extensively used.... endotracheal catheters are used to pass

Enjoy Prickly Ash Tea

If you feel like drinking an herbal tea with plenty of health benefits, you should try prickly ash tea. Even if the taste is bitter, the tea is bound to help you stay healthy. Find out more about it in this article! About Prickly Ash Tea Prickly ash tea is made from the bark of the prickly ash. The plant is also known as Devil’s Walkingstick, Hercules’s Club or Prickly Elder. The plant grows in the eastern parts of North America. Prickly ash is a tall shrub, usually reaching 6m in height. It has a stem with large leaves, 70-120cm long. The flowers bloom in late summer; they’re small and creamy-white. Also, the fruits are a small, purple-black berry. How to make Prickly Ash Tea It’s easy to make prickly ash tea. Boil the necessary amount of water and add a teaspoon of chopped bark for each cup of tea. Let it steep for 5-7 minutes; then, strain in order to remove the herbs. If it tastes too bitter for you, you can sweeten the tea with milk, honey or fruit juices. Prickly Ash Tea Benefits Prickly ash tea gets important active constituents from the bark of its plant. These include chelerythin alkaloids, tannins, lignans, resins, and volatile oils. You can drink prickly ash tea if you’ve got toothaches, abdominal pains (or any other chronic pains) or diarrhea. It is also used in killing intestinal parasites, and treating arthritis and rheumatism. It is also useful in treating circulation problems and lowering blood pressure. You can drink it if you’ve got a cold or a sore throat. Prickly ash tea can also be combined with other ingredients, for different health benefits. Combined with ginger, it alleviates chronic abdominal pains, and treats nausea and vomiting caused by long-term illnesses. It can also be combined with coptis or Oregon grape root in order to treat symptoms caused by roundworms. Prickly Ash Tea side Effects It is best not to drink prickly ash tea if you’re pregnant or breast feeding. It’s not quite sure how it can affect the baby, but it might, so it’s better to stop drinking it during these periods. Be careful with the amount of tea you drink if you’ve got low blood pressure. Prickly ash tea helps lower the blood pressure, so it might end up causing some harm (hypotension). Also, if you drink this tea while taking medication (aspirin, warfarin, heparin, tinzaparin), the combination might lead to bleeding and bruising. Also, don’t drink prickly ash tea if you’ve got stomach or intestinal problems: ulcerative colitis, peptic ulcer disease, gastroesophageal reflux, Crohn’s disease, irritable bowel syndrome, infections, and other digestive tract conditions. It’s bound to make your stomach and intestinal problems worse. Also, dopn’t drink this tea if you’ve got a fever with profuse sweating. Despite its bitter taste, you should give prickly ash tea a chance, especially thanks to its health benefits. As an herbal tea, it’s bound to keep you healthy!... enjoy prickly ash tea

Infantile Paralysis

An old name for POLIOMYELITIS.... infantile paralysis

Infected Person

A person who harbours an infectious agent and who has either manifest disease or inapparent infection. An infectious person is one from whom the infectious agent can be naturally acquired.... infected person

International Classification Of Health Problems In Primary Care (ichppc)

A classification of diseases, conditions and other reasons for attendance for primary care. This classification is an adaptation of the ICD but makes allowance for the diagnostic uncertainty that prevails in primary care.... international classification of health problems in primary care (ichppc)

International Classification Of Primary Care (icpc)

The official classification of the World Organisation of Family Doctors. It includes three elements of the doctor-patient encounter: the reason for the encounter; the diagnosis; and the treatment or other action or intervention.... international classification of primary care (icpc)

International Statistical Classification Of Diseases And Related Health Problems, Tenth Revision (icd-10)

A list of diagnoses and identifying codes used by medical practitioners and other health care providers. The coding and terminology provide a uniform language that permits consistent communication on claim forms. Data from earlier time periods were coded using the appropriate revision of the ICD for that time period. Changes in classification of causes of death in successive revisions of the ICD may introduce discontinuities in cause of death statistics over time.... international statistical classification of diseases and related health problems, tenth revision (icd-10)

Enjoy A Cup Of Rose Petal Tea

It you want to drink a special type of herbal tea, try the rose petal tea. It is aromatic, with a pleasant taste, and you’re bound to enjoy it. It also has important health benefits. Find out more about rose petal tea! About Rose Petal Tea Rose petal tea is made from the petals of a flower most adored by many women: the rose. This woody perennial plant has over 100 species which grow in Asia, Europe, North America, and northwest Africa. Roses grow as a group of erect shrubs, acting like climbing plants. Its stems often have small, sharp thorns. The leaves are oval-shaped with sharply-toothed edges, and they’re about 10cm long. The fruit is called rosehip; it is ripe from late summer to autumn, and it is edible. The flowers usually have 5 petals with two distinct lobes; they are usually pink, white, red, or yellow. You can make tea both from the rose petals and from the rose’s fruit, the rosehip. How to prepare Rose Petal Tea When making rose petal tea, first make sure that the petals you use are free of pesticides. Roses from gardens and flower shops are usually treated with pesticides, and shouldn’t be used to make rose petal tea. To enjoy rose petal tea, add about two handfuls of properly washed and dry rose petals to a pot with water for three cups of tea. Leave the pot over medium heat for 5 minutes, or until the petals have lost their original color, becoming darker. Stream to remove the petals and sweeten, if necessary, with honey or fruit juice. Rose Petal Tea Components Rose petal tea gets many active components from the rose petals: cyclic monoterpene alcohols, geraniol, citronellol and nerol are just a few important ones. It also includes long-chain hydrocarbons (nonadecane, heneicosane). These active components lead to the many health benefits rose petal tea has. Rose Petal Tea Benefits Rose petal tea helps strengthen your immunity, and can be part of the treatment for colds. It is useful if you’ve got a fever, a runny nose, a sore throat, or bronchial congestion. Also, it helps clean your body of toxins. Drinking rose petal tea can help during menstrual periods, if you’ve got a heavy menstrual flow. It can also reduce menstrual cramps, and helps regulate your period. Rose petal tea is often used to treat diarrhea and dysentery. It can also help you fight against depression, fatigue and insomnia. Rose petal tea also acts as a digestive aid, as it protects the gastrointestinal tract. It is often used to treat constipation, gastroenteritis, diarrhea, and dysentery; the tea also nourishes the gastric mucosa. You can drink rose petal tea to treat urinary tract infections, as well. Rose Petal Tea Side Effects No important side effects of rose petal tea have been noted. Still, it is considered best not to drink more than 5 cups of tea a day. If you drink too much, you might get some of these symptoms: headaches, loss of appetite, vomiting, diarrhea, insomnia, dizziness, and irregular heartbeats. Spoil yourself with a delicious cup of rose petal tea! Not only will you enjoy its taste, but its health benefits, as well.... enjoy a cup of rose petal tea

Exogonium Purga

Benth.

Synonym: Ipomoea purga Hayne.

Family: Convolvulaceae.

Habitat: Native to Amercia. Grows in Southern and Eastern India.

English: Jalap.

Unani: Jalaapaa.

Action: Tuber—drastic hydr- agogue cathartic, acts briskly, causes watery evacuations. Overdoses produce hypercatharsis. Contraindicated in inflammatory conditions of the bowels. (The roots of Operculina turpethum synonym Ipomoea turpethum are used as a substitute for jalap.)... exogonium purga

Ferula Persica

Willd.

Family: Umbeliferae; Apiaceae.

Habitat: Native to Arabia and Persia.

English: Sagapenum.

Unani: Sakbeenaj, Sakbekh.

Family: Umbelliferae; Apiaceae.

Habitat: Native to Central Asia.

English: Musk Root.

Folk: Sumbul, Sambala.

Action: Used as a sedative in hysteria and other nervous disorders. Also used as a mild gastrointestinal stimulant. Formerly used for asthma, bronchitis and amenorrhoea.

Ferula sumbul contains 0.2-0.4% volatile oil; 5-15% resin; hydroxy- coumarins including umbelliferone; sumbulic and angelic acids.... ferula persica

Intravenous Pyelogram (urogram)

A procedure for getting X-ray pictures of the URINARY TRACT. A radio-opaque medium is injected into a vein and, when it is excreted by the kidneys, the substance can be identi?ed on X-rays. Any abnormalities in structure or foreign bodies such as calculi are outlined by the dye (see KIDNEYS, DISEASES OF).... intravenous pyelogram (urogram)

Iris Pseudacorus

Linn.

Family: Iridaceae.

Habitat: On river banks, by the side of lakes, ponds. Native to Great Britain.

English: Yellow Flag.

Folk: Paashaanabheda (Gujarat).

Action: Cathartic and acrid. Used in dysmenorrhoea and leucorrhoea. Juice of the root—used for obstinate coughs and convulsions.

Rhizomes contain a glycoside, irisin, iridin or irisine, reportedly present, with myristic acid.... iris pseudacorus

Justicia Procumbens

Linn.

Family: Acanthaceae.

Habitat: Western Ghats, West Coast from Konkan to Kerala; abundant in the rainy season.

Ayurvedic: Parpata (substitute).

Action: The plant contains naphthofuranones, justicidin A, B, C, D, G and H, and diphyllin, which are used for the treatment of osteoporosis. The flowers contain peonidine glucoside. Essential oil— antifungal.... justicia procumbens

Enjoy Periwinkle Tea

If you like herbal teas, there are lots of types you can try - one of them is periwinkle tea. Like most herbal teas, it has a slightly bitter taste, but it also has important health benefits. Read to find out more about periwinkle tea! About Periwinkle Tea Periwinkle tea is made from the vinca plant, an herbaceous plant which can be found in Europe, northwest Africa and southwest Asia. Vinca plant has long, trailing stems that grow near the ground, touching it. The branches can reach about half a meter in height. The leaves are evergreen and, opposite, the flowers are salverform, with 5 vilet (and sometimes white) petals connected together at the base. Two species of the plant are often cultivated as ornamental plants. However, in some parts of Australia, New Zealand, and the United States, it has spread too much, becoming an invasive plant. Interestingly, it is said that the plant protects you from voodoo magic. Periwinkle Tea constituents Vinca plants have lots of constituents which are transferred to periwinkle tea, as well. Periwinkle tea is rich in alkaloids that come from the vinca plant. It has at least 86 different alkaloids. Some of them are: vincamine, vinpocetine, vinblastine, vincristine, alstonine, ajmalicine, leurocristine, and reserpine. How to prepare Periwinkle Tea For a cup of periwinkle tea, you need a teaspoon of dried herbs. Pour boiling water into the cup and let it steep for 10-15 minutes. Once the steeping time is done, strain to remove the herbs and your cup of periwinkle tea is done. If the taste is too bitter for you, you can sweeten the tea by adding honey or fruit juice to your cup. Periwinkle Tea Benefits Thanks to the many constituents derived from the vinca plant, periwinkle tea has lots of important health benefits. Periwinkle tea plays an important role in the fight against cancer. It is often recommended in the treatment for leukemia, Hodgkin’s disease, malignant lymphomas, neuroblastoma, Wilm’s tumor and Kaposi’s sarcoma. Drinking periwinkle tea will help lower blood sugar levels and blood pressure, as well as improve blood circulation. You can drink periwinkle tea during menstruation if you’ve got an excessive blood flow. It should help in such situations. This tea is also useful in treating diarrhea, colitis and diabetes. You can use periwinkle tea to treat mouth sores and bleeding gums; it acts as a good mouth rinse. It can help you with headaches and memory loss problems and it enhances your memory. It also has calming effects, helping you with anxiety and nervousness. Periwinkle tea can be used topically, as well. You can wet a cloth with tea and use it to stop wounds from bleeding. You can also put it on the skin to treat wasp stings or on the eye if you’ve got an eye infection. Periwinkle Tea Side Effects With so many health benefits, periwinkle tea has to have a few side effects too. Here are some which you have to be careful with. If you’ve got kidney, liver or lung diseases, you should avoid drinking periwinkle tea. Also you should not drink it if you’ve got low blood pressure, or if you’re constipated. Pregnant women shouldn’t drinkperiwinkle tea, as it may lead to birth defects or even miscarriages. Also, it is best to stay away from this tea if you’re breast feeding; even in this case, it might affect the baby. It is best to stop drinking periwinkle tea before a surgery. It can lower blood pressure and it might lead to problems during and after the surgery. Check with your doctor and make sure you’re safe to drink periwinkle tea after a surgery. It is also recommended that you not drink more than 4 cups of periwinkle tea. Besides the usual symptoms (low blood pressure and constipation) you might also get other symptoms: headaches, loss of appetite, insomnia, dizziness, and irregular heartbeats. Drinking periwinkle tea can help you a lot, with its many health benefits. Don’t forget about the side effects, though. As long as you make sure it’s safe to drink periwinkle tea, you can happily drink it!... enjoy periwinkle tea

Ficus Palmata

Forsk.

Synonym: F. caricoides Roxb. F. virgata Wall. ex Roxb.

Habitat: North-western India and Rajasthan, from Kashmir eastward to Nepal, ascending to 1,000 m.

English: Indian Fig.

Ayurvedic: Phalgu, Anjiri.

Siddha: Manjimedi (Telugu).

Action: Fruit—demulcent and laxative. Latex is applied on pimples. Ripe fruits—hypotensive.

Leaves gave bergapten and beta- sitosterol.... ficus palmata

Klumpke’s Paralysis

Injury as a result of the stretching of a baby’s brachial plexus during its birth may cause partial paralysis of the arm with atrophy of the muscles of the forearm and hand.... klumpke’s paralysis

Lassar’s Paste

O?cially known as Zinc and Salicylic Acid Paste, BP, this preparation is an old remedy for eczema (see DERMATITIS).... lassar’s paste

Launaea Pinnatifida

Cass.

Synonym: L. sarmentosa (Willd.) Alston.

Family: Compositae; Asteraceae.

Habitat: Sandy coasts of India.

Ayurvedic: Gojihvaa, Golomikaa. (Gaozabaan, used in Unani medicine, is equated with Bor- aginaceae sp.)

Folk: Vana-gobhi; Paathri (Maharashtra).

Action: Plant—galactagogue, soporific, diuretic, aperient.... launaea pinnatifida

Lilium Polyphyllum

D. Don.

Family: Liliaceae.

Habitat: Uttaranchal, Himachal Pradesh.

Ayurvedic: Kaakoli, Madhuraa, Kshira, Vayhasthaa, Karnikaa, Vaayasoli.

Action: Tuberous root—used as a tonic in emaciation and as a source of energy, after dry roasting.

Dosage: Tuberous root—3-6 g. (API, Vol. III.)... lilium polyphyllum

Fishtail Palm

Caryota urens

Description: Fishtail palms are large trees, at least 18 meters tall. Their leaves are unlike those of any other palm; the leaflets are irregular and toothed on the upper margins. All other palms have either fan-shaped or featherlike leaves. Its massive flowering shoot is borne at the top of the tree and hangs downward.

Habitat and Distribution: The fishtail palm is native to the tropics of India, Assam, and Burma. Several related species also exist in Southeast Asia and the Philippines. These palms are found in open hill country and jungle areas.

Edible Parts: The chief food in this palm is the starch stored in large quantities in its trunk. The juice from the fishtail palm is very nourishing and you have to drink it shortly after getting it from the palm flower shoot. Boil the juice down to get a rich sugar syrup. Use the same method as for the sugar palm to get the juice. The palm cabbage may be eaten raw or cooked.... fishtail palm

Lydia Pinkham

Manufactured herbal preparation sold at botánicas and used for women’s health conditions, including menopause, infertility, vaginal infections, menstrual irregularities and uterine fibroids.... lydia pinkham

Lysol Poisoning

When LYSOL is swallowed it burns the mouth and throat. Brown discoloration of the affected tissues, accompanied by the characteristic smell of lysol on the breath, is typical.

Treatment This is urgent. If the skin has been contaminated with the lysol, it must be washed with water, and any lysol-contaminated clothing must be taken o?. Do not make the victim vomit if he or she has swallowed a corrosive substance such as lysol or phenol. Call an ambulance and say what the victim has taken. See APPENDIX 1: BASIC FIRST AID.... lysol poisoning

Lytocarpus Philippinus

Commonly known as fireweed, Lytocarpus is a stinging hydroid (hydrozoan) that grows on pilings, rocks and overhangs in tropical and sub-tropical areas of the world. Skin contact causes an itchy vesicular rash.... lytocarpus philippinus

Malaria Prophylaxis

Measures taken for protection against malaria, e.g. administration of a drug and personal protective measures that prevent a person from becoming infected with the disease.... malaria prophylaxis

Fumaria Parviflora

Lam.

Synonym: F. indica (Haussk.) Pugsley.

Family: Fumariaceae.

Habitat: At high altitudes in Tamil Nadu; up to 2,700 m on the Himalayas.

English: Fumitory.

Ayurvedic: Parpata, Parpata- ka, Varatikta, Renu, Kavacha, Sukshmapatra.

Unani: Shaahtaraa.

Siddha/Tamil: Thura.

Folk: Pittapaaparaa.

Action: Detoxifying, laxative, diuretic, diaphoretic.

The plant contains isoquinoline alkaloids-including protopine, sangui- narine, cryptopine, d-bicuculline, fu- maridine, fumaramine. The leaves contain kaempferol and quercetin glycosides.

Dosage: Whole plant-1-3 g (API Vol. IV); 3-35 g powder; 50-100 ml decoction. (CCRAS.)... fumaria parviflora

Garcinia Pedunculata

Roxb.

Family: Guttiferae; Clusiaceae.

Habitat: Forests of northeast Bengal, sporadic in NEFA, Manipur and upper Assam

Ayurvedic: Amlavetasa. Vetasaamla.

Folk: Thaikala (Bengal).

Action: Antiscorbutic, astringent, cooling, cardiotonic, emollient. Used in anorexia, dyspepsia, colic, liver and spleen diseases difficult micturition. Cough and other respiratory disorders, ulcers and skin diseases.

Dry fruits (pericarp) contain the benzophenones, pedunculol, garcinol and cambogin.

The heartwood gave benzophenone and xanthone.

Dosage: Fruit—5-10 ml juice. (CCRAS.)... garcinia pedunculata

Garuga Pinnata

Roxb.

Family: Burseraceae.

Habitat: Throughout India, up to 1,000 m on the hills.

English: Grey Downy Balsam.

Ayurvedic: Paaranki, Kharpata. (Kinkiraata, Karnikaara, Mri- galindika are doubtful synonyms.)

Siddha/Tamil: Karre Vembu, Arunelli.

Folk: Ghogar, Toon.

Action: Fruit—stomachic. Leaf— astringent, antiasthmatic. Bark— antidiabetic.

The leaves and stem bark contain sterols, sitosterol, stigmasterol and campesterol; fatty acids; aliphatic compounds; a mixture of long chain esters; along with tannins and waxes. The leaves also contain garu- garin and amentoflavone. Gum-resin contains alpha-amyrin, butyrospermol and dammarandiol.

Aqueous and ethanolic extract of the leaves exhibit anti-inflammatory and antiallergic activities.... garuga pinnata

Malpighia Punicifolia

Linn.

Family: Malpighiaceae.

Habitat: Cultivated in Tamil Nadu and Karnataka.

English: West Indian Cherry.

Folk: Vallari (Telugu), Simeyaranelli (Kannada).

Action: See Malpighia glabra.

Fruits contain ascorbic acid in high concentration (green fruits contain up to 3,000 mg/100 g). 3-methyl-3- buten-1-ol has been identified as major volatile constituent of the fruit.... malpighia punicifolia

Managed Care Plan

A health plan that uses managed care arrangements and has a defined system of selected providers who contract with the plan. Those enrolled have a financial incentive to use participating providers who agree to furnish a broad range of services to them. Providers may be paid on a pre-negotiated basis.... managed care plan

General Practitioner (gp)

A general practitioner (‘family doctor’; ‘family practitioner’) is a doctor working in primary care, acting as the ?rst port of professional contact for most patients in the NHS. There are approximately 35,000 GPs in the UK and their services are accessed by registering with a GP practice – usually called a surgery or health centre. Patients should be able to see a GP within 48 hours, and practices have systems to try to ensure that urgent problems are dealt with immediately. GPs generally have few diagnostic or treatment facilities themselves, but can use local hospital diagnostic services (X-rays, blood analysis, etc.) and can refer or admit their patients to hospital, where they come under the supervision of a CONSULTANT. GPs can prescribe nearly all available medicines directly to their patients, so that they treat 90 per cent of illnesses without involving specialist or hospital services.

Most GPs work in groups of self-employed individuals, who contract their services to the local Primary Care Trust (PCT) – see below. Those in full partnership are called principals, but an increasing number now work as non-principals – that is, they are employees rather than partners in a practice. Alternatively, they might be salaried employees of a PCT. The average number of patients looked after by a full-time GP is 1,800 and the average duration of consultation about 10 minutes. GPs need to be able to deal with all common medical conditions and be able to recognise conditions that require specialist help, especially those requiring urgent action.

Until the new General Medical Services Contract was introduced in 2004, GPs had to take individual responsibility for providing ‘all necessary medical services’ at all times to their patient list. Now, practices rather than individuals share this responsibility. Moreover, the contract now applies only to the hours between

8.00 a.m. and 6.30 p.m., Mondays to Fridays; out-of-hours primary care has become the responsibility of PCTs. GPs still have an obligation to visit patients at home on weekdays in case of medical need, but home-visiting as a proportion of GP work has declined steadily since the NHS began. By contrast, the amount of time spent attending to preventive care and organisational issues has steadily increased. The 2004 contract for the ?rst time introduced payment for speci?c indicators of good clinical care in a limited range of conditions.

A telephone advice service, NHS Direct, was launched in 2000 to give an opportunity for patients to ‘consult’ a trained nurse who guides the caller on whether the symptoms indicate that self-care, a visit to a GP or a hospital Accident & Emergency department, or an ambulance callout is required. The aim of this service is to give the patient prompt advice and to reduce misuse of the skills of GPs, ambulance sta? and hospital facilities.

Training of GPs Training for NHS general practice after quali?cation and registration as a doctor requires a minimum of two years’ post-registration work in hospital jobs covering a variety of areas, including PAEDIATRICS, OBSTETRICS, care of the elderly and PSYCHIATRY. This is followed by a year or more working as a ‘registrar’ in general practice. This ?nal year exposes registrars to life as a GP, where they start to look after their own patients, while still closely supervised by a GP who has him- or herself been trained in educational techniques. Successful completion of ‘summative assessment’ – regular assessments during training – quali?es registrars to become GPs in their own right, and many newly quali?ed GPs also sit the membership exam set by the Royal College of General Practitioners (see APPENDIX 8: PROFESSIONAL ORGANISATIONS).

A growing number of GP practices o?er educational attachments to medical students. These attachments provide experience of the range of medical and social problems commonly found in the community, while also o?ering them allocated time to learn clinical skills away from the more specialist environment of the hospital.

In addition to teaching commitments, many GPs are also choosing to spend one or two sessions away from their practices each week, doing other kinds of work. Most will work in, for example, at least one of the following: a hospital specialist clinic; a hospice; occupational medicine (see under OCCUPATIONAL HEALTH, MEDICINE AND DISEASES); family-planning clinics; the police or prison services. Some also become involved in medical administration, representative medicopolitics or journalism. To help them keep up to date with advances and changes in medicine, GPs are required to produce personal-development plans that outline any educational activities they have completed or intend to pursue during the forthcoming year.

NHS GPs are allowed to see private patients, though this activity is not widespread (see PRIVATE HEALTH CARE).

Primary Care Trusts (PCTs) Groups of GPs (whether working alone, or in partnership with others) are now obliged by the NHS to link communally with a number of other GPs in the locality, to form Primary Care Trusts (PCTs). Most have a membership of about 30 GPs, working within a de?ned geographical area, in addition to the community nurses and practice counsellors working in the same area; links are also made to local council social services so that health and social needs are addressed together. Some PCTs also run ambulance services.

One of the roles of PCTs is to develop primary-care services that are appropriate to the needs of the local population, while also occupying a powerful position to in?uence the scope and quality of secondary-care services. They are also designed to ensure equity of resources between di?erent GP surgeries, so that all patients living in the locality have access to a high quality and uniform standard of service.

One way in which this is beginning to happen is through the introduction of more overt CLINICAL GOVERNANCE. PCTs devise and help their member practices to conduct CLINICAL AUDIT programmes and also encourage them to participate in prescribing incentive schemes. In return, practices receive payment for this work, and the funds are used to improve the services they o?er their patients.... general practitioner (gp)

Medicinal Plants

Medicinal Plants

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... medicinal plants

Medicinal Plants Glossary

Medicinal Plants Glossary

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... medicinal plants glossary

Glycosmis Pentaphylla

(Retz.) DC.

Synonym: G. arborea (Roxb.) A. DC.

G. cochinchinensis Gamble. Limonia pentaphylla Retz.

Family: Rutaceae.

Habitat: Peninsular India and Andaman Islands. Cultivated in gardens.

Ayurvedic: Vana-nimbuukaa, Ashwa-shaakhota.

Siddha/Tamil: Konji, Amam, Kula-pannai.

Folk: Bana-Nimbu, Paanal (Kerala).

Action: Plant—bechic, anti- anaemic, antirheumatic. Root— anti-inflammatory. Leaf—used in Jaundice and liver disorders, eczema and other skin affections. Leaf and root—vermifuge, febrifuge. A paste of the wood is applied externally to pimples.

Leaf extract from a Sri Lankan plant yielded the alkaloids arborine, skim- mianine and arborinine. The steam distillate of leaves showed significant antifungal activity.... glycosmis pentaphylla

Grapefruit Peel Tea

Grapefruit Peel Tea is known for many years due to its antibacterial and antifungal properties. As the name suggests, grapefruit peel tea is made from the peel of the grapefruit, the white portion under the rind, which is very rich in antioxidants that help strengthen your immune system. It also contains pectin and fiber, substances that help lower the bad cholesterol levels in the body. How To Make Grapefruit Peel Tea You can make Grapefruit Peel Tea by mincing the white rind of the fruit and placing it in about 8 cups of boiled water. Let the mix boil for about 2 minutes and after that, let it steep for 15 minutes. Keep in mind that grapefruit peel tea has a bitter taste and you might consider sweeten it with honey or sugar. Grapefruit Peel Tea Benefits
  • Helps remove toxins from the body.
  • Clears the respiratory tract.
  • Lowers bad cholesterol.
  • Provides relaxation.
  • Helps fight allergies.
  • Strong allied in the treatment of some digestive and bladder problems.
Grapefruit Peel Tea Side Effects
  • Pregnant or breastfeeding women should avoid drinking Grapefruit Peel Tea.
  • Grapefruit peel tea may interact with the effects of some medications, so make sure you always consult your doctor before drinking grapefruit peel tea.
  • Try not to drink excessive amounts of Grapefruit Peel Tea if you have breast cancer or a higher than usual risk of developing breast cancer.
All in all, Grapefruit Peel Tea can be a healthy start for your day, giving you the energy that you need due to its many vitamins. Just keep in mind its side effects and try to avoid as much as you can experiencing them!... grapefruit peel tea

Graptophyllum Picum

(L.) Griff.

Synonym: G. hortense Nees. Justica picta L.

Family: Acanthaceae.

Habitat: A native to Polynesia; introduced into Indian gardens.

English: Caricature Plant.

Folk: Kaalaa-aduusaa (Maharashtra). Ysjudemaram (Tamil Nadu).

Action: Leaves—emollient and resolvent; applied to swellings and ulcers. (Used as a substitute for Adhatoda vasica).... graptophyllum picum

Grewia Populifolia

Vahl.

Synonym: G. tenax (Forsk.) Aschers & Schwf.

Family: Tiliaceae.

Habitat: Cultivated in Punjab, Sind, Rajasthan and Western India, down to the Nilgiri Hills.

Ayurvedic: Gaangeru(ki). Substitute for Gulshakari (Naagabalaa).

Siddha/Tamil: Achhu.

Folk: Gangeran.

Action: See G. hirsuta.

The stem bark contains triterpe- noids.

Dosage: Root—10-20 ml juice; 50100 ml decotion. (CCRAS.)... grewia populifolia

Microglossa Pyrifolia

(Lamk.) Kuntze.

Synonym: M. volubilis DC.

Family: Asteraceae, Compositae.

Habitat: North-eastern Indian hills.

Action: Leaf—used for ringworm of the scalp.

A acetylenic glucoside, isolated from the leaf, showed antibacterial activity against Pseudomonas aeruginosa and Staphylococcus aureus.... microglossa pyrifolia

Miel De Pulga

Molasses; also called Melaza.... miel de pulga

Muscle Pump

The contraction and relaxation of the limb muscles that helps pump the low pressure venous blood from the extremities back to the central collecting system.... muscle pump

Gunpowder Tea - A Popular Chinese Green Tea

Gunpowder tea is a Chinese tea made in Zhejiang Provence, China. It’s a form of green tea made out of withered, steamed, rolled and dried leaves. The name of gunpowder tea was given due to the fact that the small leaves which are tightly rolled into small round pellets, look like gunpowder. Gunpowder tea, like most green teas, comes from the Camellia Sinensis plant, which is a small leaved bush with many stems that can reach to almost 3 meters. There are many types of gunpowder tea, judging by the type of the leaves:
  • Pingshui gunpowder which is the most common type, has larger pellets and a more powerful flavor. It is sold as Temple of Heaven Gunpowder.
  • Formosa Gunpowder which is grown in Taiwan. Its fragrance is very close to the Taiwanese oolong tea.
  • Ceylon Gunpowder is produced at high altitudes in Sri Lanka.
Brewing Gunpowder Tea There are many ways to brew gunpowder tea, but the most handy and common preparation is by putting 1 tablespoon of gunpowder leaves for every 5 ounces of water. The gunpowder must be steeped up to 1-2 minutes into water, boiled at 160 degrees. After that, it can be streamed and served. It is not recommended to put milk or sweeteners in it such as honey or sugar, since the tea already has a soft honey flavor. What does Gunpowder Tea contain? Gunpowder tea, since it is classified as a green tea, it shares all of the components of classic green tea, mainly antioxidant ingredients such as green tea catechins (GTC). The importance of antioxidants is very high since they find and eliminate disease-causing free radicals that can develop cancer or even damage the DNA structure. Benefits of Gunpowder Tea Because antioxidants fight free-radicals, the gunpowder tea helps maintaining your general health.
  • It helps fight cancer due to the fact that antioxidants neutralize and reduce the damage that free radicals can cause to cells.
  • Prevents type II diabetes due to the fact that green tea may improve insulin sensibility and glucose tolerance.
  • It can also be used for treating loose digestion or indigestion. The antioxidants help reduce inflammations that are associated with ulcerative colitis and Chron’s disease.
  • Heals wounds and controls bleeding because of the strong fluoride content.
  • Slows aging process.
Gunpowder Tea side effects The general side effects that gunpowder tea can have are the same as the ones normal green tea present, such as nausea or stomach ache. Since it has caffeine,gunpowder tea can cause insomnia, nervousness or irritability, so avoid drinking it in the evening or before bed. Also it can cause iron deficiency, which is why people who take iron supplements are strongly advised not to drink any type of green tea, or to drink it at least 2 hours before taking the supplements or 4 hours after taking them. All in all, gunpowder tea has more benefits for your health than side effects.  It is good to drinkgunpowder tea, because it helps your immune system and provides you with all the vitamins you need in order to stay healthy.... gunpowder tea - a popular chinese green tea

Gynura Pseudo-china

(L.) DC.

Synonym: G. nudicaulis Arn.

Family: Asteraceae, Compositae.

Habitat: Eastern Himalaya, Sikkim, Assam, and Western Ghats in Tamil Nadu and Kerala.

Action: Plant—emollient, resolvent. Used as a poultice in erysipelas and for tumours in the breast. Root—used both externally and internally for enhancing blood circulation especially when blue spots and blotches result from blows. The powdered root, mixed with tea, is given to parturient women. Leaves—used for poulticing pimples. The juice is used asa gargle for inflammations of the throat.... gynura pseudo-china

Health-care Priorities

As the needs and demands of patients, and the costs of health care of populations, have risen sharply in recent years, governments and health-care providers – whether tax-funded, insurance-based, employer-provided or a mix of these – have had increasingly to face the dilemma of what services a country or a community can a?ord to provide. As a result, various techniques for deciding priorities of care and treatment are evolving. In the United Kingdom, priorities were for many years based on the decisions of individual clinicians who had wide freedom to prescribe the most appropriate care. Increasingly, this clinical freedom is being circumscribed by managerial, community and political decisions driven in part by the availability of resources and by what people want. Rationing services, however, is not popular and as yet no broadly agreed consensus has emerged, either in western Europe or in North America, as to how priorities can be decided that have broad community support and which can be a?orded. (See CLINICAL GOVERNANCE; EVIDENCE-BASED MEDICINE.)... health-care priorities

Myenteric Plexus

Broadly, the several neuron masses, ganglia, and nerve fiber plexus that lie in the walls of the intestinal tract, particularly the small intestine. They monitor and stimulate local muscle and glandular functions as well as blood supply, with little interface or control by the central nervous system or the autonomics. Each synapse away from the CNS gives greater autonomy, and these nerves only listen to God ... and food. This means the small intestine is relatively free of stress syndromes.... myenteric plexus

National Health Policy

See “health policy”.... national health policy

National Infection Control And Health Protection Agency

A National Health Service body intended to combat the increasing threat from infectious diseases and biological, chemical and radiological hazards. Covering England, the agency includes the Public Health Laboratory Service, the National Radiological Protection Board, the Centre for Applied Microbiology and Research, and the National Focus Group for Chemical Incidents.... national infection control and health protection agency

National Plan Of Action

A broad intersectoral master plan for attaining national health goals through implementation of a strategy. It indicates what has to be done, who has to do it, during what time-frame, and with what resources. It is a framework leading to more detailed programming, budgeting, implementation and evaluation. It specifies, in operational terms, the steps to be taken in accordance with the strategy, keeping in mind the various objectives and targets to be attained and the programmes for attaining them.... national plan of action

Have A Cup Of Pipsissewa Tea

If you’re looking for a special herbal tea, you can try pipsissewa tea. It has a pleasant taste, slightly bitter, like most herbal teas, but also a bit sweet. Also, it comes with many health benefits. Read to find out more!

About Pipsissewa Tea

Pipsissewa tea is made from the pipsissewa plant, also known as Umbellate Wintergreen or Prince’s pine. It is a small, evergreen perennial plant, usually found in the dry woodlands or sandy soils of Southern Canada and northern United States.

The plant can grow up to 30cm tall. It usually has 4 evergreen, shiny leaves with a toothed margin; they’re arranged one opposite the other on the stem. It has 4-8 flowers, either pink or white, which bloom during summer.

The pipsissewa plant is used to make root beer. It can also be used to flavor candies and soft drinks.

How to prepare Pipsissewa Tea

You only need a few minutes to prepare a cup of pipsissewa tea. Put a tablespoon of herbs in the cup, then pour freshly boiled water over it. Let it steep for 2-4 minutes; then, strain the drink. Sweeten it with milk or honey, if you wish.

Pipsissewa Tea Benefits

Pipsisewa, as a plant, contains many important constituents which are also transferred to the pipsissewa tea. Some of them are hydroquinones (for example, arbutin), flavonoids, triterpenes, methyl salicylate, phenols, essential oils, and tannins. They have many health benefits.

Pipsissewa teais often recommended in the treatment for infections of the urinary tract, such as cystitis, painful urination, bladder and kidney stones, kidney inflammation, prostatitis, gonorrhea, and urethritis. It can also be used to treat arthritis, gout and rheumatism.

Drinking pipsissewa tea will help your body expel various infectious microorganisms. It can increase sweating in order to treat fever diseases. It is also often included in the treatment for ailments of the respiratory tract, such as colds, whooping cough, and bronchitis.

Pipsissewa tea can be used topically, as well. It can be used with blisters, tumors, and swellings. Also, you can use it as an eye wash if you’ve got sore eyes.

Pipsissewa Tea Side Effects

It is not well-known if pipsissewa tea can affect women during pregnancy or breast feeding. However, it’s considered safe not to drink it, just in case it might affect the baby.

It is best not to drink pipsissewa tea if you’re taking medication for the intestine, or if you’ve got iron deficiency.

Drinking a large amount of pipsissewa tea can also lead to a few side effects. The symptoms you might get are: diarrhea, nausea, vomiting, headaches, and loss of appetite.

You’ll definitely enjoy drinking pipsissewa tea, both for its pleasant taste and because of the health benefits it has.

... have a cup of pipsissewa tea

Hibiscus Tea - A Popular Herbal Tea

Hibiscus tea is one of the most famous herbal tea drinks around the world. It is made from the red hibiscus flower, which is dried and steeped. Hibiscus tea can be drank either hot or cold and it is recognized for being a strong allied in the weight loss process. Hibiscus tea contains organic acids such as citric acid, malic acid and tartaric acid. This tea can be taken as a traditional supplement or as a natural medicine since it produces Vitamin C and minerals. How to make Hibiscus tea To prepare a perfect cup of hibiscus tea, first of all you will need to boil the water into a kettle. Then measure 2 teaspoons of hibiscus flowers or more if you want a stronger flavor. After the water is boiled, place the hibiscus flowers into the kettle and let it steep for about 10 minutes. Then pour the tea into a cup using a strainer to catch the hibiscus flowers. To enhance the flavor, you can always add lemon juice, sugar or even cinnamon. Hibiscus Tea benefits
  • Lowers cholesterol
  • Some studies revealed that people who suffer from type 2 diabetes may benefits from drinking this tea.
  • In Eastern medicine, hibiscus tea is used to treat liver problems
  • Due to the fact that hibiscus tea stops the body from absorbing too many carbohydrates, it is a string allied in the weight loss process.
  • Since it contains Vitamin C, hibiscus tea helps preventing colds, flu and also, strengthens your immune system.
Hibiscus tea side effects
  • Pregnant and breastfeeding women should avoid drinking hibiscus tea.
  • People with low blood pressure are not advised to drink hibiscus tea.
  • You should be careful if you want to drink hibiscus tea for the first time since it can (rarely) produce hallucinogenic effects or even cause a sensations similar to intoxication.
  • If you are taking any type of anti-inflammatories and want to drink hibiscus tea, drink it two hours after taking the medicine.
Hibiscus tea makes a wonderful drink either on cold winter days or on hot summer days, since it can be consumed either hot or cold. Enjoy its benefits and try not to experience any of its side effects!... hibiscus tea - a popular herbal tea

Needs-based Planning

Planning processes which involve the allocation of resources on the basis of community need.... needs-based planning

Non-profit / Not-for-profit Organization

An incorporated organization from which its shareholders or trustees do not benefit financially.... non-profit / not-for-profit organization

Non-proprietary Name

See GENERIC DRUG; APPROVED NAMES FOR MEDICINES.... non-proprietary name

Norfolk Island Pine

Protection, anti hunger ... norfolk island pine

Nucleus Pulposus

The inner core of an intervertebral disc. (See SPINAL COLUMN.)... nucleus pulposus

Old People (old Old)

Persons aged 75 to 84 years in a categorization of “young old” (60-74) and “oldest old” as 85 years and over.... old people (old old)

Older Person

A person who has reached a certain age that varies among countries but is often associated with the age of normal retirement.... older person

Hypericum Perforatum

Linn.

Family: Hypericaceae.

Habitat: Temperate Western Himalayas from Kashmir to Shimla at 2,000-3,000 m.

English: Common St. John's wort.

Unani: Heufaariqoon, Bassant, Balsaan.

Action: Antidepressant, sedative, relaxing nervine, anti-inflammatory. Used in anxiety, stress, depression, menopausal nervousness, menstrual cramps, neuralgia and rheumatism.

Key application: Psychovegetative disturbances, depressive moods, anxiety and or nervous unrest. Externally, oil preparation for treatment and post-therapy of acute and contused injuries, myalgia and first degree burns. (German Commission E, ESCOP, British Herbal Pharmocopoeia.)

The herb contains hypericin and pseudohypericin (0.0095 to 0.466% in the leaves and as much as 0.24% in the flowers), rutin, quercetin, hyperoside, methylhesperidin, caffeic, chloro- genic, p-coumaric, ferulic, p-hydroxy- benzoic and vanillic acids.

Plant's standardized extract (0.3% hypericin) shows antidepressant activity by inhibiting MAO.

A biflavonoid, amentoflavone, isolated from the plant, exhibited anti- inflammatory and antiulcerogenic activity.

Alcoholic extract of the plant shows in vivo hepatoprotective activity in rodents.

The oily extract of the flowers have been found effective in wound-healing due to the antibiotically active acyl- phlorogucinol, hyperforin.

The aerial parts show significant antibacterial activity against several Gram-positive and Gram-negative bacteria.

A lyophilized infusion from the aerial parts exhibited antiviral activity and inhibited reproduction of different strains of influenza virus types A and B both in vivo and in vitro.

The whole herb is effective against many viral infections.... hypericum perforatum

Idiopathic Thrombocytopenic Purpura (itp)

Sometimes described as thrombocytopenia, this is an autoimmune disorder in which blood PLATELETS are destroyed. This disturbs the blood’s coagulative properties (see COAGULATION) and spontaneous bleeding (PURPURA) occurs into the skin. The disease may be acute in children but most recover without treatment. Adults may develop a more serious, chronic variety which requires treatment with CORTICOSTEROIDS and sometimes SPLENECTOMY. Should the disease persist despite these treatments, intravenous immunoglobulin or immunosuppressive drugs (see IMMUNOSUPPRESSION) are worth trying. Should the bleeding be or become life-threatening, concentrates of platelets should be administered.... idiopathic thrombocytopenic purpura (itp)

Ilex Paraguariensis

St.-Hil.

Family: Aquifoliaceae.

Habitat: Native to South America; cultivated in some Indian gardens. In northern India, grows in Lucknow.

English: Mate Tea, Yerba Mate. Paraguay Tea.

Action: Stimulant to brain and nervous system, mild antispasmod- ic, eliminates uric acid. Used for physical exhaustion, rheumatism, gout and nervous headache. (A national drink of Paraguay and Brazil.) Causes purging and even vomiting in large doses.

Key application: In physical and mental fatigue. (German Commission E, WHO.) In fatigue, nervous depression, psychogenic headache especially from fatigue, rheumatic pains. (The British Herbal Pharmacopoeia.) German Commission E reported analeptic, positively inotropic, positively chronotropic, glycogenolytic, lipolytic and diuretic properties.

The leaves contain xanthine derivatives, including caffeine (0.2-2%), theobromine (0.3-00.5%), theophylline (absent in some samples), polyphe- nolics, tannins and chlorogenic acid, vanillin, vitamin C, volatile oil. Used in the same way as tea, due to its caffeine and theobromine content.

Mate is a world famous tea and is commonly consumed in several South American countries.

The flavour constituents exhibited moderate to weak broad-spectrum antimicrobial activity against several Gram-positive bacteria. Some components are bactericidal, particularly against the most carcinogenic bacteria, Streptococcus mutans.... ilex paraguariensis

Indigofera Pulchella

Roxb. in part.

Synonym: I. cassioides Rottl. ex DC.

Family: Fabaceae.

Habitat: The hills in India.

Ayurvedic: Nili (related species).

Siddha/Tamil: Nirinji.

Action: Root—used for cough. Powder of the root applied externally for muscular pain in chest.

Leaves and roots—used for swelling of the stomach.

The seeds contain crude protein 27.6, pentosans 8.9 and water soluble gum 12.8%.... indigofera pulchella

Oldest Old Person

Persons aged 85 years and over in a categorization of “young old” (60-74) and “old old” (75-84).... oldest old person

Ottawa Charter For Health Promotion

The Ottawa Charter for Health Promotion of 1986 identifies three basic strategies for health promotion. These are advocacy for health to create essential conditions for health; enabling all people to achieve their full health potential; and mediating between the different interests in society in the pursuit of health. These strategies are supported by five priority action areas: build health public policy; create supportive environments for health; strengthen community action for health; develop personal skills; and reorient health services.... ottawa charter for health promotion

Out-of-pocket Payment

A fee paid by the consumer of health services directly to the provider at the time of delivery.... out-of-pocket payment

Paavna

(Hindi) One who is pure; chaste Pavna, Paavnah, Pavnah, Paavani, Pavani, Pavany, Pavaney, Pavanie, Pavanee, Pavanea... paavna

Intermittent Positive Pressure (ipp)

The simplest form of intermittent positive-pressure ventilation is mouth-to-mouth resuscitation (see APPENDIX 1: BASIC FIRST AID) where an individual blows his or her own expired gases into the lungs of a non-breathing person via the mouth or nose. Similarly gas may be blown into the lungs via a face mask (or down an endotracheal tube) and a self-in?ating bag or an anaesthetic circuit containing a bag which is in?ated by the ?ow of fresh gas from an anaesthetic machine, gas cylinder, or piped supply. In all these examples expiration is passive.

For more prolonged arti?cial ventilation it is usual to use a specially designed machine or ventilator to perform the task. The ventilators used in operating theatres when patients are anaesthetised and paralysed are relatively simple devices.They often consist of bellows which ?ll with fresh gas and which are then mechanically emptied (by means of a weight, piston, or compressed gas) via a circuit or tubes attached to an endotracheal tube into the patient’s lungs. Adjustments can be made to the volume of fresh gas given with each breath and to the length of inspiration and expiration. Expiration is usually passive back to the atmosphere of the room via a scavenging system to avoid pollution.

In intensive-care units, where patients are not usually paralysed, the ventilators are more complex. They have electronic controls which allow the user to programme a variety of pressure waveforms for inspiration and expiration. There are also programmes that allow the patient to breathe between ventilated breaths or to trigger ventilated breaths, or inhibit ventilation when the patient is breathing.

Indications for arti?cial ventilation are when patients are unable to achieve adequate respiratory function even if they can still breathe on their own. This may be due to injury or disease of the central nervous, cardiovascular, or respiratory systems, or to drug overdose. Arti?cial ventilation is performed to allow time for healing and recovery. Sometimes the patient is able to breathe but it is considered advisable to control ventilation – for example, in severe head injury. Some operations require the patient to be paralysed for better or safer surgical access and this may require ventilation. With lung operations or very unwell patients, ventilation is also indicated.

Arti?cial ventilation usually bypasses the physiological mechanisms for humidi?cation of inspired air, so care must be taken to humidify inspired gases. It is important to monitor the e?cacy of ventilation – for example, by using blood gas measurement, pulse oximetry, and tidal carbon dioxide, and airways pressures.

Arti?cial ventilation is not without its hazards. The use of positive pressure raises the mean intrathoracic pressure. This can decrease venous return to the heart and cause a fall in CARDIAC OUTPUT and blood pressure. Positive-pressure ventilation may also cause PNEUMOTHORAX, but this is rare. While patients are ventilated, they are unable to breathe and so accidental disconnection from the ventilator may cause HYPOXIA and death.

Negative-pressure ventilation is seldom used nowadays. The chest or whole body, apart from the head, is placed inside an airtight box. A vacuum lowers the pressure within the box, causing the chest to expand. Air is drawn into the lungs through the mouth and nose. At the end of inspiration the vacuum is stopped, the pressure in the box returns to atmospheric, and the patient exhales passively. This is the principle of the ‘iron lung’ which saved many lives during the polio epidemics of the 1950s. These machines are cumbersome and make access to the patient di?cult. In addition, complex manipulation of ventilation is impossible.

Jet ventilation is a relatively modern form of ventilation which utilises very small tidal volumes (see LUNGS) from a high-pressure source at high frequencies (20–200/min). First developed by physiologists to produce low stable intrathoracic pressures whilst studying CAROTID BODY re?exes, it is sometimes now used in intensive-therapy units for patients who do not achieve adequate gas exchange with conventional ventilation. Its advantages are lower intrathoracic pressures (and therefore less risk of pneumothorax and impaired venous return) and better gas mixing within the lungs.... intermittent positive pressure (ipp)

Intracranial Pressure

This is the pressure that is maintained by the brain tissue, intracellular and extracellular ?uid, cerebrospinal ?uid and blood. An increase in intracranial pressure may occur as a result of in?ammation, injury, haemorrhage, or tumour in the brain tissue as well as of some congenital conditions. The pressure is measured by lumbar puncture in which a syringe attached to a mamometer (pressure-measuring device) is inserted into the cerebrospinal ?uid surrounding the lower part of the spinal cord. Where continuous pressure monitoring is necessary, an in-dwelling device can be implanted into a cerebral ventricle. Normal pressure is around 10 mm of mercury (Hg), with the acceptable upper limit being 25 mm Hg.... intracranial pressure

Pabiola

(Spanish) A little girl Pabiolla, Pabiolah, Pabiollah, Pabyola, Pabeola, Pabeolla, Pabyolla... pabiola

Paca

(Spanish) One who is free... paca

Pace

(American) A charismatic young woman Paice, Payce, Paece, Pase, Paise, Payse, Paese... pace

Pacific Man-o’war

The colloquial term for the multi-tentacled hydrozoan colony Physalia physalis, recentlydescribed on the eastern coast of Australia.... pacific man-o’war

Pacifica

(Spanish) A peaceful woman Pacifika, Pacyfyca, Pacyfyka, Pacifyca, Pacifyka, Pacyfica, Pacyfika... pacifica

Packard

(German) From the brook; a peddler’s pack

Packarde, Pakard, Pakarde, Pacard, Pacarde... packard

Pacquita

(Latin) One who is unbounded; free; independent

Pacquitah, Pacquyta, Pacqueta, Paquita, Paqueta, Pakita, Packita... pacquita

Ipomoea Petaloidea

Choisy.

Operculina petaloidea

Family: Convolvulaceae.

Habitat: Throughout India; ascending to 300 m.

Ayurvedic: Shyaamaa, Chhaa- galaantri, Vriddhadaaraka, Vrid- dhadaaru. Argyreia nervosa (Burm. f.) Boj., synonym A. spiciosa Sweet, Convolvulaceae, is equated with Vriddhadaaru and Vriddhadaaruka, while Ipomoea petaloidea and I. pes-caprae are also known by identical synonyms. Operculina turpethum, synonym I. turpethum is used as a substitute for I. petaloidea.

Unani: Shaaraf.

Siddha: Nilapoosani.

Folk: Bidhaaraa, Nishoth (black var.)

Action: Purgative. Used as a supporting herb for diseases of the nervous system.

Dosage: Leaf, root—3-6 g powder; leaf juice—5-10 ml. (CCRAS.)... ipomoea petaloidea

Ipomoea Purga

Hayne.

Synonym: I. jalapa Scheide and Deppe.

Exogonium purga (Hayne) Benth.

Family: Convolvulaceae.

Habitat: Cultivated in the Nilgiris and Poona.

English: Jalap.

Folk: Jalaapaa.

Action: Strong cathartic and purgative. Usually used with carminatives.

Resin from dried root (commercial jalap) contains beta-D-quinovoside of 11-OH-tetradecanoic acid. The glycosi- dal resin is known as "convolvulin'l... ipomoea purga

Ipomoea Purpurea

(Linn.) Roth.

Family: Convolvulaceae.

Habitat: Native of tropical America; found throughout greater part of India, grown in gardens.

English: Tall Morning-Glory.

Folk: Karakatiyaa (seeds).

Action: Purgative. Seed extract— antibacterial.

The stem contains a soft resin (4.8%), essential oil (0.08%) and tannin. The resin is the active principle, it contains ipuranol, which is identical with sitosterol glucoside, ipurolic acid, d- methyl acetic acid, hydroxylauric acid and glucose.... ipomoea purpurea

Ixora Pavetta

Andr.

Synonym: I. Parviflora Vahl.

Family: Rubiaceae.

Habitat: West Bengal, Bihar, Western Central and South India.

English: Torchwood Tree.

Ayurvedic: Nevaari, Nevaali, Ishwara, Rangan.

Siddha/Tamil: Shulundu-kora, Korivi.

Action: Flowers—pounded with milk, for whooping cough. Bark—a decoction for anaemia and general debility. Fruit and root—given to females when urine is highly coloured. The leaves contain ixoral and beta- sitosterol. Leaves and flowers gave flavonoids—rutin and kaempferol- 3-rutinoside; stems gave a flavone glycoside, chrysin 5-O-beta-D- xylopyranoside. The aerial parts contain 6,7-dimethoxycoumarin. The seed oil gave capric, lauric, myristic, palmitic, stearic, arachidic, behenic, oleic and linoleic acids.... ixora pavetta

Jateorhiza Palmata

Miers.

Synonym: J. calumba Miers.

Family: Menispermaceae.

Habitat: Indigenous to south-east tropical Africa. Imported into India.

English: Calumba, Colombo.

Ayurvedic: Kalambaka. (Coscinium fenestratum Colebr., known as False calumba, is used as a substitute for J. palmata.)

Siddha/Tamil: Kolumbu.

Action: Root—bitter tonic without astringency, carminative, gastric tonic, antiflatulent, hyptotensive, orexigenic, uterine stimulant, sedative. Used in anorexia, poor digestion, hypochlorhydria, amoebic dysentery and menstrual disorders. Antifungal.

Key application: As appetite stimulant. (The British Herbal Pharmacopoeia.)

The root gave isoquinoline alkaloids 2-3%; palmatine, jaterorrhizine and its dimer bis-jateorrhizine, columbamine; bitters (including chasmanthin and palmanin). Volatile oil contains thymol.

The alkaloid jateorrhizine is sedative, hypotensive. Palmatine is a uterine stimulant.

As calumba contains very little volatile oil and no tannins, it is free from as- tringency which is common with other bitter herbs.

The root alkaloids exhibit narcotic properties and side effects similar to morphine. It is no longer used (in Western herbal) as a digestive aid, and is rarely used as an antidiarrhoeal agent. (Natural Medicines Comprehensive Database, 2007.)... jateorhiza palmata

Padgett

(French) One who strives to better herself

Padget, Padgette, Padgete, Padgeta, Padgetta, Padge... padgett

Padma

(Hindi) Resembling the lotus flower; in Hinduism, another name for the goddess Lakshmi

Padmah, Padmia, Padmini, Padminia, Padmea, Padminea... padma

Paederasty

A homosexual act between an adult man and a boy or young man (see HOMOSEXUALITY).... paederasty

Paediatrician

A medical specialist skilled in the care of children’s health and diseases.... paediatrician

Kalanchoe Pinnata

(Lam.) Pers.

Synonym: Bryophyllum pinnatum (Lam.) Oken. B. calycinum Salisb.

Family: Crassulaceae.

Habitat: Throughout the warm and moist parts of India, especially abundant in West Bengal.

Ayurvedic: Parnabija, Pattharchuur, Pattharchat, Hemsaagar. (Paashaa- nabheda is a misleading synonym.)

Unani: Zakhm-e-Hayaat.

Siddha/Tamil: Runakalli.

Action: Leaf—anti-inflammatory, antifungal, antibacterial. Applied to wounds, burns, boils, swellings.

The methanolic extract of leaves exhibited potent anti-inflammatory activity against both exudative and proliferative phases of inflammation. The leaf extract also showed analgesic activity.

The leaves gave flavonoids—querce- tin, kaempferol, quercetin-3-diarabi- noside andkaempferol-3-glucoside; also n-hentriacontane, n-tritriacontane, alpha- and beta-amyrin and sitosterol; p-coumaric, ferulic, syringic, caffeic and p-hydroxybenzoic acids.... kalanchoe pinnata

Kigelia Pinnata

(Jacq.) DC.

Synonym: K. africana (Lam.) Benth.

Family: Bignoniaceae.

Habitat: Native to West Africa, cultivated as a roadside tree.

English: Common Sausage tree.

Folk: Jhaar Phaanuus.

Action: Bark—antidysenteric, antirheumatic, diuretic. Used in venereal diseases. Fruits— purgative.

The root bark contains monoter- penoids, pinnatal, isopinnatal and iso- kigelinol napthoquinones.

The fruit gave a cytostatic compound.

In Africa, the root bark is used in the treatment of venereal diseases, haemorrhoids and rheumatism; also as a vermifuge.... kigelia pinnata

Kingiodendron Pinnatum

(Roxb. ex DC.) Harms.

Synonym: Hardwickia pinnata Roxb. ex DC.

Family: Caesalpiniaceae.

Habitat: Hills of Tamil Nadu, Karnataka and Kerala.

English: Piney.

Ayurvedic: Samparni.

Siddha/Tamil: Kodapalai, Ma- dayansambrani.

Action: Oleo-gum-resin—used in catarrhal conditions of the genitourinary and respiratory tracts; also for treating sores.

The oleo-gum-resin contains mono- terpenes and diterpenes—hardwickiic, kolavic, kolavenic acids and kolavenol.... kingiodendron pinnatum

Lagerstroemia Parviflora

Roxb.

Family: Lythraceae.

Habitat: Almost throughout India, up to an altitude of 900 m, in the

Ayurvedic: Siddhaka, Siddha, Syandana (provisional synonym).

Folk: Dhauraa, Bakli. Chungi (Hyderabad). Lendia (trade).

Action: Astringent, fungitoxic.

The bark and leaves contain tannin 7-10 and 16% respectively. The plant contains a pentacyclic triterpene, lag- florin. Aqueous extract of fresh and ethanolic extract of dried and powdered leaves exhibit fungitoxic activity against several fungal pathogens of rice.... lagerstroemia parviflora

Pageant

(American) A dramatic woman Pagent, Padgeant, Padgent... pageant

Pahana

(Native American) A lost white- skinned sibling

Pahanah, Pahanna, Pahann, Pahanne, Pahane, Pahan... pahana

Paige

(English) A young assistant Page, Payge, Paege... paige

Long Pepper

Piper longum

Piperaceae: San: Pippali;

Hin, Ben, Pun: Piplamul; Kan, Mal:Thippali ;

Tam: Thippili; Mar: Pimpli;

Tel: Pipppaloo; Ass: Piplu.

Introduction: Long pepper is a slender aromatic climber whose spike is widely used in ayurvedic and unani systems of medicine particularly for diseases of respiratory tract. Pipalarishta, Pippalyasava, Panchakola, Pippalayadilauha, and Lavana bhaskar churan are common ayurvedic preparations made out of the dry spikes of female types. Ittrifal fauladi, Angaruya-i-kabir and Majun khadar are well known unani preparations of long pepper. Its roots also have several medicinal uses. The root is useful in bronchitis, stomach ache, diseases of spleen and tumours. Fruit is useful in vata and kapha, asthma, bronchitis, abdominal complaints, fever, leucoderma, urinary discharges, tumours, piles, insomnia and tuberculosis. Root and fruit are used in gout and lumbago. The infusion of root is prescribed after parturition to induce the expulsion of placenta. The root and fruit decoction are used in acute and chronic bronchitis and cough. It contains the alkaloid piperine which has diverse pharmacological activities, including nerve depressant and antagonistic effect on electro- shock and chemo -shock seizures as well as muscular incoordination.

Distribution: The plant is a native of Indo-Malaya region. It was very early introduced to Europe and was highly regarded as a flavour ingredient by the Romans. The Greek name “Peperi”, the Latin “Piper” and the English “Pepper” were derived from the Sanskrit name “Pippali”. It grows wild in the tropical rain forests of India, Nepal, Indonesia, Malaysia, Sri lanka, Rhio, Timor and the Philippines. In India, it is seen in Assam, West Bengal, Uttar Pradesh, Madhya Pradesh, Maharashtra, Kerala, Karnataka.and Tamil Nadu. It is also cultivated in Bengal, Chirapunchi area of Assam, Akola-Amravati region of Maharashtra, Anamalai hills of Tamil Nadu, Orissa, Uduppi and Mangalore regions of Karnataka. Bulk of Indian long pepper comes from its wild growth in Assam, Shillong and West Bengal, supplemented by imports from Sri Lanka and Indonesia (Viswanathan,1995)

Botany: Piper longum Linn. is a member of Piperaceae family. The plant is a glabrous perennial under-shrub with erect or sub-scandent nodose stem and slender branches, the latter are often creeping or trailing and rooting below or rarely scandent reaching a few metres height. Leaves are simple, alternate, stipulate, and petiolate or nearly sessile; lower ones broadly ovate, cordate; upper ones oblong, oval, all entire, smooth, thin with reticulate venation; veins raised beneath. It flowers nearly throughout the year. Inflorescence is spike with unisexual small achlamydeous densely packed flowers and form very close clusters of small greyish green or darker grey berries. Female spikes with short thick stalk varying from 1.5 to2.5 cm in length and 0.5 to 0.7 cm in thickness.

A number of geographical races are available in different agroclimatic regions of India; the most popular being Assam, West Bengal and Nepal races. Piper officinarum DC; syn. Chavica officinarum Miquel, Piper pepuloides and Piper chaba Hunter are the other related species of importance.

Agrotechnology: Long pepper is a tropical plant adapted to high rainfall areas with high humidity. An elevation of 100-1000 m is ideal. It needs partial shade to the tune of 20-30% for best growth. The natural habitat of the plant is on the borders of streams. It is successfully cultivated in well drained forest soils rich in organic matter. Laterite soils with high organic matter content and moisture holding capacity are also suitable for cultivation.

Long pepper is propagated by suckers or rooted vine cuttings.15-20 cm long 3-5 nodded rooted vine cuttings establishes very well in polybags. The best time for raising nursery is March-April. Normal irrigation is given on alternate days. The rooted cuttings will be ready for transplanting in 2 months time. With the onset of monsoon in June the field is ploughed well and brought to good tilth. 15-20 cm raised beds of convenient length and breadth are taken. On these beds, pits are dug at 60 x 60 cm spacing and well decomposed organic manure at 100 g/pit is applied and mixed with the soil. Rooted vine cuttings from polybags are transplanted to these pits. Gap filling can be done after one month of planting.The crop needs heavy manuring at the rate of 20 t FYM/ha every year. Application of heavy dose organic matter and mulching increase water retention in the soil and control weeds. Small doses of chemical fertilisers can also be used. The crop needs irrigation once a week. Sprinkler irrigation is ideal. With irrigation the crop continues to produce spikes and off-season produce will be available. However, it is reported that unirrigated crop after the onset of monsoon grows vigorously and shows much hardiness than the irrigated crop.

Crop losses can be heavy due to pests and diseases. Mealy bugs and root grubs, attack the plant particularly during summer. Infested plants show yellowing and stunted growth. Application of systemic insecticides like nuvacron or dimecron will control the pests. Adults and nymphs of Helopeltis theivora severely feeds on the foliage which can be controlled by 0.25% neem kernel suspension. Rotting of leaves and vines during monsoon season is caused by Colletotrichum glorosporiodes and necrotic lesions and blights on the leaves during summer is caused by Colletotrichum and Cercospora spp. These diseases can be controlled by spraying of 1% Bordeaux mixture repeatedly. A virus like disease characterised by yellowing and crinkling of leaves, stunted growth and production of spikes of smaller size and inferior quality was also recently reported.

The vines start flowering six months after planting and flowers are produced almost throughout the year. The spikes mature in 2 months time. The optimum stage of harvest is when the spikes are blackish green. The pungency is highest at this stage. Spikes are hand picked when they become mature and then dried. The yield of dry spike is 400 kg /ha during first year, increases to 1000kg during third year and thereafter it decreases. Therefore, after 3 years the whole plant is harvested. The stem is cut close to the ground and roots are dug up. Average yield is 500 kg dry roots/ha (Viswanathan,1995).

Piper longum can also be cultivated as an intercrop in plantations of coconut, subabul and eucalyptus.

Post harvest technology: The harvested spikes are dried in sun for 4-5 days until they are perfectly dry. The green to dry spike ratio is 10:1.5 by weight. The dried spikes have to be stored in moisture proof containers. Stem and roots are cleaned, cut into pieces of 2.5-5 cm length, dried in shade and marketed as piplamool. There are three grades of piplamool, based on the thickness. The commercial drug consists 0.5-2.5 cm long ,0.5-2.5 mm thick, cylindrical pieces dirty light brown in colour and peculiar odour with a pungent bitter taste, producing numbness to the tongue.

Properties and activity: The spike of long pepper contains 4-5% piperine, piplartin, piperolactam, N-isobutyl deca trans-2-trans-4-dienamide and piporadione alkaloides, besides 0.7 % essential oil. Roots gave the alkaloids piperine, piperlongumine (piplartine) and piperlonguminine; sesamine, methyl 3, 4, 5-trimethoxy cinnamate. Stem gave triacoutane 22, 23 - dihydrostigmasterol. Fruit essential oil contains piperidine, caryophyllene and sesquiterpene alcohol (Atal et al, 1975).

The root is plungent, hot, stomachic, laxative, anthelmintic and carminative. The fruit is sweetish, pungent, hot, stomachic, aphrodisiac, alterative, laxative, antidysenteric, emmenagogue, abortifacient, diuretic and tonic. The essential oil is antimicrobial and anthelmintic.

N-isobutyl-deca-trans-2-trans-4-dienamide is antitubercular.

Piperine is hypotensive, antipyretic, analeptic, and nerve stimulant (Warrier et al, 1995).... long pepper

Long-term Supportive Psychotherapy

is needed for patients with personality disorders or recurrent psychotic states, where the aim of treatment is to prevent deterioration and help the patient to achieve an optimal adaptation, making the most of his or her psychological assets. Such patients may ?nd more profound and unstructured forms of therapy distressing.

Behavioural therapy and cognitive therapy, often carried out by psychologists, attempt to clarify with the patient speci?c features of behaviour or mental outlook respectively, and to identify step-by-step methods that the patient can use for controlling the disorder. Behaviour therapy is commonly used for AGORAPHOBIA and other phobias, and cognitive therapy has been used for depression and anxiety. (See MENTAL ILLNESS.)... long-term supportive psychotherapy

Loranthus Pentandrus

Linn.

Synonym: Dendrophthoe pentandra (Linn.) Miq.

Family: Loranthaceae.

Habitat: Sylhet. (A parasite found on trees.)

Ayurvedic: Bandaaka (var.).

Folk: Baandaa.

Action: Leaves—used as poultice for sores and ulcers. The twigs contain quercitrin and a wax, which gives melissyl alcohol. The twig ash (8.95%) contains manganese (0.26%).... loranthus pentandrus

Mallotus Philippensis

Muell.-Arg.

Family: Euphorbiaceae.

Habitat: Throughout tropical regions of India.

English: Kamala tree, Monkey Face tree.

Ayurvedic: Kampillaka, Kampilla, Karkash, Raktaanga, Rechan, Chandra.

Unani: Kamilla, Kambilaa.

Siddha/Tamil: Kapli, Kalupatti.

Action: Gland and hair of fruit— purgative, anthelmintic, styptic. Used for the treatment of tapeworm infestation; in scabies, ringworm, herpes. Fruit—hypoglycaemic, spasmolytic, antibacterial.

Capsule hair and glands gave phlo- roglucinol derivatives; rottlerin, isorot- tlerin, iso-allorottlerin (the "red compound") and methylene-b¿s-methyl- phloroacetophenone (the "yellow compound"). The red powder, obtained from capsules, containing largely resinous matter, had lithotropic effect in rats, comparable to drugs used commonly against urinary calculi. Two more compounds designated as kama- lins 1 and 2 have been isolated.

The stem bark contains kamaladiol- 3-acetate and friedelin.

Dosage: Glands and hairs of the fruit—0.5-1.0 g powder. (API, Vol.I.)... mallotus philippensis

Malus Pumila

Mill.

Synonym: M. domestica Borkh. M. sylvestris Hort. non-Mill. Pyrus malus Linn. in part.

Family: Rosaceae.

Habitat: Native to Europe and West Asia; now cultivated in Himachal Pradesh., Kashmir, Kulu, Kumaon, Assam and in the Nilgiris.

English: Cultivated Apple.

Ayurvedic: Sinchitikaa.

Folk: Seb, Sev.

Action: Bark—anthelmintic, refrigerant, hypnotic, given in intermittent, remittent and bilious fevers. Leaves—inhibit the growth of a number of Gram-positive and Gram-negative bacteria.

The fruit contains malic (90-95% of the total acids), citric, lactic and succinic acids; (unripe fruit contains quinic acid, citric acid, succinic acid, lactic acid); caffeic acid derivatives, pectins, minerals and vitamins.

Edible portion of fresh apple contains thiamine 0.12, riboflavin 0.03, niacin 0.2 and ascorbic acid 2 mg/100 g. The ascorbic acid content varies widely and values up to 40 mg/100 g. Sugars constitute about 80% of the total carbohydrates of ripe fruits—fructose (60), glucose (25) and sucrose (15%). The pectin content of the edible portion varies from 0.14 to 0.96% (as calcium pectate). The uronic acid content of apple pectin varies from 0.5 to 15%.

The astringent principles of apple include tannins, tannin derivatives and colouring materials (flavones). The browning of apple slices on exposure to air is due to enzymic oxidation of tannin compounds.

Fresh juice contains 0.20-0.80 malic acid, 11.6 total sugars and 0.02100.080% tannin.

The seeds contain cyanogenic gly- coside, amygdalin (0.62-1.38%, HCN equivalent, 0.037-00.087%).... malus pumila

Pain Management Programme

A set of strategies to address an individual’s pain management requirements and supportive of the individual’s pain control.... pain management programme

Paisley

(English) Woman of the church Paisly, Paisli, Paislie, Paislee, Paysley, Paysly, Paysli, Payslie, Payslee, Pasley, Pasly, Pasli, Paslie, Paslee, Paizley, Payzley, Pazley, Paislea, Paizlea, Paslea, Payslea... paisley

Paiva

(Finnish) Born during daylight Paeva, Payva... paiva

Paka

(African) A catlike woman Pakah, Pakka, Packa, Pacca... paka

Mental Health Problems In Children

Emotional and behavioural problems are common in children and adolescents, affecting up to one-?fth at any one time. But these problems are often not clear-cut, and they may come and go as the child develops and meets new challenges in life. If a child or teenager has an emotional problem that persists for weeks rather than days and is associated with disturbed behaviour, he or she may have a recognisable mental health disorder.

Anxiety, phobias and depression are fairly common. For instance, surveys show that up to

2.5 per cent of children and 8 per cent of adolescents are depressed at any one time, and by the age of 18 a quarter will have been depressed at least once. Problems such as OBSESSIVE COMPULSIVE DISORDER, ATTENTION DEFICIT DISORDER (HYPERACTIVITY SYNDROME), AUTISM, ASPERGER’S SYNDROME and SCHIZOPHRENIA are rare.

Mental-health problems may not be obvious at ?rst, because children often express distress through irritability, poor concentration, dif?cult behaviour, or physical symptoms. Physical symptoms of distress, such as unexplained headache and stomach ache, may persuade parents to keep children at home on school days. This may be appropriate occasionally, but regularly avoiding school can lead to a persistent phobia called school refusal.

If a parent, teacher or other person is worried that a child or teenager may have a mental-health problem, the ?rst thing to do is to ask the child gently if he or she is worried about anything. Listening, reassuring and helping the child to solve any speci?c problems may well be enough to help the child feel settled again. Serious problems such as bullying and child abuse need urgent professional involvement.

Children with emotional problems will usually feel most comfortable talking to their parents, while adolescents may prefer to talk to friends, counsellors, or other mentors. If this doesn’t work, and if the symptoms persist for weeks rather than days, it may be necessary to seek additional help through school or the family’s general practitioner. This may lead to the child and family being assessed and helped by a psychologist, or, less commonly, by a child psychiatrist. Again, listening and counselling will be the main forms of help o?ered. For outright depression, COGNITIVE BEHAVIOUR THERAPY and, rarely, antidepressant drugs may be used.... mental health problems in children

Mentha Piperata

Linn. emend. Huds.

Family: Labiatae; Lamiaceae.

Habitat: Native to Europe; cultivated in Maharashtra, Kashmir and Punjab.

English: Peppermint, Brandy Mint.

Ayurvedic: Vilaayati Pudinaa.

Action: Oil—digestive, carminative, chloretic, antispasmodic, diuretic, antiemetic, mild sedative, diaphoretic, antiseptic, antiviral, used in many mixtures of indigestion and colic and cough and cold remedies.

Key application: Leaf—internally for spastic complaints of the gastrointestinal tract, gallbladder and bile ducts. (German Commission E, ESCOP.) The British Herbal Compendium indicates peppermint leaf for dyspepsia, flatulence, intestinal colic, and biliary disorders.

Key application: Oil—as a carminative. (The British Herbal Pharmacopoeia.) In spastic discomfort fo the upper gastrointestinal tract and bile ducts, irritable colon, the respiratory tract and inflammation of the oral mucosa. Externally, for myalgia and neuralgia. (German Commission E.) ESCOP indicates its use for irritable bowel syndrome, coughs and colds. Externally, for coughs and colds, rheumatic complaints, pruritus, urticaria, and pain in irritable skin conditions. (ESCOP.)

The essential oil has both antibacterial and antifungal properties.

The major constituents of the essential oil are: menthol, menthone, pulegone, menthofuran, 1,8-cineole, men- thyl acetate, isomenthone. The leaves contain flavonoid glycosides, erioc- itrin, luteolin 7-O-rutinoside, hesperi- din, isorhoifolin, diosmin, eriodictyol 7-O-glucoside and narirutin, besides rosmarinic acid, azulenes, cholene, carotenes.

Peppermint oil relaxed carvachol- contracted guinea-pig tenia coli, and inhibited spontaneous activity in guinea-pig colon and rabbit jejunum. It relaxes gastrointestinal smooth muscle by reducing calcium influx. Peppermint oil reduced gastric emptying time in dyspeptics.

The aqueous and ethanolic extracts exhibited antiviral activity against RPV (rinder pest virus), a highly contagious viral disease of cattle.... mentha piperata

Paki

(African) A witness of God Pakki, Packi, Pacci, Pakie, Pakkie, Paky, Pakky, Pakey, Pakkey, Pakee, Pakkee, Pakea, Pakkea... paki

Pakuna

(Native American) Resembling a deer running through the hills Pakunah, Pakoona, Packuna, Pacuna, Pakouna, Pacouna... pakuna

Pakwa

(Native American) Resembling a frog Pakwah... pakwa

Pala

(Native American) Woman of the water Palah... pala

Palakika

(Hawaiian) One who is dearly loved

Palakyka, Palakeka, Palakeeka, Palakieka, Palakeika, Palakeaka... palakika

Palani

(Hawaiian) An independent woman Pallani, Palanie, Palany, Palaney, Palanee, Pallanee, Palanea, Pallanea, Pallanie, Pallany, Pallaney... palani

Palba

(Spanish) A fair-haired woman... palba

Palemon

(Spanish) A kindhearted woman Palemond, Palemona, Palemonda... palemon

Pales

(Latin) In mythology, goddess of shepherds and flocks Paless, Palesse, Palus, Palles, Pallus... pales

Palesa

(African) Resembling a flower Palessa, Palesah, Palysa, Palisa, Paleesa... palesa

Palila

(Hawaiian) A birdlike woman Palilla, Palilah, Pallila, Pallilla, Palyla, Palylla... palila

Microcos Paniculata

Linn.

Synonym: Grewia microcos Linn. G. ulmifolia Roxb.

Family: Tiliaceae.

Habitat: North-eastern parts of India, West Bengal, Western Ghats and Andaman Islands.

Folk: Asar (Bengal); Thengprenke- orong (Assam); Kadambu, Visalam, Kottei (Tamil Nadu); Abhrangu (Karnataka).

Action: Plant—stomachic, an- tidysenteric, antisyphilitic, antibacterial (also used for smallpox and eczema).... microcos paniculata

Mitragyna Parvifolia

(Roxb.) Korth.

Family: Rubiaceae.

Habitat: All over India, and up to 1,200 m in the outer Himalaya.

English: Kaim.

Ayurvedic: Giri-kadamba, Kadamba (var.).

Siddha: Chinna-Kadambu.

Action: Bark—used for muscular pain. Bark and root—febrifuge, antispasmodic.

Both indole and oxindole alkaloids have been isolated from the plant. (The composition of alkaloids varies with season and from place to place.) The main indole alkaloid reported is akuammigine and oxindole alkaloids have been identified as mitra- phylline, isomitraphylline, pteropo- dine, isopteropodine, speciophylline and uncarine F. Anthocephalus cadamba Miq. is the accepted source of Kadamba.... mitragyna parvifolia

Moringa Pterygosperma

Gaertn.

Synonym: M. oleifera Lam.

Family: Moringaceae.

English: Drumstick, Horse-Radish.

Ayurvedic: Shigru (white var.), Madhu Shigru, Sigra, Shobhaan- jana, Haritashaaka. Raktaka, Murangi, Mochaka, Akshiva, Tikshnagandhaa.

Unani: Sahajan.

Siddha/Tamil: Murungai.

Action: All parts of the tree are reported to be used as cardiac and circulatory stimulant. Pods—antipyretic, anthelmintic; fried pods are used by diabetics. Flowers—cholagogue, stimulant, diuretic. Root juice—cardiac tonic, antiepileptic. Used for nervous debility, asthma, enlarged liver and spleen, deep-seated inflammation and as diuretic in calculus affection. Decoction is used as a gargle in hoarseness and sore throat. Root and fruit—antiparalytic. Leaf—juice is used in hiccough (emetic in high doses); cooked leaves are given in influenza and catarrhal affections. Root-bark—antiviral, anti-inflammatory, analgesic. Bark—antifungal, antibacterial. Stem-bark and flower—hypo- glycaemic. Seeds—an infusion, anti-inflammatory, antispasmodic and diuretic; given in venereal diseases.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicated the use of the dried root bark in goitre, glycosuria and lipid disorders (also dried seeds), and leaf, seed, root bark and stem bark in internal abscess, piles and fistula-in-ano.

The plant contains antibacterial principles, spirochin and pterygosper- min which are effective against both Gram-Positive and Gram-Negative bacteria.

The leaves contain nitrile glycosides, niazirin and niazirinin and mustard oil glycosides. The mustard oil glycosides showed hypotensive, bradycardiac effects and spasmolytic activity, justifying the use of leaves for gastrointestinal motility disorders.

The roots possess antibacterial, anti- choleric and antiviral properties due to the presence of pterygospermin, Spiro chin and benzylisothiocyanate. The root extract exhibited significant anti- inflammatory activity in carrageenan- induced paw-oedema in rats.

The leaves exhibited hypoglycaemic activity, although the plasma insulin level did not alter much.

The root and bark showed antifer- tility activity through biphasic action on the duration of the estrous cycle of female rats.

Dosage: Leaf—10-20 ml. juice. (API, Vol. III); root bark—2-5 g powder; stem bark—2-5 g powder; seed—5-10 g powder (API, Vol. IV). Leaf, flower, fruit, seed, bark, root— 1-3 g powder; 50-100 ml decoction. (CCRAS.)... moringa pterygosperma

Paliuli

(Polynesian) Woman from the paradise garden

Paliulie, Paliuly, Paliuley, Paliulee, Paliulea... paliuli

Pallas

(Greek) Full of wisdom and understanding; a maiden; in mythology, a friend of Athena Palla... pallas

Pallavi

(Indian) Resembling new leaves Palavi, Pallavie, Palavie, Pallavy, Palavy, Pallavey, Palavey, Pallavee, Palavee, Pallavea, Palavea... pallavi

Mucuna Prurita

Hook.

Synonym: M. pruriens Baker non DC.

Family: Papilionaceae; Fabaceae.

Habitat: Throughotu India, including Andaman and Nicobar Islands.

English: Cowhage, Horse-eye Bean.

Ayurvedic: Aatmaguptaa, Kapikac- chuu, Rshabhi, Adhigandhaa, Ajadaaa, Kacchuraa, Laan- guli, Rshyaproktaa, Svaguptaa, Shyaamguptaa, Markati, Kanduraa, Kevaanch, Shuukashimbi.

Unani: Konchh.

Siddha/Tamil: Poonaikkaali.

Action: Seed—astringent, nervine tonic, local stimulant, used in impotence, spermatorrhoea, urinary troubles, leucorrhoea, traditionally used for male virility. Also used in depressive neurosis. Hair on fruit— vermifuge, mild vesicant; used for diseases of liver and gallbladder. Leaf—applied to ulcers. Pod— anthelmintic. Root and fruit—spasmolytic, hypoglycaemic. Root— CNS active.

The Ayurvedic Pharmacopoeia ofIn- dia recommends the seed in impotence and paralysis agitans; the root in vaginal laxity.

The seeds contain the alkaloids, mu- cunine, mucunadine, mucunadinine, prurieninine, pruriendine and nicotine, besides beta-sitosterol, gluthione, lecithin, vernolic and gallic acids. They contain a number of bioactive substances including tryptamine, alky- lamines, steroids, flavonoids, cou- marins and cardenolides. L-DOPA is present in the seed as well as in the stem, leaves and roots.

Major constituents of the hairs on the pod are amines such as 5-hydroxy- tryptamine (serotonin), and a proteolytic enzyme mucuanain. (Serotonin was present only in pods.)

Prurieninine slowed down heart rate, lowered blood pressure and stimulated intestinal peristalsis in experiments carried out on frogs. The spas- molysis of smooth muscles was caused by indole bases.

Seed diet produced hypoglycaemic effect in normal rats, however, such diet had insignificant effect on alloxan- treated rats.

There is some evidence that Cow- hage might be useful for chlorproma- zine-induced hyperprolactinemia in men. (Natural Medicines Comprehensive Database, 2007.) (Males with hy- perprolactinemia frequently face im- potency.) (Cured seeds are used in Indian medicine for male sexual dysfunction.)

Mucuna cochinchinensis Cheval.; synonym M. nivea (Roxb.) DC.; Sti- zolobium niveum Kuntze (cultivated in Bengal and Bihar for edible pods and seeds) is known as Lyon Bean (Khamach in Bengal). The pod yielded L-DOPA (0.06%).

Dosage: Cured seed—3-6 g (API, Vol. III); root—3-6 g powder for decoction (API, Vol. IV.)... mucuna prurita

Musa Paradisiaca

Linn.

Synonym: M. Sapientum Linn.

Family: Musaceae.

Habitat: Assam, Madhya Pradesh, Bihar, Gujarat, Andhra Pradesh, Karnataka, Jalgaon district (Maharashtra), West Bengal, Tamil Nadu and Kerala.

English: Banana, Plantain.

Ayurvedic: Kadali, Rambhaa, Sakrtphala, Vaaranaa, Mochaa, Ambusaara, Anshumatiphal.

Unani: Kelaa, Mouz.

Siddha/Tamil: Vaazhai.

Action: Fruit—mild laxative, combats diarrhoea and dysentery, promotes healing of intestinal lesions in ulcerative colitis. Unripe fruit considered useful in diabetes. Fruit powder—used as a food supplement in sprue and other intestinal disorders. Root— anthelmintic.

The Ayurvedic Pharmacopoeia ofIn- dia recommends the fresh rhizome in dysuria, polyuria (in females) and menstrual disorders; the flower in asthma, bleeding disorders, vaginal discharges and leucorrhoea.

The pulp of ripe fruit (50 g/rat per day) given daily with standard food pellets prevented increase in blood pressure in deoxycorticosterone-in- duced hypertension in rats. This was found partially related to increased serotonin levels triggered by the high carbohydrate and tryptophan content of the fruit.

Dietary fibre prepared from unripe banana exerted an antiatherogenic effect, keeping the levels of cholesterol in serum and aorta low, as also the level of LDL cholesterol in rats fed on cholesterol diet.

An anti-ulcerogenic acylsterylgly- coside, sitoindoside IV, has been isolated from unripe banana.

A pectin containing hexoses (32.4%) and uronic acid (52.5%) has been isolated from the pith of the stem. The pectin was found to exhibit significant hypolipidaemic and hypoglycaemic activity in rats.

The flower extract exhibited hypo- glycaemic activity in rabbits.

The pseudostem is reported to possess lithotriptic and antilithic properties. The extract reduced the precursor of oxalate formation, the liver glycolic acid content in hyperoxaluric rats.

The benzene extract of the root exhibited significant antibacterial and an- tifungal activity.

Dosage: Dried flower—10-20 g. (API, Vol. IV.)... musa paradisiaca

Palm, Date

Fertility, Potency... palm, date

Palmetto Palm

Sabal palmetto

Description: The palmetto palm is a tall, unbranched tree with persistent leaf bases on most of the trunk. The leaves are large, simple, and palmately lobed. Its fruits are dark blue or black with a hard seed.

Habitat and Distribution: The palmetto palm is found throughout the coastal regions of the southeastern United States.

Edible Parts: The fruits are edible raw. The hard seeds may be ground into flour. The heart of the palm is a nutritious food source at any time. Cut off the top of the tree to obtain the palm heart.... palmetto palm

Palmira

(Spanish / Latin) Feminine form of Palmiro; a pilgrim / from the city of palm trees

Palmyra, Palmera, Palmeira, Palmiera, Palmer, Palmyr, Palma, Pameera, Palmeara... palmira

Palo De

Means “stick or wood of (plant name)”; look up the plant name which follows this description of the plant part used for medicine.... palo de

Paloma

(Spanish) Dovelike Palomah, Palloma, Palomina, Palomyna, Palomeena, Poloma, Palomeana, Palomeina, Palomiena... paloma

Nipa Palm

Nipa fruticans

Description: This palm has a short, mainly underground trunk and very large, erect leaves up to 6 meters tall. The leaves are divided into leaflets. A flowering head forms on a short erect stern that rises among the palm leaves. The fruiting (seed) head is dark brown and may be 30 centimeters in diameter.

Habitat and Distribution: This palm is common on muddy shores in coastal regions throughout eastern Asia.

Edible Parts: The young flower stalk and the seeds provide a good source of water and food. Cut the flower stalk and collect the juice. The juice is rich in sugar. The seeds are hard but edible.

Other Uses: The leaves are excellent as thatch and coarse weaving material.... nipa palm

Opioid Poisoning

MORPHINE and CODEINE are natural opium ALKALOIDS found in the opium poppy (Papaver somniferum). The other opioids are either synthetic or semi-synthetic analogues of these. Their main use is in the treatment of moderate to severe PAIN, but they are also used as antidiarrhoeal and antitussive agents. As a result of induced tolerance (see DEPENDENCE) and great individual variability, the amount of opioid substances required to cause serious consequences varies enormously.

The most common effects of opioid overdose are vomiting, drowsiness, pinpoint pupils, BRADYCARDIA, CONVULSIONS and COMA. Respiratory depression is common and may lead to CYANOSIS and respiratory arrest. HYPOTENSION occurs occasionally and in severe cases non-cardiogenic pulmonary oedema and cardiovascular collapse may occur. Cardiac ARRHYTHMIA may occur with some opioids. Some opioids have a HISTAMINE-releasing e?ect which may result in an urticarial rash (see URTICARIA), PRURITUS, ?ushing and hypotension. Activated CHARCOAL should be given following overdose and NALOXONE administered to reverse respiratory depression and deep coma.... opioid poisoning

Orange Peel Tea - A Bittersweet Tea

If you want both an aromatic tea, as well as a healthy one, orange peel tea is perfect. It is a delicious beverage, especially during cold winter days. It also helps you stay healthy, especially thanks to the amount of vitamin C it contains. Read this article to find out more about its health benefits and side effects. About Orange Peel Tea Orange peel tea is made from the peel of the orange fruit. The fruit grows in orange trees, which are cultivated all around the world. The orange peel is the outer skin of the orange, leathery-textured and with many oil glands. Orange peel, as well as the peel from other fruits (lemon, lime) has been used for medical purposes for many years. They are also used for culinary purposes, as they can be added to soups, stews, cakes or cookies. Components of Orange Peel Tea It is well-known that oranges have many nutritional components. Some are included in the orange peel, as well, and are thus transferred to the orange peel tea. The orange peel tea is, of course, a great source of Vitamin C, and also has vitamin B1. Other important active constituents are: choline, folic acid, antioxidant flavonoids, d-limonene, alpha-carotene, beta-carotene, and aldehydes. How to make Orange Peel Tea If you’ve got some oranges around, you can easily make your own orange peel tea from scratch. Peel the skin from an orange, cut it in smaller pieces, and let them dry, preferably in a cool, dry place. Once they’re dry, you can use them for your orange peel tea. Add a bit to a cup of boiling water and let it steep for about 10-15 minutes. Remove the pieces of dried orange peel and you’re ready to drink your cup of tea! Orange Peel Tea Benefits Because of its many active constituents, orange peel tea helps you stay healthy. One cup brings many health benefits. Orange peel tea helps you fight against viruses and bacteria. It is also useful when treating coughs, asthma, bronchitis, tightness in the chest, and colds. Generally, it is good at helping the body eliminate the phlegm in the lungs. Drinking orange peel tea helps you have a good digestion. It is useful when relieving gas, bloating and nausea, symptoms of an upset stomach. Also, it is drunk in order to treat constipation, and it helps boost your appetite. Orange peel tea is also helpful when it comes to having a good oral hygiene. It helps you take care and treat sensitive skin, and it also eliminates bad breath. Another benefit is related to stimulating blood circulation and the flow in the lymphatic system. Also, orange peel tea is useful with helping you fight stress, nervousness, and insomnia. For women who have just given birth, orange peel tea helps treat mastitis (when the breast feels swollen because of excess milk production). If this is your case, then it’s recommended that you drink it twice a day. Orange Peel Tea Side Effects Just like any type of tea, orange peel tea also comes with a few side effects. First, it is recommended that you not drink orange peel tea while you’re pregnant. It might cause problems to the baby. Orange peel tea can act as a stimulant in some cases. It might cause symptoms such as nervousness or restlessness, and you might also have trouble falling asleep. It will act even more as a stimulant if you take a supplement that contains caffeine. If your family has a history of heart diseases, speak to your doctor before drinking orange peel tea. It might be harmful for you, and cause high blood pressure, hypertension, arrhythmias, tachycardia, fainting, heart palpitations and chest pains. Be careful if you’re suffering from hyperthyroidism. Orange peel tea may aggravate the thyroid’s condition. It might also weaken your body, or cause vision problems. It can cause your vision to get blurry, difficulty in focusing, and it might also worsen glaucoma. Not only is orange peel tea richly aromatic and delicious, but it is also good for your health. Make sure you get no side effects and then you can enjoy a cup of orange peel tea!... orange peel tea - a bittersweet tea

Palti

(Hebrew) My escape; deliverance Paltie, Palty, Paltee, Paltey, Paltea... palti

Pamba

(African) In mythology, the mother of the people... pamba

Paeonia Emodi

Wall. ex Royle.

Family: Paeoniaceae.

Habitat: Northwestern Himalaya from Kashmir to Kumaon at 2,0003,000 m.

English: Himalayan Paeony.

Unani: Ood Saleeb, Ood Gharqi, Phaavaaniaa.

Folk: Root—used in nervous affections, uterine diseases, as a blood purifier. Flower—antidiarrhoeal. Seed—emetic, cathartic. Plant— CNS depressant, hypothermic, diuretic, anti-inflammatory.

The root contains an essential oil, with salicylaldehyde as the chief component, a fixed oil, benzoic acid and sucrose. The plant gave Gallo tannin and glucogallin.... paeonia emodi

Paeonia Officinalis

Linn.

Family: Paeoniaceae.

Habitat: Indigenous to Great Britain.

English: Paeony.

Unani: Ood Saleeb, Ood Gharqi.

Action: Root—antispasmodic, sedative, smooth muscle relaxant, vasodilatory, hypotensive, anti-inflammatory, analgesic, em- menagogue, hepatoprotective. Flower—used for diseases of mucous membranes, fissures, anal fissures associated with haemorrhoids, also for ailments of the respiratory tract, nervous conditions and skin diseases. Root— used for arthritis, neuralgia, neurasthenia, migraine, epilepsy, allergic disorders, whooping cough and painful spasms.

The herb gave monoterpene ester glucosides of the pinen-type (including paeoniflorin); anthocyanin including paeonin; tannins (pentagalloyl glucose); flavonoids including kaempferol glycosides.

Paeoniflorin shows a smooth muscle relaxant, vasodilatory, anti-inflammatory, immunostimulating and some CNS depressant activity in animal studies. Pentagalloyl glucose exhibited antiviral activity in animal studies in vitro against herpes simplex.

German Commission E included Paeony (flower and root) among un- approved herbs. The Pharmacopoeia of People's Republic of China indicates the use of the root in dementia, headache and vertigo. (WHO.)... paeonia officinalis

Pamela

(English) A woman who is as sweet as honey

Pamelah, Pamella, Pammeli, Pammelie, Pameli, Pamelie, Pamelia, Pamelea, Pamelee, Pameleigh, Pamelina, Pameleena, Pamelyna... pamela

Pamuy

(Native American) Born during the water moon... pamuy

Pana

(Native American) Resembling a partridge Panah... pana

Panagiota

(Greek) Feminine form of Panagiotis; a holy woman... panagiota

Panchali

(Indian) A princess; a highborn woman

Panchalie, Panchaly, Panchalli, Panchaley, Panchalee, Panchalea, Panchaleigh... panchali

Paget’s Disease Of Bone

Also called osteitis deformans, this is a chronic disease in which the bones (see BONE) – especially those of the skull, limbs, and spine – gradually become thick and also soft, causing them to bend. It is said to be the most common form of bone disease in the world, and it is estimated that some 600,000 people in England may suffer from it. It seldom occurs under the age of 40. Pain is its most unpleasant manifestation. The cause is not known, and there is no known cure, but satisfactory results are being obtained from the use of CALCITONIN and a group of drugs known as BISPHOSPHONATES

(e.g. etidronate). Those with the disease can obtain help and advice from the National Association for the Relief of Paget’s Disease.... paget’s disease of bone

Palate, Malformations Of

The commonest deformity of the PALATE is cleft palate, which is a result of faulty embryonic development in which the two sides of the palate fail to fuse or only fuse in part. If the cleft extends the full length with bilateral clefts at the front of the MAXILLA, it may be accompanied by a cleft lip (also called hare-lip) and disruption in the development of the front teeth. About 1 in 500 babies is born with a cleft lip and 1 in 1,000 has a cleft palate. If the parents are affected, the risk is three times that of the normal population; if one child has a deformity, the risk for a subsequent child is higher. Associated abnormalities include tongue tie, malpositioning of the MANDIBLE and ?uid in the middle EAR.

Cleft palate and hare-lip should be recti?ed by operation, because both are a serious drawback to feeding in early life – while later, harelip is a great dis?gurement, and the voice may be affected. The lip may be dealt with at any time from the neonatal period to a few weeks, depending on the individual surgeon’s view of when the best result is likely to be achieved. Prior to operation, special techniques may be necessary to ensure adequate feeding such as the use of special teats in formula-fed babies. The closure of a large cleft in the palate is a more formidable operation and is better performed when the face has grown somewhat, perhaps at 6–12 months. The operations performed vary greatly in details, but all consist in paring the edges of the gap and drawing the soft parts together across it.

Further operations may be required over the years to improve the appearance of the nose and lip, to make sure that teeth are even, and to improve speech.

Parents of such children can obtain help and advice from the Cleft Lip and Palate Association (CLAPA).... palate, malformations of

Panda

(English) Resembling the bamboo- eating animal Pandah... panda

Pandanus Utilis

Bory.

Family: Pandanaceae.

Habitat: Native of Malagasy; grown in Indian gardens.

Ayurvedic: Ketaki (related species).

Action: Root—a decoction is used for the treatment of venereal... pandanus utilis

Pandara

(Indian) A good wife Pandarah, Pandarra, Pandaria, Pandarea... pandara

Pandia

(Greek) In mythology, the personification of brightness Pandiah, Pandea, Pandiya, Pandya, Pandeah, Pandiyah, Pandyah... pandia

Pandita

(Indian) A studious woman Panditah, Pandyta, Pandeta, Pandeyta, Pandeeta, Pandeata... pandita

Pandora

(Greek) A gifted, talented woman; in mythology, the first mortal woman, who unleashed evil upon the world Pandorah, Pandorra, Pandoria, Pandorea, Pandoriya... pandora

Panax Pseudoginseng

Wall.

Family: Araliaceae.

Habitat: Western Himalayas, Pithoragarh district of Uttaranchal.

English: Indian Ginseng, Indian Pseudoginseng.

Ayurvedic: In Indian medicine, Panax quinquefolium Linn. and Panax schinseng Knees have been equated with Lakshmanaa.

Action: Adaptogen, digestive relaxant, old-age revitalizer. Sustains nerves and immune system in physical exhaustion and during convalescence. Antiarrhythmic (used for angina). Activities comparable with Korean ginseng.

Indian pseudoginseng, including subspecies himalaicus and its varieties, variety angustifolius and variety bipinnatifidus, has been found to be a rich source ofoleanolic acid saponins, while dammarane saponins (panaxa- diol and panaxatriol) are present in minor quantities. Panax burkillianus Bennet & Viswan and P. sikkimensis Banerjee are also related to the commercial ginseng.

Panax quinquefolium (American Ginseng) has been introduced into India in the Kashmir valley during 1983. It is rich in dammarane saponins. The air-dried roots of the plant, introduced in India, contain total saponin content of 11.5%. The saponins isolated include ginsenosides Rb1, Rb2, Rb3, Rc, Rd, Re, Rg1, pseudoginsenoside F11 and chikusetsu saponin V; the major saponin being ginsenoside Rb1. The saponin fraction of the root yielded panaxadiol, panaxatriol and oleanolic acid.

Ginsenosides Rb and Rc are 'diols', while Rg is a 'triol'. ('triol' group is arousing, 'diol' is sedative.) In American ginseng 'diols' predominate.

Panax pseudoginseng, equated with Himalayan ginseng (Natural Medicines Comprehensive Database, 2007), is believed to dilate the coronary vessels, re duce vascular resistance and improve the coronary collateral circulation. It increased blood flow while reducing blood pressure.

Panax schiseng, synonym P. ginseng Mey. (Asiatic or Chinese Ginseng) is cultivated in northern China, Korea and Japan.... panax pseudoginseng

Pancreas, Disorders Of

Diabetes See DIABETES MELLITUS.

Pancreatic cancer The incidence of pancreatic cancer is rising: around 7,000 cases are now diagnosed annually in the UK, accounting for 1–2 per cent of all malignancies. There is an established association with heavy cigarette-smoking, and the cancer is twice as common in patients with diabetes mellitus as compared with the general population. Cancer of the pancreas is hard to diagnose; by the time symptoms occur the tumour may be di?cult to treat surgically – with PALLIATIVE bypass surgery the only procedure.

Chronic pancreatitis may be painless; it leads to pancreatic failure causing MALABSORPTION SYNDROME and diabetes mellitus, and the pancreas becomes calci?ed with shadowing on X-RAYS. The malabsorption is treated by a low-fat diet with pancreatic enzyme supplements; the diabetes with insulin; and pain is treated appropriately. Surgery may be required.

Acute pancreatitis An uncommon disease of the pancreas which may start gradually or suddenly, usually accompanied by severe abdominal pain which often radiates through to the back. Biliary tract disease and alcohol account for 80 per cent of patients admitted with acute pancreatitis, while other causes include drugs (see AZATHIOPRINE and DIURETICS) and infections such as MUMPS. Patients are acutely ill with TACHYCARDIA, fever and low blood pressure; many go into SHOCK. The condition may be mistaken for a perforated PEPTIC ULCER, except that in acute pancreatitis the blood concentration of AMYLASE is raised. The main complication is the formation of a PSEUDOCYST. Treatment includes intravenous feeding, ANTICHOLINERGIC drugs and ANALGESICS. Regular measurements of blood GLUCOSE, CALCIUM, amylase and blood gases are required. Abdominal ULTRASOUND may identify gall-stones (see under GALL-BLADDER, DISEASES OF). If the patient deteriorates, he or she should be admitted for intensive care as haemorrhagic pancreatic necrosis may be developing. LAPAROTOMY and DEBRIDEMENT may be called for. Mortality is 5–10%.... pancreas, disorders of

Pang

(Chinese) One who is innovative... pang

Pangiota

(Greek) One who is sacred Pangyota, Pangeota... pangiota

Pani

(Polynesian) In mythology, goddess of plants and fertility

Panni, Panie, Pany, Paney, Pannie, Panee, Panea... pani

Panicle

A compound flower head that forms a raceme.... panicle

Paniz

(Persian) A girl who is as sweet as sugar

Panize, Panyz, Panez, Panizia, Panizea... paniz

Pankita

(Indian) A young girl; one who is liberal

Pankitah, Pankyta, Panketa, Pankeeta, Pankieta, Pankeita, Pankeata... pankita

Panna

(Hindi) Resembling an emerald Pannah... panna

Panola

(Greek) One who is all-knowing Panolah, Panolla, Panollah, Panolia, Panoliah, Panolea, Panoleah, Panoliya, Panoliyah... panola

Pandanus Facicularis

Lam.

Synonym: P. tectorius auct. non Soland ex Parkinson. P. odoratissimus Linn. f.

Family: Pandanaceae.

Habitat: Sea coast of the Indian Peninsula on both sides, and the Andaman Islands.

English: Screw Pine.

Ayurvedic: Ketaka, Ketaki, Suuchikaa pushpaa, Jambuka, Trinshunya, Ketakark, Krakchhada.

Unani: Keoraa.

Siddha/Tamil: Thazhai, Thalay.

Action: Flower—carminative, stomachic, cooling, antiseptic. Used for headache, ulcers, dysuria, scabies and other skin diseases. Root— used for osteoarthritis, leucorrhoea and amenorrhoea; contraindicat- ed during pregnancy. Leaves— used for skin diseases, small pox, scabies, leprosy. The Ayurvedic Pharmacopoeia of India recommends the decoction of the root in abdominal inflammation. Oil and otto—stimulant, antispasmodic, antirheumatic.

The chief constituent of the oil is methyl ether of beta-phenylethyl alcohol. The oil also contains diterpene, d-linalool, phenylethyl acetate, citral, phenylethyl alcohol, ester of phthalic acid, fatty acids and stearoptene.

The leaves contain the piperidine alkaloids.

Dosage: Root—29-30 g for decoction (API, Vol. I); flower linctus—25-30 ml. (CCRAS.).... pandanus facicularis

Panic Attacks

Panic attacks, or panic disorders, are recurrent short episodes of acute distress. Some sufferers may be mentally confused and fear impending death. Initially these attacks tend to occur unexpectedly but, if recurrent, they often become associated with certain places such as a con?ned space (lift) or among crowds. Symptoms include a feeling of breathing diffculties, including overbreathing, PALPITATION, dizziness, sweating, faintness and pains in the chest. Attacks are usually short (a few minutes) but not often associated with physical illness, although victims may have an anxiety disorder or PHOBIA. If troublesome or disabling, attacks can be treated symptomatically with short-term ANXIOLYTICS or on a long-term basis with BEHAVIOUR THERAPY.... panic attacks

Panicum Miliaceum

Linn.

Family: Poaceae.

Habitat: Cultivated mainly in Uttar Pradesh, Madhya Pradesh, Andhra Pradesh, Karnataka and Tamil Nadu.

English: Common Millet, Proso Millet, Hog Millet.

Ayurvedic: Chinaaka, Cheenaa.

Unani: Chinaa Ghaas, Faaluudaa.

Siddha/Tamil: Panivaragu.

Folk: Chenaa, Chi-Tibet.

Action: Seeds (grains)—demul- cent; used in diarrhoea. Plant— antigonorrhoeal.

The seedlings contain an alkaloid hordenine (beta-p-hydroxyphenethyl dimethylamine). Saponins afforded diosgenin and yamogenin isolated from the leaves.

The grains contain 10-18% of proteins which include prolamin, glutelin and smaller amounts of albumin and globulin. The protein has a biological value of 56% and a digestibility coefficient of 91% at 10% level of protein intake.

In Indian medicine, Chinaaka and Kangu (Setaria italica L. Beauv.) are synonyms.

(0.015%). The capsules contain morphine, thebine and narcotine and me- conic acid.

Other species, commonly grown in Indian gardens, are P. nudicaule Linn. (Iceland Poppy) and P. orientale (Oriental Poppy). P. nudicaule plants with yellow flowers are more cyanogenetic than those with red or white flowers. P. orientate contains 0.16% alkaloids, which include the- baine, isothebaine, protopine, glauci- dine and oripavine. Isothebaine stimulates and later depresses the central nervous system.... panicum miliaceum

Panphila

(Greek) Daughter who is loved by all

Panphilah, Panphilla, Panfila, Panfilah, Panfilla... panphila

Panthea

(Greek) Of the gods and goddesses Pantheah, Panthia, Panthiya, Pantheia, Panthya... panthea

Panther

(American) Resembling the wild animal

Panthar, Panthur, Panthir, Panthyr... panther

Pantxike

(Latin) A woman who is free Pantxikey, Pantxikye, Pantxeke, Pantxyke... pantxike

Panya

(Slavic / Latin) An enthroned woman; crowned with laurel / a small child; mousy Panyah, Panyin, Panyen... panya

Papaveretum

The hydrochlorides of ALKALOIDS of OPIUM. Papaveretum relaxes smooth MUSCLE and has the pain-relieving and narcotic effects of MORPHINE, but fewer side-effects. It is largely used to prepare patients for ANAESTHESIA.... papaveretum

Papaver Somniferum

Linn.

Family: Papaveraceae.

Habitat: Kashmir and throughout the plains of North India; cultivated in gardens.

English: Corn Poppy, Red Poppy.

Ayurvedic: Rakta Posta.

Siddha/Tamil: Sivappu, Kasakasa.

Folk: Laal Posta, Laal Kaskas.

Action: Latex from capsules— narcotic. Petal—expectorant, antitussive, sudorific. Used for diseases of the respiratory tract, for disturbed sleep and as a sedative for the relief of pain. (Included among unapproved herbs by German Commission E.)

The petals contain cyanidine derivatives. An alkaloid rhoeadine is present in leaves and flowers (0.031%), unripe capsules (0.035%) and in roots

Family: Papaveraceae.

Habitat: Native to Asia; now grown in Uttar Pradesh, Punjab, Rajasthan and Madhya Pradesh.

English: Opium Poppy.

Ayurvedic: Ahiphena, Aaphuuka. Post-daanaa (seed).

Unani: Afyum. Tukhm-e- khashkhaash (seed).

Siddha/Tamil: Kasakasa (seeds).

Action: Opium is obsolete as a drug. Narcotic, sedative, hypnotic, analgesic, sudorific, anodyne, antispasmodic. Crushed poppyheads were in use as a topical poultice for crippling pain in terminal diseases. Poppy seed—nutritive, demulcent, emollient, spasmolytic, devoid of narcotic properties. Specific against obstinate constipation, also used in catarrh of the bladder. Poppy seed oil is also free from narcotic properties. Used against diarrhoea, dysentery and scalds.

Opium contains isoquinoline alkaloids; the major one is morphine with narcotine, codeine, papaverine and thebaine. Poppy seeds, used in Indian medicine, do not contain alkaloids. The seeds contain thiamine 420, riboflavin 49, folic acid 30, pantothenic acid 2667 and niacin 1877 mcg/100 g. The seed oil (from Turkey) contains gamma-tocopherol 220, alpha-toco- pherol 40 and beta-tocopherol 20 mcg/ 100 g. Some low-molecular proteins (15% of total protein) have been isolated, along with cysteine, glutamic acid and arginine. The seeds yield a fatty oil (45%) containing palmitic, stearic, oleic, linoleic and linolenic acids.

The extract of seeds showed highly significant antisecretory (antidiarr- hoeal activity) against E. coli entero- toxin-induced secretory responses in experimental animals.

The triglycerides isolated from seeds showed anti-tumour activity against Ehrlichs ascites in mice.

The aqueous extract of seeds showed marked hypoglycaemic activity when administered to glucose-loaded and al- loxan diabetic rats.

The seeds were found to increase the activity of carcinogen detoxifying enzyme, glutathione-S-transferase by more than 78% in the stomach, liver and oesophagus in mice.

Following Papaver sp. are found in India:

P. argemone Linn. (indigenous to the Mediterranean region; commonly grown in gardens in India) contains 0.15% of alkaloids including rhoeadine, protopine, and anthocyanins. Petals are sudorific.

P dubium Linn. (North-western Himalaya form Kashmir to Garhwal; as a winter weed in North Indian plains) contains rhoeagenine as the principal alkaloid, besides rhoeadine, protopine. Petals contain cyanidin B and pelargonidin C. Petals are sudorific.

P. hybridum Linn. (gardens of Punjab and Uttar Pradesh) is diaphoretic (petals). Plant latex contains alkaloids including berberine, coptisine, pahybrine, papaverrubines A, B, D and E and sanguinarine. Plant also gave glaucine and glucamine.

P. nudicaule Linn. (Gulmarg, Kashmir, at altitudes of 3,300-3,600 m), known as Iceland Poppy, gave alkaloids including papaverrubines B and D; leave gave cyanogenic glycosides including dhurrin and triglochinin. The flower and fruit are mild diaphoretic.

P. orientale Linn. (indigenous to Mediterranean region; grown in Indian gardens), known as Oriental Poppy, contains 0.16% of alkaloids including thebaine, isothebane, protopine, glaucidine and oripavine. Latex from poppy capsule is narcotic.... papaver somniferum

Papaya Or Pawpaw

Carica papaya

Description: The papaya is a small tree 1.8 to 6 meters tall, with a soft, hollow trunk. When cut, the entire plant exudes a milky juice. The trunk is rough and the leaves are crowded at the trunk’s apex. The fruit grows directly from the trunk, among and below the leaves. The fruit is green before ripening. When ripe, it turns yellow or remains greenish with a squashlike appearance.

Habitat and Distribution: Papaya is found in rain forests and semievergreen seasonal forests in tropical regions and in some temperate regions as well. Look for it in moist areas near clearings and former habitations. It is also found in open, sunny places in uninhabited jungle areas.

Edible Parts: The ripe fruit is high in vitamin C. Eat it raw or cock it like squash. Place green fruit in the sun to make it ripen quickly. Cook the young papaya leaves, flowers, and stems carefully, changing the water as for taro.

CAUTION

Be careful not to get the milky sap from the unripe fruit into your eyes. It will cause intense pain and temporary--sometimes even permanent--blindness.

Other Uses: Use the milky juice of the unripe fruit to tenderize tough meat. Rub the juice on the meat.... papaya or pawpaw

Papillae

Small raised bumps or nipples on a tissue surface. Lingual papillae are taste buds.... papillae

Papova Viruses

These include the human papilloma viruses (HPV), of which nearly a hundred strains have been identi?ed. HPV cause verrucae (see WARTS) on skin and, less often, on the mucous membranes of mouth, larynx, genitalia and the cervix. Some strains may predispose to eventual cancer.... papova viruses

Paprika

(English) Resembling the spice; a lively woman

Paprikah, Papryka, Papreka, Papricka, Paprycka, Paprecka, Papreeka, Papreaka, Papreika, Paprieka... paprika

Papyrus

Protection ... papyrus

Para-amino Salicylic Acid

One of the early antituberculous (see TUBERCULOSIS) antibiotics. It tended to cause DYSPEPSIA and has been replaced by newer antituberculous drugs with fewer side-effects. The ?rst-line drugs for tuberculosis are now rifampicin, isoniazid, and ethambutol.... para-amino salicylic acid

Paraaha

(Russian) Born on Good Friday Paraha, Parashy, Parashie, Parashi, Parashey, Parashee, Parashea... paraaha

Paracetamol Poisoning

Paracetamol is one of the safest drugs when taken in the correct dosage, but overdose may occur inadvertently or deliberately. Initially there may be no symptoms or there may be nausea, vomiting, abdominal pain and pallor. Then, 16–24 hours after ingestion, liver damage becomes evident and by 72–120 hours the patient may have JAUNDICE, COAGULATION abnormalities, hepatic failure (see LIVER, DISEASES OF), renal failure (see KIDNEYS, DISEASES OF), ENCEPHALOPATHY and COMA. Treatment involves the administration of antidotes such as METHIONINE (within 8 hours) orally or intravenous ACETYLCYSTEINE.

An overdose of paracetamol is a common choice of those attempting to commit suicide. Since the government restricted the number of paracetamol tablets an individual may purchase over the counter, the incidence of people taking the drug in overdose with the intention of taking their lives has fallen sharply.... paracetamol poisoning

Paradise

(English) From the perfect place Paradice, Paradyse, Paradyce... paradise

Paraffin

The general name used to designate a series of saturated hydrocarbon compounds derived from petroleum. Liquid para?n is used in the treatment of CONSTIPATION. Externally, the hard and soft para?ns are used in various consistencies, being very useful as OINTMENTS and lubricants.... paraffin

Paragraphia

Misplacement of words, or of letters in words, or wrong spelling, or use of wrong words in writing as a result of a lesion in the speech region of the BRAIN.... paragraphia

Parainfluenza Viruses

These are included in the paramyxoviruses (see MYXOVIRUSES) and divided into four types, all of which cause infection of the respiratory system (see RESPIRATION). Infection with type 3 begins in May, reaches a maximum in July or August and returns to base-line level in October. Types 1 and 2 are predominantly winter viruses. Children are commonly affected and the manifestations include CROUP, fever, and a rash.... parainfluenza viruses

Paralysis Agitans

See PARKINSONISM.... paralysis agitans

Paralytic Shellfish Poisoning

Poisoning by saxitoxin, a toxin present in some shellfish, usually in tropical or subtropical seas. Symptoms of respiratory arrest, or brain involvement occur in some 8% of cases, resulting in death. Saxitoxin is related to tetrodotoxin.... paralytic shellfish poisoning

Parametric Statistics

Statistical techniques designed for use when data have certain characteristics.... parametric statistics

Paranasal Sinus

Sited within some of the bones of the SKULL, these are spaces ?lled with air and lined by MUCOUS MEMBRANE. The sinuses comprise frontal and maxillary (a pair of each), ethmoidal (a group of small spaces), and two sphenoid sinuses. They drain into the nasal cavities (see NOSE). When a person has an upper respiratory infection, the sinuses sometimes become infected: this causes pain, purulent discharge from the nose and obstruction of the nasal passages (see SINUSITIS). Generally all that is required is a decongestant and antibiotic but, occasionally, infection may spread to produce a cerebral abscess or cerebral venous sinus thrombosis (see BRAIN, DISEASES OF).... paranasal sinus

Paras

(Indian) A woman against whom others are measured... paras

Parasitaemia

Parasites circulating in the blood stream.... parasitaemia

Parasite Density

The number of malaria parasites in a specified volume of blood.... parasite density

Parasitism

A type of association where one organism depends for metabolism on the other.... parasitism

Parasympathetic

A division of the autonomic (involuntary) nervous system that controls normal digestive, reproductive, cardiopulmonary, and vascular functions and stimulates most secretions. This subsystem works as a direct antagonist to the sympathetic division, and organ functions balance between them.... parasympathetic

Paratenic Host

An intermediate host which becomes infected by consuming another intermediate host and in which the parasite does not develop any further than in the first intermediate host. Also called a “transport host”.... paratenic host

Parcae

(Latin) In mythology, a name that refers to the Fates

Parca, Parcia, Parcee, Parsae, Parsee, Parsia, Parcea... parcae

Parental

Administration, other than orally, of a substance e.g. intramuscular or intravenous.... parental

Paresthesia

Numbness, prickly sensations without point specificity, or abnormal hypersensitivities, all local to one part of the body, and without an obvious cause. Your foot falling asleep is paresthetic, but not paresthesia...the cause is you sat funny.... paresthesia

Parathyroid

The grouping of four small glands, about 5 mm in diameter, which lie to the side of and behind the THYROID GLAND. These glands regulate the metabolism of calcium and of phosphorus. If for any reason there is a de?ciency of the secretion of the parathyroid glands, the amount of calcium in the blood falls too low and the amount of phosphorus increases. The result is the condition known as TETANY characterised by restlessness and muscle spasms – sometimes severe. The condition is checked by the injection of calcium gluconate, which causes an increase in the amount of calcium in the blood.

The most common cause of this condition (hypoparathyroidism) is accidental injury to or removal of the glands during the operation of thyroidectomy for the treatment of Graves’ disease (see THYROID GLAND, DISEASES OF – Thyrotoxicosis). If there is over-production of the parathyroids, there will be an increase of calcium in the blood: this extra calcium is drawn from the bones, causing cysts to form with resulting bone fragility. This cystic disease of bone is known as OSTEITIS FIBROSA CYSTICA. Tumours of the parathyroid glands result in this overactivity of the parathyroid hormone, and the resulting increase in the amount of calcium in the blood leads to the formation of stones in the kidneys. The only available treatment is surgical removal of the tumour. Increased activity of the parathyroid glands, or hyperparathyroidism, may cause stones in the kidneys. (See KIDNEYS, DISEASES OF.)... parathyroid

Parathyroids

These are several minute glandular masses embedded in the lower edge of the thyroid gland. They produce Parathyroid Hormone (PTH), part of the calcium-phosphorus control system. Calcium levels in the blood MUST be within a narrow band of safety. If free calcium drops too low, PTH acts on the kidneys and blocks calcium loss in urine, amplifies calcium absorption into the portal blood (from food and from submucosal storage) and stimulates release of calcium from bone storage. When levels are back up, the hormone backs off. Oddly enough, the thyroid gland secretes its virtual antagonist, calcitonin, which, when calcium levels are too high, stimulates the urine excretion, bone retention and digestive resistance to calcium, and when the blood levels drop, recedes. The body finds calcium levels to be so critical that it has in place TWO separate, mutually antagonistic negative feedback systems,,,like a binary star system. (Be thankful I didn’t bring in the calcium maintenance of minerocortical steroid hormones or vasopressin)... parathyroids

Parenchymal

These are cells in a tissue or tissues in an organ that are concerned with function. These are the characteristic cells or tissues that do the actual stuff. The importance to us is that parenchymal tissues expend much vital energy in their functions and are less tolerant of a degraded environment than the structural mesenchyme. A congested and impaired organ like the liver of a heavy drinker has so much regular dysfunction that eventually the more tolerant and metabolically less particular mesenchymal cells become more common, and the distressed, overworked, and metabolically compromised parenchymal cells become a minority. The structural cells can multiply with ease in a poor environment, the more delicate functional cells cannot-and you end up with the type of cirrhosis sometimes termed mesenchymal invasion disease. The point of this is that the sooner you return an organ or tissue back to the healed state, the more likely you are to have a healthy balance between the structural and functional.... parenchymal

Parenteral Nutrition

In severely ill patients – especially those who have had major surgery or those with SEPSIS, burns, acute pancreatitis (see PANCREAS, DISORDERS OF) and renal failure – the body’s reserves of protein become exhausted. This results in weight loss; reduction in muscle mass; a fall in the serum albumin (see ALBUMINS) and LYMPHOCYTE count; and an impairment of cellular IMMUNITY. Severely ill patients are unable to take adequate food by mouth to repair the body protein loss so that enteral or parenteral nutrition is required. Enteral feeding is through the gastrointestinal tract with the aid of a nasogastric tube; parenteral nutrition involves the provision of carbohydrate, fat and proteins by intravenous administration.

The preferred route for the infusion of hyperosmolar solutions is via a central venous catheter (see CATHETERS). If parenteral nutrition is required for more than two weeks, it is advisable to use a long-term type of catheter such as the Broviac, Hickman or extra-corporeal type, which is made of silastic material and is inserted via a long subcutaneous tunnel; this not only helps to ?x the catheter but also minimises the risk of ascending infection.

Dextrose is considered the best source of carbohydrate and may be used as a 20 per cent or 50 per cent solution. AMINO ACIDS should be in the laevo form and should contain the correct proportion of essential (indispensable) and non-essential amino acids. Preparations are available with or without electrolytes and with or without fat emulsions.

The main hazards of intravenous feeding are blood-borne infections made possible by continued direct access to the circulation, and biochemical abnormalities related to the composition of the solutions infused. The continuous use of hypertonic solutions of glucose can cause HYPERGLYCAEMIA and glycosuria and the resultant POLYURIA may lead to dehydration. Treatment with INSULIN is needed when hyper-osmolality occurs, and in addition the water and sodium de?cits will require to be corrected.... parenteral nutrition

Paresthesiae

Tingling and burning in the skin frequently described as “pins and needles”. It is caused by irritation of cutaneous nerves by a variety of causes including trauma and envenomation.... paresthesiae

Pari

(Persian) A fairylike young girl Parie, Pary, Parey, Paree, Parisa, Parihan, Parehan, Paryhan, Parea... pari

Paris

(English) Woman of the city in France Pariss, Parisse, Parys, Paryss, Parysse... paris

Paris Polyphylla

Sm.

Family: Liliaceae.

Habitat: Temperate Himalayas from Simla to Bhutan and in Lushai and Aka Hills. Haimavati, Shveta-

Action: Plant—sedative, analgesic, haemostatic, anthelmintic.

The rhizome contains a glucoside, alpha-paristyphnin, which exhibited a depressant action on carotid pressure, myocardium, and respiratory movements experimentally. It produced vasoconstriction in kidney, but vasodilation in the spleen and limbs, and stimulated isolated intestines.... paris polyphylla

Park

(Chinese) Of the cypress tree Parke, Parka... park

Parker

(English) The keeper of the park... parker

Parley

(English) One who negotiates Parly, Parli, Parlie, Parlee, Parleigh, Parlea... parley

Parmelia Perlata

(Huds.) Ach.

Family: Parmeliaceae.

Habitat: Cultivated in Kashmir hills and the Himalayas.

Ayurvedic: Shaileya, Shaileya- ka, Shilaapushpa, Shilaadaaru, Shailaka, Shilodbhava, Shaila, Shailpushpa. Kaalaanu-saarthaka, Bhuri-charilla, Sthavira, Vrddha, Shitashiva.

Unani: Charelaa.

Action: Astringent, resolvent, diuretic. Used externally for pain in renal and lumbar regions. Also used as an ingredient in cosmetic preparations.

The lichen contains lecanoric acid and atranorin.

Several lichen species contain abundant quantities of usnic acid which exhibits antimicrobial and antifungal activity and is immunologically active in contact dermatitis.

The Ayurvedic Pharmacopoeia of India recommends the thallus in dysuria.

Dosage: Whole thallus—1-3 g powder. (API, Vol. III.)... parmelia perlata

Parmida

(Persian) Daughter born to royalty Parmidah, Parmyda, Parmeda, Parmeeda, Parmita, Parmyta, Parmeta, Parmeeta, Parmeada, Parmeata... parmida

Parminder

(Hindi) An attractive lady Parmender, Parmynder, Parmindar, Parmendar, Parmyndar... parminder

Parnika

(Indian) A successful woman Parnikah, Parnikka, Parnicka, Parnyka, Parneka, Parnita, Parneta, Parnyta... parnika

Parosela

Hunting... parosela

Parotid

A pair of salivary glands tucked into the notch in front of each ear and emptying through parotid ducts by each upper 2nd molar. Although the fluid has some of the thick viscous lubricant nature of saliva from the glands in the floor of the mouth, the parotids secrete high levels of ptyelin and amylase (starch-digesting enzymes) lysozymes (antimicrobial enzymes) and a group of proteins loosely called parotin that stimulate epithelial and nerve cell growth...a lot more here than just spit.... parotid

Parous Rate

The proportion of female mosquitoes that have laid eggs at least once. Use for age-grading a mosquito population.... parous rate

Parrish

(Latin) Woman of the church Parish, Parrishe, Parishe, Parrysh, Parysh, Paryshe... parrish

Parry

(Welsh) Daughter of Harry Parri, Parrie, Parrey, Parree, Parrea... parry

Parsley Piert

Alchemilla arvensis. N.O. Rosaceae.

Synonym: Parsley Breakstone.

Habitat: Hedgerows, in better soils.

Features ? Up to six inches in height, the whole plant rather hairy. Leaves small, trifid higher up the stem, palmate lower down. Axillary tufts of small, greenish flowers.

Part used ? Herb.

Action: Diuretic, demulcent.

A widely-used diuretic acting directly on the parts. The 1 ounce to 1 pint infusion may be given in teacupful doses thrice daily in all kidney and bladder irregularities.... parsley piert

Parson

(English) A member of the clergy Parsan, Parsun, Parsin, Parsyn... parson

Parthenia

(Greek) One who is chaste; a virgin

Parthenie, Parthenea, Partheniya, Partheniah, Partheni, Partheny, Partheney, Parthenee, Parthenea... parthenia

Parthenium Hysterophorus

Linn.

Family: Compositae; Asteraceae.

Habitat: Tropical and subtropical countries of the world.

English: Congress Grass.

Folk: Pichhi, Machhipatri.

Action: Anti-amoebic, antidysen- teric, febrifuge, analgesic, emmena- gogue.

The grass was introduced into India during 1950 s (it first appeared in Pune).

The grass exhibits in vitro anti- amoebic activity against axenic and polygenic cultures of Entamoeba his- tolytica, comparable to the standard drug for amoebiasis, Metronidazole.

Parthenin and some of its derivatives exhibited significant antimalarial activity against a multi drug-resistant strain of Plasmodium falciparum.

The main toxic constituent of the grass responsible for causing dermatitis and other forms of allergy are parthenin and coronopilin. Parthenin in present up to 8% in the capitulum and 5% in the leaves.... parthenium hysterophorus

Parthenocissus Himalayana

(Royle) Planch.

Synonym: Vitis himalayana Brandis.

Family: Vitaceae.

Habitat: Throughout the Himalayas.

Folk: Kandur (Jaunsar), Philunaa (Garhwal) Laderi (Kumaon).

Action: Bark and twigs—astringent and expectorant.... parthenocissus himalayana

Parthenope

(Greek) In mythology, a siren... parthenope

Participant Observation

A qualitative data collection technique in which the researcher participates in activities in a setting to observe and record (or simply study) actors’ behaviour. Not all participant observation requires the researcher to conceal his/her identity (thus participate as a member of the group).... participant observation

Participatory Research

A process in which the researcher facilitates analysis by a range of stakeholder groups of the themes being investigated.... participatory research

Partiurient

Inducing the contractions of labour at childbirth... partiurient

Partnership For Health Promotion

A voluntary agreement between two or more partners to work cooperatively towards a set of shared health outcomes.... partnership for health promotion

Parvaneh

(Persian) Resembling a butterfly Parveneh, Parvane, Parvene... parvaneh

Parvani

(Indian) Born during a full moon Parvanie, Parvany, Parvaney, Parvanee, Parvanea... parvani

Parvati

(Hindi) Daughter of the mountain; in Hinduism, a name for the wife of Shiva Parvatie, Parvaty, Parvatey, Parvatee, Pauravi, Parvatea, Pauravie, Pauravy, Pauravee, Pauravea... parvati

Parvin

(Persian) Cluster of stars in the constellation Taurus

Parvine, Parveen, Parveene, Parvyn, Parvynne, Parvean, Parveane... parvin

Parvoviruses

(from parvus, Latin for small) is a group of viruses responsible for outbreaks of WINTER VOMITING DISEASE. One strain is the cause of ERYTHEMA infectiosum (slapped-cheek syndrome).... parvoviruses

Pascale

(French) Feminine form of Pascal; born on Easter

Pascaleh, Pascala, Pascaline, Pasclina, Pascalla, Pascalia, Pascha... pascale

Pascasia

(French) Born on Easter Paschasia, Pasua... pascasia

Paschel

(African) A spiritual woman Paschell, Paschele, Paschelle, Paschela, Paschella... paschel

Pash

(French) A clever woman Pashe, Pasch, Pasche... pash

Pasha

(Greek) Woman of the sea Pashah, Passha, Passhah... pasha

Pasiphae

(Greek) In mythology, the wife of Minos and mother of the Minotaur Pasiphay, Pasiphai... pasiphae

Pasithea

(Greek) In mythology, the oldest of the Graces

Pasitheah, Pasithia, Pasithiya, Pasithee, Pasithi, Pasithie... pasithea

Paspalum Scrobiculatum

Linn.

Family: Gramineae; Poaceae.

Habitat: Cultivated throughout India.

English: Kodo millet. Ayurvedic: Kodrava, Korduusha. Siddha/Tamil: Varagu. Folk: Kodo.

Action: Plant—used as a CNS drug for treating schizophrenia and psychoses.

The plant contains hentriacontanol, hentriacontanone and sitosterol. The grains have often been reported to cause poisoning in men and animals when used as a food; non-poisonous types have been reported from Tamil Nadu.... paspalum scrobiculatum

Passiflora Edulis

Sims.

Family: Passifloraceae.

Habitat: Native of Brazil; cultivated in Tamil Nadu, Kerala and Andhra Pradesh, in North India in Punjab and Himachal Pradesh.

English: Purple Granadilla, Passion Fruit.

Action: Juice from purple fruit— a good source of ascorbic acid (contains up to 75 mg/100 g), carotene and sugars.

The juice from the yellow variety (equated with Passiflora edulis f. flavi- carpa) contains lesser amounts of ascorbic acid and sugars.

The purple Passion fruit contains the C-glucoside, beta-ionyl-beta-D- glucopyranoside. A protease inhibitor (PEPI) has been isolated from the juice. PEPI inhibited trypsin and chy- motrypsin activities, but did not inhibit papain activity. The esters and terpenoids form the major part of fruit components. The terpenoids include a number of monoterpenes (including hydroxylated linalool derivatives), and monoterpene glycosides. Norter- penoid aglycones have also been found.

The yellow Passion fruit contains sulfur-containing volatiles, acetates, butanoates and hexanoates of 3-mer- captohexanol. The leaves contain C- glycosylflavonoids.... passiflora edulis

Passiflora Foetida

Linn.

Family: Passifloraceae.

Habitat: Native to America; found willd in Uttar Pradesh, Karnataka and Tamil Nadu.

English: Stinking Passion Flower.

Siddha/Tamil: Siru Ponaikalli.

Action: Leaves and roots—em- menagogue, antihysteric. Fruits— emetic. A decoction is used for biliousness and asthma (for expelling bile and cough).

The plant contains C-glycosides of apigenin and luteolin. Apigenin-8- C-glucoside has been detected in the plant.... passiflora foetida

Passiflora Laurifolia

Linn.

Family: Passifloraceae.

Habitat: Native of tropical America; grown in Indian gardens.

English: Water-lemon, Jamaica Honey Suckle.

Action: Leaves—anthelmintic. Seeds—hypnodil. Fruit—edible. Plant—poisonous (the foliage produces hydrocyanic acid).

The fruit pulp contains pantothenic acid (1.55 mg/100 g); leaves contain 387 mg/100 g vitamin C.... passiflora laurifolia

Passiflora Quadrangularis

Linn.

Family: Passifloraceae.

Habitat: Native of tropical America; grown in Indian gardens.

English: Giant Granadilla.

Action: Fruit—edible; contains 64 mg/100 g ascorbic acid; narcotic when eaten in excess. Leaves, the peel and seeds of green fruit, and roots—cyanogenetic. Roots— poisonous.

The root contains an alkaloid Passiflora which is identical with harman from Passiflora incarnata.... passiflora quadrangularis

Passion

(American) A sensual woman Pashon, Pashun, Pasyun, Passyun... passion

Passion Flower

Peace, Sleep, Friendship ... passion flower

Passive Intervention

Health promotion and disease prevention initiatives which do not require the direct involvement of the individual (e.g. fluoridation programmes) are termed “passive”.... passive intervention

Passiflora Incarnata

Linn.

Family: Passifloraceae.

Habitat: Native of South-east America; grown in Indian gardens.

English: Wild Passion Flower, Maypop.

Action: Flowering and fruiting dried herb—mild sedative, hypnotic, tranquilizer, hypotensive, vasodilator, antispasmodic, anodyne, anti-inflammatory,

Key application: In nervous restlessness, irritability and difficulty in falling asleep. (German Commission E, ESCOP, The British Herbal Compendium, The British Herbal Pharmacopoeia, WHO.) The British Herbal Compendium also indicated it in neuralgia, dysmenorrhoea, and nervous tachycardia.

The herb contains flavonoids (up to 2.5%), in particular C-glycosylflavones; cyanogenic glycoside, gynocardine.

The alkaloid harman has been isolated, but the presence of harmine, har- maline, harmol and harmalol has been disputed. The alkaloid and flavonoids are reported to have sedative activity in animals. Apigenin exhibits antispasmodic and anti-inflammatory activity.

Passion Flower was formerly approved as an OTC sedative in the USA, but it was taken off the market in 1978 because safety and effectiveness had not been proven. An animal study in 1977 suggested that apigenin binds to central benzodi-zepine receptors (possibly causing anxiolytic effects). (Natural Medicines Comprehensive Database, 2007.)

The drug is used in homoeopathic medicine for epilepsy.

The herb exhibits a motility-inhi- biting effect in animal experiments.

Passion Flower, used as an adjunct to clonidine, was superior to clonidine for mental symptoms of opiate withdrawal. (Sharon M. Herr.)... passiflora incarnata

Passionfruit Tea

Passionfruit Tea is known for its astringent and slightly sweet and fruity taste. It is typically made out of a black tea base that has been infused with the essence and flavor of passionfruit. The passionfruit (passiflora edulis) is native to northern and central South America. It can be recognized by its round to oval shape, having either yellow or dark purple color. It has a juicy interior, full with a lot of seeds. Passionfruit Tea is rich in antioxidants, amino acids, vitamins (B, C and E) and minerals (magnesium and potassium). How To Make Passionfruit Tea To brew Passionfruit Tea, you will have to place 1 teaspoon of loose-leaf tea or 1 passionfruit teabag in a cup of boiled water. Let the mix steep for about 3-4 minutes and then, pour the tea into your cup using a strainer to catch the leaves (if you are making tea out of leaves). You can sweeten the tea by adding honey or sugar. The best thing about this tea is that it can be drank either hot or cold. Passionfruit Tea Benefits
  • Lowers the risk of developing cardiovascular diseases.
  • Provides relaxation.
  • Improves digestion.
  • Due to its antioxidant content, Passionfruit Tea may help lowering the risk of developing tumors and cancer.
  • Strengthens the immune system.
  • Fights skin and tissue damage.
Passionfruit Tea Side Effects Passionfruit Tea has not presented any severe side effects. However, it does have some possible side effects that should be taken into consideration when drinking any type of tea.
  • Pregnant and breastfeeding women should avoid drinking Passionfruit Tea.
  • Passionfruit Tea may interact with the effects of some medications, so consult your doctor before drinking passionfruit tea.
  • People with blood sugar problems should also avoid drinking Passionfruit Tea.
Passionfruit Tea makes an excellent fruit tea option. It can be drank either hot or cold, so it is ideal for both winter and summer! Just make sure you enjoy all its benefits!... passionfruit tea

Pastes

See OINTMENTS.... pastes

Pastora

(Spanish) A shepherdess Pastore, Pastoria, Pastorea, Pastoriya... pastora

Patchouly

Money, Fertility, Lust... patchouly

Patellar Reflex

See REFLEX ACTION.... patellar reflex

Patellar Tendinitis

Also known as jumper’s knee. In?ammation of the tendon of the extensor muscle of the thigh, in which the PATELLA or knee-cap is secured. Usually the result of injury or excessive use or stress – for example, in athletic training – symptoms include pain, tenderness and sometimes restricted movement of the parent muscle. Treatment may include NON-STEROIDAL ANTIINFLAMMATORY DRUGS (NSAIDS), ULTRASOUND treatment and PHYSIOTHERAPY, and, if persistent, injection of a corticosteroid drug (see CORTICOSTEROIDS) around the tendon.... patellar tendinitis

Pasteurisation

A method of sterilising milk (see also MILK – Preparation of milk). In many parts of the world, pasteurisation has done away with milk-borne infections, of which the most serious is bovine TUBERCULOSIS, affecting the glands, bones and joints of children. Other infections conveyed by milk are SCARLET FEVER, DIPHTHERIA, ENTERIC FEVER (typhoid and paratyphoid), undulant fever (BRUCELLOSIS), and food poisoning (e.g. from CAMPYLOBACTER, or the toxins of the STAPHYLOCOCCUS).

High-temperature short-time (HTST) pasteurisation consists of heating the milk at a temperature not less than 71·7 °C (161 °F) for at least 15 seconds, followed by immediate cooling to a temperature of not more than 10 °C (50 °F).

Low-temperature pasteurisation, or ‘holder’ process, consists in maintaining the milk for at least half an hour at a temperature between 63 and 65 °C (145–150 °F), followed by immediate cooling to a temperature of not more that 10 °C (50 °F). This has the e?ect of considerably reducing the number of bacteria contained in the milk, and of preventing the diseases conveyed by milk as referred to above.... pasteurisation

Pastinaca Sativa

Linn.

Synonym: Peucedanum sativum Benth. & Hook. f.

Family: Umbelliferae; Apiaceae.

Habitat: Native to Europe; grows in cool climate in India. (Hollow Crown, Student and Large Guernsey are Indian horticultural varieties.)

English: Parsnip.

Action: Above ground parts— diuretic, carminative (eaten as a vegetable and salad), used for kidney disorders. Root—used for kidney disorders, fever and as a diuretic and analgesic.

The parsnip is a rich source of coumarins (1.7% dry weight). The coumarin fraction of the fruit extract inhibits growth of cancer cells (HeLa- S3)cultured in the dark. The fruit contains small amounts of photoactive furocoumarins which are phototoxic. (Severe dermatitis results after contact with the furocoumarin in the presence of light.) The fruit contains xantho- toxin (0.1%), imperatorin (0.17%) and bergapten (0.38%). Coumarin, pasti- nacin, isolated from the fruit, showed spasmolytic action.... pastinaca sativa

Pastinaca Secacul

Linn. Family: Umbelliferae; Apiaceae.

Habitat: Native to Europe. English: Wild Parsnip. Unani: Shaqaaq-ul-Misri.

Action: Root—galactagogue, aphrodisiac, spermatogenetic. An important ingredient of Unani compounds for oligospermia, low sexual drive and debility. Shaqaaq-ul-Misri has also been equated with Trachydium lehmanni Benth. In Kashmir, Eryngium caeru- leum Bieb (Umbelliferae) and in Chak- rata, Polygonatum verticillatum All. (Liliaceae) are known as shaqaaqul (also Dudhaali). Polygonatum verticillatum rhizomes are used in Tibetan medicine for emaciation and senility. The dried rhizomes contain diosgenin.... pastinaca secacul

Paterekia

(Hawaiian) An upper-class woman

Paterekea, Pakelekia, Pakelekea... paterekia

Pathogenicity

Ability to cause disease.... pathogenicity

Pathologist

A doctor that specialises in the interpretation of changes in tissues.... pathologist

Pati

(African) One who fishes Patie, Paty, Patey, Patee, Patea... pati

Patience

(English) One who is patient; an enduring woman

Patiencia, Paciencia, Pacencia, Pacyncia, Pacincia, Pacienca... patience

Patient Assessment (resident)

Standardized tools to determine patient characteristics and abilities, what assistance they need and how they may be helped to improve or regain abilities. Patient assessment forms are completed using information gathered from medical records, interviews with the patient, other informants (e.g. family members) and direct observation.... patient assessment (resident)

Patient Care Planning

See “care plan”.... patient care planning

Pathogens

Micro-organisms that cause diseases, parasitising plants, animals and humans (see PARASITE). Some organisms are frequently PATHOGENIC, whereas others rarely cause disease. Opportunistic pathogens are those which rarely cause serious infection in healthy people but can do so in patients with weakened immune systems (immunocompromised – see IMMUNITY). Pathogens include BACTERIA, viruses (see VIRUS), prions (see PRION), fungi (see FUNGUS), PROTOZOA and metazoa (multicellular microorganisms called HELMINTHS or worms). The pathogenicity of an organism is called its virulence, which is measured by the number of organisms required to cause disease. The 50 per cent of lethal dose (LD50) is the quantity of a particular pathogen needed to cause infection in half of the hosts invaded.... pathogens

Patient Choice

See ETHICS.... patient choice

Patient Consent

See ETHICS.... patient consent

Patient Empowerment

At a personal level, the engagement of individuals in decisions about their health and about the diagnosis, treatment and after-care of their illness, injuries and other disorders. At a public level, the engagement of all members of the public in the planning, provision and performance of their health-care services. Traditionally, at both personal and public levels, the patient has generally been regarded as naturally subordinate to the politicians and managers who plan and run the health-care system(s), and to health professionals and medical institutions who provide personal health care. The public and patients are increasingly unwilling to accept this traditional model and are asserting themselves, for example through patient help groups, complaints, litigation and local political action with the aim of securing changes in how health care is organised and a much greater say in their own care.... patient empowerment

Patient-centred Care

An approach to care that consciously adopts a patient’s perspective. This perspective can be characterized around dimensions such as respect for patients’ values, preferences and expressed needs; coordination and integration of care; information, communication and education; physical comfort, emotional support and alleviation of fear and anxiety; involvement of family and friends; or transition and continuity.... patient-centred care

Patient-controlled Analgesia

A technique whereby a patient can deliver an analgesic substance (see ANALGESICS) in amounts related to the extent of the PAIN that he or she is suffering. For example, to combat post-operative pain, some hospitals use devices which allow patients to give themselves small intravenous amounts of opiates when they are needed. Pain is more e?ectively controlled if it is not allowed to reach a high level, a situation which tends to happen when patients receive analgesics only on ward drug rounds or when they ask the nursing sta? for them.... patient-controlled analgesia

Patient-origin Study

A study, generally undertaken by an individual health programme or health planning agency to determine the geographic distribution of the residences of the patients served by one or more health programmes. Such studies help define catchment and medical trade areas and are useful in locating and planning the development of new services.... patient-origin study

Patients’ Rights

A set of rights, privileges, responsibilities and duties under which individuals seek and receive health care services. As patients’ rights are often not explicit, the composition of the set varies from country to country and over time.... patients’ rights

Patrice

(French) Form of Patricia, meaning “of noble descent”

Patriece, Patreece, Patreace, Patreice, Patryce... patrice

Patricia

(English) Feminine form of Patrick; of noble descent

Patrisha, Patrycia, Patrisia, Patsy, Patti, Patty, Patrizia, Pattie, Padraigin, Pat... patricia

Patrina

(American) Born into the nobility Patreena, Patriena, Patreina, Patryna, Patreana... patrina

Paul-bunnell Test

A test for MONONUCLEOSIS which is based upon the fact that patients with this disease develop ANTIBODIES which agglutinate sheep red blood cells.... paul-bunnell test

Paula

(English) Feminine form of Paul; a petite woman

Paulina, Pauline, Paulette, Paola, Pauleta, Pauletta, Pauli, Paulete, Pabla, Paulita, Pavlina, Pavleena, Pavlyna, Pavliena, Pavla... paula

Pausha

(Hindi) Resembling the moon Paushah... pausha

Pavan

(Indian / Latin) Resembling a fresh breeze / a dancer of the court Pavane, Pavania, Pavana, Pavanea... pavan

Pavati

(Native American) From the clear waters

Pavatie, Pavaty, Pavatey, Pavatee, Pavatea... pavati

Pavonia Zeylanica

Cav.

Family: Malvaceae.

Habitat: Throughout greater part of India.

Siddha/Tamil: Sithamutti, Mammat- ti, Peraamutti.

Action: Plant—purgative, an- thelmintic, febrifuge.

The stem gave a saponin, pavo- phylline, and a keto-ester, methyl 19- ketotetracosanoate.... pavonia zeylanica

Payton

(English) From the warrior’s village Paton, Paeton, Paiton, Payten, Paiten... payton

Peace

(American) A harmonious woman... peace

Peach

Love, Exorcism, Longevity, Fertility, Wishes... peach

Peaches

(American) As sweet as the fruit Peeches, Peachy, Peachey, Peachee, Peachea, Peachi, Peachie... peaches

Peak Biting Time

The period during which the biting cycle of a given mosquito species when the largest number of females take blood meals.... peak biting time

Paullinia Asiatica

Linn.

Synonym: Limonia oligandra Dalz. Toddalia aculeata Pers.

Family: Rutaceae.

Habitat: Found in Konkan and Maharashtra.

English: Lopez Root tree, Wild Orange tree, Forest Pepper.

Ayurvedic: Kaanchana, Dahana.

Siddha/Tamil: Kattu Milagu, Milagaranai.

Folk: Jangali Kaalimirchi, Limri (Maharashtra).

Action: Root bark—bitter, febrifuge, diaphoretic, antiperiodic. Infusion used in constitutional debility and convalescence after febrile and other exhausting diseases.

The root gave coumarins, including toddanol, todhanone, toddasin, pimpinellin, toddalolactone; alkaloids, including toddaline, toddalnine.... paullinia asiatica

Pavetta Indica

Linn.

P. tomentosa Roxb. ex

Family: Rubiaceae.

Habitat: Throughout greater part of India, ascending to an altitude of about 1,500 m in the Himalayas, also recorded from the Andamans.

English: White-Pavetta.

Ayurvedic: Papata, Kathachampaa.

Siddha/Tamil: Pavattai.

Folk: Paapadi (Maharashtra).

Action: Root—bitter and aperient. Prescribed in visceral obstructions, renal dropsy and ascites. Leaves— used for fomenting piles and for haemorrhoidal pains. The root bark contains d-mannitol.... pavetta indica

Pavonia Odorata

Willd.

Family: Malvaceae.

Habitat: North-West India, Bengal and Konkan.

English: Fragrant Sticky Mallow.

Ayurvedic: Vaalaka, Baalaka, Baala, Barhishtha, Hrivera, Ambu, Jala, Nira, Paya, Toya, Udichya, Vaari, Muurdhaja. Sugandhbaalaa (also equated with Valeriana Jatamansi). In the South, Celus vettiveroides is equated with Baalaka.

Siddha/Tamil: Peraamutti, Kastoori vendai.

Action: Plant—anti-inflammatory and spasmolytic. Used in rheumatic affections. Root—stomachic, astringent, demulcent. Used in dysentery, haemorrhages from intestines; ulcers and bleeding disorders.

The roots gave an essential oil containing isovaleric acid, isovaleralde- hyde, armomadendrene, pavonene, alpha-terpinene, azulene and pavo- nenol.

The plant exhibits antiparasitic activity against Entamoeba histolytica.... pavonia odorata

Peakalika

(Hawaiian) Filled with happiness... peakalika

Pear

Lust, Love... pear

Pearl

(Latin) A precious gem of the sea Pearla, Pearle, Pearlie, Pearly, Pearline, Pearlina, Pearli, Pearley, Pearlee, Pearlea, Pearleigh, Pearleah... pearl

Pebbles

(American) Resembling a small rock... pebbles

Pecan

Money, Employment... pecan

Pecola

(American) A brazen woman Pecolah, Pekola, Pekolah... pecola

Pectin

A polysaccharide substance allied to STARCH, contained in fruits and plants, and forming the basis of vegetable jelly. It has been used as a TRANSFUSION ?uid in place of blood in cases of haemorrhage and shock.... pectin

Pectoralgia

Pain in the chest... pectoralgia

Pedalium (pl. Pedalia)

The four flattened “corners” of cubozoan (box) jellyfish from which arise the tentacles - unlike other jellyfish where the tentacles arise from many, or any, areas of the bell.... pedalium (pl. pedalia)

Pedicel

The stem of a flower within a floral cluster.... pedicel

Pediculocide

A substance that kills Pediculosis capitis – head louse (see under PEDICULOSIS).... pediculocide

Pedalium Murex

Linn.

Family: Pedaliaceae.

Habitat: Throughout the plains of India.

English: Caltrops (bigger var.).

Ayurvedic: Brihatgokshura, Kshouraka, Trikantaka, Gokantaka, Swaadukantaka, Bhakshantaka.

Unani: Khaar-e-khasak Kalaan, Gokharu Kalaan.

Siddha/Tamil: Peru-neranji, Annai- neringi.

Action: Fruit—used for spermatorrhoea, nocturnal emissions, menstrual irregularities, puerperal diseases, genitourinary disorders, difficult micturition, chronic cystitis, renal calculus. Root— antibilious.

The stem and fruits contain flavo- noids pedalitin and its glucoside (ped- aliin), diometin, dinatin and its derivatives. The fruits contain nonaco- sane, tritriacontane, triacontanoic acid, sitosterol-beta-D-glucoside, rubusic acid, luteolin as major constituents. Leaves and fruits yield phenolic acids which include caffeic, protocatechuic, p-coumaric and ferulic acids. Flowers gave dinatin, quercetin and quercetin- 7-glucoside.

Aqueous extract of the fruit is reported to produce in vitro inhibitory effect on crystallization in urinary lithi- asis. The solubility of uric acid in aqueous extract is reported to be 45% more than in water alone.

The plant extracts exhibit diuretic activity.

Dosage: Fruit, root—3-5 g powder; 50-100 ml. decoction. (CCRAS.)... pedalium murex

Pedicularis Pectinata

Wall.

Family: Scrophulariaceae.

Habitat: The Himalayas from Kashmir eastwards at altitudes of 2,000-4,300 m, extending to Sikkim.

English: Lousewort.

Folk: Mishran, Michren (Punjab), Lugro-maarpro (Kashmir).

Action: Leaves—astringent, haemostatic, diuretic.

The herb is closely related to Eye- bright (Euphrasia officinalis Linn.) of the same family, found in the Temperate Himalayas from Kashmir to Ku- maon. Eyebright is astringent and bac- teriostatic.... pedicularis pectinata

Pediculus Humanus Var. Corporis

(body louse) di?ers from the head and crab louse in that it lives in clothing and only goes on to the body to feed. Infestation is found in vagabonds, armies in the ?eld, or prisoners in conditions where even minimal hygiene is impossible. The lice are found in the seams of clothing together with multiple eggs. Typically excoriation and pigmentation are seen on the back of the infested person. Replacement of clothing or autoclaving or hot ironing of the clothes is curative.... pediculus humanus var. corporis

Pedilanthus Tithymaloides

Poir.

Family: Euphorbiaceae.

Habitat: Native to West Indies; cultivated as an ornamental.

English: Slipper Plant, Bird-Cactus.

Folk: Vilaayati-sher (Maharashtra), Naagaphani, Naagadaman (Madhya Pradesh).

Action: Latex—used for warts, leucoderma, venereal diseases. Root—emetic (used in West Indies as Ipecacuanha).

An extract of the air-dried and powdered whole plant contains oc- tacosanol, cycloartenone, oxime and beta-sitosterol.

The latex from the stem contains the proteolytic enzyme, pedilanthain. It exhibited anti-inflammatory activity in carrageenan-induced rat paw oedema and was more effective than the control drug phenylbutazone. The enzyme also showed anthelmintic property.

The leaves contain n-hentriaconta- nol and dehydrodammaronol-A. The root gave azafrin.... pedilanthus tithymaloides

Pedzi

(American) A golden woman Pedzie, Pedzy, Pedzey, Pedzee, Pedzea... pedzi

Peer Counselling

Provision of support and advice to older persons by non­professional persons who are or have been in similar circumstances.... peer counselling

Peer Review (in Research)

The process by which manuscripts submitted to a publisher or research applications are evaluated by experts in appropriate fields (usually anonymous to the authors) to ensure quality.... peer review (in research)

Peggy

(English) Form of Margaret, meaning “resembling a pearl / the child of light” Peggi, Peggie, Pegeen, Peg, Peigi, Peggee, Peggea, Peggey... peggy

Pegma

(Greek) Filled with happiness Pegmah, Pegmia, Pegmiah, Pegmea, Pegmeah... pegma

Peke

(Hawaiian) A giving woman... peke

Pela

(Polish) Woman of the sea Pelah, Pella, Pellah... pela

Pelagia

(Greek) Feminine form of Pelagius; woman of the sea

Pelagiah, Pelagea, Pelagiya, Pelageah, Pelagla, Pelaglah, Pelagie, Pelagy, Pelagi, Pelagey, Pelagee, Pelagias, Pelaga... pelagia

Pelagia Noctiluca

A very common jellyfish known as the little mauve stinger, which has occurred in severe `swarms’ in the Mediterranean Sea. The sting causes moderate skin pain, but may also cause systemic symptoms such as cough, sneezing, painful breathing and nasal catarrh. It has not caused death, but one severe case of potentially-fatal anaphylaxis occurred in the wife of the then Greek Prime Minister.... pelagia noctiluca

Pelagic

The open sea (ocean) habitat of some animals.... pelagic

Peganum Harmala

Linn.

Family: Zygophyllaceae.

Habitat: Throughout Northern and Northwestern India, and in drier regions of Deccan.

English: Wild Rue; Foreign Henna, Syrian Rue.

Ayurvedic: Haramal, Isband.

Siddha/Tamil: Simaiyaravandi, Simaiyalavinai.

Action: Plant—emmenagogue, abortifacient. Seeds—narcotic, hypnotic, antispasmodic, anodyne and emetic; used in asthma, hiccough, colic, neuralgia, hysteria, dysmenorrhoea; used as abortifa- cient (properties similar to ergot, savine and rue). (Dried seeds constitute the drug Harmal of Indian medicine.)

The plant gave flavonoids—kaem- pferol, quercetin and acacetin. Aerial parts and seeds contain alkaloids— harmine, harmaline and harmalol (called harman alkaloids). Harman alkaloids from the seeds have been suggested for use in nervous diseases, and as coronary dilators and embolic. Harmol exhibits hypertensive activity. Harmine, vasicinone, deoxyvasici- none and 8-hydroxy glucosylharmine exhibit antitumour activity.

The alkaloids, harmine, harmaline and harmol exhibit antibacterial and antifungal activity.

The aqueous extract of seeds exhibited significant antiviral activity in vitro against herpes virus hominis type 1, slight activity was also observed against influenza viruses A and B. The plant extract exhibits significant analgesic activity.... peganum harmala

Pelargonium Graveolens

L'Hert.

Family: Geraniaceae.

Habitat: Introduced into India in the Shevroy hills of Tamil Nadu; cultivated largely in the Nilgiri and Palni hills of Tamil Nadu.

English: Geranium.

Action: Oil—antifungal.

Geranium oil produced from the plant grown in the temperate region at high altitudes is rich in menthone, cit- ronellol, nerol and geraniol; while the oil produced from the plants grown at lower altitudes is rich in isomenthone, linalool and citronellyl formate.

Geranium oil and its constituents are reported to exhibit marginal an- titumour activity.

The oil also exhibits in vitro antifun- gal activity.... pelargonium graveolens

Pele

(Hawaiian) From the volcano... pele

Peleka

(Hawaiian) Having great strength Pelekah, Pelika, Pelikah, Pelyka, Pelykah... peleka

Pelham

(English) One who is thoughtful Pellam, Pelhim, Pellham, Pelim... pelham

Pelia

(Hebrew) A marvelous woman Peliah, Peliya, Peliyah, Pelea, Peleah... pelia

Pelicia

(Greek) A weaving woman Peliciah, Pelicea, Peliciya, Pelycia, Pelycea... pelicia

Pelipa

(African) One who loves horses Pelypa, Peliepa, Peleipa, Peleepa, Peleapa... pelipa

Pellikita

(Latin) A bringer of happiness Pellikitah, Pelikita, Pellkita, Pelkita... pellikita

Pellitory-of-the-wall

Parietaria officinalis. N.O. Urticaceae.

Habitat: Old walls.

Features ? Up to two feet high, stem reddish, brittle, angular, rather hairy. Leaves alternate, stalked, lanceolate, edges smooth, one to two inches long by half an inch to one inch broad. Numerous pink flowers (June and July), small, axillar.

Part used ? Herb.

Action: Diuretic, laxative.

Gravel, suppression of urine, and other bladder and kidney disorders. Frequently prescribed in combination with Wild Carrot and Parsley Piert. Wineglass doses of the infusion of 1 ounce to 1 pint boiling water.... pellitory-of-the-wall

Pellonia

(Latin) A defender against enemies Pelloniah, Pelonia, Pellonea, Pelonea... pellonia

Pelopia

(Greek) In mythology, the wife of Thyestes and mother of Aegisthus Pelopiah, Pelopea, Pelopeah, Pelopiya... pelopia

Pelulio

(Hawaiian) A treasure from the sea Pelulia, Peluliyo, Peluliya... pelulio

Pemba

(African) A powerful woman Pembah, Pembia, Pembiah, Pembea, Pembeah... pemba

Pembroke

(English) From the broken hill Pembrook, Pembrok, Pembrooke... pembroke

Pemphredo

(Greek) An alarm; in mythology, one of the three Graces... pemphredo

Penardd Un

(Celtic) In mythology, the wife of Llyr... penardd un

Penca De

Means “leaf of (plant name)”; usually refers to the rigid, cactus-like leaves of agave or aloe; look up the plant name which follows this description of the plant part used.... penca de

Penda

(African) One who loves and is loved Pendah, Penha, Penhah... penda

Peltophorum Pterocarpum

Backer ex K. Heyne.

Family: Caesalpiniaceae.

Habitat: Coastal forests of the Andaman Islands.

English: Copper Pod, Rusty Shield-Bearer.

Siddha/Tamil: Ivalvagai, Perun- gondrai.

Action: Bark—used for dysentery; also used as a constituent of gargles, tooth-powders and lotions for sores and muscular pains.

The bark contains 20.8% of a catechol type of tannin and 9.5% non-tans. The wood and leaves also contain tannin.

The pods contain bergenin which exhibits anti-inflammatory activity in carrageenan-induced rat paw oedema and is found to be equipotent to phenylbutazone.

Aqueous extract of leaves and etha- nolic extract of flower exhibit antifun- gal activity.

Family: Asclepiadaceae.

Habitat: West Bengal, Gujarat and Peninsular India.

Ayurvedic: Kaakanaasaa, Kaakanaasikaa, Kaakaangi, Kaak- tundphalaa, Shringiritti.

Siddha/Tamil: Uppilankodi.

Folk: Singarauti (Gujarat). Amarvel.

Action: Plant—antifungal, antiseptic, keratolytic; used in various skin conditions.

The plant gave n-octacosanol, alpha- amyrin, friedelin, beta-sitosterol. An appreciable amount of salicyclic acid has been isolated from the plant. The plant also yields a cardiac glycoside.

Dosage: Plant—50-100 ml. decoction. (CCRAS.)... peltophorum pterocarpum

Pelvic Inflammatory Disease(pid)

An infection of the endometrium (membraneous lining) of the UTERUS, FALLOPIAN TUBES and adjacent structures caused by the ascent of micro-organisms from the vulva and vagina. Around 100,000 women develop PID each year in the UK; most of those affected are under 25 years of age. Infection is commonly associated with sexual intercourse; Chlamydia trachomatis (see CHLAMYDIA) and Neisseria gonorrhoeae (see NEISSERIACEAE) are the most common pathogens. Although these bacteria initiate PID, opportunistic bacteria such as STREPTOCOCCUS and bacteroides often replace them.

The infection may be silent – with no obvious symptoms – or symptoms may be troublesome, for example, vaginal discharge and sometimes a palpable mass in the lower abdomen. If a LAPAROSCOPY is done – usually by endoscopic examination – overt evidence of PID is found in around 65 per cent of suspected cases.

PID may be confused with APPENDICITIS, ECTOPIC PREGNANCY – and PID is a common cause of such pregnancies – ovarian cyst (see OVARIES, DISEASES OF) and in?ammatory disorders of the intestines. Treatment is with a combination of ANTIBIOTICS that are active against the likely pathogens, accompanied by ANALGESICS. Patients may become seriously ill and require hospital care, where surgery is sometimes required if conservative management is unsuccessful. All women who have PID should be screened for sexually transmitted disease and, if this is present, should be referred with their partner(s) to a genito-urinary medicine clinic. Up to 20 per cent of women who have PID become infertile, and there is a seven-to ten-fold greater risk of an ectopic pregnancy occurring.... pelvic inflammatory disease(pid)

Pendant

(French) A decorated woman Pendent, Pendante, Pendente... pendant

Penelope

(Greek) Resembling a duck; in mythology, the faithful wife of Odysseus Peneloppe, Penelopy, Penelopey, Penelopi, Penelopie, Penelopee, Penella, Penelia, Pen, Penn, Penne, Penny, Pennie, Penni, Penney, Peni, Pennea, Penelopea... penelope

Penninah

(Hebrew) Resembling a precious stone

Penina, Peninah, Peninna, Penyna, Pennyna, Penine, Penyne... penninah

Pennsylvania

(English) The land of Penn; from the state of Pennsylvania... pennsylvania

Pensee

(French) A thoughtful woman Pense, Pensi, Pensie, Pensy, Pensey, Pensea... pensee

Pentapetes Phoenicea

Linn.

Family: Sterculiaceae.

Habitat: A shrub cultivated as an ornamental throughout the hotter parts of India.

Ayurvedic: Bandhujiva, Bandhuuka, Arkavallabha.

Folk: Gul-dupahariaa.

Action: Capsule—mucilaginous, used for the diseases of the bowels; a decoction is used as emollient. Root—astringent, antibilious, antiphlegmonous, febrifuge.... pentapetes phoenicea

Penthea

(Greek) The fifth-born child Penthia, Pentheah, Penthiah, Penthiya, Penthiyah... penthea

Penthesilea

(Greek) In mythology, a queen of the Amazons... penthesilea

Pepin

(French) An awe-inspiring woman Peppin, Pepine, Peppine, Pipin, Pippin, Pepen, Pepan, Peppen... pepin

Pentatropis Microphylla

W. & A.

Synonym: P. capensis (Linn. f.) Bullock.

Synonym: P. cynanchoides R. Br.

Family: Asclepiadaceae.

Habitat: A climber found in Punjab, Delhi, Upper Gangetic Plain, Rajasthan and Gujarat.

Ayurvedic: Kaakanaasaa (related species).

Folk: Ambarvel, Vanaveri (Punjab).

Action: Root—astringent, antigon- orrhoeic, alterative. Plant—emetic, purgative.

An acyclic diterpene ester, cis-phy- tyl-l-palmitate, together with the triter- penes, squalene, n-taraxasterol and taraxasterol, has been isolated from the plant.... pentatropis microphylla

Pepita

(Spanish) Feminine form of Joseph; God will add

Pepitah, Pepitta, Pepitia, Pepitina... pepita

Pepper Tree

Purification, Healing, Protection... pepper tree

Peppy

(American) A cheerful woman Peppey, Peppi, Peppie, Peppee, Peppea... peppy

Peptonised Foods

Foods which have been predigested by PANCREATIN and thereby rendered more digestible.... peptonised foods

Perach

(Hebrew) A flourishing woman Pericha, Percha, Pircha, Perchiya, Pirchiya... perach

Perahta

(German) A glorious woman Perata, Perchta, Perchte... perahta

Peppermint Tea

Peppermint is a fragrant herb that makes for a soothing drink. Peppermint helps you digest foods better and also reduces flatulence and digestive issues. Peppermint is prescribed to people with IBS (irritable bowel syndrome) and gallstones in capsules. A cup of peppermint tea will ease nausea and vomiting, especially if you suffer motion sickness. If you have heartburn, don’t drink peppermint tea as this might aggravate your condition. Peppermint tea brings down the severity of herpes outbreaks. The natural mint flavor of the herb helps to freshen your breath. Other health benefits of this tea are control of muscle aches and chronic pain, clearing of congestion and mild coughs, mild asthma and reduction of stress.... peppermint tea

Percentage

The proportion multiplied by 100. See “proportion”.... percentage

Percentile

The set of numbers from 0 to 100 that divide a distribution into 100 parts of equal area, or divide a set of ranked data into 100 class intervals, with each interval containing 1/100 of the observations. For example, the 5th percentile, is a cut point with 5% of the observations below it and the remaining 95% of the observations above it.... percentile

Percutaneous Transhepatic Cholangiopancreatography (ptc)

A technique for displaying the bile ducts (see BILE DUCT) and pancreatic ducts (see PANCREAS) with radio-opaque dyes. These are introduced via a catheter (see CATHETERS) inserted into the ducts through an incision in the skin. An X-ray is then taken of the area.... percutaneous transhepatic cholangiopancreatography (ptc)

Perdita

(Latin) A lost woman Perditah, Perditta, Perdy, Perdie, Perdi, Perdee, Perdea, Perdeeta, Perdeata... perdita

Perdix

(Latin) Resembling a partridge Perdixx, Perdyx, Perdyxx... perdix

Peregrina

(Latin) A traveler; a wanderer Peregrine, Peregrinna, Peregrinia, Peregrinea, Perrin... peregrina

Perel

(Latin) One who has been tested Perell, Perelle, Perela, Perele, Perella... perel

Perfecta

(Spanish) One who is flawless Perfecte, Perfectia, Perfectea, Perfect, Perfection... perfecta

Performance

The level of attainment of a goal in comparison to a given effort.... performance

Performance Criteria

Criteria to be used to measure/assess performance.... performance criteria

Performance Measure Or Indicator

Methods or instruments to estimate or monitor the extent to which the actions of an individual practitioner or whole programme conform to practice standards of quality or allow comparisons between services.... performance measure or indicator

Performance- Qualification

Documented verification of the appropriateness of critical process parameters, operating ranges and system reproducibility over an appropriate time period... performance- qualification

Pergularia Extensa

N. E. Br.

Synonym: P. daemia (Forsk.) Chiov.

Family: Asclepiadaceae; Periplo- caceae.

Habitat: Throughout India and hotter parts.

English: Hairknot Plant, Whitlow Plant.

Ayurvedic: Uttamaarani, Vrischikaali, Vishaanikaa. Phala- kantaka. Ajashringi is a doubtful synonym.

Siddha/Tamil: Utthaamani, Veli- paruthi.

Folk: Utaran.

Action: Plant—Uterine stimulant, tones up urinary bladder, stimulates gastric secretion, expectorant, emetic. Leaf—used for amenorrhoea, dysmenorrhoea; externally applied to carbuncles.

The plant gave betaine, a polypep- tide, hentriacontane, lupeol, alpha-and beta-amyrin, beta-sitosterol as major constituents. Seeds and stems gave car- denolides—calactin, calotropin, calo- tropagenin, uzarigenin and coroglau- cigenin.

The plant extract exhibits stimulating action on uterine and other involuntary muscles. The extracts cause rise in arterial blood pressure, increase in movement and tone of urinary bladder, and stimulation of gastric secretions. An aqueous extract of the leaves shows antibacterial activity against E. coli and Micrococcus pyogenes var. aureus.... pergularia extensa

Periapical Abscess

An abscess or pus pocket around the apex of the root of a tooth...sometimes called a gumboil... periapical abscess

Pericampylus Glaucus

(Lam.) Merill.

Family: Menispermaceae.

Habitat: Hill forests of Sikkim, Northern Bengal and Assam.

Folk: Baarak-kaant (Maharashtra), Goriaa-loti (Assam).

Action: Leaves—an infusion is used for asthma and high fever. Pounded leaves are applied in headache. The mucilage in water is used for arresting falling of hair.

The bark contains a non-toxic principle. The root is reported to contain a narcotic alkaloid.... pericampylus glaucus

Peridot

(Arabic) One who is treasured... peridot

Perilepta Auriculata

(Nees) Bremek.

Synonym: Strobilanthes auriculatus Nees.

Family: Acanthaceae.

Habitat: Upper Gangetic Plain, Madhya Pradesh.

Siddha/Tamil: Kurinji.

Folk: Pandadi (Gujarat).

Action: Pounded leaves—rubbed on body during the cold stage of intermittent fever.... perilepta auriculata

Period

See MENSTRUATION.... period

Perilla Frutescens

(Linn.) Britton.

Family: Labiatae; Lamiacae.

Habitat: Throughout the Himalayas up to an altitude of about 3,500 m, and in the hills of Assam.

English: Perilla, Wild Coleus.

Folk: Bhanjeer, Ban-tulasi, Ban- jiraa, Bhasindi.

Action: Herb—sedative, antispasmodic, antiasthmatic, resolvent.

P. frutescens var. crispa is used in mixtures prescribed for cough and lung affections.

Several chemotypes of Perilla have been detected. The Indian type is rich in rosefuran. Other components are perillene, perilla ketone, beta-caryo- phyllene, phellandrene and a few ses- quiterpenoids. Aerial parts gave ethyl linolenate, linolenic acid and beta- sitosterol. The leaves also gave an an- thocyanin, perillanin. The leaves and flowering tops yield essential oils containing perilla ketone as major com- ponent—94% in leaf oils and 47% in inflorescence oils at fruiting stage.

Perillaldehyde, a major component of the plant extract, inhibits (moderately) a broad range of both bacteria and fungi. The MeOH extract of var. acuta Kudo is reported to prolong hexobarbital-induced sleep in mice. Dillapiol has been isolated as the active principle from the methanolic extract.... perilla frutescens

Perinatal Mortality

Perinatal mortality consists of deaths of the FETUS after the 28th week of pregnancy and deaths of the newborn child during the ?rst week of life. Today, more individuals die within a few hours of birth than during the following 40 years. It is therefore not surprising that the perinatal mortality rate, which is the number of such deaths per 1,000 total births, is a valuable indicator of the quality of care provided for the mother and her newborn baby. In 2002, the perinatal mortality rate was 7.87 in the United Kingdom compared with 11.4 in 1982 – and over 30 in the early 1960s.

The causes of perinatal mortality include extreme prematurity, intrapartum anoxia (that is, di?culty in the birth of the baby, resulting in lack of oxygen), congenital abnormalities of the baby, and antepartum anoxia (that is, conditions in the terminal stages of pregnancy preventing the fetus from getting su?cient oxygen).

The most common cause of perinatal death is some complication of placenta, cord or membranes. The next most common is congenital abnormality. Intrauterine hypoxia and birth asphyxia comprise the third most common cause.... perinatal mortality

Perioperative Cell Salvage

A method of autologous blood TRANSFUSION – using a patient’s own blood, salvaged during a surgical operation – instead of conventional blood-bank transfusion.... perioperative cell salvage

Peripheral

At the edges, especially circulation or nerves. Peripheral functions are usually controlled and modified more by local conditions than systemic (central) controls.... peripheral

Peripheral Neuritis

In?ammation of the nerves (see NERVE) in the outlying parts of the body. (See NEURITIS.)... peripheral neuritis

Periploca Aphylla

Decne.

Family: Asclepiadaceae; Periplo- caceae.

Habitat: Punjab and Rajasthan.

Folk: Barri (Punjab).

Action: Plant—stomachic; used in cerebral fever. Bark—purgative. Latex—used against tumours and swellings.

The leaves and stems contain 2.2% of resin alcohol, a bitter substance, tannin and small quantities of a glucosidal principle which produces first a decrease and then an increase in blood pressure. The bark contain 8% tannin.... periploca aphylla

Peritoneoscopy

See LAPAROTOMY.... peritoneoscopy

Peripheral-blood Stem-cell Transplants

These have almost completely replaced BONE MARROW TRANSPLANT, used to treat malignancies such as LEUKAEMIA and LYMPHOMA for the past 20 years. The high doses of CHEMOTHERAPY or RADIOTHERAPY used to treat these diseases destroy the bone marrow which contains stem cells from which all the blood cells derive. In 1989 stem cells were found in the blood during recovery from chemotherapy. By giving growth factors (cytokines), the number of stem cells in the blood increased for about three to four days. In a peripheral-blood stem-cell transplant, these cells can be separated from the peripheral blood, without a general anaesthetic. The cells taken by either method are then frozen and returned intravenously after the chemotherapy or radiotherapy is completed. Once transplanted, the stem cells usually take less than three weeks to repopulate the blood, compared to a month or more for a bone marrow transplant. This means that there is less risk of infection or bleeding during the recovery from the transplant. The whole procedure has a mortality risk of less than 5 per cent – half the risk of a bone marrow transplant.... peripheral-blood stem-cell transplants

Periploca Calophylla

Falc.

Family: Asclepiadaceae.

Habitat: The Himalayas, from Kashmir to Nepal and Meghalaya, ascending to 1,800 m.

Ayurvedic: Krishna Saarivaa (substitute). (Cryptolepis buchanani is equated with Krishna Saarivaa.)

Action: Used in place of Cryptolepis buchanani and Hemidesmus indicus for rheumatism, urinary and skin diseases.

The glycosides locin, plocin, ploci- nin, calocin, calocinin, as well as triter- penoids, have been reported from the twigs.... periploca calophylla

Peristrophe Bicalyculata

Nees.

Family: Acanthaceae.

Habitat: Distributed throughout India.

Ayurvedic: Nadikaantaa, Praachibalaa, Sulomshaa, Kaakatik- ta, Kaakajanghaa. (Aatarilaal is a wrong synonym. It is equated with Anthriscus cerefolium Hoffm., used in Unani medicine.)

Siddha/Tamil: Chebisa.

Action: Plant—febrifuge. The essential oil shows tuberculostatic activity in vitro. It inhibits the growth of various strains of Mycobaterium tuberculosis.

Ayurvedic Pharmacopoeia of India recommends the dried root in insomnia and for fear-psychosis in children.

Dosage: Root—1-5 g powder. (API, Vol III.)... peristrophe bicalyculata

Perlace

(Spanish) Resembling a small pearl Perlase, Perlaice, Perlaise, Perlayce, Perlayse... perlace

Perlette

(French) Resembling a small pearl Perlett, Perlet, Perlete, Perleta, Perletta... perlette

Perlie

(Latin) Resembling a pearl Perli, Perly, Perley, Perlee, Perlea, Perleigh... perlie

Perlina

(American) Resembling a small pearl Perlinah, Perlyna, Perlynah, Perleena, Perleenah, Perleana, Perleanah, Perliena, Perlienah, Perleina, Perleinah... perlina

Pernella

(Scandinavian) As solid as a rock Pernell, Pernela, Pernele, Pernel, Pernelle... pernella

Peron

(Latin) One who travels... peron

Perouze

(Armenian) Resembling the turquoise gem

Perooze, Perouse, Peroose, Perouza, Perousa... perouze

Perpetua

(Latin) One who is constant; steadfast... perpetua

Perse

(Greek) From the water; in mythology, one of the Oceanids Persa, Perseis... perse

Persea Americana

Mill.

Synonym: P. gratissima Gaertn. f.

Family: Lauraceae.

Habitat: Native to Central America; introduced into India and grown for its fruit in Bangalore, Nandi Hills, Courtallam, Nagarcoil, Shevaroys, lower Palnis and the foothills of the Nilgiris; also in Pune.

English: Avocado, Alligator Pear, Butter Fruit.

Action: Fruit—hypocholestero- laemic. Leaf—bacteriostatic; potentially toxic to goats and sheep.

The fruit is highly nutritious. The fruit from Nilgiris contains 22.8% fat, 1.7% protein; also manganese, phosphorus, iron, potassium, vitamin E, vitamin C, beta-carotene, thiamine, ri- boflavin, nicotinic acid and foliate. It is relatively low in sodium and simple sugars.

American Avocado is rich in oil (1530 g/100 g fresh fruit) that is mainly monounsaturated and a good source of linoleic acid. Its high fiber content might be responsible for its cholesterol lowering effects.

Preliminary evidence suggests that unsaponifiable fractions of Avocado and soybean oils (combination) can inhibit cartilage degradation and promote cartilage repair in osteoarthritic chondrocytes. (Properties of Avocado cited in Natural Medicines Comprehensive Database, 2007.) Avocado oil is used in cosmetic preparations, soaps and pharmaceuticals. The peel of immature fruit contains antifungal compounds. The fruit pulp is used topically to promote hair growth.... persea americana

Persea Macrantha

(Nees) Kosterm.

Synonym: Machilus macrantha Nees.

Family: Lauraceae.

Habitat: Bihar and Peninsular India, up to 2,100 m.

English: Machilus.

Action: Bark—antiasthmatic, antirheumatic, purgative.

The root gave phytosterols, glyco- sides and alkaloids, the major one being machiline, shown to be identical with dl-coclaurine. Machiline exhibits hypotensive activity.

The leaves are used in external applications for ulcers.... persea macrantha

Persephone

(Greek) In mythology, the daughter of Demeter and Zeus who was abducted to the underworld Persephoni, Persephonie, Persephony, Persephoney, Persephonee, Persefone, Persefoni, Persefonie, Persefony, Persefoney, Persefonee... persephone

Pershella

(American) A generous woman Pershela, Pershel, Pershell, Pershele, Pershelle... pershella

Persis

(Greek) Woman of Persia Persiss, Persisse, Persys, Persyss, Persysse... persis

Persistent Chronic Diarrhoea

Diarrhoea that begins acutely but lasts more than 21 days. The usual enteropathogens are Shigella spp., Salmonella spp., Campylobacter jejuni, Yersinia enterocolitica, Capillaria philippinensis, Cryptosporidium. Giardia can also be a cause.... persistent chronic diarrhoea

Person/vector Contact

The number of times a person is bitten by a vector mosquito, normally expressed as the number of bites per person per night.... person/vector contact

Personal Care

Assistance with those functions and activities normally associated with body hygiene, nutrition, elimination, rest and ambulation, which enables an individual to live at home or in the community.... personal care

Personal Care Plan

See “care plan”.... personal care plan

Perzsi

(Hebrew) A woman devoted to God Perzsie, Perzsy, Perzsee, Perzsike, Perke, Perzsey, Perzsea... perzsi

Persistent Vegetative State (pvs)

PVS may occur in patients with severe brain damage from HYPOXIA or injury. Patients do not display any awareness of their surroundings, and are unable to communicate. Sleep alternates with apparent wakefulness, when some re?exes (see REFLEX ACTION) may be present: for example, patients’ eyes may re?exly follow or respond to sound, their limbs can re?exly withdraw from pain, and their hands can re?exly grope or grasp. Patients can breathe spontaneously, and retain normal heart and kidney function, although they are doubly incontinent (see INCONTINENCE).

For a diagnosis of PVS to be made, the state should have continued for more than a prede?ned period, usually one month. Half of patients die within 2–6 months, but some can survive for longer with arti?cial feeding. To assess a person’s level of consciousness, a numerical marking system rated according to various functions – eye opening, motor and verbal responses – has been established called the GLASGOW COMA SCALE.

The ETHICS of keeping patients alive with arti?cial support are controversial. In the UK, a legal ruling is usually needed for arti?cial support to be withdrawn after a diagnosis of PVS has been made. The chances of regaining consciousness after one year are slim and, even if patients do recover, they are usually left with severe neurological disability.

PVS must be distinguished from conditions which appear similar. These include the ‘LOCKED-IN SYNDROME’ which is the result of damage to the brain stem (see BRAIN). Patients with this syndrome are conscious but unable to speak or move except for certain eye movements and blinking. The psychiatric state of CATATONIA is another condition in which the patient retains consciousness and will usually recover.... persistent vegetative state (pvs)

Pesha

(Hebrew) A flourishing woman Peshah, Peshia, Peshiah, Peshea, Pesheah, Peshe... pesha

Pessaries

(1) A plastic device placed in the VAGINA designed to support a displaced UTERUS.

(2) A suppository suitably shaped for insertion into the vagina. Made of oil of theobromine or a glycerin basis, they are used for applying local treatment to the vagina.... pessaries

Pethidine Hydrochloride

A synthetic analgesic and antispasmodic drug, which is used in the treatment of painful and spasmodic conditions in place of morphine and atropine. A prompt but short-lasting analgesic, it has less of a constipating e?ect than morphine but is less potent. Useful for analgesia during childbirth because it produces less respiratory depression in the baby than other opioids. Pethidine is one of the CONTROLLED DRUGS.... pethidine hydrochloride

Petiveria Alliacea

Linn.

Habitat: Native to America; introduced into India, grown in gardens.

Action: Root—diuretic, antispas- modic, emmenagogue, abortifa- cient. Used for whooping cough, also for rheumatism and nervous diseases. (Long term use in high doses causes brain damage.)

Ethanolic extract of the leaves contains leridal, leridol, 5-O-methylleri- dol and 3-O-rhamnosides of dihydro- kaempferol, dihydroquercetin and my- ricetin. The presence of high nitrate content in the plant has been reported and is considered a risk factor in humans.... petiveria alliacea

Petri Dishes

Shallow, circular glass dishes, usually 10 cm in diameter, which are used in bacteriology laboratories for the growth of micro-organisms.... petri dishes

Petronela

(Latin) Feminine form of Peter; as solid and strong as a rock Petronella, Petronelle, Petronia, Petronilla, Petronille, Petrona, Petronia, Petronel, Petronele, Pernila, Pernilla, Parnella, Pedra, Petra, Petrine, Pedrine, Perrine, Peirene, Peronel, Peronelle, Peta, Pier, Piera, Pierra, Pierce, Pierette, Pietra, Pita... petronela

Petroselinum Crispum

(Mill.) Airy-Shaw.

Synonym: Apium crispum Mill.

Family: Umbelliferae; Apiaceae.

Habitat: Native to Europe, now cultivated throughout India.

English: Parsley.

Unani: Fitraasaaliyum, Karafs-e- Kohi.

Action: Diuretic (used for bladder disorders, painful urination, retention of excess fluid in the tissues), antispasmodic, uterine tonic, emmenagogue, sedative (used for PMS and menopausal hot flushes, also in prostatitis), carminative, expectorant, aperient, antiseptic, anti-inflammatory.

Key application: For flushing out the efferent urinary tract in disorders of the same and in prevention and treatment of kidney gravel. (German Commission E.) Contraindicated in kidney inflammations.

The British Herbal Compendium approves the internal use of the herb for flatulent dyspepsia, dysuria and rheumatic conditions.

The leaves and roots contain furo- coumarins—psoralen, 5-and 8-meth- oxy psoralen, imperatorin, oxypeuce- danin, iso-pimpinelin. Myristicin has been isolated from the leaf oil. The plant gave flavonoids—apiin, luteolin, apigenin-7-glucoside, luteolin-7-glu- coside among others.

Myristicin showed high activity as an inducer of the detoxifying enzyme system, Glutathione S-transferase (GST) in the liver and small intestines of female mice (may be considered as a cancer chemoprotective agent).

The flavonoids, particularly api- genin, have been shown to be anti- inflammatory, to inhibit histamine release and to act as a free radical scavenger. Apiole, a constituent of the volatile oil, is reportedly antipyretic and phthalides of the root, seed and leaf are sedative in mice.

Both apiole and myristicin exhibit aquaretic and uterine stimulant activity, while sodium retention has been observed. (Natural Medicines Comprehensive Database, 2007.)

In homoeopathy, the herb is used for the treatment urinary disorders—sudden urge to urinate with severe pain, dribbling of urine after urination, gleet discharge and for amenorrhoea and neuralgic dysmenorrhoea.... petroselinum crispum

Petula

(Latin) An impatient woman Petulah, Petulla, Petoola, Petoula... petula

Petunia

(English) Resembling the flower Petuniah, Petuniya, Petunea, Petoonia, Petounia... petunia

Peucedanum Grande

C. B. Clarke.

Family: Umbelliferae; Apiaceae.

Habitat: Western Ghats and hills of Peninsular India.

Folk: Baaphali (Gujarat), Duku.

Action: Fruits—carminative, diuretic, stimulant. An infusion is used for gastric and intestinal troubles.

The seeds and roots gave imperatorin, byakangelicin and osthol. Seeds, in addition, gave phelopterin, colum- bianadin and byakangelicol.... peucedanum grande

Peyronie’s Disease

Painful and deformed erection of the PENIS caused by the formation of ?brous tissue. The cause is unknown but it may be associated with DUPUYTREN’S CONTRACTURE. The condition may be improved by surgery.... peyronie’s disease

Peyton

(English) From the warrior’s village Peyten... peyton

Phaedra

(Greek) A bright woman; in mythology, the wife of Theseus Phadra, Phaidra, Phedra, Phaydra, Phedre, Phaedre... phaedra

Phan

(Asian) One who shares with others... phan

Phantasy

The term applied to an imaginary appearance or daydream.... phantasy

Pharmacists

Health professionals trained in the preparation and dispensing of medicines; in England, Scotland and Wales they are registered (after acquiring the relevant professional quali?cations) by the Royal Pharmaceutical Society. Northern Ireland has its own registration body. Registered pharmacists are a vital branch of health care. They dispense P (pharmacy-only) and POM (prescription-only medicines) products; those working in community (retail) pharmacies also sell over-the-counter (OTC) drugs, providing, where appropriate, advice on their use. (See also MEDICINES.)

Pharmacists work in hospitals (NHS and private) and in community pharmacies, as well as in the pharmaceutical industry where they conduct research and prepare and test pharmaceutical products. They have particular expertise on the use of drugs: for instance, the way in which one medicinal compound can affect another and their possible adverse effects; and they advise doctors and patients on these aspects. The NHS is also encouraging community pharmacists to o?er the public advice on the treatment of simple illnesses such as coughs, colds, headaches and stomach upsets. Hospital pharmacists are salaried employees of the NHS but community pharmacists enter into contract with the service, the terms of which are negotiated centrally between pharmacists’ representatives and the health departments. Hospital pharmacists are now invited by the COMMITTEE ON SAFETY OF MEDICINES (CSM) to report suspected adverse drug reactions under the ‘Yellow Card’ scheme in the same way as doctors.... pharmacists

Pharmacogenetics

See PHARMACOGENOMICS.... pharmacogenetics

Pharyngodynia

Pain in the pharynx... pharyngodynia

Pharyngopathy

Any disease of the pharynx... pharyngopathy

Phaseolus Aconitifolius

Jacq.

Synonym: Vigna aconitifolia (Jacq.) Marechal.

Family: Papilionaceae; Fabaceae.

Habitat: Throughout India. Cultivated.

English: Aconite-Bean, Moth.

Ayurvedic: Makushtha, Moth.

Siddha/Tamil: Tulukkapayir.

Action: Seeds—used as a diet in fever; contains 24.4% protein. Root—narcotic.... phaseolus aconitifolius

Phaseolus Adenanthus

G. F. W. Mey.

Family: Papilionaceae; Fabaceae.

Habitat: Throughout India, in the plains.

Ayurvedic: Aranya-mudga. Mudga- parni (Kerala).

Siddha/Tamil: Kattupayaru.

Action: A decoction is used in bowel complaints and stricture. The roots are used to stop excessive salivation.... phaseolus adenanthus

Phaseolus Lunatus

Linn.

Synonym: P. inamoenus Linn.

Family: Fabaceae.

Habitat: Native to tropical America; cultivated throughout India.

English: Double Bean, Lima Bean, Burma Bean.

Ayurvedic: Shimbi.

Unani: Lobiyaa, Sem.

Action: Seeds—astringent. Used as a diet in fever. The shoots and pods from Manipur are reported to contain alkaloids, saponins and flavonoids.... phaseolus lunatus

Phashestha

(American) One who is decorated

Phashesthea, Phashesthia, Phashesthiya... phashestha

Pheakkley

(Vietnamese) A faithful woman Pheakkly, Pheakkli, Pheakklie, Pheakklee, Pheakkleigh, Pheakklea... pheakkley

Pheba

(Greek) One who smiles a lot Phebah, Phiba, Phibah... pheba

Pheme

(Greek) In mythology, the personification of fame

Phemie, Phemia, Phemi, Phemy, Phemey, Phemee, Phemea... pheme

Phenazocine Hydrobromide

A powerful analgesic which can be given under the tongue if nausea and vomiting are a problem.... phenazocine hydrobromide

Phenice

(American) One who enjoys life Phenyce, Phenise, Phenyse, Phenicia, Phenicea... phenice

Phenobarbitone

The British Pharmacopoeia name for one of the most widely used of all the group of drugs called BARBITURATES. It was mainly used in combination with PHENYTOIN SODIUM as an anticonvulsant drug in the control of EPILEPSY, but has been superceded largely by newer and safer anti-epileptic drugs.... phenobarbitone

Phaseolus Mungo

Linn. non-Roxb. & auct.

Synonym: Vigna mungo (Linn.) Hepper.

Family: Papilionaceae; Fabaceae.

English: Kidney Bean, Black Gram.

Ayurvedic: Maasha. (P. sublobatus Roxb. and Teramnus labialis Spreng. are equated with Maashaparni; dried aerial parts are used.) Phaseolus dalzellii Cooke and P. sublobatus Roxb. are known as Maashaparni in Kerala.

Unani: Urd-Siyaah.

Siddha/Tamil: Ulunthu.

Action: Used as a pulse. In the form of a confection, used for leucorrhoea and seminal debility. Oil extracts of the pulse is used externally in rheumatism, contracted knee, stiff shoulder. Root—used as a poultice for inflammations and abscesses. Narcotic.

Teramnus labialis Spreng. (grows wild): The whole plant is used in rheumatism, paralysis, nervous diseases, haemoptysis and catarrh of respiratory tract.... phaseolus mungo

Phaseolus Radiatus

Linn. non-Roxb. & auct.

Vigna radiata (Linn.)

Family: Papilionaceae; Fabaceae.

Habitat: Extensively cultivated all over India.

English: Greengram, Golden Gram.

Ayurvedic: Mudga, Mungalya.

Unani: Moong.

Siddha/Tamil: Pattishai-payaru.

Action: Used as a pulse. Soup is given as a diet to patients of enlarged liver and spleen, and after recovery from acute illness. A poultice of it is used for checking secretion of milk and reducing distention of the mammary glands.... phaseolus radiatus

Phaseolus Trilobus

sensu Ait. & auct.

Synonym: Vigna trilobata (Linn.) Verdcourt.

Family: Papilionaceae; Fabaceae.

Habitat: Throughout India, up to an elevation of 2,100 m in the northeast.

English: Wild Gram.

Ayurvedic: Mudgaparni, Kaaka- parni, Suuryaparni, Alpikaa, Sahaa, Kaakamudraa, Maarjaargandhikaa. (P. adenanthus G. F. W., and Vigna pilosa Baker are used as Mudgaparni in the South. Dried aerial parts, root and seed are used.)

Siddha/Tamil: Kaatupayaru.

Folk: Jangali Moong, Mugavan.

Action: Whole plant—febrifuge. Leaves—sedative, cooling, an- tibilious. A decoction is used in intermittent fever. The plant contains friedelin, epifriedelin, stigmasterol and tannins. The bean contains methionine, tryptophan and tyrosine; also strepogenin, uridine, diphosphate-galacturonic acid. The seed protein contained lysine, valine, leucine and phenyl- alanine.

Dosage: Seed—50-100 ml. decoction (CCRAS.); whole plant— 3-5 g. (API, Vol. IV.)... phaseolus trilobus

Phaseolus Vulgaris

Linn.

Synonym: P. nanus Linn.

Family: Fabaceae.

English: Kidney Bean, French Bean, Haricot Bean.

Unani: Raajmah (seed), Lobia, Frashbean.

Action: Bean—diuretic, hypotensive, resolvent, regulates blood sugar. Used for water retention; albuminuria, especially of pregnancy; premenstrual tension.

Key application: Seed-free pods—in supportive treatment for inability to urinate. (German Commission E.)

The seeds of French Bean contain triterpenoid glucosides and soyasaponin V.

Raajmah consumption by diabetic patients is reported to produce highly significant reduction in their blood glucose level and glycaemic index, as compared to wheat and rice consumption.

Raw bean contains lectins which are destroyed when cooked. Its hypogly- caemic activity is most likely due to its chromium, trigonelline and fiber content. (Sharon M. Herr.)... phaseolus vulgaris

Phenothrin

See PERMETHRIN.... phenothrin

Phenyo

(African) A victorious woman... phenyo

Phenytoin Sodium

An older drug for the treatment of EPILEPSY. It is not now widely used, as it is di?cult to determine the precise dose to avoid ill-effects and long-term use leads to changes to the facial appearance. However, the drug is still used for the quick control of an apparently uncontrollable epileptic ?t, and after head injury or neurosurgery.... phenytoin sodium

Pheodora

(Greek) A supreme gift Pheodorah, Phedora, Phedorah... pheodora

Phernita

(American) A well-spoken woman Pherneeta, Phernyta, Phernieta, Pherneita, Pherneata... phernita

Pheromones

Chemicals produced and emitted by an individual which produce changes in the social or sexual behaviour when perceived by other individuals of the same species. The precise role of these odours – for it is by their smell that they are recognised – in humans is still not clear, but there is growing evidence of the part they play in the animal kingdom. Thus, if a strange male rat is put into a group of female rats, this may cause death of the fetus in any pregnant rats, and this is attributed to the pheromones emitted by the male rat.... pheromones

Phia

(Italian) A saintly woman Phiah, Phea, Pheah... phia

Philadelphia

(Greek) One who offers sisterly love

Philly, Phillie, Philli, Philley, Phillee, Phillea... philadelphia

Philana

(Greek) One who adores mankind Philena, Philanna, Philanne, Philenne, Philenna, Philene, Phileane, Phileene... philana

Philantha

(Greek) A woman who loves flowers

Philanthia, Philanthea, Philanthiya... philantha

Philberta

(English) Feminine form of Philibert; one who is dearly loved Philiberta, Philbertha, Philibertha, Philberte, Philiberte, Philiberthe, Philberthe... philberta

Phile

(Greek) Feminine form of Philo; one who loves and is loved Phila... phile

Philippa

(English) Feminine form of Philip; a friend of horses

Phillippa, Philipa, Phillipa, Philipinna, Philippine, Phillipina, Phillipine, Pilis, Pippa... philippa

Philise

(Greek) A loving woman Phileese, Philease, Phileise, Philiese, Philyse, Philese... philise

Philomel

(Greek) Resembling a nightingale Philomela, Philomele, Philomell, Philomelle, Philomella... philomel

Philomena

(English) A friend of strength Philomina, Philomeena, Philomyna, Philomenia, Philominia, Philomeenia, Philomynia, Phiomeana... philomena

Philyra

(Greek) A woman who loves music Philyre, Philyria, Philyrea... philyra

Phiona

(Scottish) Form of Fiona, meaning “one who is fair; a white-shouldered woman”

Phionna, Phyona, Phyonna, Phione, Phionne, Phyone, Phyonne... phiona

Phira

(Greek) One who loves music Phirah, Pheera, Pheerah, Phiera, Phierah, Pheira, Pheirah, Pheara, Phearah... phira

Phlebotomine

A group of biting flies commonly called sandflies including the genus Phlebotomus, sometimes vectors of leishmaniasis.... phlebotomine

Phlogacanthus Thyrsiflorus

Nees.

Family: Acanthaceae.

Habitat: The sub-tropical Himalayas, Upper Gangetic Plain, Bihar, North Bengal and Assam.

Folk: Dieng-soh kajut (Meghalaya), Chuhai (Bihar), Titaaphul (Assam).

Action: Whole plant—used like Adhatoda vasica in whooping cough and menorrhagia. Fruits and leaves—burnt and prescribed for fevers. The leaves are reported to contain diterpene lactone, phlogantholide A and its glucoside.

A related species, P. jenkinsii C. B. Clarke, found in Assam, is also known as Titaaphul. A decoction of leaves is given for diseases of spleen and liver and for fevers.... phlogacanthus thyrsiflorus

Phlyctenule

A HYPERSENSITIVITY reaction of the conjunctiva (see EYE). At the turn of the century the most common cause was TUBERCULOSIS; nowadays it is most commonly due to hypersensitivity to staphylococci (see STAPHYLOCOCCUS).... phlyctenule

Phoebe

(Greek) A bright, shining woman; in mythology, another name for the goddess of the moon

Phebe, Phoebi, Phebi, Phoebie, Phebie, Pheobe, Phoebee, Phoebea, Phebee, Phebea... phoebe

Phoena

(Greek) Resembling a mystical bird Phoenah, Phoenna, Phena, Phenna... phoena

Phoenix

(Greek) A dark-red color; in mythology, an immortal bird Phuong, Phoenyx... phoenix

Phoenix Dactylifera

Linn.

Family: Palmae; Arecaceae.

Habitat: Cultivated in Punjab and Rajasthan.

English: Date Palm.

Ayurvedic: Kharjuura, Kharjuuraka, Kharjuurikaa. Pindakharjuurikaa. Chhuhaaraa (dry date). Pindakhar- juura is the fruit of Phoenix acaulis Roxb.

Unani: Khurmaa, Khajuur, Chhuharaa.

Siddha/Tamil: Perichchankay, Ita.

Action: Fruit pulp—antitussive, expectorant, demulcent, laxative, diuretic, restorative. Sap—cooling, laxative. Gum—used in diarrhoea and genitourinary diseases.

The fruit contains ascorbic acid (vitamin C), carotene (as vitamin A), nicotinic acid, riboflavin, thiamine, sugars (60-80%). Besides sucrose and invert sugars, rhamnose, xylose, ara- binose, ribose, galactose and galac- turonic acid have been identified in the fruit. Invert sugar predominates in the soft dates; sucrose in dry varieties. The dried date, used in Ayurvedic and Unani compositions, contains protein 2.5-3, fat 0.5, carbohydrates 75.882.9% and calcium 35.9, phosphorus 129.3 and iron 3.4 mg/100 g. Presence of sterols of ergosterol group, and esterone has been reported from dried date seeds.

Charged C-glycosylflavones and caf- feylshikimic acid, leucocyanidin are characteristically present in the plant. Flavonol glycosides are also common. Several uncharged C-glycosylflavones were also detected.

Dosage: Fresh fruit—10-50 g, dried fruit—10-15 g. (API, Vol. IV.)... phoenix dactylifera

Phoenix Paludosa

Roxb.

Family: Palmae.

Habitat: Coastal swamps of West Bengal (particularly Sundarbans), Orissa and the Andamans.

Ayurvedic: Hintala.

Folk: Hital (Orissa), Hintalamu (Telugu).

Action: Fruits—antiphlogistic, cooling; used in flatulence.

Triacontanol, beta-sitosterol have been isolated from the plant.... phoenix paludosa

Phoenix Pusilla

Gaertn.

Family: Palmae; Arecaceae.

Habitat: Coromandel Coast.

Ayurvedic: Parushaka (Kerala). (Grewia Asiatica Linn., Tiliaceae, Is Also Equated With Parushaka.)

Siddha/Tamil: Kalangu, Ithi, Sagi.

Action: Fruit—Cooling, Laxative. Used In Respiratory Disorders. Gum—Used In Diarrhoea And Genitourinary Diseases. Fresh Sap— Laxative.... phoenix pusilla

Phoenix Sylvestris

Roxb.

Family: Palmae; Arecaceae.

Habitat: Andhra Pradesh, Karnata- ka and Madhya Pradesh.

English: Wild Date Palm.

Ayurvedic: Kharjuuri.

Siddha/Tamil: Periyaitcham, Icham.

Folk: Sulemaani Khajuur, Desi Khajuur.

Action: Fruits—restorative. Juice— cooling, gastric stimulant. Seeds— used in ague. Root—used for nervous debility.

Fresh, unfermented sap (Niraa) is a good source of ascorbic acid, nicotinic and isonicotinic acids, riboflavin, thiamine, sugars; crystine, leucine, isoleucine, lysine, phenylalanine, thre- onine, tyrosine.

The concentration of amino acids is much higher in palm jaggery than in sugar cane jaggery.

Fresh fruits contain protein 1.2, fat 0.4, calcium 0.022 and phosphorus 0.38%.

Dosage: Fruit—10-20 g paste. (CCRAS.)... phoenix sylvestris

Pholidota Articulata

Lindl.

Ayurvedic: Jivanti (substitute). (Dendrobium macraei Lindl. is also used as a substitute for Jivanti. Jivanti is equated with Leptadenia reticulata W. & A.)

Action: Age-sustaining tonic, restorative.... pholidota articulata

Phonocardiograph

An instrument for the graphic recording of heart sounds and murmurs.... phonocardiograph

Phonsa

(American) Filled with joy Phonsah, Phonsia, Phonsiah, Phonsea, Phonseah, Phonza, Phonzia, Phonzea... phonsa

Phospholipids

Fats containing phosphorous, and, along with cholesterol, the primary constituents of cell membranes.... phospholipids

Phosphorus Burns

Phosphorus compounds are used in chemical laboratories, some industrial processes, matches, ?reworks and in certain types of aerial bombs and artillery shells. If particles of phosphorus settle on or become embedded in the skin, the resulting burn should be treated with a 2 per cent solution of sodium bicarbonate, followed by application of a 1 per cent solution of copper sulphate.... phosphorus burns

Photina

(American) A stylish woman Photeena, Photeana, Photiena, Photeina, Photyna... photina

Photodermatoses

Diseases of the SKIN for which sunlight is partially or wholly responsible. In su?cient dosage, short-wave ultraviolet light (UVB – see ULTRAVIOLET RAYS (UVR)) always causes ERYTHEMA. Higher doses progressively cause OEDEMA and blistering; this is acute sunburn. Graduated exposure to UVB causes pigmentation (tanning). Prolonged chronic exposure to sunlight eventually accelerates ageing of the exposed skin with LENTIGO formation and loss of COLLAGEN and elastic tissue. After decades of such exposure, epidermal DYSPLASIA and CANCER may supervene.

Drugs given orally or topically may induce phototoxic reactions of various types. Thus, TETRACYCLINES exaggerate sunburn reactions. and the diuretic FRUSEMIDE may cause blistering reactions. Psoralens induce erythema and pigmentation. AMIODARONE also induces pigmentation. (See also PHOTOCHEMOTHERAPY.)

Phytophotodermatitis is a streaky, blistering photodermatosis typically seen on the limbs of children playing in grassy meadows in summer. The phototoxic reaction is caused by psoralens in weeds.

Berlocque dermatitis is a pattern of streaky pigmentation usually seen on women’s necks, caused by a reaction to psoralens in perfumes.

Certain rare metabolic diseases may lead to photosensitisation. They include the PORPHYRIAS and PELLAGRA. Other skin diseases such as lupus erythematosus (see under LUPUS) and ROSACEA may be aggravated by light exposure. Sometimes, in the absence of any of these factors, some people spontaneously develop a sensitivity to light causing various patterns of DERMATITIS or URTICARIA. The most common pattern is ‘polymorphic light eruption’ which typically appears within a day or two of arrival at a sunny holiday destination and persists until departure. Continuously exposed areas, such as the hands and face, may be ‘hardened’ and unaffected.

Treatment Appropriate clothing and headgear, sunscreen creams and lotions are the main preventative measures.... photodermatoses

Photosensitive

Reacting poorly to sunlight, either by skin reactivity or by forming abnormal sunlight-mediated serum metabolites... photosensitive

Phragmites Communis

Trin.

Family: Gramineae; Poaceae.

Habitat: The Himalayas, from Kashmir to Kumaon up to an altitude of 4,000 m.

English: Common Reed.

Folk: Dila, Dambu (Punjab).

Action: Rhizomes and roots—diuretic, emmenagogue, diaphoretic, hypoglycaemic, antiemetic.

The rhizomes are rich in carbohydrates; contain nitrogenous substances 5.2, fat 0.9, N-free extr. 50.8, crude fibre 32.0, sucrose 5.1, reducing sugars 1.1, and ash (rich in silica) 5.8%; as- paragine 0.1% is also present. Leaves possess a high ascorbic acid content (200 mg/100 g).Nodes and sheaths yield 6.6% and the underground parts over 13% of furfural.

The root of common Reed is prescribed in Chinese traditional medicine as an antipyretic against influenza and fevers. Presence of polyols, betaines and free poline has been reported in the methanolic extract. The extract is reported to show bactericidal activity. The root gave a polysaccha- ride which contains sugars, arabinose, xylose and glucose in a molar ratio of 10:19:94; some ofthe fractions showed immunological activity.... phragmites communis

Phylicia

(Greek) One who is fortunate Phyliciah, Phylicea, Phyliceah, Phylecia, Phylecea, Phyleciah, Phyleceah... phylicia

Phyllanthus Maderaspatensis

Linn.

Family: Euphorbiaceae.

Habitat: Throughout drier parts of India.

Unani: Kanochaa, Isfahaan Marv.

Siddha/Tamil: Mela-nelli.

Action: Leaves—an infusion is used in headache. Seeds—carminative, diuretic.

Whole plant revealed antispasmod- ic action in isolated guinea-pig ileum, CNS depressant and hypothermic effects in mice.... phyllanthus maderaspatensis

Phragmites Karka

Trin. ex Steud.

Synonym: P. roxburghii (Kunth) Steud.

P. maxima Blatter & McCann in Part.

Family: Gramineae; Poaceae.

Habitat: Throughout India, in marshy places.

English: Common Reed-grass.

Ayurvedic: Nala. (Arundo donax Linn. is also equated with Nala.)

Siddha/Tamil: Perunanal.

Folk: Narakul.

Action: Stem and rhizome— diuretic, diaphoretic. Used topically to relieve insect bite.

P. karka is not discriminated from P communis for medicinal uses in Indian medicine.... phragmites karka

Phyla Nodiflora

(L.) E. Greene.

Synonym: Lippia nodiflora A. Rich.

Family: Verbenaceae.

Habitat: Throughout India, near fresh water bodies.

English: Jalapippali, Shaaradi, Shakulaadani, Matsyagandhaa, Matsyaadani, Laangali, Vashiraa.

Siddha/Tamil: Poduthalai.

Action: Spasmolytic, diuretic, febrifuge.

The plant contains flavone glyco- sides—nodiflorins A and B, lipiflorins A and B, as well as free flavones including 6-hydroxyluteolin, nepetin and nodifloretin along with beta-sitosterol and stigmasterol glucosides.

Dosage: Plant—10-20 ml. juice. (CCRAS.)... phyla nodiflora

Phyllanthus Amarus

Schum. & Thonn. Phyllanthus fraternus Webster.

Family: Euphorbiaceae.

Habitat: Throughout the hotter parts of India, particularly on cultivated land, up to 1,000 m.

Ayurvedic: Bhuumyaamalaki, Bahu- patri, Bhuudhaatri, Bahuphalaa, Taamalaki.

Unani: Bhui Aaamalaa.

Siddha/Tamil: Keelkaay Nelli.

Action: Plant—diuretic, deobstru- ent, astringent, anti-inflammatory, styptic. Used as a single drug in the treatment of jaundice. Used in prescriptions for dyspepsia, indigestion, chronic dysentery, urinary tract diseases, diabetes, skin eruptions.

The leaves yielded lignans—phyl- lanthin (bitter), hypophyllanthin (nonbitter); niranthin, nirtetralin and phyl- tetralin. The whole plant gave a number of flavonoids, including quercetin, quercitrin, astragalin, rutin, kaempfer- ol. Isolation of a hydrolysable tannins, amarulone, is reported from the plant.

The plant is reported to show antiviral activity against hepatitis B virus and related hepadna virus. It was also found to effectively repair CCl4-induced liver damage in rats.

The herb exhibited hypotensive and hypoglycaemic activity. (Indian J Exp Biol 1995, 33 (11) 861-864.)

Phyllanthus fraternus Webster: The ethanolic extract of the plant exhibited hepatotoxic-protective activity in albino rats pretreated with CCl-4, The petroleum extract is reported to possess analgesic and anti-inflammatory properties. The flavonoids, isolated from the ethanolic extract of the plant, exhibit hypoglycaemic activity in alloxan-treated albino rats. The ethanolic and aqueous extracts of the plant exhibit antibacterial and antifun- gal activity.

Dosage: Root, stem, leaf—3-6. powder. (API, Vol. I and III.)... phyllanthus amarus

Phyllanthus Distichus

Muell.-Arg.

Synonym: P. acidus Skeels. Cicca acida (Linn.) Merrill.

Family: Euphorbiaceae.

Habitat: Indian gardens.

English: Country Gooseberry.

Ayurvedic: Lavali-phala, Lowani Hariphala.

Siddha/Tamil: Aranelli.

Action: Fruit—astringent, tonic to liver; improves appetite, useful in biliousness, constipation, vomiting, bronchitis. Roots and seed— cathartic. The juice of the root bark produces headache and severe abdominal pain.

The root bark contains 18% tannin, saponin, gallic acid and a crystalline substance (probably lupeol). The bark contains beta-amyrin and phyllanthol.

The fruit is sour; contains acidity (as acetic acid) 1.70%.... phyllanthus distichus

Phyllis

(Greek) Of the foliage; in mythology, a girl who was turned into an almond tree Phylis, Phillis, Philis, Phylys, Phyllida, Phylida, Phillida, Philida, Phyllina, Phylina, Phyliss... phyllis

Phylum

The taxonomic group below a Kingdom, and above a Class. See Taxonomy.... phylum

Phyre

(Armenian) One who burns brightly Phyra, Phyria, Phyrea... phyre

Physical Activity

Any form of exercise or movement.... physical activity

Phyllanthus Niruri

Linn.

Family: Euphorbiaceae.

Habitat: Native to America.

English: Chanca Piedra.

Ayurvedic: Bhuumyaamalaki, assigned to P. niruri, has now been equated with P.fraternus.

Action: Antispasmodic, antipyretic, diuretic, antiviral, bactericidal.

Taking Chanca Piedra orally does not seem to be effective for treating hepatitis B. The herb contains niuride, which inhibits specific HIV-protein binding activity, but does not protect cells from acute HIV infection. (Natural Medicines Comprehensive Database, 2007.)... phyllanthus niruri

Phyllanthus Simplex

Retz.

Synonym: P. virgatus J. R. et G. Forst.

Family: Euphorbiaceae.

Habitat: Throughout India.

Ayurvedic: Bhumyaamalaki (var.).

Folk: Mothi-bhuiaamvali (Maharashtra).

Plant—antiseptic. Fresh leaves, bruised in butter milk, are used as a wash for itch. Fresh leaves, flowers and fruits with cumin seeds and sugar, are used in gonorrhoea. Root—applied to mammary abscesses. Fruits contain oxalic acid.... phyllanthus simplex

Phyllanthus Urinaria

Linn.

Family: Euphorbiaceae.

Habitat: Throughout the plains of India from Punjab to Assam and Southward to Kerala up to 1,000 m.

Ayurvedic: Bhuumyaamataki (var.), Taamravalli.

Siddha/Tamil: Senkeezhnelli.

Folk: Laal-bhui-aamlaa, Hazaar- mani.

Action: See P. amarus.

The leaf and stem gave flavonoids— quercetin, astragalin, quercitrin, iso- quercitrin and rutin; Me-brevifolin- carboxylate and tri-dehydrochebulic acid.... phyllanthus urinaria

Physalia

A siphonophore or hydrozoan colony that is usually regarded as a jellyfish by non-biological people. It has a float, rather than a bell, and the tentacle(s) hang beneath. There are two main varieties: 1. Physalia utriculus. A single-tentacled species common in the warmer waters of the world, and especially common on the eastern seaboard of Australia where it causes some 10,000-odd stings each summer. No deaths have ever been reported, and usually it causes mild-to moderate skin pain and possibly some aching pains in the draining lymph glands in the leg or armpit. 2. Physalia physalis. The multi-tentacled species found world-wide, but commonly on both side of the North Atlantic. Stings are common on the eastern coast of the United States and have now caused 3 deaths as well as manysevere systemic symptoms. Specimens may have a float length of up to 25cm with tentacles up to 30m in length. Some severe systemic symptoms resemble a modified Irukandji syndrome with painful breathing, muscle cramps, anxietyand sweating.... physalia

Physalis Alkekengi

Linn.

Family: Solanaceae.

Habitat: Native to South-east Europe and Japan; naturalized in many parts of the world; grown in Indian gardens.

English: Strawberry Tomato, Winter Cherry. ( Withania somnifera is also known as Winter Cherry.)

Ayurvedic: Raajaputrikaa.

Unani: Kaaknaj.

Action: Berries—diuretic, antitussive, oxytocic, analgesic, febrifuge; used for urinary disorders, suppression of urine, gout and intermittent fevers.

Berries contain flavonoids, including luteolin-7-glucoside and withas- teroids.... physalis alkekengi

Physalis Angulata

Linn.

Family: Solanaceae.

Habitat: Native to tropical America; cultivated in Indian gardens in Uttar Pradesh and Tamil Nadu; also grows in moist places as a weed.

Action: Plant—diuretic.

salin B and F have been isolated from the ethanolic extract of the whole plant. Both physalin B and F are reported to inhibit the growth of several human leukaemia cell systems.

Aerial parts yielded seco-withano- lides—cleaved steroidal constituents containing physalins. In Taiwan, phy-

Family: Solanaceae.

Habitat: Throughout India, ascending up to 2,300 m.

English: Sun-berry.

Ayurvedic: Tankaari, Parpotikaa, Chirapotikaa.

Siddha/Tamil: Sodakku thakkali.

Action: Berries—diuretic, aperient, alterative. Used for gout and urinary diseases.

Quercetin 3-O-galactoside, isolated from the crude extract of the leaves, is reported to exhibit anti-inflammatory activity comparable to phenylbutazone in carageenan-induced rat paw oedema.

Physalis minima Linn. var indica C. B. Clarke is common weed in irrigated fields and bunds.

The plant contains withasteroids, physalindicanols, withaminimin and withaphysalin, 3-O-glucosides of kaempferol and quercetin, in addition to beta-sitosterol and its glucoside.

The diuretic action of Physalis minima leaves is attributed to the high content of potassium nitrate (8-10%).... physalis angulata

Physical Therapy / Physiotherapy

1 Treatment of pain, disease or injury by physical means. 2 The profession concerned with promotion of health; prevention of physical disabilities; evaluation and rehabilitation of persons disabled by pain, disease or injury; and with treatment by physical therapeutic measures, as opposed to medical, surgical or radiologic measures.... physical therapy / physiotherapy

Physalis Peruviana

Linn.

Habitat: Native to tropical America; grown in the hills and plains throughout India.

English: Cape Gooseberry.

Ayurvedic: Parpoti (var.).

Siddha/Tamil: Perungunni, Potti- pallam.

Folk: Rasbhari, Mako.

Action: Plant—diuretic. Leaf— anthelmintic, an infusion is used in abdominal disorders. Fruits— a good source of carotene and ascorbic acid; eaten as a table fruit.

The fruit contain carotene (as vitamin A) 2,380 IU, thiamine 0.05, ri- boflavin 0.02, nicotinic acid 0.3 and ascorbic acid 49 mg/100 g; mineral matter 0.8%; phytin phosphorus 18, iron 2.0, ionizable iron 0.9, sodium 0.9, potassium 320, copper 0.19, and sulphur 43 mg/100 g. The juice from the ripe fruits contain considerable quantity of pectin. The chief acid is citric acid, but malic and tartaric acids are also present.

The plant is a source of highly oxygenated ergostane-type of steroids— withanolides and related compounds.... physalis peruviana

Physician Assistant

A health care professional who provides patient services ranging from taking medical histories and doing physical examinations to performing minor surgical procedures. Physicians’ assistants work under the supervision of a physician.... physician assistant

Physician-assisted Suicide

See SUICIDE.... physician-assisted suicide

Physochlaina Praealta

Miers.

Family: Solanaceae.

Habitat: Lahul valley (Punjab), Ladakh, North Kashmir. Western Tibbet at altitudes of3,300-4,600 m.

Folk: Daturaa (Ladakh), Laangtaan; Sholar, Bajarbang (Punjab).

Action: Leaves—poisonous and narcotic.

The roots of the plant contain 0.64% alkaloids (calculated as hyoscyamine). The plant constitutes an excellent source of atropine.... physochlaina praealta

Phythisis

Any wasting disease in which the whole body or part of the body is involved... phythisis

Phytosterols

Plant lipids, with little other than dietary value, but often excitedly referred to as “Hormone Precursors” with incorrect but well-meaning pseudo­science. See: STEROIDS, PLANT... phytosterols

Picorna Viruses

These infectious agents derive their name from pico (small) and from RNA (because they contain ribonuleic acid). They are a group of viruses which includes the ENTEROVIRUSES and the RHINOVIRUSES.... picorna viruses

Piedad

(Spanish) A devout woman Piedade, Piedadd, Pyedad... piedad

Pierina

(Greek) One who is dependable Pierinah, Piereena, Piereenah, Piereana, Piereanah, Pieryna, Pierynah... pierina

Picea Smithiana

Boiss.

Synonym: P. morinda Link. Abies smithiana Lindl.

Family: Pinaceae.

Habitat: The Himalayas from Kashmir to Kumaon at altitudes of 1,500-3,500 m.

English: West Himalayan Spruce.

Folk: Roi, Rhai, Raghaa, Kathela, Kandre, Morindaa. Spruce (trade).

Action: Essential oil—antiseptic. Used in bath salts, room sprays and deodorants.

Key applications ? Fir Needle Oil, obtained from Picea abies, synonym P. excelsa)—externally and internally, for catarrhal illness of the upper and lower respiratory tract; externally, for rheumatic and neuralgic pains. (German Commission E.)

The oil contains alpha-pinene, l- alpha-phellandrene, dipentene, bornyl- acetate, cadinene, S-guaiazulene and a bicyclic sesquiterpene. The oil distilled from the leaves collected in Gul- marg had a ester content of 23.2% (as bornyl acetate). The bark contained 4.22% tannin.

Picea abies has been introduced at Manali (at 1,890 m). It yields an ole- oresin which is used in plasters and ointments. The essential oil is used in... picea smithiana

Picrasma Quassioides

Bennett.

Family: Simaroubaceae.

Habitat: Garhwal, Himachal Pradesh and Kulu.

English: Quassia (substitute for P excelsa Lindtl).

Ayurvedic: Bhurangi, Nimbi. (Clerodendrum serratum and its related species represent Bhaargi or Bhaarangi.)

Folk: Nimatotaa.

Action: Wood—a non-astringent bitter tonic and stomachic, amoe- bicidal, anthelmintic (used as enema), insect repellent. Used as a supporting medicine for temporary relief in cirrhosis of liver.

Many indole alkaloids of beta-car- boline, canthin-6-one and beta-carbo- line dimer type, have been isolated from the wood. These are reported to increase the blood flow rate in the intestine and stomach of rabbit; also exhibited antiviral activity on Herpes simplex virus.

Nigaki lactone and methylnigaki- none, isolated from the wood, showed antigastric ulcer activity in rats. The extract of the wood is reported to prevent the secretion of gastric juice in a dose-dependent manner in rats. The extract also showed the same effects on rats having aspirin-induced gastric ulcer.

Family: Scrophulariaceae.

Habitat: The alpine Himalayas from Kashmir to Sikkim.

English: Picrorhiza.

Ayurvedic: Katukaa, Katurohini, Kattarohini, Katuki, Katukikaa, Krishnabhedaa, Kaandaruhaa, Matsyashakalaa, Chakraangi, Shat- parvaa, Arishta, Ashokarohinya, Shakuldaani.

Unani: Kutki, Kharbaq-e-Hindi.

Siddha/Tamil: Kaduguragini.

Action: Root—stomachic, antidiar- rhoeal, cholagogue, hepatoprotec- tive. Used in hepatitis, chronic dysentery, amoebiasis.

Key application: In jaundice, intermittent fever, dyspnoea and skin diseases. (The Ayurvedic Pharmacopoeia ofIndia.)

The roots yield a glycosidal bitter principle, kutkin, found to be a mixture of two iridoid glycosides, picro- side I and kutkoside. Also obtained were D-mannitol, kutkiol, kutkisterol and a ketone (identical with apocynin).

Kutkin exhibited hepatoprotective activity in CCl4-induced toxic rats.

Picroliv, a standardized fraction from the alcoholic extract of the root and rhizome, containing 55-60% of a mixture of picroside I and kutkoside (1:15) showed dose-dependent protective activity on isolated hepatocytes in vitro against thiocetamide-induced hepatic damage in rat and was found to be more potent than Silymarin, a known hepatoprotective agent. Pi- croliv is reported to show protective effect against rifampicin-induced hep- atotoxicity in rats. It also exerts hy- polipidaemic effect in normal, triton- treated and cholesterol-fed rats.

Kutkin, picroside I and kutkoside exhibit anti-inflammatory property.

The phenolic glycoside, androsin, isolated from the plant, prevents allergen and platelet activating factor- induced bronchial obstruction in guinea-pigs in vitro.

Cucurbitacin glycosides, isolated from the root, exhibit liver protective, tumour inhibitory and anti-inflammatory activity.

Dosage: Root—1-3 g; 3-6 g as purgative. (CCRAS.)... picrasma quassioides

Pigeon Breast

See CHEST, DEFORMITIES OF.... pigeon breast

Pigeon Pea

See Guandul.... pigeon pea

Pilar

(Spanish) Resembling a pillar; having great strength Pilarre, Pylar, Pylarre... pilar

Pilialoha

(Hawaiian) One who is dearly loved... pilialoha

Pililani

(Hawaiian) Having great strength Pililanie, Pililany, Pililaney, Pililanee, Pililanea... pililani

Pilisi

(Hawaiian) Living the simple life Pilisie, Pilisy, Pilisey, Pilisee, Pilisea... pilisi

Pills

Small round masses containing active drugs held together by syrup, gum, glycerin, or adhesive vegetable extracts. They are sometimes without coating, being merely rolled in French chalk, but often they are covered with sugar or gelatin. Many people use the term interchangeably with tablets, and ‘the pill’ has come to represent oral contraceptives.... pills

Picrorhiza Scrophulariaeflora

Pennell.

Family: Scrophulariaceae.

Habitat: Eastern Himalayan in Nepal and Sikkim.

Action: Properties similar to those of Picrorhiza kurroa.

The root contains the iridoid glyco- sides, amphicoside, catalpol, aucubin and androsin; also cucurbitacin glyco- sides.

Action: Stimulant (excites most glands), expectorant, powerful diaphoretic. Used in hair tonics to stimulate hair growth. (Irritates stomach and causes vomiting in overdose.)

The leaf contains a parasympathetic stimulant pilocarpine (0.5%). It is an obsolete medicinal herb, but is used in the production of pilocarpine. (Natural Medicines Comprehensive Database, 2007.)... picrorhiza scrophulariaeflora

Picture Archiving And Communications System (pacs)

The use of digital imaging systems to replace conventional X-ray pictures and other imaging techniques. Though expensive to operate, digital imaging and storage systems o?er promising possibilities for transmission of clinical images within and between hospitals and community health-care units, providing fast access and remote working that will bene?t patients and health-care sta? alike. When security and con?dentiality are assured, images could be transferred via the Internet and teleradiology. In future, hospitals might be able to eliminate the costly physical transfer and storage of X-ray ?lms. The integration of PACS with hospital information systems in the NHS will (hopefully) facilitate the introduction of electronic radiology.... picture archiving and communications system (pacs)

Pilewort

Ranunculus ficaria. N.O. Ranunculaceae.

Synonym: Lesser Celandine, Little Celandine (not to be confused with Chelidonium majus , q.v.).

Habitat: Moist places, both open and shady.

Features ? Flower stem grows up to six inches (slightly longer than leaf stalk) with two or three leaves, and ending in a single bright yellow, buttercup-like flower, of usually eight petals and three sepals. Numerous leaves from the root on long stalks, glossy, heart-shaped, whitish-green blotches, notched margins. Root characteristically bunched into white, fleshy, club-shaped or oblong-rounded knots.

Part used ? Herb.

Action: Astringent.

Used almost entirely (as the common name denotes) in the treatment of piles. The ounce to pint boiling water infusion is taken consistently in wineglass doses, and an ointment is made by macerating the herb in boiling lard for twenty-four hours. Probably the best of all known remedies for this complaint, the combination with Witch Hazel is found to be particularly effective.... pilewort

Pilocarpus Microphyllus

Stapf.

Family: Rutaceae.

Habitat: Native to tropical America; cultivated in Indian gardens.

Family: Umbelliferae; Apiaceae.

Habitat: Native to the Mediterranean region; cultivated in Uttar Pradesh., Punjab, Assam and Orissa.

English: Anise, Aniseed.

Unani: Anisoon, Baadiyaan-roomi.

Action: Carminative, diuretic, anticholerin, antispasmodic, expectorant. Used for flatulence, dry coughs, whooping cough, bronchitis.

Key application: Internally in dyspeptic complaints; internally and externally in catarrhs of the respiratory tract. (German Commission E, ESCOP, WHO, The British Herbal Pharmacopoeia.)

The fruit gave volatile oil consisting mainly of trans-anethole (70-90%), with estragole, anise ketone, anisic acid, beta-caryophyllene, anisaldehyde, linalool. The fruit contained traces of furocoumarins; seeds gave benzoic acid, caffeic acid, containing protein and myristicin. Roots afforded sterols, coumarins and flavone glyco- sides. Aniseed has been demonstrated to increase the mucociliary transport in vitro and to significantly increase liver-regeneration in rats.

Aniseed is also used as a galacta- gogue. This property is thought due to the presence of polymers of anethole, dianethole and photoanethole.

Aqueous extract of roasted aniseed is reported to show cholinomimetic effect on rat blood pressure, rat jejunum and frog rectus abdominis preparations.

Alcoholic extract of aniseeds possesses antimicrobial and fungicidal activity.

Anethole has a structure similar to catecholamines including adrenaline, noradrenaline and dopamine and to the hallucinogenic compound myris- ticin as well. (Natural Medicines Comprehensive Database, 2007.)... pilocarpus microphyllus

Pilonoidal Sinus

A SINUS that contains hairs, usually occurring in the cleft between the buttocks. It may get infected and cause considerable pain. Treatment is by antibiotics and, if necessary, surgical removal.... pilonoidal sinus

Pilot Study

A small-scale test of the methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.... pilot study

Piluki

(Hawaiian) Resembling a small leaf Pilukie, Piluky, Pilukey, Pilukee, Pilukea... piluki

Pilvi

(Italian) A cheerful woman Pilvie, Pilvee, Pilvea, Pilvy, Pilvey... pilvi

Pimento

Love... pimento

Pimenta Dioica

(Linn.) Merrill.

Synonym: P. officinalis Lindl.

Family: Myrtaceae.

Habitat: Native to West Indies and tropical America; grown in Indian gardens; in Bengal, Bihar, Orissa and Bangalore.

English: Allspice tree, Jamaica Pepper tree, Pimento tree.

Action: Berry oil and leaf oil— carminative and stimulant. The oil contains chiefly eugenol (65-80%), responsible for the herb's effect on the digestive system and its pain relief properties; also for anaesthetic effect when crushed berries are applied topically.... pimenta dioica

Pimpernel

Protection, Health... pimpernel

Pimpernel, Scarlet

Anagallis arvensis. N.O. Primulaceae.

Synonym: Poor Man's Weatherglass, Shepherd's Barometer (these names because the flowers close some hours before rain). Red Pimpernel.

Habitat: Cornfields, waste places and in gardens.

Features ? Stem square, weak, much branched, trailing with tendency to ascend, between six inches and one foot long. Leaves small, opposite, ovoid, sessile, entire at edges, black dots underneath. Flowers scarlet, corolla rotate, on long, slender, axillary stalk.

Part used ? Leaves.

Action: Diuretic, hepatic, diaphoretic.

The properties of this herb, although very active, are not yet fully known, and care should be exercised in using it. It has been successful in the treatment of liver irregularities, forms of rheumatism and dropsy. The pulverised leaves are administered in doses of from 15 to 60 grains.... pimpernel, scarlet

Pimpinella Saxifraga

Linn. var. dissectifolia C. B. Clarke, non-Boiss.

Family: Umbelliferae; Apiaceae.

Habitat: Kashmir at 3,900 m.

English: Burnet Saxifrage, Pimpinel- la Root.

Action: Root—carminative, stimulant, expectorant, cholagogue, diuretic, emmenagogue. Used for diarrhoea.

Key application: Rhizome—in catarrhs of the upper respiratory tract. (German Commission E. Above ground parts have been included among unapproved herbs.)

The main components of the fruits and roots are isoeugenol epoxy tiglic ester, isoeugenol epoxy-2-methylbu- tanoic ester and 4-phenyl tiglic ester. Roots also contain pimpinellin and isopimpinellin.... pimpinella saxifraga

Pimples

Technically known as papules, these are small, raised and in?amed areas on the SKIN. On the face, the most common cause is ACNE. BOILS (FURUNCULOSIS) start as hard pimples. The eruption of SMALLPOX and that of CHICKENPOX begin also with pimples. (See also SKIN, DISEASES OF.)... pimples

Piña

Pineapple (Ananas comosus).

Plant Part Used: Fruit, fruit rind.

Dominican Medicinal Uses: Fruit: juice, taken orally as a diuretic for urinary tract or kidney disorders, cleansing the body internally, for treating bacterial infection, cancer, high blood pressure, high cholesterol, menopausal hot flashes; fruit rind: fermented in sugar and water for internally cleansing and refreshing the body.

Safety: Commonly consumed as food; relatively nontoxic; repeated exposure can cause hypersensitivity.

Contraindications: Caution advised during pregnancy due to possible abortifacient effects of plant steroids.

Drug Interactions: For bromelain (protease enzymes from stem): antibiotics, tetracyclines (elevated drug serum levels), anticoagulants and thrombocyte aggregation inhibitors (increased bleeding).

Laboratory & Preclinical Data: In vivo: antidiabetic, antioxidant, antidyslipidemic (ethanolic leaf extract); antifertility (unripe fruit juice); burn debridement (bromelain—stem enzymes); diuretic (root extract).

In vitro: antitumor (bromelain—stem enzymes).

* See entry for Piña in “Part 3: Dominican Medicinal Plant Profiles” of this book for more information, including references.... piña

Pincushion Cactus

Mammilaria species

Description: Members of this cactus group are round, short, barrel-shaped, and without leaves. Sharp spines cover the entire plant.

Habitat and Distribution: These cacti are found throughout much of the desert regions of the western United States and parts of Central America.

Edible Parts: They are a good source of water in the desert.... pincushion cactus

Pineki

(Hawaiian) Resembling a peanut Pinekie, Pineky, Pinekey, Pinekee, Pinekea... pineki

Ping

(Chinese) One who is peaceful Pyng... ping

Pinga

(Inuit) In mythology, goddess of the hunt, fertility, and healing Pingah, Pyngah, Pyngah... pinga

Pingjarje

(Native American) Resembling a young doe

Pingjarji, Pingjarjie, Pingjarjy, Pingjarjey, Pingjarjee, Pingjarjea... pingjarje

Pink

(American) One who is healthy Pinke, Pinka, Pinki, Pinkie, Pinky, Pinkey, Pinkee, Pinkea... pink

Pinkroot

Spigelia marilandica. N.O. Loganiaceae.

Synonym: Carolina Pink, Indian Pink, Maryland Pink, Worm-grass.

Habitat: Southern states of U.S.A

Features ? Imported root is rather less than a quarter of an inch thick, cup-shaped scars on upper surface, many rootlets underneath.

Part used ? Root.

Action: Anthelmintic.

Widely used throughout the United States, where it is considered the best of the vermifuges, and is given to both children and adults suffering from the pests. A purgative such as Senna is usually added, as it is said to cause the Spigelia to act more quickly and effectively. An infusion of 1 ounce to

1 pint is given night and morning, in doses varying with the patient's age up to one teacupful for adults.

In this country such remedies as Tansy and Wormwood are more commonly prescribed in the treatment of worms.... pinkroot

Pinnae

The leaflets or primary division of a pinnate leaf.... pinnae

Pinnatifid

A leaf that is pinnately cleft, but into lobes that do not reach the midrib, and not into separate leaflets.... pinnatifid

Pinnule

A division of a pinna.... pinnule

Pinquana

(Native American) Having a pleasant fragrance

Pinquan, Pinquann, Pinquanne, Pinquanna, Pinquane... pinquana

Pint

A measure of quantity containing 16 ?uid ounces (wine measure) or 20 ?uid ounces (Imperial measure). The metric equivalent is 568 millilitres. (See APPENDIX 6: MEASUREMENTS IN MEDICINE.)... pint

Pinus Excelsa

Wall. ex D. Don.

Synonym: P. wallichiana A. B. Jackson.

Family: Pinaceae.

Habitat: Himalayas from Kashmir to Bhutan at 1,800-3,700 m, also Assam.

English: Indian Blue Pine, Bhutan Pine, Five-leaved Pine.

Ayurvedic: Sarala (var.). Folk: Chillaa.

Action: Uses similar to Pinus roxburghii.

The essential oil contains alpha-and beta-pinene as major constituents.... pinus excelsa

Pinus Succinifera

(Goppert) Cornw.

Family: Pinaceae.

Habitat: Native of northern scandinavia.

English: Baltic Amber, Succinite.

Unani: Ambar, Kahruubaa,

Action: Cardiac tonic, styptic. Vateria indica is used in Unani medicine as a substitute for P succinifera gum-resin (Fossil-resin).... pinus succinifera

Pinworms

Also Threadworm, this is a widespread parasitic nematode, usually benign, but having a rural, white trash, skanky stigma. It mates and reproduces in the intestines of several mammals (including us) and the female exits the anus, usually at night, to shed its eggs and expire. The eggs become like dust motes, kids and puppies scratch their butts, the eggs spread into other mammals, until only a thermonuclear device or burning/razing/earth-salting will clear out a heavy infestation. It’s also the only worm likely to be encountered in temperate zones and the high country.... pinworms

Piper

(English) One who plays the flute Pipere, Piperel, Piperell, Piperele, Piperelle, Piperela, Piperella, Pyper, Pypere, Pyperelle, Pyperella... piper

Piper Hamiltonii

C. DC.

Family: Piperaceae.

Habitat: Sikkim, Terai, West Bengal and Khasi hills, up to 900 m.

English: Wild Pepper.

Folk: Jangali Paan.

Action: Carminative and diuretic.

Kadsurin A and isodihydrofuto- quinol B have been isolated from aerial parts.... piper hamiltonii

Pinus Gerardiana

Wall.

Family: Pinaceae.

Habitat: Northwest Himalayas from Garhwal eastwards at altitudes of 1,800-3,000 m.

English: Neosia Pine, Edible Pine, Chilgoza Pine.

Ayurvedic: Nikochaka. Unani: Chilgozaa.

Action: Kernels—stimulant, carminative, expectorant. Oil from seeds—externally used for wounds and ulcers.

The kernels gave protein 15.9, fat 49.9, carbohydrates 21.6 and mineral matter 2.9%. The mineral constituents include calcium 90.8, phosphorus 92.4 and iron 2.4 mg/100 g. Pectin is present to the extent of 1.73% (calculated as calcium pectate). Seed protein on hydrolysis gave amino acids—leucine, iso- leucine, valine, lysine, phenylalanine, tryptophan and methionine. The oil gave glycerides. The essential oil from oleoresin contains alpha-and beta-pi- nene as major constituents; other constituents are sesquiterpenes.... pinus gerardiana

Pinus Khasya

Royle.

Synonym: P. insularis Endl.

Family: Pinaceae.

Habitat: Assam; introduced into hills of North Bengal.

English: Khasi Pine.

Ayurvedic: Sarala var.

Folk: Digsaa (Khasia).

Action: Spasmolytic, antimicrobial. Oleo-resin—considered superior to that of P. roxburghii for turpentine. The bark contains 7-10% of tannin.

The essential oil from oleoresin contains chiefly alpha-pinene. Other constituents are beta-pinene, longifoline and sesquiterpenes. Abetic acid from rosin possesses weak cardiac and spasmolytic activities.... pinus khasya

Pinus Roxburghii

Sarg.

Synonym: P. longifolia Roxb.

Family: Pinaceae.

Habitat: The Western and Eastern Himalayas.

English: Long-leaved Pine, Three- leaved Pine, Chir Pine.

Ayurvedic: Sarala, Pita-vriksha, Surabhidaaruka, Dhuupavriksha, Namasu. Oleo-resin—Shriveshtaka, Ghandh-Birojaa.

Unani: Sanobar-ul-Hindi. Oleoresin—Gandh-Bihrojaa, Qinn, Berzad.

Siddha/Tamil: Simaidevadaru.

Action: Needle, needle oil— decongestant, expectorant, antiseptic. Oil—used in cough and cold remedies, particularly inhalations and in rubefacients for rheumatism and muscle stiffness. Resin— expectorant, antiseptic, antipruritic.

The essential oil from oleoresin contains chiefly alpha-and beta-pinene; carene and longifoline.

Pinus pinaster Ait (Cluster Pine, Maritime Pine) has been successfully grown in Kulu, Manali and Rahini. German Commission E recognized the efficacy of the needle-oil in catarrhal diseases of the upper and lower respiratory tract (internally, as well as externally).

Dosage: Heartwood, root—1-3 g powder. (API, Vol. III.)... pinus roxburghii

Piper Attenuatum

Buch.-Ham. ex Miq.

Synonym: P. bantamense Blume.

Family: Piperaceae.

Habitat: Eastern tropical Himalayas, Assam, Khasi Hills and the Nilgiris.

Siddha/Tamil: Kattumilaaku.

Action: Root—diuretic. Plant— rubefacient; used for muscular pains and headache.

Several aristolactams have been reported from the aerial parts of the plant. Crotepoxide exhibited significant antitumour activity.

Roots contain alkamides including piperine, piperlonguminine and guineensine.... piper attenuatum

Piper Schmidtii

Hook. f.

Family: Piperaceae.

Habitat: Assam, Western Ghats, the Nilgiris and Palni hills above 1,500 m.

English: Nilgiri Pepper.

Action: Carminative.

The neolignan schmiditin, together with lignin galgravin as well as friedelin, beta-sitosterol and its beta- O-glucoside have been isolated from the extract of aerial parts. The extract exhibited antiamoebic activity.... piper schmidtii

Piper Sylvaticum

Roxb.

Habitat: Assam and Bengal.

Ayurvedic: Vana-Pippali.

Folk: Pahaari Peepal.

Action: Fruit—carminative. Aerial parts—diuretic.

The root yielded a lignin, sesamin; amides (including piperine, piperlon- gumine) and beta-sitosterol.... piper sylvaticum

Piper Thomsoni

Hook. f.

Family: Piperaceae.

Habitat: Sikkim, Bengal, Manipur, Khasi and Jaintia hills.

Folk: Jangali Paan.

Action: Root—(macerated in water) diuretic.... piper thomsoni

Piperacillin

A ureidopenicillin with a broad spectrum of antibacterial activity. The drug is active against the serious infective agent Pseudomonas aeruginosa. (See PENICILLIN.)... piperacillin

Pipothiazine

An antipsychotic drug for maintenance treatment of SCHIZOPHRENIA. It is given as a depot injection that lasts four weeks. (See NEUROLEPTICS; MENTAL ILLNESS.)... pipothiazine

Piper Betle

Linn.

Family: Piperaceae.

Habitat: Cultivated in warmer and damper parts of India; Assam, West Bengal, Bihar, Uttar Pradesh, Karnataka, Kerala.

English: Betel pepper.

Ayurvedic: Taambula, Naagvallari, Naagini, Taambulvalli, Saptashiraa, Bhujangalataa.

Unani: Paan, Tambool.

Siddha/Tamil: Vetrilai Nagavalli, Kammaaruvetritai.

Action: Leaf—stimulant, carminative, astringent, antiseptic. Essential oil from leaves—antispasmodic, antiseptic. Used in respiratory catarrhs. Fruit—bechic.

The leaves afforded beta- and gam- ma-sitosterol, hentriacontane, pen- tatriacontane, n-triacontanol, stearic acid and chavicol. The essential oil from leaves contained carvacrol, euge- nol, chavicol, allyl catechol, cineole, estragol, caryophyllene, cardinene, p- cymene and eugenol methyl ether.

Administration of the leaf extract resulted in decreased tumour burden and tumour incidence and a delay in the onset of mammary tumour in Wistar rats.

The alcoholic extract of the leaf stalk is reported to show antispermatogenic and antiandrogenic effect in male albino rats.

The essential oil exhibited hypoten- sive, cardiac as well as respiratory depressant and cardiotonic properties.

The leaf showed antifungal and antibacterial activity. The antiseptic activity is attributed to chavicol.

Dosage: Leaf—10-15 ml juice. (API, Vol. III.)... piper betle

Piper Chaba

Hunter non-Blume.

Synonym: P. retrofractum Vahl. P. officinarum DC.

Family: Piperaceae.

Habitat: Native to Moluccas, cultivated in Indonesia, also in India.

English: Java Long Pepper.

Ayurvedic: Gajapippali (spikes of Scindapsis officinalis, Araceae, are also known as Gajapippali), Chavya, Chavika.

Siddha/Tamil: Chevuyam.

Action: Similar to P. longum and P. nigrum. Fruits—stimulant, carminative; used in haemorrhoidal affections; as a tonic, after- childbirth. Roots—chewed or brewed in decoction for colic, dyspepsia and gastralgia.

Key application: In diseases of the spleen, chlorosis, diseases of the abdomen. colic, worm infestation. (The Ayurvedic Pharmacopoeia of India.)

Java long pepper is similar in composition to black pepper; it contains less piperine and volatile oil (piperine 4.5 and volatile oil 1.5%).

The stem is used as a substitute for Piper longum root. It contains the alkaloids piperine and piplartine. Beta- sitosterol, glycosides, glucose and fructose and mucilage have also been reported. Active principles show muscle relaxant property.... piper chaba

Piper Cubeba

Linn. f.

Family: Piperaceae.

Habitat: Native to Indonesia; cultivated in Assam and Karnataka.

English: Cubeb, Tailed Pepper.

Ayurvedic: Kankola, Kakkola, Kankolaka, Takkola, Koraka, Kolaka, Kashphala, Sheetalchini, Chinoshana.

Unani: Kabaabchini, Habb-ul- uruus.

Siddha/Tamil: Valmilagu.

Action: Fruit—Carminative, diuretic, expectorant. Used for coughs, bronchitis, asthma, urinary tract infections, amoebic dysentery. Stimulates genitourinary mucous surfaces. Oil—antibacterial, used in genitourinary diseases and cystitis.

Key application: In dysuria. (The Ayurvedic Pharmacopoeia of India.)

The ground fruits have been found to be effective in treating amoebic dys- tentery.

The oil exhibits antiviral activity in rats and antibacterial in vitro.

Unripe fruit contains volatile oil (1020%) consisting of sesquiterpene hydrocarbons; lignans, mainly cubebine (about 2%), with (-)-cubebinin and ki- nokinin; cubebic acid. The oxygenated cyclohexanes, piperenol A and B, together with (+)-crotepoxide and (+)- zeylenol, have been isolated from the fruit. Polyhydroxy cyclohexanes possess antitumour, antileukaemic and antibiotic activities.

Dosage: Fruit—1-2 g powder. (API, Vol. I.)... piper cubeba

Pippi

(French / English) A friend of horses / a blushing young woman Pippie, Pippy, Pippey, Pippee, Pippea... pippi

Pipsissewa

Money, Spirit Calling ... pipsissewa

Pirene

(Greek) Of the sacred well Pireen, Pireene, Piryne, Pirynne, Pireane, Pireane, Pyrene, Pyreen, Pyrean... pirene

Piroplasms

Apicomplexan protozoa of the genus Babesia. Transmitted by Ixodid ticks and cause diseases such as red water fever in cattle and biliary fever in dogs. Rare human infections are recorded, especially in the splenectomised.... piroplasms

Pirouette

(French) A ballet dancer Piroette, Pirouett, Piroett, Piroueta, Piroeta, Pirouetta, Piroetta, Pirouet, Piroet... pirouette

Pisces

(Latin) The twelfth sign of the zodiac; the fishes

Pysces, Piscees, Pyscees, Piscez, Pisceez... pisces

Pisonia Aculeata

Linn.

Family: Nyctaginaceae.

Habitat: The sea coast in Peninsular India, also in the Andaman Islands.

Siddha/Tamil: Karindu.

Folk: Baghachuur (Bengal).

Action: Bark and leaves—counterir- ritant for swellings and rheumatic pains. Fresh leaves—used as a wash for scabies.... pisonia aculeata

Piper Longum

Linn.

Family: Piperaceae.

Habitat: Warmer parts of India, from Central Himalayas to Assam, lower hills of West Bengal; Uttar Pradesh, Andhra Pradesh, Western

Ghats from Konkan southwards to Trivandrum. Often cultivated.

English: Indian Long Pepper, Joborandi.

Ayurvedic: Pippali, Maagadhi, Maagadha, Maagadhaa, Maagad- hikaa, Magadhodbhavaa, Vaidehi, Upkulyaa, Pippalikam, Chapalaa, Kanaa, Krishnaa. Uushnaa, Shaun- di, Kolaa, Tikshna-tandulaa.

Unani: Filfil Daraaz, Daarfilfil.

Siddha/Tamil: Thippili, Arisi thippili. Thippiliver (root).

Action: Fruits—used for diseases of the respiratory tract (cough, bronchitis, asthma); as sedative (in insomnia and epilepsy); as chola- gogue (in obstruction of bile duct and bladder), as emmenagogue, as digestive, appetizer and carminative (in indigestion); as general tonic and haematinic (in anaemia, chronic fevers and for improving intellect). Applied locally on muscular pains and inflammations.

Several aristolactams and dioxoa- porphines have been isolated from Indian long pepper. It also contains the long chain isobutyl amide, longamide, besides guineensine and the lignans, pluviatilol, methyl pluviatilol (farge- sin), sesamin and asarinine.

Piperine is the major alkaloid of peppers.

Piperine is antipyretic, hypotensive, analeptic, CNS stimulant. It has been reported to exert significant protection against CCl4-induced hepatotoxicity in mice. It improves drug availability in experimental animals, and is used for enhancing the efficacy of co- administered medicaments.

Piperine enhanced bioavailability of hexobarbital, phenytoin, propranolol and theophylline. (Sharon M. Herr.) (Piperine is also a component of Piper nigrum.)

N - isobutyl - deca - trans - 2 - trans - 4 - dienamide, isolated from the fruit, exhibited antitubercular property.

Milk extract of the fruit effectively reduced passive cutaneous anaphylaxis in rats. It protected guinea-pigs against antigen-induced bronchospasm.

In China, Piper longum oil constituents were reported to inhibit the increase in serum total cholesterol induced by triton in mice.

The root powder exhibited antifer- tility activity.

A related species, P. peepuloides Roxb., is known as Saamvali Peepal. It is used specifically against obstinate skin diseases and as a sialagogue.

Dosage: Fruit—1-3 mg (API, Vol. IV); root—1-3 g powder. (CCRAS.)... piper longum

Piper Nigrum

Linn.

Family: Piperaceae.

Habitat: Native of the Indo- Malaysian region; cultivated in Western Ghats, Karnataka, Maharashtra, Assam and Kerala.

English: Black Pepper.

Ayurvedic: Maricha, Vellaja, Uushna, Suvrrita, Krishnaa.

Unani: Filfil Siyaah, Safed.

Siddha/Tamil: Milagu. Milaguver (root).

Action: Stimulant, carminative, diuretic, anticholerin, sialagogue, bechic, antiasthmatic. Used in fevers, dyspepsia, flatulence, indigestion, and as mucous membrane and gastro-intestinal stimulant. Externally—rubefacient and stimulant to the skin. Used as a gargle for sore throat. Used with ginger and Piper longum for viral hepatitis.

The fruit yielded piperine, pipera- tine and piperidine; amides, pipery- line, piperoleins A and B, and N-i'so- butyl-cicosa-trans-2-trans-4-dienami- de.

The aqueous extract of roasted black pepper is reported to show cholinomi- metic effect on rat abdominis muscles.

Dosage: Fruit—500 mg to 1 g. (CCRAS.)... piper nigrum

Piper Wallichii

Hand.-Mazz.

Synonym: P aurantiacum Wall ex DC.

Family: Piperaceae.

Habitat: Nepal, Lakhimpur and Khasi Hills in Assam.

Ayurvedic: Wrongly equated with Sambhaaluka. (Sambhaalu has been identified as Vitex negundo.) Renukaa is also a wrong synonym (it is equated with the seed of Vitex agnus-castus).

Siddha/Tamil: Kaattu-milagu.

Action: Fruits—used as uterine stimulant.

The fruit contain piperine, piperet- tine and sylvatine, besides beta-sitos- terol. The seeds gave aurantiamide, its acetate and auranamide.

The fraction, containing alkaloids, showed oxytocic activity. The lignin constituents inhibited platelet aggregation caused by platelet-activating factor.... piper wallichii

Pistachio

Breaking Love Spells... pistachio

Pistillate

A female flower that has pistils but no stamens.... pistillate

Pitana

(American) One who is adorned Pitanna, Pytana, Pytanna, Pitania, Pytania, Pitanea, Pytanea... pitana

Pitarra

(American) An intriguing woman Pitarrah, Pitara, Pitarah... pitarra

Pithasthana

(Hindi) In Hinduism, a name for the wife of Shiva... pithasthana

Pittosporum Dasycaulon

Miq.

Family: Pittosporaceae.

Habitat: The rain forests of South India.

Folk: Gapasundi (Maharashtra), Boogri (Karnataka).

Action: Stem-bark—antibacterial, antifungal.... pittosporum dasycaulon

Pity

(American) A sorrowful woman Piti, Pitie, Pitey, Pitee, Pitea... pity

Pixie

(Celtic) A playful sprite; a fairy or elfin creature

Pixi, Pixy, Pixey, Pixee, Pixea... pixie

Piscidia Piscipula

(Linn.) Sarg.

Synonym: P. erythrina Linn.

Family: Papilionaceae; Fabaceae.

Habitat: Native to America; introduced in India.

English: Jamaica Dogwood.

Action: Sedative, spasmolytic, analgesic, anti-inflammatory.

The bark gave several, isoflavonoids. Piscidone and piscerythrone exhibit spasmolytic activity. Piscidin glycoside and rotenone are toxic constituents.

The bark is used for neuralgia, migraine and insomnia in South America and West Indies.

In some in vitro tests, the root bark's extract exhibited antispasmodic effects as strong as papaverine's (Natural Medicines Comprehensive Database, 2007.)... piscidia piscipula

Pisonia Grandis

R. Br.

Synonym: P. morindaefolia R. Br. ex Wt.

Family: Nyctaginaceae.

Habitat: Cultivated in gardens in Chennai and other places near the sea on both east and west coasts.

English: Lettuce tree.

Siddha/Tamil: Chandi keerai, Leechai kottai keerai, Nachu Kottai keerai.

Action: Fresh leaf—diuretic, used in inflammations (of elephantoid nature in legs and other parts). Root—purgative.

The plant gave octacosanol, beta- sitosterol, alpha-spinasterol, beta-si- tosterol-b eta-D-glucopyranoside, dul- citol and quercetin.

Karkata, Karkataakhya, Kuli- rashringaaya, Kuliravishaanikaa, Vakraa, Vishaani. Ajashringi (also equated with Gymnema sylvestre).

Unani: Kaakraasingi, Kakar.

Siddha/Tamil: Karkatagasingi.

Action: Gall—astringent, expectorant, antiasthmatic, antidysenteric, styptic.

Key application: In cough, bronchitis and dyspnoea. (The Ayurvedic Pharmacopoeia of India.)

The tetracyclic triterpenes, pistaci- gerrimones A, B and C have been isolated from the galls produced on the leaves.

Alpha-pinene 21.8, beta-pinene 16.2, alpha-phellandrene 15.5 and delta-carene 11% are major constituents of the essential oil extracted from galls. The oil is reported to exhibit CNS- depressant, antispasmodic, carminative and antibacterial, antiprotozoal, antiamoebic, anthelmintic activities.

Dosage: Gall—3-6 g powder. (API, Vol. I.)... pisonia grandis

Pistacia Integerrima

Stewart ex Brandis.

Synonym: P. chinensis Bunge subspecies Integerrima (Stewart) Rech. f.

Family: Anacardiaceae.

Habitat: The Himalayas from Indus to Kumaon.

Ayurvedic: Karkatashringi, Shringi, Karkatashringikaa,

Family: Anacardiaceae.

Habitat: Mediterranean countries. The resin is imported into India.

English: Mastic tree.

Unani: Mastagi, Roomi Mastagi, Mastaki.

Siddha/Tamil: Ponnuikan kungi- liyam.

Action: Resin—carminative, diuretic, stimulant, astringent.

The mastic gum contains 2% essential oil. The oil sample from Spain is reported to contain 90% monoterpene hydrocarbons, the major constituents of which are alpha-pinene 79% and my- crene 3%. Chief components ofthe resin triter- penes are mastic acid, isomastic acid, oleanolic acid and tirucallol.

The lyophilized aqueous extract of the aerial parts gave steroid-triterpe- nes, catechin tannins, flavonoids, saponins, resins and sugars. In some regions of Spain, the aerial parts are used against hypertension.

There is some preliminary evidence that Mastic might have hypotensive and antioxidant effects. (The Review of Natural Products by Facts and Comparisons, 1999.)

For prevention of gastric and duodenal ulcers, some researchers thinkMas- tic might have antisecretory and possibly cytoprotective effects. (J Ethno- pharmacol, 15(3), 1986; Natural Medicines Comprehensive Database, 2007.)

Pistacia khinjuk Stocks is known as khinjak, Butum and Roomi Mastagi in Mumbai and Maharashtra. P. tere- binthus Linn. is known as Kabuli Mus- taki.... pistacia integerrima

Placebo Effect

The placebo effect (usually but not necessarily beneficial) is attributable to the expectation that the regimen will have an effect, i.e. the effect is due to the power of suggestion.... placebo effect

Placement

The act of finding a source of care, usually residential.... placement

Pistacia Vera

Linn.

Family: Anacardiaceae.

Habitat: Native to eastern Mediterranean region, Iran, Afghanistan and Central Asian countries; cultivated in North India.

English: Pistachio, Green Almond.

Ayurvedic: Mukuulaka.

Unani: Pistaa (Kernel), Ilk-ul- Ambaat (resin).

Action: The kernel is used as a cardiac and brain tonic; flowers are included in prescriptions for leucorrhoea; husk is used against dysentery and as astringent in stomatitis and tonsillitis.... pistacia vera

Pistia Stratiotes

Linn. var. cuneata Engl.

Family: Araceae.

Habitat: Tropical and sub-tropical Asia, Africa and America.

English: Water Lettuce, Tropical Duckweed.

Ayurvedic: Jalakumbhi, Vaariparni, Vaarimuuli.

Siddha/Tamil: Agasatamarai.

Action: Whole plant and root— diuretic, used for dysuria. Leaf—an- titussive, demulcent, antidysenteric, externally applied to haemorrhoids, ulcers, skin diseases. Ash—applied to ringworm of the scalp.

The plant gave 2-di-C-glycosylfla- vones of vicenin and lucenin type, anthocyanin-cyanidin-3-glucoside, lu- teolin-7-glycoside and mono-C-glyco- sylflavones— vitexin and orientin.

Dosage: Plant—10-20 ml juice. (CCRAS.)... pistia stratiotes

Pithecellobium Dulce

Benth.

Family: Mimosaceae.

Habitat: Cultivated throughout the plains of India.

English: Minila Tamarind, Madras Thorn, Quamachil.

Siddha/Tamil: Karapilly, Kodukkaa Puli.

Folk: Vilaayati Imli, Dakhini Babool.

Action: Bark—astringent, febrifuge, antidysenteric. Stem-bark—spasmolytic. Seeds—anti-inflammatory.

The leaves contain alpha-spinaste- rol; its beta-D-glucoside, octacosanol, kaempferol, its 3-rhamnoside, behenic and lignoceric acids. An insulin-like principle has also been reported in the leaves.

Seeds gave kaempferol, quercetin and a saponin consisting of a mixture of oleanolic and echinocystic acid gly- cosides. Lecithin is also reported from seeds.

The seed exhibited haemolytic agglutinating reaction with human blood. Saponins from seeds show spermicidal activity.

The bark contains tannins (up to 37%) of a catechol type; non-tans 1015%; 1.5% of pectin.... pithecellobium dulce

Pithecellobium Monadelphum

Kosterm.

Synonym: P. bigeminatum auct. non-(L.) Mart. ex Benth.; P. gracile Bedd.

Habitat: Eastern Himalayas, Khasi, Jaintia and Lushai Hills.

Siddha/Tamil: Kalpakku.

Folk: Kachloraa.

Action: Leaf—used externally as a mostrum for leprosy; also applied for promoting growth of hair. Seed—hypoglycaemic. Aerial parts—diuretic, spasmolytic.

The seeds contain 18.3% protein; major amino acids are aspartic acid 13.2, glutamic acid 10.9, alanine 9.7, leucine 8.3, glycine 8.2, serine 7.4%. Seeds contain a poisonous principle pithecolobine. They are used after repeated boiling and discarding of water.... pithecellobium monadelphum

Pittosporum Floribundum

Wight & Arn.

Family: Pittosporaceae.

Habitat: Subtropical Himalayas, Ganjam, Konkan, Western Ghats and the Nilgiris.

Siddha/Tamil: Kattu Sampangi.

Folk: Tumari. Vikhaari, Vekhali (Maharashtra).

Action: Bark—anti-inflammatory, antispasmodic, narcotic; used in chronic bronchitis; also administered in leprous affections; a paste is applied to inflammatory and rheumatic swellings.

The Himalayan plants yielded an essential oil (0.26%) with alpha-pinene, dipentene, linalool, cineol, methyl sal- icylate, decyl aldehyde, anisaldehyde, bergapten, eugenol, indole and salicylic and benzoic acids as major constituents. The oil is applied topically in sprains, bruises, sciatica, rheumatism, chest affections and in certain skin diseases.

The narcotic action of the bark is attributed to the presence of a yellow oleoresin. The bark also contain a saponin, pittosporin.... pittosporum floribundum

Placida

(Italian) Feminine form of Placido; one who is calm; tranquil Placidah, Placyda, Placeda, Placeyda, Placidia, Placidea, Placeeda, Placeada... placida

Plan Of Care

See “care plan”.... plan of care

Planning Ratio

Service provision targets established by an authority on a population basis.... planning ratio

Plantago Amplexicaulis

Cav. var. bauphula (Edgew.) Pilger.

Family: Plantaginaceae.

Habitat: Punjab, Rajasthan and Delhi.

English: Brown Ispaghula.

Unani: Aspaghol.

Action: Seed—astringent. Seed coat—demulcent.

See Plantago ovata.... plantago amplexicaulis

Pituitary

An endocrine gland somewhat behind the eyes and suspended from the front of the brain. The front section, the anterior pituitary, makes and secretes a number of controlling hormones that affect the rate of oxidation; the preference for fats, sugars, or proteins for fuel; the rate of growth and repair in the bones, connective tissue, muscles, and skin; the ebb and flow of steroid hormones from both the gonads and adrenal cortices. It does this through both negative and positive feedback. The hypothalamus controls these functions, secreting its own hormones into a little portal system that feeds into the pituitary, telling the latter what and how much to do. The hypothalamus itself synthesizes the nerve hormones that are stored in the posterior pituitary, which is responsible for squirting them into the blood when the brain directs it to. These neurohormones act quickly, like adrenalin, to constrict blood vessels, limit diuresis in the kidneys, and trigger the complex responses of sexual excitation, milk let­down in nursing, and muscle stimulus in the uterus (birthing, orgasm, and menstrual contractions), prostate, and nipples.... pituitary

Pituitary-linked Disorders

ACROMEGALY or gigantism is the result of the overactivity of, or tumour formation of cells in, the adenohypophysis which produces GROWTH HORMONE (see also PITUITARY GLAND). If this overactivity occurs after growth has ceased, acromegaly arises, in which there is gross overgrowth of the ears, nose, jaws, and hands and feet. DWARFISM may be due to lack of growth hormone.

DIABETES INSIPIDUS, a condition characterised by the passing of a large volume of URINE every day, is due to lack of the antidiuretic hormone (see VASOPRESSIN). Enhanced production of the ADRENOCORTICOTROPHIC HORMONE (ACTH) leads to CUSHING’S SYNDROME. Excessive production of PROLACTIN by micro or macro adenomas (benign tumours) leads to hyperprolactinaemia and consequent AMENORRHOEA and GALACTORRHOEA. Some adenomas do not produce any hormone but cause effects by damaging the pituitary cells and inhibiting their hormone production.

The most sensitive cells to extrinsic pressure are the gonadotrophin-producing cells and the growth-hormone producing cells, so that if the tumour occurs in childhood, growth hormone will be suppressed and growth will slow. Gonadotrophin hormone suppression will prevent the development of puberty and, if the tumour occurs after puberty, will result in amenorrhoea in the female and lack of LIBIDO in both sexes. The thyroid-stimulating hormone cells are the next to suffer and the pressure effects on these cells will result in hypothyroidism (see under THYROID GLAND, DISEASES OF).

Fortunately the ACTH-producing cells are the most resistant to extrinsic pressure and this is teleologically sound as ACTH is the one pituitary hormone that is essential to life. However, these cells can suffer damage from intracellular tumours, and adrenocortical insu?ciency is not uncommon.

Information about these disorders may be obtained from the Pituitary Foundation.... pituitary-linked disorders

Plantar Dermatosis

A common form of eczema (see DERMATITIS) of the soles of the feet typically seen in boys with an atopic (see ATOPY) background who constantly wear trainers.... plantar dermatosis

Plasma Transfusion

This procedure is sometimes used instead of blood TRANSFUSION. PLASMA – the ?uid part of blood from which the cells have been separated

– may be dried and in powder form kept almost inde?nitely; when wanted it is reconstituted by adding sterile distilled water. In powder form it can be transported easily and over long distances. Transfusion of plasma is especially useful in the treatment of SHOCK. One advantage of plasma transfusion is that it is not necessary to carry out testing of blood groups before using it.... plasma transfusion

Plasmid

Any self -replicating genetic component of a cell, e.g. bacteria, which is outside the chromosomes.... plasmid

Plasmids

A generic description of any discrete agents in cells that have genetic functions. They include plasmagenes (self-reproducing copies of a nuclear gene existing outside the cell nucleus) and viruses.... plasmids

Plantago Lanceolata

Linn.

Family: Plantaginaceae.

Habitat: Western Himalayas, from Kashmir to Garhwal and Simla.

English: Rib Grass, Ribwort Plantain, English Plantain, Buckhorn Plantain.

Unani: Baartang, Aspaghol.

Folk: Balatang.

Action: Leaf and root—astringent, bechic, antiasthmatic, anti-inflammatory, hypothermic, diuretic. Seed—cathartic, diuretic, haemostatic.

Key application: Internally, for catarrhs of the respiratory tract and inflammatory alterations of the oral and pharyngeal mucosa; externally for inflammatory reactions of the skin. (German Commission E, ESCOP.)

Globularin and methyl ester of de- sacetyl asperulosidic acid were isolated from the plant along with cat- apol. A crude mucilage, isolated from the leaves, contains L-arabinose 26.0, D-galactose 35.8, D-glucose 21.9, D- mannose 4.6, L-rhamnose 4.6 and uronic acid 6.9%. Alpha-D-glucan was separated from this mucilage.

Leaves gave aucubin and esculetin, in addition to polysaccharides. The whole plant yielded rhamnosidoglyco- side of caffeic acid. Seeds contain 1.1% aucubin. Aucubin exhibits antibacterial activity. Hepatoprotective effect is also attributed to the aucubin content.

Alcoholic extract of young leaves exhibit antibacterial action against Streptococcus betahaemolyticus, Micrococ- cus pyogenes var. aureus and Bacillus subtilis, thus confirming their wound- healing properties.... plantago lanceolata

Plantago Major

Linn.

Family: Plantaginaceae.

Habitat: The temperate and alpine Himalayas from Kashmir to Bhutan at altitudes of 600-3,500 m.

English: Broadleaf Plantain.

Ayurvedic: Ashvagola (var.).

Folk: Isabgol.

Action: Plant—haemostatic, antihistaminic, antibacterial, wound-healing in burns and inflammation of tissues. Leaves— cooling, astringent, diuretic, vulnerary, febrifuge. Used for diarrhoea, bacillary dysentery, hepatitis, urinary diseases, piles, ulcers and skin diseases. Leaves are used for cystitis with blood, haematuria and other bladder disorders.

The aqueous extract of the leaves showed anti-inflammatory activity in mice.

The aerial parts contain an iridoid glucoside, majoroside. The leaves contain a phenylpropanoid glycoside, plantamajoside, exhibiting antibacterial activity against several pathogenic bacteria including E. coli and Staphy- lococcus aureus. (The glycoside is less inhibitory than the free acids, caffeic, ferulic, and rosmarinic and esculetin.)... plantago major

Plantago Ovata

Forsk

Synonym: P. Ispaghula Roxb.

Family: Plantaginaceae.

Habitat: Cultivated In Parts Of Rajasthan And Maharashtra.

English: Ispaghula, Spogel Seeds, Blond Psyllium.

Ayurvedic: Ashvagola. Ashwakarna (Also Equated With Shorea Robusta).

Unani: Aspaghol.

Siddha/Tamil: Isapppa.

Folk: Isabgol.

Action: Seed And Husk—Laxative, Diuretic, Demulcent, Bechic, Cholinergic. Used In Inflammatory Conditions Of The Mucous Membrane Of Gastrointestinal And Genitourinary Tract, Chronic Amoebic And Bacillary Dysentery; Also In Hypercholesterolemia.

Key Application ? In Chronic Constipation And Irritable Bowel. (German Commission E.) Also In Constipation Due To Duodenal Ulcer Or Diverticulitis (Who.) German Commission E Also Noted That Blond Psyllium Seed Lowers Serum Cholesterol Levels. It Has Also Been Shown To Slow Sugar Absorption Thereby Reducing Blood Glucose. (Escop.) Use Of Blond Psyllium Husk Up To Six Months Did Not Clinically Alter Vitamin Or Mineral Status In A Review Of Eight Human Trials. It Did Not Reduce Absorption Of Calcium. (J Am Geriatr Soc, 43, 1995; Am J Clin Nutr, 71, 2000; Natural Medicines Comprehensive Database, 2007.)

The Seed Contains Amino Acids Including Valine, Alanine, Glutamic Acid, Glycine, Cystine, Lysine, Leucine And Tyrosine; And A Mucilage Consisting Of A Mixture Of Polysaccharides Composed Mainly Of Xylose, Arabinose And Galacturonic Acid; Rhamnose And Galactose Are Also Present. The Seeds Also Gave Aucubin, The Antibacterial Principle. The Seed Coat Contains Fatty Acids Mainly Linoleic, Oleic And Palmitic Acids In Decreasing Concentrations.

The Seeds Show A Liver Protective Effect On Induced Hepatotoxicity In Mice. In China, The Plant Is Used Clinically To Treat Certain Types Of Hepatitis (Activity Due To Aucubin Content).

Dosage: Husk—5-10 G. (Ccras.)... plantago ovata

Platelet Aggregation

Platelets are the small, rather uniform fragments of large bone marrow cells that aid the blood in coagulation, hemostasis, inflammation, and thrombus formation. Mild subclotting and sticking is a common early condition that can lead to thrombosis, atherosclerosis, and strokes, and can be helped by an aspirin a day, better fat digestion, and Ceanothus.... platelet aggregation

Platelets

Blood platelets, or thrombocytes, are small spherical bodies in the BLOOD, which play an important part in the process of its COAGULATION. Normally, there are around 300,000 per cubic millimetre of blood.... platelets

Platinum

(English) As precious as the metal Platynum, Platnum, Platie, Plati, Platee, Platy, Platey, Platea... platinum

Platona

(Spanish) A beloved friend Platonia, Platonea, Platonya, Platoniya... platona

Platt

(French) From the plains Platte... platt

Plantain, Broad And Narrow Leaf

Plantago species

Description: The broad leaf plantain has leaves over 2.5 centimeters across that grow close to the ground. The flowers are on a spike that rises from the middle of the cluster of leaves. The narrow leaf plantain has leaves up to 12 centimeters long and 2.5 centimeters wide, covered with hairs. The leaves form a rosette. The flowers are small and inconspicuous.

Habitat and Distribution: Look for these plants in lawns and along roads in the North Temperate Zone. This plant is a common weed throughout much of the world.

Edible Parts: The young tender leaves are edible raw. Older leaves should be cooked. Seeds are edible raw or roasted.

Other Uses: To relieve pain from wounds and sores, wash and soak the entire plant for a short time and apply it to the injured area. To treat diarrhea, drink tea made from 28 grams (1 ounce) of the plant leaves boiled in 0.5 liter of water. The seeds and seed husks act as laxatives.... plantain, broad and narrow leaf

Plasma Exchange

Also known as plasmapheresis. The removal of the circulating PLASMA from the patient. It is done by removing blood from a patient and returning the red cells with a plasma expander. The plasma exchange is carried out through an in-dwelling CANNULA in the femoral vein, and the red cells and plasma are separated by a hemonetics separator. Usually a sequence of three or four sessions is undertaken, at each of which 2–3 litres of plasma are removed. The lost plasma can either be replaced by human serum albumin (see ALBUMINS) or a plasma expander.

In autoimmune disorders, disease is due to damage wrought by circulating ANTIBODIES or sensitised lymphocytes (see LYMPHOCYTE). If the disease is due to circulating humoral antibodies, removal of these antibodies from the body should theoretically relieve the disorder. This is the principle on which plasma exchange was used in the management of autoimmune diseases due to circulating antibodies. Such disorders include Goodpasture’s syndrome, SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) and MYASTHENIA GRAVIS. One of the problems in the use of plasma exchange in the treatment of such diseases is that the body responds to the removal of an antibody from the circulation by enhanced production of that antibody by the immune system. It is therefore necessary to suppress this homeostatic response with cytotoxic drugs such as AZATHIOPRINE. Nevertheless, remissions can be achieved in autoimmune diseases due to circulating antibodies by the process of plasma exchange.... plasma exchange

Platanus Orientalis

Linn.

Family: Platanaceae.

Habitat: Native to eastern Mediterranean region; cultivated in Kashmir and North-western Himalayas at 1,200-2,400 m.

English: Oriental Plane, Oriental Sycamore. European Plane tree.

Folk: Chinaar, Buin (Kashmir and Punjab).

Action: Bark—antidiarrhoeal, antiscorbutic, antirheumatic. Leaf—astringent. Buds—antiseptic, used for urinary infection.

The buds yielded kaempferol, its derivatives and caffeic acid. The me- thanolic extract exhibits antiseptic and antimicrobial activities.

The bark contains 1.5% of platanin, also 5.9% tannin and 7.3% non-tans. The shoots and leaves contain alan- toin; roots phlobaphene. The sap of the tree contains up to 90% mannitol. A triterpene, platanolic acid, is found in most parts of the plant except the fruit.... platanus orientalis

Platycodon Grandiflorum

(Jacq.) A. DC.

Family: Campanulaceae.

Habitat: East Asia; introduced into India and cultivated in rockeries and borders.

English: Balloon Flower, Chinese Bell Flower.

Action: Expectorant and antitussive. Root—used to treat cough, tonsillitis and asthma, also to treat stomatitis, peptic ulcer and inflammatory diseases. (WHO.)

The major chemical constituents of the root are triterpene saponins. The root exhibits haemolytic action.... platycodon grandiflorum

Platypus

The platypus, Ornithorhynchus anatinus is found in fresh water streams along the eastern seaboard of Australia from Cooktown, in northern Queensland, to Tasmania. It is an unusual looking, furry mammal with a bill like a duck, webbed feet with claws (used for digging burrows), and a paddle -like tail for swimming. The male has spurs on its hind legs connected to venom glands. Venom injection causes excruciating, long-lasting pain needing hospital admission and treatment. Although never fatal in humans, death has occurred in hunting dogs.... platypus

Pleasance

(French) One who is agreeable Plaisance, Playsance, Plasance, Plesance... pleasance

Pleshette

(American) An extravagent woman

Pleshett, Pleshet, Pleshete, Plesheta, Pleshetta... pleshette

Plesmonium Margaritiferum

Schott.

Family: Araceae.

Habitat: Bengal, Chhota Nagpur, Ranchi, Purnea, Vishakhapatnam and Tamil Nadu.

Ayurvedic: Vajrakanda.

Folk: Kharhar (Uttar Pradesh).

Action: Anti-inflammatory (well- ground tubers are rubbed on swellings of the extremities). Seeds—externally applied to bruises. The tubers are poisonous (can be eaten after several boilings).... plesmonium margaritiferum

Plectranthus Mollis

Spreng.

Synonym: P. incanus Link.

Family: Labiatae; Lamiaceae.

Habitat: Temperate Himalayas from Simla to Sikkim and in Bihar, Madhya Pradesh and Western Ghats.

Folk: Laal-Aghaadaa (Maharashtra).

Action: Leaves—styptic, febrifuge.

The aerial parts yielded an essential oil (0.35%) containing piperitenone oxide (45.01) and cis-pipestone oxide (35.70%) as major constituents.

The antimicrobial activity of 10 mg of the oil was found to be the same as that of 10 units of penicillin G. sodium. The essential oil also exhibited cardiac depressant, respiratory stimulant and vasoconstrictor action. The leaves and flowering tops, in addition to the oil, also contain resin and tannin.... plectranthus mollis

Plethysmograph

An apparatus for estimating changes in the size of any part placed in the apparatus; in this way changes in the volume of blood in a part can be measured.... plethysmograph

Pleun

(American) One who is good with words Pleune... pleun

Pleurisy Root

Asclepias tuberosa. N.O. Asclepiadaceae.

Synonym: Butterfly Weed, Tuber Root, Wind Root.

Habitat: Moist, loamy soil. Indigenous to U.S.A

Features ? Stem two to three feet high, contains milky juice. Root, wrinkled longitudinally, light brown outer surface, whitish internally ; fracture tough, irregular. Rootstock knotty, faintly ringed. Acrid taste.

Part used ? Root.

Action: Diaphoretic, expectorant, antispasmodic.

Chest complaints; acts directly on the lungs, and stimulates sweat glands. Relaxes capillaries, relieving strain on heart and lungs. Reduces pain and assists breathing in pleurisy. Infusion of 1 ounce of the powdered root with 1 pint of boiling water is taken in wineglass doses, to which a teaspoonful of composition powder (Myrica compound) may be added with advantage.... pleurisy root

Pleurisy Root Tea - Tea Of The Indigenous Indians

Pleurisy root tea is an aromatic herbal tea which you are bound to enjoy. The indigenous Indians used to drink it a lot, especially thanks to its health benefits. About Pleurisy Root Tea Pleurisy root tea is made from the roots of the pleurisy plant, also known as the butterfly weed. The plant grows in North America. It can grow up to 1m tall, with multiple stems and spirally-arranged, spear-pointed leaves that are 5-12cm long. Clusters of orange or yellow flowers bloom during summertime, attracting butterflies, insects and birds. The plant can be found growing on dry, open fields, under direct sunlight. How to prepare Pleurisy Root Tea If you want to enjoy a cup of pleurisy root tea, add a teaspoon of dried, chopped roots to a cup of freshly boiled water. Let it steep for 10-15 minutes before straining it to remove the herbs. Sweeten it with honey or fruit juice, if necessary. Pleurisy Root Tea Benefits Pleurisy root contains various active constituents, such as glycosides, resins, amino acids, volatile oil, glucosidal principal, lupeol, and alkaloids. They are transferred to the pleurisy root tea, as well. Because if this, the tea has lots of important health benefits. Pleurisy root tea is often included in treatments for various respiratory ailments and pulmonary infections, for example pleurisy, asthma, bronchitis or pneumonia. It helps alleviate pain and congestion by reducing the mucus thickness in the lungs and enabling the patient to expel the blockage. Drinking pleurisy root tea helps both with fevers and detoxification, as it stimulates sweating and perspiration. It is also useful as an herbal treatment for colds and influenza. You can also drink pleurisy root tea if you’ve got problems with diarrhea, dysentery, chronic rheumatism, colic, muscle tension and spasm. Pleurisy root tea can also be used topically. You can soak a clean cloth with the tea and use it to treat swellings, bruises, lameness, wounds and skin ulcers. Pleurisy Root Tea Side Effects If you’re pregnant, you shouldn’t drink pleurisy root tea. It may cause uterine contractions, which could lead to miscarriages. Also, it is safer not to drink this tea if you’re breast feeding. Children shouldn’t drink pleurisy root tea either, because of the small amount of cardiac glycosides. You should be careful with the amount of pleurisy root tea you drink if you’ve got cardiovascular problems or you’re taking cardiac glycosides. Also, if you’re taking any other medication, check with your doctor if it’s safe to drink pleurisy root tea. Don’t drink more than 3-4 cups of pleurisy root tea a day. If you drink too much, it might lead to symptoms such as intestinal cramping, nausea, vomiting, and diarrhea. Pleurisy root tea is ideal for an everyday beverage. It has many health benefits and only a few side effects. Once you try it, you’ll surely enjoy it!... pleurisy root tea - tea of the indigenous indians

Plot Weed

Protection... plot weed

Pluchea Indica

Less.

Family: Compositae; Asteraceae.

Habitat: Sundarbans, in salt marshes and mangrove swamps.

Folk: Kukarondh, Manjurukh (Bengal).

Action: Root and leaves—astringent, antipyretic; given in decoction as a diaphoretic in fevers. Leaf— juice is given for dysentery; an infusion for lumbago, also against leucorrhoea. Root—antiinflammatory, hepatoprotective.

The aerial parts contain terpenic glycosides. The root contains sesqui- terpenes, lignin glycosides, thiophene derivatives.

The extracts of defatted roots showed significant anti-inflammatory activity. The extracts inhibited protein exudation and leucocyte migration.

Neuropharmacological studies on different experimental models of rodents exhibited potent central nervous system depressant activity.

The methanolic fraction of the extract exhibited significant hepatopro- tective activity against induced hepa- totoxicity in rats and mice. The extract also caused significant reduction in the elevated serum enzyme levels and serum bilirubin content in acute liver injury.... pluchea indica

Pluchea Lanceolata

C. B. Clarke.

Family: Compositae; Asteraceae.

Habitat: Punjab, Upper Gangetic plains, Gujarat, Rajasthan.

Ayurvedic: Raasnaa, Rasanaa, Raas- nikaa, Rasaa, Yuktaa, Yuktrasaa, Suvahaa, Elaaparni.

Folk: Vaaya-surai (Uttar Pradesh), Raayasan.

Action: Aerial parts—smooth muscle relaxant. Stem—antiinflammatory. Pluchea lanceolata is the source of Raasnaa in Punjab, Uttar Pradesh and Gujarat. Vanda roxburghii is used as Raasnaa in Bengal. Throughout South India, Alpinia galanga is accepted as Raasnaa.

The stem and leaves contain morete- nol, moretenol acetate, neolupenol, oc- tacosanoic, hexacosanoic and tetra- cosanoic acid, tetracosanol, hexaco- sanol, triacontanol, stigmasterol and beta-sitosterol-D-glucoside.

The petroleum extract of the stem and leaves and the chloroform-soluble portion of the methanolic extract exhibited 31.9% and 54.5% antioedema activity, respectively. The triterpenes, moretenol acetate, moretenol and ne- olupenol exhibited 55.2,32,8 and 39.7% anti-inflammatory activity respectively as against ibuprofen as standard exhibiting 65.5% activity.... pluchea lanceolata

Plumbago Capensis

Thunb.

Synonym: P. auriculata Lam.

Family: Plumbaginaceae.

Habitat: Native to South Africa; grown in gardens in India.

Ayurvedic: Nila-chitraka (blue- flowered var.). (Bears pale-blue flowers.)

Action: See P. zeylanica.... plumbago capensis

Plumbago Indica

Linn.

Synonym: P. rosea Linn.

Family: Plumbaginaceae.

Habitat: Indigenous to Sikkim and khasi hills, grown in Indian gardens.

English: Rose-coloured Leadwort.

Ayurvedic: Rakta-chitraka (red- flowered var.).

Siddha/Tamil: Chittramoolam.

Action: See P. zeylanica. P indica is preferred in West Bengal and Kerala. Both P. indica and P. zeylanica contain about 0.9 plumbagin.... plumbago indica

Plumeria

Love... plumeria

Pluralistic System

A system that is based on incorporating divergent provider modalities (e.g. public, private, non-profit, etc.).... pluralistic system

Plumbago Zeylanica

Linn.

Family: Plumbaginaceae.

Habitat: Cultivated in gardens throughout India; also found wild in Peninsular India.

English: Ceylon Leadwort, Leadwort.

Ayurvedic: Chitraka, Agni, Vahni, Jvalanaakhya, Krshaanu, Hutaasha, Dahana, Sikhi.

Unani: Sheetraj Hindi. Siddha/Tamil: Chittramoolam.

Action: Root—intestinal flora normalizer, stimulates digestive processes; used for dyspepsia. Root paste is applied in order to open abscesses; a paste prepared with milk, vinegar or salt and water, is used externally in leprosy and other obstinate skin diseases. A cold infusion is used for influenza and black-water fever.

Key application: In sprue, malabsorption syndrome, piles and inflammatory diseases of ano-rectum. (The Ayurvedic Pharmacopoeia of India.)

The root yielded naphthoquinone derivatives, plumbagin being the most important active principle.

The root extract, after processing for plumbagin enhancement, has been used in a number of drug formulations for liver ailments. Experimentally, plumbagin prevented the accumulation of triglycerides in liver and aorta and regressed atheromatous plaques and abdominal aorta. The chloroform extract of the root showed significant activity against pencillin-resistant (also non-pencillin resistant) strains of Neisseria gonorrhoea. (The root is used for treating sexually transmitted diseases in traditional Indian medicine.)

In Siddha medicine, in Tamil Nadu, the plant is an ingredient in a number of drug formulations for treating cancers of the uterus, breast, lungs and oral cavity, in addition to haemorrhoids.

Plumbagin is abortifacient, antiovu- latory; causes selective testicular lesions in dogs; in lower doses it behaves like a spindle poison, in higher concentration exhibits radiomimetic nu- cleotoxic and cytotoxic effects.

Dosage: Detoxified root—1-2 g powder. (API, Vol. I.)... plumbago zeylanica

Plumeria Acuminata

Ait.

Family: Apocynaceae.

Habitat: Native to Mexico; cultivated in Indian gardens.

English: Pagoda tree.

Action: Root bark—used in herpes, sexually transmitted diseases. Bark—stimulant, emmenagogue. Root—violent cathartic. Latex— purgative, rubefacient.

Iridoids are present in the leaf, stem, flower and root. Plumieride glucoside has been isolated from all parts of the plant. The plumeric acid, isolated from leaves, exhibits promising cytotoxic activity.

Fulvoplumierin (a pigment) inhibits the growth of various strains of My- cobacterium tuberculosis.... plumeria acuminata

Plumeria Alba

Linn.

Family: Apocynaceae.

Habitat: Native to West Indies; cultivated in Indian gardens.

English: White Champa.

Ayurvedic: Kshira Champaka (white-flowered var.).

Siddha/Tamil: Perumal Arali, Seemai Arali.

Action: Root bark—used in blenn- orrhagia. Bark and latex—used externally in herpes, syphilitic ulcers and scabies. Seed—haemostatic.

The root gave iridoids—iso-plu- mericin, plumericin, plumieride, plu- mieride coumarate and its glucoside. The bark gave alpha-and beta-amyrin and their acetates, beta-sitosterol, sco- poletin and plumieride. The flowers also contain plumieride coumarate and its glucoside, in addition to quercetin derivatives.... plumeria alba

Plumeria Rubra

Linn.

Family: Apocynaceae.

Habitat: Native to Mexico; grown throughout India.

English: Red Jasmine.

Ayurvedic: Kshira Champaka (red-flowered var.).

Action: Root bark—used in blennorrhagia. Flower—bechic (used in pectoral syrups). Bark— a decoction is used in venereal diseases and leprosy.

The bark contains cytotoxic iridoids (including fulvoplumierin which also inhibits the growth of Mycobacterium tuberculosis) and the lignin, lirioden- drin.

The plant contains the triterpene rubrinol which showed antibacterial activity against Gram-positive and Gram-negative bacteria, including Pseudomonas aeruginosa (a causative agent responsible for infecting burns, wounds, urinary tract and infection in cystic fibrosis) and Pseudomonas pseu- domallei (which causes melioidosis or pseudoglandess).

The herb contains cardiac glycosides which have a narrow-margin of safety. (Sharon M. Herr.)... plumeria rubra

Pneumocystis Carinii

A fungus, formally believed to be a protozoan, which may cause an atypical pneumonia in severely malnourished or immunologically compromised patients, e.g. AIDS patients.... pneumocystis carinii

Pneumonopathy

Any disease of the lungs... pneumonopathy

Pneumonosis

Any lung disorder... pneumonosis

Pneumorrhagia

A severe haemoptysis... pneumorrhagia

Pocahontas

(Native American) Filled with j°y

Pokahontas, Pocohontas, Pokohontas, Pocahantas, Pokahantas... pocahontas

Podarge

(Greek) In mythology, one of the Harpies... podarge

Podophyllum Hexandrum

Royle.

Synonym: P. emodi Wall. ex Hook. f. & Thoms.

Family: Berberidaceae.

Habitat: Inner ranges of the Himalayas, from Kashmir to Sikkim at 1,800-4,000 m.

English: Indian Podophyllum.

Ayurvedic: Giriparpata.

Folk: Bana-kakari (Punjab), Venivel (Gujarat), Patvel (Maharashtra). Paapraa, Paapri.

Action: Rhizomes and roots— antineoplastic. Strongly irritant to skin and mucous membranes. Used topically as an ointment for venereal warts, verrucae and similar conditions.

Key application: P. peltatum— externally, for removal of pointed condyloma (skin adjacent to the treated area should be protected). (German Commission E.) P hexandrum: Podophyllin (10-40%) for external application, 2-6 h weekly, for anogenital warts. (Indian Herbal Pharmacopoeia.) (Podophyllin is a mitotic poison.)

May Apple of North America is equated with Podophyllum peltatum Linn. The main lignin is podophyllo- toxin. Podophyllum hexandrum contains similar lignans with the exception of alpha-and beta-peltatins, which are reportedly absent; the concentration of podophyllotoxin is up to 4.3%. P. peltatum contains about 0.25% and the Taiwanese species P. pleianthum 0.1% podophyllotoxin.

(Podophyllotoxin is a valuable lig- nin, as it is used for the synthesis of chemically administered cytostat- ic etoposide and tenoposide.)... podophyllum hexandrum

Podophyllum Sikkimensis

R. Chatterji & Mukerjee.

Family: Berberidaceae.

Habitat: Sikkim.

Folk: Paapraa (var.).

Action: Resin—used against tumours.

The rhizomes and roots yield 7.5% resin which gave a lignin lactone desig nated sikkimotoxin; also 3-galactosidyl quercetin, quercetin and isorhamne- tin. It is yet to be established that the lactone possesses properties analogous to those of podophyllotoxin.... podophyllum sikkimensis

Poetry

(American) A romantic woman Poetrey, Poetri, Poetrie, Poetree, Poetrea... poetry

Pogostemon Parviflorus

Benth.

Synonym: P. pubescens Benth.

Family: Labiatae; Lamiaceae.

Habitat: Hills of South-western India, ascending to 1,200 m.

Folk: Phaangalaa (Maharashtra).

Action: Aerial parts—antifungal, antibacterial.

Acetone extract of the aerial parts exhibits larvicidal activity against the larva of malaria vector, Anopheles ste- phensi and Culex quinquefasciatus.... pogostemon parviflorus

Poke

Courage, Hex Breaking... poke

Polete

(Hawaiian) A kind young woman Polet, Polett, Polette, Poleta, Poletta... polete

Pogostemon Benghalensis

Kuntze.

Synonym: P. plectranthoides Desf.

Family: Labiatae; Lamiaceae.

Habitat: Throughout greater part of India.

Folk: Ishwar-jataa. Jui-lataa (Bihar, Bengal). Phaangalaa (Maharashtra).

Action: Root—used in haemorrhage, especially in uterine haemorrhage. Leaf—styptic; used for cleaning wounds. Essential oil—antifungal. Acetone extract— insecticidal, insect repellent.

Pogostemonpubescens Benth., synonym P. parviflorus Benth. is also known as Phaangalaa in Maharashtra. Aerial part exhibits antifungal and leaf antibacterial activity.

Sesquiterpene lactone, caryophyl- len-9-beta-10-olide, has been isolated from the whole plant.

Pogostemon purpurascens Dalz. (Manipur and South-western India) also possesses properties similar to P. benghalensis. The acetone extract exhibited larvicidal activity against the larvae of malaria vector, Anopheles stephensi. It also showed activity against yellow fever mosquito.... pogostemon benghalensis

Pogostemon Cablin

Benth.

Synonym: P. patchouli var. sauvis Hook. f.

Family: Labiatae; Lamiaceae.

Habitat: Native to the Philippines; introduced in India.

English: Patchouli.

Ayurvedic: Paachi.

Folk: Paanari.

Action: Plant—insecticidal. Leaves—an infusion is given in menstrual troubles.

The oil, extracted from dried leaves, is reported to possess antibacterial activity against E. coli, Staphylococcus au- reus, Streptococcus pyogenes, Bacterium coli and B. typhosum. It is also found effective against Mycobacterium tuberculosis. The oil is used in insect- repellent preparations.... pogostemon cablin

Pogostemon Patchoulis

Hook. f. non-Pelletier.

Synonym: P. heyneanus Benth.

Family: Labiatae; Lamiaceae.

Habitat: Western Ghats of Karnataka, Kerala and the Nilgiri hills up to 1,800 m.

English: Patchouli.

Ayurvedic: Paachi, Pancholi.

Siddha/Tamil: Kadir Pachai.

Folk: Paanch (Maharashtra), Sugandhi Paanadi (Gujarat).

Action: Leaf—bechic, antiasthmatic. A poultice of leaves is applied to boils and to relieve headache.

The plant gave alpha-pyrone derivatives, pogopyrones A and B; n-octaco- sanol, beta-sitosterol and its glucoside and several flavones. Pogopyrone B exhibited cytotoxic activity.... pogostemon patchoulis

Poke Root

Phytolacca decandra. N.O. Phytolaccaceae.

Synonym: Garget, Pigeon Berry.

Habitat: U.S.A. Cultivated on a sm.ill scale in England for medicinal purposes.

Features ? The root is obtainable in longitudinally split pieces or in transverse slices. Ringed, brownish-grey externally, hard and whitish inside; fibrous fracture. Berries purplish-black, nearly globular, ten carpels, each containing one lens-shaped seed.

Part used ? Root, berries.

Action: Alterative, cathartic.

Chronic rheumatism and skin diseases. Of some use in dyspepsia. Action of root stronger than berries. For rheumatism the root is often compounded with Black Cohosh and Wintergreen.

Preparation and dosage vary considerably with the condition of the root. Thurston, Hammer and other physio-medical practitioners recommend that only the green root should be used, owing to, rapid deterioration. These herbalists use the fresh root largely in hardening of the liver and reduced biliary flow.... poke root

Policy Formulation

The development of a policy.... policy formulation

Polina

(Russian) A small woman Polinah, Poleena, Poleenah, Poleana, Poleanah, Poliena, Polienah, Poleina, Poleinah, Polyna, Polynah... polina

Polly

(English) Form of Mary, meaning “star of the sea / from the sea of bitterness” Polley, Polli, Pollie, Pall, Paili, Paley, Paliki, Poll, Pollyanna, Pollyana, Pollee, Pollea... polly

Polvo De

“Powder of (plant or mineral name)”; see plant or mineral name specified.... polvo de

Poisons

A poison is any substance which, if absorbed by, introduced into or applied to a living organism, may cause illness or death. The term ‘toxin’ is often used to refer to a poison of biological origin. Toxins are therefore a subgroup of poisons, but often little distinction is made between the terms. The study of the effects of poisons is toxicology and the effects of toxins, toxinology.

The concept of the dose-response is important for understanding the risk of exposure to a particular substance. This is embodied in a statement by Paracelsus (c.1493–1541): ‘All substances are poisons; there is none which is not a poison. The right dose di?erentiates a poison and a remedy.’

Poisoning may occur in a variety of ways: deliberate – SUICIDE, substance abuse or murder; accidental – including accidental overdose of medicines; occupational; and environmental

– including exposure during ?re.

Ingestion is the most common route of exposure, but poisoning may also occur through inhalation, absorption through the skin, by injection and through bites and stings of venomous animals. Poisoning may be described as acute, where a single exposure produces clinical effects with a relatively rapid onset; or chronic, where prolonged or repeated exposures may produce clinical effects which may be insidious in onset, cumulative and in some cases permanent.

Diagnosis of poisoning is usually by circumstantial evidence or elimination of other causes of the clinical condition of the patient. Some substances (e.g. opioids) produce a characteristic clinical picture in overdose that can help with diagnosis. In some patients laboratory analysis of body ?uids or the substance taken may be useful to determine or con?rm the o?ending agent. Routine assays are not necessary. For a very small number of poisons, such as paracetamol, aspirin, iron and lead, the management of the patient may depend on measuring the amount of poison in the bloodstream.

Accurate statistics on the incidence of poisoning in the UK are lacking. Mortality ?gures are more reliable than morbidity statistics; annually, well over 100,000 cases of poisoning are admitted to hospital. The annual number of deaths from poisoning is relatively small – about 300 – and in most cases patients die before reaching hospital. Currently, CARBON MONOXIDE (CO) is by far the most common cause of death due to poisoning. The most common agents involved in intentional or accidental poisoning are drugs, particularly ANALGESICS, ANTIDEPRESSANT DRUGS and SEDATIVES. Alcohol is also commonly taken by adults, usually in combination with drugs. Children frequently swallow household cleaners, white spirit, plant material – such as belladonna (deadly nightshade) and certain mushrooms; for example, death cap and ?y agaric – aftershave and perfume as well as drugs. If possible, the suspect container, drug or plant should be taken with the victim to the hospital or doctor. The use of child-resistant containers has reduced the number of admissions of children to hospital for treatment. Bixtrex® is an intensely bitter-tasting agent which is often added to products to discourage ingestion; however, not everybody is able to taste it, nor has any bene?cial e?ect been proven.

Treatment of poisoning usually begins with decontamination procedures. For ingested substances this may involve making the patient sick or washing the stomach out (GASTRIC LAVAGE): this is usually only worthwhile if performed soon after ingestion. It should be emphasised that salt (sodium chloride) water must never be given to induce vomiting, since this procedure is dangerous and has caused death. For substances spilt on the skin, the affected area should immediately be thoroughly washed and all contaminated clothing removed. Following eye exposure, the affected eye/s should be thoroughly irrigated with saline or water.

Treatment thereafter is generally symptomatic and supportive, with maintenance of the victim’s respiratory, neurological and cardiovascular systems and, where appropriate, monitoring of their ?uid and electrolyte balance and hepatic and renal function. There are speci?c antidotes for a few substances: the most important of these are PARACETAMOL, iron, cyanide (see CYANIDE POISONING), opioids (see OPIOID), DIGOXIN, insecticides and some heavy metals. Heavy-metal poisoning is treated with CHELATING AGENTS – chemical compounds that form complexes by binding metal ions: desferrioxamine and pencillinamine are two such agents. The number of people presenting with paracetamol overdose – a common drug used for attempted suicide – has fallen sharply since restrictions were placed on its over-thecounter sales.

When a patient presents with an illness thought to be caused by exposure to substances at work, further exposure should be limited or prevented and investigations undertaken to determine the source and extent of the problem. Acutely poisoned workers will usually go to hospital, but those suffering from chronic exposure may attend their GP with non-speci?c symptoms (see OCCUPATIONAL HEALTH, MEDICINE AND DISEASES).

In recent years, legislation has been enacted in the UK to improve safety in the workplace and to ensure that data on the hazardous constituents and effects of chemicals are more readily available. These o?cial controls include the Control of Substances Hazardous to Health (COSHH) and the Chemicals (Hazard Information and Packaging) Regulations (CHIP) and are UK legislation in response to European Union directives.

The National Poisons Information Service is a 24-hour emergency telephone service available to the medical profession and provides information on the likely effects of numerous agents and advice on the management of the poisoned patient. The telephone numbers are available in the medical literature. In the UK this is not a public-access service. People who believe they, or their relatives, have been poisoned should seek medical advice from their GPs or attend their local hospital.

Toxbase The National Poisons Information Service provides a primary clinical toxicology database on the Internet: www.spib.axl.co.uk. This website provides information about routine diagnosis, treatment and management of people exposed to drugs, household products and industrial and agricultural products.

(See also APPENDIX 1: BASIC FIRST AID.)... poisons

Polychromatophilia

See POLYCHROMASIA.... polychromatophilia

Polycystic Disease Of The Kidney

An inherited disease in which the KIDNEYS contain many cysts. These grow in size until normal kidney tissue is largely destroyed. Cysts may also occur in other organs such as the liver. In adults, the disease will cause HYPERTENSION and kidney failure. There is also a juvenile form. There is no e?ective treatment, although symptoms can be alleviated by DIALYSIS and sometimes kidney transplant (see TRANSPLANTATION).... polycystic disease of the kidney

Pokeweed

Phytolacca americana

Description: This plant may grow as high as 3 meters. Its leaves are elliptic and up to 1 meter in length. It produces many large clusters of purple fruits in late spring.

Habitat and Distribution: Look for this plant in open, sunny areas in forest clearings, in fields, and along roadsides in eastern North America, Central America, and the Caribbean.

Edible Parts: The young leaves and stems are edible cooked. Boil them twice, discarding the water from the first boiling. The fruits are edible if cooked.

CAUTION

All parts of this plant are poisonous if eaten raw. Never eat the underground portions of the plant as these contain the highest concentrations of the poisons. Do not eat any plant over 25 centimeters tall or when red is showing in the plant.

Other Uses: Use the juice of fresh berries as a dye.... pokeweed

Polianthes Tuberosa

Linn.

Family: Amaryllidaceae.

Habitat: Native to Mexico; cultivated for ornamental use.

English: Tuberose.

Ayurvedic: Rajanigandhaa.

Siddha/Tamil: Nilasampangi.

Folk: Gulcheri, Gulshabbu.

Action: Flowers and bulbs— diuretic. Externally used for skin eruptions. The bulbs are rubbed with turmeric and butter and applied over red pimples of infants. The bulbs are reported to contain an alkaloid, lycorin, which causes vomiting.

Dried and powdered bulbs are used for gonorrhoea.... polianthes tuberosa

Polyalthia Longifolia

Thw.

Family: Annonaceae.

Habitat: Native to Sri Lanka; grown in gardens throughout the warmer parts of India.

English: Mast tree, Fake Asoka tree, False Devadaru, Cemetry tree

Ayurvedic: Devadaari (Devadaaru is equated with Cedrus deodara). (An adulterant to the bark of Saraca asoca.)

Siddha/Tamil: Nettilingam.

Action: Febrifuge. Causes cardiac depression.

The stem bark contains clerodane diterpenes, polyalthialdoic acid and kolavenic acid. The stem and its bark also contain the cytotoxic aporphine alkaloid, liriodenine, besides nor-oli- veroline and oliveroline-beta-N-oxide. Azafluorene alkaloids are also present in the bark and leaves. The leaf exhibits fungitoxic activity.

Polyalthia simiarum Hook. f. & Thoms. (Orissa, Assam, Bengal, Bihar, Eastern Himalaya) is also equated with Fake Ashoka tree. It is known as Boga-khamtou in Assam, Wojarah, Mongai in Orissa and Labshi, Kutti in Nepal.

Polyalthia suberosa Thw. (from Assam to Uttar Pradesh in the North and Kerala in the South) is known as Chamkhirni. The leaves contain alpha-and beta-amyrin, lupeol, beta- sitosterol, stigmasterol and campes- terol. The stems and leaves contain the triterpene, suberosol, which showed anti-HIV replication activity. The stem bark contains alkaloids, oxostepha- nine and lanuginosine, which exhibited antibacterial activity against several Gram-positive and Gram-negative bacteria.... polyalthia longifolia

Polycarpaea Corymbosa

Lam.

Family: Caryophyllaceae.

Habitat: Throughout the greater part of India, ascending up to 2,100 m in the Himalaya.

Ayurvedic: Parpata (substitute).

Siddha/Tamil: Nilaisedachi.

Folk: Pittapaaparaa (Uttar Pradesh), Rupaaphuli (Gujarat).

Action: Leaves—anti-inflammatory, applied as poultice. Also prescribed in jaundice in the form of pills with molasses. Flowering head, along with stem and leaves—astringent, demulcent. Plant—spermicidal.

The plant gave camelliagenins (bar- rigenol) and stigmasterol.... polycarpaea corymbosa

Polycarpon Prostratum

(Forsk.) Alschers & Schweinf.

Synonym: P. loeflingii Benth. & Hook. f.

Habitat: Throughout the warmer parts of India in fields and waste places.

Folk: Ghima, Suretaa.

Action: Leaves—an infusion of roasted leaves is given for cough following fever, particularly in measles.

Alcoholic extract of the plant exhibits spasmolytic activity. The aerial parts contain tetrahydroxy triterpenes. Presence ofa triterpenoid saponin, and hentriacontane, hentriacontanol, beta- amyrin and its acetate, beta-sitosterol and stigmasterol is also reported.... polycarpon prostratum

Polyenes

Antifungal agents that include AMPHOTERICIN (given by intravenous injection in the treatment of systemic ASPERGILLOSIS) and NYSTATIN, applied topically for fungus infection of the skin, mouth and other mucous membranes.... polyenes

Polygala Crotalarioides

Buch.-Ham. ex DC.

Family: Polygalaceae.

Habitat: Tropical Himalayas from Simla to Sikkim and the Khasi Hills.

Folk: Lilakanthi, Lilakaathi. (Bihar). Maraad (var.).

Action: Root—used for cough and pulmonary catarrh; chewed or ground and drunk with water to expel phlegm from the throat; provokes coughing.... polygala crotalarioides

Polygala Chinensis

Auct. Non Linn.

Synonym: P. arvensis Willd.

Family: Polygalaceae.

Habitat: Throughout India and the Andamans.

English: Senega.

Folk: Meradu, Maraad, Negali (Maharashtra). Maraad (Nepal).

Action: Root—antiasthmatic; used as a substitute for Senega obtained from the American plant Polygala senega. (In Chinese medicine Senega refers to P. tenuifolia Willd.)

Key application: Senega Root— in productive cough, catarrh of the respiratory tract and chronic bronchitis. (German Commission E, ESCOP, WHO.)

Senega yielded lactonic lignans, their glycosides and flavonol glycosides. The root gave arctiin, afzelin, myricitrin and rutin. A triterpenic saponin was also obtained from the plant. The root contains salicylic acid, methyl salicylate and senegin (a sapo- nin mixture).

Senega is used for chronic bronchitis, catarrh, asthma and croup, as an infusion.

Related species are: P. chinesis Linn., synonym P. glomerata Lour; P. tele- phioides Willd., synonym P. brachys- tachya DC. non-Bl., found throughout the plains of India. Both the plants are used as expectorant, antiasthmatic and anticatarrhal.

Toxic constituents of Polygala senega root are: triterpene saponins—6- 16% senegasaponins A-D with agly- cone presenegenin or senegin. Sapo- nins irritate GI tract mucosa and cause reflex secretion of mucous in the bronchioles.

A French patent is used against graft rejection, eczema and multiple sclerosis as an anti-inflammatory drug.... polygala chinensis

Polygala Sibirica

Linn.

Synonym: P. heyneana Wall. ex W. & A.

Family: Polygalaceae.

Habitat: Throughout the Himalayas and Western Ghats.

English: Common Milkwort.

Folk: Negali, Meradu (var.).

Action: Leaves—used in spermatorrhoea. Root—a decoction is given as an expectorant in cold and cough and chronic chest diseases. (Used as a substitute for Senega.) Also used for inflammation of urinary bladder; externally for mammary abscesses and carbuncles.... polygala sibirica

Polygonum Affine

D. Don.

Synonym: Bistorta affinis (D. Don) Green.

Family: Polygonaceae.

Habitat: Himalayas from Kashmir to Nepal at altitudes of 2,4004,800 m.

Folk: Khukhudi.

Action: Flowers—stimulant.

The inflorescence gave flavonoids, including quercetin, isorhamnetin, lu- teolin and apigenin derivatives. The leaves contain the flavonoids, 8-C- glucosyltricin and isorhamnetin.... polygonum affine

Polygonum Plebeium

R.Br.

Family: Polygonaceae.

English: Throughout warmer parts of India in moist areas, ascending to 2,100 m in the Himalayas.

Ayurvedic: Sarpaakshi (a confusing synonym).... polygonum plebeium

Polyhymnia

(Greek) In mythology, the muse of sacred songs and dance Polyhymniah, Polymnia, Polymniah... polyhymnia

Polygonatum Cirrhifolium

(Wall.) Royle.

Family: Liliaceae.

Habitat: Northern Himalayas, from 1,500 to 3,300 m.

Ayurvedic: Mahaa-medaa, Medaa, (substitute: Asparagus racemosus, also Saalab-misri.)

Folk: Devarigaanl (Gharwal).

Action: Root—rejuvenating tonic for nervous system.

The root gave neoprazerigenin A- 3-O-beta-lycotetraoside (PS-III) and its methyl proto-type congener (PS- II) and steroidal saponins, sibiricoside A (PS-I) and sibiricoside B (PS-IV).

Dosage: Root—3-5 g powder. (CCRAS.)... polygonatum cirrhifolium

Polygonatum Multiflorum

All.

Family: Liliaceae.

Habitat: Western Himalayas from Kashmir to Kumaon and in Manipur.

English: Solomon's Seal.

Ayurvedic: Mahaa-medaa, Medaa (var.). (Substitute: Asparagus racemosus.)

Action: Anti-inflammatory, nervine, astringent. Used as an infusion for pulmonary complaints; as a poultice for piles and bruises.

The root and herb gave diosgenin and its glycosides.

Dosage: Root—3-5 g powder. (CCRAS.)... polygonatum multiflorum

Polygonatum Verticillatum

All.

Family: Liliaceae.

Habitat: Temperate Himalayas and Manipur.

Ayurvedic: Medaa. (Substitute: Asparagus racemosus.)

Unani: Shaqaaqul. (Substitute: Pastinaca secacul.)

Folk: Mithaa-dudhiaa.

Action: Used in Tibetan medicine for treating emaciation, senility, pulmonary affections. The rhizomes is valued as salep.

The dried rhizomes contain 6.2-9% diosgenin.

The lactins of the rootstock did not contain carbohydrates; the amino acid revealed presence of 28% aspartic acid and asparagine.

The plant exhibits diuretic properties. It gave a digitalis glucoside and is considered poisonous by the hill people in the Himalayas.... polygonatum verticillatum

Polygonum Aviculare

Linn.

Family: Polygonaceae.

Habitat: From Kashmir to Kumaon.

English: Knotgrass, Knotweed, Mexican Sanguinaria.

Folk: Machoti, Kesri.

Action: Astringent and haemostatic. Used for excessive menstruation, bleeding piles; bleeding from bowel, stomach, lungs, nose, throat; mucous colitis, children's summer diarrhoea.

Key application: In mild catarrhs of the respiratory tract, inflammatory changes to the oral and pharyngeal mucosa. (German Commission E.)

The plant gave flavonoids including quercetin, avicularin, quercitrin, and derivatives of kaempferol, esculetin and scopoletin. The plant also gave gallic, caffeic, oxalic., silicic, chloro- genic and p-coumaric acids; tannins including catechin.

The methanolic extract of the plant showed high protection against CCl4- induced hepatotoxicity in mice. This activity is attributed to the presence of flavonoid glucosides.

The flavonoids exhibit astringent properties and are found to decrease capillary fragility and have a cortisonelike-effect on gingival tissue. (J Ethno- pharmacol, 74(1), 2001.)... polygonum aviculare

Polygonum Bistorta

Linn.

Synonym: P. paleaceum Wall. ex Hook. f.

Family: Polygonaceae.

Habitat: The Himalayas from Kashmir to Sikkim and the hills of Assam.

English: Snake Weed, Bistort, Dragon Wort.

Unani: Anjabaar.

Action: Anti-inflammatory, haemostatic, astringent, demulcent, anticatarrhal, antidiarrhoeal. Used for internal haemorrhages, irritable bowel, diverticulosis, urinary and uterine affections. Used as a mouth wash and gargle for ulcerated mouth and bleeding gums.

The herb contains ferulic, sinapic, vanillic, syringic, melilotic, p-couma- ric, p-hydroxybenzoic, gentisic, sali- cyclic and ellagic acids, about 15-20% tannins mainly catechins.

When administered before the induction of adjuvant arthritis, the aqueous-ethanolic extract of the herb inhibited both the maximal oedema response and the total oedema response in rat.... polygonum bistorta

Polymyxin

A group of antibiotics derived from various species of Bacillus polymyxa. One variety, colistin, is used to sterilise the bowels before surgery as it is not absorbed when given by mouth. The drugs are sometimes used in topical applications for infections of the skin, eye and ear.... polymyxin

Polygonum Glabrum

Willd.

Family: Polygonaceae.

Habitat: Throughout India in marshy places, up to 1,900 m. in the hills.

Ayurvedic: Rakta-rohidaa (Gujarat).

Siddha/Tamil: Attalaree.

Action: Plant juice and rootstock— used in pneumonia, consumption, jaundice, fevers. Leaf— antispasmodic. Used for colic.

The leaves contain flavonoids— quercetin, rhamnetin, quercitrin, avic- ularin and rutin. Flowers contain pigments, delphinidin-3,5-diglucoside and cyanidin-3,5-diglucoside and quercetin.

The methanolic aqueous extract of the leaf gave a pure anthelmintic substance, a terpenoid (PGA). (The herb is used as an anthelmintic in Sudan.)... polygonum glabrum

Polygonum Hydropiper

Linn.

Family: Polygonaceae.

Habitat: Throughout India in wet places.

English: Water Pepper, Pepperwort, Smartweed.

Folk: Paakur-muula, Paani-maricha (Bengal).

Action: Haemostatic, astringent, anti-inflammatory, diuretic, lithotriptic, emmenagogue (used as infusion for delayed menses and amenorrhoea), antifungal (root and leaf used externally). Contraindicated during pregnancy.

The herb contains sesquiterpenes, including warburganal and polygodial, in the leaves; polygonal, isodrimeni- nol, isopolygodial and confertifolin in the seeds; and flavonoids including quercetin, kaempferol, isorhamnetin and rhamnesin; polygonolide (an iso- coumarin).

Isoquercitrin exhibited significant anti-oxidative activity. Polygodial and warburganal possess significant an- tifungal property. Warburganal also possesses potent cytotoxic and antibiotic activity. (The herb is used against cancer.)

Folk: Muniyaaraa (Bihar), Raani- phool, Macheti, Dubiaa Saaga.

Action: Galactogenic, antidiar- rhoeal. Powdered herb is given in pneumonia.

The whole plant yields 11% tannin. The rootstock contains oxymethylan- thraquinone.

Flowers gave oleanolic acid, betulin- ic acid, epi-friedelanol, beta-sitosterol, and flavonoids—quercetin, quercetin- 3-arabinoside and quercetin-3-rutino- side.... polygonum hydropiper

Polygonum Viviparum

Linn.

Family: Polygonaceae.

Habitat: The Himalayas from Kashmir to Sikkim at 3,3004,800 m.

English: Viviparous Bistort.

Unani: Anjabaar. (substitute).

Folk: Billori, Maamekh (Punjab).

Action: Rootstock—astringent, antidiarrhoeal, antileucorrhoeic, antiseptic, antiperiodic. Used in haemoptysis; also for gleet. A decoction is used as a gargle for sore throat and spungy gums, as a lotion for ulcers.... polygonum viviparum

Polypill

A suggestion by two epidemiologists, made in the British Medical Journal in 2003, that many lives could be saved if all persons aged over 55 took a daily combination pill they termed the polypill. Its components would be ASPIRIN, a CHOLESTEROL-lowering agent, FOLIC ACID and two blood-pressure-lowering agents. The suggestion caused a massive correspondence as it implied treating a whole population rather than individuals considered to be at special risk.... polypill

Polypodium Vulgare

Linn.

Family: Polypodiaceae. English: Polypody Root. Unani: Bisfaayaj.

Action: Expectorant, laxative, stomachic, cholagogue, alterative, antistress. Used in cough, bronchitis, catarrh, loss of appetite, dyspepsia; and in skin diseases.

The rhizome gave saponin glyco- sides, based on polypodosapogenin, including osladin; ecdysteroids; phlo- roglucin derivatives; tannin.... polypodium vulgare

Polyxena

(Greek) In mythology, a daughter of Priam who was loved by Achilles Polyxenah, Polyxenia, Polyxenna, Polyxene, Polyxenea... polyxena

Pomada

Pomade, salve or ointment; an oil-based preparation of medicinal plants for external application, often used for healing skin ailments, muscle pain or sinus conditions.... pomada

Pomada De Manteca

Butter pomade; a slightly solidified nut butter used externally as an ointment or salve; for example, made from peanuts (maní) or sesame seeds (ajonjolí).... pomada de manteca

Polyporus Officinalis

Fries

Family: Polyporaceae.

Habitat: On the old trunks of various coniferous trees.

English: White Agaric.

Unani: Ghaariqoon.

Action: Used in the treatment of sweats in wasting diseases such as phthisis (it checks profuse sweats); also as an expectorant and diuretic.

The drug contains agaric acid (agari- cin). The resinous extract, when burnt, yields not more than 2% of a white ash, rich in phosphates. The drug gives 46% soft resin.

Agaric acid acts as a counter-irritant when applied to abraded surfaces or mucous membrane.... polyporus officinalis

Polyscias Fruticosa

(L.) Harms.

Synonym: Nothopanaxfruticosum (L.) Miq.

Panax fruticosus L.

Family: Araliaceae.

Habitat: Cultivated in gardens all over India.

Action: Leaf—used in sinusitis, headache, migraine, tonsillitis. Stem bark—used for promoting expulsion of placenta after child birth. Root— antibacterial, antifungal, diuretic. Leaf and root—used in dysuria.

The root contains polyacetylenes, falcarinol and heptadeca derivatives. Falcarinol and heptadeca exhibited strong antibacterial activity against Gram-positive bacteria and the der- matophytic bacteria, also showed an- tifungal activity. The antibacterial activity of falcarinol was found to be 15 to 35 times stronger than that of erythromycin, chloramphenicol and oxytetracyclin.

Polyscias scutellaria (Burm. f.) F. R. Fosberg (commonly grown in Indian gardens) exhibits anti-inflammatory activity. The leaves contain several tri- terpenoid saponins, polyscisaponins, oleanolic acid derivatives.... polyscias fruticosa

Pomona

(Latin) In mythology, goddess of fruit trees

Pomonah, Pomonia, Pomonea, Pamona, Pamonia, Pamonea... pomona

Pompa

(American) An arrogant woman Pompah, Pompy, Pompey, Pompee, Pompea, Pompi, Pompie... pompa

Pompeya

(Latin) Feminine form of Pompey; fifth-born child; woman from Pompeii

Pompaya, Pompaiya, Pompaeya... pompeya

Pongamia Pinnata

Pierre.

Synonym: P. glabra Vent. Derris indica (Lam.) Benett.

Family: Papilionaceae; Fabaceae.

Habitat: Western Ghats, tidal forests up to 1,200 m.

English: Pongam Oil tree, Indian Beech.

Ayurvedic: Karanja.

Siddha/Tamil: Pungam.

Action: Oil—applied in scabies, herpes, leucoderma and other cutaneous diseases; over chest in pneumonia and cold; also used internally as cholagogue in sluggish liver. Leaves—juice is prescribed in flatulence, dyspepsia, diarrhoea and cough. An infusion is given for leprosy and gonorrhoea. Root— a paste is used in scrofulous enlargements; juice is used for cleaning foul ulcers and closing fistulous sores. Stem bark—given internally in bleeding piles. Rind of pod and seed—prescribed in bronchitis and whooping cough. Leaf and seed—antileprotic. Leaf and seed oil—antirheumatic.

The tree is rich in flavonoids and related compounds. These include simple flavones, furanoflavonoids, chro- menoflavones, chromenochalcones, coumarones, flavone glucosides, sterols, triterpenes and a modified phenyl- alanine dipeptide. Seeds and seed oil gave karanjin, pongamol, pongapin and kanjone.

The aqueous extract of stem bark shows significant sedative and antipyretic effects in rats, and antispas- modic effect in vitro on smooth muscles.

In Indonesia, a decoction ofthe bark is drunk after child birth.

The aqueous extract of seeds showed significant antiviral activity against herpes simplex viruses HSV-1 and 2 cell lines experimentally. Albino rats, treated with the aqueous extract of seeds, recovered faster from induced infection and skin-burn than the untreated ones.

Dosage: Seed—250 mg powder; 510 g for decoction. (API, Vol. I.)... pongamia pinnata

Poni

(African) The second-born daughter Ponni, Ponie, Ponnie, Pony, Ponny, Poney, Ponney, Ponee, Ponnee, Ponea, Ponnea... poni

Poodle

(American) Resembling the dog; one with curly hair Poudle, Poodel, Poudel... poodle

Pooky

(American) A cute and cuddly girl Pookey, Pooki, Pookie, Pookee, Pookea... pooky

Poonam

(Hindi) A kind and caring woman Pounam... poonam

Poplar

Money, Flying... poplar

Popliteal Space

The name given to the region behind the knee. The muscles attached to the bones immediately above and below the knee bound a diamond-shaped space through which pass the main artery and vein of the limb (known in this part of their course as the popliteal artery and vein); the tibial and common peroneal nerves (which continue the sciatic nerve from the thigh down to the leg); the external saphenous vein; and several small nerves and lymphatic vessels. The muscles – which bound the upper angle of the space and which are attached to the leg bones by strong prominent tendons – are known as the hamstrings. The lower angle of the space lies between the two heads of the gastrocnemius muscle, which makes up the main bulk of the calf of the leg.... popliteal space

Population

A group of individuals or items that share one or more characteristics from which data can be gathered and analysed.... population

Population Ageing

The increase over time in the proportion of the population of a specified older age.... population ageing

Population Dynamics

The study of changes in the number and composition of individuals in a population and the factors that influence those changes. Population dynamics involves five basic components of interest, to which all changes in populations can be related: birth, death, sex ratio, age structure and dispersal.... population dynamics

Population Pyramid

A graphic presentation of the age and sex composition of the population.... population pyramid

Population-based Services

Health services targeted at populations with specific diseases or disorders.... population-based services

Pora

(Hebrew) A fertile woman Porah, Porrah, Porra, Poria, Poriah, Porea, Poreah... pora

Porphyrins

Complex organic compounds which are sensitive to light and form the basis of respiratory pigments – for example, haemoglobin and myoglobin. Porphyrins are crucial to many metabolic oxidation/reduction reactions in animals, plants, and micro-organisms.... porphyrins

Populus Alba

Linn.

Family: Salicaceae.

Habitat: Northwestern Himalaya at 1,200-3,000 m, also grown in avenues.

English: White Poplar.

Folk: Safedaa, Jangali Fraas.

Action: Bark—antirheumatic, anti-inflammatory, antibacterial, antipyretic, diuretic, febrifuge, stimulant, antiseptic. Used for arthritis, rheumatic affections, cystitis and other urinary diseases, stomach and liver disorders, anorexia and debility.

Key application: Unopened leaf- buds externally for haemorrhoids, frostbite and sunburn. (German Commission E.)

The bark contains glycosides, salicin and populin, erisin and tannin (5-9%). Salicin, a bitter tonic and antiperiod- ic, is used like quinine in intermittent fever, also in rheumatism.... populus alba

Populus Nigra

Linn. var. italica Kochne.

Family: Salicaceae.

Habitat: North-western Himalaya at 900-3,700 m.

English: Black Lombardy Poplar.

Action: Bark and balsam from leaf bud— used for cold. Bark— depurative. Leaf bud—antiseptic, anti- inflammatory.

The bud exudate contains dimethyl- caffeic acid, which was found active against herpes simplex virus type 1.

A 50% ethanol extract of a mixture of flowers and buds showed 11% inhibition of enzymatic conversion of testosterone into 5 alpha-dihydrotesterone and 4-androstene-3,17-dione. The extract was partitioned between ethylac- etate and water and the resultant ethy- lacetate fraction contained the active compounds, pinobanksin, demethyl- quercetin and pinocembrin. It exhibited 15% inhibitory activity on the enzyme. Pinocembrin was the most potent, almost equal to estradiol, which was used as a control.

The bark of all Populus species contains, phenolic glycosides, salicin and populin (salicinbenzoate). Tannins are also present (5-9%).

Both salicin and populin cause elimination of uric acid. Salicin is antiperi- odic and is used like quinine in intermittent fever, also in coryza, rheumatism and neuralgia.... populus nigra

Porphyrias

A group of rare inherited ENZYME diseases in which disorders of the metabolic pathways leading to the synthesis of HAEM cause excessive production of haem precursors called PORPHYRINS by the bone marrow or liver. The excess porphyrins in the blood mainly affect the skin, causing PHOTOSENSITIVITY, or the central nervous system, causing various neuro-psychiatric disorders. Excess porphyrins can be detected in blood, urine and faeces. Usually porphyrias are genetically determined, but one form is due to alcoholic liver disease. The commonest form, porphyria cutanea tarda, affects up to 1 in 5,000 people in some countries. The British king, George III, suffered from porphyria, a disorder unrecognised in the 18th century.... porphyrias

Portability

Requirement in benefit plans that allow benefit rights to be transferred without waiting periods for persons moving between plans, regions or countries.... portability

Portal Circulation

This is a type of circulatory bypass used when substances in blood or fluid need to be kept out of the general flow. A portal system begins in capillaries and ends in capillaries, and nothing leaves it undocumented. The hypothalamus sends hormones into the portal system between it and the pituitary, and the pituitary responds to it by secreting its own hormones, but dissolving the hypothalamus ones. Blood that leaves the intestinal tract, spleen, and pancreas (partially) goes into the liver’s portal system and does not leave that organ until it has been thoroughly screened and altered.... portal circulation

Porter

(Latin) The doorkeeper... porter

Portia

(Latin) Piglike woman; an offering Portiah, Porsha, Porscha... portia

Portuguese Man-o’-war

The colloquial term used for the multi-tentacled hydrozoan colony of Physalia physalis common in the north Atlantic Ocean.... portuguese man-o’-war

Portulaca Quadrifida

Linn.

Family: Portulacaceae.

Habitat: Warmer parts of India, cultivated as a vegetable.

Ayurvedic: Laghu-lonikaa.

Siddha/Tamil: Siru Pasalai-keerai.

Action: Similar to P. oleracea. Used in asthma, cough, urinary discharges, inflammations and ulcers. A poultice of the herb is applied to haemorrhoids and erysipelas.... portulaca quadrifida

Portulaca Oleracea

Linn.

Family: Portulacaceae.

Habitat: All over India, cultivated as a vegetable.

English: Common Purslane.

Ayurvedic: Brihat Lonikaa, Lonaa, Loni, Ghoddhika, Ghotikaa, Upodika, Khursaa.

Unani: Khurfaa, Kulfaa.

Siddha/Tamil: Pulli-keerai, Parup- pukirai.

Action: Refrigerant (reduces body heat), mild spasmodic, diuretic, antiscorbutic. Used in scurvy and in diseases of liver, spleen, kidney and bladder; also in dysuria, stomatitis and dysentery. A paste of leaves is applied to swellings, erysipelas, burns and scalds. Seeds—diuretic, antidysenteric; applied externally to burns and scalds.

A crude protein-free extract of the herb contained l-nor-adrenaline, do- pamine and l-dopa, also catechol. (The fresh plant contained 2.5 mg/g l-nor- adrenaline in one sample.) The extract gave a strong pressor response when injected intravenously into anaesthetized dogs.

The oral administration of the ho- mogenates of P. oleracea reduced the blood sugar level of alloxan-diabetic rabbits to normal.

The extract of the leaves and stems reduced muscle tone in individuals suffering from spasticity and exhibited skeletal muscle relaxant activity both in vitro and in vivo. The extract produced dose-dependent negative in- otropic and chronotropic effects and pressor response on rat blood pressure.

The diuretic action of the herb is attributed to the presence of high percentage of potassium salts.

Dosage: Plant-125-400 mg powder; juice—1-20 ml (CCRAS.)... portulaca oleracea

Portulaca Tuberosa

Roxb.

Synonym: P. pilosa Linn.

Family: Portulacaceae.

Habitat: Peninsular India, near sea-coasts.

Ayurvedic: Bichhuu-buuti.

Folk: Jangali Gaajar (Gujarat), Sanjivani (Bihar).

Action: Leaves—an infusion is given internally in dysuria; externally applied to erysipelas. The herb shows diuretic, calculolythic, analgesic and antipyretic properties.

The aerial parts contain diterpe- noids, pilosanone A and B. leucorrhoea, dysmenorrhoea, arthritis, cramps, kidney stones, bleeding piles; as a mouth wash in pyrrhoea, gingivitis and sore throat.

Key application: In mild dismenor- rhoeal disorders; as a support for treatment of milder, nonspecific, acute diarrhoea and in light inflammation of the oral and pharyngeal mucosa. (German Commission E.)

The plant gave anthocyanins—cy- anidin and delphinidin. Aerial parts gave tannins (2-10%). The plant also gave choline, betaine, histidine, an essential oil and vitamin E.

The maximum amounts of tannins occur in the root stock (up to 17.5% on dry basis). The ethanolic and aqueous extract of the herb (1 : 5) contain 0.3 to 0.8% of tannin. The tannin fraction exhibited anti-mutagenic effect.

Potentilla fruticosa HK. (temperate Himalaya) is also used like Silverweed.

The flowers and young shoots contain flavonoids, quercetin, terniflorin, tribuloside and (-)-catechin. The plant also contains stigmasterol, beta-sitos- terol and campesterol; (-)-epicatechol gallate, (±)-catechol, (-)-epicatechol, (-)-epigallocatechol and (-)-epigallo- catechol gallate have been isolated from aerial parts.... portulaca tuberosa

Posala

(Native American) Born at the end of spring

Posalah, Posalla, Posallah... posala

Posh

(American) A fancy young woman Poshe, Posha... posh

Positive Ageing

See “healthy ageing”.... positive ageing

Positive Health

A state of health beyond an asymptomatic state. It usually includes the quality of life and the potential of the human condition. It may also include self-fulfilment, vitality for living and creativity. It is concerned with thriving rather than merely coping. See also “health”.... positive health

Positron-emission Tomography (pet)

See PET SCANNING.... positron-emission tomography (pet)

Possetting

The technical term used to describe the quite common habit of healthy babies to regurgitate, or bring up, small amounts of the meal they have just taken. Its name derives from possett, an 18th century drink made from porridge and sherry.... possetting

Post-acute Care

See “transitional care”.... post-acute care

Post-coital Test

A test for INFERTILITY. A specimen of cervical mucus, taken up to 24 hours after coitus (during the post-ovulatory phase of the menstrual cycle), is examined microscopically to assess the motility of the sperms. If motility is above a certain level, then sperms and mucus are not interacting abnormally – thus eliminating one cause of sterility.... post-coital test

Post-coital Contraception

Action taken to prevent CONCEPTION after sexual intercourse. The type of contraception may be hormonal, or it may be an intrauterine device (see below, and under CONTRACEPTION). Pregnancy after intercourse without contraception – or where contraception has failed as a result, for example, of a leaking condom – may be avoided with a course of ‘morning-after’ contraceptive pills. Such preparations usually contain an oestrogen (see OESTROGENS) and a PROGESTOGEN. Two doses should be taken within 72 hours of ‘unprotected’ intercourse. An alternative for the woman is to take a high dose of oestrogen on its own. The aim is to postpone OVULATION and to affect the lining of the UTERUS so that the egg is unable to implant itself.

Intrauterine contraceptive device (IUCD) This, in e?ect, is a form of post-coital contraception. The IUCD is a plastic shape up to 3 cm long around which copper wire is wound, carrying plastic thread from its tail. Colloquially known as a coil, it acts by inhibiting implantation and may also impair migration of sperm. Devices need changing every 3–5 years. Coils have generally replaced the larger, non-copper-bearing ‘inert’ types of IUCD, which caused more complications but did not need changing (so are sometimes still found in situ). They tend to be chosen as a method of contraception (6 per cent) by older, parous women in stable relationships, with a generally low problem rate.

Nevertheless, certain problems do occur with IUCDs, the following being the most common:

They tend to be expelled by the uterus in women who have never conceived, or by a uterus distorted by, say, ?broids.

ECTOPIC PREGNANCY is more likely.

They are associated with pelvic infection and INFERTILITY, following SEXUALLY TRANSMITTED DISEASES (STDS) – or possibly introduced during insertion.

They often produce heavy, painful periods (see MENSTRUATION), and women at high risk of these problems (e.g. women who are HIV positive [see AIDS/HIV], or with WILSON’S DISEASE or cardiac lesions) should generally be excluded – unless the IUCD is inserted under antibiotic cover.... post-coital contraception

Post-mortem Examination

Also called an autopsy (and less commonly, necropsy), this is an examination of a body to discover the causes of death. Such an examination is sometimes required by law. An unnatural death; a death occurring in suspicious circumstances; or a death when a doctor feels unable to complete a certi?cate about the cause – all must be reported to the CORONER (in Scotland, to the procurator ?scal). He or she may order an autopsy to be carried out as part of the inquiry into cause of death. Sometimes doctors may request the permission of relatives to perform a post-mortem so that they may discover something of value for the improvement of medical care. Relatives may refuse consent. (See also DEATH, CAUSES OF.)... post-mortem examination

Post-operative

The period after an operation, the patient’s condition after operation, or any investigations or treatment during this time.... post-operative

Post-partum

The term applied to anything happening immediately after childbirth: for example, postpartum haemorrhage. (See also PREGNANCY AND LABOUR.)... post-partum

Post-traumatic Stress Disorder (ptsd)

A term introduced to PSYCHIATRY in 1980 after the Vietnam War. It is one of several psychiatric disorders that can develop in people exposed to severe trauma, such as a major physical injury, participation in warfare, assault or rape, or any event in which there is major loss of life or a threat of loss of life. Most people exposed to trauma do not develop psychiatric disorder; however, some develop immediate distress and, occasionally, the reaction can be delayed for many months. Someone with PTSD has regular recurrences of memories or images of the stressful event (‘?ashbacks’), especially when reminded of it. Insomnia, feelings of guilt and isolation, an inability to concentrate and irritability may result. DEPRESSION is very common. Support from friends and family is probably the best management, but those who do not recover quickly can be helped by antidepressants and psychological treatments such as COGNITIVE BEHAVIOUR THERAPY. Over the past few years, PTSD has featured increasingly in compensation litigation.... post-traumatic stress disorder (ptsd)

Posy

(English) Resembling a bouquet of flowers; form of Josephine, meaning “God will add”

Posey, Posi, Posie, Posee, Pozy, Pozey, Pozi, Pozie, Pozee, Posea, Pozea... posy

Potassium-channel Activators

Drugs that have the ability to dilate ARTERIES and VEINS and are used to relieve pain in ANGINA of the HEART. Nicorandil is the main example.... potassium-channel activators

Potato

Image Magic, Healing... potato

Potentially Pathogenic Environmental Mycobacteria (ppem)

The atypical mycobacteria. The commonest PPEM to cause human disease is the Mycobacterium avium-intracellulare complex. PPEM differ from M. tuberculosis in their source (environmental or zoonotic), rate of growth, temperature of growth and ability to produce pigment on culture. Mostly infect immunologically compromised humans and the disease caused by some species may be clinicallyindistinguishable from true human tuberculosis.... potentially pathogenic environmental mycobacteria (ppem)

Potentially Preventable Adverse Outcome

Complication of a condition which may be modified or prevented with appropriate treatment.... potentially preventable adverse outcome

Potentilla Anserina

Linn.

Family: Rosaceae.

Habitat: Western Himalayas at altitudes of 2,100-4,800 m.

English: Silverweed.

Action: Astringent, antiinflammatory, antispasmodic, haemostatic. Used for diarrhoea,... potentilla anserina

Potentilla Arbuscula

D. Don.

Family: Rosaceae.

Habitat: Temperate Himalaya from Himachal Pradesh to Sikkim and the hills of Assam at 1,200-4,350 m.

Ayurvedic: Bajradanti (Kumaon and Garhwal). Potentilla fulgens HK. is also equated with Bajradanti.

Action: Rootstock—antidiar- rhoeal; used in tooth powders for strengthening gum and teeth.... potentilla arbuscula

Potentilla Nepalensis

Hook.

Family: Rosaceae.

Habitat: The Himalayas from Kashmir to Kumaon.

Folk: Ratanjot (substitute).

Action: Rootstocks—depurative; ash, mixed with oil, is applied to burns.

Unani: Baadiyaan-kohi, Karafs-e- kohi, Fitraasaaliyun (also equated with Petroselinum crispum Mill. Nym. ex auct. Kew.).

Folk: Komal.

Action: Root and fruit—diuretic, emmenagogue. An infusion of root is given for indigestion and irregular menses.

The roots and umbels yielded cou- marins and their glycosides. Osthol (7-methoxy-8-isop entenyl-coumarin), which occurs in the dried roots up to the extent of 3.6%, has been found to be a potent respiratory and circulatory stimulant in experimental animals. Its respirotonic effect was more marked than that of coramine, leptazol and caffeine.... potentilla nepalensis

Pothos Scandens

Linn.

Family: Araceae.

Habitat: Cultivated as an ornamental. Found in Bihar, North Bengal, Orissa, Western Ghats and Southwards.

Siddha/Tamil: Aanaparuga.

Action: Leaves—anti-inflammatory, antiseptic, antimicrobial. Applied to smallpox pustules. Root—bruised and fried in oil, applied to abscesses.... pothos scandens

Potina

(Latin) In mythology, goddess of children’s food and drink Potinah, Potyna, Potena, Poteena, Potiena, Poteina, Poteana... potina

Pott’s Disease

A traditional name often applied to the angular curvature of the spine which results from tuberculous disease. (See SPINE AND SPINAL CORD, DISEASES AND INJURIES OF.) The disease is named after Percivall Pott, an English surgeon (1714–88), who ?rst described the condition.... pott’s disease

Pott’s Fracture

A variety of fractures around the ankle, accompanied by a varying degree of dislocation of the ankle. In all cases the ?bula is fractured. Named after Percivall Pott, who suffered from this fracture and was the ?rst to describe it (see BONE, DISORDERS OF), it is often mistaken for a simple sprain of the ankle.... pott’s fracture

Pouchitis

A rare chronic in?ammatory disease in the ileal pouch, which remains after a patient has had intestinal resection because of INFLAMMATORY BOWEL DISEASE (IBD). Metronidazole and oral PROBIOTICS are e?ective treatments.... pouchitis

Poultices

(See also FOMENTATION.) Soft, moist applications to the surface of the body, generally used hot to soothe pain due to in?ammation and to promote resolution.... poultices

Pounamu

(Maori) A treasured gift... pounamu

Poupart’s Ligament

Also known as the inguinal ligament, it is the strong ligament lying in the boundary between the anterior abdominal wall and the front of the thigh.... poupart’s ligament

Poverty Level / Line

A minimum income level below which a person is officially considered to lack adequate subsistence and to be living in poverty. Poverty statistics are based on definitions developed by individual countries or constituencies.... poverty level / line

Prabhu

(Indian) A mighty woman... prabhu

Practice Guideline

Descriptive tool or standardized specification for care of an older person in a typical situation developed through a formal process that incorporates the best scientific evidence of effectiveness with expert opinion.... practice guideline

Pradeepta

(Indian) Feminine form of Pradeep; one who provides light Pradypta, Pradeapta, Pradeypta... pradeepta

Pragyata

(Hindi) One who is knowledgeable... pragyata

Prairie

(American) From the flatlands Prairi, Prairy, Prairey, Prairee, Prairea... prairie

Praise

(Latin) One who expresses admiration Prayse, Praize, Prayze, Praze, Praese, Praeze ... praise

Pramada

(Indian) One who is indifferent... pramada

Pramlocha

(Hindi) In Hinduism, a celestial nymph... pramlocha

Prangos Pabularia

Lindl.

Family: Umbelliferae; Apiaceae.

Habitat: Kashmir and Himachal Pradesh at altitudes of 1,8004,000 m.... prangos pabularia

Prarthana

(Hindi) One who prays... prarthana

Pratibha

(Hindi) An understanding woman Pratibhah, Pratybha, Pratybhah... pratibha

Pratima

(Indian) An image or icon Pratimah, Pratema, Pratyma, Prateema, Prateima, Pratiema, Prateama... pratima

Precia

(Latin) An important lady Preciah, Presha, Preshah, Pretia, Pretiah... precia

Precious

(American) One who is treasured Preshis, Preshys... precious

Precision

1 The quality of being sharply defined or stated. One measure of precision is the number of distinguishable alternatives from which a measurement was selected, sometimes indicated by the number of significant digits in the measurement. Another measure of precision is the standard error of measurement, the standard deviation of a series of replicate determinations of the same quantity. Precision does not imply accuracy. 2 In statistics, precision is defined as the inverse of the variance of a measurement or estimate.... precision

Precordial Region

The area on the centre and towards the left side of the chest, lying in front of the heart.... precordial region

Predictive Value

1 The statistic generated by dividing the number of true positives by the sum of the true positives and false positives. For example, the number of cases with truly good care divided by the sum of the cases with truly good care plus those cases classified with good care who did not receive it i.e. the likelihood that a person classified as the recipient of good care actually received good care. 2 In screening and diagnostic tests, the probability that a person with a positive test result is a true positive (i.e. does have the disease) is referred to as the “predictive value of a positive test”. The predictive value of a negative test is the probability that a person with a negative test does not have the condition or disease. The predictive value of a screening test is determined by the sensitivity and specificity of the test, and by the prevalence of the condition for which the test is used.... predictive value

Predictive Value Negative

The probability that a person with a negative test is free of the disease and is not a false negative.... predictive value negative

Predictive Value Positive

The probability that a person with a reactive test has the disease and is not a false reaction.... predictive value positive

Preeti

(Indian) One who loves and is loved Priti, Preetie, Pritie, Pritika, Priya, Preati... preeti

Preferred Breeding Sites

Sites suitable for egg-laying and satisfactory for all aquatic stages of development.... preferred breeding sites

Pregnancy And Labour

Pregnancy The time when a woman carries a developing baby in her UTERUS. For the ?rst 12 weeks (the ?rst trimester) the baby is known as an EMBRYO, after which it is referred to as the FETUS.

Pregnancy lasts about 280 days and is calculated from the ?rst day of the last menstrual period – see MENSTRUATION. Pregnancy-testing kits rely on the presence of the hormone beta HUMAN CHORIONIC GONADOTROPHIN (b HCG) which is excreted in the woman’s urine as early as 30 days from the last menstrual period. The estimated date of delivery can be accurately estimated from the size of the developing fetus measured by ULTRASOUND (see also below) between seven and 24 weeks. ‘Term’ refers to the time that the baby is due; this can range from 38 weeks to 41 completed weeks.

Physical changes occur in early pregnancy – periods stop and the abdomen enlarges. The breasts swell, with the veins becoming prominent and the nipples darkening. About two in three women will have nausea with a few experiencing such severe vomiting as to require hospital admission for rehydration.

Antenatal care The aim of antenatal care is to ensure a safe outcome for both mother and child; it is provided by midwives (see MIDWIFE) and doctors. Formal antenatal care began in Edinburgh in the 1930s with the recognition that all aspects of pregnancy – normal and abnormal – warranted surveillance. Cooperation between general practitioners, midwives and obstetricians is now established, with pregnancies that are likely to progress normally being cared for in the community and only those needing special intervention being cared for in a hospital setting.

The initial visit (or booking) in the ?rst half of pregnancy will record the history of past events and the results of tests, with the aim of categorising the patients into normal or not. Screening tests including blood checks and ultrasound scans are a routine part of antenatal care. The ?rst ultrasound scan is done at about 11 weeks to date the pregnancy, with a further one done at 20 weeks – the anomaly scan – to assess the baby’s structure. Some obstetric units will check the growth of the baby with one further scan later in the pregnancy or, in the case of twin pregnancies (see below), many scans throughout. The routine blood tests include checks for ANAEMIA, DIABETES MELLITUS, sickle-cell disease and THALASSAEMIA, as well as for the blood group. Evidence of past infections is also looked for; tests for RUBELLA (German measles) and SYPHILIS are routine, whereas tests for human immunode?ciency virus (see AIDS/ HIV below) and HEPATITIS are being o?ered as optional, although there is compelling evidence that knowledge of the mother’s infection status is bene?cial to the baby.

Traditional antenatal care consists of regular appointments, initially every four weeks until 34 weeks, then fortnightly or weekly. At each visit the mother’s weight, urine and blood pressure are checked, and assessment of fetal growth and position is done by palpating the uterus. Around two-thirds of pregnancies and labours are normal: in the remainder, doctors and midwives need to increase the frequency of surveillance so as to prevent or deal with maternal and fetal problems.

Common complications of pregnancy

Some of the more common complications of pregnancy are listed below.

As well as early detection of medical complications, antenatal visits aim to be supportive and include emotional and educational care. Women with uncomplicated pregnancies are increasingly being managed by midwives and general practitioners in the community and only coming to the hospital doctors should they develop a problem. A small number will opt for a home delivery, but facilities for providing such a service are not always available in the UK.

Women requiring more intensive surveillance have their management targeted to the speci?c problems encountered. Cardiologists will see mothers-to-be with heart conditions, and those at risk of diabetes are cared for in designated clinics with specialist sta?. Those women needing more frequent surveillance than standard antenatal care can be looked after in maternity day centres. These typically include women with mildly raised blood pressure or those with small babies. Fetal medicine units have specialists who are highly skilled in ultrasound scanning and specialise in the diagnosis and management of abnormal babies still in the uterus. ECTOPIC PREGNANCY Chronic abdominal discomfort early in pregnancy may be caused by unruptured ectopic pregnancy, when, rarely, the fertilised OVUM starts developing in the Fallopian tube (see FALLOPIAN TUBES) instead of the uterus. The patient needs hospital treatment and LAPAROSCOPY. A ruptured ectopic pregnancy causes acute abdominal symptoms and collapse, and the woman will require urgent abdominal surgery. URINARY TRACT INFECTIONS These affect around 2 per cent of pregnant women and are detected by a laboratory test of a mid-stream specimen of urine. In pregnancy, symptoms of these infections do not necessarily resemble those experienced by non-pregnant women. As they can cause uterine irritability and possible premature labour (see below), it is important to ?nd and treat them appropriately. ANAEMIA is more prevalent in patients who are vegetarian or on a poor diet. Iron supplements are usually given to women who have low concentrations of HAEMOGLOBIN in their blood (less than 10.5 g/dl) or who are at risk of becoming low in iron, from bleeding, twin pregnancies and those with placenta previa (see below). ANTEPARTUM HAEMORRHAGE Early in pregnancy, vaginal bleedings may be due to a spontaneous or an incomplete therapeutic ABORTION. Bleeding from the genital tract between 24 completed weeks of pregnancy and the start of labour is called antepartum haemorrhage. The most common site is where the PLACENTA is attached to the wall of the uterus. If the placenta separates before delivery, bleeding occurs in the exposed ‘bed’. When the placenta is positioned in the upper part of the uterus it is called an abruption. PLACENTA PRAEVIA is sited in the lower part and blocks or partly blocks the cervix (neck of the womb); it can be identi?ed at about the 34th week. Ten per cent of episodes of antepartum bleeding are caused by placenta previa, and it may be associated with bleeding at delivery. This potentially serious complication is diagnosed by ultrasound scanning and may require a caesarean section (see below) at delivery. INCREASED BLOOD PRESSURE, associated with protein in the urine and swelling of the limbs, is part of a condition known as PRE-ECLAMPSIA. This occurs in the second half of pregnancy in about 1 in 10 women expecting their ?rst baby, and is mostly very mild and of no consequence to the pregnancy. However, some women can develop extremely high blood pressures which can adversely affect the fetus and cause epileptic-type seizures and bleeding disorders in the mother. This serious condition is called ECLAMPSIA. For this reason a pregnant woman with raised blood pressure or PROTEIN in her urine is carefully evaluated with blood tests, often in the maternity day assessment unit. The condition can be stopped by delivery of the baby, and this will be done if the mother’s or the fetus’s life is in danger. If the condition is milder, and the baby not mature enough for a safe delivery, then drugs can be used to control the blood pressure. MISCARRIAGE Also called spontaneous abortion, miscarriage is the loss of the fetus. There are several types:

threatened miscarriage is one in which some vaginal bleeding occurs, the uterus is enlarged, but the cervix remains closed and pregnancy usually proceeds.

inevitable miscarriage usually occurs before the 16th week and is typi?ed by extensive blood loss through an opened cervix and cramp-like abdominal pain; some products of conception are lost but the developing placental area (decidua) is retained and an operation may be necessary to clear the womb.

missed miscarriages, in which the embryo dies and is absorbed, but the decidua (placental area of uterine wall) remains and may cause abdominal discomfort and discharge of old blood.

THERAPEUTIC ABORTION is performed on more than 170,000 women annually in England and Wales. Sometimes the woman may not have arranged the procedure through the usual health-care channels, so that a doctor may see a patient with vaginal bleeding, abdominal discomfort or pain, and open cervix – symptoms which suggest that the decidua and a blood clot have been retained; these retained products will need to be removed by curettage.

Septic abortions are now much less common in Britain than before the Abortion Act (1967) permitted abortion in speci?ed circumstances. The cause is the passage of infective organisms from the vagina into the uterus, with Escherichia coli and Streptococcus faecalis the most common pathogenic agents. The woman has abdominal pain, heavy bleeding, usually fever and sometimes she is in shock. The cause is usually an incomplete abortion or one induced in unsterile circumstances. Antibiotics and curettage are the treatment. INTRAUTERINE GROWTH RETARDATION describes a slowing of the baby’s growth. This can be diagnosed by ultrasound scanning, although there is a considerable margin of error in estimates of fetal weight. Trends in growth are favoured over one-o? scan results alone. GESTATIONAL DIABETES is a condition that is more common in women who are overweight or have a family member with diabetes. If high concentrations of blood sugar are found, e?orts are made to correct it as the babies can become very fat (macrosomia), making delivery more di?cult. A low-sugar diet is usually enough to control the blood concentration of sugars; however some women need small doses of INSULIN to achieve control. FETAL ABNORMALITIES can be detected before birth using ultrasound. Some of these defects are obvious, such as the absence of kidneys, a condition incompatible with life outside the womb. These women can be o?ered a termination of their pregnancy. However, more commonly, the pattern of problems can only hint at an abnormality and closer examination is needed, particularly in the diagnosis of chromosomal deformities such as DOWN’S (DOWN) SYNDROME (trisomy 21 or presence of three 21 chromosomes instead of two).

Chromosomal abnormalities can be de?nitively diagnosed only by cell sampling such as amniocentesis (obtaining amniotic ?uid – see AMNION – from around the baby) done at 15 weeks onwards, and chorionic villus sampling (sampling a small part of the placenta) – another technique which can be done from 12 weeks onwards. Both have a small risk of miscarriage associated with them; consequently, they are con?ned to women at higher risk of having an abnormal fetus.

Biochemical markers present in the pregnant woman’s blood at di?erent stages of pregnancy may have undergone changes in those carrying an abnormal fetus. The ?rst such marker to be routinely used was a high concentration of alpha-fetol protein in babies with SPINA BIFIDA (defects in the covering of the spinal cord). Fuller research has identi?ed a range of diagnostic markers which are useful, and, in conjunction with other factors such as age, ethnic group and ultrasound ?ndings, can provide a predictive guide to the obstetrician – in consultation with the woman – as to whether or not to proceed to an invasive test. These tests include pregnancy-associated plasma protein assessed from a blood sample taken at 12 weeks and four blood tests at 15–22 weeks – alphafetol protein, beta human chorionic gonadotrophin, unconjugated oestriol and inhibin A. Ultrasound itself can reveal physical ?ndings in the fetus, which can be more common in certain abnormalities. Swelling in the neck region of an embryo in early pregnancy (increased nuchal thickness) has good predictive value on its own, although its accuracy is improved in combination with the biochemical markers. The e?ectiveness of prenatal diagnosis is rapidly evolving, the aim being to make the diagnosis as early in the pregnancy as possible to help the parents make more informed choices. MULTIPLE PREGNANCIES In the UK, one in 95 deliveries is of twins, while the prevalence of triplets is one in 10,000 and quadruplets around one in 500,000. Racial variations occur, with African women having a prevalence rate of one in 30 deliveries for twins and Japanese women a much lower rate than the UK ?gure. Multiple pregnancies occur more often in older women, and in the UK the prevalence of fertility treatments, many of these being given to older women, has raised the incidence. There is now an o?cial limit of three eggs being transferred to a woman undergoing ASSISTED CONCEPTION (gamete intrafallopian transfer, or GIFT).

Multiple pregnancies are now usually diagnosed as a result of routine ultrasound scans between 16 and 20 weeks of pregnancy. The increased size of the uterus results in the mother having more or worse pregnancy-related conditions such as nausea, abdominal discomfort, backache and varicose veins. Some congenital abnormalities in the fetus occur more frequently in twins: NEURAL TUBE defects, abnormalities of the heart and the incidence of TURNER’S SYNDROME and KLINEFELTER’S SYNDROME are examples. Such abnormalities may be detected by ultrasound scans or amniocentesis. High maternal blood pressure and anaemia are commoner in women with multiple pregnancies (see above).

The growth rates of multiple fetuses vary, but the di?erence between them and single fetuses are not that great until the later stages of pregnancy. Preterm labour is commoner in multiple pregnancies: the median length of pregnancy is 40 weeks for singletons, 37 for twins and 33 for triplets. Low birth-weights are usually the result of early delivery rather than abnormalities in growth rates. Women with multiple pregnancies require more frequent and vigilant antenatal assessments, with their carers being alert to the signs of preterm labour occurring. CEPHALOPELVIC DISPROPORTION Disparity between the size of the fetus and the mother’s pelvis is not common in the UK but is a signi?cant problem in the developing world. Disparity is classi?ed as absolute, when there is no possibility of delivery, and relative, when the baby is large but delivery (usually after a dif?cult labour) is possible. Causes of absolute disparity include: a large baby – heavier than 5 kg at birth; fetal HYDROCEPHALUS; and an abnormal maternal pelvis. The latter may be congenital, the result of trauma or a contraction in pelvic size because of OSTEOMALACIA early in life. Disproportion should be suspected if in late pregnancy the fetal head has not ‘engaged’ in the pelvis. Sometimes a closely supervised ‘trial of labour’ may result in a successful, if prolonged, delivery. Otherwise a caesarean section (see below) is necessary. UNUSUAL POSITIONS AND PRESENTATIONS OF THE BABY In most pregnant women the baby ?ts into the maternal pelvis head-?rst in what is called the occipito-anterior position, with the baby’s face pointing towards the back of the pelvis. Sometimes, however, the head may face the other way, or enter the pelvis transversely – or, rarely, the baby’s neck is ?exed backwards with the brow or face presenting to the neck of the womb. Some malpositions will correct naturally; others can be manipulated abdominally during pregnancy to a better position. If, however, the mother starts labour with the baby’s head badly positioned or with the buttocks instead of the head presenting (breech position), the labour will usually be longer and more di?cult and may require intervention using special obstetric forceps to assist in extracting the baby. If progress is poor and the fetus distressed, caesarean section may be necessary. HIV INFECTION Pregnant women who are HIV positive (see HIV; AIDS/HIV) should be taking antiviral drugs in the ?nal four to ?ve months of pregnancy, so as to reduce the risk of infecting the baby in utero and during birth by around 50 per cent. Additional antiviral treatment is given before delivery; the infection risk to the baby can be further reduced – by about 40 per cent – if delivery is by caesarean section. The mother may prefer to have the baby normally, in which case great care should be taken not to damage the baby’s skin during delivery. The infection risk to the baby is even further reduced if it is not breast fed. If all preventive precautions are taken, the overall risk of the infant becoming infected is cut to under 5 per cent.

Premature birth This is a birth that takes place before the end of the normal period of gestation, usually before 37 weeks. In practice, however, it is de?ned as a birth that takes place when the baby weighs less than 2·5 kilograms (5••• pounds). Between 5 and 10 per cent of babies are born prematurely, and in around 40 per cent of premature births the cause is unknown. Pre-eclampsia is the most common known cause; others include hypertension, chronic kidney disease, heart disease and diabetes mellitus. Multiple pregnancy is another cause. In the vast majority of cases the aim of management is to prolong the pregnancy and so improve the outlook for the unborn child. This consists essentially of rest in bed and sedation, but there are now several drugs, such as RITODRINE, that may be used to suppress the activity of the uterus and so help to delay premature labour. Prematurity was once a prime cause of infant mortality but modern medical care has greatly improved survival rates in developing countries.

Labour Also known by the traditional terms parturition, childbirth or delivery, this is the process by which the baby and subsequently the placenta are expelled from the mother’s body. The onset of labour is often preceded by a ‘show’ – the loss of the mucus and blood plug from the cervix, or neck of the womb; this passes down the vagina to the exterior. The time before the beginning of labour is called the ‘latent phase’ and characteristically lasts 24 hours or more in a ?rst pregnancy. Labour itself is de?ned by regular, painful contractions which cause dilation of the neck of the womb and descent of the fetal head. ‘Breaking of the waters’ is the loss of amniotic ?uid vaginally and can occur any time in the delivery process.

Labour itself is divided into three stages: the ?rst is from the onset of labour to full (10 cm) dilation of the neck of the womb. This stage varies in length, ideally taking no more than one hour per centimetre of dilation. Progress is monitored by regular vaginal examinations, usually every four hours. Fetal well-being is observed by intermittent or continuous monitoring of the fetal heart rate in relation to the timing and frequency of the contractions. The print-out is called a cardiotocograph. Abnormalities of the fetal heart rate may suggest fetal distress and may warrant intervention. In women having their ?rst baby (primigravidae), the common cause of a slow labour is uncoordinated contractions which can be overcome by giving either of the drugs PROSTAGLANDIN or OXYTOCIN, which provoke contractions of the uterine muscle, by an intravenous drip. Labours which progress slowly or not at all may be due to abnormal positioning of the fetus or too large a fetus, when prostaglandin or oxytocin is used much more cautiously.

The second stage of labour is from full cervical dilation to the delivery of the baby. At this stage the mother often experiences an irresistible urge to push the baby out, and a combination of strong coordinated uterine contractions and maternal e?ort gradually moves the baby down the birth canal. This stage usually lasts under an hour but can take longer. Delay, exhaustion of the mother or distress of the fetus may necessitate intervention by the midwife or doctor. This may mean enlarging the vaginal opening with an EPISIOTOMY (cutting of the perineal outlet – see below) or assisting the delivery with specially designed obstetric forceps or a vacuum extractor (ventouse). If the cervix is not completely dilated or open and the head not descended, then an emergency caesarean section may need to be done to deliver the baby. This procedure involves delivering the baby and placenta through an incision in the mother’s abdomen. It is sometimes necessary to deliver by planned or elective caesarean section: for example, if the placenta is low in the uterus – called placenta praevia – making a vaginal delivery dangerous.

The third stage occurs when the placenta (or afterbirth) is delivered, which is usually about 10–20 minutes after the baby. An injection of ergometrine and oxytocin is often given to women to prevent bleeding.

Pain relief in labour varies according to the mother’s needs. For uncomplicated labours, massage, reassurance by a birth attendant, and a warm bath and mobilisation may be enough for some women. However, some labours are painful, particularly if the woman is tired or anxious or is having her ?rst baby. In these cases other forms of analgesia are available, ranging from inhalation of NITROUS OXIDE GAS, injection of PETHIDINE HYDROCHLORIDE or similar narcotic, and regional local anaesthetic (see ANAESTHESIA).

Once a woman has delivered, care continues to ensure her and the baby’s safety. The midwives are involved in checking that the uterus returns to its normal size and that there is no infection or heavy bleeding, as well as caring for stitches if needed. The normal blood loss after birth is called lochia and generally is light, lasting up to six weeks. Midwives o?er support with breast feeding and care of the infant and will visit the parents at home routinely for up to two weeks.

Some complications of labour All operative deliveries in the UK are now done in hospitals, and are performed if a spontaneous birth is expected to pose a bigger risk to the mother or her child than a specialist-assisted one. Operative deliveries include caesarean section, forceps-assisted deliveries and those in which vacuum extraction (ventouse) is used. CAESAREAN SECTION Absolute indications for this procedure, which is used to deliver over 15 per cent of babies in Britain, are cephalopelvic disproportion and extensive placenta praevia, both discussed above. Otherwise the decision to undertake caesarean section depends on the clinical judgement of the specialist and the views of the mother. The rise in the proportion of this type of intervention (from 5 per cent in the 1930s to its present level of over 23 per cent

P

of the 600,000 or so annual deliveries in England) has been put down to defensive medicine

– namely, the doctor’s fear of litigation (initiated often because the parents believe that the baby’s health has suffered because the mother had an avoidably di?cult ‘natural’ labour). In Britain, over 60 per cent of women who have had a caesarean section try a vaginal delivery in a succeeding pregnancy, with about two-thirds of these being successful. Indications for the operation include:

absolute and relative cephalopelvic disproportion.

placenta previa.

fetal distress.

prolapsed umbilical cord – this endangers the viability of the fetus because the vital supply of oxygen and nutrients is interrupted.

malpresentation of the fetus such as breech or transverse lie in the womb.

unsatisfactory previous pregnancies or deliveries.

a request from the mother.

Caesarean sections are usually performed using regional block anaesthesia induced by a spinal or epidural injection. This results in loss of feeling in the lower part of the body; the mother is conscious and the baby not exposed to potential risks from volatile anaesthetic gases inhaled by the mother during general anaesthesia. Post-operative complications are higher with general anaesthesia, but maternal anxiety and the likelihood that the operation might be complicated and di?cult are indications for using it. A general anaesthetic may also be required for an acute obstetric emergency. At operation the mother’s lower abdomen is opened and then her uterus opened slowly with a transverse incision and the baby carefully extracted. A transverse incision is used in preference to the traditional vertical one as it enables the woman to have a vaginal delivery in any future pregnancy with a much smaller risk of uterine rupture. Women are usually allowed to get up within 24 hours and are discharged after four or ?ve days. FORCEPS AND VENTOUSE DELIVERIES Obstetric forceps are made in several forms, but all are basically a pair of curved blades shaped so that they can obtain a purchase on the baby’s head, thus enabling the operator to apply traction and (usually) speed up delivery. (Sometimes they are used to slow down progress of the head.) A ventouse or vacuum extractor comprises an egg-cup-shaped metal or plastic head, ranging from 40 to 60 mm in diameter with a hollow tube attached through which air is extracted by a foot-operated vacuum pump. The instrument is placed on the descending head, creating a negative pressure on the skin of the scalp and enabling the operator to pull the head down. In mainland Europe, vacuum extraction is generally preferred to forceps for assisting natural deliveries, being used in around 5 per cent of all deliveries. Forceps have a greater risk of causing damage to the baby’s scalp and brain than vacuum extraction, although properly used, both types should not cause any serious damage to the baby.

Episiotomy Normal and assisted deliveries put the tissues of the genital tract under strain. The PERINEUM is less elastic than the vagina and, if it seems to be splitting as the baby’s head

moves down the birth canal, it may be necessary to cut the perineal tissue – a procedure called an episiotomy – to limit damage. This is a simple operation done under local anaesthetic. It should be done only if there is a speci?c indication; these include:

to hasten the second stage of labour if the fetus is distressed.

to facilitate the use of forceps or vacuum extractor.

to enlarge a perineum that is restricted because of unyielding tissue, perhaps because of a scar from a previous labour. Midwives as well as obstetricians are trained

to undertake and repair (with sutures) episiotomies.

(For organisations which o?er advice and information on various aspects of childbirth, including eclampsia, breast feeding and multiple births, see APPENDIX 2: ADDRESSES: SOURCES OF INFORMATION, ADVICE, SUPPORT AND SELF-HELP.)... pregnancy and labour

Pregnandiol

The excretion product of the hormone, PROGESTERONE, manufactured by the corpus luteum of the ovary (see OVARIES). Pregnandiol is excreted in the urine during the second half of the menstrual period, and its excretion rises steadily throughout pregnancy.... pregnandiol

Prema

(Hindi) One who is dearly loved Premah, Premma, Premmah... prema

Pregnancy Calendar - Week 4 Of Your Pregnancy

4 weeks pregnancy

"Pregnancy calendar" at 4th week: A miracle begins! Your baby, now consisting of a cell stack, is clinging to the walls of your uterus and starting to grow rapidly. Early pregnancy in this period, for example, nausea in pregnancy is extremely normal. Birth is a beautiful yet remote dream.

Your baby in 4 weeks pregnancy

Your baby is a seed of poppy seeds. By the end of the week your baby will be about 1 mm long. Once the fertilized egg is placed on the side of your uterus, it divides into cell layers and becomes an embryo from official care. These cells turn into the body of your baby during pregnancy, forming the nervous system, skeleton, muscles and organs.

Support system in formation

The disc-like organ, which connects your body systems to the baby's systems, begins to form and attaches to the uterine wall where the egg is placed. The umbilical cord comes out of one of the placenta. Amniotic fluid, which will stretch your baby during pregnancy, has begun to form in a circumscribing membrane sac.

Your 4th week pregnancy

As the fertilized egg gets into your uterus, you may experience some bleeding. This is known as implantation hemorrhage and is completely normal.

The results came

Thanks to the brand-new placenta-attacked hCG hormone and a pregnancy test at home after the first period you missed, you will get a positive result, but false negative results can also be seen. This hormone is the greatest cause of nausea or morning sickness that many pregnant women experience in the first three months. If you are not pregnant, but your pregnancy test at home is negative, you may need a doctor.... pregnancy calendar - week 4 of your pregnancy

Pregnancy Calendar - Week 5 Of Your Pregnancy

5-week pregnancy

"Pregnancy calendar" at week 5: Your baby's brain is developing. You may feel fears about pregnancy and birth during this period. These emotional fluctuations are normal, do not worry at all!

Baby for 5 weeks gestation

Your baby, between 1 and 2.5 mm, is a small orange seed.

Installation ready

The placenta and the umbilical cord that begins to form have begun to work to transfer the necessary nutrients from your body to the body of the baby. Oxygen, amino acids, fats and sugars all play a critical role in a healthy development.

Some basics

Some of Baby's cells turn into a nerve pathway that will form the backbone and brain. An incorrectly formed nerve pathway can lead to a complication called "discrete spine", a condition in which the spinal cord is not completely closed. Your best weapon against spinal cord birth defects is to take at least 400 micrograms of folic acid every day.

Heart start

The heart is now a single tube with a few irregular shots. With each passing week these shots will become more regular.

Your 5th week pregnancy

Emotional ocean

You may be very happy because you are pregnant, worried about everything being normal, fearful about birth, or not being sure of yourself as a mothers of mothers. Do not worry about it! All of these feelings are completely normal. By weekly calculation of pregnancy and birth calculation, keep your head busy dreaming about the birth of your baby.

Careful maintenance

At this stage of the pregnancy period, menstrual cramps and back pain are common. Take a break by taking a warm bath, listening to soothing music or taking a nap. Watch your food and if you have not done so, stop smoking, drinking alcohol or taking medication. All of this is harmful to your baby.... pregnancy calendar - week 5 of your pregnancy

Premium

The amount paid or payable, often in instalments, by an insured person or policy holder to an insurer or third party payer for insurance coverage under an insurance policy. Premiums are paid for coverage whether benefits are used or not.... premium

Premlata

(Hindi) A loving woman Premlatah, Premlatta, Premlatia, Premlatea... premlata

Prentice

(English) A student; an apprentice Prentyce, Prentise, Prentyse... prentice

Prepatent Period

Time of infection (bite) to the first finding of the organism (eg, malaria parasite) in the bloodstrea m, i.e. from the time of infection to time when first diagnostic stages can be detected.... prepatent period

Prepayment

Fee paid by a potential consumer of services in anticipation of services that may be required.... prepayment

Premna Herbacea

Roxb.

Synonym: Pygmaeopremna herbacea Moldenke.

Family: Verbenaceae.

Habitat: The sub-tropical Himalayas and in Assam, extending southwards through West Bengal, Bihar, Orissa into Deccan Peninsula. Roots are usually confused with those of Clerodendrum serratum and are sold as Bhaarangi.

Siddha/Tamil: Siru Thekku.

Folk: Gethiaa, Ghantu Bhaarangi. Baaman-haati (Bengal). Fruits are known as Bhuumi-jambu, Phin Jaamun. The root is known as Bhaarangamuula; in Andhra Pradesh, Gandu Bhaarangi.

Action: Root and leaves—given in asthma, rheumatism.

The root contains several diterpe- noids. Quinonemethide (bharangin) is reported from the plant. controlling the activity of the adreno- corticotropic hormone.

Dosage: Leaf, root bark—50- 100 ml decoction, powder—1-3 g. (CCRAS.)... premna herbacea

Premna Integrifolia

Linn.

Synonym: P. obtusifolia R. Br. P. corymbosa auct. non Rottl. & Willd.

Family: Verbenaceae.

Habitat: Indian and Andaman Coasts, plains of Assam and Khasi hills.

English: Headache tree.

Ayurvedic: Agnimantha (Kerala), Shriparni, Jayee, Ganikaarikaa, Vaataghni.

Siddha/Tamil: Munnai

Folk: Agethaa, Ganiyaari.

Action: Carminative, galactagogue. The tender plant is used for neuralgia and rheumatism. A decoction of leaves is used for flatulence and colic.

Aqueous extracts of the plant showed a powerful action on the uterus and gout of the experimental animals, causing a marked increase in their activity.

The leaves contain an isoxazole alkaloid premnazole, which was found to reduce granuloma formation in rats (34.62%), its activity was comparable to phenylbutazone (35-36%).

Premnazole also reduced GPT and GOT in serum and liver. Studies suggest that premnazole acts probably by

Family: Verbenaceae.

Habitat: Peninsular India, Bihar, West Bengal and North-eastern India.

English: Dusky Fire Brand Bark.

Ayurvedic: Agnimantha (var.).

Siddha/Tamil: Pachumullai, Erumai munnai.

Folk: Agethu (var.).

Action: Leaves—diuretic, spasmolytic. Stem bark—hypoglycaemic.

The leaves gave a furanoid, prem- nalatin, and flavone glycosides. The stem bark gave iridoid glucosides and geniposidic acid.

Premna latifolia var. mucronata C. B. Clarke and Premna barbata Wall. are known as Bakaar and Basota (in Garh- wal). These have been equated with the classical herb Vasuhatta.... premna integrifolia

Prescilian

(Spanish) A fashionable woman Presciliann, Prescilianne... prescilian

Prescription Drugs

All those medications requiring written notification from a doctor to a pharmacist before they can be dispensed.... prescription drugs

Presencia

(Spanish) One who presents herself well

Presenciah, Presencea, Presenceah, Presenciya, Presenciyah... presencia

Premna Tomentosa

Willd.

Cornulia corymbosa

Family: Verbenaceae.

Habitat: Peninsular India and Bihar up to 1,200 m.

English: Bastard Teak.

Ayurvedic: Agnimanth (var.).

Siddha/Tamil: Kolakottathekku pinari, Pondanganari.

Folk: Gineri (var.).

Action: Bark and essential oil of root—used in stomach disorders. Leaf—diuretic, vulnerary; prescribed as a tonic after child birth; used in dropsical affections. Pounded leaves—vulnerary.

The heartwood gave apigenin derivatives. The leaves gave essential oil containing d-and dl-limonene, beta- caryophyllene a sesquiterpene hydrocarbon, a diterpene hydrocarbon and a sesquiterpene tertiary alcohol.

The roots and rhizomes of P. veris and P. elatior contain a saponin, yielding a sapogenin, primulagenin A. A fla- vonol glycoside named primulaflavo- noloside has been reported in the flowers of P. veris. The root of P. veris are considered as a substitute for Senega (Polygala senega) roots.

Anthocyanidins have been detected in most of the Primula species, also a highly toxic allergenic substance, primin, in the leaves and glandular hairs. The floral and foliar parts of the different genotypes showed presence of kaempferol, quercetin and myricetin.... premna tomentosa

Prenatal Screening Or Diagnosis

Prenatal screening of fetal abnormalities may be the result of screening tests carried out on most or all pregnant women, or as the result of speci?c diagnostic tests performed to detect speci?c conditions. Prenatal diagnosis is important as it will identify babies who might need medical or surgical treatment before or soon after birth. In addition, it may also detect severe abnormalities for which parents might decide to have a therapeutic ABORTION.

ULTRASOUND scanning is probably the most widely used diagnostic tool in obstetric practice. It can detect structural abnormalities such as SPINA BIFIDA and CLEFT PALATE and even cardiac and renal problems. A series of scans can assess whether the baby is growing at a normal rate; ultrasound may also be used to assist with other diagnostic tests (e.g. AMNIOCENTESIS – see below).

Tests on the mother’s blood can also diagnose fetal abnormalities. Alphafetoprotein (AFP) is produced by babies and ‘leaks’ into the AMNIOTIC FLUID and is absorbed by the mother. In spina bi?da and other neural-tube defects there is increased leakage of AFP, and a blood test at 16 weeks’ gestation can detect a raised level which suggests the presence of these abnormalities.

The triple test, also performed at 16 weeks, measures AFP and two hormones – HUMAN CHORIONIC GONADOTROPHIN and unconjugated OESTRADIOL – and is used in diagnosing DOWN’S (DOWN) SYNDROME.

Amniocentesis involves inserting a needle through the mother’s abdominal wall into the uterus to remove a sample of amniotic ?uid at 16–18 weeks. Examination of the ?uid and the cells it contains is used in the diagnosis of Down’s syndrome and other inherited disorders. The test carries a small risk of miscarriage.

Chorionic villus sampling may be used to diagnose various inherited conditions. A small amount of tissue from the developing PLACENTA is removed for analysis: this test has the advantages of having a lower incidence of miscarriage than amniocentesis and is carried out at an earlier stage (9–13 weeks).

Analysis of a blood sample removed from the umbilical cord (cordocentesis) may diagnose infections in the uterus, blood disorders or inherited conditions.

Direct observation of the fetus via a viewing instrument called a fetoscope is also used diagnostically and will detect structural abnormalities.

Most tests have a recognised incidence of false positive and negative results and are therefore usually cross-checked with another test. Counselling of the parents about prenatal tests is important. This allows them to make an informed choice which may not necessarily involve terminating the pregnancy if an abnormality is found. (See PREGNANCY AND LABOUR.)... prenatal screening or diagnosis

Presenile

Describing the condition of premature AGEING. The mental and physical faculties are adversely affected in presenility to an extent that does not usually occur until old age. (See also DEMENTIA.)... presenile

Presley

(English) Of the priest’s town Presly, Presle, Presli, Preslie, Preslee, Presleigh, Preslea, Prezley, Prezly, Prezli, Prezlie, Prezlee, Prezleigh, Prezlea... presley

Prevalence Rate

quotient using as the numerator, the number of persons sick or portraying a certain condition, in a stated population, at a particular time, regardless of when that illness or condition began, and as the denominator, the number of persons in the population in which they occurred.... prevalence rate

Prevalence Study

See “cross-sectional study”.... prevalence study

Prevention

This is aimed at promoting health, preserving health and restoring health when it is impaired and to minimize suffering and distress. There are various levels of prevention:... prevention

Preventive Care

Care that has the aim of preventing disease or its consequences. It includes health care programmes aimed at warding off illnesses, early detection of disease, and inhibiting further deterioration of the body.... preventive care

Pribislava

(Polish) One who is glorified Pribislavia, Pribislavea, Pribislawa, Pribka, Pribuska... pribislava

Prima

(Latin) The firstborn child Primalia, Primma, Pryma, Primia, Primea, Preema, Preama... prima

Primary Cancer

An original cancer still at the site at which it started to grow.... primary cancer

Primary Health Care

Sometimes called primary medical care, this is the care provided by a GENERAL PRACTITIONER (GP) – traditionally entitled the family doctor – or other health professionals who have ?rst contact with a patient needing or wanting medical attention. In the NHS, the primary health-care services include those provided by the general, dental, ophthalmic and pharmaceutical services as well as the family doctor service. Community health services provided outside the hospitals also o?er some primary health care.... primary health care

Primary Study

An investigation that collects original (primary) data from subjects, e.g. randomized controlled trials, observational studies, series of cases, etc. See “secondary data analysis”.... primary study

Primavera

(Spanish) Born during spring... primavera

Primola

(Latin) Resembling a primrose Primolah, Primolia, Primoliah, Primolea, Primoleah... primola

Primordial Prevention

Actions and measures that inhibit the emergence and establishment of environmental, economic, social and behavioural conditions, cultural patterns of living, etc., known to increase the risk of disease.... primordial prevention

Primula Vulgaris

Huds.

Primula denticulata Sm.

Family: Primulaceae.

Habitat: Temperate Himalayas from Kashmir to Bhutan and in Khasi and Jaintia hills at 1,500 m.

Folk: Keechey (Tibet).

Action: Root—powder used for killing leeches. Flowers—eaten in salad.

The whole plant contains several tri- terpenoid saponins.

Primula veris Linn., synonym P officinalis Hill and P. elatior Hill are grown in Indian gardens.

Key application: Primula veris, P. elatior Hill—the flower and the root in catarrhs of the respiratory tract. (German Commission E, ESCOP.) Contraindicated in gastritis and gastric ulcer. (ESCOP.)

Synonym: P. acaulis Hill.

Family: Primulaceae.

Habitat: Sub-Himalayan region.

English: Primrose (Evening Primrose is equated with Oenothera biennis), Cowslip.

Unani: Nakhud. (Also equated with Cicer arietinum by National Formulary of Unani Medicine.)

Action: Plant—anti-inflammatory, vulnerary, vermifuge, emetic. Used only externally.

The plant gave phenolic glycosides, flavonoids, saponins.... primula vulgaris

Princess

(English) A highborn daughter; born to royalty

Princessa, Princesa, Princie, Princi, Princy, Princee, Princey, Princea, Prinsess, Prinscella, Prinscelle, Princella, Princelle, Prinscilla... princess

Principal Diagnosis

The medical condition that is ultimately determined to have caused a person’s need for medical care. The principal diagnosis is used to assign every person to a diagnosis-related group. This diagnosis may differ from the admitting and major diagnoses. See also “diagnosis”.... principal diagnosis

Prions

Formally known as the “slow viruses”. Prions are in reality transmissible abnormal proteins infecting the CNS. They cause such human diseases as Kuru, Creutzfeld-Jacob Disease (CJD), bovine spongiform encephalitis (‘mad cow disease’) – all of which are characterised by their ext remely long incubation period.... prions

Prior Authorization

A requirement imposed by a third party payer under many systems of utilization review in which a provider must justify, before a peer review committee, insurance company representative or state agent, the need to deliver a particular service to a person before actually providing the service in order to receive reimbursement.... prior authorization

Prioritization

Arranging or dealing with in order of importance.... prioritization

Prisca

(Latin) From an ancient family Priscah, Priska, Priscca, Priscka, Piroska, Pirosca, Piroscka, Piri... prisca

Priscilla

(Latin) Form of Prisca, meaning “from an ancient family” Priscella, Precilla, Presilla, Prescilla, Prisilla, Prisella, Prissy, Prissi, Prissie, Prissey, Prissee, Prissea, Prisy, Pris, Priss... priscilla

Prisisima

(Spanish) Having great wisdom Prisima... prisisima

Prisma

(Hindi) One who is cherished Prismah, Prizma, Prizmah... prisma

Pristina

(Latin) One who is unspoiled Prystina, Pristeena, Prysteena, Pristeana, Prysteana, Pristyna, Prystyna, Pristiena, Prystiena, Pristeina, Prysteina... pristina

Private Health Care

The provision of medical and dental care to patients who pay for the care either directly, through private medical insurance, or through employer-funded private insurance. In the UK, most patients are treated and cared for by the community- or hospital-based NHS. Although not forbidden to do so, few NHS general practitioners see private patients. NHS consultants are – within certain prescribed circumstances – allowed to treat private patients and many, especially surgeons, do so; but consultations and treatment are usually done on private-health premises. Some NHS hospitals have private facilities attached, but most private care is carried out in separate, privately run clinics and hospitals.

Certain specialties – for example, orthopaedic and reconstructive/cosmetic surgery and mental health – attract more private patients than others, such as paediatrics or medicine for the elderly. The standards of clinical care are generally the same in the two systems, but private patients can see the specialist of their choice at a time convenient to them. Waiting times for consultations and treatment are short and, when in hospital, private patients usually have their own room, telephone, TV, open visiting hours, etc.

A substantial proportion of private medical-care services are those provided for elderly people requiring regular nursing care and some medical supervision. The distinction between residential care and nursing care for the elderly is often blurred, but the government policy of providing means-tested state funding only for people genuinely needing regular nursing care – a system operated by local-authority social-service departments in England and Wales – has necessitated clearer de?nitions of the facilities provided for the elderly by private organisations. The strict criteria for state support (especially in England), the budget-conscious approach of local authorities when negotiating fees with private nursing homes, and the fact that NHS hospital trusts also have to pay for some patients discharged to such homes (to free-up hospital beds for new admissions) have led to intense ?nancial pressures on private facilities for the elderly. This has caused the closure of many homes, which, in turn, is worsening the level of BED-BLOCKING by elderly patients who do not require hospital-intensity nursing but who lack family support in the community and cannot a?ord private care.... private health care

Private Health Insurance

Privately organized health insurance that is based on estimation of probable population risks, and that provides either total or partial indemnity of medical expenses.... private health insurance

Probability (p Value)

The likelihood that an event will occur. When looking at differences between data samples, statistical techniques are used to determine if the differences are likely to reflect real differences in the whole group from which the sample is drawn, or if they are simply the result of random variation in the samples. It is the probability that a test statistic would be as extreme as, or more extreme than that observed if the null hypothesis were true. The letter P, followed by the abbreviation n.s. (not significant) or by the symbol < (less than) and a decimal notation such as 0.01, 0.05, is a statement of the probability that the difference observed could have occurred by chance, if the groups are really alike, i.e. under the null hypothesis. Although investigators may choose their own significance levels in most studies, a result whose probability value is less than 5% (P<0.05) or 1% (P<0.01) is considered sufficiently unlikely to have occurred by chance to justify the designation “statistically significant”. For example, a probability (or P value) of 1% indicates that the differences observed would have occurred by chance in one out of a hundred samples drawn from the same data.... probability (p value)

Procainamide Hydrochloride

A derivative of PROCAINE, used to treat certain cardiac arrythmias (irregularities in the heartbeat).... procainamide hydrochloride

Procercoid

The second stage larva of pseudophyllidean tapeworms which bears six hooks near the posterior end.... procercoid

Prochora

(Latin) One who guides others Prochorah, Prochoria, Prochoriah, Prochorea, Prochoreah... prochora

Procne

(Greek) In mythology, an Athenian princess... procne

Procreant

The drug which begets... procreant

Proctoptosis

Prolapse of the rectum... proctoptosis

Prodromal Period

Premonitory period; indicating the approach of a disease.... prodromal period

Prodromata

A term applied to the earliest symptoms of a disease, or those which give warning of its presence.... prodromata

Productivity

The ratio of the quantity and quality of units produced per unit of time.... productivity

Professional Accountability

Conduct in accordance with good practice as recognized and endorsed by a professional society.... professional accountability

Professional Liability Insurance

Liability insurance to protect professionals for loss or expense resulting from claims arising from mistakes, errors or omissions committed or alleged to have been committed by the insured in his professional activities.... professional liability insurance

Professional Self-regulation

The enforcement of certain rules of conduct among its members by a professional community.... professional self-regulation

Profile Analysis Or Profiling

Review and analysis of practice profiles to identify and assess patterns of health care services.... profile analysis or profiling

Proglottid

Single segment of a tapeworm.... proglottid

Programme

An organized aggregate of activities directed towards the attainment of defined objectives and targets which are progressively more specific than the goals to which they contribute. See “health programme”; “care programme”.... programme

Programme Budgeting

The process of making resources available to attain the objectives of programmes. Programme budgeting differs from ordinary budgeting in that the emphasis is on the results to be achieved rather than on unconnected budgetary items. The objectives and targets of the programme are defined clearly and, in order to attain them, the resources required are grouped together, those who will receive them specified, and their sources determined.... programme budgeting

Programme Evaluation / Review

The systematic assessment of the relevance, adequacy, progress, efficiency, effectiveness and impact of a programme.... programme evaluation / review

Programme Management

A system of management which involves the integration of planning, resourcing and evaluation processes to achieve stated outcomes.... programme management

Proguanil Hydrochloride

A synthetic antimalarial drug usually used with CHLOROQUINE to prevent infection with MALARIA. Occasionally the drug is used to treat uncomplicated falciparum malaria in combination with atovaquone.... proguanil hydrochloride

Project

A unique endeavour with a beginning and an end to be completed by one or more people within the constraints of time, budget and quality; a problem scheduled for solution.... project

Promethazine Hydrochloride

A widely used antihistamine drug with a prolonged action and a pronounced sedative e?ect. (See ANTIHISTAMINE DRUGS.)... promethazine hydrochloride

Promethazine Theoclate

A drug that is widely used in the alleviation or prevention of sea-sickness (see MOTION (TRAVEL) SICKNESS).... promethazine theoclate

Promise

(American) A faithful woman Promice, Promyse, Promyce, Promis, Promiss, Promys, Promyss... promise

Prompt Attention

The principle that those needing care are able to access it speedily.... prompt attention

Proportion

A number ranging between 0 and 0.1 calculated by dividing the number of subjects having a certain characteristic by the total number of subjects. See also “percentage”.... proportion

Proportional Mortality Rate (pmr)

A measure of the relative contribution to total mortality by a specific cause and these are expressed as number of deaths assigned to the state cause in a calendar year per 1000 total deaths in that year.... proportional mortality rate (pmr)

Propranolol Hydrochloride

One of the BETA-ADRENOCEPTOR-BLOCKING DRUGS, propranolol hydrochloride is used in the treatment of ANGINA PECTORIS, myocardial infarction (see under HEART, DISEASES OF), certain abnormal rhythms of the heart, and high blood pressure (HYPERTENSION). It also prevents attacks of MIGRAINE, and is used for certain anxiety states – particularly those associated with unpleasant bodily sensations, such as palpitations. (See also ADRENERGIC RECEPTORS.)... propranolol hydrochloride

Proprioceptors

Sensory nerve endings in the muscles, tendons and joints which signal to the brain their position relative to the outside world and the state of contraction of the muscle. During movement, a regular ?ow of information to the brain from the proprioceptors, the eyes and ears ensures that actions are coordinated and the body’s balance maintained.... proprioceptors

Proserpina

(Latin) In mythology, goddess of the underworld Proserpinah, Proserpyna, Proserpeena, Proserpiena, Proserpeana... proserpina

Prosopis Chilensis

Stuntz.

Synonym: Prosopis juliflora DC.

Family: Mimosaceae.

Habitat: Argentine, Arid, Mexican, Peruvian and Australian species have been introduced into India.

English: Mesquite.

Folk: Khejaraa, Vilaayati Kikar, Kaabuli Kikar.

Action: Gum—inferior to Gum arabic. The dry wood contains 0.9, bark 3.0-8.4, and roots 6-7% tannin.

The leaves contain piperidine alkaloids, juliprosinene, juliflorinine and N-methyljuliforidine. Other alkaloids present in the leaves are juliprosine, isojuliprosine, juliflorine, julifloricine and julifloridine.

A mixture of alkaloids containing mainly juliprosine and isojuliprosine showed significant antifungal activity against dermatophytes (comparable to griseofulvin).

The alkaloid fraction also showed broad spectrum bactericidal action against both Gram-positive and Gramnegative bacteria (comparable to antibiotics like penicillin, streptomycin, ampicillin, sulphamethoxazole and te- tracycline).

Significant activity of juliflorine against fungi and bacteria, and that of julifloricine against bacteria has also been reported.

The fruit gave a flavone glycoside, patulitrin which exhibited cytotoxic activity.... prosopis chilensis

Prosopis Stephaniana

Kunth.

Family: Mimosaceae.

Habitat: Parts of Punjab and Gujarat.

Ayurvedic: Samudra-shami, Shami (var.).

Folk: Khejaraa (var.)

Action: Pods and roots—astringent, styptic, antidysenteric.... prosopis stephaniana

Prospective Payment System

A system whereby reimbursement rates are set for a given period of time prior to the circumstances giving rise to actual reimbursement claims.... prospective payment system

Prospera

(Latin) One who is fortunate Prosperia, Prosper, Prosperea, Prosperous... prospera

Prosopis Spicigera

Linn.

Synonym: P. cineraria Druce.

Family: Mimosaceae.

Habitat: Dry and acrid regions of India.

Ayurvedic: Shami, Tungaa, Keshahantri, Shankuphalaa.

Siddha/Tamil: Kalisam.

Action: Pod—astringent, pectoral, demulcent. Bark—anti- inflammatory, antirheumatic. Flower—administered to prevent miscarriage.

The stem bark contains vitamin K, n-octacosyl acetate, the long chain aliphatic acid. Presence of glucose, rhamnose, sucrose and starch is also reported.

A cytotoxic principle, patulibin, has been isolated from flowers.

Dosage: Leaf, fruit—3-5 g powder, 50-100 ml decoction. (CCRAS.)... prosopis spicigera

Prostaglandins

Those natural substances, so-called because they were ?rst discovered in the SEMEN and thought to arise in the PROSTATE GLAND, are a group of fatty-acid substances with a wide range of activity. The richest known source is semen, but they are also present in many other parts of the body. Their precise mode of action is not yet clear, but they are potent stimulators of muscle contraction and they are also potent VASODILATORS. They cause contraction of the UTERUS and have been used to induce labour (see PREGNANCY AND LABOUR); they are also being used as a means of inducing therapeutic abortions (see ABORTION).

Prostaglandins play an important part in the production of PAIN, and it is now known that ASPIRIN relieves pain by virtue of the fact that it prevents, or antagonises, the formation of certain prostaglandins. In addition, they play some, although as yet incompletely de?ned, part in producing in?ammatory changes. (See INFLAMMATION; NON-STEROIDAL ANTIINFLAMMATORY DRUGS (NSAIDS).)

Thus prostaglandins have potent biological effects, but their instability and rapid metabolism make them short-acting. They are produced but not stored by most living cells and act locally. The two most important prostaglandins are prostacycline and thromboxane: prostacycline is a vasodilator and an inhibitor of platelet aggregation; thromboxanes have the opposite effects and cause vasoconstriction and platelet aggregation. The NSAIDs act by blocking an ENZYME called cyclo-oxygenase which converts arachidonic acid to the precursors of the various prostaglandins. Despite their potent pharmacological properties, the role of prostaglandins in current therapeutics is limited and controversial. They have been used most successfully as an inhibitor of platelet aggregation in extra-corporeal haemoperfusion systems. The problems with the prostacyclines is that they have to be given intravenously as they are inactive by mouth, and continuous infusion is required because the drug is rapidly eliminated with a half-life of minutes. Side-effects tend to be severe because the drug is usually given at the highest dose the patient can tolerate. The hope for the future lies in the exploitation of the compound to generate, synthetically, stable orally active prostacycline analogues which will inhibit platelet aggregation and hence thrombotic events, and yet have minimal effects on the heart and blood vessels.... prostaglandins

Prostate

This is a walnut-sized gland that surrounds the beginning of the urethra in men. It secretes the alkaline transport fluid that mixes with sperm from the testes to form semen. The prostate needs adequate anabolic steroid stimulation for its health and growth, especially testosterone. Because of diminished healthy hormone levels, pelvic congestion, and decreased blood (and hormone) circulation, or because of sexually transmitted or urinary tract infections, a male may get prostatitis. (See BPH.)... prostate

Prostatis

See under PROSTATE GLAND, DISEASES OF.... prostatis

Protease Inhibitors

A new group of drugs which, in combination with antiviral agents, are used to treat AIDS (see AIDS/HIV). They inhibit the activity of PROTEASE, an enzyme produced by HIV, and which breaks down proteins. The drugs have recently been introduced: those in use are indinavir, nel?navir, ritonavir and saquinavir.... protease inhibitors

Prostate Gland, Diseases Of

Disease of the PROSTATE GLAND can affect the ?ow of URINE so that patients present with urological symptoms.

Prostatitis This can be either acute or chronic. Acute prostatitis is caused by a bacterial infection, while chronic prostatitis may follow on from an acute attack, arise insidiously, or be non-bacterial in origin.

Symptoms Typically the patient has pain in the PERINEUM, groins, or supra pubic region, and pain on EJACULATION. He may also have urinary frequency, and urgency.

Treatment Acute and chronic prostatitis are treated with a prolonged course of antibiotics. Patients with chronic prostatitis may also require anti-in?ammatory drugs, and antidepressants.

Prostatic enlargement This is the result of benign prostatic hyperplasia (BPH), causing enlargement of the prostate. The exact cause of this enlargement is unknown, but it affects 50 per cent of men between 40 and 59 years and 95 per cent of men over 70 years.

Symptoms These are urinary hesitancy, poor urinary stream, terminal dribbling, frequency and urgency of urination and the need to pass urine at night (nocturia). The diagnosis is made from the patient’s history; a digital examination of the prostate gland via the rectum to assess enlargement; and analysis of the urinary ?ow rate.

Treatment This can be with tablets, which either shrink the prostate – an anti-androgen drug such as ?nasteride – or relax the urinary sphincter muscle during urination. For more severe symptoms the prostate can be removed surgically, by transurethral resection of prostate (TURP), using either electrocautery or laser energy. A new treatment is the use of microwaves to heat up and shrink the enlarged gland.

Cancer Cancer of the prostate is the fourth most common cause of death from cancer in northern European males: more than 10,000 cases are diagnosed every year in the UK and the incidence is rising by 3 per cent annually.

Little is known about the cause, but the majority of prostate cancers require the male hormones, androgens, to grow.

Symptoms These are similar to those resulting from benign prostatic hypertrophy (see above). Spread of the cancer to bones can cause pain. The use of a blood test measuring the amount of an ANTIGEN, PROSTATE SPECIFIC ANTIGEN (PSA), can be helpful in making the diagnosis – as can an ULTRASOUND scan of the prostate.

Treatment This could be surgical, with removal of the prostate (either via an abdominal incision, total prostatectomy, or transurethrally), or could be by radiotherapy. In more advanced cancers, treatment with anti-androgen drugs, such as cyprotexone acetate or certain oestrogens, is used to inhibit the growth of the cancer.... prostate gland, diseases of

Prostate Specific Antigen (psa)

An ENZYME produced by glandular tissue in the PROSTATE GLAND. When the gland enlarges (see PROSTATE, DISEASES OF), greater amounts of PSA are secreted, raising the concentration of the enzyme in the blood. This is especially so in cancer of the prostate, and testing the level of PSA is an indicator that the disease may be present. There is much controversy about the use of PSA as a screening test. Its proponents claim that its use reduces deaths from prostate cancer; its opponents suggest that it does this only by bringing to light many cases that needed no treatment and would not have caused death in any case. Further, if the level of PSA is very high, the disease is already advanced; where the result is equivocal it is uncertain whether the bene?ts of treatment outweigh the risks.... prostate specific antigen (psa)

Protoscolex

The scolex of a larval stage of the hydatid tapeworm. Morphologically it resembles the adult scolex.... protoscolex

Prova

(French) Woman of the province Provah, Provva, Provvah, Provia, Proviah, Provea, Proveah... prova

Provider

An individual health care professional, a group or an institution that delivers care services.... provider

Prudence

(English) One who is cautious and exercises good judgment Prudencia, Prudensa, Prudensia, Prudentia, Predencia, Predentia, Prue, Pru... prudence

Prunella

(Latin) Resembling a little plum Prunellah, Prunela, Prunellia, Prunelia, Prunelle, Prunele, Prunell, Prunel... prunella

Prussic Acid Poisoning

See CYANIDE POISONING.... prussic acid poisoning

Proteolytic

An enzyme or agent that speeds up the breaking down or digestive hydrolysis of proteins into smaller proteins, peptides, polypeptides, oligopeptides, amino acids, and all that delicious nitrogenous slurry-stuff.... proteolytic

Protima

(Hindi) One who dances Protimah, Proteema, Proteemah, Proteima, Proteimah, Protiema, Protiemah, Proteama, Proteamah, Protyma, Protymah... protima

Protocol

Standards or practices developed to assist health care providers and older persons to make and effect decisions about particular steps in the treatment process.... protocol

Prunus Amygdalus

Batsch var. amara (bitter); var. sativa (sweet).

Family: Rosaceae.

Habitat: Cultivated in Kashmir at elevation of 760-2,400 m, also in Himachal Pradesh and Uttar Pradesh.

English: Almond.

Ayurvedic: Vaataama, Vaataada.

Unani: Baadaam Shireen, Loz.

Siddha/Tamil: Vaadumai.

Action: Kernels—nutritious, demulcent and stimulant nervine tonic; valuable in diets for peptic ulcer. Unripe fruits— astringent, applied to gums. Oil—nutritive, demulcent, slightly laxative.

Almond flour made from the residue left after expressing almond oil, and almond butter, is used for the preparation of starch-free diabetic food.

The chief protein of almond is a globulin, amandin, an albumin is also reported. Amandin has a high arginine content (11.9%). The primary chemical difference between the sweet and bitter kernel lies in the high content (2.5-3.5%) of amygdalin in bitter kernel; the ripe sweet almond being free of this cyanogenetic glucoside. Owing to the presence of amygdalin, which on enzymatic hydrolysis yields hydrocyanic acid, the bitter almond is not fit for human consumption.

The oil yield from bitter kernels is usually 38 to 45% and from sweet almond 44 to 55%. The bitter almond oil containing hydrocyanic acid finds limited use in medicine as an antispas- modic and sedative. Dissolved in 50 times water, it is applied externally in prurigo senilis. Hydrocyanic acid-free oil is used for flavouring purposes.

Partial replacement of saturated fatty acids with almonds lowers total plasma cholesterol and low-density lipoprotein cholesterol.... prunus amygdalus

Prunus Armeniaca

Linn.

Family: Rosaceae.

Habitat: North-western Himalayas, particularly in the valleys of Kashmir, Chenab and Kullu, and in Simla hills at altitudes of 3,000 m.

English: Apricot.

Ayurvedic: Peetaalu, Aaluka, Urumaana.

Unani: Khuubaani, Mashmash.

Action: Powdered kernels— antitussive, antiasthmatic.

The dried apricot contains, 3,4- dihydroxybenzoic, chlorogenic and vanillic acids, quercetin, quercitrin, rutin, hyperoside and kaempferol. Apricot leaves contain quercetin, cy- nadin, kaempferol, caffeic acid and p-coumaric acid.... prunus armeniaca

Prunus Avium

Linn.

Family: Rosaceae.

Habitat: Native to Eurasia; cultivated in Kashmir, Kumaon and Himachal Pradesh.

English: Sweet Cherry.

Ayurvedic: Elavaaluka, Elaya, Harivaaluka.

Folk: Gilaas, Krusbal.

Action: Fruit stalks—diuretic, antiinflammatory, astringent, used for oedema, inflammation of urinary tract, cystitis, nephritis, urinary retention.

The stems contain salicylic acid, organic acids tannins and potassium salts. Protocatechuic, p-coumaric, fer- ulic and diferculic acids have been identified in the shoots.

The fruit contains salicylates and cyanogenic glycosides, and vitamin A, B1 and C. Sugars consist mainly of glucose and fructose, with sucrose as a minor component. Malic acid is the principal acid, small amounts of citric, tartaric and succinic acids are also reported. The lipids of the fruit pulp contain cis-vaccenic acid.

The acetone extract of peduncle gave an isoflavone, prunetin, which on hydrolysis yielded an aglycone identified as prunetin and sugar as glucose.

The seeds contain a cyanogenic gly- coside and are toxic. The bark contains tannins up to 16%.

Dosage: Seed—3-5 g powder. (CCRAS.)... prunus avium

Prunus Cerasoides

D. Don.

Synonym: P. puddum Roxb. ex Brandis. non-Miq.

Family: Rosaceae.

Habitat: The temperate Himalayas from Garhwal to Sikkim, also in Ootacamund.

English: Wild Himalayan Cherry, Bird Cheery.

Ayurvedic: Padmaka, Padma- gandhi, Padmaadyaa, Padmaakha, Padmakaashtha.

Action: Kernel—antilithic. Stem— refrigerant, antipyretic. Tender branches are crushed and soaked in water and taken internally to avert abortion. Oil—similar to that of bitter almond oil.

The plant contains a flavone glu- coside, puddumin-A. The root bark contains beta-sitosterol, stigmasterol, ursolic acid, prunetinoside, glucogen- kwanin and neosakuranin. Seeds contain flavonoid glycosides.

The leaves, twigs, bark and kernels contain a cyanogenetic substance.

Dosage: Heartwood—1-3 g powder. (API, Vol. III.)... prunus cerasoides

Pryce

(American / Welsh) One who is very dear / an enthusiastic child Price, Prise, Pryse... pryce

Pryor

(American) A wealthy woman; prosperous Pryar, Pryer, Pryier... pryor

Pseudohermaphrodite

A person in whom the gonads (testes or ovaries

– see GONAD) of only one sex are present in the body but in whom the external GENITALIA may not be obviously male or female. The condition is a result of a hormonal imbalance and can normally be treated by appropriate surgery and hormone drugs. (See also HERMAPHRODITE.)... pseudohermaphrodite

Prunus Cerasus

Linn.

Family: Rosaceae.

Habitat: Native of Eurasia; cultivated in Kashmir, Himachal Pradesh and Kumaon for edible fruits.

English: Sour Cherry.

Ayurvedic: Elavaaluka (var.).

Folk: Aalu-baalu, Gilaas.

Action: Fruit—diuretic, anti- inflammatory. Used for genitourinary inflammations, cystitis and urine retention. Bark—febrifuge, antidiarrhoeal. Fruit stalk—diuretic. Fruit stalk and stem—pectoral. Bark and fruit stalk—astringent. Kernel—nervine. Leaf—an infusion is given for convulsions in children.

Key application: Heartwood—in skin eruptions, erysipelas, obstinate skin diseases, haemorrhagic diseases. As a tonic for promoting conception. (The Ayurvedic Pharmacopoeia of India.)

The leaves, fruits and bark gave flavone glycosides. The bark contains 5-7% tannin. The kernel contains a considerable proportion of hydrocyanic acid. The leaves contain amyg- dalin. (Amygdalin, a nitrile glycoside, has been reported to inhibit the growth of Sarcoma-180 cells in culture.)... prunus cerasus

Prunus Domestica

Linn.

Synonym: P. communis Huds.

Family: Rosaceae.

Habitat: Cultivated in Kashmir, Himachal Pradesh and Kumaon.

English: Prune.

Ayurvedic: Aaruka (Prunus domestica var. insititia). Aaluubukhaaraa.

Unani: Aaluuchaa.

Siddha/Tamil: Alpagada-pungam.

Action: Fruit—refrigerant, laxative, nutritive. Improves haemoglobin levels in iron deficiency. Promotes excretion of excess calcium by the kidneys. An adjuvant for atherosclerosis and arthritis. Root—astringent.

The fruit pulp contains about 44% sugar and malic acid as major constituents. Kernel contains fixed oil about 45% and amygdalin and benzoic acid among others.

The crude extract of the fruit was found effective in controlling centrally induced emesis in dogs. The action was comparable to that of Metoclopramide (Maxolon) and chlorpro- mazine (Largactil).... prunus domestica

Prunus Mahaleb

Linn.

Family: Rosaceae.

Habitat: Native to Europe and West Asia, introduced in India and grown as an ornamental.

English: Mahaleb Cherry.

Ayurvedic: Gandha-priyangu. (Priyangu is equated with Callicarpa macrophylla Vahl.)

Unani: Mahlib, Habb-ul-Mihlab.

Folk: Ghaulaa (Maharashtra).

Action: Kernel—paste applied externally for treating freckles and blemishes. Contains coumarin, salicylic acid, amygdalin and hydrocyanic acid as major constituents; the oil gave alpha-elecsteric acid.... prunus mahaleb

Prunus Persica

Batsch.

Synonym: Persica vulgaris Nutt. Amydgala persica Linn.

Family: Rosaceae.

Habitat: Native to China; cultivated in Kashmir, Himachal Pradesh and Kumaon.

English: Peach.

Ayurvedic: Aaluka, Aaruka, Aru, Pichuka.

Action: Fruit—mild tranquillizer, expectorant, diuretic, antipyretic. Bark or leaves—used as tea for morning sickness, dry and hard cough, whooping cough and bronchitis. Leaves—used in leucoderma.

Flowers—galactagogue. Peach seeds are a constituent of a traditional Chinese herbal drug which has been used for the treatment of gynaecological disorders such as hypermen- orrhea, dysmenorrhoea and infertility.

Peach fruit extract containing nitrile glycosides, such as prunasin and amyg- dalin, has been reported to inhibit the growth of Sarcoma-180 cells in culture.

Fast-acting, wrinkle-eliminating cosmetic formulations contain peach kernel extract as one of the components.

The heartwood contains beta-sitos- terol and its D-glucoside, hentriacon- tane, hentriacontanol, and the flavo- noids naringenin, dihydrokaempferol, kaempferol and quercetin.... prunus persica

Pseudohypertrophic Muscular Dystrophy

A condition in which certain muscles enlarge owing to a fatty and ?brous degeneration, giving a false appearance of increased strength.

Pseudomonas Aeruginosa

A pathogenic bacterium of the genus pseudomonas – rod-like, motile gram-negative bacteria (see GRAM’S STAIN) – that occurs in pus from wounds and is associated with urinary tract infections. The bacteria mostly live in soil and decomposing organic matter and help to recycle nitrogen in nature. Most of the bacteria in this genus are harmless to humans.... pseudohypertrophic muscular dystrophy

Pseudarthria Viscida

Wt. & Arn.

Family: Papilionaceae; Fabaceae.

Habitat: Orissa throughout South India and Gujarat.

Ayurvedic: Sanaparni, Shaalaparni (Kerala).

Siddha/Tamil: Neermalli.

Action: Root—astringent, febrifuge, antirheumatic. A decoction or powder is used for biliousness and diarrhoea. Used as a substitute for Desmodium gangeticum (Shaalaparni) in South India.

Leucopelargonidin has been isolated from the root.... pseudarthria viscida

Psidium Guajava

Linn.

Family: Myrtaceae.

Habitat: Native to Central America; cultivated chiefly in Uttar Pradesh, Punjab, Bihar, Maharashtra, and Andhra Pradesh.

English: Guava

Ayurvedic: Peruka (non-classical), Amaruuda.

Siddha/Tamil: Koyya.

Action: Unripe fruit—antidiar- rhoeal. Leaves—used for dysentery, diabetes, cough and cold. Flowers— anthelmintic.

Guava juice may be helpful in regulating blood sugar in type 2 diabetes and syndrome X. (Sharon M. Herr.)

A residue obtained from methanolic fraction of unripe fruits was found to possess significant antidiarrhoeal activity. The fraction decreased gastric motility in an experimental animal model. The fraction was also found to inhibit significantly the growth of different strains of Shigella sp. and Vibrio cholerae.

In China and Taiwan, the leaf extract is administered for treating diarrhoea, dysentery, diabetes and inflammations. The leaf extract (containing quercetin) inhibits acetylcholine release in the gastro-intestinal tract which might account for us antidiarrhoeal activity. An extract of leaves with a little salt is given in relieve whooping cough.

In New Papua Guinea, decoction of new leaf tips is drunk to treat hepatitis.

Guava seed oil contains very higher proporation of linoleic acid (75.52%) than sunflower, groundnut, olive, soybean and coconut oil. The seeds from Pakistan yield 9.25% of a fatty oil.

Vitamin C content of the ripe fruit ranges from 100 to 1000 mg/100 g. It is highest in the skin and in the flesh next to it.

Psidium cattleyanum Sabine is equated with Straberry Guava and is known as Seemai Koyya in Tamil Nadu and Pahari Payaar in Bengal. The fruit contains vitamin C 15-44 mg/100 g.

Smaller var. of Guava is equated with Psidium guineense Sw. It is found in Tripura.... psidium guajava

Psoralea Corylifolia

Linn.

Family: Papilionaceae; Fabaceae.

English: Babchi, Purple Fleabane.

Habitat: Rajasthan., eastern districts of Punjab and adjoining areas of Uttar Pradesh.

Ayurvedic: Somaraaji, Somavalli, Somavallik, Soma, Chaandri, Vaakuchi, Baakuchi, Avalguja. (Somaraaji and Avalguja have also been equated with Centratherum anthelminticum.)

Unani: Baabchi, Bakuchi.

Siddha/Tamil: Karpoogaarisi.

Action: Seed—used in leucoderma, vitiligo, leprosy, psoriasis and inflammatory diseases of the skin, both orally and externally. (The Ayurvedic Pharmacopoeia of India.)

The seed and roots contain chal- cones, flavones, isoflavones, furano- coumarins and coumesterol group of compounds. These include psoralen, isopsoralen, bavachinin.

A mixture of psoralen and isopso- ralen, in a ratio of 1:3, is recommended for topical application in leucoderma. These furanocoumarins initiate transformation of DOPA to melanin under the influence of UV light. Seeds are powdered and administered orally with warm water (5 g/day) in cases of eczema.

Psoralen was found to be cytotoxic in vitro. The combination therapy of psoralen and UV irradiation has been shown to inhibit the growth of tumours in vivo.

Bavachinin-A, isolated from the fruits, exhibited marked anti-inflammatory, antipyretic and mild analgesic properties similar to those of oxyphenylbutazone and hydrocortisone. It demonstrated better antipyretic activity than paracetamol experimentally.

Oral administration of the powdered seeds has generally resulted in side reactions (nausea, vomiting, purging); external application generally proved highly irritant to the skin.

Dosage: Seed—1-3 g powder (CCRAS.); 3-6 g powder (API, Vol. I).... psoralea corylifolia

Psoralens

See PHOTOCHEMOTHERAPY; PHOTODERMATOSES.... psoralens

Psoriasis Plantaris

Psoriasis of the sole... psoriasis plantaris

Psychedelic Drugs

Drugs, such as CANNABIS and LYSERGIC ACID DIETHYLAMIDE (LSD), that expand consciousness and perception. (See DEPENDENCE.)... psychedelic drugs

Psychogeriatric Facility

Institutions which provide a domestic setting for confused, older people who require 24-hour care, but whose behaviour makes them unsuitable for accommodation in a general purpose facility.... psychogeriatric facility

Psychological And Social Problems

Any previously existing mental-health problems may worsen under the stress of pregnancy and childbirth, and a woman’s socio-economic circumstances may be an in?uential factor. Mood swings are common in pregnant women and mothers of new babies; sympathetic support from sta? and relations will usually remedy the situation. If postnatal depression lasts for more than a week or two the use of mild ANTIDEPRESSANT DRUGS may be justi?ed. If depression persists, referral to a psychiatrist may be advisable. Rarely, severe psychiatric problems – puerperal psychosis – may develop during or after pregnancy and referral to an appropriate psychiatric unit is then essential. If the mother’s social circumstances are unsatisfactory, advice should be sought from social services departments. Mothers may also need advice on bene?ts to which they are entitled and how to claim them. Bene?ts Agency o?ces or Citizens’ Advice Bureaux as well as antenatal clinics are useful sources of information.... psychological and social problems

Psychopathic

Psychopathic disorder is de?ned by the Mental Health Act 1983 as a persistent disorder or disability of mind (whether or not including signi?cant impairment of intelligence) which results in abnormally aggressive or seriously irresponsible conduct. The cardinal features are as follows: (1) Absence of normal feelings for other people such as love, affection, sympathy and condolence. (2) A tendency to antisocial impulsive acts with no forethought of the consequences. (3) A failure to learn by experience and to be deterred from crime by punishment.

(4) Absence of any other form of mental disorder that would explain the unusual behaviour. The corresponding American terminology is ‘antisocial personality disorder’. (See MENTAL ILLNESS.)... psychopathic

Psychosexual

Relating to the relationships between the behavioural, emotional, mental and physiological characteristics of sex or sexual development.... psychosexual

Psychotic

Adjective describing PSYCHOSIS or noun referring to someone with a psychosis.... psychotic

Pthiriasis

Infestation with the crab (or pubic) louse, Pthirus pubis.... pthiriasis

Psychosomatic Diseases

Taken at face value, the term ‘psychosomatic’ simply means the interaction of psyche (mind) and soma (body). As such it is a noncontroversial concept that points out the many ways in which psychological factors affect the expression of physical disorder and vice-versa. Few doubt that stress makes many physical illnesses worse, at least as far as symptoms are concerned. There are also few physical illnesses in which the outcome is not made worse by psychological factors: depression after a heart attack, for example, has a worse e?ect on prognosis than even smoking. A little more problematic is the very popular belief that stress causes relapses of physical disorders, such as cancer; some studies have found this to be the case, others not.

However, calling a condition psychosomatic implies something more – the primacy of the psyche over the soma. Going back to the in?uential theories and practice of PSYCHOANALYSIS as expounded from the 1930s, many diseases have been proposed as the result of psychological factors.These have included PEPTIC ULCER, ULCERATIVE COLITIS, ASTHMA, PSORIASIS and others. In this view, much physical disorder is due to repressed or excessive emotions. Likewise it is also argued that whereas some people express psychological distress via psychological symptoms (such as anxiety, depression and so on), others develop physical symptoms instead – and that they are also at greater risk of physical disease.

The trouble with this view is that medical advances repeatedly show that it goes too far. Stress certainly causes physical symptoms – for example, DYSPEPSIA – but the belief that it caused peptic ulcers vanished with the discovery of the true cause: colonisation of the stomach by the bacterium, Helicobacter pylori. Of course, stress and social adversity affect the risk of many diseases. For example, the incidence of heart disease among UK government employees (civil servants) has been shown to be in?uenced by their social class and their degree of job satisfaction. But we do not know how this works. Some argue that social adversity and stress in?uence how the heart functions (‘He died of a broken heart’). Stress can also affect IMMUNITY but it cannot cause AIDS/HIV and we do not know if there is a link running from stress to abnormal immune function to actual illness.

We can say that psychological factors provoke physical symptoms, and often even explain how this can happen. For example, when you are anxious you produce more epinephrine (adrenaline), which gives rise to chest pain, ‘butter?ies in the stomach’ and PALPITATION. These symptoms are not ‘all in the mind’, even if the trigger is a psychological one. People who are depressed are more likely to experience nearly every physical symptom there is, but especially pain and fatigue. Taken as a whole, psychologically induced symptoms are an enormous burden on the NHS and probably responsible for more doctor visits and sickness absence than any other single cause. Also we can be con?dent that social adversity and stress powerfully in?uence the outcome of many illnesses; likewise, a vast range of unhealthy activities and behaviours such as smoking, excessive alcohol intake, excessive eating, and so on. But we must be careful not to assume that our emotions directly cause our illnesses.... psychosomatic diseases

Public Good

A good or service whose benefits may be provided to a group at no more cost than that required to provide for one person. The benefits of the good are indivisible and individuals cannot be excluded. For example, a public health measure that eradicates smallpox protects all, not just those paying for the vaccination.... public good

Public Sector

See “statutory sector”.... public sector

Publication Bias

Unrepresentative publication of research reports that is not due to the quality of the research but to other characteristics, e.g. tendencies of investigators to submit, and publishers to accept, positive research reports (i.e. ones with results showing a beneficial treatment effect of a new intervention).... publication bias

Puck

(English) A mischievous fairy... puck

Psyllium

Plantago ovata or P. ispaghula, P. psyllium.

N.O. Plantagineae.

Synonym: Flea Seed, Fleawort.

Features ? Over one hundred species of this genus of stemless, herbaceous plants are known to botanists. The seeds of two of these are used in herbal medicine.

Plantago ispaghula, or Light Indian Psyllium, is cultivated in India. Seeds are boat- shaped, with one end sharper than the other, and grey-brown in colour, A small brown spot is a feature of the convex side. Transparent mucilage surrounds the seeds when kept in water.

Plantago psyllium, which yields the so-called Dark Brilliant Indian Psyllium seeds, is indigenous to many parts of Southern Europe and Northern Africa, and is largely cultivated in France and Spain. These seeds are the most highly esteemed for therapeutic purposes, although they do not contain so much mucilage as the Ispaghula. The "English Golden" variety is even less mucilaginous, and is used mainly for feeding birds.

Psyllium seeds are tasteless and odourless, and their peculiar action on the intestines renders them of particular value in sluggishness and atony of this organ. Swelling into a demulcent, jelly-like mass, which gently lubricates and stimulates the bowels, the seeds do not gripe, and their action is certain. Probably nothing better than Psyllium seeds can be given to most people for constipation, and they are eminently suited to children. The adult dose varies between two and four teaspoonfuls after meals, children proportionately with their age.

In tropical countries the seeds are helpful in the treatment of dysentery.... psyllium

Pterocarpus Dalbergioides

Roxb.

Family: Fabaceae.

Habitat: The Andamans, sparingly cultivated in West Bengal.

English: Andaman Padauk, Andaman Redwood.

Ayurvedic: Rakta-chandana (var.).

Siddha: Vengai (Tamil), Yerravegisa (Telugu).

Folk: Chalangada (Andamans).

Action: See Pterocarpus santalinus.

The wood contains a red pigment santalin and a yellow flavonoid santal, both of which also occur in Pterocarpus santalinus. The bark and the heartwood contain pterostilbene. The heartwood yields pterocarpin, liquirit- igenin and isoliquiritigenin. The sapwood gave homopterocarpin additionally.

Pterocarpus indicus Willd. non-Baker, Malay Padauk, is also known as Vengai in Tamil and Yerravegisa in Telugu. A decoction of the wood is given in dropsy and for stone in the bladder. The bark-kino is used as an application for sores and a decoction of the bark or kino is used for diarrhoea.... pterocarpus dalbergioides

Pterocarpus Marsupium

Roxb.

Family: Papilionaceae; Fabaceae.

Habitat: Throughout the tropical zones of India in the hilly regions.

English: Indian Kino tree, Malabar Kino tree.

Ayurvedic: Asana, Bijaka, Priyaka, Pitashaala.

Unani: Bijaysaar.

Siddha/Tamil: Vengai.

Action: Bark-kino—astringent, antihaemorrhagic, antidiarrhoeal. Flowers—febrifuge. Leaves—used externally for skin diseases.

Key application: Heartwood— in anaemia, worm infestation, skin diseases, urinary disorders, lipid disorders and obesity. Stem bark—in diabetes. (The Ayurvedic Pharmacopoeia of India.)

The heartwood and roots contain isoflavonoids, terpenoids and tannins. Tannins include the hypoglycaemic principle (-)-epicatechin. Stilbenes, such as pterostilbene; flavonoids, including liquiritigenin, isoliquiritige- nin, 7-hydroxyflavanone, 7,4-dihy- droxyflavanone, 5-deoxykaempferol and pterosupin; a benzofuranone mar- supsin and propterol, p-hydroxy-ben- zaldehyde are active principles of therapeutic importance.

The gum-kino from the bark provides a non-glucosidal tannin, Kino tannic acid (25-80%).

The (-)-epi-catechin increases the cAMP content of the islets which is associated with the increased insulin release, conversion of proinsulin to insulin and cathepsin B activity.

Oral administration of ethylacetate extract of the heartwood and its fla- vonoid constituents, marsupin, ptero- supin and liquiritigenin, for 14 consecutive days to rats exhibited a significant reduction of serum triglycerides, total cholesterol and LDL- and VLDL-cholesterol levels, but it did not exert any significant effect on HDL- cholesterol.

The ethanolic and methanolic extracts of the heartwood exhibited significant in vitro antimicrobial activity against Gram-positive and Gramnegative bacteria and some strains of fungi.

Kino is powerfully astringent. The therapeutic value of kino is due to Kino tannic acid.

Dosage: Heartwood—50-100 g for decoction. (API, Vol. I); stem bark—32-50 g for decoction (API, Vol. III).... pterocarpus marsupium

Puerperal Depression

Also called postnatal DEPRESSION, this is the state of depression that may affect women soon after they have given birth. The condition often occurs suddenly a day or so after the birth. Many women suffer from it and usually they can be managed with sympathetic support. If, however, the depression – sometimes called ‘maternal blues’ – persists for ten days or more, mild ANTIDEPRESSANT DRUGS are usually e?ective. If not, psychiatric advice is recommended. (See PREGNANCY AND LABOUR.)... puerperal depression

Puja

(Hindi) In Hinduism, a religious ritual Pujah, Pooja, Pouja... puja

Pulcheria

(Italian) A chubby baby Pulcheriah, Pulcherea, Pulchereah, Pulcherya, Pulcheryah, Pulcheriya, Pulcheriyah... pulcheria

Pules

(Native American) Resembling a pigeon... pules

Pulicaria Dysenterica

Bernh.

Family: Asteraceae.

Habitat: Kashmir at 1,500-1,800 m.

Action: Plant—astringent, diuretic. Root—antidiarrhoeal. Leaf— antiasthmatic.... pulicaria dysenterica

Pterocarpus Santalinus

Linn. f.

Family: Papilionaceae; Fabaceae.

Habitat: Found in Cuddaph district of Andhra Pradesh, neighbouring areas of Tamil Nadu and Karnataka.

English: Red Sandalwood, Red Sanders.

Ayurvedic: Raktachandana, Raktasaara.

Unani: Sandal Surkh.

Siddha/Tamil: Shivappu chandanam.

Folk: Laal-chandan.

Action: Heartwood—antibilious, anti-inflammatory, hypoglycaemic, astringent, diaphoretic, febrifuge.

A paste of wood is used externally for inflammations and headache. Fruit—antidysenteric

The heartwood contains terpeno- ids—eudesmol, iso-pterocarpolone, pterocarpol, cryptomeridiol, ptero- carptriol and pterocarpdiolone; pigments santalins A and B. The bark contains triterp enoids—b eta- ampyrone, lupenone and lupeol derivatives. The sapwood gave acetyl oleanolic aldehyde, acetyl oleanolic acid and ery- throdiol.

An ethanolic extract (95%) of the wood powder was found effective in lowering blood sugar levels in fasting, fed, glucose-loaded and streptozotocin diabetic models in rats.

A cream prepared from the metha- nolic extract of the heartwood of Red Sandalwood and rhizomes of Curcuma longa showed 95.46% inhibition of oedema in combination (Curcuma lon- ga and red sandalwood showed 65.62 and 64.14% inhibition respectively, when used individually).

A decoction of the heartwood produced potentiation of pentobarbitone- induced hypnosis in albino mice; blocked conditioned avoidance response in rats and showed anticonvul- sant and anti-inflammatory activities.

Dosage: Heartwood—3-6 g powder. (API, Vol. III.)... pterocarpus santalinus

Pterospermum Acerifolium

Willd.

Family: Sterculiaceae.

Habitat: Maharashtra, Manipur, North Bengal, Bihar and Assam, Western Ghats and Andaman Islands.

English: Hathipaila.

Ayurvedic: Muchukun- da, Muchakunda, Kshatra- vriksha, Chivuka, Prativishnuka, Muchukunda Champaa. Karnikaara (also equated with Cassia fistula).

Unani: Gul-e-Muchkun.

Siddha/Tamil: Vennangu.

Action: Flower—anti-inflammatory, styptic (used for bleeding piles, haematuria, ulcers). Charred flowers and bark, mixed with the powder of Mallotus philippinensis, are applied to smallpox eruptions.

The fresh flowers yielded kaempfe- rol- 3 - O -beta - D -galactoside, along with luteolin and its 7-O-glucoside. The leaves also contain betulin, lu- peol, bauerenol, friedelin and beta- sitosterol.

Dosage: Flower—3-6 g powder. (CCRAS.)... pterospermum acerifolium

Pterospermum Canescens

Roxb.

Synonym: P suberifolium Lam. non-Roxb.

Family: Sterculiaceae.

Habitat: Karnataka and Tamil Nadu, occasionally planted in West Bengal.

Ayurvedic: Muchukunda (var.)

Siddha/Tamil: Sempulavu.

Action: Flowers—anodyne; a paste with rice-water and vinegar is used externally in migraine. Leaves— applied externally in headache.

Flowers gave arachidic, linoleic, my- ristic, oleic, palmitic and stearic acids and beta-sitosterol, kaempferol-3- beta-D-galactoside and kaempferol- 3-rutinoside. The flavonoids present in the leaves are kaempferol-3-beta-D- galactoside, kaempferol, quercetin and its 3-O-arabinoside and 3-O-rhamno- side. The leaves also contain betulin, beta-amyrin, lupeol, bauerenol, friede- lin, taraxerone and beta-sitosterol.... pterospermum canescens

Pulika

(African) An obedient and well- behaved girl

Pulikah, Pulicca, Pulicka, Pulyka, Puleeka, Puleaka... pulika

Pulmonary Diseases

See LUNGS, DISEASES OF.... pulmonary diseases

Pu’erh Tea Pros And Cons

Pu’erh tea is a type of post-fermented tea produced in China. Read this article to find out more about its many health benefits! About Pu’erh Tea Pu’erh tea is a post-fermented tea produced in the Chinese province Yunnan. Post-fermented teas are different from other types of tea in the sense that, after the leaves are dried and rolled, they undergo a microbial fermentation process. The pu’erh teais available as loose leaves or as tea brick (tea leaves packed in molds and pressed into block form). There are also two categories of pu’erh tea: the raw type and the ripe type. Raw pu’erh tea can count as a type of green tea. Ripened or aged pu’erh tea is often mistakenly called a type of black tea, though it isn’t. How to prepare Pu’erh Tea Pu’erh tea can be bought and prepared in loose leaf form, in tea bag form, or in compacted cake form. If you’re using leaves, add a teaspoon to a cup of freshly boiled water and let it steep for about 20 seconds before you pour off the water; this process id called rinsing, in order to prepare the leaves for the tea. Next, pour freshly boiled water again, let it steep for 30 seconds or one minute. This will give the tea a mild, but pleasant flavor. If you want a stronger flavor, you can let it steep up to 50 minutes, until it turns as dark as coffee. Pu’erh leaves can be resteeped several times (4-8 times). Just add about 20 more seconds to each steeping process. The same applies to pu’erh tea in compacted cake form. To get the leaves, either flake off pieces of the cake, or steam the entire cake until it becomes soft. Pu’erh Tea Benefits Pu’erh tea had important health benefits related to blood circulation. It can help lower blood cholesterol levels. It also boosts the flow of blood and enhances your blood circulation. Drinking pu’erh tea can help prevent cancer, as it helps prevent the formation and growth of cancer cells. It also promotes a proper, healthy digestion, and is good for your spleen. You don’t have to worry even if you’re on a diet; drinking pu’erh tea will help you lose weight, as it breaks down and reduces the fat in your body. As pu’erh tea contains caffeine, drinking it helps keep you alert and focused. It also helps with removing toxins from your body, and it can prove to be useful if you’re dealing with various aches and pains. Pu’erh tea can also help you if you’ve got a hangover, especially if you get a headache. Also, it can act as a substitute for coffee, and can have a relaxing effect on you. Pu’erh Tea Side Effects Because of its caffeine content, pu’erh tea shouldn’t be consumed by pregnant or breastfeeding women, as it can affect the baby. Also, you shouldn’t drink pu’erh tea if you’ve got anxiety, bleeding disorders, heart problems, diabetes, irritable bowel syndrome, glaucoma, high blood pressure or osteoporosis. It can affect your condition in all of these cases. Pu’erh tea can also interact with medications. A few examples include amphetamines, cimetidine, ephedrine, adenosine, or medications for depression, asthma and slow blood clotting. The list includes more, so if you’re under medication, make sure you check with your doctor first, to see if it’s safe to drink pu’erh tea.   Pu’erh tea has important health benefits, though the same goes for side effects, as well. Make sure it’s safe to drink pu’erh tea, and then you can enjoy a cup of tea without having to worry about its side effects.... pu’erh tea pros and cons

Public Health Laboratoryservice (phls)

A statutory organisation that is part of the NHS. It comprises ten laboratory groups and two centres in the UK, with central coordination from PHLS headquarters. The service provides diagnostic-testing facilities for cases of suspected infectious disease. The remit of the PHLS (which was set up during World War II and then absorbed into the NHS) is now based on legislation approved in 1977 and 1979. Its overall purpose was to protect the population from infection by maintaining a national capability of high quality for the detection, diagnosis, surveillance, protection and control of infections and communicable diseases. It provided microbiology services to hospitals, family doctors and local authorities as well as providing national reference facilities. In 2001 it was incorporated into the newly established NATIONAL INFECTION CONTROL AND HEALTH PROTECTION AGENCY.... public health laboratoryservice (phls)

Pueraria Lobata

(Willd.) Ohwi.

Family: Papilionaceae; Fabaceae.

Habitat: Eastern Himalayas, Assam and Khasi Hills.

English: Tropical Kudze.

Ayurvedic: Vidaari (var.).

Action: Root—antipyretic, antiinflammatory, spasmolytic. Flower—hepatoprotective.

The root of P. lobata is used in Chinese medicine as an antipyretic and spasmolytic agent.

The root contains pueraria glyco- sides and puerarol. The glycosides showed strong antioxidant activity and inhibited lipid peroxidation. The root also contain several flavones which showed 66.8% inhibition against stomach cancer in vivo in mice. The isofla- yvonoids, daidzein, formononetin, daidzin and puerarin. Daidzein and puerarin show significant anti-inflammatory activity.

The cosmetics containing the root extracts with 20-40% puerarin and 2045% sugars (as sucrose) are used as moisturizing, skin-lightening and sun- screening and hair-growth stimulating preparations.

An isoflavonoid, triterpenoid sapo- nin and tryptophan derivative isolated from the flowers showed protective effect against experimental liver injuries in mice.

The tryptophan derivatives and their glycosides exhibited antihyperglycae- mic activity.

Pueraria phaseoloides (Roxb.) Benth., synonym P. javanica Benth. (Sub-Himalayan regions; Assam, An- dhra Pradesh, Tamil Nadu and Kerala, up to 1,100 m) is equated with Tropical Kudze. The plant is used against ulcers and boils.... pueraria lobata

Pueraria Tuberosa

DC.

Family: Papilionaceae; Fabaceae.

Habitat: Punjab, Western Uttar Pradesh, Central India.

English: Indian Kudze.

Ayurvedic: Vidaari, Swaadukandaa, Ikshugandhaa, Gajavaajipriyaa, Kandapalaasha, Bhuumikushmaan- da. (Substitute for Jivaka and Rshabhaka.)

Folk: Bhui-kumhadaa, Suraal.

Action: Tuber—diuretic, cardiac tonic, galactagogue. Also used for fertility control. Root—used as a demulcent, and refrigerant in fevers, as cataplasm for swelling of joints, as galactagogue.

The butanolic extract of Pueraria tuberosa showed significant protection against hepatic damage in rats. The ethanolic extract of the tubers and its butanol and pre-puerarin fractions exhibited anti-implantation effect. The pure compounds, puerarin, daidzein and tuberosin, exhibited significant anti-implantation activity in hamsters.

In Indian medicine, Vidaari and Kshira-vidaari are used for promoting breast milk and semen, and as a restorative tonic. Most authors have equated Vidaari with Pueraria tuberosa and Kshira-vidaari with Ipomoea digi- tata.

In Western herbal, Pueraria lobata and P. tuberosa roots are used alone or in combination with other products for symptoms due to alcoholism. But preliminary research shows that Kudze does not improve sobriety in chronic alcoholics. (Natural Medicines Comprehensive Database, 2007.)

Dosage: Tuber—3-5 g powder. (CCRAS.)... pueraria tuberosa

Pulmonary Surfactant

Naturally produced in the LUNGS by cells called pneumocytes, this substance is a mixture of phospholipids (see PHOSPHOLIPID) and LIPOPROTEINS. Present in ?uid lining the alveoli (see ALVEOLUS) in the lungs, their action helps maintain their patency. Premature babies may have a de?ciency of surfactant, a disorder which causes severe breathing diffculties – RESPIRATORY DISTRESS SYNDROME or hyaline membrane disease – and HYPOXIA. They will need urgent respiratory support, which includes oxygen and the administration (via an endotracheal tube) of a specially prepared surfactant such as beractant (bovine lung extract) or edfosceril palmitate.... pulmonary surfactant

Pulsatilla

Anemone pulsatilla. N.O. Ranunculaceae.

Synonym: Easter Flower, Meadow Anemone, Pasque Flower, Passe Flower, Wind

Flower.

Habitat: High pastures.

Features ? Stalk up to six inches high. Leaves hairy, three to five inches long by two to three inches broad, bi-pinnate, leaflets opposite, stalked below. Flowers (April and May) large, single, six dull violet petals. Taste pungent when fresh.

Part used ? Herb.

Action: Nervine, antispasmodic, alterative.

Nervous exhaustion in women, particularly when resulting from menstrual causes. Has a stimulating action on all mucous surfaces. Dose, 1-2 tablespoonfuls of the 1/2 ounce to 1 pint infusion.... pulsatilla

Pulsation

Also known as throbbing. An appearance seen or felt naturally below the fourth and ?fth ribs on the left side, where the heart lies, and also at every point where an artery lies close beneath the surface. In other situations, it may be a sign of ANEURYSM. In thin people, pulsation can often be seen and felt in the upper part of the abdomen, due to the throbbing of the normal abdominal AORTA.... pulsation

Pulse Oximetry

Measurement of OXYGEN saturation of HAEMOGLOBIN in a blood sample using a noninvasive device called a spectrophotometer.... pulse oximetry

Puma

(Latin) Resembling the mountain lion Pumah, Pumma, Pooma, Poomah, Pouma... puma

Pumpkin

See Calabaza.... pumpkin

Punctate Basophilia

See BASOPHILIA.... punctate basophilia

Punica Granatum

Linn.

Family: Punicaceae.

Habitat: Native to Iran; but cultivated throughout India.

English: Pomegranate.

Ayurvedic: Daadima, Daadim- ba, Raktapushpa, Dantabijaa, Raktakusumaa, Lohitpushpaka.

Unani: Anaar, Roomaan, Gulnaar, Gulnaar Farsi.

Siddha/Tamil: Maathulai.

Action: Rind of fruit—astringent, stomachic, digestive. Used for diarrhoea, dysentery, colitis, dyspepsia and uterine disorders. Leaf—used in stomatitis (recommended by The Ayurvedic Pharmacopoeia of India). Fresh juice of fruit—refrigerant, cosive, antiemetic; given as an adjuvant in diarrhoea, dyspepsia, biliousness, inflammations of the stomach, palpitation, excessive thirst and fevers. Bark of stem and root—anthelmintic, febrifuge. Given for night sweats. Rind of fruit, bark of stem and root— antidiarrhoeal. Powdered flower buds—used in bronchitis.

The fruit rind (dried) contains up to 26, stem bark 10-25, root bark 28 and leaves 11% tannin.

The rind gave an ellagitannin (granatin B, leaves gave granatins A and B and punicafolin); punicalagin, puni- calin and ellagic acid. Pentose gly- cosides of malvidin and pentunidin have also been isolated from the rind. Rind extract showed significant hypo- glycaemic activity in mildly diabetic rats.

Seeds gave malvidin pentose glyco- side.

Flowers gave pelargonidin-3,5-di- glucoside; also sitosterol, ursolic acid, maslinic acid, asiatic acid, sitosterol- beta-D-glucoside and gallic acid.

Extracts of the whole fruit were highly active against Micrococcus pyo- genes var. aureus, E. coli and Pseudomonas aeruginosa; also very effective against intestinal pathogenic bacilli.

Aqueous extract of the root was found to inhibit the activity of My- cobacterium tuberculosis 607.

The proanthocyanidins of pomegranate showed hypolipidaemic activity by their ability to enhance resistance of vascular wall preventing penetration of cholesterol into atherogenic lipopro- teins.... punica granatum

Pupa

The third stage in mosquito and other endopterygote insect development, emerging when the last larval instar shed its skin. Pupae swim but do not feed.... pupa

Purgatives

See LAXATIVES.... purgatives

Purified Protein Derivative (ppd)

Reagent used by intradermal administration in the Mantoux (tuberculin) test for TB.... purified protein derivative (ppd)

Purines

These are waste products or metabolites of nucleoproteins. They are not recyclable and are broken down further to the primary excretable form, uric acid. High purine presence in a tissue signifies a recent high turnover in nucleoproteins from injury or cell death, which is why some purines, such as allantoin, will stimulate cell regeneration. Many plants contain allantoin, most noticeably Comfrey. Some foods are heavy purine producers and can elevate serum uric acid levels. These include organ meats, seafood, legumes, and such politically correct foods as spirulina, chlorella, and bee pollen. Caffeine and theobromine are purine-based alkaloids and can mildly increase uric acid, but they pale beside algae, pollen, and glandular extracts from the chiropractor.... purines

Purity

(English) One who is chaste; clean Puritey, Puritee, Puriti, Puritie, Pura, Pureza, Purisima, Pure, Puritea... purity

Purnima

(Hindi) Born beneath the full moon Purnyma, Purnema, Purneima, Purniema, Purneema, Purneama... purnima

Purple Loose-strife

Lythrum salicaria. N.O. Lythraceae.

Synonym: Purple Grass, Willow Strife.

Habitat: By waterways; luxuriantly on river islands and banks.

Features ? Stem four- (sometimes six-) sided, up to four feet high. Leaves in pairs, threes or fours, nearly sessile, lanceolate, margins entire, two to five inches long. Flowers (July to September) large, reddish-purple, six to eight in rings round the stalk. Root woody.

Part used ? Herb.

Action: Febrifuge, astringent, alterative.

Chiefly in feverish conditions with other herbs. Sometimes as an astringent in diarrhea. Used alone, simmer 1 ounce in 1 1/2 pints water for ten minutes. Dose, wineglassful as required.... purple loose-strife

Putrid Fever

An old name for typhus fever (see ENTERIC FEVER).... putrid fever

Pyera

(Italian) Formidable woman Pyerah, Pyerra, Pyerrah, Pyira, Pyirra, Pyirah, Pyirrah... pyera

Pyllyon

(English) An enthusiastic woman Pylyon... pyllyon

Putranjiva Roxburghii

Wall.

Synonym: Drypetes roxburghii (Wall.) Hurusawa.Family: Euphoriaceae.

Habitat: Throughout tropical India, wild and cultivated as an avenue tree.English: Child-life tree, Indian Amulet Plant, Spurious Wild Olive.Ayurvedic: Putranjiva, Putrajivaka, Putrajiva, Yashtipushpa, Arth- saadhanaSiddha/Tamil: Karupali Garbhadaa and Garbhakaraa are misleading synonyms.Folk: Jiyaapotaa.

Action: Fruit—powered (deseeded) fruits are used against cough, cold and sprue. Rosaries of hard stones are used for protecting children from infections. (Due to misleading nomenclature, the "conception-promoting" property has been attributed to the drug in folk medicine. Its use is possible in vaginal infections and genitourinary diseases, or skin eruptions during pre-conception stage.)The seed kernel on steam distillation yield 0.5% of a sharp-smelling essential oil of the mustard oil type. The oil contains isopropyl and 2-butyl isothio- cyanates as the main constituents and 2-methyl-butyl isothiocyanate as a minor component. The iso-thiocyanates are produced on enzymic hydrolysis of glycosidic progenitors present in the kernels, viz. glucoputranjivin, gluco- cochlearin and glucojiaputin respectively. An additional glucoside, gluco- cleomin has been identified in the seed kernel, it affords a non-volatile mustard oil, cleomin. A glycosidic pattern similar to that in the seed is reported in the shoots and roots.The fruit pulp contains a large proportion of mannitol and small quantities of saponin glucosides and alkaloids.The seed coat gave putranjivoside, putranoside A, B, C and D, beta- sitosterol and tis beta-D-glucoside.The leaves gave amentoflavone and its derivatives, beta-amyrin and its palmite, polyphenols, putranjiva sa- ponin A,B,C, and D and stigmasterol.The bark contains friedelin, friede- lanol, friedelanone, friedelan-3,7-di- one (putranjivadione), 3-alpha-hydro- xy friedelan- 7-one (roxburgholone), carboxylic acid, putric acid, putran- jivic acid.The essential oil from leaves showed mild antifungal activity against Rhizoctonia solani.

... putranjiva roxburghii

Pygmaeopemna Herbacea

(Roxb.) Mold.

Synonym: Premna herbacea Roxb.

Family: Verbenaceae.

Habitat: Andhra Pradesh, Tamil Nadu and Orissa and in some parts of Kerala.

Ayurvedic: Bhumi-jambu.

Siddha/Tamil: Siru Thekku.

Action: Rootstock—antiasthmatic. Leaf— bechic, febrifuge. Rootstock and leaf—antirheumatic. (Sold in South Indian market as Bhaarangi.)

A diterpenoid quinonemethide (bharangin) is reported from the plant.... pygmaeopemna herbacea

Pyogenic Membrane

The membrane that lines and isolates abcesses.... pyogenic membrane

Pyorrhea

Broadly, any discharge of pus, but usually referring to periodontitis or Pyorrhea alveolaris, with inflammatory and degenerative conditions in the gums, jaw bone and cementum. There may be alveolar bone resorption, teeth loss and receding gums...and hefty dental and oral surgery bills. These costs may be valid, but there is some thought in some radical dental circles that there is overdiagnosis of the condition.... pyorrhea

Pyrena

(Greek) A fiery woman Pyrenah, Pyrina, Pyrinah, Pyryna, Pyrynah, Pyreena, Pyreenah, Pyriena, Pyrienah, Pyreina, Pyreinah, Pyreana, Pyreanah... pyrena

Pyria

(American) One who is cherished Pyriah, Pyrea, Pyreah, Pyriya, Pyriyah, Pyra, Pyrah... pyria

Pyrogenic

Fever causing... pyrogenic

Pyrola Rotundifolia

Linn.

Family: Pyrolaceae.

Habitat: North-Western and eastern Himalaya at altitudes of 2,700-3,000 m. and in Khasi and Jaintia hills up to 1,500 m.

Action: Plant—astringent and antilithic. Used for healing wounds. A decoction of the plant is prescribed against profuse menses, bloody stools, haemorrhages and ulcers in urinary passages. The whole herb is used in traditional chinese medicine for the treatment of arthritis.

The plant contains ursolic acid, chi- maphilin, hyperin, quercetin, myri- cetin and gallic acid. Chimaphilin and ursolic acid inhibit carrageenan- induced oedema in rat paw. Other constituents act as protective antioxi- dants.... pyrola rotundifolia

Pyrrha

(Greek) In mythology, Pandora’s daughter... pyrrha

Pyrrolizidine Alkaloid

A type of alkaloid found in many plants of the Composite and Borage families, once termed a Senecio alkaloid. Some of the pyrrolizidine group have been shown to cause several types of liver degeneration and blood vessel disorders. Several deaths have been attributed to improperly identified plant usage of a Senecio, and some of the desert Boraginaceae annuals and Senecio annuals are overtly toxic. Young leaves and spring roots of Comfrey hybrids should be avoided as well. Not all PAs are toxic, but those that are can produce spontaneous necrosis in the liver hepatocytes of a perfectly healthy person.... pyrrolizidine alkaloid

Pythia

(Greek) A prophetess; in mythology, a priestess of Apollo

Pythiah, Pythea, Pytheah, Pythiya, Pythiyah... pythia

Reference Population

The base population from which a sample is drawn at the time of initial sampling. The standard against which a population that is being studied can be compared. See “population”.... reference population

Risk Pooling

The practice of bringing several risks together for insurance purposes in order to balance the consequences of the realization of each individual risk.... risk pooling

Roscoea Procera

Wall.

Family: Zingiberaceae.

Habitat: The Himalayas at altitudes of 1,500-2,100 m, in grassy slopes.

Ayurvedic: Kaakoli, Kshira-Kaakoli.

Action: Tuberous root—revitalizing tonic, age-sustainer; used in restorative tonics.

One of the ingredients of the "Eight Tonic Herbs" (Ashta-varga) of Ayurvedic medicine.... roscoea procera

Pyrus Communis

Linn.

Family: Rosaceae.

Habitat: Distributed in the temperate regions of Europe and West Asia. Grown in Punjab and Kashmir.

English: Common or European Pear.

Folk: Bagu-goshaa, Babbu-goshaa.

Action: Fruits—a good source of pectin, help in maintaining a desirable acid balance in the body. Recommended to patients suffering from diabetes because of low sucrose content; and included in low antigen content diets to alleviate the symptoms in the management of immune-mediated disease.

Fresh pear juice exhibited good activity against Micrococcus pyogenes var. aureus and Escherichia coli.

An aqueous extract of the leaves was active against some strains of E. coli.

The leaves contain arbutin, iso- quercitrin, sorbitol, ursolic acid, astra- galin and tannin (0.8-2.9%). The bark contains friedelin, epifriedelanol and beta-sitosterol. Phloridzin is present in the root bark.

The plant extract controls the development of freckles and blemishes on the skin and prevents melanin formation. It finds application in skin- lightening creams.... pyrus communis

Quality Assessment And Performance Improvement Programme (qapi)

QAPI establishes strategies for promoting high quality health care. First, each organization must meet certain required levels of performance when providing specific health care and related services. Second, organizations must conduct performance improvement projects that are outcome-oriented and that achieve demonstrable and sustained improvement in care and services. It is expected that an organization will continuously monitor its own performance on a variety of dimensions of care and services, identify its own areas for potential improvement, carry out individual projects to undertake system interventions to improve care, and monitor the effectiveness of those interventions.... quality assessment and performance improvement programme (qapi)

Rattan Palm

Calamus species

Description: The rattan palm is a stout, robust climber. It has hooks on the midrib of its leaves that it uses to remain attached to trees on which it grows. Sometimes, mature stems grow to 90 meters. It has alternate, compound leaves and a whitish flower.

Habitat and Distribution: The rattan palm is found from tropical Africa through Asia to the East Indies and Australia. It grows mainly in rain forests.

Edible Parts: Rattan palms hold a considerable amount of starch in their young stem tips. You can eat them roasted or raw. In other kinds, a gelatinous pulp, either sweet or sour, surrounds the seeds. You can suck out this pulp. The palm heart is also edible raw or cooked.

Other Uses: You can obtain large amounts of potable water by cutting the ends of the long stems (see Chapter 6). The stems can be used to make baskets and fish traps.... rattan palm

Reconstructive (plastic) Surgery

Reconstructive surgery on the skin and underlying tissues that have been damaged or lost as a result of disease or injury. Congenital malformations are also remedied using reconstructive surgery. Surgeons graft healthy skin from another part of the body to repair skin damaged or destroyed by burns or injuries. New techniques are under development for growing new skin in the laboratory to be used in reconstructive surgery. Surgeons also repair damage using skin ?aps prepared in another part of the body – for example, a skin ?ap from the arm may be used to repair a badly injured nose or face. Reconstructive surgery is also used to repair the consequences of an operation for cancer of, say, the neck or the jaw. Plastic surgeons undertake cosmetic surgery to improve the appearance of noses, breasts, abdomens and faces.... reconstructive (plastic) surgery

Salmon Patches

See NAEVUS – Naevus simplex.... salmon patches

Saw Palmetto

Saw palmetto improves the actions of other herbs, particularly those that support the prostate gland (such as sarsaparilla), enabling optimal sexual functioning.... saw palmetto

Scrivener’s Palsy

Another name for writer’s cramp (see MUSCLES, DISORDERS OF).... scrivener’s palsy

Scrombotoxin Poisoning

This occurs from eating poorly preserved scromboid ?sh such as tuna, mackerel and other members of the mackerel family. In such ?sh, a toxic histamine-like substance is produced by the action of bacteria or histidine, a normal component of ?sh ?esh. This toxin produces nausea, vomiting, headache, upper abdominal pain, di?culty in swallowing, thirst, itching and sometimes URTICARIA. The condition settles as a rule in 12 hours. ANTIHISTAMINE DRUGS sometimes ameliorate the condition.... scrombotoxin poisoning

Seasonal Prevalence

The number of cases of infection in relation to the unit of population in which they occur (a static measure) at different times of the year.... seasonal prevalence

Regulation Of Health Professions

Professional sta? working in health care are registered with and regulated by several statutory bodies: doctors by the GENERAL MEDICAL COUNCIL (GMC); dentists by the GENERAL DENTAL COUNCIL; nurses and midwives by the Council for Nursing and Midwifery, formerly the UK Central Council for Nursing, Midwifery and Health Visiting (see NURSING); PHARMACISTS by the Royal Pharmaceutical Society; and the professions supplementary to medicine (chiropody, dietetics, medical laboratory sciences, occupational therapy, orthoptics, physiotherapy and radiography) by the Council for Professions Supplementary to Medicine. In 2002, the Council for the Regulation of Health Care Professions was set up as a statutory body that will promote cooperation between and give advice to existing regulatory bodies, provide a quality-control mechanism, and play a part in promoting the interests of patients. The new Council is accountable to a Select Committee of Parliament and is a non-ministerial government department similar in status to the FOOD STANDARDS AGENCY. It has the right to scrutinise the decisions of its constituent bodies and can apply for judicial review if it feels that a judgement by a disciplinary committee has been too lenient.... regulation of health professions

Rhamnus Procumbens

Edgew.

Family: Rhamnaceae.

Habitat: Western Himalayas from Simla to Kumaon at an altitude of 2,300 to 2,600 m.

English: Buckthorn (related species).

Action: Plant—anticonvulsant, anti-inflammatory, anti-ulcer.

The plant contains kaempferol, kaempferol-7-O-methyl ether and kaempferol-4'-O-methyl ether.

The ethyl acetate soluble portion of the alcoholic extract showed anti- nociceptive, anticonvulsant and anti- inflammatory activity. Kaempferol-4'- O-methyl ether was found to exhibit central nervous system depressant, cardiac stimulant, antispasmodic and anti-inflammatory activity

The plant also contain emodin, which exhibited cardiac and intestinal stimulant, central nervous system depressant and analgesic activity in experimental animals.... rhamnus procumbens

Rhamnus Purshiana

DC.

Synonym: Frangulapurshiana (DC) A. Grey.

Family: Rhamnaceae.

Habitat: Native to Europe; introduced in Kashmir, Himachal Pradesh, Bhutan and the Nilgiris.

English: Buckthorn (related species), Cascara Sagrada, Sacred Bark.

Action: Bark—stool-softener, non-habit forming stimulant laxative, pancreatic stimulant. Used for dyspepsia and habitual constipation.

Key application: In occasional constipation. (German Commission E, ESCOP, WHO.) As a stimulant laxative. (The British Herbal Pharmacopoeia.)

The bark contains up to 10% an- thraquinone glycosides, consisting of the cascarosides A, B, C and D, about 70% of the total; other glycosides in minor concentrations include barbaloin, frangulin, chrysanol, glycosides based on emodin, aloe-emodin, emodin- oxanthrone and chrysophanol; dianthrones, and free aglycones.

The cascarosides act on large intestines and stimulate peristalsis. The emodin exhibits antispasmodic activity in isolated rat intestine. Its anti- inflammatory and antiseptic action was also demonstrated.

Rhamnus catharticus Linn., is equated with common Buckthorn, R. purpurea Edgew. with Purple Buckthorn. R. purpurea is found in the Himalayas from Kashmir to Nepal.

Dried bark of Rhamnus frangula L. (Alder Buckthorn) and dried ripe berries of Ramnus catharticus are also used against constipation. (German Commission E, WHO.)

Long term use or excessive amounts may cause albuminuria, haematuria, slowing ofintestinal transit and cardiac irregularities. (Sharon M. Herr.)

Rhamnus triquetra Brandis (known as Gudlei, Fagoraa, Gardhan in Punjab; Gaunt in Garhwal and Kumaon and Katheraa in Jaunsar) is found in the Himalayas from Kashmir to Nepal. The bark is used as a tonic, astringent and deobstruent. Kaempferol, its 7-O- methyl ether and 4'-O-methyl ether, physcion-8 beta-D-glucoside, emodin and its 8 beta-D-glucoside were isolated from the whole plant. Emodin exhibited CNS depressant activity. (Fi- toterapia, 65, 1994.) The plant exhibited significant anti-inflammatory and a nonspecific antispasmodic activity. It induced cardio-stimulation which might be due to the endogenous release of catecholamines.

Rhamnus napalensis Wall. ex M. Laws. (known as Archal in Nepal; Biringa and Birringguli in Assam) is found in eastern Himalayas and the hills and plains ofAssam, Bihar, Orissa, Madhya Pradesh and northern Andhra Pradesh, ascending up to an altitude of 2,000 m. The fruit, pounded and macerated in vinegar, is prescribed for the treatment of herpes.... rhamnus purshiana

Self-poisoning

See POISONS.... self-poisoning

Self-rated Health Status / Perceived Health Status

Health status is usually obtained from survey data by asking the respondent if his/her health is excellent, very good, good, fair or poor (or similar questions).... self-rated health status / perceived health status

Service Package

See “care package”.... service package

Service Plan

See “care plan”.... service plan

Short-term Supportive Psychotherapy

is aimed at stabilising and strengthening the psychological defence mechanisms of those patients who are confronted by a crisis which threatens to overwhelm their ability to cope, or who are struggling with the aftermath of major life events.... short-term supportive psychotherapy

Sibbaldia Parviflora

Willd.

Family: Rosaceae.

Habitat: Garwal region.

Ayurvedic: Bajradanti. Barleria prionitis L. and Potentilla arbuscula D. Don. are also used as Bajradanti.)

Action: Used as a tooth powder for strengthening gums and teeth.... sibbaldia parviflora

Single Assessment Process

The process whereby a person is assessed for care needs using one form/mechanism so that agencies do not duplicate each other’s assessment.... single assessment process

Rhus Parviflora

Roxb.

Family: Anacardiaceae.

Habitat: Dry hot slopes of the Himalayas from Punjab to Nepal and in the hills of Madhya Pradesh and South India.

English: Sumach.

Ayurvedic: Tintidi, Tintindeeka.

Unani: Sumaaq.

Folk: Raitung, Tung (Kumaon).

Action: Fruit juice—vermifuge.

The leaves contain the flavonoids, myricetin, quercetin and kaempferol and their 3-O-rhamnosides; the stems and leaves also gave hentriacontane, hentriacontanol, beta-sitosterol, ligno- ceric acid and iso-rhamnetin-3-alpha- L-arvinoside.

Smooth Sumach and Sweet Sumach (Canada and USA) are equated with Rhus glabra L. and R. aromatica Ait. Smooth Sumach is astringent and diuretic. Sweet Sumach is used for its antidiabetic activity; the root bark is used for irritable bladder, bed-wetting and urinary incontinence. (Natural Medicines Comprehensive Database, 2007.)

Dosage: Fruit—3-6 g powder. (CCRAS.)... rhus parviflora

Robinia Pseudoacacia

Linn.

Family: Fabaceae.

Habitat: Western Himalayas and Jammu & Kashmir.

English: Locust tree, False Acacia, Robinia, Black Locust.

Action: Leaves—laxative, antispas- modic (an infusion is prescribed in digestive disorders). Flowers— diuretic, antispasmodic.

The bark, leaves and roots contain a toxalbumin, robin (1.6% in the bark), which resembles ricin present in the castor seed. The bark also contains a glucoside robinitin (3%), syringin, tannin (up to about 7.0%). Inner bark contains amygdalin and urease.

The leaves are rich in calcium, phosphorus and potash. The presence of glycosides, acaciin, apigenin-7-bioside, apigenin-7-trioside and indican, have also been reported.

The flowers are powerfully diuretic due to a glycoside, robinin. Flowers also contain l-asparagine.

The roots are rich in asparagine, also contain robin. Root bark, if taken in excess, is emetic and purgative.

The bark and young shoots are poisonous to livestock.... robinia pseudoacacia

Rungia Pectinata

(L.) Nees.

Synonym: R. parviflora (L.) Nees var. pectinata C. B. Clarke. Justicia pectinata L.

Family: Acanthaceae.

Habitat: Throughout India, in waste places and hedges.

Ayurvedic: Parpata (as adulterant).

Siddha/Tamil: Punakapundu.

Action: Leaves—juice is aperient, febrifuge, refrigerant; bruised leaves are applied externally to disperse swellings. Root—febrifuge. The juice of leaves is given to children suffering from smallpox.... rungia pectinata

Saccolabium Papillosum

Lindl.

Family: Orchidace.

Habitat: The outer range of Himalayas from Uttar Pradesh eastwards to Sikkim and Assam.

Ayurvedic: Naakuli (substitute), Vrkshaadani (var.).

Folk: Raasanaa, Naakuli, Gandha- lataa.

Action: Roots—used for rheumatism.

An alkaloid and a bitter resin has been reported in the plant.

Roots are used as a substitute for Sarsaparilla (Hemidesmus indicus).... saccolabium papillosum

Single Point Of Entry

A local or regional access point where older persons receive information, assessment of needs, care planning, referrals to health and social services and, in some systems, authorization of services for home care, community-based care or residential care facilities.... single point of entry

Solo Practice

The practice of a health occupation as a self-employed individual.... solo practice

Sago Palm

Metroxylon sagu

Description: These palms are low trees, rarely over 9 meters tall, with a stout, spiny trunk. The outer rind is about 5 centimeters thick and hard as bamboo. The rind encloses a spongy inner pith containing a high proportion of starch. It has typical palmlike leaves clustered at the tip.

Habitat and Distribution: Sago palm is found in tropical rain forests. It flourishes in damp lowlands in the Malay Peninsula, New Guinea, Indonesia, the Philippines, and adjacent islands. It is found mainly in swamps and along streams, lakes, and rivers.

Edible Parts: These palms, when available, are of great use to the survivor. One trunk, cut just before it flowers, will yield enough sago to feed a person for 1 year. Obtain sago starch from nonflowering palms. To extract the edible sage, cut away the bark lengthwise from one half of the trunk, and pound the soft, whitish inner part (pith) as fine as possible. Knead the pith in water and strain it through a coarse cloth into a container. The fine, white sago will settle in the container. Once the sago settles, it is ready for use. Squeeze off the excess water and let it dry. Cook it as pancakes or oatmeal. Two kilograms of sago is the nutritional equivalent of 1.5 kilograms of rice. The upper part of the trunk’s core does not yield sage, but you can roast it in lumps over a fire. You can also eat the young sago nuts and the growing shoots or palm cabbage.

Other Uses: Use the stems of tall sorghums as thatching materials.... sago palm

Salvadora Persica

Linn.

Synonym: S.persica L.var. wightiana Verde. S. indica Wt.

Family: Salvadoraceae.

Habitat: Arid regions, on saline lands and in coastal regions.

English: Mustard tree. Salt Bush tree, Tooth Brush tree.

Ayurvedic: Pilu (smaller var.), Pilukaa, Sransi, Angaahva, Tikshna- vrksha.

Unani: Miswaak, Araak.

Siddha: Perungoli.

Action: Fruit—carminative (used in biliousness), deobstruent (used for rheumatism, tumours, splenomegaly), diuretic, lithotriptic. Leaves—decoction used for cough and asthma, poultice in painful piles and tumours; juice in scurvy. Flowers—stimulant, laxative. Applied in painful rheumatic conditions. Seeds—diuretic; purgative; fatty oil applied locally on rheumatic swellings. Root bark—topically vesicant. Bark—emmenagogue, ascarifuge, febrifuge. Biological activity of stem bark—spasmolytic. Plant—anti-inflammatory, hypoglycaemic, antibacterial.

The root gave elemental gamma- monoclinic sulphur, benzyl glucosino- late, salvadourea (a urea derivative), m-anisic acid and sitosterol. Benzyl isothiocyanate, isolated from the root, exhibits antiviral activity against Herpes simplex virus-1 which affects oral region. (The root is used in many parts of the world as a tooth brush.) Root bark and stem bark contain trimethy- lamine. Myristic, lauric and palmitic acids are the major acid components of the seed fat.

Dosage: Fruit—3-6 g powder; 50100 ml decoction. (CCRAS.)... salvadora persica

Salvia Plebeia

R. Br.

Family: Labiatae; Lamiaceae.

Habitat: Throughout the plains of India, up to 1,500 m in the hills.

Ayurvedic: Samudrashosha, Kammarkasa.

Folk: Bhuu-Tulasi.

Action: Plant—diuretic, an- thelmintic, astringent, demulcent. Leaves—used for toothache. Seeds—mucilaginous, used for diarrhoea, leucorrhoea, menorrhagia and haemorrhoids.

The plant contains flavones—nepe- tin and hispidulin and their gluco- sides. Flowers also contain nepetin. Sitosterol and oleanolic acid are also present. The seeds yield secoisolari- ciresinol diester.... salvia plebeia

Screw Pine

Pandanus species

Description: The screw pine is a strange plant on stilts, or prop roots, that support the plant above-ground so that it appears more or less suspended in midair. These plants are either shrubby or treelike, 3 to 9 meters tall, with stiff leaves having sawlike edges. The fruits are large, roughened balls resembling pineapples, but without the tuft of leaves at the end.

Habitat and Distribution: The screw pine is a tropical plant that grows in rain forests and semievergreen seasonal forests. It is found mainly along seashores, although certain kinds occur inland for some distance, from Madagascar to southern Asia and the islands of the southwestern Pacific. There are about 180 types.

Edible Parts: Knock the ripe fruit to the ground to separate the fruit segments from the hard outer covering. Chew the inner fleshy part. Cook fruit that is not fully ripe in an earth oven. Before cooking, wrap the whole fruit in banana leaves, breadfruit leaves, or any other suitable thick, leathery leaves. After cooking for about 2 hours, you can chew fruit segments like ripe fruit. Green fruit is inedible.... screw pine

Sweet Potato

See Batata.... sweet potato

Tacca Pinnatifida

Forst. f.

Synonym: T. leontopetaloides (Linn.) Kuntze.

Family: Compositae; Asteraceae.

Habitat: Native to Mexico; cultivated in gardens all over India.... tacca pinnatifida

Tissue Plasminogen Activator (tpa, Tpa)

A natural PROTEIN that occurs in the body. It has the property of breaking down a THROMBUS in a blood vessel (see THROMBOLYSIS). It is e?ective only in the presence of FIBRIN and activates plasminogen, which occurs normally on the surface of the ?brin. TPA is an important thrombolytic treatment immediately after a myocardial infarction (see HEART, DISEASES OF).... tissue plasminogen activator (tpa, tpa)

Shellfish Poisoning

In the United Kingdom this occurs in two main forms. Shell?sh may be the cause of typhoid fever (see ENTERIC FEVER) as a result of their contamination by sewage containing the causative organism. They may also be responsible for what is known as paralytic shell?sh poisoning. This is caused by a toxin, or poison, known as saxotoxin, which is present in certain planktons which, under unusual conditions, multiply rapidly, giving rise to what are known as ‘red tides’. In these circumstances the toxin accumulates in mussels, cockles and scallops which feed by ?ltering plankton. The manifestations of such poisoning are loss of feeling in the hands, tingling of the tongue, weakness of the arms and legs, and di?culty in breathing. There is also growing evidence that some shell?sh poisoning may be due to a virus infection. (See also FOOD POISONING.)... shellfish poisoning

Shepherd`s Purse Tea

Shepherd’s Purse tea is made from a medicinal plant used traditionally in easing menstrual symptoms, treating water retention, dysentery and eye afflictions. It has the property of enhancing coagulation and constricting blood vessels. The plant has small white flowers, pointed, arrow-shaped leaves and gets its name from the resemblance of its heart-shaped seed-pouches with an old-fashioned leather purse. Shepherd’s Purse Tea Brewing In order to brew Shepherd’s Purse tea, you must bring 300 ml of water to a boil, add 10 grams of the herb and let it steep for 30 minutes, then drain it. Shepherd’s Purse Tea Health Benefits Shepherd’s Purse tea is reputed for its ability to stop internal and external bleeding. In Europe, people have been using the beverage to stop stomach haemorrhage and to treat urinary tract bleeding. Midwives used it to prevent post-partum bleeding. Shepherd’s Purse tea has anti-inflammatory properties which may account for its traditional use in the treatment of haemorrhoids and wounds. Shepherd’s Purse tea is also an effective natural remedy for blood pressure problems or irregular heartbeat. It can be applied externally on wounds and burns. Shepherd’s Purse Tea Side Effects There are no reported side effects ofShepherd’s Purse tea consumption, but it is advisable to ask the opinion of a specialist before drinking it, especially if you are taking any medications. Excessive intake of this beverage may interfere with blood pressure and thyroid drugs. Pregnant women are not advised to consume Shepherd’s Purse tea, because it can cause uterine contractions and miscarriage. People suffering from kidney or liver diseases should also avoid Shepherd’s Purse tea.... shepherd`s purse tea

Shepherd's Purse

Capsella bursa-pastoris. N.O. Cruciferae.

Synonym: Mother's Heart, Pickpocket, Shepherd's Sprout.

Habitat: Hedgerows, meadows, waysides, waste places.

Features ? Stem erect, slightly branched, varies from a few inches to over a foot in height with the richness of the soil. Leaves irregular-lanceolate, also differing largely in size and shape with the plant's environment. Identifiable by the triangular seed vessels, thought to resemble in shape the purses of olden days. Blossoms during most of the year ; flowers very small, white, short-stalked. Odour unpleasant.

Part used ? Herb.

Action: Diuretic, stimulant.

The infusion of 1 ounce to 1 pint is administered in wineglass doses for kidney complaints and dropsy. Often combined with Pellitory-of-the-Wall and Juniper berries.... shepherd's purse

Spiritual Pain

Spiritual pain is what may be felt when one of a person’s four key spiritual relationships (with other people, with oneself, with the world around, or with ‘Life’ itself) is traumatised or broken. A bad trauma in one of the ?rst three relationships can lead to damage to the last of them – that of the relationship with Life itself. For example, a wife deserted by her husband for another woman may not only feel devastated by the loss of her partner around the place, but may also feel a pain caused by the shattering of her beliefs about life (about faithfulness, hope, love, security, etc.). It is as if there is a picture at the centre of each person of what life should be about – whether or not held in a frame by a belief in God; this picture can be smashed by a particular trauma, so that nothing makes sense any more. The individual cannot get things together; everything loses its meaning. This shattering of someone’s picture of life is the source of the deepest pain in any spiritual trauma. The connection is often made between spiritual pain and meaninglessness. If the shattering of the picture, on the other hand, is done by the individual – for instance, by breaking his or her own moral or religious code – the pain may take the form of guilt and associated feelings. Hence, the therapist will be intent upon helping a client to recognise and come to terms with this ‘pain beneath the pain’.... spiritual pain

Trendelenberg Position

This is a steep head-down tilt so that the patient’s pelvis and legs lie above the heart. It is used to improve access, and to limit blood loss, during surgery to the pelvis. It has been used to treat shocked patients (see SHOCK), but, as the position increases pressure on the DIAPHRAGM and embarrasses breathing, raising the legs by themselves is better.... trendelenberg position

Urtica Parviflora

Roxb.

Family: Urticaceae.

Habitat: Temperate Himalayas and the Nilgiris.

Ayurvedic: Vrishchhiyaa-shaaka.

Folk: Shisuun (Kumaon).

Action: Roots—employed for the treatment of fractures and dislocations. Leaves and inflorescences—prescribed as a tonic and as a cleaning agent after parturition.... urtica parviflora

Valeriana Pyrolaefolia

Decne.

Family: Valerianaceae.

Habitat: The temperate Himalayas from Kashmir to Bhutan.

Ayurvedic: Dhyaamaka (including among aromatic drugs of Jatamansi group.)

Folk: Sugandhabaalaa.

Action: Used as V. jatamansi.... valeriana pyrolaefolia

Spondias Pinnata

(Linn. f.) Kurz.

Synonym: S. mangifera Willd.

Family: Anacardiaceae.

Habitat: A small, aromatic tree occurring wild or grown throughout the country for edible fruits.

English: Hog-Plum, Wild Mango. Great Hog-Plum is equated with S. cytherea Sonn, synonym S. dulcis Soland. ex Forst. f.

Ayurvedic: Aamraataka, Aamraata, Aamadaa, Madhuparni, Kundalini, Kapitana, Markataamra.

Siddha/Tamil: Mambulichi, Kat- tuma.

Folk: Jangali Aam.

Action: Fruits, leaves, bark— astringent, antidysenteric, anti- speptic, antiscorbutic. Bark paste applied externally to articular and muscular rheumatism. Root—used for regulating menstruation.

The Ayurvedic Pharmacopoeia ofIn- dia recommends stem bark in haem- orrhagic diseases.

The fruit contains beta-amyrin, olea- nolic acid and amino acids—glycine, cystine, serine, alanine and leucine; polysaccharides are also present.

Aerial parts gave lignoceric acid, 24-methylenecycloartanone, stigmast- 4-en-3-one, beta-sitosterol and its glu- coside.

Dosage: Stem bark—5-10 g powder for decoction (API, Vol. II); 1-3 g powder (API, Vol. III).... spondias pinnata

Stachys Palustris

Linn.

Family: Labiatae; Lamiaceae.

Habitat: Kashmir, grows in damp places, at altitudes of 1,500-1,800 m.

English: Marsh, Woundwort (purple-flowered), Allheal. (In Western herbal, Allheal is equated with Prunella vulgaris.)

Action: Haemostatic, sedative, antiseptic, antispasmodic, vulnerary. Used for haemorrhages, gout, cramp, vertigo; applied as poultice to wounds.

The herb contains iridoids, harpa- gide and acetyl harpagide; flavonoids based on isoscutellarein and oroxylin A.... stachys palustris

Stereospermum Personatum

(Hassk.) D. Chatterjee.

Synonym: S. Chelonoides (Linn. f.) DC. (now S. Colais). S. tetragonum A. DC.

Family: .

Habitat: Throughout India, especially in the moist regions.

English: Trumpet Flower, Yellow Snake tree.

Ayurvedic: Paatalaa, Paatali, Paata- lai, Krishna-vrantaa, Madhu-duuti,

Kaama-duuti, Ativallabhaa, Taam- rapushpi, Kuberaakshi. Amoghaa, Kumbhipushpi, Ambuvaasini. Copper-red-flowered var., known as Taamrapushpi, is equated with S. suaveolens (Paatalaa) and the white- flowered one with S. chelenoides. (Paatalai).

Siddha/Tamil: Paadiri.

Action: The Ayurvedic Pharmacopoeia of India recommends the root of Paatalaa in lipid disorders; the stem bark in oedema and retention of urine.

The white-flowered var. purifies blood, increases appetite and is prescribed for vomiting, hiccough, thirst, oedema and inflammatory chest diseases.

The copper-red-flowered var. is prescribed in difficult breathing, vomiting, oedema, flatus and high fever.

Ethanolic extract of the plant showed hypoglycaemic and anticancer activity experimentally.

A decoction of S. personatum root is prescribed for asthma and cough; of the leaves in chronic dyspepsia. A decoction of the root and leaves is credited with antipyretic properties. The bark exhibited antibacterial and antitubercular properties.

A decoction of S. suaveolens roots is prescribed for intermittent and puerperal fevers, inflammatory affections of the chest. Extracts of the plant contain lapachol.

The leaves of S. chelonoides contain a flavone, stereolensin. The bark gave an iridoid glycoside; the root bark gave n-triacontanol and beta- sitosterol; the root heartwood gave la- pachol, dehydro-alpha-lapachone and dehydrotectol. Ceryl alcohol, palmitic, stearic and oleic acids were isolated from the root. Lapachol exhibited cy- totoxic activity.

Dosage: Stem bark (white-flowered var.)—3-6 g powder. (API, Vol. IV.) Root (red-flowered var.)—5-10 g powder. (API, Vol. III.) more effective. Crude extract is used for filaria.

The Central Drug Research Institute, Lucknow, has developed an an- tifilarial drug from the crude extract of stem. The stem bark is reported to cure filarial lymphangitis, lym- phoedema, chyluria caused by filaria- sis.

Dosage: Stem bark—1-3 g powder. (API, Vol. III.)... stereospermum personatum

Vasodilation, Peripheral

The increase of blood into the skin, resulting from the relaxation of the small arterioles that lead into the capillary beads at the edges of the body. This is a gentle way to lessen early high blood pressure, decreasing the difficulty of pushing columns of arterial blood through miles of capillaries.... vasodilation, peripheral

Very Old People

Persons aged 75 years and over.... very old people

Viola Patrinii

Ging.

Family: Violaceae.

Habitat: The Himalayas, Eastern and Western Ghats.

Unani: Banafashaa (related species).

Action: Dried flowers—used for coughs and colds. Herb— bruised and applied to ulcers; also prescribed in syphilis and scrofula. (In Chinese medicine, recommended against cancerous growths.)... viola patrinii

Viola Pilosa

Blume.

Family: Violaceae.

Habitat: Kashmir to Sikkim and Nilgiri hills at 1,500-2,100 m.

Unani: Banafashaa (related species)

Folk: Thungtu (Kumaon).

Action: Uses same as those of V odorata. A medicinal oil of Unani medicine, Roghan-e-Banafashaa, is prepared from the plant. Flowers, as tea, are used for treating headache.

Active principle of the herb is an alkaloid, violine.... viola pilosa

Steroids, Plant

The previous subject is obviously an endless one, but as this is the glossary of an herbal nature, let me assure you, virtually no plants have a direct steroid hormone-mimicking effect. There are a few notable exceptions with limited application, like Cimicifuga and Licorice. Plant steroids are usually called phytosterols, and, when they have any hormonal effect at all, it is usually to interfere with human hormone functions. Beta sitosterol, found in lots of food, interferes with the ability to absorb cholesterol from the diet. Corn oil and legumes are two well-endowed sources that can help lower cholesterol absorption. This is of only limited value, however, since cholesterol is readily manufactured in the body, and elevated cholesterol in the blood is often the result of internal hormone and neurologic stimulus, not the diet. Cannabis can act to interfere with androgenic hormones, and Taraxacum phytosterols can both block the synthesis of some new cholesterol by the liver and increase the excretion of cholesterol as bile acids; but other than that, plants offer little direct hormonal implication. The first method discovered for synthesizing pharmaceutical hormones used a saponin, diosgenin, and a five-step chemical degradation, to get to progesterone, and another, using stigmasterol and bacterial culturing, to get to cortisol. These were chemical procedures that have nothing to do with human synthesis of such hormones, and the plants used for the starting materials-Mexican Wild Yam, Agave, and Soy were nothing more than commercially feasible sources of compounds widely distributed in the plant kingdom. A clever biochemist could obtain testosterone from potato sterols, but no one would be likely to make the leap of faith that eating potatoes makes you manly (or less womanly), and there is no reason to presume that Wild Yam (Dioscorea) has any progesterone effects in humans. First, the method of synthesis from diosgenin to progesterone has nothing to do with human synthesis of the corpus luteum hormone; second, oral progesterone has virtually no effect since it is rapidly digested; and third, orally active synthetic progesterones such as norethindrone are test-tube born, and never saw a Wild Yam. The only “precursor” the ovaries, testes and adrenal cortices EVER need (and the ONLY one that they can use if synthesizing from scratch) is something almost NONE of us ever run out of...Low Density Cholesterol. Unless you are grimly fasting, anorectic, alcoholic, seriously ill or training for a triathlon, you only need blood to make steroid hormones from. If hormones are off, it isn’t from any lack of building materials...and any product claiming to supply “precursors” better contain lard or butter (they don’t)...or they are profoundly mistaken, or worse. The recent gaggle of “Wild Yam” creams actually do contain some Wild Yam. (Dioscorea villosa, NOT even the old plant source of diosgenin, D. mexicana...if you are going to make these mistakes, at least get the PLANT right) This is a useful and once widely used antispasmodic herb...I have had great success using it for my three separate bouts with kidney stones...until I learned to drink more water and alkalizing teas and NEVER stay in a hot tub for three hours. What these various Wild Yam creams DO contain, is Natural Progesterone. Although this is inactive orally (oral progesterone is really a synthetic relative of testosterone), it IS active when injected...or, to a lesser degree, when applied topically. This is pharmaceutical progesterone, synthesized from stigmasterol, an inexpensive (soy-bean oil) starting substance, and, although it is identical to ovarian progesterone, it is a completely manufactured pharmaceutical. Taking advantage of an FDA loophole (to them this is only a cosmetic use...they have the misguided belief that it is not bioactive topically), coupled with some rather convincing (if irregular) studies showing the anti-osteoporotic value of topical progesterone for SOME women, a dozen or so manufacturers are marketing synthetic Natural Progesterone for topical use, yet inferring that Wild Yam is what’s doing good. I am not taking issue with the use of topical progesterone. It takes advantage of the natural slow release into the bloodstream of ANY steroid hormones that have been absorbed into subcutaneous adipose tissue. It enters the blood from general circulation the same way normal extra-ovarian estradiol is released, and this is philosophically (and physiologically) preferable to oral steroids, cagily constructed to blast on through the liver before it can break them down. This causes the liver to react FIRST to the hormones, instead of, if the source is general circulation, LAST. My objection is both moral and herbal: the user may believe hormonal effects are “natural”, the Wild Yam somehow supplying “precursors” her body can use if needed, rejected if not. This implies self-empowerment, the honoring of a woman’s metabolic choice...something often lacking in medicine. This is a cheat. The creams supply a steady source of pharmaceutical hormone (no precursor here) , but they are being SOLD as if the benefits alone come from the Wild Yam extract, seemingly formulated with the intent of having Wild Yam the most abundant substance so it can be listed first in the list of constituents. I have even seen the pharmaceutical Natural Progesterone labeled as “Wild Yam Progesterone” or “Wild Yam Estrogen precursor” or, with utter fraud, “Wild Yam Hormone”. To my knowledge, the use of Mexican Yam for its saponins ceased to be important by the early 1960’s, with other processes for synthesizing steroids proving to be cheaper and more reliable. I have been unable to find ANY manufacturer of progesterone that has used the old Marker Degradation Method and/or diosgenin (from whatever Dioscorea) within the last twenty years. Just think of it as a low-tech, non invasive and non-prescription source of progesterone, applied topically and having a slow release of moderate amounts of the hormone. Read some of the reputable monographs on its use, make your choice based solely on the presence of the synthetic hormone, and use it or don’t. It has helped some women indefinitely, for others it helped various symptoms for a month or two and then stopped working, for still other women I have spoken with it caused unpleasant symptoms until they ceased its use. Since marketing a product means selling as much as possible and (understandably) presenting only the product’s positive aspects, it would be better to try and find the parameters of “use” or “don’t use” from articles, monographs, and best of all, other women who have used it. Then ask them again in a month or two and see if their personal evaluation has changed. If you have some bad uterine cramps, however, feel free to try some Wild Yam itself...it often helps. Unless there is organic disease, hormones are off is because the whole body is making the wrong choices in the hormones it does or doesn’t make. It’s a constitutional or metabolic or dietary or life-stress problem, not something akin to a lack of essential amino acids or essential fatty acids that will clear up if only you supply some mythic plant-derived “precursor”. End of tirade.... steroids, plant

Strychnos Potatorum

Linn.f.

Family: Loganiaceae; Strychnaceae.

Habitat: Forests of West Bengal, Central and South India, up to 1,200 m.

English: Clearing Nut tree.

Ayurvedic: Kataka, Katakaphala, Payah-prasaadi, Chakshushya, Nirmali.

Unani: Nirmali.

Siddha/Tamil: Thettran, Thetrankot- tai.

Action: Seed—antidiabetic, antidysenteric, emetic.

Mannogalactan from seeds reduces cholesterol and triglycerides (one-tenth and one-fifth when compared to clofi- brate). Seeds are also applied to abscesses, and venereal sores (internally in gonorrhoea). Fruits—antidiabet- ic; antidysenteric, expectorant. (Pulp is used as a substitute for ipecacuanha.)

The Ayurvedic Pharmacopoeia ofIn- dia recommends the seed in dysuria, polyuria, urolithiasis, also in epilepsy.

The seeds, leaves and trunk bark gave diabolin (major alkaloid) and acetyldiabolin. Seeds also gavebrucine, strychnine, novacine, icajine, oleanolic acid and its glycoside. Leaves and bark gave isomotiol, stigmasterol, campes- terol and sitosterol. Diabolin exhibits hypotensive activity.

A decoction of seeds is given to treat stammering.

The seeds resemble those of Nux- vomica but are non-poisonous. The ripe seeds are used for clearing muddy water.

Dosage: Seed—3-6 g. (API, Vol. IV.)... strychnos potatorum

Sugar Palm

Arenga pinnata

Description: This tree grows about 15 meters high and has huge leaves up to 6 meters long. Needlelike structures stick out of the bases of the leaves. Flowers grow below the leaves and form large conspicuous dusters from which the fruits grow.

Habitat and Distribution: This palm is native to the East Indies but has been planted in many parts off the tropics. It can be found at the margins of forests.

Edible Parts: The chief use of this palm is for sugar. However, its seeds and the tip of its stems are a survival food. Bruise a young flower stalk with a stone or similar object and collect the juice as it comes out. It is an excellent source of sugar. Boil the seeds. Use the tip of the stems as a vegetable.

CAUTION

The flesh covering the seeds may cause dermatitis.

Other Uses: The shaggy material at the base of the leaves makes an excellent rope as it is strong and resists decay.... sugar palm

Swertia Paniculata

Wall.

Synonym: Ophelia paniculata (Wall.) D. Don O. wallichii G. Don

Family: Gentianaceae.

Habitat: The Himalaya from Kashmir to Bhutan and in Lushai Hills in Mizoram at 1,500-2,400 m.

Action: Used as a substitute for Swertia chirayita.

The root gave xanthones (including swerchirin and bellidifolin); flavone- C-glycosides—swertisin and homoori- entin. The plant gave polyoxygenated xanthones and xanthone-O-glucosi- des; also a pentacyclic triterpenehed- eragenin. Aerial parts, in addition to xanthones, contain ursolic acid.... swertia paniculata

Symplocos Paniculata

(Thunb.) Miq.

Synonym: S. crataegoides Buch. Ham. ex Don. S. chinensis (Lour.) Druce. Prunus paniculatus Thunb.

Habitat: The Himalayas from Kashmir to Arunachal Pradesh and Assam; Khasi Hills at 1,0002,500 m.

English: Sapphire Berry.

Ayurvedic: Lodhra-Pattikaa.

Unani: Lodh Pathaani.

Action: Leaf—spasmolytic, antiviral, antiprotozoal, anthelmintic. Bark— used as a tonic for preventing abortion. Other uses same as of S. racemosa.

The water-soluble fraction from the bark has been reported to exhibit anti- oxytocic activity. Ethanolic extract of the leaves showed activity against Entamoeba histolytica strain STA, Ascaridia galli and Ranikhet-disease virus. It also affected blood pressure in dogs and cats, and showed activity on the ileum of guinea-pigs. The extract of stem also affected the blood pressure.

The leaf and stem are CVS active.... symplocos paniculata

Visiting Service / Visitor Programme

Through volunteers or community workers, a service providing companionship and support for older people who may be lonely and isolated.... visiting service / visitor programme

Water Plantain

Alisma plantago-aquatica

Description: This plant has small, white flowers and heart-shaped leaves with pointed tips. The leaves are clustered at the base of the plant.

Habitat and Distribution: Look for this plant in fresh water and in wet, full sun areas in Temperate and Tropical Zones.

Edible Parts: The rootstocks are a good source of starch. Boil or soak them in water to remove the bitter taste.

CAUTION

To avoid parasites, always cook aquatic plants.... water plantain

Water-hammer Pulse

The peculiarly sudden PULSE that is associated with incompetence of the AORTIC VALVE of the heart.... water-hammer pulse

Wax Plant

Protection... wax plant

Wild Pistachio

Pistacia species

Description: Some kinds of pistachio trees are evergreen, while others lose their leaves during the dry season. The leaves alternate on the stem and have either three large leaves or a number of leaflets. The fruits or nuts are usually hard and dry at maturity.

Habitat and Distribution: About seven kinds of wild pistachio nuts are found in desert, or semidesert areas surrounding the Mediterranean Sea to Turkey and Afghanistan. It is generally found in evergreen scrub forests or scrub and thorn forests.

Edible Parts: You can eat the oil nut kernels after parching them over coals.... wild pistachio

Tea For Back Pain

Back pain is usually an affection caused by both external and internal problems. Standing too long, pregnancy, weight lifting or pulmonary problems could cause severe back pains. Other than a prolonged pain localized in your back area, this affection could also interfere with your coronary and circulatory systems: the blood pressure is high and it’s hard for your heart to pump oxygen in your system. How a Tea for Back Pain Works A Tea for Back Pain’s main purpose is to make your body release enough endorphins to induce a state of calmness and well-being to your entire organism. In order to do that, a Tea for Back Pain must contain an important amount of nutrients, acids, volatile oils, antioxidants, enzymes and minerals (such as sodium, iron, magnesium and manganese). Efficient Tea for Back Pain An efficient Tea for Back Pain must show results as quickly as possible and be one hundred percent sure (when choosing an herbal treatment, always be well informed of the risks). If you don’t know which teas could have a positive effect on your health, here’s a list for guidance: - Ginger Tea – will bring relief to your pain and improve your general health in no time. You can also take it in case you’re suffering from anemia, asthenia, loss of appetite or headaches. However, in order to avoid other health complications, make sure you’re using a small amount of herbs when preparing this decoction. Otherwise, you might develop an acid foods and drinks intolerance. - Turmeric Tea – not very popular among Europeans, this Tea for Back pain acts as a great pain reliever, calming all your affected areas and restoring your general health in no time. You may also want to try it in case you’re suffering from inflammations, bruises, spreads, skin or digestive issues. Make sure you don’t drink more than 2 cups per day and everything will be fine. - Valerian Tea – used as a great sedative since ancient times, when the Greeks and the Romans drank a cup of it before every night, this Tea for Back Pain will nourish your nervous system and bring relief to your wounded areas. However, make sure you pay attention to the amount of tea you’re ingesting in order to avoid hallucinations and even death. Tea for Back Pain Side Effects When taken properly, these teas are generally safe. However, exceeding the number of cups recommended per day may lead to a series of affections, such as nausea, upset stomach, vomiting and even death. If you’ve been taking one of these teas for a while and you’ve noticed some unusual reactions from your body, ask for medical assistance immediately! If you have the green light from your doctor and there’s nothing that could interfere with your treatment, choose a Tea for Back Pain that fits best your needs and enjoy its health benefits!... tea for back pain

Tea For Blood Pressure

As a natural beverage, a cup of tea brings you many health benefits. One of them is related to blood pressure. Based on the type of tea you drink, it can help lower your blood pressure. Find out more about teas for blood pressure! Problems with blood pressure Blood pressure represents the pressure made by the circulating blood on the walls of the blood vessels. However, problems appear in the case of hypertension and hypotension. Hypertension is a medical condition caused by a high blood pressure, while hypotension is caused by a low blood pressure. Both can be treated with one of the various types of tea for blood pressure. Tea for high blood pressure If you’ve got problems with hypertension (high blood pressure), hibiscus tea can help, as it is known to lower blood pressure. You can also pick one of these herbal teas: chrysanthemum tea, flax tea, periwinkle tea, red root tea, self-heal tea, white peony root tea, valerian tea, or wild cherry bark tea. You can also drink hyssop tea, barberry tea, and rosemary tea, regardless of the blood pressure problem. These three teas will help regulate your blood pressure and reduce the risk of getting either high or low blood pressure problems. Tea for low blood pressure In the case of hypotension (low blood pressure), some of the teas you can try include lovage tea, ephedra tea, wu yi tea, cat’s claw tea, vervain tea, or wheatgrass tea. Black tea can help too, though you have to be careful with it as it has a high content of caffeine. Forbidden teas for blood pressure problems There are several teas which you should avoid drinking, no matter if you’ve got problems with high blood pressure or low blood pressure. The list of teas you shouldn’t drink includes arnica tea, black cohosh tea, gentian tea, juniper tea, lobelia tea, red ginseng tea, sage tea, stone root tea, and yohimbe tea. Also, generally it isn’t recommended to drink tea that lowers blood pressure if you’ve got hypotension, or tea that leads to high blood pressure if you’ve got hypertension. Whether you’ve got problems with high blood pressure or low blood pressure, try a more natural treatment: choose one of the many teas for blood pressure!... tea for blood pressure

Xanthelasma Palpebrarum

These yellow smooth nodules of LIPID-laden cells occur in and around the eyelids (see EYE). Blood lipids are usually normal, but there is an association with hypercholesterolaemia (see CHOLESTEROL; HYPERLIPIDAEMIA) in a minority of sufferers.... xanthelasma palpebrarum

Xenotrans Plantation

TRANSPLANTATION of organs from one species to another – for example, from pigs to humans. The use of organs from appropriately cloned animals was seen as a possible solution to the shortage of human organs for transplantation; however, research has shown that rejection remains a problem and there is also an unresolved possibility that diseases might be transmitted across the species barrier. It seems likely that STEM CELL research will provide a more realistic source of tissues for transplantation to replace diseased organs in humans.... xenotrans plantation

Tea For Kidney Problems

If you’re experiencing abdominal pain and you’re sure it’s not a digestive tract ailment, it’s very possible that you’re suffering from a kidney disorder. The same if the pain is localized in the back or on one side of your body. Usually, kidney problems appear when there’s something wrong with your urinary tract and not only. Overexposing your body to low temperatures may cause urinary infections, impurity accumulations lead to kidney stones. Also, kidney problems can be caused by other health complaints, such as pulmonary edema and cancers. However, it’s best to schedule an appointment with your doctor in order to find out what’s actually going on with your body. How a Tea for Kidney Problems Works A Tea for Kidney Problems’ main goal is to purify your body by triggering a positive response from it. Once the main substances of these teas reach the affected areas, your organism produces enough endorphins (which are cells specialized in making you feel a lot better by bringing relief to your wounds) and antibodies to reconstruct the damaged tissue. Efficient Tea for Kidney Problems In order to work properly, a Tea for Kidney Problems needs to be both efficient and one hundred percent safe. Also, it must contain the right amount of nutrients, natural enzymes, volatile oils, antioxidants and minerals (sodium, magnesium, iron and manganese). This way, that tea will make your body eliminate the unwanted impurities and improve your kidney function. If you don’t know which teas would be appropriate for your condition, here’s a list to choose from: - Dandelion Tea – can be prepared from dandelion roots and it’s also a great adjuvant in diarrhea and urinary infection cases. This Tea for Kidney Problems has a bitter taste, but you can add ginger, lemon, mint or honey in order to make it more adequate for you. Avoid it at all costs if you’re pregnant or breastfeeding: due to its strong purgative and diuretic properties, Dandelion Tea can cause uterine contractions which may lead to miscarriages. - Marshmallow Root Tea – this lovely tea with a hint of Christmas is useful for a large variety of problems, from infertility to gastrointestinal and digestive complaints. Take a sip at every 5 minutes for an hour and enjoy the wonderful health benefits! - Buchu Tea – contains antioxidants and antibacterial agents, being a great help in cases of cystitis, urethritis and kidney failure. This Tea for Kidney acts like a natural diuretic and should not be taken by pregnant women. - Green Tea – as the scientists have proved, this decoction contains all the ingredients necessary to sustain life, so it’s useful for many problems, not just kidney disorders. However, don’t take it if you’re experiencing menstrual and menopausal symptoms (it can cause uterine contractions and stomach acidity). Tea for Kidney Problems Side Effects When taken properly, these teas are generally safe. However, exceeding the number of cups recommended per day might lead to a number of health problems such as miscarriages, hallucinations, headaches and skin rash. If you’ve been taking one of these teas and something doesn’t feel quite right, talk to your doctor as soon as possible. Don’t take a Tea for Kidney Problems if you’re pregnant, breastfeeding, on blood thinners or anticoagulants. The same advice if you’re preparing for a surgery. If you have the medical approval and there’s nothing that could interfere with your treatment, choose a Tea for Kidney problems that fits best your needs and give it a try today!  ... tea for kidney problems

Tea For Psoriasis

Psoriasis is a chronic disorder in which skin cells grow abnormally fast. They need three to six days to mature while normal cells live for a month. The result is noticed because of: patches of dry, inflamed, white, scaly lesions on the scalp, hands, feet, knees and elbows. At the moment, there is no treatment against psoriasis. The existing medicinal remedies only alleviate symptoms. How Tea for Psoriasis works Teas for Psoriasis calm the abovementioned symptoms. Efficient Teas for Psoriasis It has been proved thatYellow Dock and Ginger tea are good as teas for psoriasis. Yellow dock is a perennial flowering herb, growing in Europe, parts of Africa and in the United States. The shape of the leaves gives the yellow dock its nickname: curled dock. The leaves, the roots and the submerged parts are used therapeutically. To prepare Yellow Dock tea, infuse about 10 grams (about 2 teaspoons) of yellow dock root in a cup of hot water for about 10 minutes.  It can be drunk three times a day. Ginger comes from the same family as marjoram and turmeric and it originates from Southeast Asia, today being extensively cultivated in Jamaica and other tropical areas. Its rhizome is used for culinary and medicinal purposes. To prepare Ginger tea, add 2 tablespoons of sliced roots to a cup of hot water. Steep the mixture for 15 minutes, strain it and drink it. Also, the tea may be applied topically. Tea for Psoriasis: Side effects Yellow dock can induce diarrhea. Also, both teas for psoriasis should not be taken while pregnancy or breastfeeding. It is important to know that a cure for psoriasis has not been discovered yet. Still, teas for psoriasis help in alleviating the symptoms of this skin disorder and the results are different from patient to patient.... tea for psoriasis

Yellow Evening Primrose

Hunting... yellow evening primrose

Active Principle

There are active and passive (in-active) constituents in all plants. An active principle is the most active constituent.

The amount of active constituent of a plant is not constant. The percentage of active constituent varies greatly. For this reason official pharmacy standardises drugs. See: WHOLE PLANT. ... active principle

Anti-parasitics

Another term for ANTHELMINTICS.

ANTI-PERIODICS. Remedies that prevent the return of a disease that tends to recur (malaria). Peruvian bark, Ash Tree (Fraxinus excelsior). ... anti-parasitics

Anti-perspirants

Herbs that reduce sweating; anti-hidrotics.

Internal: White Willow bark, Red Sage.

External: Essential oils of Sage, Pine, Rosemary, Lavender. Blended with fresh lemon juice are marketed as a gentle spray without aerosol (Weleda). Zinc and Castor oil cream or ointment.

Bath preparations made from these oils; herbal soaps, massage oils. ... anti-perspirants

Tea For Lucid Dreams

Having a lucid dream means dreaming while being aware of the fact that you are dreaming. However, many people become lucid in the middle of the dream or, on the contrary, fall lose reality contact after being lucid at first. Although traditional medicine can’t be very helpful in these cases, alternative medicine has a few tricks up its sleeve. How a Tea for Lucid Dreams Works A Tea for Lucid Dreams’ main purpose is to make you recall what you have dreamed by calming your nervous system and improving your memory function. These teas are good for a number of other diseases, such as memory loss, headaches or migraines. However, talk to an herbalist or to your doctor before starting any kind of herbal treatment in order to make sure everything will be alright. Efficient Tea for Lucid Dreams In order to work properly, a Tea for Lucid Dreams needs to be both very efficient and one hundred percent safe (since lucid dreams are not exactly a medical problem, you may want to avoid developing one). A tea that is rich in antioxidants, nutrients, tannins, volatile oils and minerals (sodium, magnesium, iron, manganese) would be very adequate. You may want to avoid teas with a large amount of acid agents (they could cause stomach pain). If you don’t know which teas could be useful for lucid dreams, here’s a list for guidance: - Green Tea – contains all the ingredients necessary to sustain life, so it’s useful for a wide range of ailments, not just lucid dreams. If you’re suffering from infertility, anemia, asthenia, loss of appetite, digestive tract complaints or nervous system failure, this decoction could also be useful. However, you must avoid it at all costs if you’re experiencing some menstrual or menopausal symptoms. The same advice if you’re pregnant (it may cause uterine contractions and therefore miscarriage). - Valerian Tea – was been used as a sleep aid since ancient times, when the Romans and the Greeks took it before going to bed. This Tea for Lucid Dreams, thanks to its active compounds, is a mild sedative and could also work miracles on your nervous system. However, you need to make sure that you don’t exceed the number of cups recommended per day in order to avoid hallucinations, tiredness or even death. - Chamomile Tea – of course, the world’s greatest panacea shouldn’t be left aside. If you’re having trouble remembering your dreams, try a cup of Chamomile Tea before you go to bed! This Tea has a great fragrance and a pleasant smell. Plus, it’s one hundred percent safe so you can drink as much as you want. Tea for Lucid Dreams Side Effects When taken according to specifications, these teas are generally safe. However, exceeding the number of cups recommended per day may lead to a number of health problems, such as diarrhea, nausea, vomiting, upset stomach or even death! If you’ve been taking one of these decoctions for a while and you’re experience a negative response from your body, ask for medical assistance right away! Don’t take a Tea for Lucid Dreams if you’re pregnant, breastfeeding, on blood thinners or anticoagulants. The same advice in case you’re preparing for a surgery. If your doctor says it’s ok to start an herbal treatment, choose a tea that fits best your requirements and enjoy its wonderful benefits!  ... tea for lucid dreams

Terminalia Paniculata

Roth.

Family: Combretaceae.

Habitat: Forests of Western Ghats and Eastern Ghats up to 1,200 m.

English: Flowering Murdah.

Folk: Kinjal (Maharashtra); Neemeeri, Nimiri (Andhra Pradesh); Pekadukkai (Tamil Nadu); Pilamuruthu, Pillamurda (Kerala). Kindal (trade).

Action: Bark—diuretic, cardiotonic. Juice of the bark, mixed with purified butter and rock-salt, is applied in parotitis.

The heartwood gave 3,3'-O-di- methylellagic acid and 3,4,3'-O-tri- methylflavellagic acid. A triterpene carboxylic acid, beta-sitosterol, a gly- coside 3,3'-di-O-methylellagic acid- 4-monoglucoside and O-pentamethyl flavellagic acid have been isolated.

The bark contains 14% tannins, also beta-sitosterol.... terminalia paniculata

Thespesia Populnea

Soland. ex Correa.

Synonym: Hibiscus populneus Linn.

Family: Malvaceae.

Habitat: Coastal regions of India and the Andamans; and also grown as an ornamental.

English: Portia tree, Tulip tree, Umbrella tree, False Rosewood.

Ayurvedic: Paarisha, Kapitana, Paarshvpippala, Gardabhaanda.

Siddha: Poovarsu.

Action: Specific for skin diseases. Root, fruit and leaf—used in psoriasis, scabies and other cutaneous diseases. Lupenone, lupeol and alkanes show activity against both Gram-positive and Gram-negative bacteria. Bark— used for the treatment of haemorrhoids and chronic dysentery. Leaf— anti-inflammatory.

The flowers gave populnetin, herba- cetin, populneol, quercetin and its gly- cosides, kaempferol and its glycosides, rutin, gossypol, beta-sitosterol and its glycosides, nonacosane, lupenone, myricyl alcohol, lupeol and gossypetin.

Presence of thespesin (0.4%) and herbacetin has been reported from fruits. Thespesin has been proved to be optically active gossypol. Gossypol occurring in cotton plant is optically inactive, whereas the gossypol from T. populnea has a high dextro-rotation. It exhibits antifertility, anti-tumour, anti-amoebic and anti-HIV activities.

The ethanolic extract of fruits showed antiviral and anticancer activity in mice.

Dosage: Root—50-125 mg powder. (CCRAS.)... thespesia populnea

Anti-protozoals

Remedies that inhibit the action of protozoa, a class of single-celled microscopic animals. Ipecacuanha, Peruvian bark. ... anti-protozoals

Anti-pruritics

Agents to relieve intense itching. Chamomile, Chickweed, Clivers, Cucumber, Goldenseal, Marigold, Sarsaparilla, Peppermint, St John’s Wort. ... anti-pruritics

Anti-pyretic

Another term for FEBRIFUGE. ... anti-pyretic

Tea For Pink Eye

Pink Eye or Viral Conjunctivitis is commonly associated with other upper respiratory tract ailments, such as flu, cold or sore throat. At times, this affection is consistent with tearing and itching or it can be a congenital problem in which case you need to talk to your doctor about it, in order to stop it from developing in time. Having a pink eye can also be caused by a series of heart problems: in cases of heart attacks or strokes, the blood veins sometimes erupts in the eye area. How a Tea for Pink Eye Works A Tea for Pink Eye’s main purpose is to make sure that your body produces enough antibodies to treat the affected area and stop this infection from developing again. The best Tea for a Pink Eye must contain a high amount of nutrients, natural enzymes, volatile oils and be very low on acids. When taking a cure to treat this affection, remember this is a medical remedy and must be taken according to specifications. If you’re not sure about a certain decoction, ask a specialist in order to gather more information. Efficient Tea for Pink Eye When choosing a Tea for Pink Eye, you must keep in mind the fact that it must be both very efficient and one hundred percent safe. Pink eye is not a very serious condition and you can only treat it if you also treat the problem that triggered it in the first place. Since this is not an important health problem, it’s best to try an herbal remedy before rushing on to the drug store. If you don’t know which teas are best for you, here’s a list to help you out: - Green Tea – this wonderful herbal treatment must be in all medicine cabinets in the world! Its active constituents can cleanse your entire body and energize your system. However, always make sure that you’re following the instructions. Don’t take it if you’re experiencing menstrual or menopausal pains in order to avoid uterine and abdominal contractions. - Ginkgo Biloba Tea – used for a number of other affections, this Tea for Pink Eye will improve your circulation, your respiratory system health, which will make your eye get back to normal. Just make sure you don’t drink more than 2 cups per day in order to avoid other complications like diarrhea or upset stomach. - Chamomile Tea – of course, you must never forget the world’s greatest panacea! It’s also good for digestive, respiratory and circulatory problems and it will nourish your nervous system in no time! This tea for Pink Eye is one hundred percent safe so you can drink as much as you want. Tea for Pink Eye Side Effects When taken properly, these teas are generally safe and have no side effects at all. However, exceeding the number of cups recommended per day might lead to nausea or vomiting. Before starting a treatment based on herbs, ask your doctor about the risks and make sure there’s nothing that could interfere with your treatment. Once you have the medical approval, choose a tea that fits best your needs and enjoy its health benefits!... tea for pink eye

Thevetia Peruviana

(Pers.) K. Schum.

T. neriifolia Juss. ex

Family: Apocynaceae.

Habitat: Native to tropical America; cultivated as hedge plant in the plains throughout India.

English: Yellow Oleander.

Ayurvedic: Pita-Karavira, Ash- vaghna, Divyapushpa. (White and red-flowered var. is equated with Nerium oleander, the yellow- flowered var with T. peruviana.)

Siddha/Tamil: Pachiyalari.

Action: See Nerium oleander. Bark and leaves—bitter cathartic, emetic; poisonous. Roots—a plaster is applied to tumours.

All parts of the plant produce poisonous latex. Karnels contained nearly seven times as much glycosides as leaves, stems, flowers or fruit pulp. The roots and bark also contain glycosides.

Of all Thevetia glycosides, peruvo- side is the most important cardiac gly- coside. It produced a fall in right arterial pressure and a rise in cardiac output. A few cases of arrhythmia responded well to peruvoside. Thevetin and other glycosides are reported to exhibit digitalis-like effect. As a cardiac glyco- side, the potency of neriifolin is moderate. Cerberin is even weaker than neriifolin. Cerebroside is the weakest glycoside in its cardiac effect.

In addition to seeds, neriifolin and peruvoside have been isolated from the bark in small amounts.... thevetia peruviana

Beecham’s Pills

Ingredients: Aloes 42mg; Anise oil 200 micrograms; Capsicum oleoresin 100 micrograms (mcg); Ginger oleoresin 400mcg; Juniper oil 700mcg; light magnesium carbonate 2-5mg; Soap (hard) 9.7mg; Rosemary oil 700mcg; Ginger 20.3mcg; Coriander 4.4mg. (Beecham Proprietaries) ... beecham’s pills

Belaiche, Dr Paul

Chairman, Department of Phyto-therapy, Faculty of Medicine, Bobigny, University of Paris. European authority on use of essential oils (Aromatherapy) in medicine. Commended for his work on Tea Tree oil. ... belaiche, dr paul

Box’s Indigestion Pills

Ingredients: Myrrh 18.2 per cent. Gentian 18.2 per cent. Ginger 18.2 per cent. Aloes 18.92 per cent. Capsicum 18.2 per cent. Acacia 6.3 per cent. Cajuput oil 2.7 per cent. For dyspepsia. Very popular in their day but now obsolete. ... box’s indigestion pills

British Herbal Pharmacopoeia

World-accepted work. New edition published: 1990, fully revised and updated. Over 80 monographs. Official publication of the British Herbal Medicine Association to set and maintain standards of herbal medicine. Does not contain Therapeutic Section and index that appear in the 1983 edition, but describes macroscopical and microscopical characteristics. Quantitative standards, methods of identification, commercial form and source and description of the powdered form. BHP 1990 vol 1 is available from BHMA Publications, PO Box 304, Bournemouth, Dorset, England BH7 6JZ (£35). Abbreviation: BHP. ... british herbal pharmacopoeia

British Journal Of Phytotherapy

Published six-monthly by the School of Phytotherapy (Herbal Medicine), edited by Hein Zeylstra. Scientific journal for the professional. Enquiries: School of Phytotherapy, Bucksteep Manor, Bodle Street Green, near Hailsham, East Sussex BN27 4RJ, UK. ... british journal of phytotherapy

Teas For Menstrual Pain

Menstrual pain is known for its acute and localized action on the abdominal area. However, not all women suffer from this affection.The good thing about menstrual pain, however, is that this is not a chronic disease and that it can go away as quickly as it came to you. All you have to do is treat it properly and wait for your body to respond. If the pain is very powerful and you need to put a stop to it, you may want to try taking an herbal treatment, in which case Raspberry leaf tea, Corn silk tea and Wild yam tea could be the answer. How Teas for Menstrual Pain Work Most of these Teas for Menstrual Pain involve helping your body release the right amount of endorphins in order to fight localized pain. Although menstrual pain is probably the most popular cause of distress for women around the world, alternative medicine found new ways to fight it alongside with traditional medicine. However, choosing one of these Teas for Menstrual Pain will only make your system healthier, without having to worry for possible side effects. The main characteristic of these Teas for Menstrual Pains is that they have a pleasant taste and fragrance and that they are generally safe, unlike traditional medicines. A cup of raspberry leaf tea brings relief to your abdominal area, by calming the muscles and increasing the uterus action. Efficient Teas for Menstrual Pain If you have a heavy menstrual flow or a severe pain crisis during periods, you may find out that the following Teas for Menstrual Pain could be the right answer to your problems: - Cramp Bark Tea – thanks to its antispasmodic and anti-inflammatory properties, Cramp Bark Tea is one of the best Teas for Menstrual Pain there is! Unfortunately, it’s rather inaccessible to the European public. However, if you find a shop that specializes in Cramp Bark products, hold on to it! Cramp Bark Tea can also be used as a detoxifier and a good face cleanser; when used topically, it may bring relief to your skin sores. - Raspberry Leaf Tea – this is a tea that may also come in hand in case you want to perform natural cosmetic procedures at home. Just soak a compress in Raspberry Leaf Tea and apply it on your face for 5 minutes to open and clean your pores. However, a cup of Raspberry Tea per day will improve your general health, bringing relief to those of you who are suffering from severe menstrual pain. - Corn Silk Tea – on this Teas for Menstrual Pain list, Corn silk Tea use needs extra caution. It is true that it can calm your menstrual pain, but you also need to measure the amount of tea you drink in order to avoid other complications: Corn Silk Tea is a very powerful urinary stimulant. - Wild Yam Tea – one of the most dangerous Teas for Menstrual Pain, Wild Yam Tea can bring relief to all kinds of pain, starting with menstrual pain, stomach pain and ending with migraines and severe headaches. However, don’t take this tea if you have protein S deficiency or a hormone-sensitive condition, such as breast cancer, uterine fibroids or endometriosis. Teas you should avoid During menstruation, you may want to avoid all teas based on a high level of acids, such as green or black teas . They will only make your pain insufferable, by increasing your stomach acidity and also your heart beat. Teas for Menstrual Pain Side Effects When taken according to specifications, these Teas for Menstrual Pain are rarely dangerous. However, if you’ve been taking one of them for a while and you’re experiencing some unusual reactions from your body, talk to a doctor as soon as possible. In high dosages, these teas may cause urinary dysfunctions, nausea, headaches and vomiting. First, make sure you’re not allergic to the tea you’re about to take in order to avoid other health complications. Once you have the green light from your doctor, give these Teas for Menstrual Pain a try and enjoy their wonderful benefits wisely!... teas for menstrual pain

Tragopogon Porrifolius

Linn.

Synonym: T. sinuatum Ave. Lall.

Family: Compositae; Asteraceae.

Habitat: Native to Europe; grown in Himachal Pradesh and Maharashtra.

English: Salify, Vegetable-Oyster, Purple Goat's Beard, Oyster Plant.

Action: Root—specific in obstructions of the gall in jaundice; antibilious. Also used for treating arteriosclerosis and high blood pressure.

T. porrifolius contain several flavo- noids, including orientin and iso- orientin.

The seeds yield an oil which contains a saturated epoxy acid viz. cis-9, 10-epoxysteric acid and several conjugated dienoic acids.

Cooked flashy roots of T. porrifolius contain sodium 8, potassium 183, calcium 60, magnesium 14, iron 1.2, copper 0.1, phosphorus 53, sulphur 25 and chlorine 46 mg/100 g. A large parts of carbohydrates occur as inulin.... tragopogon porrifolius

British Pharmacopoeia, The

Provides authoritative standards for the quality of many substances, preparations and articles used in medicine and pharmacy, and includes the monographs of the European Pharmacopoeias. A legally enforceable document throughout the UK, most of the Commonwealth and many other countries, and is an indispensable laboratory handbook for all concerned with the quality of medicines. Published on the recommendation of the Medicines Commission pursuant to the Medicines Act 1968. Published by Her Majesty’s Stationery Office, London. The most useful BPC for the herbal practitioner is the BPC 1934. ... british pharmacopoeia, the

Catechu, Pale

 Gambier. Uncaria gambier Roxb. Shoots. Leaves. Constituents: flavonoids, tannins, indole alkaloids.

Action: Intestinal astringent.

Uses: similar to Black Catechu.

Preparations: Twice daily.

Powder: 0.3 to 1 gram (quarter of a teaspoon) in honey or banana mash.

Tincture Catechu BP. 1:5, with Cinnamon 1:20, in 45 per cent alcohol. Dose: 2.5 to 5ml. ... catechu, pale

Cow Parsley, Himalayan

Heracleum brunonis benth, (umbellifera). Contains coumarins. Related to Angelica.

Action. Photosensitiser, antifungal, tuberculostatic. (Journal of Natural Products 1987, 50(5), pp997-8) Uses. Leucoderma. Vitiligo. Reputed fading of coloured areas of skin. ... cow parsley, himalayan

Curry Powder

Madras Special. Parts: Coriander 13; Black Pepper 5; Cayenne 1; Cumin 6; Fenugreek 6; Turmeric 6. Mix. Grind. Sift. Store in airtight jar. A rich source of copper. ... curry powder

Tephrosia Purpurea

(L.) Pers.

Synonym: T. hamiltonii Drumm.

Family: Papilionaceae; Fabaceae.

Habitat: All over India; also grown as green manure and as cover crop.

English: Purple Tephrosia, Wild Indigo.

Ayurvedic: Sharapunkhaa, Vishikha-punkhaa, Sarphokaa.

Unani: Sarponkhaa, Sarphukaa.

Siddha/Tamil: Kattu-kolingi, Kolingi, Paavali, Mollukkay, Kollukkayvelai.

Action: The drug is considered specific for the treatment of inflammation of spleen and liver (is known as Plihaa-shatru, Plihaari in Indian medicine).

Dried herb—diuretic, deobstruent, laxative. Given for the treatment of cough, bronchitis, bilious febrile attacks, insufficiency of the liver, jaundice (not effective in infantile cirrhosis), kidney disorders and for the treatment of bleeding piles, boils, pimples. Also used as a gargle. Root—decoction used in dyspepsia, diarrhoea, cough, bronchitis, adenoids, asthma and rheumatism. Juice is applied to skin eruptions. A liniment prepared from the root is employed in elephantiasis. Oil from seeds—specific against eruptions of the skin, eczema, scabies, leprosy. Seed extract—hypoglycaemic.

Powdered aerial parts prevented elevation of SGOP, SGPT and bilirubin levels.

Hepatoprotective effect of aerial parts was evaluated against (+)-galac- tosamine-induced and carbon tetra- chloride-induced hepatotoxicity in rats.

The leaves contain rutin and rote- noids (0.65-0.80% on dry basis). Rote- noid content is highest in the seed (1.60-1.80%).

The leaves also contain a triterpe- noid, lupeol, and beta-sitosterol.

Seeds contain a diketone-pongamol; a dimethylchromene flavanone iso- lonchocarpin; furanoflavones karan- jin and kanjone; a flavanone purpurin; and sitosterol. A flavonoid, lanceolarin B, is also present in seeds.

The plant extract led to marked lowering of blood glucose level in normal and alloxan-induced diabetic rabbits. In diabetic rabbits the extract exerted 60-70% hypoglycaemic effect as compared to tolbutamide.

Shveta Sharapunkhaa (stems: covered with white hair; flowers: pale pink or pale violet) is equated with T. villosa Pers.

The roots gave a prenylated fla- vanone 7-methylglabranin; pods contain rotenoids—villosin, villon, vil- losol, villosinol, villinol and villosone.

The fresh root is credited with hy- poglycaemic properties, but leaves did not show any such effect. The juice of the leaf is given in dropsy. Ayurve- dic classical texts describe it as a special drug for treating sterility in women.

Boiled leaves of T. uniflora subspecies petrosa (Kant-punkhaa) are used for the treatment of syphilis. The medicinal properties of the plant are more or less similar to those of T. purpurea, but to a milder degree.

T. spinosa Pers. (South India, ascending to 400 m in hills) is also known as Kant-punkhaa (Mulukolingi in Tamil Nadu).

The root is applied to inflammations and swellings of joints; a decoction is given in rheumatism.

Chalcones, spinochalones A and B and flemistrictin A have been isolated from the root. Spinochalone C and spinoflavonones A and B, and fulvin- ervin A have been isolated from the plant.

Dosage: Plant, root, seed—3-5 g powder. (CCRAS.)... tephrosia purpurea

Trianthema Portulacastrum

Linn.

Family: Aizoaceae.

Habitat: South India, Gujarat, Rajasthan, Uttar Pradesh and Haryana.

Ayurvedic: Varshaabhu (related species).

Siddha/Tamil: Vellai Sharunnai.

Folk: Bisakhaparaa.

Action: Root—deobstruent; used for asthma, hepatitis and amenorrhoea. The root, leaf and stem gave positive test for alkaloid. The plant is a good source of zinc (1.077 ± 0.188) and copper (0.416 ± 0.057) mg/100 g.

Synonym: T. monogyna Linn.

Family: Aizoaceae.

Habitat: Cultivated fields and wastelands.

English: Horse Purslane.

Ayurvedic: Varshaabhu, Vrshchira, Vishakharparikaa, Shilaatikaa, Shothaghni, Kshdra. Wrongly equated with Shveta-punarnavaa or Rakta-punarnavaa. Varshaabhu and Punarnavaa are two different herbs. T. portulacastrum is a rainy season annual. Rakta-punarnavaa is equated with Boerhavia diffusa, Shveta-punarnavaa with white- flowered species, B. erecta L. (B. punarnava).

Unani: Biskhaparaa.

Siddha: Sharunai.

Folk: Pathari, Bisakhaparaa.

Action: Root—antipyretic, analgesic, spasmolytic, deobstruent, cathartic, anti-inflammatory.

Leaves—diuretic; used in oedema and dropsy. A decoction of the herb is used as an antidote to alcoholic poison.

The Ayurvedic Pharmacopoeia ofIn- dia recommends the dried root in diseases of the liver and spleen, anaemia and oedema.

Ethanolic extract of the aerial parts exhibited hepatoprotective activity in CCl4-induced intoxication in rats. The acetone-insoluble fraction of the extract is responsible for the activity.

The red and white flowers contain an alkaloid trianthemine, also punaranavine. The plant also gave ecdysterone (0.01 g/kg), a potential chemosterilant; nicotinic acid and ascorbic acid. The plant is rich in phosphorus and iron but poor in calcium.

The high content of oxalate affects the assimilation of calcium. Carotene (2.3 mg/100 g) has also been reported.

Trianthema sp. are used as adulterant of the roots of Boerhavia diffusa.

Dosage: Root—2-5 g powder. (API, Vol. IV.)... trianthema portulacastrum

Dental Problems

See: TEETH DECAY, TEETH EXTRACTION, ALOE VERA. DEOBSTRUENT. That which clears obstruction by dilating natural passages of the body. Usually of the intestines (Ispaghula seeds) or colon (Buckbean). ... dental problems

Dermatitis, Pseudomonas

 Itchy rash contracted in swimming pools, sports clubs or public baths caused by pseudomonas aeruginosa. Runs a self-limiting course from 7-14 days. Garlic and Echinacea specific. ... dermatitis, pseudomonas

Thyme Tea Treats Menstrual Pains

Thyme Tea has been used since the old times to cure respiratory problems thanks to a very important volatile oil called thymol that acts as an antiseptic. Thyme is a perennial edible herb with small green leaves and lavender purple flowers. The best thing about it is that can be harvested all year round, even if in the winter the roots are frozen and dried and you need to pay more attention. Thyme is usually pest free, but if you’re thinking about growing it in your backyard, watch out for greenfly. Thyme Tea Properties Thyme Tea is usually added in cures concerning coughs, cold or fever episodes, not to mention its anti-fungal properties. Thanks to this particular quality, Thyme Tea is used to treat athlete’s foot and other skin conditions. The main ingredient of this tea is thymol, which has been discovered recently. However, people used to drink Thyme Tea for ages thanks to its curative properties. Thyme Tea Benefits The benefits of Thyme Tea are many, starting with its wonderful help concerning chest and respiratory problems, sore throat or even flatulence. Also, Thyme Tea it’s a great remedy for menstrual pains and premenstrual symptoms as well. The thymol found in this tea is used by the great medical companies to produce mouthwashes to treat gums infections and any other respiratory track inflammation. Thyme Tea had expectorant properties and it’s prescribed by many doctors as an adjuvant in clearing lung mucus. And let’s not forget the wonderful benefits that Thyme Tea offers when treating some of the digestive track problems such as excessive flatulence, nausea, indigestion, colic and loss of appetite. Aside from that, you can apply Thyme leaves on your cuts and opened wounds in order to disinfect and calm the affected area. How to make Thyme Tea Preparing Thyme Tea is easy. If you want to make 2 cups of tea, you need 2 cups of boiling water and 2 teaspoons of Thyme leaves. First, finely chop the herbs and pour the boiling water over it. Let it steep for about 10 or 15 minutes, depending on how concentrated you want it to be. You can drink it hot or keep it in your refrigerator and drink it cold whenever you want. However, don’t let the herbs boil too much: boiled plants lose their curative properties and you’ll not be able to try Thyme Tea’s wonderful benefits. Thyme Tea Side Effects According to many herbalists, drinking too much Thyme Tea can cause allergic reactions in your body or even increase its toxicity level. Also, if you are allergic to rosemary, basil, catmint, hyssop, oregano and celery, you’ll also be allergic to this tea. The best thing you can do is talk to your doctor before starting a treatment based on Thyme Tea. If you don’t know which aliments and teas cause you allergic reactions, see a specialist before taking any type of herbal treatment. Thyme Tea Contraindications Do not take Thyme Tea if you are pregnant or breastfeeding. Also, if you are experiencing vomiting episodes, it is best to talk to your doctor before making any move. Since Thyme Tea causes a highly expectorant reaction, it is indicated to drink a small quantity of it in order to avoid ulcers and other gastric problems. Drinking Thyme Tea usually causes no problem if you don’t drink more than 2 cups per day. So, if you have a sore throat and you are willing to try a natural remedy, Thyme Tea can be the right answer. Just pay attention to our indications and enjoy the wonderful benefits of this tea!... thyme tea treats menstrual pains

Tridax Procumbens

Linn.

Family: Asteraceae; Compositae.

Habitat: Waste places, road sides and hedges throughout India.

English: Mexican Daisy.

Ayurvedic: Jayanti (doubtful synonym).

Siddha/Tamil: Vettukkaaya-thalai.

Folk: Akala Kohadi (Bihar).

Action: Leaves—styptic, antidiar- rhoeal, antidysenteric. Also used for bronchial catarrh.

The leaf juice exhibits antiseptic, insecticidal and parasiticidal properties. It is used to check haemorrhage from wounds, cuts and bruises, also for restoring hair growth.

An aqueous extract of the plant produced reflex tachycardia and showed a transient hypotensive effect on normal blood pressure of dogs; it had also showed a marked depressant action on the respiration.

Alcoholic extract of the whole plant (excluding roots) at a dose of 300 mg showed good anti-secretory antidiar- rhoeal activity against E. coli enterotox- in-induced secretory response in rabbit and guinea-pig ileal loop models. Alcoholic extract of aerial parts also showed hepatoprotective action against acute hepatitis induced by CCl4 in albino rats.

The leaves contain fumaric acid. The plant gave n-alkanes, saturated and unsaturated fatty acids along with dotria- contanol, beta-amyrin, beta-amyrone, lupeol, fucosterol and beta-sitosterol. Flowers contain glucoluteolin, iso- quercetin and quercetin. Presence of lauric, myristic, palmitic, stearic, arachidic, behenic, palmitoleic, linole- ic and linolenic acid is reported in aerial parts except flower tops. cine, is used as Ispast. The seeds contain xanthosin.... tridax procumbens

Diet - Low Protein

Reduce intake of foods, taking small helpings: meat, eggs, poultry, fish, milk, cheese, dried peas and beans, pulses, nuts, bread, pasta, wheat flour.

Accept: rice, cornflour, honey, salad vegetables, all fruits, preserves. ... diet - low protein

Diet - Thin People

Often more difficult to ‘put on’ than to ‘take off’ weight. Eat plenty of carbohydrates: bread and wholemeal products. Butter, margarine and other fats, meats, eggs, cream and cheese. In order to metabolise these effectively, without kidney or liver congestion, large quantities of fresh fruits and vegetables and juices should be eaten. Increase daily Vitamin B-complex intake. See: THIN PEOPLE. ... diet - thin people

Ebers Papyrus

The first medical records of Ancient Egypt containing 876 substances, most of them herbal including Castor oil, Valerian, Dill, Senna leaves; and goat fat as a base for ointments. The papyrus, written about 1500 BC contains prescriptions and formulae covering wide range. Medicines still in use today: Myrrh, Wormwood, Peppermint, Anise, Fennel, Lotus flowers, Linseed, Juniper berries, Gentian, etc. ... ebers papyrus

Trifolium Pratense

Linn.

Family: Papilionaceae; Fabaceae.

Habitat: Kashmir to Garhwal at 1,200-2,400 m, and the Nilgiris.

English: Red Clover.

Unani: Ispast, Berseem, Clover (equated with T. alexandricum Linn.)

Folk: Trepatra (Punjab).

Action: Flower—deobstruent, antispasmodic, expectorant, sedative, anti-inflammatory, antidermatosis.

Used for psoriasis, eczema and other skin diseases; and as an expectorant in coughs and bronchitis. Also used as antineoplastic against tumours and hard swellings.

The plant contains iso-flavonoids— calycosin - 7 - galactoside, calycosin, pseudobaptigenin, fornononetin, di- adzein and medicagol; also hydroxy- pterocarpans.

The flowerheads contain phenolic glycosides, flavonoids, salicylates, coumarins, cyanogenic glycosides, starch and fatty acids. Flavonoids in the flowers and leaves are oestro- genic; provide relief in menopausal complaints.

The British Herbal Pharmacopoeia recognizes anti-inflammatory property of the flower.

Trifolium alexandricum, according to National Formulary of Unani MediMedicine, is used as Ispast. The seeds contain xanthosin.... trifolium pratense

Types Of Psychologist

EDUCATIONAL PSYCHOLOGISTS Working in schools and in local education authorities, they are concerned with children’s learning and development. They carry out tasks aimed at improving children’s learning and helping teachers to become more aware of social factors that affect teaching and learning. Chartered educational psychlogists have a graduate degree in psychology and also a teaching quali?cation, with experience; in addition they have completed a one-year postgraduate course in educational psychology with supervised experience. COUNSELLING PSYCHOLOGISTS apply psychology to working in collaboration with people across a range of human problems. For example, helping people to manage di?cult life events, relationship issues, BEREAVEMENT and issues raised by mental-health problems. Their usual route to qualify is completing a three-year postgraduate training in counselling psychotherapy. CLINICAL PSYCHOLOGISTS have completed a three-year doctorate training course as well as having their ?rst degree in psychology. They work in health and care settings. Their aim is to reduce psychological distress and to promote psychological well-being. They work with individuals, families, groups and organisations: the individuals are people who have problems such as anxiety, DEPRESSION, serious and enduring MENTAL ILLNESS, brain injuries, addiction, child and family problems, LEARNING DISABILITY and the after-effects of trauma. They provide various types of treatment, for example COGNITIVE BEHAVIOUR THERAPY and family therapy, based on psychological theories and research. They also carry out research, training, consultation with other professionals involved with clients, and supervision of colleagues.

(See also NEUROSIS; PSYCHOTHERAPY.) FORENSIC PSYCHOLOGISTS work in the

criminal and justice ?elds, applying psychological theory to aspects of legal processes in courts, criminal investigation, and understanding and treating psychological problems associated with criminal behaviour. They will have completed an accredited training course in forensic psychology. HEALTH PSYCHOLOGISTS apply psychological methods to studying behaviour relevant to health, illness and care including health promotion and education. OCCUPATIONAL PSYCHOLOGISTS are concerned with how people perform at work and how organisations function. They work in management, personnel, selection and careers advice. They have a postgraduate degee in occupational psychology and will have had to undertake three years’ supervised practice.... types of psychologist

Ejaculation, Premature

Emission of semen before sexual partner is prepared for orgasm. Agnus Castus, Vervain, Cramp bark, Mistletoe, Valerian. ... ejaculation, premature

Evans, William C. (b.pharm., B.sc., Ph.d., F.r. Pharm. S)

Formerly Reader in Phytochemistry, Department of Pharmacy, University of Nottingham. Research interests: secondary metabolites of the Solanaceae and Erythroxylaceae. Principal author of Trease and Evans’ Pharmacognosy. Visiting lecturer, School of Phytotherapy (Herbal Medicine). ... evans, william c. (b.pharm., b.sc., ph.d., f.r. pharm. s)

Eyes – Pain

A number of causes including reflex pain from inflammation of the middle ear or decayed teeth. Eyeball tender to touch.

Alternatives. Plantain, Ginkgo. Teas, tablets, etc.

Topical. Cold compress: Witch Hazel.

Supplements. Daily. Vitamins C (500mg); E (400iu). Beta-carotene. Palming. ... eyes – pain

Eyes – Pouches Under

Due to a number of causes including kidney disturbance.

Tea. Equal parts: Clivers, Wild Carrot, Yarrow. Mix. 1 heaped teaspoon to each cup boiling water; infuse 15 minutes. Half-1 cup 2-3 times daily.

Topical. Soak cotton wool pads with Witch Hazel Distilled Extract and place over the closed eyelids for ten minutes, once or more daily. ... eyes – pouches under

Uraria Picta

Desv.

Synonym: Hedysarum pictum Jacq.

Family: Papilionaceae; Fabaceae.

Habitat: Throughout India, in dry grasslands. Ayurvedic: Prishniparni, Prithak- parni, Simhapushpi, Kalashi, Dhaavani, Guhaa, Chitraparni.

Siddha/Tamil: Oripai.

Action: Root—prescribed for cough, chills and fevers. Leaves—antiseptic, used for urinary discharges and genitourinary infections.

The Ayurvedic Pharmacopoeia of India recommends a decoction of whole plant in alcoholism, insanity, psychosis; cough, bronchitis, dyspnoea; diseases due to vitiated blood; gout; bleeding piles; blood dysentery, acute diarrhoea.

The plant is credited with fracture- healing properties. Its total extract exhibits better and quicker healing of fractures in experimental animals due to early accumulation of phosphorus and more deposition of calcium.

Dosage: Whole plant—20-50 g powder for decoction. (API, Vol. IV.)... uraria picta

Urtica Pilulifera

Linn.

Habitat: Simla and other hill stations.

English: Roman Nettle.

Ayurvedic: Used as a substitute for Vrishchiyaa-shaaka.

Unani: Anjuraa.

Action: Diuretic, astringent, haemostatic.

The leaves and stems contain an indole alkaloid, bufotenin. 5-hydroxy- tryptamine is located mainly in strings.

Urtica urens Linn. (Dog Nettle, Small Nettle) is found in Dehra Dun and is Udhampur district of J. & K. The inflorescence and leaves contain the flavonoid compounds of kaempfer- ol, isorhamnetin, quercetin, apigenin, diosmetin and luteolin. Presence of chlorogenic acid is also reported.

The fluid extract of roots has been found to be useful in mild cases of prostate enlargement by improving micturia in men over 60 years.... urtica pilulifera

Vaccaria Pyramidata

(L.) Medik.

Synonym: Saponaria vaccaria L.

Family: Caryophyllaceae.

Habitat: Throughout India, as a weed.

English: Soapwort, Cow Herb.

Folk: Musna, Saabuni.

Action: Roots—used for cough, asthma and other respiratory disorders; for jaundice, liver and spleen diseases (increases bile flow). Mucilaginous sap—used in scabies.

Saponins of the root showed haemo- lytic activity. Lanostenol, stigmas- terol, beta-sitosterol and diosgenin have been isolated from the plant. Xanthones, vaccaxanthone and sapx- anthone, and a oligosaccharide, vac- carose, have also been isolated.... vaccaria pyramidata

Vandellia Pedunculata

Benth.

Synonym: Lindernia cordifolia (Colsmann) Merrill.

Family: Scrophulariaceae.

Habitat: The Himalayas up to 1,2001,700 m and throughout India.

Folk: Gadaga-vel (Maharashtra).

Action: Used for sexually transmitted diseases and urethral discharges.

Vandellia pyxidaria Maxim, synonym Vandellia erecta Benth. (The Himalayas from Kashmir to Assam, common in Bengal; also in central and South India) is known as Vakapush- pi. The plant is used for gonorrhoea. Plant juice is given to children who pass green stool.... vandellia pedunculata

Viburnum Prunifolium

Linn.

Habitat: Native to eastern and central USA. (Experimental cultivation in the Nilgiri hills.)

English: Black Haw.

Ayurvedic: Tilvaka (related species).

Action: Uterine sedative (used in the treatment for threatened miscarriage, under strict medical supervision. Spasmolytic. (The British Herbal Pharmacopoeia.) Used after childbirth to check bleeding and pain, also in dysmen- orrhoea.

The stem and root bark gave couma- rins including scopoletin, aesculetin and scoplin; a biflavone, amentofla- vone; triterpenes including oleanolic and ursolic acid and their acetates, caffeic acid derivatives; salicylic acid, salicin, arbutin (traces); tannins (2%).

Coumarin, scopoletin, is a uterine sedative, while salicin is an analgesic.... viburnum prunifolium

Father Pierre’s Monastery Herbs

Contain Frangula 2.5 per cent, Senna leaves 65.25 per cent, Ispaghula 6.75 per cent, Meadowsweet 5.125 per cent, Mate leaves 13.5 per cent, Nettles 6.75 per cent. Non-persistent constipation. ... father pierre’s monastery herbs

Fever Powder

No. 10. Equal parts: Lobelia herb, Pleurisy root, Crawley root, Catmint (Catnip), Sage. In powder form. Dose: One heaped teaspoon in cup; fill with boiling water; steep half an hour. 3-5 tablespoons every half hour while fever is on. Dose: small child, quarter of a teaspoon; child, half a teaspoon. For most kinds of fever it is a safe and efficient febrifuge. Never allow fever powder to be boiled. (Dr Melville Keith)

Widely used by the Eclectic School during second half of the 19th century. ... fever powder

Foot Powder

For foot-sweat and general discomfort. Mix into 1oz (30g) cornflour a few drops of any of the following oils, according to personal choice: Lavender, Geranium, Eucalyptus, Lemon, Pine. ... foot powder

Glentona Herbal Blood Purifier

Popular blood tonic of the 1930s, 1940s and 1950s. Ingredients: Liquid Extract Liquorice 5 per cent, Infusion Gentian Co Conc 10 per cent, Infusion Senna Conc 5 per cent. And 25 per cent alcoholic extractive from Burdock 5 per cent, Red Clover 5 per cent, Queen’s root 2.5 per cent, Yellow Dock root 1.25 per cent, Poke root 2.5 per cent, Sarsaparilla 2.5 per cent. (Carter Bros) ... glentona herbal blood purifier

Vinca Pusilla

Murr.

Synonym: Catharanthus pusillus G. Don.

Lochnera pusilla (Murr.) K. Schum.

Family: Apocynaceae.

Habitat: West Bengal and throughout greater part of India, as a weed.

Ayurvedic: Sangkhi, Sangkhaphuli (The Wealth of India).

Folk: Milagaipoondu (Tamil Nadu), Kapavila (Kerala), Vishakane- gale (Karnataka), Neru (Andhra Pradesh) Mirchaai (Bihar).

Action: Plant—oncolytic (tumour- resolving). A decoction of the dried plant boiled in oil is used in the treatment of lumbago.

The plant contains ajmalicine, rau- wolscine, vindoline, pusiline and pusi- linine, while leurosine, lochnerinine, venoterpine, vindorosine and vincapu- sine have been isolated from the leaves. The root gave lochnericine. Leurosine is cytotoxic. Pusiline and pusilinine cause marked depression of the heart.... vinca pusilla

Vitex Peduncularis

Wall. ex Schauer.

Family: Verbenaceae.

Habitat: Assam, West Bengal, Bihar and South India.

Ayurvedic: Kaakajanghaa. (Leea aequata Linn. is also equated with Kaakajanghaa.)

Folk: Chirai-godaa, Chirai-gorwaa, Naagpheni.

Action: Leaves and bark—used in malarial and black water fevers. Leaves—antibacterial.

The leaves and root bark gave pachy- podol, ursolic acid, vitexin and pedun- cularcin.... vitex peduncularis

White Peony Root Tea Benefits

White Peony Root Tea is one of the most important herbs in Asian medicine, being used since ancient times to treat liver problems and to improve women’s general health. White Peony Root Tea can be made from a plant called Chinese peony or common garden peony, a perennial herb that grows in Eastern China, southern Tibet and Siberia. You can recognize it after its big white flowers and yellow stamens. The leaves are deep green and medium sized. White Peony Root Properties The best thing about White Peony Root Tea is that its properties contribute to a better general health of the human body, thanks to a high concentration of acids and amino-acids and also to a great alkaline conductivity. The main ingredient in White Peony Root Tea is paeoniflorin, a substance that has a high anti-spastic action in many areas of your system. The other active substances that can be found in this tea and enhance the paeonflorin’s effect are flavonoids, proanthocyanidins, tannins and polysaccharides. White Peony Root Benefits White Peony Root Tea has anti-inflammatory, sedative, analgesic and diuretic properties. This tea is a great help if you suffer from one of the following conditions: - Liver malfunction, by energizing it thanks to its alkaline property and helping it flush away all the toxins. - Bad blood circulation or poor blood nourishment. Also, White Peony Tea can lower your blood pressure. - Menstrual problems that consist of heavy bleedings and aggravated abdominal pain, by calming the affected area and by bringing relief. - Abdominal and chest pains, dizziness, headaches. - Epilepsy, by stopping seizures and convulsions and by nourishing your nervous system, so that the negative reaction can be eliminated. How to make White Peony Root Tea Infusion Preparing White Peony Root Tea infusion is very easy. Use a teaspoon of White Peony Root for every cup of tea you want to make. Put the herbs in a teapot and add boiling water. Wait for 10 or 15 minutes (depending on the amount of water you’re using) and drink it hot or cold. Don’t take more than 3 cups per day. White Peony Root Tea Side Effects White Peony Root Tea is safe as long as you take it for a short amount of time. Taken in high dosages, it may cause rashes and problems of the nervous system. White Peony Root Tea is not to be taken unsupervised and it’s a medical treatment. Do not drink it as often as you drink your coffee! Also, a higher dosage will not make your general health improve any faster. Follow our recommendations and talk to a doctor before making any move. White Peony Root Tea Contraindications If you are pregnant or breastfeeding, you should not take White Peony Root Tea, because it may cause uterine contractions and blood clotting. But if you have the green light from your doctor, there’s no reason not to try White Peony Root Tea. Add it to your medicine cabinet, follow our instructions and enjoy the wonderful benefits of White Peony Root Tea responsibly!... white peony root tea benefits

Griping Pain

Acute pain in the abdominal cavity. Non-recurring.

Tea. Combine equal parts: Avens, Catmint, Thyme. 2 teaspoons to each cup boiling water; infuse 5 minutes. Half-1 cup freely.

Alternative: quarter of a teaspoon powdered Ginger, or Cinnamon in honey.

Enema: Catmint, Chamomile or Balm.

See: COLIC.

Persistent griping should be investigated. ... griping pain

Hamdard National Foundation, Pakistan

Greco-Arabian and Ayurvedic Medicine. Islamic Research and scholarship. Research into natural medicines on the Indian Continent and Far East; traditional medicines of Pakistan. President: Hakim Mohammed Said, distinguished physician, researcher and publisher.

Publications include: Hamdard Pharmacopoeia of Eastern Medicine; Greco-Arabian Concepts of Cardio-vascular Disease; Avicenna’s Tract of Cardiac Drugs and Essays on Arab Cardiotherapy. Scientific journal: Hamdard Medicus – informative articles by world authorities. Hamdard Foundation, Nazimabad, Karachi-18, Pakistan. ... hamdard national foundation, pakistan

Herb Pillow

To promote sleep. Fill linen bag with herbs: Hops, Chamomile, Bergamot, Basil, etc. Stitch together ends. Expose to heat before use. ... herb pillow

Indian Pennywort

See: GOTU KOLA. ... indian pennywort

Labelling Of Herbal Products By A Practitioner

Labelling regulations require every dispensed product, i.e. a container of medicine, lotion, tablets, ointment, etc, to be labelled with the following particulars:–

1. Name of the patient.

2. Name and address of the herbal practitioner.

3. Directions for use of the remedy.

4. Liquid preparations for local or topical use to be clearly marked: For external use only.

Statutory Instruments: Medicine (Labelling) Regulations 1976 No. 1726. Medicines (Labelling) Regulations 1977 No. 996. ... labelling of herbal products by a practitioner

Wood Betony Tea Panacea

Wood Betony Tea has been known since ancient time as an herb able to cure almost any affection (cure-all), from gastric aliments to nervous system deviations. Wood Betony is a perennial herb that grows mainly in areas like Eastern Europe, Asia and Africa. You can recognize it by its oval toothed-like green leaves and bright purple flowers. Also known as stachys officinalis, this herb never grows taller than 70 cm and it can be harvested for medical purposes only during the summer. In ancient times, people believed that wood betony had magical powers and that a ritual made using it could fulfill wishes. Wood Betony Tea Properties Scientific research showed that Wood Betony Tea is a good remedy not only when it comes to external and internal use, but also as a stress releaser and a great purifier. Its main ingredients include betaine, caffeic acid, chlorogenic acid, harpagide, rosmarinic acid, stachydrine and tannin, which, through their simultaneous action, can heal a large variety of diseases and aliments. Wood Betony Tea Benefits Wood Betony Tea shows its benefits in many areas of the alternative medicine. Not only that is a very good adjuvant in case you want to maintain a good general health, but it also triggers positive reactions from your body in cases of chronic and serious diseases. You may find Wood Betony Tea useful if you suffer from one of the following conditions: - Sore throat, due to flu or long term smoking. Wood Betony tea can clear your respiratory system and also give you a boost of energy. - Headaches or severe migraines, thanks to its wonderful ingredients that prevent inflammations and treat localized pain. - Anxiety, by calming the nerves and increasing the natural endorphins level. - Elevated blood pressure, elevated cholesterol and elevated blood flow. Wood Betony Tea can ease your natural reactions down by inhibiting negative reactions from your heart and brain. - Severe diarrhea and other problems of the digestive track, by fighting bacteria and all possible microbial accumulations. How to make Wood Betony Tea Infusion When preparing Wood Betony Tea infusion, you need freshly picked or dried herbs that you can buy from almost any teashop. Use about 1 teaspoon of herbs for every cup of tea you want to make, add boiling water and wait for 10 minutes. Strain and drink it hot or cold, keeping in mind the fact that this is a medical treatment and cannot replace your coffee habit. Wood Betony Tea Side Effects When taken properly, Wood Betony Tea has no side effects at all. However, high dosages may lead to a series of health problems, such as ulcers, gastritis and nausea. If you’ve been taking Wood Betony Tea for a while and you’re experiencing some unusual reactions, ask for medical help as soon as possible! Wood Betony Tea Contraindications Don’t take Wood Betony Tea if you’re pregnant or breastfeeding. It may lead to uterine contractions and internal bleeding. Also, avoid any treatment based on Wood Betony Tea if you’re preparing for a surgery or need to take blood thinners or anti-coagulant. Children under 2 years should not take this tea since the risks in this case remain unknown. However, if you have your doctor’s approval and you feel confident enough to give it a try, add it to your shopping cart next time you’re in a teashop and enjoy the wonderful benefits of this tea responsibly!... wood betony tea panacea

Xylopia Parviflora

Hook. f. Thoms.

Family: Annonaceae.

Habitat: Evergreen forests of Kerala up to an altitude of 600 m.

Folk: Saanthu, Kalpottan (Kerala), Kalpootha, Chiddavintai (Tamil Nadu), ulli (Karnataka).

Action: Root bark—antiseptic, used for ulcers. Root bark, flowers, fruits—used for oral hygiene.

Fruits of Xylopia aromatica are chewed with betel leaves; also used in cough and cold. The fruits, known as Suvaali Pippali, have no relationship with Pippali of Indian medicine. The plant contains pinenes.... xylopia parviflora

Yellow Fever Vaccine Is Prepared From

chick embryos injected with the living, attenuated strain (17D) of pantropic virus. Only one injection is required, and immunity persists for many years. Re-inoculation, however, is desirable every ten years. (See YELLOW FEVER.)

Haemophilus vaccine (HiB) This vaccine was introduced in the UK in 1994 to deal with the annual incidence of about 1,500 cases and 100 deaths from haemophilus MENINGITIS, SEPTICAEMIA and EPIGLOTTITIS, mostly in pre-school children. It has been remarkably successful when given as part of the primary vaccination programme at two, three and four months of age – reducing the incidence by over 95 per cent. A few cases still occur, either due to other subgroups of the organism for which the vaccine is not designed, or because of inadequate response by the child, possibly related to interference from the newer forms of pertussis vaccine (see above) given at the same time.

Meningococcal C vaccine Used in the UK from 1998, this has dramatically reduced the incidence of meningitis and septicaemia due to this organism. Used as part of the primary programme in early infancy, it does not protect against other types of meningococci.

Varicella vaccine This vaccine, used to protect against varicella (CHICKENPOX) is used in a number of countries including the United States and Japan. It has not been introduced into the UK, largely because of concerns that use in infancy would result in an upsurge in cases in adult life, when the disease may be more severe.

Pneumococcal vaccine The pneumococcus is responsible for severe and sometimes fatal childhood diseases including meningitis and septicaemia, as well as PNEUMONIA and other respiratory infections. Vaccines are available but do not protect against all strains and are reserved for special situations – such as for patients without a SPLEEN or those who are immunode?cient.... yellow fever vaccine is prepared from

Little Liver Pills

For bilious headache, inactive liver, constipation.

Ingredients: Aloin gr. 1/10. Ipom resin gr. 1/10. Capsic gr. 1/50. Podoph. resin. gr. 1/10. Jalapin gr. 1/10. Olearesin. Ginger. gr. 1/70.

Dose: One or two pills at bedtime or after dinner.

Historical interest only. ... little liver pills

Martindale, The Extra Pharmacopoeia

The world’s most comprehensive source of drug information in a single volume. Provides an accurate and concise summary of the properties, actions, and uses of plant and other medicines in clinical use. All information evaluated by expert editorial staff of the Pharmaceutical Society of Great Britain. ... martindale, the extra pharmacopoeia

Abortion – To Prevent

Disruptive termination of pregnancy before twenty-eighth week. Too premature expulsion of contents of the pregnant womb may be spontaneous, habitual, or by intentional therapy. Untimely onset of uterine contractions with dilation of cervical os (mouth of the womb) dispose to abortion. Essential that services of a suitably qualified doctor or obstetrician be engaged. It would be his responsibility to ensure that the embryo (unborn baby) and the placenta (after birth) are completely expelled.

Alternatives. Tea: equal parts – Agnus Castus, Ladysmantle, Motherwort, Raspberry leaves, 1-2 teaspoon to each cup boiling water; infuse 5-10 minutes; 1 cup 2-3 times daily.

Tablets/capsules. Cramp bark, Helonias.

Powders. Formula. Combine Blue Cohosh 1; Helonias 2; Black Haw 3. Dose: 500mg (two 00 capsules or one-third teaspoon) thrice daily.

Practitioner. Tincture Viburnum prunifolium BHP (1983), 20ml; Tincture Chamaelirium luteum BHP (1983) 20ml; Tincture Viburnum opulus BHP (1983), 20ml; Tincture Capsicum, fort, BPC 1934, 0.05ml. Distilled water to 100ml. Sig: 5ml tds pc c Aq cal.

Black Cohosh. Liquid Extract Cimicifuja BP 1898, 1:1 in 90 per cent alcohol. Dosage: 0.3-2ml. OR: Tincture Cimicifuja, BPC 1934, 1:10 in 60 per cent alcohol. Dosage: 2-4ml.

Squaw Vine (mother’s cordial) is specific for habitual abortion, beginning soon after becoming pregnant and continuing until the seventh month. Also the best remedy when abortion threatens. If attended by a physician for abortion, a hypodermic of morphine greatly assists; followed by Liquid Extract 1:1 Squaw Vine. Dosage: 2-4ml, 3 times daily.

Liquid extracts. Squaw Vine, 4 . . . Helonias, 1 . . . Black Haw bark, 1 . . . Blue Cohosh, 1. Mix. Dose: One teaspoon every 2 hours for 10 days. Thereafter: 2 teaspoons before meals, 3 times daily. Honey to sweeten, if necessary. (Dr Finlay Ellingwood)

Abortion, to prevent: Cramp bark, (Dr John Christopher)

Evening Primrose. Two 500mg capsules, at meals thrice daily.

Diet: High protein.

Vitamins. C. B6. Multivitamins. E (400iu daily).

Minerals. Calcium. Iodine. Iron. Selenium, Zinc. Magnesium deficiency is related to history of spontaneous abortion; magnesium to commence as soon as pregnant.

Enforced bed rest. ... abortion – to prevent

Anaemia: Pernicious

A form of anaemia following a deficiency of Vitamin B12. Usually occurs middle life, 45-60.

Symptoms. Skin of yellow tinge, failing eyesight, swollen ankles, feeble heart action, numbness of feet and legs, dyspepsia, tingling in limbs, diarrhoea, red beefy sore tongue, patches of bleeding under skin, unsteadiness and depression.

Treatment. Hospitalisation. Intramuscular injections of Vitamin B12. Herbs known to contain the vitamin – Comfrey, Iceland Moss. Segments of fresh Comfrey root and Garlic passed through a blender produce a puree – good results reported.

Alternatives:– Teas: Milk Thistle, Hops, Wormwood, Betony, White Horehound, Motherwort, Parsley, Nettles, Centuary.

Formula. Combine Centuary 2; Hyssop 1; White Horehound 1; Red Clover flower 1; Liquorice quarter. 1-2 teaspoons to each cup boiling water, infuse 15 minutes. 1 cup thrice daily.

Decoction. Combine Yellow Dock 1; Peruvian bark quarter; Blue Flag root quarter; Sarsaparilla 1; Bogbean half. 1 teaspoon to each cup of water, or 4oz (30 grams) to 1 pint (half litre) water. Simmer gently 10-15 minutes in covered vessel. Dose: Half-1 cup, thrice daily.

Decoction. Combine Yellow Dock 1; Peruvian bark quarter; Blue Flag root quarter; Sarsaparilla 1; Bogbean half. 1 teaspoon to each cup of water, or 4oz (30 grams) to 1 pint (one-half litre) water. Simmer gently 10-15 minutes in covered vessel. Dose: Half-1 cup, thrice daily.

Tablets/capsules. Echinacea, Dandelion, Kelp.

Powders. Formula. Equal parts: Gentian, Balm of Gilead, Yellow Dock. Dose: 500mg (two 00 capsules or one-third teaspoon), thrice daily before meals.

Liquid Extracts. Combine, Echinacea 2; Gentian 1; Dandelion 1; Ginger quarter. Dose: 15-30 drops in water thrice daily.

Gentian decoction. 1 teaspoon dried root to each cup cold water.

Diet. Dandelion coffee. Calves’ liver. Absorption of nutritious food may be poor through stomach’s inability to produce sufficient acid to break down food into its elements. Indicated: 2-3 teaspoons Cider vinegar in water between meals. Contraindicated – vegetarian diet.

Supplements. Vitamin B12, (in absence of injections). Iron – Floradix. Desiccated liver. Vitamin C 1g thrice daily at meals. Folic acid. 400mcg thrice daily. ... anaemia: pernicious

Menstruation, Prolonged

 May be caused by a decline in hormone levels. Indicated: Agnus Castus, Black Cohosh.

See: MENORRHAGIA. ... menstruation, prolonged

Olbas Pastilles

Oil Eucalyptus 1.16 per cent, Oil Peppermint 1.12 per cent, Menthol 0.1 per cent, Oil Juniper berry 0.067 per cent, Oil Wintergreen 0.047 per cent, and Oil Clove 0.0025 per cent. Respiratory obstruction and cough. (Lane’s, UK) ... olbas pastilles

Over-the-counter Products

Herbal products are chiefly used to relieve symptoms of self- limiting conditions. Such products are either P (pharmacy only) or GSL (General Sales List). The Medicines (Labelling and Advertising to the Public) Regulations 1978 (SI 1978 No 41) state the range of conditions on schedule 2, parts I-IV. Dried herbs on sale under their plant or botanical name over the counter are exempt, provided no medicinal claims are made. ... over-the-counter products

Analgesics  - Pain-relievers - Anodynes

Herbs taken orally for relief of mild pain. May also be applied externally. An analgesic may also be an antispasmodic, relieving cramp (Cramp bark etc.). Throughout history, Opium Poppy has always been the most effective analgesic, but must be given by a qualified medical practitioner except applied externally as a poultice. The same rule may apply to Aconite, Arnica and Belladonna.

Mild analgesics:– Black Cohosh, Black Willow, Catnep, Chamomile, Cowslip root (Bio-Strath), Cramp bark, Devil’s Claw, Gelsemium, Guaiacum, Hops, Jamaican Dogwood, Ladyslipper, Lobelia, Passion flower, Rosemary, Skullcap, St John’s Wort, Skunk Cabbage, Valerian, White Willow bark, Wild Lettuce, Wild Yam, Wintergreen, Yerbe Mate tea, Poke root, White Poplar.

Skullcap, Mistletoe, Valerian and Feverfew are herbs of choice. All four are believed to have an anti- prostaglandin effect, the first three given in combination; the latter (Feverfew) appearing to work best singly. ... analgesics  - pain-relievers - anodynes

Arthritis – Psoriatic

A form of joint erosion possible in patients with psoriasis; fingers and toes being most susceptible. Nails may be pitted with deep ridging. Bony structures are at risk where in close contact with septic psoriasis.

Alternatives:– Teas. Gotu Kola, Red clover flowers, Chickweed. Singly or in combination. 1 heaped teaspoon to each cup boiling water: infuse 5-10 minutes. 1 cup thrice daily.

Decoction. Fine cut: Burdock 2; Horsetail 1; Echinacea 1; Thuja quarter. Mix. 1oz to 1 pint water gently simmered 15 minutes. Wineglassful (or half a cup) thrice daily, before meals.

Tablets/capsules. Echinacea, Poke root, Prickly Ash bark.

Powders. Formula. Sarsaparilla 1; Echinacea 1; Boneset half; Thuja quarter. Dose: 500mg (two 00 capsules or one-third teaspoon) thrice daily.

Liquid extracts. Formula. Equal parts: Echinacea, Devil’s Claw, Gotu Kola. Dose: 30-60 drops thrice daily before meals.

Tinctures. Formula. Burdock 2; Echinacea 1; Boneset 1; Sarsaparilla 1; Thuja quarter. Fennel quarter. Mix. Dose: 1-2 teaspoons thrice daily.

Cod Liver oil.

Topical. Comfrey poultice, Chickweed cream, Oils of Mullein, Jojoba or Evening Primrose.

Diet. Oily fish (or fish oils). Low salt, low fat.

Supplements. Vitamins A, B-complex, C, D, E, Magnesium, Sulphur, Zinc. ... arthritis – psoriatic

Blood Purifiers

Alteratives. The blood is a fluid from which every variety of cell and tissue derives its special form of food for the repair of constant wastage resulting from functions they perform. When the blood becomes vitiated from lack of exercise, too little oxygen, debilitating personal habits and sophisticated foodstuffs the whole body suffers. The vital fluid then needs to be cleansed of its impurities. Nature’s blood purifiers are unique in the world of medicine, restoring biochemical balance and promoting healthy elimination.

Blood tonic. Decoction, tablets, tinctures or fluid extracts:– Echinacea 3; Burdock 2; Goldenseal 1. See also: ALTERATIVES. ... blood purifiers

Breast (female) Tenderness, Pain

May be from hormonal imbalance for which Agnus Castus is almost specific.

Rosemary. 1 teaspoon leaves to cup boiling water; infuse 15 minutes. Half-1 cup 2-3 times daily.

Tea. Formula. Equal parts leaves, Agnus Castus, Rosemary, Balm. 1-2 teaspoons to each cup boiling water; infuse 15 minutes; 1 cup 2-3 times daily.

Evening Primrose oil. 10 drops (or 2 × 250ml capsules) 3 times daily.

Poke root. Internally and externally.

Yorkshire gypsy device: fix a cabbage or a rhubarb leaf beneath brassiere.

Liquid Extract Blue Cohosh BHP (1983): 0.5-1ml, Thrice daily. Alternative: Liquid Extract Rosemary BHP (1983): 2-4ml. Thrice daily.

Vitamins. All-round multivitamin and mineral supplement. Vitamin C (1g daily). Vitamin E (400iu daily). ... breast (female) tenderness, pain

Pacho Tea

Inca cancer cure. See: LAPACHO TREE. ... pacho tea

Paget’s Disease Of The Nipple

Cancer of the mammary ducts (rare). Nipple: encrusted, red, inflamed. See: CANCER OF THE BREAST. ... paget’s disease of the nipple

Pain-relievers

See: ANALGESICS. ... pain-relievers

Palma Christi

See: CASTOR OIL. ... palma christi

Pancreatant

An agent to influence activity of the pancreas. Barberry, Goat’s Rue, Mountain Grape, Karela, Fringe Tree. All bitters have a toning effect on the pancreas. ... pancreatant

Paracetamol Toxicity

For symptoms of overdosing or withdrawal from Paracetamol when discontinued, nervines are sometimes of value.

To break dependency: White Willow bark, Guaiacum, Oats, Passion flower.

Overdosing may cause liver damage for which Fringe Tree bark is indicated. Nutrients: Vitamins B-complex, C. Zinc. ... paracetamol toxicity

Caffeine Poisoning

A Harvard study links coffee consumption with cancer of the pancreas. No association has been found between tea-drinkers and cancer. Some authorities claim coffee is not carcinogenic until roasted.

While an internal mechanism slows down the body, caffeine in tea, cola and coffee restores alertness. Caffeine acts by blocking the action of the compound, adenosine – one of the building blocks of DNA which promotes cell energy. Caffeine interferes with natural metabolic processes. In the aged, coffee increases production of uric acid, causing irritation of the kidneys, joint and muscle pains. vCaffeinism is responsible for a wide range of disorders. Increases the heart beat, promotes excessive stomach acid and increases flow of urine. It may give rise to birth defects and should be taken with caution in pregnancy.

Symptoms. Restlessness, nervous agitation, extreme sensitiveness. Intolerance of pain, nervous palpitation, all senses acute.

To antidote. Chamomile tea.

Practitioner. Tincture Nux vom BP: 10 drops to 100ml water. Dose: 1 teaspoon thrice daily. Inhalation: Strong spirits of Camphor.

Diet. Plenty asparagus. ... caffeine poisoning

Californean Poppy

Eschscholtzia californica (Cham.) French: Globe du soleil. German: Goldmohn. Italian: Escolzia di California. Whole plant. Practitioner use.

Constituents: flavone glycosides.

Action: hypnotic, sedative, nerve relaxant, anodyne.

Uses: Insomnia, migraine, stressful conditions, nervous bowel, anxiety, depression, neuralgia. Combines well with Passion Flower (equal parts) for hyperactivity and sleeplessness.

Preparations: Tea. 1 teaspoon to each cup boiling water; infuse 15 minutes; morning and evening. Powder: capsule: 240mg. 2 capsules middle of afternoon; 4 capsules evening one hour after going to bed. (Arkocaps) ... californean poppy

Cancer – Pancreas

Adeno-carcinoma. Cause: often related to chronic pancreatitis, alcoholism. Beer drinkers, more than 7 pints a week, run a three times greater risk of the disease than one in a 100 threat to the rest of the population. (Imperial Cancer Research Report, April, 1989) Diabetes. A study carried out at Harvard School of Public Health found strong evidence in favour of the excessive consumption of coffee. Seventh Day Adventists and Mormons, who abstain from coffee, have much lower rates than the average. Relative risk was 1-8 with up to two cups a day and 2.7 with three or more. (New England Journal of Medicine, 1981, March 12, Vol 304, No 11, p630)

Symptoms. Weight loss. Pain upper abdomen. Change of bowel habit. Phlebitis. Low blood sugar. Sugar in the urine. Jaundice when head of the pancreas is involved. As little benefit is said to be gained from chemotherapy or radiotherapy, and because a majority of these tumours are unresectable, there would appear to be good grounds for herbal medicine, either as primary or supportive treatment.

Of possible therapeutic value for relief of accompanying gastric and pressure symptoms only: Sarsaparilla, Liquorice, Dandelion, Peppermint, Fennel, German Chamomile.

Tea. Barberry bark. 1 teaspoon to each cup of cold water. Steep overnight. Dose: half-1 cup 3 or more times daily.

Formula. Equal parts: Barberry bark, Dandelion, Galangal. Dose: Powders: 500mg (two 00 capsules or one-third teaspoon). Liquid extracts: 1 teaspoon (5ml). Tinctures: 2 teaspoons. Thrice daily to commence: after fourteen days increase as tolerated.

Primrose oil. High doses GLA believed to improve immune system and prevent weight loss.

Macrobiotic diet. A retired English doctor had cancer of the pancreas, inoperable, the size of a cricket ball, for which conventional treatment could do nothing. Regression being almost impossible, he would die within a few months. In the meantime he was advised to try the Macrobiotic diet comprising wholefoods, compost grown vegetables, vegetable oils and natural drinks such as carrot juice and herbal teas. He and his wife, living in Italy, carefully followed the diet, drank water only from a local spring and ate vegetables organically grown on their own land. The tumour diminished in size and the doctor recovered.

Note: Cessation of cigarette smoking will result in a decreased incidence of the disease in the male adult population. (American Journal of Public Health 1989 79 1016)

A substance found in fish oil has been shown experimentally to prevent cancer of the pancreas. Mackerel, herring and sardines are among fish with the ingredient.

Treatment by oncologist or general practitioner. ... cancer – pancreas

Parasiticides

Herbs that destroy animal or vegetable parasites in the alimentary canal, on the head or skin.

Aniseed, Benzoic acid as in Storax and the balsams of Tolu and Peru. Chaparral, Cinnamon oil, Garlic, Poke root, Rosemary, Rue, Thymol (oil of Thyme), Sassafras oil. (Topical use only) Quassia chips (cold infusion for head lice, fleas, scabies. ... parasiticides

Paratyphoid

A form of enteric fever caused by bacteria of the Salmonella group. A notifiable disease. Treatment the same as for TYPHOID FEVER. ... paratyphoid

Parkinson, John

 1567-1650. Apothecary to two kings; first James I. When Charles I came to the throne he was named Botanicus Regis Primarius. Books: Paradise in Sole Paradisus Terristris (1629). It was a pun on his name: Park-in-suns Earthly Paradise, and referred to as a ‘speaking garden’. Theatre of Plants (1640). Describes 3,800 plants. A herbal in every sense of the word; most comprehensive in the English language. ... parkinson, john

Aggregation, Platelet

The clumping together of platelets (small, sticky blood particles). Aggregation is the 1st stage of blood clotting and helps to plug injured vessels. Inappropriate aggregation can have adverse effects; for example, if aggregation occurs in an artery, it may result in a thrombosis.... aggregation, platelet

Cancer – Prostate Gland

Adeno-carcinoma. A hormone-related tumour in elderly men. Enlargement of the gland may be benign or carcinomatous. Fibrosis (hardening) may arise from inflammation. Obstruction of the outlet of the bladder through swelling of the gland (prostatism) may cause uraemia.

Symptoms. Bladder irritability; increased frequency during the night. Feeble forked stream of urine. Sometimes blood. Three quarters of such tumours are located in the posterior lobe of the prostate gland – readily accessible to the examining finger through the front wall of the rectum. Rectal examination reveals a hard rugged prostate. Cystoscopy confirms. Bone pains in the low back or pelvis reflect a stage where the tumour has already spread. Anaemia, weight loss, urgency.

All symptoms are worse by alcohol and spicy foods.

Harvard University scientists report: heavy consumption of animal fat, especially the fat in red meat appears to increase the chance that a man will develop advanced prostate cancer.

Of therapeutic value. Comfrey, Echinacea, Horsetail, Poke root, Thuja, Cornsilk, Goldenseal.

Tea. Combination. Comfrey leaves, Horsetail, Cornsilk. Equal parts. 2-3 teaspoons to each cup boiling water. Drink freely.

Formula No. 1. Echinacea 2; Comfrey 1; Poke root half; Thuja half. Mix. Dose: Powders: 500mg (two 00 capsules or one-third teaspoon). Liquid extracts: 1 teaspoon. Tinctures: 2 teaspoons. Thrice daily in water or cup of Cornsilk tea.

Formula No. 2. (Alternative) Echinacea 2; Goldenseal 1; Gotu Kola 1; Poke root half. Mix. Dose: Powders: 500mg (two 00 capsules or one-third teaspoon). Liquid extracts: 1 teaspoon. Tinctures: 2 teaspoons in water or cup of Cornsilk tea.

Bee pollen. Of value.

Garlic. Of value.

Diet. See: DIET – CANCER.

There is a very low incidence of prostate cancer in countries where Soya products are widely consumed – Soya contains a female hormone which is a protector factor.

Supplements. Morning and evening.

Vitamin A 7500iu or more. Large doses may be required. Vitamin C 1-2g. Vitamin E 200iu. Calcium 500mg. Selenium 100mcg. Zinc.

Study. Men with prostate cancer may not need to undergo radical prostatectomy (removal of the prostate gland). A 10-year follow-up study of men with early prostate cancer left untreated showed that 10 years later only 8.5 per cent of the 223 patients had died from prostate cancer. The survival rate of 86.8 per cent in the untreated group was nearly identical to a subgroup who met all the conditions for radical prostatectomy. (Journal of American Medical Association, 22/29 April 1992)

Commonly treated with female sex hormone or by orchidectomy.

It would appear that surgical removal of the gland offers little benefit, and possibly a disadvantage to patients wishing to leave well alone, particularly the elderly. Treatment by a general medical practitioner or oncologist. ... cancer – prostate gland

Cancer – Pulmonary

Cancer of the lung.

By the blood and lymph cancer may be transferred (metastasised) to the lymph nodes under the arm, liver, brain or lungs. An association has been shown between a low intake of Vitamin A and lung cancer. Causes: occupational hazards, environmental pollution, radiation, keeping of pet birds. Cigarette smoking is a strong risk factor. Studies show that a high Vitamin A/carotene intake is protective against the disease in men. Among women, evidence of a similar protective effect has not been found. Vitamin C reduces cancer risk. The increased prevalence of smoking among women results in more female lung cancer. All smokers should drink freely carrot juice (Vitamin A).

Symptoms. Chronic irritative cough, difficult breathing, pain in the chest, recurrent spitting of blood, clubbing of fingers, weight loss.

Alternatives. Only transient benefit is obtainable, yet it may be sufficient to achieve a measure of relief from distressing symptoms. See: CANCER: GENERAL REMARKS. Mullein tea has its supporters. Bugleweed strengthens lung tissue and supports the action of the heart. Blood root is known to arrest bleeding (haemoptysis).

Tea. Equal parts: Red Clover, Gota Kola, Mullein. 2 teaspoons to each cup boiling water; infuse 5-15 minutes. 1 cup three or more times daily.

Formula No 1. Equal parts: Elecampane, Violet, Red Clover, Echinacea. Mix. Dose: Powders: 750mg (three 00 capsules or half a teaspoon). Liquid extracts: 1-2 teaspoons. Tinctures: 1-3 teaspoons. Thrice daily and, if necessary, at bedtime for relief.

Formula No 2. Tincture Blood root 10 drops; Liquid extract Dogwood 20 drops; Liquid extract Elecampane 200 drops (14ml); Liquid extract Bugleweed (Lycopus europ) 30 drops. Flavour with Liquorice if necessary. Dose: 1-2 teaspoons in water 3 or more times daily. (W. Burns-Lingard MNIMH)

Where accompanied by active inflammation, anti-inflammatories are indicated: Mistletoe, Wild Yam, etc.

Diet. A substance in fish oil has been shown to experimentally prevent cancer of the lung. Mackerel, herring and sardines are among fish with the ingredient. See: DIET – CANCER.

Chinese Herbalism. See: CANCER – CHINESE PRESCRIPTION.

Treatment by a general medical practitioner or hospital oncologist. ... cancer – pulmonary

Air Pollution

See pollution.... air pollution

Alveolus, Pulmonary

One of a large number of tiny, balloon-like sacs at the end of a bronchiole (one of many small air passages in the lungs) where gases are exchanged during respiration.... alveolus, pulmonary

Anaemia, Pernicious

See anaemia, megaloblastic.... anaemia, pernicious

Analysis, Psychological

See psychoanalysis.... analysis, psychological

Antifreeze Poisoning

Most antifreeze in the contains ethylene glycol, which is poisonous.

Drinking antifreeze initially produces effects similar to alcohol intoxication, but vomiting, stupor, seizures, and coma may follow; acute kidney failure may occur within 24–36 hours.

Antifreeze poisoning requires immediate medical attention.... antifreeze poisoning

Castor Oil Plant

Palma Christi. Ricinus communis L. Part used: oil expressed cold drawn from the seeds without the aid of heat. Versatile agent for skin diseases. “Biochemical precursor of prostaglandins . . . a trigger mechanism to immune system T-cells in the skin causing them to activate a local immune system reaction through the lymphatics.” (Harvey Grady, Edgar Cayce Foundation, Virginia Beach, Va., USA)

Action: anti-allergenic, galactagogue. Canary Island nursing mothers bind leaves to the breast to increase secretion of milk. Vitality of cells is upgraded by contact with the oil. Oral contraceptive. (V.J. Brondegaard, Plants Med. 23, 167, 1973) A traditional purgative.

Uses: Internal. Rarely used, except for varied forms of allergy (penicillin, hay fever, etc): 5 drops oil in honey, 3-4 times daily. Mouth ulcers, smear with oil. Large doses avoided.

Topical. Anti-fungal, emollient, anodyne.

Application to warts, corns, bunions, skin disorders, psoriasis, eczema, nail infection, bedsores, pigmented mole, ringworm, itch, ear-infection in children (drops), leg ulcers – dab with smear for pain relief, rodent ulcers made bearable, gangrene (with tincture Myrrh drops). Oil massaged into scalp for 20 minutes daily for falling hair. Eyelids, to soothe and heal. Age spots: brown patches on face, arms or hands have been known to disappear when persevering with a smear of each – Castor oil and Bicarbonate of Soda.

Preparations: Internal use: oil – 5 to 20ml, as prescribed.

External use: Zinc and Castor oil cream, or ointment. Or, Castor oil only.

Castor oil pack, to stimulate the immune system: apply soft pad of material saturated with Castor oil; hold in position with elastic bandage for skin diseases, pains of arthritis or rheumatism; lacerated and well-sutured wounds that refuse to heal. Renew oil when pad becomes dry. Oil may be used as a vehicle for eye drops. ... castor oil plant

Chelsea Physic Garden

Started by the Worshipful Society of Apothecaries 1673, the Chelsea Physic Garden is the second oldest herb garden in England devoted to the scientific study of plants. It provides a silent four-acre oasis in the heart of London for enjoyment by the public, but especially for research into herbs. For over 300 years the garden has supplied drugs to London doctors for relief of the sick.

Records provide one of the few sources of information about medicinal plants in cultivation during the 18th century. The famous gardener Philip Miller took over in 1722 and developed it as the finest botanic garden in the world for its amazing variety of plants. In the 18th century cotton seeds were sent from the garden to form the crop of the new colony of Georgia, America.

From Chelsea, Madagascan Vinca rosea was distributed and which earned a place in modern medicine (vinplastine) for the treatment of leukaemia. After many years neglect, medical botany enjoys a renaissance during which the skills of the garden’s scientific staff are again in demand for the training of pharmacists and students of other disciplines. Its buildings house a valuable collection of botanical books, including John Parkinson’s “Paradisus”. ... chelsea physic garden

Composition Powders

Alternatives.

1. Powders: 3oz Bayberry, 1oz Ginger, half Cinnamon, half an ounce Cloves, quarter of an ounce Cayenne. Sift. Mix. (E.G. Jones MNIMH)

2. 2oz Bayberry, 1oz Ginger, 1oz Pleurisy root, half an ounce Cayenne. Sift. Mix. (Melville C. Keith MD) 3. 2oz Poplar bark, 1oz Balmony herb, half an ounce Goldenseal, half an ounce Cinnamon, three-quarters of an ounce Cayenne. Mix. Sift. “This brought the American physiomedical doctors immortal fame.” (F.H. England MD)

Dose: Quarter to 1 teaspoon in hot water, tea or honey. The powder may be fed into 00 capsules: 2-4 capsules swallowed or taken as above.

Composition powder is a harmless stimulant against winter’s ills, influenza and for the first stages of fevers. Long traditional reputation for stomach and bowel disorders, cramp, collapse, circulatory stasis, fainting, hypothermia, to promote perspiration, to assuage moderate degree pain. In the elderly it was given to rekindle the fires of life when burning low. ... composition powders

Depression – Post-natal

Extreme anguish after birth of a child. Mental illness: “sinking into gloom”. Baby blues. Bursting into tears; every small problem seems magnified; agoraphobic tendency. Etiology. Some mothers have a genetic predisposition to the condition. Death of a close relative, stressful pregnancy, redundancy, moving house, or sheer physical and mental exhaustion.

Treatment. Conventional medicine advises strong anti-depressants. Alternatives, until “hormones settle down”: Agnus Castus, Helonias, Milk Thistle. Raspberry leaf tea (tablets/capsules/liquid extracts/tinctures). Special attention to the thyroid gland.

Diet. See: GENERAL DIET.

Supplements. Vitamins: B group, E. Minerals: Calcium, Iodine, Magnesium, Zinc. Tyrosine. Supportives: Astute GP, helpful health visitor, thoughtful husband. ... depression – post-natal

Binge–purge Syndrome

An alternative term for bulimia.... binge–purge syndrome

Borderline Personality Disorder

A personality disorder that falls between neurotic and psychotic levels. Mood changes are often rapid and inappropriate. Angry outbursts are common, as are impulsive, self-damaging acts such as gambling or suicide attempts.... borderline personality disorder

Breast Pump

A device used to draw milk from the breasts in order to relieve overfull breasts during lactation, to express milk for future use, or to feed a baby who is unable to suckle.... breast pump

Chlorate Poisoning

The toxic effects of chemicals present in some defoliant weedkillers. Ingesting chlorates can cause kidney and liver damage, corrosion of the intestine, and methaemoglobinaemia (a chemical change in haemoglobin in the blood). Small doses of chlorates can prove fatal. Symptoms of poisoning include ulceration in the mouth, abdominal pain, and diarrhoea.... chlorate poisoning

Code Of Practice

National Institute of Medical Herbalists.

1. It is illegal for anyone not a registered medical practitioner to attempt to procure an abortion: a member must not knowingly administer an abortifacient or known uterine muscle stimulant remedies to a pregnant patient, nor instruments for the purpose of procuring an abortion, nor assist in any illegal operation.

2. It is required that any intimate examinations on a patient of the opposite sex be conducted in the presence of a relative of the patient or a suitable assistant.

3. A member must not treat or prescribe any remedy for gonorrhoea, syphilis, or urinary affections of a venereal nature.

4. It is the duty of the practitioner to notify the District Medical Officer regarding any disease on the current list of notifiable diseases. In cases of industrial poisoning or accident the local district branch of the Health and Safety Executive should be notified.

5. A member must consider very carefully the implications of recommending a course of treatment contrary to the advice of the patient’s registered medical practitioner or of not recommending referral to a registered medical practitioner in the case of serious disease or uncertain diagnosis. Members must be aware of their vulnerability in law on this issue and must ensure in such a case that all available information is given to the patient and that the patient makes the final decision without coercion.

6. A parent or supervising adult must be present at any treatment or examination of a child under the age of 16, or of a mentally-retarded patient.

7. The Data Protection Act means that any practitioner keeping patient’s data on computer file must register under the terms of the Act.

8. A member must become familiar with the terms of the Medicine’s Act 1968 and subsequent statutory instruments, notably the Medicines (Retail Sale or Supply of Herbal Remedies) Order 1977. Particular care should be taken to become familiar with the statutory maximum doses of those remedies listed in Schedule III of the latter order. Detailed records of prescriptions and dispensing must also be kept.

9. The Medicines Act further states that to claim exemptions from the restrictions on the supply of certain herbal remedies, the practitioner should supply said remedies from premises occupied by the practitioner and able to be closed so as to exclude the public.

10. The Medicines Act adds that to claim the said exemptions, the person supplying the remedy “sells or supplies it for administration to a particular person after being requested by or on behalf of that person and in that person’s presence to use his own judgement as to the treatment required”. The member should avoid treatment through telephone or postal contact, although repeat prescriptions may be supplied on this basis for a limited period.

11. Dispensing and labelling of medicines should at least comply with the terms of the Medicines Act. All medicines should be labelled to clearly indicate the correct dosage or other directions for use (especially for those remedies subject to a statutory maximum dose), and with the name and address of the practitioner and the date of dispensing.

12. A member should never claim verbally or in print to be able to cure any life-threatening or serious disease.

13. The distribution or display of letter headings, business cards or practice information should be compatible with the highest professional medical standards. ... code of practice

Ear Drums, Perforated

Sliced Garlic treatment. Peel corm, leaving transparent epithelial-layer attached. Cut slice and shape it to cover the perforation; push it against the eardrum so that its cut surface hugs the perforation. Pack the external auditory meatus with an alcohol-moistened plug of cotton wool. Water must not enter the ear and forceful nose-blowing avoided. Replace Garlic slice once or twice a week until healing is complete. If middle ear becomes inflamed with excessive exudate, stop treatment and give an anti-inflammatory (such as Echinacea, author). Any exudation usually stops when treatment is discontinued. (Chinese Medical Journal, May 1977) ... ear drums, perforated

European Pharmacopoeia

Legal status of. Under the 1964 Convention on the Elaboration of a European Pharmacopoeia the standards of the European Pharmacopoeia are required to take precedence over the standards of the national pharmacopoeias of the contracting parties, thus ensuring a common standard. In the United Kingdom this has been achieved by means of section 65(7) of the Medicines Act 1968. In addition to the United Kingdom the countries party to the Convention are Austria, Belgium, Cyprus, Denmark, Finland, France, German Federal Republic, Greece, Iceland, Ireland, Italy, Luxembourg, The Netherlands, Norway, Spain, Sweden, Switzerland and Portugal. (Mail 54, June 1988) ... european pharmacopoeia

Chondromalacia Patellae

A painful disorder of the knee in which the cartilage behind the patella (kneecap) is damaged.

Adolescents are most commonly affected.

The condition may result from knee injuries or sporting activities in which the knee is bent for long periods.

This action weakens the inner part of the quadriceps muscle (at the front of the thigh) causing the patella to tilt when the knee is straightened and rub against the lower end of the femur.

The cartilage that covers both bones becomes roughened, causing pain and tenderness.

Treatment is with analgesic drugs and exercises to strengthen the thigh muscles.

Rarely, surgery may be needed.... chondromalacia patellae

Co-proxamol

An analgesic drug containing paracetamol and the weak opioid analgesic dextropropoxyphene, widely used to relieve mild to moderate pain that has not responded to paracetamol or other nonopioid analgesics alone.

Side effects are dizziness, drowsiness, constipation, and nausea.

The drug may be habit-forming if taken over a long period.... co-proxamol

Defoliant Poisoning

The toxic effects of plant poisons that cause leaves to drop off.

Defoliants are poisonous if swallowed.

Widely used defoliants include sodium chlorate, potassium chlorate, phenoxy herbicides, and paraquat.... defoliant poisoning

Evening Primrose

Oenothera biennis L. German: Echte Nachtkerze. French: Onagre. Italian: Stella di sera. Keynote: Prostaglandin precursor. Unrefined oil is expressed from the seeds that yield gamma linolenic acid and an essential fatty acid. Whole plant is edible.

Action. Anticoagulant, nutritive, demulcent, anti-eczema. Reduces blood clotting time, which is of value for thrombosis. A precursor of Prostaglandin E1 which inhibits abnormal cell proliferation and reduces blood pressure. Reduces serum cholesterol levels. Externally: to protect moisture balance of the skin.

Use s. Stops platelet-clumping. Dilates coronary arteries and removes obstructions. Intermittent claudication. Raynaud’s disease. Said to slow down the progress of multiple sclerosis. Pre-menstrual tension and breast pain. Said to arrest rheumatoid arthritis in moderate cases. Prevention of liver damage. Dry scaly skin disorders; eczema, acne (with zinc). Soft brittle finger nails. Abnormal tear production. Hyperactive children. Mental depression. Diabetic retinitis. To allay the ageing process. Alleviates hangovers. Alcohol habit. Pruritus. Combined with Vitamin E which acts as a protective antioxidant. Trials have shown that the oil has significantly improved sensory function: muscle weakness, arm tendon reflex and numbness – which signs may be reversed in diabetes.

Preparations: “Efamol” 500: comprising 500mg Evening Primrose oil; 10mg natural Vitamin E. 4-6 capsules daily depending on requirement, for 6-8 weeks.

To maintain EFA and GLA levels. “Efamol” 250: comprising 250mg Evening Primrose oil; 200mg Safflower oil; 50mg Linseed oil; 10mg Vitamin E. 3-4 capsules daily, regularly.

Vitamins B6 and C; and minerals Magnesium and Zinc assist its action. Features in a wide range of cosmetic products as a moisturiser.

Poultice: leaves and flowers for abscesses, boils, etc.

Not given in epilepsy. ... evening primrose

Feet – Pain In

(Metatarsalgia)

Causes: foot-strain, deformity, osteoporosis, high heels throwing the body out of its normal posture, tight shoes.

Feet are often painful because one or more of the bones are out of alignment and which may be adjusted by simple osteopathy. The process can be assisted by foot-baths of Chamomile flowers, Arnica flowers, or Comfrey to relax muscles and tendons.

Alternatives. Alfalfa, Chaparral, Ligvites, Prickly Ash.

Topical. Aromatherapy. (Sensitive feet) Oils of Pine, Eucalyptus or Thyme – 6 drops, any one, to 2 teaspoons Almond oil. Warm. Massage into foot and wrap round with damp hot towel.

General. Acupuncture. Shoes should be bought in the afternoon, particularly if feet swell during the day. Shoes that fit well in the morning may have become too tight by tea-time. ... feet – pain in

Ginseng - King Plant

Panax schinseng, Nees. Panax ginseng. German: Gensang. French: Panax. Italian: Ginseng. Chinese: Huang shen. C.A. Meyer. Roots. More suited to men than women. Used as a medicine in the Far East for over 4,000 years. Source of natural steroids (oestrogens), raising natural immunity. All Ginsengs enhance the natural resistance and recuperative power of the body. Produces opposite effects; i.e. it is both sedative and stimulant; in some it raises, in others it lowers blood pressure. Raises some cholesterol factors while reducing the overall amount in the blood. Hypoglycaemic. Aphrodisiac. Heart tonic. Old age re-vitaliser. Adaptogen. Used by the People’s Republic of China for a wide range of disorders. Source of the element Germanium.

Constituents: gum, resin, starch, saponin glycosides, volatile oil.

Uses: Physical weakness, neurasthenia, recovery after surgery. Promotes physical and intellectual efficiency. A mood-raiser. Induces a feeling of well being and stability. Depression, sexual debility, sleeplessness. The sportsman’s remedy, improving running ability and endurance. Retards build-up of lactic acid which normally occurs during hard exercise and causes fatigue. Increases resistance to excess cold or heat exposure and to a working environment with a noisy background. Lessens side-effects of insulin in diabetes. To help the body adapt to a changed environment (jet lag). Enhances mental performance in students. Promotes biosynthesis of DNA and RNA.

Preparations: Miscellaneous products available. Single morning dose.

Decoction. Half-1 teaspoon to each cup water gently simmered 10 minutes, or added to a cup of domestic tea.

Powder. Half-1g daily.

Contra-indications: hyperactivity in children, pregnancy, high blood pressure, menopause. Not taken continuously but for periods from 1 week to 1 month. Should not be taken with coffee. ... ginseng - king plant

Dementia Praecox

An outdated term for severe schizophrenia, especially that affecting adolescents or young adults.... dementia praecox

Detergent Poisoning

The toxic effects that occur as a result of swallowing the cleaning agents in shampoos, laundry powders, and cleaning liquids.... detergent poisoning

Dual Personality

See multiple personality.... dual personality

Ear Piercing

Making a hole in the earlobe or another part of the external ear to accommodate an earring.... ear piercing

Ears, Pinning Back Of

See otoplasty.... ears, pinning back of

Emotional Problems

A common term for a range of psychological difficulties, often related to anxiety or depression, which may have various causes.... emotional problems

Eye, Painful Red

A common combination of eye symptoms that may be due to any of several eye disorders.

Uveitis is a common cause of dull, aching pain. The redness is caused by widening of blood vessels around the iris. Another serious cause of pain and redness in one eye is acute closedangle glaucoma. Other causes include keratitis, usually due to a corneal ulcer, or a foreign body in the eye (see eye, foreign body in). The most common cause of redness and irritation in the eye is conjunctivitis.... eye, painful red

Herbal Practitioner

WHAT THE LAW REQUIRES. The consulting herbalist is covered by Part III of The Supply of Herbal Remedies Order, 1977, which lists remedies that may be used in his surgery on his patients. He enjoys special exemptions under the Medicines Act (Sections 12 (1) and 56 (2)). Conditions laid down for practitioners include:

(a) The practitioner must supply remedies from premises (apart from a shop) in private practice ‘so as to exclude the public’. He is not permitted to exceed the maximum permitted dose for certain remedies, or to prescribe POM medicines.

(b) The practitioner must exercise his judgement in the presence of the patient, in person, before prescribing treatment for that person alone.

(c) For internal treatment, remedies are subject to a maximum dose restriction. All labels on internal medicines must show clearly the date, correct dosage or daily dosage, and other instructions for use. Medicines should not be within the reach of children.

(d) He may not supply any remedies appearing in Schedule 1. Neither shall he supply any on Schedule 2 (which may not be supplied on demand by retail).

He may supply all remedies included in the General Sales List (Order 2129).

(e) He must observe requirements of Schedule III as regards remedies for internal and external use.

(f) He must notify the Enforcement Authority that he intends to supply from a fixed address (not a shop) remedies listed in Schedule III.

(g) Proper clinical records should be kept, together with records of remedies he uses under Schedule III. The latter shall be available for inspection at any time by the Enforcement Authority.

The practitioner usually makes his own tinctures from ethanol for which registration with the Customs and Excise office is required. Duty is paid, but which may later be reclaimed. Accurate records of its consumption must be kept for official inspection.

Under the Medicines Act 1968 it is unlawful to manufacture or assemble (dispense) medicinal products without an appropriate licence or exemption. The Act provides that any person committing such an offence shall be liable to prosecution.

Herbal treatments differ from person to person. A prescription will be ‘tailored’ according to the clinical needs of the individual, taking into account race as well as age. Physical examination may be necessary to obtain an accurate diagnosis. The herbalist (phytotherapist) will be concerned not only in relieving symptoms but with treating the whole person.

If a person is receiving treatment from a member of the medical profession and who is also taking herbal medicine, he/she should discuss the matter with the doctor, he being responsible for the clinical management of the case.

The practitioner can provide incapacity certificates for illness continuing in excess of four days for those who are employed. It is usual for Form CCAM 1 5/87 to be used as issued on the authority of the Council for Complementary and Alternative medicine.

General practitioners operating under the UK National Health Service may use any alternative or complementary therapy they choose to treat their patients, cost refunded by the NHS. They may either administer herbal or other treatment themselves or, if not trained in medical herbalism can call upon the services of a qualified herbalist. The herbal practitioner must accept that the GP remains in charge of the patient’s clinical management.

See: MEDICINES ACT 1968, LABELLING OF HERBAL PRODUCTS, LICENSING OF HERBAL REMEDIES – EXEMPTIONS FROM. ... herbal practitioner

Labelling Of Herbal Products

The law requires labels to carry a full description of all ingredients. No label should bear the name of a specific disease or promote treatment for any serious disease or condition requiring consultation with a registered medical practitioner. Labels must not contravene The Medicines (Labelling and Advertising to the Public), SI 41, Regulations, 1978.

Misleading claims and the use of such words as “organic”, “wholesome”, “natural” or “biological” cannot be accepted on product labels. The Licensing Authority treats herbal manufacturers no differently than manufacturers of allopathic products for serious conditions.

The Advertising Standards Authority does not allow quotation of any medicinal claims, except where a Product Licence (PL) has been authorised by the Licensing Authority.

All labels must include: Name of product (as on Product Licence), description of pharmaceutical form (tablet, mixture etc), Product Licence No., Batch No., quantity of each active ingredient in each unit dose in metric terms; dose and directions for use; quantity in container (in metric terms); “Keep out of reach of children” or similar warning; Name and address of Product Licence Holder; expiry date (if applicable); and any other special warnings. Also to appear: excipients, method/route of administration, special storage instructions, and precautions for disposal, if any.

Where licences are granted, the following words should appear on the label of a product: “A herbal product traditionally used for the symptomatic relief of . . .”. “If symptoms persist see your doctor.” “Not to be used in pregnancy” (where applicable). “If you think you have . . . consult a registered medical practitioner before taking this product.” “If you are already receiving medical treatment, tell your doctor that you are taking this product.” These warnings are especially necessary should symptoms persist and be the start of something more serious than a self-limiting condition.

Herbal preparations should be labelled with the additives and colourings they contain, if any. This helps practitioners avoid prescribing medicines containing them to certain patients on whom they may have an adverse reaction.

Labels of medicinal products shall comply with the Medicines (Labelling) Regulations 1976 (SI 1976 No. 1726) as amended by the Medicines (Labelling) Amendment Regulations 1977 (SI 1977 No. 996), the Medicines (Labelling) Amendment Regulations 1981 (SI 1981 No. 1791) and the Medicines (Labelling) Amendment Regulations 1985 (SI 1985 No. 1558).

Leaflets issued with proprietory medicinal products shall comply with the requirements of the Medicines (Leaflets) Regulations 1977 (SI 1977 No. 1055).

See also: ADVERTISING: CODE OF PRACTICE. BRITISH HERBAL MEDICINE ASSOCIATION. ... labelling of herbal products

Gambling, Pathological

Chronic inability to resist impulses to gamble, resulting in personal or social problems.... gambling, pathological

Genetic Probe

A specific fragment of DNA that is used in laboratory tests to determine whether particular genetic defects are present in an individual’s DNA.

Genetic probes are mainly used in antenatal diagnosis of genetic disorders, and in investigating whether people with a family history of a genetic disorder carry the defective gene themselves.... genetic probe

Hepatectomy, Partial

Surgical removal of part of the liver.

Surgery may be needed to remove a damaged area of liver following injury, or to treat noncancerous liver tumours and hydatid disease.

Rarely, liver cancer is treated in this way.... hepatectomy, partial

Ice-packs

The means of applying ice to the skin (in a towel or other material) in order to relieve pain, stem bleeding, or reduce inflammation. Cold causes the blood vessels to contract, reducing blood flow. Ice-packs are used to relieve pain in a variety of disorders, including severe headache. They are used on sports injuries to minimize swelling and bruising, and they also help to stop bleeding from small vessels, as in a nosebleed. ... ice-packs

Idiopathic Thrombocytopaenic Purpura

(ITP) An autoimmune disorder in which platelets are destroyed, leading to bleeding beneath the skin (see purpura).... idiopathic thrombocytopaenic purpura

Ileus, Paralytic

A failure, usually temporary, of the normal contractility of the muscles of the intestine. Paralytic ileus commonly follows abdominal surgery and may also be induced by severe abdominal injury, peritonitis, internal bleeding, acute pancreatitis, or interference with the blood or nerve supply to the intestine. Symptoms include a swollen abdomen, vomiting, and failure to pass faeces. The condition is treated by resting the intestine. A tube passed through the nose or mouth into the stomach or intestine removes accumulated fluids and keeps the stomach empty. Body fluid levels are maintained by intravenous infusion (drip).... ileus, paralytic

Opium Poppy

Papaver somniferum L. Prescription by a medical practitioner only. Contains morphine alkaloids and codeine. Analgesic, narcotic.

Although medication with opiates is addictive and its abuse ranges from dependence to death, use of crushed poppyheads as a topical poultice for crippling pain, as in terminal disease of chest or abdomen, is worthy of consideration. In an age before modern drugs and anaesthetics this was one of the few solaces available. Even today, there are a few situations for which this deep-acting pain-killer is indicated as, for instance, wounds healed but not without pain.

In spite of the plethora of modern drugs to combat the pain of terminal illness, few are as effective as the greatest anodyne of all time which led the eminent Sydenham to say “. . . if it were expunged from the pharmacopoeia, I would give up the practise of medicine”. ... opium poppy

Paeony

Paeonia lactiflora, Paeonia suffruticosa. German: Paeonie. French: Pivoine. Italian: Peonia. Iranian: Fawania Aod-el-Salib. Indian: Ud salap. Chinese: Bai shae Yae. Parts used: root and root bark.

Constituents. Alkaloids, benzoic acid, asparagin, volatile oil.

Action: antispasmodic, sedative, diuretic, emmenagogue. CNS relaxant, antibacterial, hypotensive, anti- inflammatory, analgesic, liver protector, stimulant to circulatory vessels.

Uses: Old English traditional: epilepsy, chorea. Painful spasm induced by gall or renal stone, whooping cough, children’s convulsions, anal fissure, piles, ulceration of the perineum or coccyx (suppositories, or bathing with strong infusion).

Preparations: Strong infusion: 2oz bruised leaves to 1 pint boiling water; infuse 15 minutes. External use only.

Tincture of the fresh root gathered in spring. 2oz bruised root in 1 pint 45 per cent alcohol. Macerate 8 days, shake daily; filter. Bottle in stoppered amber-coloured bottle. Dose, 10-20 drops thrice daily for the above conditions or when epileptic attack is suspected.

Contra-indications: large doses toxic. For use by medical practitioner only. ... paeony

Interstitial Pulmonary Fibrosis

Scarring of lung tissue mainly involving the alveoli. There are a number of causes, including occupational exposure to dusts and fibrosing alveolitis, which is an autoimmune disorder.... interstitial pulmonary fibrosis

Korsakoff’s Psychosis

See Wernicke– Korsakoff syndrome.... korsakoff’s psychosis

Lobotomy, Prefrontal

Cutting of some of the fibres linking the frontal lobes to the rest of the brain.

This operation was formerly used to treat severe psychiatric disorders; it is very rarely performed now.... lobotomy, prefrontal

Palming

To strengthen the eyes and overcome fatigue. Sit in a comfortable chair. Free the mind of apprehensions. Loosen up. Relax completely. Close the eyes and cover with palms of the hands; leave the nose free. Without undue pressure exclude the light, gazing into the darkness. Support the arms and ‘palm’ for 20 or more minutes. To rub the hands with Aloe Vera is said to heighten its effect.

Palming was initiated by Dr William Bates who, suffering from physical exhaustion and eye strain cupped his eyes in his palms to relax the tension. A few minutes later he felt refreshed and his eyes no longer ached. From this experience he devised the Bates Method to strengthen the eyes. ... palming

Paracelsus

1490-1541. Theophrastus Bombastus Hohenheim. Physician and alchemist. Owed his early education to his father, a physician. Learned the practice of medicine from many sources but lost faith in the orthodox profession of his day. Supported the Doctrine of Signatures, which is really a doctrine of analogies that suggest every herb reveals by its shape, colour and scent the disease it can cure. See: DOCTRINE OF SIGNATURES. The first to introduce into pharmacy the minerals antimony, mercury and sulphur, now known to be inimical to health and which have led the practice of medicine further away from the pure Hippocratic concept. He taught that diseases were specific entities and should be cured by specific remedies. ... paracelsus

Parkinson’s Disease

(PD). Paralysis agitans. First described by James Parkinson, 1817. His description is as apt today as when it appeared in his book “Essay on the Shaking Palsy”. He wrote: “It is characterised by involuntary tremulous motion, with lessened muscular power in parts not in action and even when supported. There is a tendency to bend the trunk forward and to pass from a walking to a running pace. The senses and intellect are uninjured.”

Added to the above are:– muscular rigidity, loss of reflexes, drooling – escape of saliva from the mouth. Muscles of the face are stiff giving a fixed expression, the back presents a bowed posture. The skin is excessively greasy and the patient is unable to express emotional feelings. Loss of blinking. Pin- rolling movement of thumb and forefinger.

Causes: degeneration of groups of nerve cells deep within the brain which causes a lack of neurotransmitting chemical, dopamine. Chemicals such as sulphur used by agriculture, drugs and the food industry are suspected. Researchers have found an increase in the disease in patients born during influenza pandemics.

Treatment. While cure is not possible, a patient may be better able to combat the condition with the help of agents that strengthen the brain and nervous system.

Tea. Equal parts: Valerian, Passion flower, Mistletoe. 1 heaped teaspoon to each cup water; bring to boil; simmer 1 minute; dose: half-1 cup 2-3 times daily.

Gotu Kola tea. (CNS stimulant).

Tablets/capsules. Black Cohosh, Cramp bark, Ginseng, Prickly Ash, Valerian.

Formula. Ginkgo 2; Black Cohosh 1; Motherwort 2; Ginger 1. Mix. Dose. Powders: 500mg (two 00 capsules or one-third teaspoon). Liquid extracts: 1 teaspoon. Tinctures: 1-3 teaspoons in water or honey. Fava Bean Tea.

Case report. Two patients unresponsive to Levodopa treatment reported improvement following meals of fresh broad beans. (Vicia faba) The beans contain levodopa in large amounts. (Parkinson Disease Update Vol 8, No 66, p186, Medical Publications, PO Box 24622-H, Philadelphia, USA) See also: BROAD BEANS. L-DOPA.

Nacuna Pruriens. Appropriate. Essential active constituent: L-dopa. (Medicinal plants and Traditional Medicine in Africa, by Abayomi Sofowora, Pub: John Wiley)

Practitioner. To reduce tremor: Tincture Hyoscyamus BP. To reduce spasm: Tincture Belladonna BP. To arrest drooling: Tincture Stramonium BP.

Diet. It is known that people who work in manganese factories in Chile may develop Parkinson’s disease after the age of 30. Progress of the disease is arrested on leaving the factory. Two items of diet highest in manganese are wheat and liver which should be avoided, carbohydrates in place of wheat taking the form of rice and potatoes.

Supplements. Daily: B-complex, B2, B6, niacin. C 200mg to reduce side-effects of Levodopa. Vitamin E 400iu to possibly reduce rigidity, tremors and loss of balance.

Treatment of severe nerve conditions should be supervised by neurologists and practitioners whose training prepares them to recognise serious illness and to integrate herbal and supplementary intervention safely into the treatment plan.

Antioxidants. Evidence has been advanced showing how nutritional antioxidants, high doses of Vitamin C and E, can retard onset of the disease, delaying the use of Levodopa for an average of 2 and a half years. (Fahn S., High Dose Alpha-tocopherol and ascorbate in Early Parkinson’s Disease – Annals of Neurology, 32-S pp128-132 1992)

For support and advice: The Parkinson’s Disease Society, 22 Upper Woburn Place, London WC1H 0RA, UK. Send SAE. ... parkinson’s disease

Lupus Pernio

Sarcoidosis affecting the skin, in which purple, chilblain-like swellings appear on the nose, cheeks, or ears.... lupus pernio

Middle-ear Effusion, Persistent

See glue ear.... middle-ear effusion, persistent

Mitral Valve Prolapse

A common, slight deformity of the mitral valve, in the left side of the heart, that can produce a degree of mitral incompetence. The prolapse is most common in women and causes a heart murmur. It may be inherited, but the cause is often unknown.Usually, there are no symptoms, and treatment is not needed. Occasionally, the condition may produce chest pain, arrhythmia, or, rarely, heart failure. Often, no treatment is required for mitral valve prolapse, but some people may be treated with beta-blocker drugs, diuretic drugs, antiarrhythmic drugs, or, rarely, heart-valve surgery.... mitral valve prolapse

Molar Pregnancy

A pregnancy in which a tumour develops from the placental tissue and the embryo does not develop normally. A molar pregnancy may be noncancerous (a hydatidiform mole) or may invade the wall of the

uterus (an invasive mole). A molar pregnancy that becomes cancerous is called a choriocarcinoma.

If the dead embryo and placenta are not expelled from the uterus after a miscarriage, the dead tissue is called a carneous mole.... molar pregnancy

Mons Pubis

The rounded swelling over the front of the pubic bone. The mons pubis, which becomes covered with hair at puberty, is formed by a pad of fatty tissue under the skin.... mons pubis

Back Pain

Pain affecting the back, often restricting movement. The pain usually lasts for only a week or so but can recur in some people. Rarely, persistent back pain causes long-term disability.

Back pain is usually caused by minor damage to the ligaments and muscles in the back. The lower back is especially vulnerable to these problems because it supports most of the body’s weight and is under continual stress from movements such as bending, twisting, and stretching. Less commonly, lower back pain may result from an underlying disorder such as a prolapsed intervertebral disc (see disc prolapse) in the spine.

In most cases, back pain can be treated with over-the-counter painkillers (see analgesic drugs) such as aspirin and related drugs, nonsteroidal antiinflammatory drugs, or muscle-relaxant drugs. If the pain persists, a heat pad, a wrapped hot-water bottle or, sometimes, an ice-pack, may provide additional relief. Generally, it is advisable to remain as active as the pain permits. People whose pain worsens or is still too severe to allow normal movement after several days should consult a doctor for medical tests.

Investigations for back pain, such as X-rays, CT scanning, or MRI, sometimes reveal abnormalities, such as disc prolapse, that require surgical treatment and can be treated by a microdiscectomy.

Other treatments for back pain include acupuncture, spinal injection, exercise, or spinal manipulation.... back pain

Behavioural Problems In Children

Behavioural problems range from mild, short-lived periods of unacceptable behaviour, which are common in most children, to more severe problems such as conduct disorders and refusal to go to school. Behavioural problems may occasionally occur in any child; specialist management is called for when the problems become frequent and disrupt school and/or family life. Some behavioural problems can occur whatever the family or home situation. In some cases, however, stressful external events, such as moving home or divorce, may produce periods of problem behaviour.

Behavioural problems that are common in babies and young children include feeding difficulties (see feeding, infant) and sleeping problems, such as waking repeatedly in the night. In toddlers, breath-holding attacks, tantrums, separation anxiety, and head-banging are problems best dealt with by a consistent and appropriate approach. Problems with toilet-training are usually avoided if the training is delayed until the child is physically and emotionally ready.

Between the ages of 4 and 8, behavioural problems such as nail-biting and thumb-sucking, clinginess, nightmares, and bed-wetting (see enuresis) are so common as to be almost normal.

They are best dealt with by a positive approach that concentrates on rewarding good behaviour.

In most cases, the child grows out of the problem, but sometimes medical help may be needed.... behavioural problems in children

Blood Products

Donated blood that is separated into its various components: red cells, white cells, platelets, and plasma (see blood donation). Each blood product has a specific lifespan and use in blood transfusion. Packed red cells (blood with most of the plasma removed) are used to treat patients with some forms of chronic anaemia and babies with haemolytic disease of the newborn. Washed red cells (with white blood cells and/or plasma proteins removed) are used when a person needs repeated transfusions because there is less risk of an allergy to any of the blood components developing.

Platelets may be given in transfusions for people with blood-clotting disorders. Patients who have life-threatening infections may be treated with granulocytes, a type of white blood cell. Fresh frozen plasma is used to correct many types of bleeding disorder because it contains all the clotting factors. Albumin, prepared from the plasma of whole blood, is used mainly to treat shock resulting from severe blood loss until compatible whole blood becomes available. Purified albumin preparations are used to treat nephrotic syndrome and chronic liver disease.

Concentrates of blood clotting factors and are used in the treatment of haemophilia and Christmas disease.

Immunoglobulins (also called antibodies), which are extracted from blood plasma, can be given by injection (see immunoglobulin injection) to protect people who are unable to produce their own antibodies or have already been exposed to an infectious agent, or to provide short-term protection against hepatitis A.

Immunoglobulins are given in large doses to treat certain autoimmune disorders.... blood products

Multiple Personality

A rare disorder in which a person has 2 or more distinct personalities, each of which dominates at different times. The personalities are usually very different from each other.... multiple personality

Multiple Pregnancy

See pregnancy, multiple.... multiple pregnancy

Myofascial Pain Syndrome

See temporomandibular joint syndrome.... myofascial pain syndrome

Nasal Polyp

A growth in the lining of the nose, usually attached by a small stalk.

Most nasal polyps are noncancerous, but they may need to be removed if they cause nasal obstruction.... nasal polyp

Paget’s Disease Of The Nipple

A rare type of breast cancer in which a tumour develops in the nipple.

The disease resembles eczema and can cause itching and a burning feeling.

A non-healing sore may develop.

Without treatment, the tumour may spread into the breast.

Diagnosis is made with a biopsy.... paget’s disease of the nipple

Painful Arc Syndrome

A condition in which pain occurs when the arm is raised between 45 and 160 degrees from the side. The usual cause is an inflamed

tendon or bursa around the shoulder joint being squeezed between the scapula and humerus.

Treatment includes physiotherapy and injection of corticosteroid drugs.... painful arc syndrome

Painkillers

See analgesic drugs.... painkillers

Pain Relief

The treatment of pain, usually with analgesic drugs. Paracetamol, aspirin and codeine are the most widely used drugs in this group. Pain accompanied by inflammation is often alleviated by nonsteroidal anti-inflammatory drugs (NSAIDs). Severe pain may require treatment with opioids, such as morphine.

Other methods of pain relief include massage, ice-packs, poultices, TENS, acupuncture, or hypnosis. Surgery to destroy pain-transmitting nerves (as in a cordotomy) is occasionally performed when other treatments fail.... pain relief

Chest Pain

Pain in the chest, which is often without serious cause, but which may be a symptom of an underlying disorder requiring urgent treatment. The pain may be in the chest wall or in an organ within the chest. The most common causes of pain in the chest wall are a strained muscle or an injury, such as a broken rib. A sharp pain that travels to the front of the chest may be due to pressure on a nerve root attached to the spinal cord as a result of, for example, osteoarthritis of the vertebrae. Pain in the side of the chest may be due to pleurodynia. The viral infection herpes zoster (shingles) may cause severe pain along the course of a nerve in the chest

wall. In Tietze’s syndrome, inflammation at the junctions of the rib cartilages causes pain on the front of the chest wall.

Pain within the chest may be caused by pleurisy, as a result of bronchitis, pneumonia, or, rarely, pulmonary embolism. Cancerous tumours of the lung (see lung cancer; mesothelioma) may cause pain as they grow and press on the pleura and ribs. Acid reflux may lead to heartburn, a burning pain behind the sternum. The common heart disorder angina pectoris causes pain in the centre of the chest that may spread outwards to the throat, jaw, or arms. Myocardial infarction (heart attack) and acute pericarditis both also produce severe pain in the centre of the chest. Mitral valve prolapse may cause sharp chest pain, usually on the left side. Chest pain may also be a result of anxiety and emotional stress (see hyperventilation; panic attack).... chest pain

Cleft Lip And Palate

A split in the upper lip and/or palate that is present at birth. Cleft lip is a vertical, usually off-centre split in the upper lip that may be a small notch or may extend to the nose. The upper gum may also be cleft, and the nose may be crooked. The term

hare lip refers only to a midline cleft lip, which is rare. Cleft palate is a gap that may extend from the back of the palate to behind the teeth and be open to the nasal cavity. Cleft palate is often accompanied by partial deafness and there may be other birth defects.

Surgery to repair a cleft lip may be undertaken in the first few days after birth or at about 3 months.

It improves appearance; after repair, speech defects are rare.

A cleft palate is usually repaired at about 12 months, but further surgery, orthodontic treatment, and speech therapy may be required.... cleft lip and palate

Diabetic Pregnancy

Pregnancy in a woman with pre-existing diabetes mellitus or in a woman who develops diabetes during pregnancy. The latter is known as gestational diabetes. Women with established diabetes mellitus can have a normal pregnancy provided that the diabetes is controlled well. Poor control of blood glucose during the pregnancy may affect the baby’s growth or increase the risk of complications during pregnancy.

Gestational diabetes is usually detected in the second half of pregnancy.

The mother does not produce enough insulin to keep blood glucose levels normal.

True gestational diabetes disappears with the delivery of the baby but is associated with an increased risk of developing type 2 diabetes in later life.... diabetic pregnancy

Disc Prolapse

A common disorder of the spine, in which an intervertebral disc ruptures and part of its pulpy core protrudes. It causes painful and at times disabling pressure on a nerve root or, less commonly, on the spinal cord. The lower back is most commonly affected. A prolapsed disc may sometimes be caused by a sudden strenuous action, but it usually develops gradually as a result of degeneration of the discs with age. If the sciatic nerve root is compressed, it causes sciatica, which may be accompanied by numbness and tingling, and, eventually, weakness in the muscles of the leg. A prolapsed disc in the neck causes neck pain and weakness in the arm and hand.

Symptoms improve with time and analgesic drugs. However, in severe cases, surgical techniques, such as decompression of the spinal canal or removal of the protruding material and repair of the disc, may be necessary.... disc prolapse

Palliative Treatment

Treatment that relieves the symptoms of a disorder but does not cure it.... palliative treatment

Pancreatography

Imaging of the pancreas or its ducts using CT scanning, MRI, ultrasound scanning, X-rays (following injection of a radiopaque contrast medium into the pancreatic ducts during exploratory surgery), or with ERCP.... pancreatography

Par-/para-

Prefixes that may mean beside or beyond, closely resembling or related to, or faulty or abnormal.... par-/para-

Para-aminobenzoic Acid

The active ingredient of many sunscreen preparations. Its abbreviation is.... para-aminobenzoic acid

Drug Poisoning

The harmful effects on the body as a result of an excessive dose of a drug. Accidental poisoning is most common in young children. In adults, it usually occurs in elderly or confused people who are unsure about their treatment and dosage requirements. Accidental poisoning may also occur during drug abuse. Deliberate self-poisoning is usually a cry for help (see suicide; suicide, attempted). The drugs that are most commonly taken in overdose include benzodiazepine drugs and antidepressant drugs. Anyone who has taken a drug overdose and any child who has swallowed tablets that belong to someone else should seek immediate medical advice. It is important to identify the drugs that have been taken. Treatment in hospital may involve washing out the stomach (see lavage, gastric). Charcoal may be given by mouth to reduce the absorption of the drug from the intestine into the bloodstream. To eliminate the drug, urine production may be increased by an intravenous infusion. Antidotes are available only for specific drugs. Such antidotes include naloxone (for morphine) and methionine (for paracetamol).

Drug poisoning may cause drowsiness and breathing difficulty, irregular heartbeat, and, rarely, cardiac arrest, fits, and kidney and liver damage.

Antiarrhythmic drugs are given to treat heartbeat irregularity.

Fits are treated with anticonvulsants.

Blood tests to monitor liver function and careful monitoring of urine output are carried out if the drug is known to damage the liver or kidneys.... drug poisoning

Eardrum, Perforated

Rupture or erosion of the eardrum. Perforation of the eardrum can cause brief, intense pain. There may be slight bleeding, a discharge from the ear (see ear, discharge from), and some reduction in hearing.

Most commonly, perforation occurs as a result of the build-up of pus in the middle ear due to acute otitis media. Perforation may also be associated with cholesteatoma. Another cause is injury, for example from insertion of an object into the ear, a loud noise, barotrauma, or a fracture to the base of the skull.

Diagnosis is confirmed by examination of the ear (see ear, examination of).

Hearing tests may also be performed.

Analgesic drugs may relieve any pain and antibiotic drugs may be prescribed to treat or prevent infection.

Most perforations heal quickly.

If the perforation has failed to heal after 6 months, myringoplasty may be needed.... eardrum, perforated

Examination, Physical

The part of a medical consultation in which the doctor looks, feels, and listens to various parts of the patient’s body to assess the patient’s condition or to gather information to help make a diagnosis.

Most examinations include palpation, by which the doctor examines relevant parts of the body for signs such as swelling, tenderness, or enlargement of organs. In some cases, percussion of the chest, or other parts of the body, may be performed by tapping with the fingers and then listening to the sound produced. Auscultation may be used to listen to blood flow through arteries and sounds made by the heart and lungs. The doctor may take the pulse or blood pressure, examine the eyes and ears, and assess the strength and coordination of the muscles.... examination, physical

Facial Palsy

Weakness of the facial muscles due to inflammation of or damage to the facial nerve. The condition is usually temporary and affects only one side of the face.

Facial palsy is most often due to Bell’s palsy, which occurs for no known reason. Less commonly, facial palsy is associated with herpes zoster affecting the ear and facial nerve. Facial palsy may also result from surgical damage to this nerve or compression of the nerve by a tumour.

Facial palsy usually comes on suddenly. The eyelid and corner of the mouth droop on one side of the face and there may be pain in the ear on that side. The sense of taste may be impaired or sounds may seem to be unnaturally loud.

In many cases, facial palsy clears up without treatment. Pain can be relieved by taking analgesic drugs, and exercising the facial muscles may aid recovery. In some cases, it may be necessary to tape the eyelid shut at bedtime in order to avoid the risk of corneal abrasion. Bell’s palsy may be treated with corticosteroid drugs to reduce inflammation and speed recovery. Re-routing or grafting of nerve tissue may help people with palsies as a result of injury or a tumour.... facial palsy

Henoch–schönlein Purpura

Inflammation of small blood vessels, causing leakage of blood into the skin, joints, kidneys, and intestine. The disease is most common in young children, and may occur after an infection such as a sore throat. The condition may also be due to an abnormal allergic reaction.

The main symptom is a raised purplish rash on the buttocks and backs of the limbs. The joints are swollen and often painful, and colicky abdominal pain may occur. In some cases, there is intestinal bleeding, leading to blood in the faeces. The kidneys may become inflamed, resulting in blood and protein in the urine.

The only treatment usually required is bed rest and analgesic drugs. Complications may arise if kidney inflammation persists. In severe cases, corticosteroid drugs may be given.... henoch–schönlein purpura

Paraffinoma

A tumour-like swelling under the skin caused by prolonged exposure to paraffin. Paraffinomas may form in the lungs if paraffin is inhaled.... paraffinoma

Paralysis, Periodic

A rare, inherited condition that affects young people. Periodic paralysis is characterized by episodes of muscle weakness, which vary in frequency from daily to every few years and last from a few minutes to a few hours. In some cases, there is a drop in the potassium levels in the blood; in others, the levels rise. A carbohydraterich meal may trigger an attack. The condition often clears up without treatment by age 40.... paralysis, periodic

Paramedic

A term for any health-care worker other than a doctor, nurse, or dentist. The term usually refers to ambulance staff who attend accidents or medical emergencies.... paramedic

Parotid Glands

The largest of the 3 pairs of salivary glands.

The parotid glands lie above the angle of the jaw, below and in front of the ear, on each side of the face.... parotid glands

Intercourse, Painful

Pain during sexual intercourse, known medically as dyspareunia, which can affect both men and women. Pain may be superficial (around the external genitals) or deep (within the pelvis).

In men, superficial pain may be due to anatomical abnormalities such as chordee (bowed erection) or phimosis (tight foreskin). Prostatitis may cause a widespread pelvic ache, a burning sensation in the penis, or pain on ejaculation.

Scarring (after childbirth, for example) and lack of vaginal lubrication, especially after the menopause, may cause painful intercourse in women. Psychosexual dysfunction may also cause pain during intercourse. Vaginismus, a condition in which the muscles of the vagina go into spasm, is usually psychological in origin. Deep pain is frequently caused by pelvic disorders (such as fibroids, endometriosis, ectopic pregnancy, or pelvic inflammatory disease due to sexually transmitted infections), disorders of the ovary (such as ovarian cysts), and disorders of the cervix. Other causes are cystitis and urinary tract infections.Treatment is directed at the underlying cause of the pain.

If the discomfort is psychological in origin, special counselling may be needed (see sex therapy).... intercourse, painful

Intraocular Pressure

The pressure within the eye that helps to maintain the shape of the eyeball, due to the balance between the rate of production and removal of aqueous humour. Aqueous humour is continually produced from the ciliary body and exits from the drainage angle (a network of tissue between the iris and cornea). If drainage is impeded, intraocular pressure builds up (a condition known as glaucoma). If the ciliary body is damaged (as a result of prolonged inflammation), ultrasound scanning may be performed to assess the problem. The underlying cause is treated, if possible. If the baby’s growth is slowing, induction of labour or a caesarean section may be necessary. Most babies whose growth was retarded in the uterus gain weight rapidly after delivery. However, if an intrauterine infection or genetic disorder was the cause, poor growth may continue.

less fluid is produced and the eye becomes soft.... intraocular pressure

Kidney, Polycystic

An inherited disorder in which both kidneys are affected by numerous cysts that gradually enlarge until most of the normal kidney tissue is destroyed.

Polycystic kidney disease is distinguished from multiple simple kidney cysts, which occur commonly with age.

There are 2 types of polycystic disease.

The most common usually becomes apparent in middle age, producing abdominal swelling, pain, and blood in the urine.

As the disease progresses, hypertension and kidney failure may result.

The rare type causes enlargement of the kidneys and kidney failure in infants and young children.

There is no effective treatment for preserving kidney function in either type, but symptoms of kidney failure can be treated by dialysis and kidney transplant.... kidney, polycystic

Ovary, Polycystic

A condition, also called Stein–Leventhal syndrome, that is characterized by oligomenorrhea or amenorrhoea (scanty or absent periods), infertility, hirsutism (excessive hairiness), and obesity. Often, there are multiple ovarian cysts. Most women with polycystic ovaries begin menstruation at a normal age, but after a year or two periods become highly irregular and then cease. Hirsutism and obesity occur in about 50 per cent of cases.

The condition results from an imbalance of two gonadotrophin hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH). This hormonal imbalance is associated with raised levels of testosterone and oestrogen.

Treatments include clomifene and oral contraceptives. Polycystic ovaries are often associated with high oestrogen levels in the body, which increase the risk of endometrial cancer (see uterus, cancer of); treatment with progesterone may be recommended for this problem. ... ovary, polycystic

Pancreas, Cancer Of

A cancerous tumour of the exocrine tissue of the pancreas. The cause is unknown, but smoking and a high intake of fats or alcohol may be contributing factors. Symptoms include upper abdominal pain, loss of appetite, weight loss, and jaundice. There may also be indigestion, nausea, vomiting, diarrhoea, and tiredness. In many cases, symptoms do not appear until the cancer has spread to other parts of the body.

Diagnosis usually requires ultrasound scanning, CT scanning or MRI of the upper abdomen, or ERCP.

In early stages, pancreatectomy, radiotherapy and anticancer drugs may provide a cure.

In later stages, little can be done apart from provision of palliative treatment.... pancreas, cancer of

Parotitis

Inflammation of the parotid glands, often due to infection with the mumps virus.... parotitis

Parrot Fever

The common name for psittacosis.... parrot fever

Passive Smoking

Involuntary inhalation of tobacco smoke by people who do not smoke. Passive smoking has been shown to increase the risks of chest and ear infections in children and of tobaccoinduced cancers in adults.... passive smoking

Paternity Testing

The use of blood tests to help decide whether a man is the father of a child.

Blood samples are taken from the child, from the suspected father, and sometimes from the mother.

The samples are tested for blood groups, histocompatibility antigens, and similarities in DNA.

Genetic fingerprinting provides the most decisive result.... paternity testing

Panic Attack

A brief period of acute anxiety, often dominated by an intense fear of dying or losing one’s reason. Attacks are unpredictable at first, but tend to become associated with specific situations, such as a cramped lift.

Symptoms (a sense of breathing difficulty, chest pains, palpitations, feeling light-headed, dizziness, sweating, trembling, and faintness) begin suddenly. Hyperventilation often occurs, causing a pins-and-needles feeling, and feelings of depersonalization and derealization. The attacks end quickly.

Panic attacks are generally a feature of an anxiety disorder, agoraphobia, or other phobias. In some cases, such attacks are part of a somatization disorder or schizophrenia. Behaviour therapy and relaxation exercises may be used in treatment of this condition.... panic attack

Pathology, Cellular

Also called cytopathology, the branch of cytology concerned with the effects of disease on cells.... pathology, cellular

Pathology, Chemical

Another name for clinical biochemistry, the study of abnormalities in the chemistry of body tissues in disease.... pathology, chemical

Pathophysiology

The study of the effects of disease on body functions.... pathophysiology

Peau D’orange

A condition in which the skin has a normal colour but looks like orange peel. The skin’s dimpled appearance is due to fluid retention in the nearby lymph vessels.... peau d’orange

Pelvic Examination

Examination of a woman’s external and internal genitalia.

After examination of the external genitalia, a speculum is inserted into the vagina to allow a clear view of the cervix.

A cervical smear test may be performed.

The doctor inserts 2 fingers into the vagina and, with the other hand, feels the abdomen to evaluate the position and size of the uterus and the ovaries and to detect any tenderness or swelling.... pelvic examination

Pelvic Floor Exercises

A programme of exercises to strengthen the muscles and tighten the ligaments at the base of the abdomen, which form the pelvic floor.

These muscles and ligaments support the uterus, vagina, bladder, urethra, and rectum. Performing the exercises may help to prevent prolapse of the uterus (see uterus, prolapse of) and urinary stress incontinence (see incontinence, urinary). They may also help women who find achieving orgasm difficult.

The pelvic floor muscles are those that tighten when urine flow is stopped midstream. The exercises involve stopping and starting urine flow several times by contracting and relaxing the muscles. Ideally, they should be performed for 5 minutes every hour throughout the day. They can be done standing, sitting, or lying down, by imagining that urine is being passed, contracting and holding the muscles for 10 seconds, and then slowly releasing them, repeating 5–10 times as often as possible.... pelvic floor exercises

Pelvic Infection

An infection in the female reproductive system. Severe or recurrent pelvic infection is referred to as pelvic inflammatory disease (PID). ... pelvic infection

Pelvic Pain

See abdominal pain.... pelvic pain

Penicillin Drugs

A group of antibiotic drugs.

Natural penicillins are derived from the mould PENICILLIUM; others are synthetic preparations.

Penicillins are used to treat many infective conditions, including tonsillitis, bronchitis, bacterial endocarditis, syphilis, and pneumonia.

They are also given to prevent rheumatic fever from recurring.

Common adverse effects of penicillins are an allergic reaction causing a rash, and diarrhoea.... penicillin drugs

Penile Implant

A prosthesis inserted into the penis to help a man suffering from permanent impotence to achieve intercourse.

The various types include a silicone splint inserted in the tissues of the upper surface of the penis, and an inflatable prosthesis that is inflated by squeezing a small bulb in the scrotum.... penile implant

Penile Warts

See warts, genital.... penile warts

Penis, Cancer Of

A rare type of cancerous tumour that is more common in uncircumcised men with poor personal hygiene. Viral infection and smoking have both been shown to be additional risk factors. The tumour usually starts on the glans or on the foreskin as a painless, wart-like lump or a painful ulcer, and develops into a cauliflowerlike mass. The growth usually spreads slowly, but in some cases it can spread to the lymph nodes in the groin within a few months.

Diagnosis is made by a biopsy.

If the tumour is detected early, radiotherapy is usually successful.

Otherwise, removal of part or all of the penis may be necessary.... penis, cancer of

Pentazocine

An opioid analgesic drug used to relieve moderate or severe pain caused by injury, surgery, cancer, or childbirth. It is rarely used because of its adverse affects, which include dizziness, drowsiness, nausea, vomiting, and, rarely, hallucinations. Drug dependence may develop if high doses are taken for prolonged periods.... pentazocine

Perinatology

A branch of obstetrics and paediatrics concerned with the study and care of the mother and baby during pregnancy and just after birth.... perinatology

Period, Menstrual

See menstruation.... period, menstrual

Periodontics

The branch of dentistry concerned with periodontal disease.... periodontics

Period Pain

See dysmenorrhoea.... period pain

Permanent Teeth

The 2nd teeth, which usually start to replace the primary teeth at about the age of 6. There are 32 permanent teeth: 16 in each jaw. Each set of 16 consists of 4 incisors, 2 canines, 4 premolars and 6 molars. (See also eruption of teeth.)... permanent teeth

Peroneal Muscular Atrophy

A rare, inherited disorder characterized by muscle wasting in the feet and calves and then in the hands and forearms.

The condition, also known as Charcot–Marie– Tooth disease, is caused by degeneration of some peripheral nerves.

It is more common in boys, and usually appears in late childhood or adolescence.

Muscle wasting stops halfway up the arms and legs, making them look like inverted bottles; sensation may be lost.

There is no treatment, but the sufferer rarely becomes totally incapacitated because the disease usually progresses very slowly.

Life expectancy is normal.... peroneal muscular atrophy

Personality Disorders

A group of conditions characterized by a failure to learn from experience or to adapt appropriately to changes, resulting in distress and impairment of social functioning. Personality disorders are ways of behaving that may become especially obvious during periods of stress. They are usually first recognizable in adolescence and continue throughout life, often leading to depression or anxiety.

Specific types of personality disorders are divided into 3 groups but there is often overlap. The 1st group is characterized by eccentric behaviour. Paranoid people show suspiciousness and mistrust of others, schizoid people are cold emotionally, and schizotypal personalities have behaviour oddities similar to those of schizophrenia, but less severe.In the 2nd group, behaviour tends to be dramatic. Histrionic people are excitable and constantly crave stimulation, narcissists have an exaggerated sense of their own importance (see narcissism), and people with antisocial personality disorder fail to conform to accepted social standards of behaviour.

People in the 3rd group show anxiety and fear. Dependent personalities lack the self-confidence to function independently (see dependence). Those with compulsive personalities are rigid in their habits (see obsessive–compulsive disorder), and passive-aggressive people resist demands from others.

Treatment is usually counselling, psychotherapy, and behaviour therapy.... personality disorders

Personality Tests

Questionnaires designed to define various personality traits or types. Tests may be designed to detect psychiatric symptoms, underlying personality traits, how outgoing or reserved a person is, and predisposition to developing neurotic illness.... personality tests

Perthes’ Disease

Inflammation of an epiphysis of the head of the femur.

The disease is a type of osteochondritis juvenilis, thought to be due to disrupted blood supply to the bone.

The condition is most common in boys aged 5–10, and usually affects 1 hip.

Symptoms include pain in the thigh and groin, and a limp on the affected side.

Diagnosis is made with X-rays.

Treatment may be rest for a few weeks, followed by splinting of the hip, or surgery.

The disease usually clears up by itself within 3 years, but the hip may be permanently deformed.... perthes’ disease

Perversion

See deviation, sexual.... perversion

Petroleum Jelly

A greasy substance obtained from petroleum, also known as petrolatum or soft paraffin. The jelly is commonly used as an ointment base, a protective dressing, and an emollient.... petroleum jelly

Peutz–jeghers Syndrome

A very rare, inherited condition in which polyps occur in the gastrointestinal tract and small, flat, brown spots appear on the lips and in the mouth. Occasionally the polyps bleed, or cause abdominal pain or intussusception. Tests include barium X-ray examination and endoscopy. Bleeding polyps may be removed.... peutz–jeghers syndrome

Peyote

A cactus plant found in northern Mexico and the southwest of the. Its dried blossoms are used to prepare the hallucinogenic drug mescaline.... peyote

Pharyngeal Diverticulum

An alternative term for a pharyngeal pouch.... pharyngeal diverticulum

Pharynx, Cancer Of

A cancerous tumour of the pharynx. Pharyngeal cancer usually develops in the mucous membrane lining. In the West, almost all cases of pharyngeal cancer are related to smoking and to drinking alcohol. The incidence rises with age, and the disorder is more common in men.

Cancerous tumours of the oropharynx (the middle section of the pharynx) usually cause difficulty swallowing, often with a sore throat and earache. Bloodstained sputum may be coughed up. Sometimes there is only the feeling of a lump in the throat or a visible enlarged lymph node in the neck. Cancer of the laryngopharynx (the lowermost part of the pharynx) initially causes a sensation of incomplete swallowing, then a muffled voice, hoarseness, and increased difficulty in swallowing. Tumours of the nasopharynx have different causes.Diagnosis of cancer of the pharynx is made by biopsy, often in conjunction with laryngoscopy, bronchoscopy, or oesophagoscopy.

The growth may be removed surgically or treated with radiotherapy.

Anticancer drugs may also be given.... pharynx, cancer of

Phencyclidine

A drug of abuse, commonly known as angel dust or.... phencyclidine

Phenothiazine Drugs

A group of drugs used to treat psychotic illnesses (see antipsychotic drugs) and to relieve severe nausea and vomiting (see antiemetic drugs).

The group includes chlorpromazine, fluphenazine, and perphenazine.... phenothiazine drugs

Phenylbutazone

A nonsteroidal antiinflammatory drug (NSAID) used to relieve the symptoms of ankylosing spondylitis. Phenylbutazone may cause nausea, fluid retention, rash, and peptic ulcer. It may also increase the risk of blood disorders. It is prescribed only under hospital supervision, when other drugs are ineffective.... phenylbutazone

Pheromone

A substance with a particular odour that, when released in minute quantities by an animal, affects the behaviour or development of other individuals of the same species.... pheromone

Physical Medicine And Rehabilitation

A branch of medicine concerned with caring for patients who have become disabled through injury or illness.... physical medicine and rehabilitation

Phyto-

A prefix meaning of plant origin.... phyto-

Phyto-oestrogens

Oestrogens that occur naturally in plants.... phyto-oestrogens

Pickwickian Syndrome

An unusual disorder characterized by extreme obesity, shallow breathing, and sleep apnoea.

The cause is unclear.

Symptoms usually improve with weight loss.... pickwickian syndrome

Pigeon Toes

A minor abnormality in which the leg or foot is rotated, forcing the foot and toes to point inwards.

The condition is common in toddlers.... pigeon toes

Pill, Contraceptive

See oral contraceptives.... pill, contraceptive

Pinworm Infestation

An alternative name for threadworm infestation.... pinworm infestation

Pituitary Tumours

Growths in the pituitary gland. Pituitary tumours are rare, and mostly noncancerous, but tumour enlargement can put pressure on the optic nerves, causing visual defects.

The causes of pituitary tumours are unknown. They may lead to inadequate hormone production, causing problems such as cessation of menstrual periods or reduced sperm production. They may also cause the gland to produce excess hormone. Overproduction of growth hormone causes gigantism or acromegaly; too much thyroid-stimulating hormone (TSH) can lead to hyperthyroidism. Investigations include blood tests, X-rays, MRI of the pituitary, and usually also vision tests. Treatment may be by surgical removal of the tumour, radiotherapy, hormone replacement, or a combination of these techniques. The drug bromocriptine may be used; it can reduce production of certain hormones and shrink some tumours.... pituitary tumours

Pityriasis Alba

A common skin condition of childhood and adolescence.

Irregular, fine, scaly, pale patches appear on the face.

Caused by mild eczema, it usually clears up with emollients.... pityriasis alba

Plaque, Dental

A rough, sticky coating on the teeth consisting of saliva, bacteria, and food debris.

It is the chief cause of tooth decay (see caries, dental) and gingivitis, and forms the basis of a hard deposit (see calculus, dental).

Some of the microorganisms in plaque, particularly STREPTOCOCCUS MUTANS, break down sugar in the remains of carbohydrate food that sticks to the mucus, creating an acid that can erode tooth enamel.... plaque, dental

Plasma Proteins

Proteins present in blood plasma, including albumin, blood clotting proteins, and immunoglobulins.... plasma proteins

Plasminogen Activator

See tissue plasminogen activator.... plasminogen activator

Plaster Cast

See cast.... plaster cast

Play Therapy

A method used in the psychoanalysis of young children, based on the principle that all play has some symbolic significance. Watching a child at play helps a therapist diagnose the source of the child’s problems; the child can then be helped to “act out” thoughts and feelings that are causing anxiety.... play therapy

Pityriasis Rosea

A common, mild skin disorder in which a rash of flat, scaly-edged, pink spots or patches appears on the trunk and upper arms. It is not contagious and mainly affects children and young adults. Its cause is unknown. The rash lasts for 4–8 weeks, may cause itching, and usually clears up without treatment. Calamine lotion or antihistamine drugs may relieve any itching. pityriasis versicolor A common skin condition in which patches of white, brown, or salmon-coloured flaking skin appear on the trunk and neck. Also known as tinea versicolor, it is caused by a fungus that exists on most people’s skin. Treatment is with antifungal drugs. pivampicillin See penicillin drugs. pivmecillinam See penicillin drugs. pizotifen An antihistamine drug used to prevent migraine in people with frequent, disabling attacks. Adverse effects can include nausea, dizziness, drowsiness, dry mouth, and muscle pains.

Prolonged use may cause weight gain.... pityriasis rosea

Plants, Poisonous

Several species of plant, including foxglove, holly, deadly nightshade, and laburnum, are poisonous. Nettles, hogweed, poison ivy, and primula cause skin reactions, including rash and itching, on contact. Young children are the most commonly affected. Symptoms of poisoning vary according to the plant but may include abdominal pain, vomiting, flushing, breathing difficulties, delirium, and coma and require urgent medical advice. Skin reactions can be treated by application of alcohol or calamine lotion; corticosteroid drugs may be prescribed for severe reactions. Poisoning usually requires gastric lavage. Fatal poisoning is rare. (See also mushroom poisoning.)... plants, poisonous

Pleural Effusion

An accumulation of fluid between the layers of the pleura, making breathing difficult. Pleural effusion may be caused by pneumonia, tuberculosis, heart failure, cancer, pulmonary embolism, or mesothelioma.

Diagnosis is confirmed by chest X-ray.

Some fluid may be removed with a needle and syringe and examined to find the cause.

A biopsy of the pleura may also be needed.

The underlying cause is treated and fluid may be drained off to relieve breathing problems.... pleural effusion

Plummer–vinson Syndrome

Difficulty in swallowing due to webs of tissue forming across the upper oesophagus. The syndrome often occurs with severe iron-deficiency anaemia and affects middle-aged women.... plummer–vinson syndrome

Plutonium

A radioactive metallic element which occurs naturally only in uranium ores; it is produced artificially in breeder reactors.... plutonium

Pocket, Gingival

See periodontitis.... pocket, gingival

Polio

An abbreviation for poliomyelitis.... polio

Pollution

Contamination of the environment by poisons, radioactive substances, microorganisms, or other wastes.... pollution

Polycystic Kidney

See kidney, polycystic.... polycystic kidney

Polymyxins

A group of antibiotic drugs derived from the bacterium BACILLUS POLYMYXA. Polymyxins, which include colistin, are commonly given to treat eye, ear, and skin infections.... polymyxins

Poisoning

Poisons may be swallowed, inhaled, absorbed through skin, or injected under the skin (as with an insect sting).

Poisons may also originate in the body, as when bacteria produce endotoxins, or when metabolic disorders produce poisonous substances or allow them to build up.

Poisoning may be acute (a large amount of poison over a short time) or chronic (gradual accumulation of poison that is not eliminated quickly).

Unintentional poisoning occurs mainly in young children.

Adults may be poisoned by mistaking the dosage of a prescribed drug (see drug poisoning), by taking very high doses of vitamin or mineral supplements, by exposure to poisonous substances in industry, or by drug abuse.

Poisoning may also be a deliberate attempt to commit suicide.... poisoning

Polyposis, Familial

A rare, inherited disorder, also known as polyposis coli, in which many polyps are present throughout the gut, but mainly in the colon. If not treated, cancer of the colon (see colon, cancer of) is almost certain to develop. The polyps may appear from age 10. They may cause bleeding and diarrhoea; however, there are often no symptoms until cancer has developed. The polyps are detected by colonoscopy.

Since there is a 50 per cent chance that children of an affected person will inherit the disease, medical surveillance is necessary from around the age of 12.

Individual polyps may be cauterized (see cauterization).

The high risk of developing cancer often means that a colectomy and an ileostomy are performed.... polyposis, familial

Polyunsaturated Fats

Fats (see fats and oils) with with relatively few hydrogen atoms in their chemical structure.

Polyunsaturated fats tend to protect against cardiovascular disease.... polyunsaturated fats

Posseting

A term for the regurgitation of small quantities of milk by infants after they have been fed.... posseting

Postherpetic Neuralgia

Burning pain caused by nerve irritation that occurs at the site of a previous attack of herpes zoster (shingles).

See neuralgia.... postherpetic neuralgia

Postmaturity

A condition in which a pregnancy persists for longer than 42 weeks; the average length of a normal pregnancy is 40 weeks (see gestation). Postmaturity may be associated with a family tendency to prolonged pregnancy, or it may be a sign that the baby is unable to descend properly (see engagement). The risk of fetal death increases after 42 weeks because the placenta becomes less efficient. Postmature infants tend to have dry skin and may be more susceptible to infection.... postmaturity

Postmortem Examination

An alternative term for an autopsy.... postmortem examination

Postmyocardial Infarction Syndrome

Another name for Dressler’s syndrome.... postmyocardial infarction syndrome

Postnasal Drip

A watery or sticky discharge from the back of the nose into the nasopharynx.

The fluid may cause a cough, hoarseness, or the feeling of a foreign body.

The usual cause is rhinitis.... postnasal drip

Postnatal Care

Care of the mother after childbirth until about 6 weeks later.... postnatal care

Postpartum Depression

See postnatal depression.... postpartum depression

Posture

The relative position of different parts of the body at rest or during movement.

Good posture consists of balancing the body weight around the body’s centre of gravity in the lower spine and pelvis.

Maintaining good posture helps prevent neck pain and back pain.... posture

Potassium Citrate

A substance used to relieve discomfort in mild urinary tract infections by making the urine less acid.... potassium citrate

Potency

The ability of a man to perform sexual intercourse; or the ability of a drug to cause desired effects.... potency

Pott’s Fracture

A combined fracture and dislocation of the ankle caused by excessive or violent twisting. The fibula breaks just above the ankle; in addition, the tibia breaks or the ligaments tear, resulting in dislocation.... pott’s fracture

Predisposing Factors

Factors that lead to increased susceptibility to a disease.... predisposing factors

Pregnancy, False

An uncommon psychological disorder, medically known as pseudocyesis, in which a woman has physical signs of pregnancy, including morning sickness, amenorrhoea (absence of periods), enlarged breasts, and abdominal swelling, but is not pregnant. The woman is convinced that she is pregnant. Treatment for false pregnancy

may involve counselling or psychotherapy. (See also conversion disorder.)... pregnancy, false

Pregnancy, Multiple

The presence of more than 1 fetus in the uterus. Multiple pregnancy can occur if 2 or more ova (eggs) are fertilized at the same time, or if a single fertilized egg divides early in development.

Twins occur in about 1 in 80 pregnancies, triplets in about 1 in 8,000, and quadruplets in about 1 in 73,000.

Multiple pregnancies are more common in women who are treated with fertility drugs or if a number of fertilized ova are implanted during in vitro fertilization.... pregnancy, multiple

Pregnancy, Drugs In

Certain drugs taken during pregnancy may pass to the fetus through the placenta or interfere with fetal development. This may lead to birth defects. Although relatively few drugs have been proved to cause harm to a developing baby, no drug should be considered completely safe, especially during early pregnancy. For this reason, pregnant women should seek advice from their doctor or pharmacist before taking any drug, including over-thecounter preparations.

Problems may also be caused in a developing baby if a pregnant woman drinks alcohol, smokes (see tobaccosmoking), or takes drugs of abuse. The babies of women who use heroin during pregnancy tend to have a low birthweight and a higher death rate than normal during the first few weeks of life. Babies of women who abuse drugs intravenously are at high risk of HIV infection.... pregnancy, drugs in

Prematurity

Birth of a baby before 37 weeks’ gestation. The premature infant may not be sufficiently developed to cope with independent life and needs special care. About 5–10 per cent of babies are born prematurely.

Some 40 per cent of premature deliveries occur for no known reason. The remainder are due to conditions such as pre-eclampsia, hypertension, diabetes mellitus, long-standing kidney disease, and heart disease. Other causes are antepartum haemorrhage, intrauterine infection, or premature rupture of membranes. A common cause is multiple pregnancy (see pregnancy, multiple).

A premature infant is smaller than a full-term baby, lacks subcutaneous fat, is covered with downy hair (lanugo), and has very thin skin. The baby’s internal organs are also immature. The major complication is respiratory distress syndrome. There is increased risk of brain haemorrhage, jaundice, and hypoglycaemia. The baby has a limited ability to suck and maintain body temperature, and is prone to infection. The earlier a baby is born, the more likely it is to have such problems.

Premature infants are usually nursed in a special baby unit that provides intensive care. The baby is placed in an incubator, and may have artificial ventilation to assist breathing, artificial feeding through a stomach tube or into a vein, and treatment with antibiotic drugs and iron and vitamin supplements. With modern techniques, some infants survive even if they are born as early as 24 weeks’ gestation.... prematurity

Prenatal

The period of pregnancy before childbirth.... prenatal

Prescription-only Medicine

Drugs and medicines that are not available over the counter and can only be obtained by prescription.

Prescription-only medicines are those whose safe use is difficult to ensure without medical supervision.... prescription-only medicine

Preservative

A substance that inhibits growth of bacteria, yeasts, and moulds and so protects foods from putrefying and fermenting. Examples include sulphur dioxide, benzoic acid, salt, sugar, and nitrites. (See also food additives.)... preservative

Pressure Points

Places on the body where arteries lie near the surface and pressure can be applied by hand to limit severe arterial bleeding (in which bright red blood is pumped out in regular spurts with the heartbeat). Major pressure points of the body include the brachial pressure point in the middle part of the upper arm and the carotid pressure point at the side of the neck, below the jaw.... pressure points

Primary

A term applied to a disease that has originated within the organ or tissue affected, and is not derived from any other cause or source. The term primary is also applied to the 1st of several diseases to affect a tissue or organ in turn. Primary is also used to mean “of unknown cause”.... primary

Prinzmetal’s Angina

See variant angina.... prinzmetal’s angina

Probiotic Bacteria

Species of microorganisms that inhabit the digestive tract, guarding it against harmful bacteria, yeasts, and viruses.... probiotic bacteria

Procainamide

An antiarrhythmic drug that is used to treat certain types of tachycardia.

Procainamide may cause nausea, vomiting, loss of appetite, and, rarely, confusion.

Prolonged treatment may induce lupus erythematosus.... procainamide

Proctalgia Fugax

A severe cramping pain in the rectum unconnected with any disease. It may be due to muscle spasm. The pain is of short duration and subsides without treatment.... proctalgia fugax

Proctoscopy

Examination of the anus and rectum with a proctoscope (a rigid viewing instrument).... proctoscopy

Progesterone Hormone

A female sex hormone essential for the functioning of the female reproductive system.

Progesterone is made in the ovaries, and small amounts are produced by the adrenal glands and testes.

During the menstrual cycle, changing progesterone levels cause thickening of the endometrium and menstruation.

If pregnancy occurs, progesterone is produced by the placenta; a fall in its level helps to initiate labour.

Progesterone also causes increased fat deposition and increased sebum production by glands in the skin.... progesterone hormone

Progestogen Drugs

A group of drugs similar to progesterone hormone. The drugs are used in oral contraceptives, are prescribed to treat menstrual problems (see menstruation, disorders of), and are included in hormone replacement therapy (HRT). Progestogen drugs are also used to treat premenstrual syndrome, endometriosis, and hypogonadism, and are sometimes used as anticancer drugs. Adverse effects include weight gain, oedema, headache, dizziness, rash, irregular periods, breast tenderness, and ovarian cysts.... progestogen drugs

Progressive

A term used to describe a condition that becomes more severe and/or extensive over time.... progressive

Progressive Muscular Atrophy

A type of motor neuron disease in which the muscles of the hands, arms, and legs become weak and wasted and twitch involuntarily. The condition eventually spreads to other muscles.... progressive muscular atrophy

Proprietary

A term for a drug patented for production by one company.... proprietary

Proprioception

The body’s internal system for collecting information about its position and the state of contraction of its muscles.

Information from proprioceptors (sensory nerve endings in the muscles, tendons, joints, and the inner ear) passes to the spinal cord and the brain.

The information is used to make adjustments so that posture and balance are maintained.... proprioception

Prostaglandin Drugs

Synthetically produced prostaglandins.

Dinoprostone is used with oxytocin for induction of labour.

Gemeprost softens and helps to dilate the cervix prior to inducing an abortion.

Alprostadil is used to treat newborn infants awaiting surgery for some congenital heart diseases.... prostaglandin drugs

Prostate, Cancer Of

A cancerous growth in the prostate gland, of unknown cause. One of the most common cancers in men, it mainly occurs in elderly men.

An enlarged prostate (see prostate, enlarged) may cause symptoms including difficulty in starting to pass urine, poor urine flow, and increased frequency of urination. Urine flow may eventually cease altogether. When there are no urinary symptoms, the first sign may be pain in the bones from secondary cancers. Screening tests detect blood levels of a protein called prostate specific antigen;

if above a certain level, it may indicate prostate cancer.

Rectal examination allows a doctor to assess the size and hardness of the gland.

Ultrasound scanning and a biopsy confirm the diagnosis.

Blood tests and a bone scan (see radionuclide scanning) may also be done.

In an elderly man with a small prostate cancer that has not spread, no treatment may be recommended.

For younger men, prostatectomy or radiotherapy may be performed.

Widespread disease is usually controllable for some years with orchidectomy or drugs.... prostate, cancer of

Prostate, Enlarged

An increase in the size of the inner zone of the prostate gland, also known as benign prostatic hypertrophy. It is most common in men over 50. The cause is unknown. The enlarging prostate compresses and distorts the urethra, impeding the flow of urine. Eventually the bladder is unable to expel all the urine (see urine retention) and becomes distended, causing abdominal swelling. There may also be incontinence and frequency of urination (see urination, frequent).

Prostate enlargement is detected by a rectal examination.

Tests may include a blood test, ultrasound scanning, urography, and a recording of the strength of urine flow.

Mild cases do not require treatment, but more severe ones usually require prostatectomy.

Alternatively, drug treatment with alpha-blocker drugs or androgen drugs may be given.... prostate, enlarged

Prosthetics, Dental

The branch of dentistry concerned with the replacement of missing teeth and their supporting structures. It includes dentures, overdentures (semipermanent fittings over existing teeth), crowns (see crown, dental), and bridges (see bridge, dental).

protease inhibitors A type of antiviral drug used to delay the progression of HIV infection (see AIDS).... prosthetics, dental

Proteins

Large molecules consisting of hundreds or thousands of amino acids linked into long chains. Proteins may also contain sugars (glycoproteins) and lipids (lipoproteins). There are 2 main types of proteins. Fibrous proteins are insoluble and form the structural basis of many body tissues. Globular proteins are soluble and include all enzymes, many hormones, and some blood proteins, such as haemoglobin.... proteins

Protein Synthesis

The formation of protein molecules through the joining of amino acids.... protein synthesis

Pruritus Ani

Itching of the anus. Causes may include an anal fissure, haemorrhoids, or threadworm infestation.... pruritus ani

Pseud-/pseudo-

Prefixes meaning false.... pseud-/pseudo-

Pseudoephedrine

A decongestant drug used to relieve nasal congestion.

High doses may cause anxiety, nausea, and dizziness.

Occasionally, hypertension, headache, and palpitations occur.... pseudoephedrine

Pseudoepidemic

An outbreak of an illness in a community or in an institution that is thought to be due to a form of hysteria. Typical symptoms are headache and a general feeling of sickness.... pseudoepidemic

Psilocybin

An alkaloid present in some mushrooms.

It is a hallucinogenic drug with properties similar to those of LSD.... psilocybin

Psoas Muscle

A muscle that bends the hip upwards towards the chest.

There are 2 parts: psoas major and psoas minor.

Psoas major acts to flex the hip and rotate the thigh inwards.

Psoas minor bends the spine down to the pelvis.... psoas muscle

Psoralen Drugs

Drugs containing chemicals called psoralens, which occur in some plants and are present in some perfumes.

When absorbed into the skin, psoralens react with ultraviolet light to cause skin darkening or inflammation.

Psoralen drugs may be used in conjunction with ultraviolet light (a combination called PUVA) to treat psoriasis and vitiligo.

Overexposure to ultraviolet light during treatment, or to too high a dose of a psoralen drug, may cause redness and blistering of the skin.

Psoralens in perfumes may cause photosensitivity.... psoralen drugs

Psychoanalytic Theory

A system of ideas developed by Sigmund Freud that explains personality and behaviour in terms of unconscious wishes and conflicts. The main emphasis was on sexuality. Freud believed that a child passes through 3 stages in the first 18 months of life: oral, anal, and genital. After this, the child develops a sexual attraction to the parent of the opposite sex and wants to eliminate the other parent (Oedipus complex). Sexual feelings become latent around age 5 but reemerge at puberty. Psychological problems may develop if fixation occurs at a primitive stage. Modern psychoanalysis has progressed from these ideas and is generally based on the observation that most emotional problems are caused by childhood experiences. Psychoanalysis attempts to free the individual from the past, helping him or her to become a real person in the present. Psychoanalytic theory is decreasing in influence.... psychoanalytic theory

Psychometry

The measurement of psychological functions using intelligence tests, personality tests, and tests for specific aptitudes, such as memory, logic, concentration, and speed of response.... psychometry

Psychosexual Disorders

A range of disorders that are related to sexual function. Psychosexual disorders include transsexualism, psychosexual dysfunction, and sexual deviation.... psychosexual disorders

Psychosexual Dysfunction

A disorder in which there is interference with the sexual response for no physical cause.... psychosexual dysfunction

Psychotropic Drugs

Drugs that have an effect on the mind, including hallucinogenic drugs, sedative drugs, sleeping drugs, tranquillizer drugs, and antipsychotic drugs.... psychotropic drugs

Pubic Bone

The front part of the fused bones that form the pelvis.... pubic bone

Pubic Lice

Small, wingless insects (PHTHIRUS PUBIS) that live in the pubic hair and feed on blood. Also called crab lice or crabs, they are usually spread by sexual contact. A louse has a flattened body, up to 2 mm across. Female lice lay eggs (nits) on the hair, where they hatch about 8 days later. On men, the lice may also be found in hair around the anus, on the legs, on the trunk, and even in facial hair. The bites sometimes cause itching. Children can become infested by transmission from parents, and the lice may live on the eyelids. An insecticide lotion kills the lice and eggs.... pubic lice

Pudenda

A term that refers to the external genitalia.... pudenda

Pudendal Block

A type of nerve block used to provide pain relief for a forceps delivery.

A local anaesthetic (see anaesthesia, local) is injected into either side of the vagina near the pudendal nerve.... pudendal block

Pulmonary Incompetence

A rare defect of the pulmonary valve at the exit of the heart’s right ventricle. The valve fails to close properly, allowing blood to leak back into the heart. The cause is usually rheumatic fever, endocarditis, or severe pulmonary hypertension.... pulmonary incompetence

Pulp, Dental

The soft tissue containing blood vessels and nerves in the middle of each tooth (see teeth).... pulp, dental

Pump, Infusion

A machine that is used for the administration of a continuous, controlled amount of a drug or other fluid. The fluid is delivered through a needle that is inserted into a vein or under the skin.... pump, infusion

Pump, Insulin

A type of infusion pump (see pump, infusion) used to administer a continuous dose of insulin to some patients with diabetes mellitus.

The rate of flow is adjusted so that the level of blood glucose (sugar) is constant.... pump, insulin

Pulmonary Disease, Chronic Obstructive

A combination of chronic bronchitis and emphysema, in which there is persistent disruption of air flow into or out of the lungs. Patients are sometimes described as either pink puffers or blue bloaters, depending on their condition. Pink puffers maintain adequate oxygen in their bloodstream through an increase in their breathing rate, and remain “pink” despite damage to the lungs. However, they suffer from almost constant shortness of breath. Blue bloaters are cyanotic (have a bluish discoloration of the skin and mucous membranes) because of obesity, and sometimes oedema, mainly due to heart failure resulting from the lung damage.... pulmonary disease, chronic obstructive

Punch-drunk

A condition that is characterized by slurred speech, impaired concentration, and slowed thought processes.

It is caused by brain damage from several episodes of brief loss of consciousness due to head injury.... punch-drunk

Pyrexia Of Uncertain Origin

Persistent fever with no apparent cause. The cause is usually an illness that is difficult to diagnose or a common disease that presents in an unusual way. These illnesses include various viral infections; tuberculosis; cancer, particularly lymphoma; and collagen diseases, such as systemic lupus erythematosus and temporal arteritis. Another possible cause is a drug reaction.... pyrexia of uncertain origin

Raynaud’s Phenomenon

A circulatory disorder affecting the fingers and toes that shares the mechanism, symptoms, and signs of Raynaud’s disease but results from a known underlying disorder.

Possible causes include arterial diseases, such as atherosclerosis; connective tissue diseases, such as rheumatoid arthritis; and various drugs, such as beta-blocker drugs.

The disorder is an occupational disorder of people who use pneumatic drills, chain saws, or vibrating machinery; it is sometimes seen in typists, pianists, and others whose fingers suffer repeated trauma.

Treatment is the same as for Raynaud’s disease, along with treatment of the underlying disorder.... raynaud’s phenomenon

Reflex, Primitive

An automatic movement in response to a stimulus that is present in newborn infants but disappears during the first few months after birth. Primitive reflexes are believed to represent actions that were important in earlier stages of human evolution. They include the grasp reflex when something is placed in the hand and the rooting reflex, which enables a baby to find the nipple. The rooting reflex can be evoked by touching the baby’s cheek with the fingertip. These reflexes are tested after birth to give an indication of the condition of the nervous system.... reflex, primitive

Retrosternal Pain

Pain in the central region of the chest, behind the sternum. Causes include irritation of the oesophagus, angina pectoris, or myocardial infarction. (See also chest pain.)... retrosternal pain

Schizoid Personality Disorder

Inability to relate socially to other people. People with this trait, which is apparent from childhood, are often described as “loners” and have few, if any, friends. They are eccentric, seem to lack concern for others, and are apparently detached from normal day-to-day activities.... schizoid personality disorder

Senile Purpura

A skin condition in which areas of the skin develop a purplish or reddish-brown appearance due to bleeding of small blood vessels underneath.

Senile purpura is a disease of middle to old age and is more common in women.... senile purpura

Sexual Problems

Any difficulty associated with sexual performance or behaviour. Sexual problems are often psychological in origin (see psychosexual dysfunction). Sex therapy may help such problems. Some sexual problems are due to physical disease, such as a disorder affecting blood flow or a hormonal dysfunction. A disorder of the genitals may result in pain during intercourse (see intercourse, painful). Such problems are addressed by treating the cause, where possible.... sexual problems

Shellfish Poisoning

See food poisoning.... shellfish poisoning

Sight, Partial

Loss of vision short of total blindness. Partial sight may involve loss of visual acuity and/or visual field.... sight, partial

Skin Patch

See transdermal patch.... skin patch

Skin Peeling, Chemical

A cosmetic operation in which the outer layers of the skin are peeled away by the application of a caustic paste in order to remove freckles, acne scars, delicate wrinkles, or other skin blemishes.... skin peeling, chemical

Sodium Picosulfate

A stimulant laxative drug used to treat constipation and to empty the bowel prior to procedures such as X-ray, endoscopy, and surgery on the intestines. Side effects may include abdominal cramps and diarrhoea. The drug should be avoided in cases of intestinal obstruction.... sodium picosulfate

Split Personality

A common term for multiple personality.

It is also used, incorrectly, to describe schizophrenia.... split personality

Stomach Pump

See lavage, gastric.... stomach pump

Strychnine Poisoning

Strychnine is a poisonous chemical found in the seeds of Strychnos species (tropical trees and shrubs). Its main use is as an ingredient in some rodent poisons; most cases of strychnine poisoning occur in children who accidentally eat such poisons.

Symptoms begin soon after ingestion and include restlessness, stiffness of the face and neck, increased sensitivity of hearing, taste, and smell, and photosensitivity, followed by alternating episodes of seizures and floppiness. Death may occur from respiratory arrest.

The victim is given intravenous injections of a tranquillizer or a barbiturate, with a muscle-relaxant drug if needed.

Breathing may be maintained by a ventilator.

With prompt treatment, recovery usually occurs in about 24 hours.... strychnine poisoning

Termination Of Pregnancy

See abortion, induced.... termination of pregnancy

Testis, Pain In The

Pain in a testis may be caused by mild injury, a tear in the wall of the testis due to a direct blow, orchitis, epididymo-orchitis, and torsion of the testis (see testis, torsion of). Sometimes, no cause is found and the pain disappears without treatment. If the wall of the testis is torn, an operation to repair it may be needed. ... testis, pain in the

Tissue-plasminogen Activator

A substance produced by body tissues that prevents abnormal blood clotting. Also called , it is produced by the inner lining of blood vessels. can be prepared artificially for use as a thrombolytic drug, which is called alteplase. This is used in the treatment of myocardial infarction, severe angina pectoris, and arterial embolism, including pulmonary embolism. Possible side effects include bleeding or the formation of a haematoma at the injection site and an allergic reaction. (See also fibrinolysis.)... tissue-plasminogen activator

Toadstool Poisoning

See mushroom poisoning.... toadstool poisoning

Toxaemia Of Pregnancy

See preeclampsia.... toxaemia of pregnancy

Transdermal Patch

A method of administering a drug through the skin. The drug is released from the patch over a period of time and is absorbed by the skin.... transdermal patch

Uterovaginal Prolapse

See uterus, prolapse of.... uterovaginal prolapse

Vomiting In Pregnancy

Nausea and vomiting in early pregnancy are common and are most likely to be caused by changes in the hormone levels. Vomiting occurs most frequently in the morning, but it may occur at any time. It is sometimes precipitated by stress, travelling, or food.

In rare cases, the vomiting becomes severe and prolonged. This can cause dehydration, nutritional deficiency, alterations in blood acidity, and weight loss. Immediate hospital admission is then required to replace lost fluids and chemicals by intravenous infusion, to rule out any serious underlying disorder, and to control the vomiting.... vomiting in pregnancy

Z-plasty

A technique that is used in plastic surgery to change the direction of a pre-existing scar so that it can be hidden in natural skin creases, or to relieve skin tension caused by the contracture of a scar.

Z-plasty is especially useful for revising unsightly scars on the face and for releasing scarring across those joints, such as on the fingers or in the armpits, that may restrict normal movement or cause deformity.... z-plasty

Urination, Painful

Pain or discomfort that occurs when urine is being passed. Painful urination is known medically as dysuria. The pain is often described as burning; sometimes it is preceded by difficulty in starting urine flow. Pain after the flow has ceased, with a strong desire to continue, is called strangury.

The most common cause, especially in women, is cystitis. Other causes include a bladder tumour, bladder stone (see calculus, urinary tract), urethritis, balanitis, prostatitis, vaginal candidiasis (thrush), or allergy to vaginal deodorants. Strangury is usually caused by spasm of an inflamed bladder wall, but it may be due to bladder stones. Mild discomfort when passing urine may be caused by highly concentrated urine.

Dysuria may be investigated by physical examination, urinalysis, urography, or cystoscopy. (See also urethral syndrome, acute.)... urination, painful

Uterus, Prolapse Of

A condition in which the uterus descends from its normal position into the vagina. The degree of prolapse varies from 1st-degree prolapse, in which there is only slight displacement of the uterus, to 3rd-degree prolapse (procidentia), in which the uterus can be seen outside the vulva.

Stretching of the ligaments supporting the uterus (during childbirth, for example) is the most common cause. Prolapse is aggravated by obesity.

There are often no symptoms, but sometimes there is a dragging feeling in the pelvis. Diagnosis is made by physical examination.

Pelvic floor exercises strengthen the muscles of the vagina and thus reduce the risk of a prolapse, especially following childbirth. Treatment usually involves surgery (hysterectomy). Rarely, if surgery is not wanted or is not recommended, a plastic ring-shaped pessary may be inserted into the vagina to hold the uterus in position. (See also cystocele; rectocele; urethrocele.)... uterus, prolapse of

Abruptio Placentae

(placental abruption) bleeding from a normally situated placenta causing its complete or partial detachment from the uterine wall after the 24th week of gestation. Abruption is often an unanticipated emergency, as a small bleed (*antepartum haemorrhage) can suddenly evolve into a major abruption and *disseminated intravascular coagulation. Abruptio placentae is often associated with hypertension and pre-eclampsia.... abruptio placentae

Accessory Pathway

an extra electrical conduction pathway between the atria and ventricles, anatomically separate from the *atrioventricular node, that predisposes to *re-entry tachycardia. The pathway conducts faster than the atrioventricular node, giving rise to pre-excitation recognized by a characteristic delta wave at the beginning of the QRS complex on the electrocardiogram in normal rhythm. The presence of this pathway, with the occurrence of intermittent tachycardias, is known as the *Wolff-Parkinson-White syndrome.... accessory pathway

Acesulfame Potassium

an artificial sweetener (E950) 200 times sweeter than sugar. It is often used in combination with other sweeteners to produce a superior flavour. Not metabolized by the body, it is suitable for use in diabetic foods and can be used in cooking.... acesulfame potassium

Action Potential

the change in voltage that occurs across the membrane of a nerve or muscle cell when a *nerve impulse is triggered. It is due to the passage of charged particles across the membrane (see depolarization) and is an observable manifestation of the passage of an impulse.... action potential

Active/passive

adj. the ethical distinction between actively doing something to a patient and simply allowing it to happen or failing to act (the acts and omissions doctrine). For instance, doctors should act to save life if possible, but when death is inevitable it is permissible to let it happen, although the prohibition against killing would not allow active intervention. See also dying.... active/passive

Acute Fatty Liver Of Pregnancy

a rare and life-threatening complication of pregnancy that usually presents in the third trimester with symptoms of nausea, vomiting, malaise, and abdominal pain. Liver function tests are abnormal and the features of *pre-eclampsia and often *HELLP syndrome are present. *Hepatic encephalopathy, *disseminated intravascular coagulation, and renal failure may develop, and the condition is associated with a high maternal and fetal mortality. Treatment involves a multidisciplinary approach, usually in an intensive care unit.... acute fatty liver of pregnancy

Acute Generalized Exanthematous Pustulosis

(toxic pustuloderma) a reaction to a medication, resulting in the appearance of fine sterile *pustules on inflamed skin; the pustules may easily be overlooked. Common causes include penicillins, and pustular psoriasis must be excluded from the diagnosis.... acute generalized exanthematous pustulosis

Adie’s Pupil

see tonic pupil. [W. J. Adie (1886–1935), British physician]... adie’s pupil

Advanced Glycation End-products

damaged proteins that result from the *glycation of a large number of body proteins, which can accumulate and cause permanent damage to tissues. This damage is more prevalent in diabetics due to chronic exposure to blood with high concentrations of glucose. It is believed to be partly responsible for the damage to the kidneys, eyes, and blood vessels that characterizes long-standing diabetes.... advanced glycation end-products

Alara Principle

see radiation protection.... alara principle

Allied Health Professional

a health-care professional with expert knowledge and experience in certain fields but without a medical or nursing qualification. Allied health professionals include speech and language therapists, radiographers, physiotherapists, occupational therapists, and dieticians.... allied health professional

Anatomical Position

the internationally accepted body position for anatomical descriptions, such that any part of the body can be related to any other part of it. A person in the anatomical position stands erect, the arms hanging by the sides with the palms facing frontwards and the legs and feet together with the toes pointing forwards (see illustration overleaf).... anatomical position

Anomalous Pulmonary Venous Drainage

a congenital abnormality in which the pulmonary veins enter the right atrium or vena cava instead of draining into the left atrium. The clinical features are those of an *atrial septal defect.... anomalous pulmonary venous drainage

Antigen-presenting Cell

(APC) a cell, such as a *dendritic cell or a *macrophage, that processes antigen for presentation to a T lymphocytes (see helper T cell).... antigen-presenting cell

Antitachycardia Pacing

termination of a *tachycardia by temporarily pacing the heart at a faster rate.... antitachycardia pacing

Any Qualified Provider

(AQP) any of a range of suitable health-care providers in a scheme operating in the National Health Service from whom patients can choose to receive their care. These include providers from outside the NHS, such as social enterprises, charities, or private sector providers.... any qualified provider

Argon Plasma Coagulation

an endoscopic procedure used predominantly to control bleeding in the gastrointestinal tract. secondary to angiodysplasia and bleeding following polypectomy. Occasionally it is used in the debulking of tumours not amenable to surgery. An intermittent stream of argon gas is delivered through a catheter in the endoscope and ionized by a monopolar electrical current producing a controlled release of thermal energy. This causes coagulation in the adjacent tissues.... argon plasma coagulation

Asbestos-related Pleural Disease

any one of a variety of conditions involving the *pleura, but not the lungs (see asbestosis), in subjects exposed to asbestos. These include the formation of pleural plaques, diffuse pleural thickening, and pleural effusions (see oedema).... asbestos-related pleural disease

Atypical Facial Pain

see persistent idiopathic facial pain.... atypical facial pain

Atypical Pneumonia

any one of a group of community-acquired *pneumonias that do not respond to penicillin but do respond to such antibiotics as tetracycline and erythromycin. They include infection with Mycoplasma pneumoniae, Chlamydia psittaci (see psittacosis), and Coxiella burnetii (see Q fever).... atypical pneumonia

Auditory Processing Disorder

(APD, central auditory processing disorder, CAPD) a series of conditions characterized by difficulty in hearing and processing auditory information, especially in poor acoustic environments, despite normal or near-normal ear function. It may be due to genetic factors, maturational delay in the central nervous system, or focal abnormalities of the central nervous system (such as tumours). Treatments include *hearing therapy, *auditory skills training, educational support, use of *assistive listening devices, and training with computerized therapy tools.... auditory processing disorder

Auerbach’s Plexus

(myenteric plexus) a collection of nerve fibres – fine branches of the *vagus nerve – within the walls of the intestine. It supplies the muscle layers and controls the movements of *peristalsis. [L. Auerbach (1828–97), German anatomist]... auerbach’s plexus

Automated Perimeter

see perimeter.... automated perimeter

Base Pairing

the linking of the two strands of a DNA molecule by means of hydrogen bonds between the bases of the nucleotides. Adenine always pairs with thymine and cytosine with guanine. See DNA.... base pairing

Bell’s Phenomenon

the normal outward and upward rotation of the eyes that occurs when the lids are closed, but not during blinking. [Sir C. Bell]... bell’s phenomenon

Bence-jones Protein

a protein of low molecular weight found in the urine of patients with multiple *myeloma and rarely in patients with *lymphoma, *leukaemia, and *Hodgkin’s disease. [H. Bence-Jones (1814–73), British physician]... bence-jones protein

Bile Pigments

coloured compounds – breakdown products of the blood pigment *haemoglobin – that are excreted in *bile. The two most important bile pigments are bilirubin, which is orange or yellow, and its oxidized form biliverdin, which is green. Mixed with the intestinal contents, they give the brown colour to the faeces (see urobilinogen).... bile pigments

Bi-level Positive Airways Pressure

see BiPAP.... bi-level positive airways pressure

Binge–purge Syndrome

see bulimia.... binge–purge syndrome

Biophysical Profile

a physiological assessment of fetal wellbeing, based on scores for each of the following: fetal breathing, fetal movement, fetal tone, and *amniotic fluid volume (as observed on ultrasound) and fetal heart rate (measured by *cardiotocography). The maximum score is 10 (with 2 points for each component).... biophysical profile

Benign Paroxysmal Positional Vertigo

(BPPV) a common cause of vertigo in which the patient complains of brief episodes of rotatory vertigo precipitated by sudden head movements. It is thought to be due to microscopic debris derived from the *otoliths of the utricle and displaced into one of the semicircular canals, most commonly the posterior semicircular canal. The debris is most commonly thought to be free in the canal (canalithiasis; see canalith) but can be attached to the *cupula (cupulolithiasis; see cupulolith). Diagnosis is by performing a *Dix–Hallpike test. Treatment is with a predetermined set of head movements to move the debris from the semicircular canal (see Epley particle repositioning manoeuvre; Semont liberatory manoeuvre; Brandt-Daroff exercises). Surgery is occasionally used to occlude the relevant semicircular canal, cut the *singular nerve or vestibular nerves, or perform a *labyrinthectomy. Drugs are generally ineffective in the treatment of this condition.... benign paroxysmal positional vertigo

Bladder Pressure Study

a combined X-ray and manometry examination of the bladder to look for abnormal function. The bladder is filled slowly with contrast medium using a small urinary catheter and the pressure is monitored during filling and voiding (micturition). X-ray images of the bladder and urethra (see urethrography) are taken. The test is used to differentiate between obstruction to bladder outflow and abnormal involuntary contractions of the muscle in the bladder wall.... bladder pressure study

Blind And Partially Sighted Register

(in Britain) an incomplete list of persons who are technically blind or partially sighted due to reduced visual acuity, or who have severely restricted fields of vision (see blindness). Registration is voluntary, but it is a precondition for the receipt of some financial benefits. The list is maintained by local authorities (England and Wales), regional or island councils (in Scotland), or the Health and Social Care Board (Northern Ireland).... blind and partially sighted register

Blood Plasma See Plasma.

... blood plasma see plasma.

Brain Natriuretic Peptide

(BNP) see natriuretic peptide.... brain natriuretic peptide

Branchial Pouch

see pharyngeal pouch.... branchial pouch

Bronchiolitis Obliterans Organizing Pneumonia

(BOOP) a disease entity characterized clinically by a flulike illness with cough, fever, shortness of breath, and late inspiratory crackles; there are specific histological features and patchy infiltrates on X-ray. It is sometimes the result of a viral infection, but may follow medication with certain drugs or be associated with connective-tissue disease, such as rheumatoid arthritis. The condition usually responds to oral corticosteroids; however, if a drug is implicated, it must be withdrawn.... bronchiolitis obliterans organizing pneumonia

Bullous Pemphigoid

see pemphigoid.... bullous pemphigoid

Calcium Pyrophosphate Deposition Disease

a condition in which calcium pyrophosphate is deposited in joints. The most common manifestation is *pseudogout, marked by acute pain, redness, and swelling resembling gout. Alternatively it may be asymptomatic in association with *chondrocalcinosis seen on X-ray, it may occur with osteoarthritis in the affected joint, or there may be chronic inflammation of the joint.... calcium pyrophosphate deposition disease

Cancer Phobia

a disorder of the phobic type in which minor symptoms are interpreted as signs of cancer and panic attacks may occur. As with any other phobic disorder, cancer phobia cannot be treated by appeals to reason. Some success has been achieved by various forms of *behaviour therapy and *SSRIs.... cancer phobia

Carbamide Peroxide

a urea peroxide compound that is commonly used in tooth-whitening agents, anti-infective agents, and earwax remover.... carbamide peroxide

Central Auditory Processing Disorder

see auditory processing disorder.... central auditory processing disorder

Central Pontine Myelinolysis

acute paralysis, dysphagia, and dysarthria resulting from damage to the myelin sheaths of nerve cells in the brainstem. It occurs most commonly as a complication of rapid correction of severe hyponatraemia (low serum sodium).... central pontine myelinolysis

Charity Patients

in the USA, very low-income patients who receive health care free or at reduced prices; criteria for eligibility differ from state to state, hospital to hospital, and physician to physician. Providers of charity care may be reimbursed through *Medicaid, *Medicare, or other government programmes. So-called medically indigent patients may also be eligible for help. These are patients who earn too much to qualify for charity care but not enough to afford health insurance, and who may incur medical bills that are far beyond their means. The *Affordable Care Act 2010 was intended largely to help those in this position.... charity patients

Child Protection Register

(in Britain) a confidential list of children whose social circumstances render them at risk of neglect or abuse. Each local authority maintains a register of children who are subject to a child protection plan, who will receive extra support and surveillance from health and/or social services. See also safeguarding.... child protection register

Children’s Auditory Performance Scale

(CHAPS) a questionnaire designed to assess children’s hearing abilities in certain situations. It is used in the diagnosis of *auditory processing disorder.... children’s auditory performance scale

Child–turcotte–pugh Score

a clinical scoring system used to predict the one- and two-year survival rates of patients with chronic liver disease. The score is determined by the assessment of two clinical signs (the presence of ascites and *hepatic encephalopathy) and three biochemical markers (serum bilirubin level, serum albumin level, and prothrombin time).... child–turcotte–pugh score

Chronic Idiopathic Facial Pain

see persistent idiopathic facial pain.... chronic idiopathic facial pain

Chronic Pelvic Pain

(CPP) intermittent or constant pain in the lower abdomen or pelvis of at least six months’ duration, not occurring exclusively with menstruation or intercourse and not associated with pregnancy. It may be caused by an underlying gynaecological condition, such as *endometriosis or adhesions, but bowel or bladder disorders (e.g. irritable bowel syndrome, interstitial cystitis), visceral hypersensitivity, and psychological conditions may all contribute.... chronic pelvic pain

Chronic Sick And Disabled Persons Act 1970

(in Britain) an Act providing for the identification and care of those suffering from a chronic or degenerative disease for which there is no cure and which can be only partially alleviated by treatment. Such people are usually distinguished from the elderly who may also suffer from chronic diseases. It is the responsibility of local authorities to identify those with such problems and to ensure that services are available to meet their needs. Identification can be difficult because of the lack of a clear and agreed definition of what constitutes a disability of such severity as to warrant inclusion in such a register.... chronic sick and disabled persons act 1970

Coal-worker’s Pneumoconiosis

a lung disease caused by coal dust. It affects mainly coal miners but also other exposed workers, such as lightermen, if the lungs’ capacity to accommodate and remove the particles is exceeded. See pneumoconiosis.... coal-worker’s pneumoconiosis

Cognitive Psychology

the branch of psychology concerned with all human activities relating to knowledge. More specifically, cognitive psychology is concerned with how knowledge is acquired, stored, correlated, and retrieved, by studying the mental processes underlying attention, concept formation, information processing, memory, and speech. Cognitive psychology views the brain as an information-processing system operating on, and storing, the data acquired by the senses. It investigates this function by experiments designed to measure and analyse human performance in carrying out a wide range of mental tasks. The data obtained allows possible models of the underlying mental processes to be constructed. These models do not purport to represent the actual physiological activity of the brain. Nevertheless, as they are refined by testing and criticism, it is hoped that they may approach close to reality and gradually lead to a clearer understanding of how the brain operates.... cognitive psychology

Collapsing Pulse

see Corrigan’s pulse.... collapsing pulse

Community-acquired Pneumonia

(CAP) see pneumonia.... community-acquired pneumonia

Complex Partial Seizure

see epilepsy.... complex partial seizure

Consultant In Health Protection

(CHP) a consultant within *Public Health England who is responsible for the surveillance, prevention, and control of communicable disease and noncommunicable environmental exposures. While no longer the preferred term, the older form Consultant in Communicable Disease Control (CCDC) is still sometimes used. See also public health consultant.... consultant in health protection

Continuous Patient Pathway

the route that a patient takes through the health-care system, from first admission to a hospital or treatment centre to final discharge. This may consist of one or more *spells in particular hospitals and one or more *finished consultant episodes. For example, a patient admitted to a district general hospital, transferred to a tertiary hospital for a specialist procedure, and then transferred back to the district general hospital for recovery would experience one continuous patient pathway but three spells.... continuous patient pathway

Co-phenotrope

n. a drug used in the treatment of diarrhoea. It consists of a mixture of diphenoxylate hydrochloride (an opioid that reduces *peristalsis) and atropine (which relaxes the smooth muscle of the gut) in a ratio of 100 to 1.... co-phenotrope

Coracoid Process

a beaklike process that curves upwards and forwards from the top of the *scapula, over the shoulder joint.... coracoid process

Cord Presentation

the position of the umbilical cord when it lies below the presenting part of the fetus in an intact bag of membranes. See also cord prolapse.... cord presentation

Cord Prolapse

rupture of the membranes in cases of a *cord presentation. It is an obstetric emergency: there is a severe risk of cord compression and spasm causing fetal asphyxia (see hypoxic-ischaemic encephalopathy). Delivery must occur as soon as possible and the presenting part displaced away from the cord.... cord prolapse

Complex Regional Pain Syndrome

(CRPS, reflex sympathetic dystrophy, RSD, Sudek’s atrophy) neurological dysfunction in a limb following trauma, surgery, or disease, characterized by intense burning pain, swelling, stiffness, and sweaty shiny mottled skin. It is caused by overactivity of the sympathetic nervous system. The *ESR is often elevated, X-rays may reveal some patchy osteoporosis, and a bone scan usually demonstrates increased blood flow. Early treatment with splinting and physiotherapy are essential, in combination with *sympatholytic drugs, corticosteroids, and regional sympathetic blocks; *sympathectomy may be required in chronic cases.... complex regional pain syndrome

Coronoid Process

1. a process on the upper end of the *ulna. It forms part of the notch that articulates with the humerus. 2. the process on the ramus of the *mandible to which the temporalis muscle is attached.... coronoid process

Corrigan’s Pulse

(collapsing pulse) a type of pulse that has an exaggerated rise followed by a sudden fall. It is typical of *aortic regurgitation. [Sir D. J. Corrigan (1802–80), Irish physician]... corrigan’s pulse

Cox Maze Procedure

a cardiac surgical procedure performed to prevent atrial *fibrillation. Multiple atrial incisions are made in a mazelike pattern. These incisions heal with scar tissue that does not conduct electricity, thus interrupting the abnormal electrical impulses that trigger atrial fibrillation. [J. Cox (21st century), US surgeon]... cox maze procedure

C-peptide

n. a peptide (so-called because of its C shape) formed when insulin is produced from its precursor molecule, proinsulin. It is secreted in equal molar amounts to insulin. However, as it remains detectable in the plasma much longer than insulin it can be more easily assayed as a marker of the degree of insulin secretion. This can be useful to assess the ability of the pancreas to secrete insulin, for example when trying to determine whether somebody has type 1 or type 2 diabetes or to distinguish an insulin-secreting tumour (an *insulinoma) from surreptitious insulin usage in somebody presenting with unexplained hypoglycaemia.... c-peptide

Cribriform Plate

see ethmoid bone.... cribriform plate

Cricoid Pressure

a technique in which a trained assistant presses downwards on the *cricoid cartilage of a supine patient to aid endotracheal *intubation.... cricoid pressure

Cystosarcoma Phylloides

a malignant tumour of the connective tissue of the breast: it accounts for approximately 1% of all breast cancers. Such tumours may show a wide variation in cell structure and they often present as a large mass but without distant spread. The best treatment for a localized tumour is simple *mastectomy.... cystosarcoma phylloides

Data Protection

legal safeguards relating to the use and storage of personal information about a living person. Under the Data Protection Act 2018, which implements the EU’s General Data Protection Regulation (GDPR) and supersedes the Data Protection Act 1998, individuals have a basic right to control information stored about them. Information concerning health, considered ‘sensitive personal data’ under the legislation, must be used only for the purpose (health care of the individual) for which it was gathered, must be kept secret, and cannot be used or passed on to others without the knowledge of the subject. However, anonymized health data from individual patients’ electronic records may be used for research purposes or to improve medical treatment and health-service delivery.... data protection

Defibrillation Gel Pads

see coupling agents.... defibrillation gel pads

Delusional Parasitosis

see delusional infestation.... delusional parasitosis

Delusional Perception

a *Schneiderian first-rank symptom in which a person believes that a normal percept (product of perception) has a special meaning for him or her. For example, a cloud in the sky may be misinterpreted as meaning that someone has sent that person a message to save the world. While the symptom is particularly indicative of *schizophrenia, it also occurs in other psychoses, including *mania (in which it often has grandiose undertones).... delusional perception

Dental Pantomogram

(DPT) a special form of tomogram (see tomography) that provides a picture of all the teeth of both jaws on one film. Newer equipment can produce three-dimensional images of part of the jaw.... dental pantomogram

Dependent Practitioner

in the USA, a paraprofessional or subprofessional health-care worker who is allowed to provide a limited amount of treatment to patients, usually under the supervision of a licensed practitioner, such as a physician. Examples include a nurse practitioner or occupational therapist.... dependent practitioner

Dermatofibrosarcoma Protuberans

a tumour probably derived from *histiocytes that may occur in any part of the body. It is locally invasive but tends not to metastasize. It often recurs locally despite excision.... dermatofibrosarcoma protuberans

Dew-point Hygrometer

see hygrometer.... dew-point hygrometer

Dawn Phenomenon

(Somogyi effect) the phenomenon of high fasting blood-sugar levels in the morning due to an unrecognized hypoglycaemic episode during the night in a person with diabetes. The low blood sugar has resulted in an outpouring of regulatory hormones, such as adrenaline and glucagon, which have raised the blood sugar to supranormal levels by the time of waking. It is important to recognize the cause, since increasing the evening insulin dose, thinking this will bring the morning sugars down, could actually cause a more severe nocturnal hypoglycaemic attack, which the body may not be able to counteract: coma might ensue. The condition can be tested for by measuring blood sugars at the time of the assumed low level.... dawn phenomenon

Delusion By Proxy

a delusion in which the patient believes that another person or an animal (usually the patient’s pet) has certain physical symptoms, even though these cannot be objectively verified. The patient with the delusional belief is called the inducer; the person or pet that is allegedly affected is the proxy. Some *monodelusional disorders, such as *delusional infestation, have a prevalence of delusion by proxy of up to 5%. Treatment is usually with *antipsychotics. In some situations it may be necessary to remove the proxy to provide safety from the behaviour associated with the delusion. See also double delusion; folie à deux.... delusion by proxy

Dental Care Professional

any of several professionals supporting a dentist, formerly referred to as dental auxiliaries and professionals complementary to dentistry. A dental hygienist performs scaling and instruction in oral hygiene. A dental nurse helps the dentist at the chairside by preparing materials, passing instruments, and aspirating fluids from the patient’s mouth. A dental technician constructs dentures, crowns, and orthodontic appliances in the laboratory for the dentist. A clinical dental technician provides dentures directly to patients. A dental therapist performs non-complex treatment under the prescription of a dentist. In the UK dental care professionals are required to be statutorily registered with the General Dental Council (GDC).... dental care professional

Diabetic Honeymoon Period

a well-recognized period just after the diagnosis of type 1 *diabetes mellitus when only very low insulin doses are required to control the condition. It lasts from months to a few years but inevitably ends, when dose requirements will increase quite quickly.... diabetic honeymoon period

Diagnostic Peritoneal Lavage

the instillation of saline directly into the abdominal cavity and its subsequent aspiration a few minutes later. If the fluid is bloodstained on recovery an intra-abdominal haemorrhage is indicated. This is a useful diagnostic tool in trauma patients.... diagnostic peritoneal lavage

Director Of Public Health

(DPH) a senior public health consultant or specialist in a local authority. Responsibilities include advising on the health needs of the local population. See also public health consultant; public health specialist.... director of public health

Disodium Pamidronate

see pamidronate.... disodium pamidronate

Dispensing Practice

(in Britain) a general practice with a dispensary on site to issue prescribed medications to patients. See also general practitioner.... dispensing practice

Dna Polymerase Inhibitor

any one of a class of antiviral drugs that inhibit the action of DNA polymerase enzymes, which are used by viruses to form their own DNA. These drugs prevent, to a varying degree, the reproduction of viruses. They include *aciclovir, *foscarnet, *ganciclovir, and *valaciclovir.... dna polymerase inhibitor

Echo De La Pensée

see thought echo.... echo de la pensée

Elschnig Pearls

round or oval transparent cystic structures on the posterior capsule of the lens due to proliferation of lens epithelial cells following extracapsular *cataract extraction. They can grow to cover the central part of the capsule and cause reduction in vision. [A. Elschnig (1863–1939), German ophthalmologist]... elschnig pearls

End-plate

n. the area of muscle cell membrane immediately beneath the motor nerve ending at a *neuromuscular junction. Special receptors in this area trigger muscular contraction when the nerve ending releases its *neurotransmitter.... end-plate

Entoptic Phenomena

visual sensations caused by changes within the eye itself, rather than by the normal light stimulation process. The commonest are tiny floating spots (floaters) that most people can see occasionally, especially when gazing at a brightly illuminated background (such as a blue sky).... entoptic phenomena

Eosinophilic Granulomatosis With Polyangiitis

see Churg–Strauss syndrome.

EPA (eicosapentaenoic acid) see omega-3 fatty acids.... eosinophilic granulomatosis with polyangiitis

Epley Particle Repositioning Manoeuvre

a series of head and body movements used to move microscopic debris from the posterior *semicircular canal in the inner ear. It is used in the treatment of *benign paroxysmal positional vertigo.... epley particle repositioning manoeuvre

Emotionally Unstable Personality Disorder

a *personality disorder characterized by a tendency to act impulsively without consideration of the consequences, unpredictable and capricious mood, a tendency towards outbursts of emotion, inability to control behavioural explosions, quarrelsome behaviour, and conflict with others. There is an impulsive type, with particular emphasis on impulsivity and quarrelsome behaviour, especially when criticized; and a borderline type, with an emphasis on disturbance and uncertainty about self-image (including sexual preference), liability to become involved in intense and unstable relationships, excessive efforts to avoid abandonment, recurrent threats or acts of self-harm, and chronic feelings of emptiness. Treatments include cognitive analytical therapy (see cognitive therapy), *antipsychotic medication, and occasionally *SSRIs and *lithium. In DSM-5 the disorder is called borderline personality disorder.... emotionally unstable personality disorder

Erb’s Palsy

weakness or paralysis of the shoulder and arm usually caused by injury to the upper roots of the *brachial plexus during traumatic childbirth. This may happen if, during a difficult delivery, excess traction applied to the head damages the fifth and sixth cervical roots of the spinal cord. The muscles of the shoulder and the flexors of the elbow are paralysed and the arm hangs at the side internally rotated at the shoulder with the forearm pronated (waiter’s-tip deformity). Recovery may be spontaneous, but in some cases nerve grafts or muscle transfers are required. [W. H. Erb (1840–1921), German neurologist]

ERCP (endoscopic retrograde cholangiopancreatography) the technique in which a catheter is passed through a *duodenoscope into the *ampulla of Vater of the common bile duct and injected with a radiopaque medium to outline the pancreatic duct and bile ducts radiologically. Magnetic resonance cholangiopancreatography (MRCP; see cholangiography) is often used to diagnose biliary and pancreatic disease followed by ERCP for diagnostic confirmation and therapeutic intervention. ERCP facilitates the removal of gallstones from the common bile duct, biopsy of lesions, and insertion of biliary *stents. See also papillotomy.... erb’s palsy

Facial Paralysis

paralysis of the facial nerve, causing weakness and loss of function of the muscles it serves. It occurs in *Bell’s palsy. The commonest cause is infection with the herpes simplex virus.... facial paralysis

Faculty Of Public Health

(FPH) a joint faculty of the three Royal Colleges of Physicians of the United Kingdom and the standard setting body for specialists in public health in the UK. It aims to promote public health, develop the public health workforce, and act as an authoritative body offering consultation and advocacy on matters concerning public health. It assesses public health trainees and makes recommendations for inclusion on the GMC specialist register and UK voluntary register for public health professionals.

The FPH website... faculty of public health

Faecal Pancreatic Elastase

see elastase.... faecal pancreatic elastase

False Pregnancy

see pseudocyesis.... false pregnancy

Familial Adenomatous Polyposis

(FAP) see polyposis.... familial adenomatous polyposis

Family Practitioner

see general practitioner.... family practitioner

Fetus Papyraceous

a twin fetus that has died in the uterus and become flattened and mummified.... fetus papyraceous

Fibroepithelial Polyp

a fibrous overgrowth covered by epithelium, often occurring inside the mouth in response to chronic irritation (usually following accidental biting). It is sometimes called a fibrous *epulis.... fibroepithelial polyp

First-pass Metabolism

a process in which a drug administered by mouth is absorbed from the gastrointestinal tract and transported via the portal vein to the liver, where it is metabolized. As a result, in some cases only a small proportion of the active drug reaches the systemic circulation and its intended target tissue. First-pass metabolism can be bypassed by giving the drug via sublingual or buccal routes.... first-pass metabolism

Flat-panel Detector

a piece of equipment used instead of a conventional X-ray film to acquire the image in *digital radiography.... flat-panel detector

Fluticasone Proprionate

a corticosteroid used for the prophylaxis of asthma, the prophylaxis and treatment of hay fever and perennial rhinitis, and the treatment of dermatitis and eczema.... fluticasone proprionate

Forced Preferential Looking Test

(FPL test) a test used to evaluate the *visual acuity of infants and young children by observing whether the child looks at a blank screen or one with stripes, the spatial frequency of which can be changed.... forced preferential looking test

Forward Parachute Reflex

a reflex action of the body that develops by five to six months and never disappears. If the body is held by the waist face down and lowered, the arms and legs extend automatically.... forward parachute reflex

Foundation Programme

a two-year programme of postgraduate medical training, introduced as part of the Modernizing Medical Careers initiative in 2005. Foundation year 1 replaced the old preregistration house officer year, and foundation year 2 replaced the first year of senior house officer training. See also Doctor.... foundation programme

Four Principles

an approach to medical ethics, proposed by Tom Beauchamp and James F. Childress, that identifies four basic tenets of ethical practice, namely: respect for *autonomy, *beneficence, *nonmaleficence, and *justice. Although the four principles are often used as a framework for decision-making in Western medical ethics, there may be problems when principles conflict or their application is contested in practice.... four principles

Fresnel Prism

a flexible plastic prism that can be stuck to spectacle lenses to add a prism effect to spectacles. It may be used to correct double vision. [A. J. Fresnel (1788–1827), French physicist]... fresnel prism

General Practitioner

(GP) a doctor working in the community who provides family health services to a local area. General practitioners (also known as family doctors or family practitioners) may work on their own or in a group practice in which they share premises and other resources with one or more other doctors. GPs are usually the first port of call for most patients with concerns about their health. They look after patients with wide-ranging medical conditions and can refer patients with more complex problems to specialists, such as hospital consultants. Some GPs with additional training and experience in a specific clinical area take referrals for assessment and treatment that may otherwise have been referred directly to hospital consultants; these are known as GPs with a special interest (GPwSI or GPSI). Most GPs work solely within the *National Health Service but a few work completely privately. The current model of general practice allows for GPs to provide general medical services (GMS), the terms and conditions of which are governed by a national contract which is usually negotiated on an annual basis, or personal medical services (PMS), the terms and conditions of which are governed by locally negotiated contracts within a broad framework. The new primary care contract (nGMS contract) came into force in April 2004, allowing GPs to opt out of weekend and night (*out-of-hours) service provision for patients registered with their practice. In this period, patient care is usually provided by an out-of-hours cooperative or deputizing service. At the same time the government also introduced the *Quality and Outcomes Framework (QOF) as a means to improve the quality of care provided. Most GPs are *independent contractors although more recently there has been an increase in the number of salaried GPs. GPs may employ a variety of staff, including *practice nurses, *nurse practitioners, and counsellors.... general practitioner

General Practitioner With Special Interest

(GPwSI, GPSI) see general practitioner.... general practitioner with special interest

Germ Plasm

the substance postulated by 19th-century biologists (notably Weismann) to be transmitted via the gametes from one generation to the next and to give rise to the body cells.... germ plasm

Globus Pharyngeus

a common condition characterized by a sensation of a lump in the throat, in the midline just above the sternum; swallowing is not affected. The condition, formerly called globus hystericus, is sometimes related to *gastro-oesophageal reflux and tends to be worse during periods of stress.... globus pharyngeus

Glucagon-like Peptide-1

(GLP-1) a hormone – an *incretin – that is produced in the small intestine. GLP-1 has a half-life in the blood circulation of less than two minutes due to rapid breakdown by the enzyme dipeptidyl peptidase-IV (DPP-IV). It is a potent antihyperglycaemic hormone, stimulating the release of insulin from the pancreatic beta cells in response to a rising blood glucose level after eating. This glucose-sensitive action also allows the effect of GLP-1 on the beta cells to switch off when the blood glucose level comes down to the normal baseline between meals. Thus the *GLP-1 receptor agonist group of drugs, used in type 2 diabetes, can restrict the rise in blood glucose level after meals but have a low risk of causing subsequent *hypoglycaemia.... glucagon-like peptide-1

Glutamic Pyruvic Transaminase

(GPT) see alanine aminotransferase.... glutamic pyruvic transaminase

Gottron’s Papules

see dermatomyositis.... gottron’s papules

Granulomatosis With Polyangiitis

(GPA) an autoimmune disease, formerly known as Wegener’s granulomatosis, predominantly affecting the sinuses, lungs, and kidneys, and characterized by blood-vessel inflammation and the formation of necrotizing *granulomas. It is associated with the presence of antineutrophil cytoplasmic antibodies (*ANCA). Untreated the disease is usually fatal, but it can be controlled with corticosteroids, cyclophosphamide, or rituximab.... granulomatosis with polyangiitis

Growth Plate

see physis.... growth plate

Gutta-percha

n. a tough plastic substance derived from the latex of several Malaysian trees of the sapodilla family. It is hard at room temperature but becomes soft and plastic when heated. On cooling, gutta-percha will retain any shape imparted to it when hot. It is used in dentistry in the form of gutta-percha points as the principal core of *root fillings.... gutta-percha

Hair Papilla

a projection of the dermis that is surrounded by the base of the hair bulb. It contains the capillaries that supply blood to the growing *hair.... hair papilla

Happy Puppet Syndrome

see Angelman syndrome.... happy puppet syndrome

Glucose-6-phosphate Dehydrogenase Deficiency

a hereditary disorder – an X-linked condition (see sex-linked) – in which the absence of the enzyme glucose-6-phosphate dehydrogenase (G6PD), which functions in carbohydrate metabolism, results in the breakdown of the red blood cells (*haemolysis), usually after exposure to *oxidants, such as drugs, or infections. The breakdown causes acute attacks that are characterized by pallor, loin pain, and rigors. There are several varieties of G6PD deficiency, which is most common in people of African, Middle Eastern, and Mediterranean descent. Treatment involves identifying and avoiding agents that trigger the haemolysis and treating acute attacks symptomatically. See also favism.... glucose-6-phosphate dehydrogenase deficiency

Hartmann’s Pouch

a saclike dilatation of the gall-bladder wall near its outlet; it is a common site for finding *gallstones. [R. Hartmann (1831–93), German anatomist]... hartmann’s pouch

Health Protection

the branch of *public health medicine that is concerned with protecting the population from communicable diseases, chemicals and poisons, radiation, and other potential threats to health. See Public Health England.... health protection

Health Protection Agency

(HPA) formerly, a nondepartmental public body set up as a special health authority in 2003 to protect the health of the UK population via advice and support to the NHS, local authorities, the Department of Health, emergency services, and others. The HPA was abolished in April 2013; its responsibilities were largely passed to *Public Health England. See Consultant in Health Protection.... health protection agency

Health Service Planning

balancing the health and health-care needs of a community, assessed by such indices as mortality, morbidity, and disability, with the resources available to meet these needs in terms of human resources (including ensuring the numbers in training grades meet future requirements) and technical resources, such as hospitals (capital planning), equipment, and medicines. See also clinical audit.... health service planning

Heater-probe

n. a device that can be passed through an endoscope to apply controlled heat in order to coagulate a bleeding peptic ulcer.... heater-probe

Heel-prick Blood Test

see Guthrie test.... heel-prick blood test

Henoch–schönlein Purpura

(Schönlein–Henoch purpura, anaphylactoid purpura) a common, and frequently recurrent, form of *purpura found especially (but not exclusively) in young children. It is characterized by red weals and a purple rash on the buttocks and lower legs due to bleeding into the skin from inflamed capillaries, together with arthritis, gastrointestinal symptoms, and (in some cases) nephritis. Glucocorticoids are often used for treatment. [E. H. Henoch (1820–1910), German paediatrician; J. L. Schönlein (1793–1864), German physician]... henoch–schönlein purpura

Hereditary Periodic Fever Syndromes

a group of rare inherited disorders characterized by recurrent attacks of fever and inflammation in the absence of infection. They include familial Mediterranean fever (see polyserositis), tumour necrosis factor receptor-associated periodic syndrome (TRAPS), and the cryopyrin-associated periodic syndrome (CAPS). Causative gene mutations have been identified.... hereditary periodic fever syndromes

Histamine Acid Phosphate

a derivative of *histamine that was formerly used to test for acid secretion in the stomach in conditions involving abnormal gastric acid secretion, such as *Zollinger-Ellison syndrome.... histamine acid phosphate

Histrionic Personality Disorder

a type of *personality disorder characterized by excessive emotionality and attention-seeking, self-dramatization, inappropriately seductive behaviour, and an excessive need for approval. It affects more women than men. Classified as a specific personality disorder in DSM-IV-TR, in DSM-5 it is treated as a subtype of *narcissistic personality disorder.

HIV (human immunodeficiency virus) a *retrovirus responsible for *AIDS. There are two varieties, HIV-1 and HIV-2; the latter is most common in Africa. See also HTLV.... histrionic personality disorder

Human Placental Lactogen

(human chorionic somatomammotrophin) a protein hormone of 190 amino acids produced by the placenta during most but not all pregnancies. Despite its name it does not appear to have a role in lactation and its exact function remains obscure. It does, however, seem to contribute to the development of diabetes in some pregnancies.... human placental lactogen

Idiopathic Thrombocytopenic Purpura

(ITP) an *autoimmune disease in which platelets are destroyed, leading to spontaneous bruising (see purpura). Acute ITP is a relatively mild disease of children, who usually recover without treatment. A chronic form of the disease, typically affecting adults, is more serious, requiring treatment with corticosteroids or, if there is no response, with splenectomy. If both fail, immunosuppressant drugs may be effective. Platelet concentrates are used for life-threatening bleeding.... idiopathic thrombocytopenic purpura

Ileal Pouch

(perineal pouch) a reservoir made from loops of ileum to replace a surgically removed rectum, avoiding the need for a permanent *ileostomy. This is commonly constructed in patients who have had their colon surgically removed for various disorders (e.g. ulcerative colitis or familial adenomatous polyposis).... ileal pouch

Human Genome Project

a massive international research project to isolate all the genes in human DNA and determine the sequence of genes on human chromosomes. The project began in 1988 and the full draft sequence was published in 2001; the high-quality sequence was completed in 2003. The human genome comprises some 3 × 109 nucleotide base pairs (see DNA) forming 22,000–25,000 genes, distributed among 23 pairs of chromosomes. Knowledge of the entire human genome has already resulted in the identification of the genes associated with many hereditary disorders and revealed the existence of a genetic basis or component for many other diseases not previously known to have one. Theoretically, this would enable the development of targeted drugs and the large-scale genetic screening of populations. See pharmacogenomics; targeted agent.... human genome project

Idiopathic Pulmonary Fibrosis

(IPF) a serious interstitial lung disease, formerly called cryptogenic fibrosing alveolitis (see alveolitis). It is characterized by progressive fibrous scarring of the lung and increased numbers of inflammatory cells in the alveoli and surrounding tissues. The disease is usually diagnosed on clinical grounds on a basis of worsening breathlessness, inspiratory crackles at the lung bases on auscultation, clubbing of the fingers or toes, bilateral radiographic shadowing predominantly in the lower zones of the chest X-ray, subpleural *honeycomb change on CT scanning of the chest, and restrictive lung function on spirometry. It is also called usual interstitial pneumonia (UIP; see interstitial pneumonia), a term used by lung pathologists for the most common cellular pattern seen on biopsy. Treatment includes *pirfenidone, corticosteroids, and immunosuppressants.... idiopathic pulmonary fibrosis

Inosine Pranobex

a *antiviral drug that is administered by mouth to treat herpes simplex infections (cold sores and genital herpes) and genital warts.... inosine pranobex

In-patient

n. a patient who is admitted to a bed in a hospital ward and remains there for a period of time for treatment, examination, or observation. Compare out-patient.... in-patient

Integrated Care Pathway

a multidisciplinary plan for delivering health and social care to patients with a specific condition or set of symptoms. Such plans are often used for the management of common conditions and are intended to improve patient care by reducing unnecessary deviation from best practice. See clinical governance.... integrated care pathway

Intermittent Pneumatic Compression

a technique to prevent thrombosis in bedridden patients. It uses an inflatable device that squeezes the calf when it inflates, preventing pools of blood forming behind the valves in the veins, thus mimicking the effects of walking.... intermittent pneumatic compression

International Prostate Symptom Score

(IPSS) a self-administered questionnaire, completed by men with *lower urinary tract symptoms, which consists of seven questions based on the extent of symptoms and a single quality-of-life question. It gives a numerical score, on a scale of 0 to 35, to indicate the severity of the patient’s symptoms. A score of 0–7 indicates mild symptoms, 8–19 moderate symptoms, and 20–35 severe symptoms. The quality-of-life question is scored from 0–6.... international prostate symptom score

Interstitial Pneumonia

(interstitial pneumonitis) an alternative name for *idiopathic pulmonary fibrosis used by lung pathologists to classify the different cellular types of the disease. The most common cellular pattern is usual interstitial pneumonia (UIP). A differing cellular pattern is seen in patients with nonspecific interstitial pneumonia (NSIP), who have a better prognosis than those with UIP. There are two variants of NSIP: cellular and fibrosing. The former has chronic inflammatory cells with minimal collagen deposition, while the latter consists of diffuse interstitial fibrosis with fewer inflammatory cells. It is believed that corticosteroid therapy can slow the progression of cellular to fibrosing NSIP.... interstitial pneumonia

Intravenous Pyelography

(IVP) see pyelography.... intravenous pyelography

Jod–basedow Phenomenon

a collection of symptoms that includes skin rash, conjunctivitis, salivary gland inflammation, and hyperthyroidism due to the intake of high doses of iodine (German Jod, hence the name). [K. A. von Basedow (1799–1854), German physician]... jod–basedow phenomenon

Jugular Venous Pressure

(JVP) the pressure in the internal jugular vein, which is an indirect measurement of *central venous pressure (CVP) in the right atrium. In clinical practice the JVP is estimated by visual inspection at the bedside with the patient reclining at 45 degrees.... jugular venous pressure

Juvenile Plantar Dermatosis

see dermatosis.... juvenile plantar dermatosis

Juvenile Polyp

see polyp.... juvenile polyp

Kernohan’s Phenomenon

(Kernohan’s syndrome) *hemiplegia that is *ipsilateral to the brain lesion that caused it, due to pressure of the lesion (which is often a haematoma) on surrounding structures in the brain. It is unusual because normally a lesion of the brain causes dysfunction in the *contralateral limbs. [J. W. K. Kernohan (20th century), US pathologist]... kernohan’s phenomenon

Kiesselbach’s Plexus

a collection of capillaries in the mucosa at the anterior part of the nasal septum. Nosebleeds frequently have their origin from this plexus. See epistaxis; Little’s area. [W. Kiesselbach (1839–1902), German laryngologist]... kiesselbach’s plexus

Knee-elbow Position

the buttocks-up position assumed by patients undergoing anorectal examinations, now commonly performed in the left lateral position. It is useful for helping patients dispel excess flatus following colonoscopy.... knee-elbow position

Koebner Phenomenon

(isomorphic response) a phenomenon that occurs in skin diseases, especially psoriasis and lichen planus, in which the characteristic lesions of the disease appear in linear form in response to such trauma as cuts, burns, or scratches. [H. Koebner (1834–1904), German dermatologist]... koebner phenomenon

Lateral Parapharyngeal Space

see parapharyngeal space.... lateral parapharyngeal space

Legg–calvé–perthes Disease

(Perthes disease, pseudocoxalgia) necrosis of the head of the femur (thigh bone) due to interruption of its blood supply (see osteochondritis). Of unknown cause, it occurs most commonly in boys between the ages of 5 and 10 and causes aching and a limp. The head of the femur can collapse and become deformed, resulting in a short leg and restricted hip movement. Affected boys are kept under observation and their activities are restricted; surgery may be required in more severe cases. [A. T. Legg (1874–1939), US surgeon; J. Calvé (1875–1954), French orthopaedist; G. C. Perthes (1869–1927), German surgeon]... legg–calvé–perthes disease

Liaison Psychiatry

the interface between medicine and psychiatry, recognized by the Royal College of Psychiatrists as a specialty of psychiatry. Liaison teams ideally consist of psychiatric nurses, psychiatrists, psychologists, pharmacists, health-care support workers, and social workers. They are usually located in general hospitals and see patients after *deliberate self-harm or when a mental illness or *delirium is suspected anywhere in the hospital, in order to diagnose and advise on treatment. They offer *psychosocial assessments, treatment plans, medication advice, and advice regarding mental health and capacity legislation, and support ward staff with the management of challenging patients. They also help develop plans for earlier discharges, provide training, and support governance structures.... liaison psychiatry

Linitis Plastica

(leather-bottle stomach) diffuse infiltration of the stomach submucosa with malignant tissue, producing rigidity, narrowing, and reduced luminal capacity. Endoscopic diagnosis may be difficult (typically the stomach does not distend during air insufflation at gastroscopy) but radiological changes are more marked.... linitis plastica

Matched Pair Study

see case control study.... matched pair study

Maximin Principle

see veil of ignorance.... maximin principle

Maximum Intensity Projection

(MIP) a *post-processing technique used in CT and MRI scanning. When projecting a volume, maximum brightness encountered along the viewing plane will be displayed. This is particularly useful in vascular imaging.... maximum intensity projection

Mcburney’s Point

the point on the abdomen that overlies the anatomical position of the appendix and is the site of maximum tenderness in acute appendicitis. It lies one-third of the way along a line drawn from the anterior superior iliac spine (the projecting part of the hipbone) to the umbilicus. [C. McBurney (1845–1913), US surgeon]... mcburney’s point

Medically Indigent Patients

see charity patients.... medically indigent patients

Medicines And Healthcare Products Regulatory Agency

(MHRA) a UK government agency that regulates the use of medicinal drugs and medical devices. The agency regulates and issues *licences for the clinical trial, manufacture, and marketing of new products. It also applies the regulations governing the collection, storage, and use of human blood and blood products.

MHRA section of the website... medicines and healthcare products regulatory agency

Meissner’s Plexus

(submucous plexus) a fine network of parasympathetic nerve fibres in the wall of the alimentary canal, supplying the muscles and mucous membrane. [G. Meissner (1829–1905), German physiologist]... meissner’s plexus

Microscopic Polyangiitis

(MPA) an autoimmune disease characterized by inflammation of small blood vessels, leading to reduced kidney function and breathlessness. It is associated with the presence of antinuclear cytoplasmic antibodies (*ANCA) and can be treated with corticosteroids, cyclophosphamide, or rituximab.... microscopic polyangiitis

Myocardial Perfusion Scan

(thallium scan) a method to detect and quantify myocardial *ischaemia. An intravenously injected *radionuclide that is taken up by normal heart muscle can be imaged using a *gamma camera. Areas of scar due to *myocardial infarction emit little or no radioactivity and are seen as ‘cold spots’. Exercise is mimicked by infusing drugs to increase the heart rate in order to provoke cold spots in the diagnosis of ischaemic heart disease.... myocardial perfusion scan

Myroxylon Pereirae

a fragrant resin used as a screener in patch testing for allergy to fragrance ingredients.... myroxylon pereirae

National Patient Safety Agency

(NPSA) formerly, a special health authority that led and coordinated work to improve all aspects of patient safety in England. The NPSA comprised three divisions: the National Reporting and Learning Service, the National Research Ethics Service, and the National Clinical Assessment Service. It closed in 2012, with its key functions transferred to *NHS England. In 2016 the same functions were transferred from NHS England to the newly formed *NHS Improvement.... national patient safety agency

Natriuretic Peptide

any of several peptides that stimulate diuresis (increased urine production) and vasodilatation (widening of blood vessels). They act on the kidney tubules to promote excretion of sodium (natriuresis) and water. Atrial natriuretic peptide (ANP) is produced in the atria of the heart in response to a rise in atrial pressure. Brain natriuretic peptide (BNP) is produced in the brain and the ventricles of the heart, mainly in response to stretching of the ventricular muscle (as occurs in congestive heart failure). Measurement of blood levels of BNP can be used as a diagnostic test for heart failure and also as an indicator of prognosis.... natriuretic peptide

Neural Plate

the strip of ectoderm lying along the central axis of the early embryo that forms the *neural tube and subsequently the central nervous system.... neural plate

Nhs Prescription Services Authority

(NHSPSA) see NHS Business Services Authority.... nhs prescription services authority

Niemann–pick Disease

an inherited (autosomal *recessive) disorder of lipid metabolism due to a defect in the enzyme sphingomyelinase and resulting in accumulation of sphingomyelin (a sphingolipid) and other phospholipids in the bone marrow, brain, liver, and spleen. Patients present with neurological problems, learning disabilities, and enlargement of the liver and spleen at a young age. There are four known types of the disease. [A. Niemann (1880–1921), German paediatrician; L. Pick (1868–1944), German pathologist]... niemann–pick disease

Noninvasive Prenatal Diagnosis

(NIPD) see prenatal diagnosis.... noninvasive prenatal diagnosis

Nonspecific Interstitial Pneumonia

(NSIP) see interstitial pneumonia.... nonspecific interstitial pneumonia

Nurse Practitioner

a registered nurse with advanced training and experience who assumes some of the duties and responsibilities formerly assumed only by a physician. Such nurses can practise in hospital or community settings within various domains of clinical activity, which may be condition-specific (e.g. diabetes, breast care), client-specific (e.g. children, the elderly, the homeless), or area-specific (e.g. general practice, dermatology).... nurse practitioner

Odontoid Process

a toothlike process from the upper surface of the axis vertebra. See cervical vertebrae.... odontoid process

Off-pump Cabg

*coronary artery bypass grafting (CABG) performed on a beating heart, i.e. without using *cardiopulmonary bypass (the pump refers to a *heart-lung machine).... off-pump cabg

Oncotic Pressure

a pressure represented by the pressure difference that exists between the osmotic pressure of blood and that of the lymph or tissue fluid. Oncotic pressure is important for regulating the flow of water between blood and tissue fluid. See also osmosis.... oncotic pressure

On–off Phenomenon

the rapid alternation between jerky uncontrolled movements (on) and very limited or no movement (off) most often seen in patients with Parkinson’s disease who have been undergoing long-term treatment with levodopa.... on–off phenomenon

Out-patient

n. a patient who receives treatment at a hospital, either at a single attendance or at a series of attendances, but is not admitted to a bed in a hospital ward. Large hospitals have *clinics at which out-patients with various complaints can be given specialist treatment. Compare in-patient.... out-patient

Pacchionian Body

see arachnoid villus. [A. Pacchioni (1665–1726), Italian anatomist]... pacchionian body

Pachy

combining form denoting 1. thickening of a part or parts. 2. the dura mater.... pachy

Pachydactyly

n. abnormal enlargement of the fingers and toes, occurring either as a congenital abnormality or as part of an acquired disease (such as *acromegaly).... pachydactyly

Pachyglossia

n. abnormal thickness of the tongue.... pachyglossia

Pachymeningitis

n. inflammation of the dura mater, one of the membranes (meninges) covering the brain and spinal cord (see meningitis).... pachymeningitis

Pachymeninx

n. the *dura mater, outermost of the three meninges.... pachymeninx

Pachymeter

n. an instrument used to measure the thickness of the cornea. —pachymetry n.... pachymeter

Pachyonychia Congenita

a rare genetically determined skin disorder (see genodermatosis) characterized by thickening of the nails together with other ectodermal abnormalities.... pachyonychia congenita

Pachysomia

n. thickening of parts of the body, which occurs in certain diseases.... pachysomia

Pachytene

n. the third stage of the first prophase of *meiosis, in which *crossing over begins.... pachytene

Pack

n. a pad of folded moistened material, such as cotton-wool, applied to the body or inserted into a cavity.... pack

Pack Years

a measure of a person’s cumulative cigarette consumption over a long period of time. It is expressed as the number of packs (assuming 20 cigarettes in a pack) smoked per day multiplied by the number of years of smoking:

For example, a patient who has smoked 15 cigarettes a day for 40 years has a (15/20) × 40 = 30 pack-year smoking history.... pack years

Paddington Alcohol Test

a three-question tool designed to uncover any connection between an individual’s attendance at an A & E department and alcohol-related problems, thereby creating the potential for intervention and referral.... paddington alcohol test

Paed

(paedo-) combining form denoting children.... paed

Paediatric Dentistry

the branch of dentistry concerned with the oral health care of children and adolescents.

Paediatric reference values... paediatric dentistry

Pain Clinic

a clinic that specializes in the management and relief of pain. Pain clinics are usually directed by anaesthetists.... pain clinic

Painful Bruising Syndrome

see Gardner–Diamond syndrome.... painful bruising syndrome

Paint

n. (in pharmacy) a liquid preparation that is applied to the skin or mucous membranes. Paints usually contain antiseptics, astringents, caustics, or analgesics.... paint

Palaeo

combining form denoting 1. ancient. 2. primitive.... palaeo

Palaeocerebellum

n. the anterior lobe of the cerebellum. In evolutionary terms it is one of the earliest parts of the hindbrain to develop in mammals.... palaeocerebellum

Palaeopathology

n. the study of the diseases of humans and other animals in prehistoric times, from examination of their bones or other remains. By examining the bones of specimens of Neanderthal man it has been discovered that spinal arthritis was a disease that existed at least 50,000 years ago.... palaeopathology

Palaeostriatum

n. see pallidum.... palaeostriatum

Palaeothalamus

n. the anterior and central part of the *thalamus, older in evolutionary terms than the lateral part, the neothalamus, which is well developed in apes and humans.... palaeothalamus

Palatal Myoclonus

rhythmical contraction of the palatal muscles. There are two forms, ordinary and essential. Ordinary palatal myoclonus is idiopathic and can result in *pulsatile tinnitus. Essential palatal myoclonus has no link to pulsatile tinnitus but may be associated with lesions of the brainstem.... palatal myoclonus

Palatine Bone

either of a pair of approximately L-shaped bones of the face that contribute to the hard *palate, the nasal cavity, and the orbits. See skull.... palatine bone

Palato

combining form denoting 1. the palate. 2. the palatine bone.... palato

Palatorrhaphy

n. see staphylorrhaphy.... palatorrhaphy

Pali

(palin-) combining form denoting repetition or recurrence.... pali

Paliphrasia

n. repetition of phrases while speaking: a form of *stammering or a kind of *tic.... paliphrasia

Pallidum

(palaeostriatum) n. one of the dense collections of grey matter, deep in each cerebral hemisphere, that go to make up the *basal ganglia.... pallidum

Palatoplasty

n. surgery to alter the shape or physical characteristics of the palate. This can be plastic surgery of the roof of the mouth, usually to correct cleft palate or other defects present at birth. Other palatoplasty operations are carried out under local or general anaesthesia to shorten and/or stiffen the palate in the treatment of snoring or obstructive sleep apnoea. They may use conventional surgical techniques (*uvulopalatopharyngoplasty), laser (*laser-assisted uvulopalatoplasty), insertion of stiffening materials, or injection of sclerosants. It is also possible to use radiofrequency energy in a process called radiofrequency palatal myoplasty (RPM), also known as somnoplasty.... palatoplasty

Pallium

n. the outer wall of the cerebral hemisphere as it appears in the early stages of evolution of the mammalian brain. In the modern brain it corresponds to the *cerebral cortex.... pallium

Palmar Erythema

reddening of the palms. This may be a variant of normal or a feature of pregnancy. It is also associated with chronic liver disease, connective tissue disease (such as rheumatoid arthritis), endocrine disorders (such as diabetes mellitus and thyrotoxicosis), certain infections, drugs, and smoking. There is no specific management for this condition.... palmar erythema

Palmer’s Point

an entry site for minimal-access surgery (see laparoscopy), especially when there is an increased risk from previous abdominal surgery. It is located in the left upper quadrant (see abdomen), 3 cm below the middle of the left costal margin. See Veress needle.... palmer’s point

Palmitic Acid

see fatty acid.... palmitic acid

Palmoplantar Erythrodysaesthesia

(hand–foot syndrome) a skin reaction marked by redness, numbness, and desquamation of the palms of the hands and soles of the feet. It can be caused by many chemotherapy drugs, particularly fluorouracil and capecitabine, and tyrosine kinase inhibitors. Treatment requires cessation of the drug.... palmoplantar erythrodysaesthesia

Pals

see Patient Advice and Liaison Service.... pals

Paludism

n. see malaria.... paludism

Pamidronate Disodium

a *bisphosphonate drug used to treat malignant *hypercalcaemia, breast cancer that has spread to the bones, and Paget’s disease. Side-effects include flulike symptoms, nausea, and vomiting.... pamidronate disodium

Pancoast Syndrome

pain and paralysis involving the lower branches of the brachial plexus due to infiltration by a malignant tumour of the apical region of the lung. *Horner’s syndrome may also be present. [H. K. Pancoast (1875–1939), US radiologist]... pancoast syndrome

Pancreas Divisum

a congenital abnormality in which the pancreas develops in two parts draining separately into the duodenum, the small ventral pancreas through the main ampulla and the larger dorsal pancreas through an accessory papilla. In rare instances this is associated with recurrent abdominal pain, probably due to inadequate drainage of the dorsal pancreas. Diagnosis is made by CT imaging, magnetic resonance cholangiopancreatography (MRCP), or *ERCP.... pancreas divisum

Pancreatic Enzyme Replacement Therapy

(PERT) a therapeutic approach using supplements of the digestive enzymes lipase, amylase, and protease (Creon, Pancrex), which are given when there is insufficient endogenous production of pancreatic enzymes: for example, to patients with pancreatic cancer or cystic fibrosis. The capsules must be taken with all meals and snacks to be effective. PERT treats the symptoms of *steatorrhoea.... pancreatic enzyme replacement therapy

Pancreatic Juice

the digestive juice secreted by the *pancreas. Its production is stimulated by hormones secreted by the duodenum, which in turn is stimulated by contact with food from the stomach. If the duodenum produces the hormone *secretin the pancreatic juice contains a large amount of sodium bicarbonate, which neutralizes the acidity of the stomach contents. Another hormone (see cholecystokinin) stimulates the production of a juice rich in digestive enzymes, including trypsinogen and chymotrypsinogen (which are converted to *trypsin and *chymotrypsin in the duodenum), *amylase, *lipase, and *maltase.... pancreatic juice

Pancreatic Polypeptide

a hormone released from the D cells of the *islets of Langerhans of the pancreas in response to protein in the small intestine. Its actions are to inhibit pancreatic bicarbonate and protein enzyme secretion and to relax the gall bladder. It belongs to a family of similar hormones that have actions on appetite and food metabolism.... pancreatic polypeptide

Pancreatogram

n. a radiographic image of the pancreatic ducts obtained by injecting contrast material into them by direct puncture under ultrasound guidance. It has largely been replaced by noninvasive techniques involving MRCP (see cholangiography).... pancreatogram

Pancreatotomy

n. surgical incision of the pancreatic duct to inspect the duct, to join the duct to the intestine, or to inject contrast material in order to obtain X-ray pictures of the duct system.... pancreatotomy

Pancreozymin

n. the name originally given to the fraction of the hormone *cholecystokinin that acts on the pancreas.... pancreozymin

Pancuronium

n. see muscle relaxant.... pancuronium

Panda Sign

a sign of bilateral periorbital *haematoma associated with injury to the anterior cranial fossa, the front of the skull cavity that supports the frontal lobes of the brain. The name derives from its similarity in appearance to the black eye patches of a panda.... panda sign

Panmixis

n. random mating within a population, i.e. when there is no selection of partners on religious, racial, social, or other grounds.... panmixis

Panniculus

n. a membranous sheet of tissue. For example, the panniculus adiposus is the fatty layer of tissue underlying the skin.... panniculus

Panophthalmitis

n. inflammation involving the whole of the interior of the eye.... panophthalmitis

Panstrongylus

n. a genus of large bloodsucking bugs (see reduviid). P. megistus is important in transmitting *Chagas’ disease to humans in Brazil.... panstrongylus

Pant

(panto-) combining form. see pan-.... pant

Pantaloon Hernia

a double sac comprising the sac of an indirect (external) and a direct (internal) inguinal *hernia on the same side.... pantaloon hernia

Panton–valentine Leukocidin

a cytotoxin responsible for increased virulence of *Staphylococcus aureus (see leukocidin). It may cause fatal necrotizing pneumonia or, more commonly, deep skin abscesses that tend to recur frequently. [Sir P. N. Panton (1877–1950) and F. C. Valentine (20th century), British pathologists]... panton–valentine leukocidin

Pantoprazole

n. see proton-pump inhibitor.... pantoprazole

Pantropic

adj. describing a virus that can invade and affect many different tissues of the body, for example the nerves, skin, or liver, without showing a special affinity for any one of them.... pantropic

Papillary

adj. nipple-like. Papillary epithelial neoplasms are composed of slender fronds of epithelial cells supported by fine fibrovascular cores. See papilloma.... papillary

Papillomatosis

n. a condition in which many *papillomas grow on an area of skin or mucous membrane.... papillomatosis

Papillotomy

n. the operation of cutting the *ampulla of Vater to widen its outlet in order to improve biliary drainage and allow the passage of stones from the common bile duct. It is usually performed using a diathermy wire through a *duodenoscope during *ERCP.... papillotomy

Papovavirus

n. one of a group of small DNA-containing viruses producing tumours in animals (subgroup polyomaviruses) and in animals and humans (subgroup papillomaviruses). See also human papillomavirus.... papovavirus

Papp-a

pregnancy-associated plasma protein A: a plasma protein in the serum of pregnant women that is used as a marker for Down’s syndrome (levels are decreased in comparison to normal pregnancies). Measurement of PAPP-A and *human chorionic gonadotrophin (hCG) can be combined in a *prenatal screening test during the first 12 weeks of pregnancy.... papp-a

Pappataci Fever

see sandfly fever.... pappataci fever

Papulo

combining form denoting a papule or pimple.... papulo

Papulosquamous

adj. describing a rash that is both papular and scaly.... papulosquamous

Paracoccidioides

n. a genus of yeast-like fungi causing infection of the skin and mucous membranes. The species P. brasiliensis causes a chronic skin disease, South American *blastomycosis.... paracoccidioides

Paracrine

adj. describing a hormone that is secreted by an endocrine gland and affects the function of nearby cells, rather than being transported distally by the blood or lymph.... paracrine

Paracusis

n. any distortion of hearing.... paracusis

Paradidymis

n. the vestigial remains of part of the embryonic *mesonephros that are found near the testis of the adult. Some of the mesonephric collecting tubules persist as the functional *vasa efferentia but the rest degenerate almost completely. A similar vestigial structure (the paroophoron) is found in females.... paradidymis

Paradox

n. (in *family therapy) a surprising interpretation or suggestion made in the course of therapy in order to demonstrate the relationship between a psychological symptom and a system of family relationships.... paradox

Paraffin

n. one of a series of hydrocarbons derived from petroleum. Paraffin wax (hard paraffin), a whitish mixture of solid hydrocarbons melting at 45–60°C, is used in medicine mainly as a base for ointments and in microscopy for *embedding specimens. Liquid paraffin is a mineral oil formerly used as a laxative; combined with soft paraffin (white or yellow), it is used as an emollient, as a lubricating ointment for treating dry eyes, and to impregnate gauze dressings to prevent the fibres from sticking.... paraffin

Paraganglioma

n. a tumour, related to *phaeochromocytoma, arising from *paraganglion cells. Such tumours can occur around the aorta, the carotid artery (carotid body tumour), and the cervical portion of the vagus nerve (*glomus tumour), as well as in the abdomen and the eye. They are usually benign and treated by surgery, but occasionally can be malignant, requiring systemic treatment.... paraganglioma

Parageusia

(parageusis) n. abnormality of the sense of taste.... parageusia

Paragonimus

n. a genus of large tropical parasitic *flukes that are particularly prevalent in the Far East. The adults of P. westermani live in the human lungs, where they cause destruction and bleeding of the tissues (see paragonimiasis). However, they may also be found in other organs of the body. Eggs are passed out in the sputum and the larvae undergo their development in two other hosts, a snail and a crab.... paragonimus

Paragranuloma

n. a former name for one of the types of *Hodgkin’s disease. It is now known as lymphocyte-predominant Hodgkin’s disease and has the best prognosis of all the types.... paragranuloma

Parainfluenza Viruses

a group of large RNA-containing viruses that cause infections of the respiratory tract producing mild influenza-like symptoms. They are included in the paramyxovirus group (see myxovirus).... parainfluenza viruses

Paramedian

adj. situated close to or beside the *median plane.... paramedian

Paramesonephric Duct

see Müllerian duct.... paramesonephric duct

Parametric Test

see significance.... parametric test

Parametritis

(pelvic cellulitis) n. inflammation of the loose connective tissue and smooth muscle around the uterus (the parametrium). The condition may be associated with *puerperal infection.... parametritis

Parametrium

n. the layer of connective tissue surrounding the uterus.... parametrium

Paramyotonia Congenita

a rare disorder in which prolonged contraction of muscle fibres (see myotonia) is precipitated by cold and exercise. It is due to a mutation in the sodium-channel gene.... paramyotonia congenita

Paramyxovirus

n. see myxovirus.... paramyxovirus

Paranasal Sinuses

the air-filled spaces, lined with mucous membrane, within some of the bones of the skull. They open into the nasal cavity, via the meatuses, and are named according to the bone in which they are situated. They comprise the frontal sinuses and the maxillary sinuses (one pair of each), the ethmoid sinuses (consisting of many spaces inside the ethmoid bone), and the two sphenoid sinuses. See illustration.... paranasal sinuses

Paraneoplastic Syndrome

signs or symptoms occurring in a patient with cancer that result from antibodies or *ectopic hormones produced by the cancer and are not due directly to local effects of the cancer cells. Examples are *myasthenia gravis secondary to a tumour of the thymus, a cerebellar syndrome in patients with lung cancer (due to anti-*Purkinje cell antibody), and a peripheral neuropathy in patients with breast cancer. Removal of the cancer usually leads to resolution of the problem.... paraneoplastic syndrome

Parapharyngeal Space

(lateral parapharyngeal space) the region at the side of the *pharynx. Infection in this space can result in a parapharyngeal abscess. It is also a site where tumours can develop.... parapharyngeal space

Paraprotein

n. an abnormal protein of the *immunoglobulin series. Paraproteins appear in malignant disease of the spleen, bone marrow, liver, etc. Examples of paraproteins are *myeloma globulins, *Bence-Jones protein, and *macroglobulin.... paraprotein

Parapsoriasis

n. an obsolete name for the earliest phase of *mycosis fungoides.... parapsoriasis

Parasternal

adj. situated close to the sternum. The parasternal line is an imaginary vertical line parallel to and midway between the lateral margin of the sternum and the vertical line through the nipple.... parasternal

Parastomal

adj. relating to the area around a *stoma, which often appears as a hernia or bulge. Following surgery, muscle structure is interrupted making it weaker and prone to stretching. Straining can cause intestinal contents to herniate through the weakened spot.... parastomal

Parasympatholytic

adj. opposing the effects of the *parasympathetic nervous system. *Antimuscarinic drugs have this effect by preventing acetylcholine from acting as a neurotransmitter.... parasympatholytic

Paratenon

n. the tissue of a tendon sheath that fills up spaces round the tendon.... paratenon

Parathormone

n. see parathyroid hormone.... parathormone

Parathyroidectomy

n. surgical removal of one or more of the *parathyroid glands, usually as part of the treatment of *hyperparathyroidism.... parathyroidectomy

Parathyroid Hormone

(parathormone) a hormone, synthesized and released by the parathyroid glands, that controls the distribution of calcium and phosphate in the body. A high level of the hormone causes transfer of calcium from the bones to the blood; a deficiency lowers blood calcium levels, causing *tetany. This condition may be treated by injections of calcium gluconate. Compare calcitonin.

Recombinant parathyroid hormone (Preotact) is given by subcutaneous injection to treat postmenopausal osteoporosis.... parathyroid hormone

Parathyroid Hormone-related Protein

(PTH-RP) a protein that is secreted by certain malignant tumours and is the main cause of malignant *hypercalcaemia. PTH-RP, which has effects similar to *parathyroid hormone, stimulates generalized bone resorption and excessive calcium reabsorption in the kidney tubules. It is most commonly produced by lung tumours, squamous-cell carcinomas of other organs, melanomas, and tumours of the breast, liver, pancreas, bladder, and prostate.... parathyroid hormone-related protein

Pareidolia

n. misperception of random stimuli as real things or people, as when faces are vividly seen in the flames of a fire.... pareidolia

Parental Order

see section 30 order.... parental order

Parental Responsibility

the legal status that requires adults to act in the interests of a child’s welfare. A birth mother always has parental responsibility unless it is removed by an adoption order, as has the father if married to the birth mother or named on the birth certificate. Same-sex parents, if civil partners, both have parental responsibility. In medical ethics, a person with parental responsibility can consent to, or refuse, treatment on behalf of a child who is too young to have capacity to make his or her own decisions about health care. However, the entitlement to act on behalf of a child is limited to the extent to which a person with parental responsibility is acting in the child’s best interests. See also Gillick competence.

UK government guidance on parental responsibility... parental responsibility

Paries

n. (pl. parietes) 1. the enveloping or surrounding part of an organ or other structure. 2. the wall of a cavity.... paries

Parietal Cells

(oxyntic cells) cells of the *gastric glands that secrete hydrochloric acid in the fundic region of the stomach.... parietal cells

Parliamentary And Health Service Ombudsman

(in England) an official responsible to Parliament and appointed to protect the interests of patients in relation to administration of and provision of health care by the *National Health Service. He or she can investigate complaints about the NHS when they cannot be resolved locally. In Scotland, and in Wales, this role is undertaken by a Public Services Ombudsman.... parliamentary and health service ombudsman

Paroophoron

n. the vestigial remains of part of the Wolffian duct (see mesonephros) in the female, situated next to each ovary. It is associated with a similar structure, the epoophoron. Both are without known function.... paroophoron

Parous

adj. having given birth to one or more children.... parous

Paroxysmal Nocturnal Haemoglobinuria

(PNH) a type of acquired haemolytic *anaemia that results from an abnormality of the red blood cell membrane. It is due to a defect in the formation of glycosylphosphatidylinositol (GPI), whose role is to anchor proteins to the lipid framework of the membrane. This leads to increased *complement-mediated destruction of red blood cells, which results in the release of haemoglobin in the circulation and then in the urine, giving the latter a reddish colour. Some patients may develop blood clots.... paroxysmal nocturnal haemoglobinuria

Parp Inhibitor

a drug that blocks the action of the PARP enzyme, which is required for *DNA repair in cancer cells with faulty *BRCA1 and BRCA2 genes. These drugs are used in the treatment of cancer in patients with BRCA1 or BRCA2 mutations. They are also undergoing trials to see if they are useful in the treatment of other cancers.... parp inhibitor

Pars

n. a specific part of an organ or other structure, such as any of parts of the pituitary gland.... pars

Pars Plana

part of the *uvea, one of the three layers that comprise the eye. As a part of the *ciliary body, it is about 4 mm long, located near the point where the iris and sclera touch, and is scalloped in appearance. It is a good site of entry for intraocular surgery.... pars plana

Part 2a Order

(in England) a legal order made by a magistrate on application by the local authority, in accordance with The Health Protection (Part 2A Orders) Regulations 2010, to exercise powers over a person, place, or thing that presents a risk to public health for a period of up to 28 days. Typically, fewer than ten such orders are issued annually. They may be used, for example, to detain an individual with infectious drug-resistant tuberculosis against their will in a setting with appropriate infection-control measures, or to seize equipment used by unregistered tattooists with poor infection-control practices.... part 2a order

Part Iii Accommodation

residential accommodation provided by local authorities, under the terms of Part III of the National Assistance Act 1948, for adults who, because of age, disability, illness, or any other reason, are in need of care and support.... part iii accommodation

Partial Volume Artifact

an apparent decrease in the visibility of a structure in a *cross-sectional imaging technique, such as CT or MRI, when either the thickness of the object is much less than that of the slice being used to make the image, or the object is only partially imaged within the slice. See artifact.... partial volume artifact

Participatory Action Research

(PAR) a radical approach to public health issues that actively involves communities in collaboration, reflection, data collection, and activities that empower them to improve their own health. See empowerment.... participatory action research

Particularism

n. a school of moral thought proposing that attention to the specifics and details of a situation is required to determine the preferred course of action. Such an approach is contrary to theories that depend on universal norms or principles, such as *Kantian ethics.... particularism

Parulis

n. see epulis.... parulis

Parvi

(parvo-) combining form denoting small size.... parvi

Pascal

n. the *SI unit of pressure, equal to 1 newton per square metre. Symbol: Pa.... pascal

Paschen Bodies

particles that occur in the cells of skin rashes in patients with *cowpox or *smallpox; they are thought to be the virus particles. [E. Paschen (1860–1936), German pathologist]... paschen bodies

Pasi

see psoriasis area severity index.... pasi

Passivity

n. (in psychiatry) a *Schneiderian first-rank symptom in which a patient has the impression that his or her feelings or actions are those of another or others, usually an unknown outside power.... passivity

Paste

n. (in pharmacy) a medicinal preparation of a soft sticky consistency, which is applied externally.... paste

Pastille

n. a medicinal preparation containing gelatine and glycerine, usually coated with sugar, that is dissolved in the mouth so that the medication is applied to the mouth or throat.... pastille

Patau Syndrome

a chromosome disorder in which there are three no. 13 chromosomes (instead of the usual two), causing abnormal brain development, severe learning disabilities, and defects in the heart, kidney, and scalp. Affected individuals rarely survive. [K. Patau (20th century), US geneticist]... patau syndrome

Patency

n. the relative openness or lack of obstruction in a tube or vessel, such as an artery or Fallopian tube.... patency

Patent Foramen Ovale

failure of the *foramen ovale to close shortly after birth resulting in an *atrial septal defect. A patent foramen ovale is present in everyone before birth but closes off in about 80% of people. It usually causes no symptoms; an isolated patent foramen ovale without any other structural heart defect is usually of no haemodynamic significance.... patent foramen ovale

Paternalism

n. an attitude or policy that overrides a person’s own wishes (*autonomy) in pursuit of his or her *best interests. The classic argument against paternalism of the philosopher John Stuart Mill is that intervention is justified only when trying to prevent a person from causing harm to others, not to himself. However, a form of paternalism may be justified when a person lacks the capacity to make decisions for him- or herself, assuming there is no valid *advance directive, decision, or statement or a proxy with *power of attorney to represent the patient’s wishes. See also therapeutic privilege. —paternalistic adj.... paternalism

Patellar Reflex

(knee jerk) reflex contraction of the quadriceps (thigh) muscle so that the leg kicks, elicited in a patient sitting with one knee crossed over the other by sharply tapping the tendon of the muscle below the kneecap. The reflex is mediated through nerves emanating from the third and fourth lumbar spinal levels (see spinal nerves). This is a test of the connection between the sensory nerves attached to stretch receptors in the muscle, the spinal cord, and the motor neurons running from the cord to the thigh muscle, all of which are involved in the reflex. The patellar reflex is reduced or absent when there is disease or damage of the spinal cord at or below the level of the reflex and exaggerated in disorders above the level of the reflex.... patellar reflex

Path

(patho-) combining form denoting disease. Example: pathophobia (morbid fear of).... path

Pathological Fracture

a fracture through diseased or abnormal bone, usually resulting from a force insufficient to fracture a normal bone. Tumour, infection, congenital bone defects, and osteoporosis are among the causes.... pathological fracture

Patient Advice And Liaison Service

(PALS) (in England) a confidential service provided by each NHS trust to support patients, their families, and carers by giving advice and information in response to questions and concerns about local NHS services. See also advocacy.... patient advice and liaison service

Patient Health Questionnaire

see PHQ-9.... patient health questionnaire

Patient Protection And Affordable Care Act

(PPACA) see Affordable Care Act 2010.... patient protection and affordable care act

Patulous

adj. open or distended. A patulous Eustachian tube is abnormally open. Air passing the nasal end of the tube sucks air from the middle ear. This creates symptoms including a flapping sensation, *autophony, and a paradoxical sensation that the ear is blocked.... patulous

Pauciarthritis

n. see arthritis.... pauciarthritis

Pavementation

(pavementing) n. the sticking of white blood cells to the linings of the finest blood vessels (capillaries) when inflammation occurs.... pavementation

Pca3

a gene that is expressed (i.e. manifests its effects) 60–100 times more in cancerous prostate tissue than in benign prostate tissue. A test for PCA3 can be performed on urine passed just after a digital rectal examination of the prostate; uPM3 – the first such test to be developed – is a far more specific indicator of the presence of prostate cancer than tests for *prostate specific antigen (PSA), increased amounts of which are produced in both malignant and nonmalignant prostate tissue. However, the test is not as sensitive as PSA in detecting the presence of prostate cancer.... pca3

Pcnl

see percutaneous nephrolithotomy.... pcnl

Pcos

see polycystic ovary syndrome.... pcos

Pdgf

platelet-derived growth factor (see growth factor).... pdgf

Peak Expiratory Flow Rate

(PEFR) the maximum rate at which a person can forcibly expel air from the lungs at any time, expressed usually in litres per minute (occasionally in litres per second). A low value can help diagnose asthma in the correct clinical context, and differences between the morning and evening values can also be a feature of poor control of asthma. There is a place for PEFR in the monitoring of acute exacerbations of chronic pulmonary obstructive disease (COPD) but not in the diagnosis of COPD.... peak expiratory flow rate

Peau D’orange

a dimpled appearance of the skin over a breast tumour, resembling the surface of an orange. The skin is thickened and the openings of hair follicles and sweat glands are enlarged.... peau d’orange

Pecten

n. 1. the middle section of the anal canal, below the anal valves (see anus). 2. a sharp ridge on the upper branch of the pubis (part of the hip bone). —pectineal adj.... pecten

Pectoral Girdle

see shoulder girdle.... pectoral girdle

Pectoral Muscles

the chest muscles (see illustration). The pectoralis major is a large fan-shaped muscle that works over the shoulder joint, drawing the arm forward across the chest and rotating it medially. Beneath it, the pectoralis minor depresses the shoulder and draws the scapula down towards the chest.... pectoral muscles

Pectus

n. the chest or breast.... pectus

Pectus Carinatum

see pigeon chest.... pectus carinatum

Pectus Excavatum

see funnel chest.... pectus excavatum

Pediculoides

(Pyemotes) n. a genus of widely distributed tiny predaceous mites. P. ventricosus occasionally attacks humans and causes an allergic dermatitis called grain itch. This complaint most usually affects those people coming into contact with stored cereal products, such as hay and grain.... pediculoides

Pediculus

n. a widely distributed genus of lice. There are two varieties of the species affecting humans: P. humanus capitis, the head louse; and P. humanus corporis, the body louse. The presence of these parasites can irritate the skin (see pediculosis), and in some parts of the world body lice are involved in transmitting *relapsing fever and *typhus.... pediculus

Pedometer

n. a small portable device that records the number of paces walked, and thus the approximate distance covered. A pedometer is usually attached to the leg or hung at the belt.... pedometer

Pedunculated

adj. having a stalk or stemlike attachment to an epithelial surface. Pedunculated tumours are commonly, but not invariably, benign.... pedunculated

Pefr

see peak expiratory flow rate.... pefr

Pegaptanib

n. see ranibizumab.... pegaptanib

Peginterferon Alfa

n. see interferon.... peginterferon alfa

Pegvisomant

n. see growth hormone.... pegvisomant

Pellicle

n. a thin layer of skin, membrane, or any other substance.... pellicle

Pelvic-floor Muscle Training

see Kegel exercises.... pelvic-floor muscle training

Pelvic Girdle

(hip girdle) the bony structure to which the bones of the lower limbs are attached. It consists of the right and left *hip bones.... pelvic girdle

Pemetrexed

n. an *antimetabolite used for treating pleural *mesothelioma and advanced *non-small-cell lung cancer. Side-effects include *myelosuppression, gastrointestinal symptoms, and skin disorders.... pemetrexed

Pemphigoid Gestationalis

(pemphigoid gestationis) a rare autoimmune condition (1 in 10,000–1 in 60,000 pregnancies) that usually starts in the second trimester with itching preceding a widespread *polymorphic eruption with vesicles and blisters. It is associated with *intrauterine growth restriction and preterm delivery.... pemphigoid gestationalis

Pena Operation

a recommended surgical treatment of congenital anal malformation.... pena operation

Pendred’s Syndrome

goitre associated with congenital deafness due to deficiency of *peroxidase, an enzyme that is essential for the utilization of iodine. [V. Pendred (1869–1946), British physician]... pendred’s syndrome

Penectomy

n. surgical removal of the penis, most commonly performed for penile cancer. It may be partial or total, depending on the degree of local tumour invasion.... penectomy

Penetrance

n. the frequency with which the characteristic controlled by a gene is seen in the individuals possessing it. Complete penetrance occurs when the characteristic is seen in all individuals known to possess the gene. If a percentage of individuals with the gene do not show its effects, penetrance is incomplete. In this way a characteristic in a family may appear to ‘skip’ a generation.... penetrance

Penicillium

n. a genus of mouldlike fungi that commonly grow on decaying fruit, bread, or cheese. The species P. rubrum is the major natural source of the antibiotic *penicillin. Some species of Penicillium are pathogenic to humans, causing diseases of the skin and respiratory tract.... penicillium

Penile Fracture

the traumatic rupture of the *tunica albuginea of the erect penis (the fibrous covering of the spongy tissue of the penis).... penile fracture

Penile Intraepithelial Neoplasia

(PIN) cellular changes affecting the glans, prepuce, or penile shaft that precede the invasive stages of cancer of the penis. There are three stages (PIN I, II, or III) based on the degree of *dysplasia. The pathological features of PIN III indicate *carcinoma in situ, known as *erythroplasia of Queyrat and Bowen’s disease.... penile intraepithelial neoplasia

Penile Pearly Papules

pale or skin-coloured papules that cluster around the corona of the glans penis in young uncircumcised men. They are asymptomatic but may be mistaken for viral warts.... penile pearly papules

Penile Prosthesis

see prosthesis.... penile prosthesis

Pent

(penta-) combining form denoting five.... pent

Pentose

n. a simple sugar with five carbon atoms: for example, ribose and xylose.... pentose

Pentostatin

n. a *cytotoxic drug that is used in treating *hairy cell leukaemia; it works by interfering with the action of the enzyme adenosine deaminase. Side-effects, which may be severe, include *myelosuppression.... pentostatin

Pentosuria

n. an inborn defect of sugar metabolism causing abnormal excretion of pentose in the urine. There are no serious ill-effects.... pentosuria

Pepsinogen

n. see pepsin.... pepsinogen

Peptidase

n. one of a group of digestive enzymes that split proteins in the stomach and intestine into their constituent amino acids. The group is divided into the *endopeptidases and *exopeptidases.... peptidase

Peptide Receptor Radionuclide Therapy

(PRRT) a type of radiotherapy used to treat neuroendocrine tumours (NETs; see neuroendocrine system). A *radionuclide is combined with a relevant *peptide to create a so-called radiopeptide, which is injected into the patient’s bloodstream. Because NETs have an overexpression of peptide receptors, the radiopeptide binds to the tumour, delivering a high dose of radiation directly to the cancer cells. The chief merit of PRRT is this ability to target delivery of radionuclides for highly localized treatment. A similar technique, using a gamma emitter as the radionuclide, can be used for locating and imaging NETs.... peptide receptor radionuclide therapy

Peptone

n. a large protein fragment produced by the action of enzymes on proteins in the first stages of protein digestion.... peptone

Peptonuria

n. the presence in the urine of *peptones, intermediate compounds formed during the digestion of proteins.... peptonuria

Percutaneous Coronary Intervention

(PCI) treatment of coronary artery disease delivered by cardiac *catheterization. This usually means *coronary angioplasty followed by insertion of a coronary *stent, but also includes more specialized procedures, such as rotational *atherectomy (rotablation). Primary PCI refers to the use of PCI as the first-line treatment to relieve coronary obstruction in S-T elevation *myocardial infarction, rather than *thrombolysis. Rescue PCI is used in the event of unsuccessful thrombolysis.... percutaneous coronary intervention

Percutaneous Epididymal Sperm Aspiration

see PESA.... percutaneous epididymal sperm aspiration

Percutaneous Nephrolithotomy

(PCNL) a technique of removing stones from the kidney via a *nephroscope passed into the kidney through a dilated track established from the skin surface into the renal pelvis.... percutaneous nephrolithotomy

Percutaneous Transhepatic Cholangiopancreatography

imaging of the bile duct and pancreatic duct. A catheter is carefully manipulated into the ducts via direct puncture through the abdomen under radiological guidance. Contrast material is flushed through the catheter to delineate the ducts (see also cholangiography). This procedure is often performed in cases of obstructive jaundice prior to insertion of a biliary drain or stent when *ERCP is not possible.... percutaneous transhepatic cholangiopancreatography

Performance Status

a scoring system used to quantify a patient’s activity level and general wellbeing in order to assess the patient’s suitability for chemotherapy or for taking part in a clinical trial. Commonly used systems include the WHO performance scale, scoring from 0 (fully active, feeling well) to 4 or 5 (very ill or near to death), and the Karnofsky scale, scoring from 0 (very ill) to 100 (feeling well).... performance status

Perforin

n. a protein produced by *cytotoxic T cells and *natural killer cells that are in contact with virus-infected target cells. It creates pores in the target-cell membrane, which facilitates the delivery of *granzymes to the cell to induce cell death (*apoptosis).... perforin

Pergolide

n. a drug that stimulates *dopamine receptors in the brain and is now rarely used in the treatment of Parkinson’s disease. Possible side-effects include confusion, hallucinations, sleepiness, heart irregularity, nausea, breathing difficulties, and double vision (see also bromocriptine).... pergolide

Periadenitis

n. inflammation of tissues surrounding a gland.... periadenitis

Periapical

adj. around an apex, particularly the apex of a tooth. The term is applied to bone surrounding the apex and to X-ray views of this area.... periapical

Perfusion Scan

a technique for demonstrating an abnormal blood supply to an organ by injecting a radioactive *tracer or *contrast medium. One of the most common uses, often in conjunction with ventilation scanning (see ventilation-perfusion scanning), is to detect obstruction of pulmonary arteries due to embolism by thrombus (see pulmonary embolism). Particles labelled with radioactive tracer are injected intravenously and become temporarily lodged in the capillaries in the lungs. Areas not being perfused show up as holes on the gamma-camera images. In *magnetic resonance imaging or *computerized tomography, contrast medium is injected and a series of images is obtained. The rate of change of enhancement is an index of the blood supply to the area of interest. This technique can be used to study blood supply to the brain, heart, or kidneys (in particular), to help diagnose arterial strictures or blockages, or tumours in which blood supply may be increased by abnormal vessels.... perfusion scan

Peri-arrest Period

the recognized period, either just before or just after a full *cardiac arrest, when the patient’s condition is very unstable and care must be taken to prevent progression or regression into a full cardiac arrest.... peri-arrest period

Periarthritis

n. inflammation of tissues around a joint capsule, including tendons and *bursae. Chronic periarthritis, which may be spontaneous or follow injury, is a common cause of pain and stiffness of the shoulder; it usually responds to local steroid injections or physiotherapy.... periarthritis

Periarticular

adj. around a joint, including the joint margins and surrounding area immediately adjacent to the joint capsule. The term is commonly used to specify fractures, tumours, and types of internal fixation devices. See also extra-articular; intra-articular.... periarticular

Peribulbar

adj. (in ophthalmology) denoting the area around the eyeball.... peribulbar

Pericard

(pericardio-) combining form denoting the pericardium.... pericard

Pericardiectomy

(pericardectomy) n. surgical removal of the membranous sac surrounding the heart (pericardium). It is used in the treatment of chronic constrictive pericarditis and chronic pericardial effusion (see pericarditis).... pericardiectomy

Pericardiocentesis

n. removal of excess fluid from within the sac (pericardium) surrounding the heart by means of needle *aspiration. See pericarditis; hydropericardium.... pericardiocentesis

Pericardiolysis

n. the surgical separation of *adhesions between the heart and surrounding structures within the ribcage (adherent pericardium). The operation has now fallen into disuse.... pericardiolysis

Pericardiorrhaphy

n. the repair of wounds in the membrane surrounding the heart (pericardium), such as those due to injury or surgery.... pericardiorrhaphy

Pericardiostomy

n. an operation in which the membranous sac around the heart is opened and the fluid within drained via a tube. It is sometimes used in the treatment of septic pericarditis.... pericardiostomy

Pericardiotomy

(pericardotomy) n. surgical opening or puncture of the membranous sac (pericardium) around the heart. It is required to gain access to the heart in heart surgery and to remove excess fluid from within the pericardium.... pericardiotomy

Pericardotomy

n. see pericardiotomy.... pericardotomy

Perichondrium

n. the dense layer of fibrous connective tissue that covers the surface of *cartilage.... perichondrium

Pericoronitis

n. inflammation of the gingivae around the crown of a tooth, particularly a partially erupted third molar.... pericoronitis

Pericranium

n. the *periosteum of the skull.... pericranium

Pericystitis

n. inflammation in the tissues around the bladder, causing pain in the pelvis, fever, and symptoms of *cystitis. It usually results from infection in the Fallopian tubes or uterus, but can occasionally arise from severe infection in a *diverticulum of the bladder itself. Treatment of pericystitis is directed to the underlying cause and usually involves antibiotic therapy. Pericystitis associated with a pelvic abscess clears when the abscess is surgically drained.... pericystitis

Periderm

n. see epitrichium.... periderm

Perihepatitis

n. inflammation of the membrane covering the liver (capsule). It is usually associated with abnormalities of the liver (including liver abscess, cirrhosis, tuberculosis) or chronic peritonitis.... perihepatitis

Perikaryon

n. see cell body.... perikaryon

Perilymph

n. the fluid between the bony and membranous *labyrinths of the ear.... perilymph

Perimenopause

n. the period of time around the *menopause in which marked changes in the menstrual cycle occur, usually accompanied by hot flushes, and in which no 12 consecutive months of *amenorrhoea have yet occurred.... perimenopause

Perimeter

n. an instrument for mapping the extent of the *visual field. The patient fixes his or her gaze on a target in the centre of the inner surface of the hemisphere. Objects are presented on this surface and the patient says if they can be seen. The area of the visual field can be defined and any gaps in the field can be detected. There are several types of perimeter. In the static perimeter the movable object is replaced by a system of tiny lights that can be flashed briefly. A patient with a field defect will fail to see the lights that flash in the area of the defect. Modern visual field testing uses computer-assisted automated perimeters to map out and analyse visual fields and thus detect very subtle field defects (computerized perimetry). Automated perimeters are commonly used in the diagnosis and follow-up of glaucoma. —perimetry n.... perimeter

Perimetrium

n. the *peritoneum of the uterus.... perimetrium

Perimysium

n. the fibrous sheath that surrounds each bundle of *muscle fibres.... perimysium

Perinatal Mortality Rate

(PNM) the total number of babies born dead after 24 weeks gestation (*stillbirths) and of live-born babies that die in the first week of life, regardless of gestational age at birth (early neonatal deaths), per 1000 live births and stillbirths. See infant mortality rate. See also confidential enquiries.... perinatal mortality rate

Perineal Descent

abnormal bulging down of the *perineum as a result of weakness of the pelvic floor muscles. It often accompanies problems with defecation and micturition.... perineal descent

Perineal Repair

see perineorrhaphy.... perineal repair

Perineal Tear

(perineal trauma) an injury to the perineum, which may be sustained during childbirth. Perineal tears can be classified by degree. First-degree tears involve the perineal skin and vaginal mucosa only. Second-degree tears involve the perineal muscles but not the anal sphincter. Third-degree tears involve the anal sphincter complex: the external anal sphincter (EAS) and internal anal sphincter (IAS). These are subclassified as 3a (less than 50% of EAS thickness torn), 3b (more than 50% of EAS thickness torn), and 3c (IAS torn). Fourth-degree tears involve the anal sphincter complex (EAS and IAS) and the anal epithelium or rectal mucosa. It is vitally important that these injuries are recognized and repaired by competent personnel. See also obstetric anal sphincter injury.... perineal tear

Perineoplasty

n. an operation designed to enlarge the vaginal opening by incising the hymen and part of the perineum (Fenton’s operation).... perineoplasty

Perineorrhaphy

n. the surgical repair of a damaged perineum. The damage is usually the result of a tear in the perineum sustained during childbirth (see perineal tear).... perineorrhaphy

Perinephric Abscess

a collection of pus around the kidney, usually secondary to *pyonephrosis but also resulting from spread of infection from other sites. It is more likely to occur in individuals who are immunosuppressed or have diabetes mellitus. Percutaneous or open surgical drainage are usually necessary but occasionally nephrectomy may be needed if the kidney is severely infected.... perinephric abscess

Perinephritis

n. inflammation of the tissues around the kidney. This is usually due to spread of infection from the kidney itself (see pyelonephritis; pyonephrosis). The patient has pain in the loins, fever, and fits of shivering. Prompt treatment of the underlying renal infection is required to prevent progression to an abscess.... perinephritis

Perineurium

n. the sheath of connective tissue that surrounds individual bundles (fascicles) of nerve fibres within a large *nerve.... perineurium

Periocular

adj. adjacent to the eyeball.... periocular

Periodic Acid–schiff Reaction

(PAS reaction) a test for the presence of glycoproteins, polysaccharides, certain mucopolysaccharides, glycolipids, and certain fatty acids in tissue sections. The tissue is treated with periodic acid, followed by *Schiff’s reagent. A positive reaction is the development of a red or magenta coloration.... periodic acid–schiff reaction

Periodontal Abscess

a localized abscess that arises in the periodontal tissues and is usually an acute manifestation of periodontal disease. It appears as a pocket of pus in the tissues of the gum but not around the apex of the tooth.... periodontal abscess

Periodontal Pocket

a space between the gingival tissues and tooth occurring in periodontitis. See periodontal disease.... periodontal pocket

Periodontium

n. the tissues that support and attach the teeth to the jaw: the gums (see gingiva), *periodontal membrane, alveolar bone, and *cementum.... periodontium

Periodontology

n. the branch of dentistry concerned with the tissues that support and attach the teeth and the prevention and treatment of *periodontal disease.... periodontology

Perioperative

adj. denoting the period that extends from the day before to the first few days after surgery, during which drugs (e.g. analgesics, antibiotics, anticoagulants) may need to be administered and *vital signs are monitored.... perioperative

Periorbital

adj. 1. around the eye socket (*orbit). 2. relating to the periosteum within the orbit.... periorbital

Periotome

n. a sharp instrument used in dental extractions. It is used to sever the periodontal ligament, thereby enabling an atraumatic extraction with minimal damage to the bony and soft tissue architecture.... periotome

Peripheral Neuropathy

(polyneuropathy, peripheral neuritis) any of a group of disorders affecting the sensory and/or motor nerves in the peripheral nervous system. They tend to start distally, in the fingers and toes, and progress proximally. Symptoms include pins and needles, stabbing pains and a numbness on the sensory side, and weakness of the muscles. The most common causes of peripheral neuropathy are diabetes, alcohol, certain drugs, and such infections as HIV; genetic causes of peripheral neuropathy include amyloidosis and *Charcot-Marie-Tooth disease. The diagnosis may be established by neurophysiological tests, blood tests, and occasionally a nerve biopsy.... peripheral neuropathy

Peripheral Parenteral Nutrition

(PPN) the delivery of nutrients directly into a peripheral vein (in the arm). Feed solutions must have a low *osmolality (<1200 mOsm/l), and PPN can be given only for a short period (less than four weeks). There is a risk of *phlebitis. See artificial nutrition and hydration; total parenteral nutrition.... peripheral parenteral nutrition

Periphlebitis

n. inflammation of the tissues around a vein: seen as an extension of *phlebitis.... periphlebitis

Perisalpingitis

n. inflammation of the peritoneal membrane on the outer surface of a Fallopian tube.... perisalpingitis

Perisplenitis

n. inflammation of the external coverings of the spleen.... perisplenitis

Peritendineum

n. the fibrous covering of a tendon.... peritendineum

Peritendinitis

n. see tenosynovitis.... peritendinitis

Peritomy

n. an eye operation in which an incision of the conjunctiva is made in a complete circle around the cornea.... peritomy

Peritoneoscope

n. see laparoscope.... peritoneoscope

Peritrichous

adj. describing bacteria in which the flagella cover the entire cell surface.... peritrichous

Perityphlitis

n. Archaic. inflammation of the tissues around the caecum.... perityphlitis

Periureteritis

n. inflammation of the tissues around a ureter. This is usually associated with inflammation of the ureter itself (*ureteritis) often behind an obstruction caused by a stone or stricture. Treatment is directed to relieving any obstruction of the ureter and controlling the infection with antibiotics.... periureteritis

Periurethral Injection

the injection of a bulking agent (e.g. collagen) into the tissues around the urethra, used for the treatment of urodynamic stress *incontinence. Such injections have a low morbidity and are easy to administer, and results are better in women with good bladder-neck support but poor urethral function. The short-term success rates of these procedures are reasonable, but long-term success rates are poor.... periurethral injection

Perivascular Spaces

see Virchow–Robin spaces.... perivascular spaces

Periventricular Haemorrhage

(PVH) a significant cause of morbidity and mortality in infants who are born prematurely in which bleeding occurs from fragile blood vessels around the *ventricles in the brain. Bleeding extending into the lateral ventricles is termed intraventricular haemorrhage (IVH) and in severe cases can extend into the brain tissue (cerebral parenchyma). Surviving infants may have long-term neurological deficits, such as cerebral palsy, developmental delay, or seizures.... periventricular haemorrhage

Periventricular Leucomalacia

(PVL) softening of white matter around the ventricles of the brain in preterm infants due to a decreased blood supply to the brain, usually associated with *hypoxic-ischaemic encephalopathy. Diagnosis is by ultrasound, which shows increased density and, later, cysts in the periventricular area. The brain damage can cause visual impairment and cerebral palsy.... periventricular leucomalacia

Perle

n. a soft capsule containing medicine.... perle

Perleche

n. dryness and cracking of the corners of the mouth, sometimes with infection. Perleche may be caused by persistent lip licking or by a vitamin-deficient diet.... perleche

Pernicious

adj. describing diseases that are highly dangerous or likely to result in death if untreated. See also pernicious anaemia.... pernicious

Perniosis

n. see chilblains.... perniosis

Pero

combining form denoting deformity; defect. Example: peromelia (of the limbs).... pero

Peroneus

n. one of the muscles of the leg that arises from the fibula. The peroneus longus and peroneus brevis are situated at the side of the leg and inserted into the metatarsal bones of the foot. They help to turn the foot outwards.... peroneus

Peroxidase

n. an enzyme, found mainly in plants but also present in leucocytes and milk, that catalyses the dehydrogenation (oxidation) of various substances in the presence of hydrogen peroxide (which acts as a hydrogen acceptor, being converted to water in the process).... peroxidase

Peroxisome

n. a small structure within a cell that is similar to a *lysosome but contains different enzymes, some of which may take part in reactions involving hydrogen peroxide.... peroxisome

Persistent Idiopathic Facial Pain

(atypical facial pain, chronic idiopathic facial pain) a chronic pain in the face that has no known cause and does not fit the classic presentation of other cranial neuralgias. It may be stress-related, and in some cases appears to be associated with defective metabolism of *tyramine. Treatment may involve the use of antidepressants.... persistent idiopathic facial pain

Personal Independence Payment

(PIP) a tax-free benefit replacing (from April 2013) *disability living allowance (DLA) for people aged 16–64 (DLA is still paid to children). It has two components – a daily living component (including help with washing, dressing, using the toilet, preparing and eating food, and taking medicines) and a mobility component (for help with walking).... personal independence payment

Person-centred Care

an approach to health care that focuses on the needs of the individual care user, rather than providing a standardized response to their condition. The patient is encouraged to take an active role in discussing a health-care plan that reflects their own needs, circumstances, and values.... person-centred care

Personhood

n. a philosophical concept designed to determine which individuals have human rights and responsibilities. Personhood may be distinguished by possession of defining characteristics, such as consciousness and rationality, or in terms of relationships with others. Philosophers disagree on whether all humans are, or all nonhuman animals are not, persons, especially when debating the ethics of abortion, euthanasia, and human uses of animals. In law, corporations can be regarded as having personhood, when identifying their rights and responsibilities.... personhood

Pert

see pancreatic enzyme replacement therapy.... pert

Pesa

(percutaneous epididymal sperm aspiration) a method of assisted conception in which spermatozoa are removed directly from the *epididymis under local anaesthetic. The sperm are then used to fertilize egg cells in vitro (see ICSI).... pesa

Pesticide

n. a chemical agent used to kill insects or other organisms harmful to crops and other cultivated plants. Some pesticides, such as *parathion and *dieldrin, have caused poisoning in human beings and livestock after accidental exposure.... pesticide

Pethidine

n. a potent opioid analgesic (see opiate) with mild sedative action, used to relieve moderate or severe pain of short duration (including that associated with childbirth). Side-effects may include nausea, dizziness, and dry mouth.... pethidine

Petri Dish

a flat shallow circular glass or plastic dish with a pillbox-like lid, used to hold solid agar or gelatin media for culturing bacteria. [J. R. Petri (1852–1921), German bacteriologist]... petri dish

Petrissage

n. kneading: a form of *massage in which the skin is lifted up, pressed down and squeezed, and pinched and rolled. Alternate squeezing and relaxation of the tissues stimulates the local circulation and may have a pain-relieving effect in muscular disorders.... petrissage

Petrositis

n. inflammation of the petrous part of the *temporal bone (which encloses the inner ear), usually due to an extension of *mastoiditis.... petrositis

Petrous Bone

see temporal bone.... petrous bone

Peutz–jeghers Syndrome

a hereditary disorder in which the presence of multiple *polyps in the lining of the small intestine (intestinal *polyposis) is associated with pigmented areas (similar to freckles) around the lips, on the inside of the mouth, and on the palms and soles. The polyps can also occur in the colon and stomach. They may bleed, resulting in anaemia, or may cause obstruction of the bowel. Half of the patients develop malignant tumours (not necessarily of the bowel). [J. L. A. Peutz (1886–1957), Dutch physician; H. J. Jeghers (1904–90), US physician]... peutz–jeghers syndrome

Pexy

combining form denoting surgical fixation. Example: omentopexy (of the omentum).... pexy

Peyer’s Patches

oval masses of *lymphoid tissue on the mucous membrane lining the small intestine. [J. C. Peyer (1653–1712), Swiss anatomist]... peyer’s patches

Phaco

(phako-) combining form denoting the lens of the eye.... phaco

Phacodonesis

n. tremulousness of the lens seen when the eye moves from side to side as a result of partial dislocation of the lens, as can occur after trauma or in *Marfan’s syndrome.... phacodonesis

Phacoemulsification

(phakoemulsification) n. the use of a high-frequency *ultrasound probe to break up a cataract so that it can be removed through a very small incision. This is now the most popular method of performing cataract surgery in the developed world.... phacoemulsification

Phag

(phago-) combining form denoting 1. eating. 2. phagocytes.... phag

Phage

n. see bacteriophage.... phage

Phagia

combining form denoting a condition involving eating.... phagia

Phakic

adj. denoting an eye with the natural crystalline lens still in place, as contrasted with aphakic (see aphakia) or pseudophakic (see pseudophakia).... phakic

Phako

combining form. see phaco-.... phako

Phalangeal Cells

rows of supporting cells between the sensory hair cells of the organ of Corti (see cochlea).... phalangeal cells

Phalangectomy

n. surgical removal of one or more of the small bones (phalanges) in the fingers or toes.... phalangectomy

Phalangitis

n. inflammation of a finger or toe, causing swelling and pain. The condition may be caused by infection of the soft tissues, tendon sheaths, bone, or joints or by some rheumatic diseases, such as *psoriatic arthritis. See also dactylitis.... phalangitis

Phalen’s Sign

a diagnostic sign for *carpal tunnel syndrome. The patient is asked to hold his or her wrists in full flexion with the dorsal surfaces of both hands pushing against each other with fingers pointing downwards for 30–60 seconds. This manoeuvre increases pressure on the median nerve: tingling and numbness or pain in the thumb, index, middle, and ring fingers suggests carpal tunnel syndrome. See also Tinel’s sign. [G. S. Phalen (1911–98), US orthopaedist]... phalen’s sign

Phalloplasty

n. surgical reconstruction or repair of the penis. It is required for congenital deformity of the penis, as in *hypospadias or *epispadias, and sometimes also following injury to the penis with loss of skin.... phalloplasty

Phanero

combining form denoting visible; apparent.... phanero

Phantom Pregnancy

see pseudocyesis.... phantom pregnancy

Phantom Tumour

1. an accumulation of fluid (pleural effusion) in the lung in patients with heart failure, which resembles a lung tumour on radiological examination. 2. a swelling in the abdomen or elsewhere, caused by local muscular contraction or the accumulation of gases, that mimics a swelling caused by a tumour.... phantom tumour

Pharmacist

n. a person who is qualified by examination and registered and authorized to dispense medicines or to keep open a shop for the sale and dispensing of medicines.... pharmacist

Pharmaco

combining form denoting drugs. Example: pharmacophobia (morbid fear of).... pharmaco

Pharmacodynamics

n. the interaction of drugs with cells. It includes such factors as the binding of drugs to cells, their uptake, and intracellular metabolism.... pharmacodynamics

Pharyng

(pharyngo-) combining form denoting the pharynx. Example: pharyngopathy (disease of).... pharyng

Pharyngeal Arch

(branchial arch, visceral arch) any of the paired segmented ridges of tissue in each side of the throat of the early embryo that correspond to the gill arches of fish. Each arch contains a cartilage, a cranial nerve, and a blood vessel. Between each arch there is a *pharyngeal pouch.... pharyngeal arch

Pharyngeal Cleft

(branchial cleft, visceral cleft) any of the paired segmented clefts in each side of the throat of the early embryo that correspond to the gills of fish. Soon after they have formed they close to form the *pharyngeal pouches, except for the first cleft, which persists as the external auditory meatus.... pharyngeal cleft

Pharyngeal Reflex

see gag reflex.... pharyngeal reflex

Pharyngectomy

n. surgical removal of part of the pharynx.... pharyngectomy

Pharyngocele

n. a pouch or cyst opening off the pharynx (see branchial cyst).... pharyngocele

Pharyngoscope

n. an *endoscope for the examination of the pharynx.... pharyngoscope

Phentolamine

n. a drug that dilates blood vessels (see alpha blocker) and is used to reduce high blood pressure in patients with *phaeochromocytoma. Side-effects include fast heartbeat and digestive upsets.... phentolamine

Phenylthiocarbamide

(PTC) n. a substance that tastes bitter to some individuals but is tasteless to others. Response to PTC appears to be controlled by a single pair of genes (*alleles): ability to taste PTC is *dominant to the inability to taste it.... phenylthiocarbamide

Phial

n. a small glass bottle for storing medicines or poisons.... phial

Philadelphia Chromosome

an abnormal form of chromosome 22 that has a foreshortened long arm due to a reciprocal *translocation with chromosome 9. It is most commonly seen in the marrow cells of patients with chronic *myeloid leukaemia.... philadelphia chromosome

Philia

combining form denoting morbid craving or attraction. Example: nyctophilia (for darkness).... philia

Phleb

(phlebo-) combining form denoting a vein or veins. Example: phlebectopia (abnormal position of).... phleb

Phlebectomy

n. the surgical removal of a vein (or part of a vein), sometimes performed for the treatment of varicose veins in the legs (varicectomy).... phlebectomy

Phlebosclerosis

(venosclerosis) n. a rare degenerative condition, of unknown cause, that affects the leg veins of young men. The vein walls become thickened and feel like cords under the skin. It is not related to arteriosclerosis and needs no treatment.... phlebosclerosis

Phlebothrombosis

n. obstruction of a vein by a blood clot, without preceding inflammation of its wall. It is most common within the deep veins of the calf of the leg – deep vein thrombosis (DVT) – in contrast to *thrombophlebitis, which affects superficial leg veins. Prolonged immobility, heart failure, pregnancy, injury, and surgery predispose to thrombosis by encouraging sluggish blood flow. Many of these conditions are associated with changes in the clotting factors in the blood that increase the tendency to thrombosis; these changes also occur in some women taking oral contraceptives.

The affected leg may become swollen and tender. The main danger is that the clot may become detached and give rise to *pulmonary embolism. Regular leg exercises help to prevent deep vein thrombosis, and anticoagulant drugs (such as heparin and warfarin) are used in prevention and treatment. Large clots may be removed surgically in the operation of thrombectomy to relieve leg swelling.... phlebothrombosis

Phlebotomus

n. see sandfly.... phlebotomus

Phlegmon

n. Archaic. inflammation of connective tissue, leading to ulceration.... phlegmon

Phlycten

n. a small pinkish-yellow nodule surrounded by a zone of dilated blood vessels that occurs in the conjunctiva or in the cornea. It develops into a small ulcer that heals without trace in the conjunctiva but produces some residual scarring in the cornea. Phlyctens, which are prone to recur, are thought to be due to a type of allergy to certain bacteria.... phlycten

Phonasthenia

n. weakness of the voice, especially when due to fatigue.... phonasthenia

Phoniatrics

n. the study of the voice and its disorders.... phoniatrics

Phonocardiogram

n. see electrocardiophonography. —phonocardiography n.... phonocardiogram

Phonophobia

n. excessive sensitivity to and fear of certain specific sounds irrespective of the level of the sound. See hyperacusis; misophonia.... phonophobia

Phonosurgery

n. surgery performed on the larynx externally or endoscopically to improve or modify the quality of the voice.... phonosurgery

Phoria

combining form denoting (in ophthalmology) an abnormal deviation of the eyes or turning of the visual axis. Example: heterophoria (tendency to squint).... phoria

Phormia

n. a genus of non-bloodsucking flies, commonly known as blowflies. The maggot of P. regina normally breeds in decaying meat but it has occasionally been found in suppurating wounds, giving rise to a type of *myiasis.... phormia

Phosgene

n. a poisonous gas developed during World War I. It is a choking agent, acting on the lungs to produce *oedema, with consequent respiratory and cardiac failure.... phosgene

Phosphagen

n. creatine phosphate (see creatine).... phosphagen

Phosphataemia

n. the presence of phosphates in the blood. Sodium, calcium, potassium, and magnesium phosphates are normal constituents.... phosphataemia

Phosphatase

n. one of a group of enzymes capable of catalysing the hydrolysis of phosphoric acid esters. An example is glucose-6-phosphatase, which catalyses the hydrolysis of glucose-6-phosphate to glucose and phosphate. Phosphatases are important in the absorption and metabolism of carbohydrates, nucleotides, and phospholipids and are essential in the calcification of bone. Acid phosphatase is present in kidney, semen, serum, and the prostate gland. Alkaline phosphatase occurs in teeth, developing bone, plasma, kidney, and intestine.... phosphatase

Phosphatidylcholine

n. see lecithin.... phosphatidylcholine

Phosphatidylserine

n. a cephalin-like phospholipid containing the amino acid serine. It is found in brain tissue. See also cephalin.... phosphatidylserine

Phosphocreatine

n. creatine phosphate (see creatine).... phosphocreatine

Phosphofructokinase

n. an enzyme that catalyses the conversion of fructose-6-phosphate to fructose-1,6-diphosphate. This is an important reaction occurring during the process of *glycolysis.... phosphofructokinase

Phosphonecrosis

n. the destruction of tissues caused by excessive amounts of phosphorus in the system. The tissues likely to suffer in phosphorus poisoning are the liver, kidneys, muscles, bones, and the cardiovascular system.... phosphonecrosis

Phosphorylase

n. any enzyme that catalyses the combination of an organic molecule (usually glucose) with a phosphate group (phosphorylation). Phosphorylase is found in the liver and kidney, where it is involved in the breakdown of glycogen to glucose-1-phosphate.... phosphorylase

Phot

(photo-) combining form denoting light.... phot

Photalgia

n. pain in the eye caused by very bright light.... photalgia

Photoablation

n. the use of light or lasers to destroy tissue.... photoablation

Photodermatosis

n. any of various skin diseases caused by exposure to light of varying wavelength (see photosensitivity). The facial prominences and the ‘V’ of the neck are most commonly affected, the shadow areas behind the ears and below the chin being protected. A common photodermatosis is polymorphous light eruption, which affects 10% of the population. It appears with the first sunshine of spring and abates by late summer. The photodermatoses include certain *porphyrias, notably porphyria cutanea tarda.... photodermatosis

Photodynamic Diagnosis

a technique for improving the sensitivity and specificity of bladder cancer diagnosis at cystoscopy using a light-sensitive agent. This agent is instilled into the bladder, taken up by the epithelial cells, and converted into a porphyrin that accumulates only in malignant and premalignant cells. It fluoresces under light of a specific wavelength and is thus highlighted against normal bladder mucosa.... photodynamic diagnosis

Photomicrograph

n. an enlarged photographic record of an object taken through an optical or electron microscope. Compare microphotograph.... photomicrograph

Photomultiplier Tube

an electronic device that magnifies the light emitted from a *scintillator by accelerating electrons in a high-voltage field. The resulting signal can be used to display the scintillations on a TV screen. Such devices are commonly used in *gamma cameras.... photomultiplier tube

Photophthalmia

n. inflammation of the eye due to exposure to light. It is usually caused by the damaging effect of ultraviolet light on the cornea, for example in snow blindness or when lying under a sunbed.... photophthalmia

Photopic

adj. relating to or describing conditions of bright illumination. For example, photopic vision is vision in bright light, in which the *cones of the retina are responsible for visual sensation. —photopia n.... photopic

Photoradiation

n. see photodynamic therapy.... photoradiation

Photoretinitis

n. damage to the retina of the eye caused by looking at the sun without adequate protection for the eyes. The retina may be burnt by the intense light focused on it; this affects the central part of the visual field, which may be permanently lost (sun blindness).... photoretinitis

Photoselective Vaporization Of The Prostate

(PVP) a technique to vaporize the prostate by means of a high-energy laser, used to relieve *lower urinary tract symptoms due to benign prostatic hyperplasia (see prostate gland). It is associated with less blood loss and a shorter hospital stay than a traditional TURP (see resection), but can only be used on smaller prostates.... photoselective vaporization of the prostate

Phototaxis

n. movement of a cell or organism in response to a stimulus of light.... phototaxis

Phototherapeutic Keratectomy

see keratectomy.... phototherapeutic keratectomy

Phototoxicity

n. damage caused by prolonged exposure to light; for example, retinal phototoxicity is damage to the retina of the eye as a result of prolonged exposure to light.... phototoxicity

Photuria

n. the excretion of phosphorescent urine, which glows in the dark, due to the presence of certain phosphorus-containing compounds derived from phosphates.... photuria

Phren

(phreno-) combining form denoting 1. the mind or brain. 2. the diaphragm. 3. the phrenic nerve.... phren

Phrenia

combining form denoting a condition of the mind. Example: hebephrenia (schizophrenia affecting young adults).... phrenia

Phrenic Crush

1. damage to the phrenic nerve as a result of trauma. 2. formerly, surgical crushing of a portion of the *phrenic nerve. This paralyses the diaphragm on the side operated upon, which is then pushed upwards by the abdominal contents, thus pressing on the lung and partially collapsing it. This operation was formerly often combined with *pneumoperitoneum in the treatment of pulmonary tuberculosis but is now obsolete.... phrenic crush

Phrygian Cap

the normal radiological appearance of the tip of the gall bladder, seen in a minority of cholecystograms (see cholecystography). Its name is derived from its resemblance to the characteristic Balkan headgear.... phrygian cap

Phthirus

n. a widely distributed genus of lice. The crab (or pubic) louse, P. pubis, is a common parasite of humans that lives permanently attached to the body hair, particularly that of the pubic or perianal regions but also on the eyelashes and the hairs in the armpits. Crab lice are not known to transmit disease but their bites can irritate the skin (see pediculosis). An infestation may be acquired during sexual intercourse or from hairs left on clothing, towels, and lavatory seats.... phthirus

Phycomycosis

n. a disease caused by parasitic fungi of the genera Rhizopus, Absidia, and Mucor. The disease affects the sinuses, the central nervous system, the lungs, and the skin tissues. The fungi are able to grow within the blood vessels of the lungs and nervous tissue, thus causing blood clots which cut off the blood supply (see infarction). Treatment with the antibiotic *amphotericin has proved effective.... phycomycosis

Phylogenesis

n. the evolutionary history of a species or individual.... phylogenesis

Physi

(physio-) combining form denoting 1. physiology. 2. physical.... physi

Physical

adj. (in medicine) relating to the body rather than to the mind. For example, a physical sign is one that a doctor can detect when examining a patient, such as abnormal dilation of the pupils or the absence of a knee-jerk reflex (see also functional disorder; organic disorder).... physical

Physiological Saline

see saline.... physiological saline

Physiological Solution

one of a group of solutions used to maintain tissues in a viable state. These solutions contain specific concentrations of substances that are vital for normal tissue function (e.g. sodium, potassium, calcium, chloride, magnesium, bicarbonate, and phosphate ions, glucose, and oxygen). An example of such a solution is *Ringer’s solution.... physiological solution

Physis

(growth plate) a horizontal band of tissue located between the ends (*epiphyses) of a long bone and the growing zone (*metaphysis) of the shaft. It is composed of cartilaginous, bony, and fibrous components that combine to allow for longitudinal and latitudinal growth and remodelling of the developing bone (endochondral *ossification). See also Salter-Harris classification.

physo- combining form denoting air or gas.... physis

Phyt

(phyto-) combining form denoting plants; of plant origin.... phyt

Phytochemical

n. one of a large group of non-nutritive compounds made by plants that have an effect on health. They include *antioxidants, flavonoids, flavanols, flavanones, isoflavones, anthocyanins, carotenoids, polyphenols, phenolic acids, phyto-oestogens, and others.... phytochemical

Phytohaemagglutinin

(PHA) n. a plant-derived alkaloid that stimulates T lymphocytes to divide in the test tube.... phytohaemagglutinin

Phytophotodermatitis

n. an eruption of linear blisters occurring after exposure to light in people who have been in contact with certain plants, such as wild parsnip or cow parsley, to which they are sensitive. A particularly dramatic reaction occurs with giant hogweed (Heracleum mantegazzianum). The skin often appears brown as the blisters resolve.... phytophotodermatitis

Phytotoxin

n. any poisonous substance (toxin) produced by a plant, such as any of the toxins produced by fungi of the genus *Amanita.... phytotoxin

Picc Line

peripherally inserted central catheter: a long flexible catheter usually inserted via a vein in the arm and the subclavian vein into the superior vena cava. It is used when prolonged intravenous access is required; for example, for infusional chemotherapy and *total parenteral nutrition (TPN).... picc line

Pick’s Disease

see frontotemporal dementia. [A. Pick (1851–1924), Czech psychiatrist]... pick’s disease

Pico

prefix denoting one million-millionth (10?12).... pico

Picornavirus

n. one of a group of small RNA-containing viruses (pico = small; hence pico-RNA-virus). The group includes *Coxsackie viruses, *polioviruses, and *rhinoviruses.... picornavirus

Picture Archiving And Communication System

see PACS.... picture archiving and communication system

Picu

(psychiatric intensive care unit) a unit especially designed for nursing the most acutely and severely mentally ill. PICUs are often locked wards with increased staffing levels. Usually patients stay on a PICU ward for the shortest possible period before being transferred to an open psychiatric ward.... picu

Pierre Robin Syndrome

a congenital disease in which affected infants have a very small lower jawbone (mandible) and a cleft palate. They are susceptible to feeding and respiratory problems. [Pierre Robin (1867–1950), French dentist]... pierre robin syndrome

Piezoelectric

adj. denoting or relating to an electrically generated pulse or polarity that is caused by pressure.... piezoelectric

Pigeon Chest

forward protrusion of the breastbone resulting in deformity of the chest. The condition is painless and harmless. Medical name: pectus carinatum.... pigeon chest

Pigeon Toe

see in-toe gait.... pigeon toe

Pigment Epitheliopathy

an inflammatory disease of the retinal pigment epithelium (RPE; see retina). Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is characterized by the presence of multiple cream-coloured irregular lesions scattered in the posterior segment of the eye. The disease occurs in young adults and usually affects both eyes. Visual acuity usually recovers with time.... pigment epitheliopathy

Pill

n. 1. a small ball of variable size, shape, and colour, sometimes coated with sugar, that contains one or more medicinal substances in solid form. It is taken by mouth. 2. see oral contraceptive.... pill

Pillar

n. (in anatomy) an elongated apparently supportive structure. For example, the pillars of the fauces are folds of mucous membrane on either side of the opening from the mouth to the pharynx.... pillar

Pilo

combining form denoting hair. Example: pilosis (excessive development of).... pilo

Pilomatrixoma

n. a benign (noncancerous) skin tumour that typically occurs in the head and neck area, including the eyelids. The tumour usually does not cause any symptoms and is commonest in children.... pilomatrixoma

Pilomotor Nerves

sympathetic nerves that supply muscle fibres in the skin, around the roots of hairs. Activity of the sympathetic nervous system causes the muscles to contract, raising the hairs and giving the *gooseflesh effect of fear or cold.... pilomotor nerves

Pilonidal Sinus

a short tract leading from an opening in the skin in or near the cleft at the top of the buttocks and containing hairs. The sinus may be recurrently infected, leading to pain and the discharge of pus. Treatment is by surgical opening and cleaning of the sinus.... pilonidal sinus

Pilosebaceous

adj. relating to the hair follicles and their associated sebaceous glands.... pilosebaceous

Pilus

n. a hair. See also pili.... pilus

Pimecrolimus

n. see calcineurin inhibitors.... pimecrolimus

Pimel

(pimelo-) combining form denoting fat; fatty.... pimel

Pimozide

n. an *antipsychotic drug used to treat schizophrenia and some delusional disorders. It may cause serious disturbances of heart rhythm.... pimozide

Pimple

n. a small inflamed swelling on the skin that contains pus. It may be the result of bacterial infection of a skin pore that has become obstructed with fatty secretions from the sebaceous glands. Pimples occurring in large numbers on the chest, back, and face are usually described as *acne, a common condition of adolescence.... pimple

Pinard

n. an instrument used by midwives to auscultate the fetal heart. See intermittent auscultation.... pinard

Pincement

n. one of the techniques used in massage, in which pinches of the patient’s flesh are taken between finger and thumb and twisted or rolled before release. This is said to improve the tone of the skin, improve circulation, and alleviate underlying pain.... pincement

Pink Disease

a severe illness of children of the teething age, marked by pink cold clammy hands and feet, heavy sweating, raised blood pressure, rapid pulse, photophobia, loss of appetite, and insomnia. Affected infants are very prone to secondary infection, which may be fatal. It has been suggested that the condition is an allergic reaction to mercury, since it used to occur when teething powders, lotions, and ointments containing mercury were used. Although there is no definite proof of this, the disease has virtually disappeared since all mercury-containing paediatric preparations have been banned. Medical names: acrodynia, erythroedema, erythromelalgia.... pink disease

Pink Puffer

the typical appearance of a patient with chronic obstructive pulmonary disease, who is breathless and flushed. See also blue bloater.... pink puffer

Pinnaplasty

n. see otoplasty.... pinnaplasty

Pinocytosis

n. the intake of small droplets of fluid by a cell by cytoplasmic engulfment. It occurs in many white blood cells and in certain kidney and liver cells. Compare phagocytosis.... pinocytosis

Pipelle

n. a disposable flexible plastic endometrial sampling device consisting of an inner plunger and a 3-mm outer sheath, which is inserted through the cervix into the endometrial cavity to obtain a blind endometrial biopsy by gentle suction.... pipelle

Pirfenidone

n. a drug with antifibrotic and anti-inflammatory properties that is used to treat *idiopathic pulmonary fibrosis. It is thought to reduce fibroblast proliferation, inhibit *transforming growth factor-?-stimulated collagen production, and reduce the production of fibrogenic mediators. Pirfenidone has also been shown to reduce production of inflammatory mediators, such as *tumour necrosis factor and interleukin 1 (IL-1). Side effects include gastrointestinal upsets.... pirfenidone

Piriform Fossae

two pear-shaped depressions that lie on either side of the opening to the larynx.... piriform fossae

Pisiform Bone

the smallest bone of the wrist (*carpus): a pea-shaped bone that articulates with the triquetral bone and, indirectly by cartilage, with the ulna.... pisiform bone

Pithing

n. the laboratory procedure in which a part or the whole of the central nervous system of an experimental animal (such as a frog) is destroyed, usually by inserting a probe through the foramen magnum, in preparation for physiological or pharmacological experiments.... pithing

Pitting

n. the formation of depressed scars, as occurs on the skin following acne or (formerly) smallpox. Pitting oedema is swelling of the tissues due to excess fluid in which fingertip pressure leaves temporary indentations in the skin.... pitting

Pituicyte

n. a type of cell found in the posterior lobe of the pituitary gland, similar in appearance to an *astrocyte, with numerous fine branches that end in contact with the lining membrane of the blood channels in the gland.... pituicyte

Pituitary Apoplexy

acute intrapituitary haemorrhage, usually into an existing tumour, presenting as severe headache and collapse. It is a medical emergency. Due to the sudden expansion in size of the gland with the haemorrhage, it is accompanied by lesions of the cranial nerves running close to the pituitary gland, causing paralysis of the muscles of the orbit and occasionally the face. Anterior pituitary insufficiency usually results, but posterior pituitary function survives. Surprisingly, pituitary function usually recovers.... pituitary apoplexy

Pityrosporum

n. see Malassezia.... pityrosporum

Pivmecillinam

n. a *penicillin-type antibiotic used mainly to treat urinary-tract infections caused by many Gram-negative bacteria. Possible side-effects include allergic reactions, nausea, and vomiting.... pivmecillinam

Pivot Joint

see trochoid joint.... pivot joint

Pixel

n. short for ‘picture element’, the smallest individual component of an electronically produced image. Numerical values are ascribed to each pixel, which describe its position and relative intensity and/or colour. A two-dimensional *matrix of pixels produces the final image.... pixel

Pizotifen

n. an antihistamine drug used to prevent severe migraine and cluster headaches. It acts by inhibiting the effects of *serotonin. Possible side-effects include dizziness, drowsiness, and weight gain.... pizotifen

Placenta Accreta

a condition in which the placenta is abnormally strongly attached to the wall of the uterus with superficial penetration of chorionic *villi into the underlying *myometrium. Women with *placenta praevia and at least one previous Caesarean delivery are considered to be at high risk for placenta accreta. When placenta accreta is thought to be likely, consultant obstetric and anaesthetic input are vital in planning and conducting the delivery. Radiological input with temporary uterine balloon tamponade may be considered, and methotrexate has been used. The risk of haemorrhage, blood transfusion, and hysterectomy should be discussed. In placenta increta the chorionic villi extend into the myometrium; a placenta percreta occurs where the chorionic villi penetrate through the myometrial wall and can invade the bladder. An emergency hysterectomy is usually necessary in these rare cases.... placenta accreta

Placode

n. any of the thickened areas of ectoderm in the embryo that will develop into nerve ganglia or the special sensory structures of the eye, ear, or nose.... placode

Plagiocephaly

n. any distortion or lack of symmetry in the shape of the head, usually due to irregularity in the closure of the sutures between the bones of the skull.... plagiocephaly

Plane

n. a level or smooth surface, especially any of the imaginary flat surfaces – orientated in various directions – used to divide the body; for example, the *coronal and *sagittal planes.... plane

Planoconcave

adj. describing a structure, such as a lens, that is flat on one side and concave on the other.... planoconcave

Planoconvex

adj. describing a structure, such as a lens, that is flat on one side and convex on the other.... planoconvex

Plantar Arch

the arch in the sole of the foot formed by anastomosing branches of the plantar arteries.... plantar arch

Plantar Reflex

a reflex obtained by drawing a bluntly pointed object (such as a key) along the outer border of the sole of the foot from the heel to the little toe. The normal flexor response is a bunching and downward movement of the toes. An upward movement of the big toe is called an extensor response (or Babinski reflex or response). In all persons over the age of 18 months this is a sensitive indication of damage to the *pyramidal system in either the brain or spinal cord.... plantar reflex

Plantigrade

adj. walking on the entire sole of the foot: a habit of humans, bears, and some other animals.... plantigrade

Plasia

combining form denoting formation; development. Example: hyperplasia (excessive tissue formation).... plasia

Plasm

(plasmo-) combining form denoting 1. blood plasma. 2. protoplasm or cytoplasm.... plasm

Plasma Coagulation

a type of *electrocoagulation used to arrest haemorrhage or destroy abnormal tissue. A stream of inert gas, such as argon or helium, is ionized, thereby carrying electrical energy to adjacent tissue; there is no physical contact between the plasma coagulation apparatus and the tissue.... plasma coagulation

Plasmacytoma

n. a malignant tumour of plasma cells, often known as a ‘solitary myeloma’. Although usually occurring as a single tumour in bone marrow or more rarely soft tissue (extramedullary plasmacytoma), it may be multiple, in which case it is classified as a multiple myeloma. All of these tumours may produce the abnormal gammaglobulins that are characteristic of myeloma, and they may progress to widespread myeloma. The soft-tissue tumours often respond to radiotherapy and to such drugs as thalidomide and cyclophosphamide; the bone tumours are typically less responsive.... plasmacytoma

Plasmalogen

n. a phospholipid, found in brain and muscle, similar in structure to *lecithin and *cephalin.... plasmalogen

Plasminogen Activators

enzymes that convert the inactive substance *plasminogen to the active enzyme *plasmin, which digests blood clots (see fibrinolysis). There are two types of plasminogen activators, *tissue-type plasminogen activator (tPA) and urokinase-like plasminogen activator (uPA). See blood coagulation.... plasminogen activators

Plasmoditrophoblast

n. see trophoblast.... plasmoditrophoblast

Plasmolysis

n. a process occurring in bacteria and plants in which the protoplasm shrinks away from the rigid cell wall when the cell is placed in a *hypertonic solution. Plasmolysis is due to withdrawal of water from the cell by *osmosis.... plasmolysis

Plaster

n. adhesive tape used in shaped pieces or as a bandage to keep a dressing in place.... plaster

Plaster Model

(in dentistry) an accurate positive cast of the teeth and jaws made from modified plaster of Paris. A pair of models are used to study the dentition, particularly before treatment. Models are also used to construct dentures, orthodontic appliances, and such restorations as crowns.... plaster model

Plastibell Device

a plastic device that facilitates *circumcision while protecting the glans penis. It is widely used for circumcisions in newborn boys.... plastibell device

Plastic Lymph

a transparent yellowish liquid produced in a wound or other site of inflammation, in which connective tissue cells and blood vessels develop during healing.... plastic lymph

Plastron

n. the breastbone (*sternum) together with the costal cartilages attached to it.... plastron

Plasty

combining form denoting plastic surgery. Example: labioplasty (of the lips).... plasty

Platelet Activation

the process whereby platelets adhere to collagen released from endothelial cells in damaged blood vessels and aggregate to form a plug. An important metabolic pathway in platelets converts membrane phospholipids to *thromboxane A2 (TXA2), which can activate platelets. ADP, released from platelet granules, and *thrombin are other activators. The adhesive and aggregation reactions of platelets are mediated through surface membrane glycoproteins (Glp), Glp Ib and Glp IIb/IIIa. Aspirin acts as an *antiplatelet drug by irreversibly inhibiting one of the enzymes of this pathway, cyclo-oxygenase. Clopidrogel inhibits the ADP receptor on platelet membranes, and *abciximab blocks platelet aggregation by inhibiting Glp IIb/IIIa (see illustration overleaf).... platelet activation

Platelet-derived Growth Factor

(PDGF) see growth factor.... platelet-derived growth factor

Platy

combining form denoting broad or flat.... platy

Platysma

n. a broad thin sheet of muscle that extends from below the collar bone to the angle of the jaw. It depresses the jaw.... platysma

Pledget

n. a small wad of dressing material, such as lint, used either to cover a wound or sore or as a plug. It is also used during operations, mounted on an instrument, to wipe away blood or other fluids.... pledget

Plegia

combining form denoting paralysis. Example: hemiplegia (of one side of the body).... plegia

Pleio

(pleo-) combining form denoting 1. multiple. 2. excessive.... pleio

Pleiotropy

n. a situation in which a single gene is responsible for more than one effect in the *phenotype. The mutation of such a gene will therefore have multiple effects. —pleiotropic adj.... pleiotropy

Pleocytosis

n. the presence of an abnormally large number of lymphocytes in the cerebrospinal fluid, which bathes the brain and spinal cord.... pleocytosis

Pleomastia

(polymastia) n. multiple breasts or nipples. These are usually symmetrically arranged along a line between the mid point of the collar bone and the pelvis (the nipple line).... pleomastia

Pleomorphism

n. 1. the condition in which an individual assumes a number of different forms during its life cycle. The malarial parasite (Plasmodium) displays pleomorphism. 2. a feature of malignant neoplastic cells, which show a marked variation in the shapes of individual cells and cell nuclei.... pleomorphism

Pleoptics

n. special techniques practised by orthoptists (see orthoptics) for developing normal function of the macula (the most sensitive part of the retina), in people whose macular function has previously been disturbed because of strabismus (squint).... pleoptics

Plessimeter

(pleximeter) n. a small plate of bone, ivory, or other material pressed against the surface of the body and struck with a *plessor in the technique of *percussion.... plessimeter

Plessor

(plexor) n. a small hammer used to investigate nervous reflexes and in the technique of *percussion.... plessor

Pleur

(pleuro-) combining form denoting 1. the pleura. 2. the side of the body.... pleur

Pleurectomy

n. surgical removal of part of the *pleura, which is sometimes done to prevent further recurrences of spontaneous *pneumothorax or to remove diseased areas of pleura.... pleurectomy

Pleurocele

n. herniation of the pleura. See hernia.... pleurocele

Pleurocentesis

(thoracentesis, thoracocentesis) n. the insertion of a hollow needle into the *pleural cavity through the chest wall in order to withdraw fluid, blood, pus, or air.... pleurocentesis

Pleurodesis

n. the artificial production of pleurisy by chemical or mechanical means to obliterate the *pleural cavity, in order to prevent recurrent, usually malignant, pleural effusions.... pleurodesis

Pleurolysis

(pneumolysis) n. surgical stripping of the parietal *pleura from the chest wall to allow the lung to collapse. The procedure was used to help tuberculosis to heal, before the advent of effective antituberculous drugs.... pleurolysis

Pleuropneumonia

n. inflammation involving both the lung and pleura. See pleurisy; pneumonia.... pleuropneumonia

Pleurotyphoid

n. *typhoid fever involving the lungs.... pleurotyphoid

Pleximeter

n. see plessimeter.... pleximeter

Plexor

n. see plessor.... plexor

Plica

n. a fold of tissue; for example, the plica sublingualis, the mucous fold in the floor of the mouth. —plicate adj.... plica

Ploidy

n. the condition of having multiple the normal number of chromosomes for the species. An increase in ploidy in the cells of a malignant tumour usually indicates greater aggressiveness and ability to invade.... ploidy

Plombage

n. 1. a technique used in surgery for the correction of retinal detachment. A small piece of silicone plastic is sewn on the outside of the eyeball to produce an indentation over the retinal hole or tear to allow the retina to reattach. 2. the insertion of plastic balls into the pleural cavity to cause collapse of the lung. This was done in the days before effective antituberculous drugs to help tuberculosis to heal.... plombage

Plugged Biopsy

an *interventional radiology technique in which, after taking a sample of tissue (biopsy) to check for cancer cells or abnormality, the tract of the biopsy needle is plugged with materials to prevent bleeding at the site. It is mostly used for liver and renal biopsies.... plugged biopsy

Plummer’s Disease

a hyperfunctioning, usually benign, *adenoma of the thyroid gland, which can be palpated and appears as a ‘hot nodule’ on radioactive thyroid scanning. Treatment is to control the nodule with antithyroid drugs and then remove it surgically or destroy it permanently with radioactive iodine. [H. S. Plummer (1874–1937), US physician]... plummer’s disease

Pluri

combining form denoting more than one; several.... pluri

Pluripotent

adj. see stem cell.... pluripotent

Pneo

combining form denoting breathing; respiration.... pneo

Pneum

combining form. see pneumo-.... pneum

Pneumat

(pneumato-) combining form denoting 1. the presence of air or gas. 2. respiration.... pneumat

Pneumatization

n. the presence of air-filled cavities in bone, such as the sinuses of the skull.... pneumatization

Pneumatocele

n. herniation of lung tissue. See hernia.... pneumatocele

Pneumatosis

n. the occurrence of gas cysts in abnormal sites in the body. Pneumatosis cystoides intestinalis is the occurrence of multiple gas-containing cysts in the intestinal wall. Its cause is unknown; it can be treated by *hyperbaric oxygenation.... pneumatosis

Pneumocephalus

(pneumocele) n. the presence of air within the skull, usually resulting from a fracture passing through one of the air sinuses. There may be a leak of cerebrospinal fluid at the site of the fracture, manifested as a watery discharge from the nose. Pneumocephalus can be detected by plain X-rays of the skull, which show air and a fluid level inside a cavity, or by CT and MRI scanning.... pneumocephalus

Pneumococcal Vaccine

a vaccine that protects against infection by the bacterium *Streptococcus pneumoniae, which can cause serious diseases, including pneumonia, septicaemia, and *meningitis. Children under 2 years of age and adults over 65 years are at particular risk. Since September 2006, the pneumococcal vaccine has become part of the childhood *immunization programme. It is also offered to people over the age of 65 as a single vaccination that will protect for life.... pneumococcal vaccine

Pneumocystis

n. a genus of protozoans. The species P. jiroveci (formerly carinii) causes pneumonia in immunosuppressed patients, usually following intensive chemotherapy. Pneumocystis jiroveci (carinii) pneumonia (PCP) is fatal in 10–30% of cases if untreated, but it can be overcome with high doses of *co-trimoxazole or *pentamidine.... pneumocystis

Pneumocyte

n. a type of cell that lines the walls separating the air sacs (see alveolus) in the lungs. Type I pneumocytes are flat and inconspicuous. Type II pneumocytes are cuboidal and secrete *surfactant.... pneumocyte

Pneumoencephalography

n. a technique used in the X-ray diagnosis of disease within the skull. Air is introduced into the cavities (ventricles) of the brain to displace the cerebrospinal fluid, thus acting as a *contrast medium. X-ray photographs show the size and disposition of the ventricles and the subarachnoid spaces. The technique has largely been superseded by CT and MRI scanning.... pneumoencephalography

Pneumograph

n. an instrument used to record the movements made during respiration.... pneumograph

Pneumolysis

n. see pleurolysis.... pneumolysis

Pneumomediastinum

n. air in the mediastinum visible on chest X-ray. It can be a complication of surgical *emphysema due to pneumothorax, but the air can originate from the upper airways or the upper gastrointestinal tract. A rare cause is gas-forming organisms. See Hamman’s sign.... pneumomediastinum

Pneumon

(pneumono-) combining form denoting the lung(s). Example: pneumonopexy (surgical fixation to the chest wall).... pneumon

Pneumopericardium

n. the presence of air within the membranous sac surrounding the heart. See hydropneumopericardium.... pneumopericardium

Pneumoretinopexy

n. a surgical technique in which an inert gas bubble is injected into the eye to press and seal breaks in the retina. When the retina is flat, a laser beam or *cryoretinopexy is applied to cause scarring and permanently seal the tear.... pneumoretinopexy

Pneumotonometer

(noncontact tonometer) n. an instrument that blows a puff of air at the cornea to cause flattening and hence measure intraocular pressure. It is commonly used by optometrists in tests for glaucoma.... pneumotonometer

Pnoea

combining form denoting a condition of breathing. Example: dyspnoea (breathlessness).... pnoea

Pock

n. a small pus-filled eruption on the skin characteristic of *chickenpox and *smallpox rashes. See also pustule.... pock

Pocket

n. (in dentistry) see periodontal pocket.... pocket

Pocket Resuscitation Mask

a compressible and easily carried mask, which can be expanded and fitted over the mouth and nose of a nonbreathing patient in order to perform mouth-to-mouth resuscitation through a small valve without contact between the mouth of the rescuer and that of the patient.... pocket resuscitation mask

Podalic Version

(internal podalic version) a procedure in which the position of a fetus in the uterus is altered so that its feet will emerge first at birth. It is used mainly to deliver a second twin that is presenting transversely or obliquely. See also cephalic version.... podalic version

Podocyte

n. an epithelial cell in the *glomerulus that spreads over the capillary basement membrane and has branching tentacle-like processes that interdigitate with adjacent cells. The podocytes leave gaps or thin filtration slits. The slits are covered by slit diaphragms, which are composed of a number of cell-surface proteins including *nephrin, podocalyxin, and P-cadherin, which ensure that large molecules, such as albumin and gammaglobulin, are not filtered. Podocytes are damaged in *minimal change nephropathy and a major target of injury in *HIVAN.... podocyte

Podopompholyx

n. see pompholyx.... podopompholyx

Poems Syndrome

a syndrome, mostly reported in Japanese males, consisting of polyneuropathy (see peripheral neuropathy), organomegaly, endocrine failure, M protein (immunoglobulins) in the plasma, and skin changes, such as thickening, hirsutism, or excess sweating. Each of the components occurs with varying consistency. The cause is not known but it is not thought to be autoimmune in nature.... poems syndrome

Poiesis

combining form denoting formation; production. Example: haemopoiesis (of blood cells).... poiesis

Poikilo

combining form denoting variation; irregularity.... poikilo

Poikilocyte

n. an abnormally shaped red blood cell (*erythrocyte). Poikilocytes may be classified into a variety of types on the basis of their shape; for example elliptocytes (ellipsoid) and schistocytes (semilunar). See also poikilocytosis.... poikilocyte

Poikiloderma

n. a combination of pale and darkened skin with telangiectasia (see telangiectasis) and atrophy (wrinkled thin skin). This may be a sign of *cutaneous T-cell lymphoma.... poikiloderma

Poikilothermic

adj. cold-blooded: being unable to regulate the body temperature, which fluctuates according to that of the surroundings. Reptiles and amphibians are cold-blooded. Compare homoiothermic. —poikilothermy n.... poikilothermic

Pointillage

n. a procedure in massage in which the therapist’s fingers are pressed, fingertip first, deep into the patient’s skin. This is done to manipulate underlying structures and break up adhesions that may have formed following injury.... pointillage

Polar Body

one of the small cells produced during the formation of an ovum from an *oocyte that does not develop into a functional egg cell.... polar body

Pole

n. (in anatomy) the extremity of the axis of the body, an organ, or a cell.... pole

Poli

(polio-) combining form denoting the grey matter of the nervous system.... poli

Policeman’s Heel

see plantar fasciitis.... policeman’s heel

Polioencephalitis

n. a virus infection of the brain causing particular damage to the *grey matter of the cerebral hemispheres and the brainstem. The term is now usually restricted to infections of the brain by the poliomyelitis virus.... polioencephalitis

Polioencephalomyelitis

n. any virus infection of the central nervous system affecting the grey matter of the brain and spinal cord. *Rabies is the outstanding example.... polioencephalomyelitis

Poliovirus

n. one of a small group of RNA-containing viruses causing *poliomyelitis. They are included within the *picornavirus group.... poliovirus

Pollinosis

n. a more precise term than *hay fever for an allergy due to the pollen of grasses, trees, or shrubs.... pollinosis

Polyclinic

n. see health centre.... polyclinic

Polycoria

n. a rare congenital abnormality of the eye in which there are one or more holes in the iris in addition to the pupil.... polycoria

Polycystin

n. see polycystic disease of the kidneys.... polycystin

Polycystic Disease Of The Kidneys

either of two inherited disorders in which renal cysts are a common feature. Autosomal recessive polycystic kidney disease (ARPKD) occurs in about 1 in 20,000 live births. It is due to a single mutation on chromosome 6 for the gene encoding the protein fibrocystin. The majority of cases are diagnosed before or at birth. The most severely affected fetuses have enlarged kidneys and *oligohydramnios due to poor fetal renal output. These fetuses develop the ‘Potter’ phenotype with characteristic facies, pulmonary hypoplasia, and deformities of the spine and limbs. Those surviving the neonatal period (50–70%) develop varying degrees of renal impairment but this may not proceed to end-stage until early adulthood.

Autosomal dominant polycystic kidney disease (ADPKD) affects between 1 in 400 and 1 in 1000 individuals and is one of the most common hereditary diseases. Two types have been defined. ADPKD 1 is the commonest and responsible for about 85% of cases. It is due to a mutation in the PKD1 gene on chromosome 16, which encodes polycystin 1, an *ion-channel-regulating protein. ADPKD2 is due to a mutation in the PKD2 gene on chromosome 4, which encodes the protein polycystin 2, a calcium-release channel. ADPKD2 tends to be a milder disease with later presentation.

ADPKD is a multisystem disorder that is also associated with cyst formation in other organs (particularly the liver), cardiovascular disorders, and colonic diverticular disease. Renal disease presents in early adult life with haematuria, loin pain, urinary tract infection, hypertension, renal stone disease, or the finding of a mass in the abdomen. Other cases are identified by family contact tracing; the findings of a few cysts on renal ultrasonography in a young adult with a family history of ADPKD is highly suggestive of the disease. Renal disease is progressive and about 50% of patients will have reached end-stage by the time they enter their seventh decade. The progress of the renal failure can be slowed by good blood pressure control. In the UK, patients with ADPKD are responsible for 5–10% of the total on renal replacement therapy.

There are a number of separate rare autosomal dominant conditions other than ADPKD1 and ADPKD 2 that can present with polycystic kidneys. These include *von Hippel-Lindau disease and *tuberous sclerosis.... polycystic disease of the kidneys

Polycythaemia Vera

(polycythaemia rubra vera, Vaquez–Osler disease) a disease in which the number of red cells in the blood is greatly increased (see also polycythaemia). There is often also an increase in the numbers of white blood cells and platelets. Symptoms include headache, thromboses, *cyanosis, *plethora, and itching. Polycythaemia vera may be treated by blood-letting, but more severe cases may need to be treated with cytotoxic drugs. The cause of the disease is not known.... polycythaemia vera

Polydactylism

n. see hyperdactylism.... polydactylism

Polymastia

n. see pleomastia.... polymastia

Polymer

n. a substance formed by the linkage of a large number of smaller molecules known as monomers. An example of a monomer is glucose, whose molecules link together to form glycogen, a polymer. Polymers may have molecular weights from a few thousands to many millions. Polymers made up of a single type of monomer are known as homopolymers; those of two or more monomers as heteropolymers.... polymer

Polymorphic Eruption Of Pregnancy

(PEP) intensely itchy papules and weals on the abdomen (except the umbilicus), upper limbs, and buttocks, usually within the *striae gravidarum; it is also known as PUPPP (pruritic urticarial papules and plaques of pregnancy). It occurs in 1 in 250 first pregnancies late in the third trimester. This condition is harmless to mother and baby, but can be very annoying. It lasts an average of 6 weeks and resolves spontaneously 1–2 weeks after delivery. The most severe itching normally lasts for no more than a week.... polymorphic eruption of pregnancy

Polymorphous Light Eruption

see photodermatosis.... polymorphous light eruption

Polymyxin B

an *antibiotic used to treat severe infections caused by Gram-negative bacteria. Formulated with other drugs, it is administered for ear, eye, and skin infections.... polymyxin b

Polyneuropathy

n. see peripheral neuropathy.... polyneuropathy

Polynucleotide

n. a long chain of linked *nucleotides, of which molecules of DNA and RNA are made.... polynucleotide

Polyopia

n. the sensation of multiple images of one object. It is sometimes experienced by people with early cataract. See also diplopia.... polyopia

Polyorchidism

n. a congenital abnormality resulting in more than two testes.... polyorchidism

Polyphagia

n. excessive eating.... polyphagia

Polyphyletic

adj. describing a number of individuals, species, etc., that have evolved from more than one ancestral group. Compare monophyletic.... polyphyletic

Polyploid

adj. describing cells, tissues, or individuals in which there are three or more complete sets of chromosomes. Compare diploid; haploid. —polyploidy n.... polyploid

Polypectomy

n. the endoscopic or surgical removal of a *polyp. The technique used depends upon the site and size of the polyp. Endoscopically, polyps can be removed by various methods. A hot biopsy involves coagulation of a small polyp using a diathermy current passed through biopsy forceps, which obtains a sample for analysis at the same time. Cold biopsy involves removal of a polyp using forceps alone, thereby decreasing the perforation risk. Snare polypectomy uses a wire loop (snare) to cut through the base of the polyp. This is performed with or without a diathermy current (hot snare vs. cold snare); the current reduces the risk of bleeding by coagulating local blood vessels as the snare cuts through the polyp. Endoscopic mucosal resection (EMR) involves lifting a flat polyp by injecting a hypertonic solution into the submucosa beneath the polyp followed by snare polypectomy with diathermy. Nasal polyps may be removed using *endoscopic sinus surgery techniques, sometimes utilizing a *microdebrider.... polypectomy

Polypoid

adj. having the appearance of a *polyp.... polypoid

Polyradiculitis

(polyradiculopathy) n. any disorder of the peripheral nerves (see neuropathy) in which the brunt of the disease falls on the nerve roots where they emerge from the spinal cord. An abnormal allergic response in the nerve fibres is thought to be one cause of this condition; the *Guillain-Barré syndrome is an example. Other causes include infections (such as syphilis), herpesviruses, and tumours (such as lymphoma or other forms of cancer).... polyradiculitis

Polyribosome

n. see polysome.... polyribosome

Polyserositis

n. inflammation of the membranes that line the chest, abdomen, and joints, with accumulation of fluid in the cavities. Commonly the condition is inherited and intermittent and is termed familial Mediterranean fever. If complicated by infiltration of major organs by a glycoprotein (see amyloidosis) the disease usually proves fatal. Regular administration of colchicine will prevent the attacks in 95% of patients.... polyserositis

Polysome

(polyribosome) n. a structure that occurs in the cytoplasm of cells and consists of a group of *ribosomes linked together by *messenger RNA molecules: formed during protein synthesis.... polysome

Polysomnograph

n. a record of measurements of various bodily parameters during sleep. It is used in the diagnosis of sleep disorders, such as *obstructive sleep apnoea.... polysomnograph

Polyspermia

n. 1. excessive formation of semen. 2. see polyspermy.... polyspermia

Polyspermy

(polyspermia) n. fertilization of a single ovum by more than one spermatozoon: the development is abnormal and the embryo dies.... polyspermy

Polythelia

n. a congenital excess of nipples (see pleomastia).... polythelia

Pomalidomide

n. a derivative of *thalidomide with similar properties. It is taken in the treatment of relapsed or refractory myeloma. The main side-effects include lethargy, low blood counts, and thromboembolism; this drug should not be used in women who are pregnant or capable of becoming pregnant.... pomalidomide

Pontic

n. (in dentistry) see bridge.... pontic

Popliteus

n. a flat triangular muscle at the back of the knee joint, between the femur and tibia, that helps to flex the knee. —popliteal adj.... popliteus

Porcelain

n. (in dentistry) a ceramic material that is used to construct tooth-coloured crowns, inlays, or veneers.... porcelain

Porencephaly

n. an abnormal communication between the lateral *ventricle and the surface of the brain. This is usually a consequence of brain injury or cerebrovascular disease; uncommonly it may be a developmental defect, when it would most likely affect both lateral ventricles.... porencephaly

Porfimer Sodium

see photodynamic therapy.... porfimer sodium

Porocephaliasis

n. a rare infestation of the nasal cavities, windpipe, lungs, liver, or spleen by the nymphs of the parasitic arthropod *Porocephalus. Humans become infected on consumption of water or uncooked vegetables contaminated with the parasite’s eggs. There may be some abdominal pain while the parasite is in the gut but in many cases there are no symptoms.... porocephaliasis

Porocephalus

n. a genus of wormlike arthropods occurring mainly in tropical Africa and India. The legless adults are parasites in the lungs of snakes. The eggs, which are ejected with the snake’s bronchial secretions, may be accidentally swallowed by humans. The larva bores through the gut wall and usually migrates to the liver, where it develops into a nymph (see porocephaliasis).... porocephalus

Porphin

n. a complex nitrogen-containing ring structure and parent compound of the *porphyrins.... porphin

Porphobilinogen

n. a pigment that appears in the urine of individuals with acute *porphyria, causing it to darken if left standing.... porphobilinogen

Porphyrin

n. one of a number of pigments derived from *porphin, which are widely distributed in living things. All porphyrins form chelates with iron, magnesium, zinc, nickel, copper, and cobalt. These chelates are constituents of *haemoglobin, *myoglobin, the *cytochromes, and chlorophyll, and are thus important in many oxidation/reduction reactions in all living organisms. See also protoporphyrin IX.... porphyrin

Porphyrinuria

n. the presence in the urine of breakdown products of the red blood pigment haemoglobin (porphyrins), sometimes causing discoloration. See porphyria; porphobilinogen.... porphyrinuria

Porta

n. the aperture in an organ through which its associated vessels pass. Such an opening occurs in the liver (porta hepatis).... porta

Portable

adj. (in radiography) referring to images obtained by the bedside of the patient using light-weight equipment, rather than in the radiography department. The quality of portable radiographs is usually limited due to compromises in the equipment design to keep it light and movable, which is necessary when patients cannot easily be moved (for example, on intensive therapy units).... portable

Portacaval Anastomosis

(portacaval shunt) 1. a surgical technique in which the hepatic portal vein is joined to the inferior vena cava. Blood draining from the abdominal viscera is thus diverted past the liver. It is no longer widely used in the treatment of *portal hypertension. 2. any of the natural communications between the branches of the hepatic portal vein in the liver and the inferior vena cava.... portacaval anastomosis

Portal

adj. 1. relating to the portal vein or system. 2. relating to a porta.... portal

Portal Image

an electronic image taken during radiotherapy treatment to verify the position of radiation beams.... portal image

Positive

adj. see normative.... positive

Positive-pressure Ventilation

see noninvasive ventilation.... positive-pressure ventilation

Positive Symptoms

(in psychiatry) symptoms of schizophrenia characterized by a distortion of some aspect of functioning, such as delusions, hallucinations, or disordered speech. Compare negative symptoms.... positive symptoms

Positron

n. an electrically charged particle released in some radioactive decays, notably fluorine-18 or nitrogen-13, that has the same mass as an electron but opposite charge. It has a very short lifetime as it quickly reacts with an electron (annihilation) to produce a pair of *gamma rays, which are emitted in diametrically opposite directions. The energy of each gamma ray is always 511 keV.... positron

Posology

n. the science of the dosage of medicines.... posology

Posset

n. a small amount of milk that is regurgitated, usually with some wind, by many babies after feeding.... posset

Possum

n. a device that enables severely paralysed patients to use typewriters, adding machines, telephones, and a wide variety of other machines. Modern Possums are operated by micro-switches that require only the slightest movement in any limb. The original device worked by blowing and sucking a mouthpiece. The name derives from Patient-Operated Selector Mechanism (POSM).... possum

Possum Scoring

physiological and operative severity score for the enumeration of morbidity and mortality: a tool used by anaesthetists in the perioperative period to determine the risks associated with surgery in an individual patient. This can be used to guide such decisions as the appropriateness of surgery and the requirement for intensive care postoperatively.... possum scoring

Postcentral

adj. 1. situated behind any centre. 2. situated behind the central fissure of the brain.... postcentral

Postcibal

adj. occurring after eating.... postcibal

Postcoital Bleeding

genital-tract bleeding occurring after sexual intercourse. This is an important symptom and may be caused by sexually transmitted infections, vaginal candidiasis, atrophic *vaginitis, cervical *ectropion, cervical polyp, or cervical cancer.... postcoital bleeding

Postcoital Test

a test used in the investigation of infertility. A specimen of cervical mucus, taken 6–24 hours after coitus, is examined under a microscope. The appearance of 10 or more progressively motile spermatozoa per high-power field in the specimen indicates that there is no abnormal reaction between spermatozoa and mucus. The test should be undertaken in the postovulatory phase of the menstrual cycle.... postcoital test

Posterior Capsular Opacification

progressive clouding of the posterior lens capsule due to *Elschnig pearls and proliferation of lens fibres following extracapsular *cataract extraction by *phacoemulsification. This can lead to clouding of vision and is treated with YAG laser *capsulotomy.... posterior capsular opacification

Postero

combining form denoting posterior. Example: posterolateral (behind and at the side of).... postero

Posteroanterior

(PA) adj. from the back to the front. In radiography it refers to the direction of the X-ray beam (i.e. from the back to the front of the patient); thus a PA radiograph is taken with the X-ray film in front of the patient. Normally, a chest radiograph will be PA: since the heart is in the front of the chest, its size can be most accurately assessed if the X-ray film is in front of the chest. Compare decubitus; anteroposterior.... posteroanterior

Postganglionic

adj. describing a neuron in a nerve pathway that starts at a ganglion and ends at the muscle or gland that it supplies. In the sympathetic nervous system, postganglionic fibres are *adrenergic, unlike those in the parasympathetic system, which are *cholinergic. Compare preganglionic.... postganglionic

Postgastrectomy Syndrome

see dumping syndrome.... postgastrectomy syndrome

Posthitis

n. inflammation of the foreskin. This usually occurs in association with inflammation of the glans penis (balanitis; see balanoposthitis). Pain, redness, and swelling of the foreskin occurs due to bacterial infection. Treatment is by antibiotic administration, and subsequent *circumcision prevents further attacks.... posthitis

Posthumous Birth

1. delivery of a child by *Caesarean section after the mother’s death. 2. birth of a child after the father’s death.... posthumous birth

Postictal Phase

the recovery phase that follows immediately after an epileptic seizure (see epilepsy). It may last anything from a few minutes to several hours and is typically characterized by drowsiness, confusion, loss of memory, and feelings of sadness or anxiety. See ictus.... postictal phase

Postmature

adj. describing a baby born after 42 weeks of gestation (calculated from the first day of the last menstrual period). Such a birth can be associated with maternal diabetes or with *anencephaly in the fetus. —postmaturity n.... postmature

Postmenopausal Bleeding

(PMB) bleeding from the female genital tract occurring more than 12 months after the last menstrual period. Atrophic *vaginitis is a common cause. Endometrial cancer occurs in up to 10% of cases, and PMB may also be a marker of ovarian, cervical, or more rarely vaginal or vulval cancer.... postmenopausal bleeding

Postmenopause

n. the period of a woman’s life after the *menopause, i.e. following 12 months after her last menstrual period. The term ‘menopause’ is often used in reference to the postmenopausal period.... postmenopause

Postmicturition Dribble

a *lower urinary tract symptom in which a dribble occurs after voiding has been completed, often after leaving the toilet. It is quite common in men but is not caused by benign prostatic hyperplasia.... postmicturition dribble

Post Mortem

Latin: after death. See autopsy.... post mortem

Postnasal Space

see nasopharynx.... postnasal space

Postoperative

adj. following surgery: referring to the condition of a patient or to the treatment given at this time.... postoperative

Postpartum Blues

see baby blues.... postpartum blues

Postpartum Sepsis

see sepsis.... postpartum sepsis

Post-polio Syndrome

insidious numbness in muscles that develops 15–20 years after an attack of *poliomyelitis; the muscles may or may not have been previously affected. It may be caused by loss of nerve cells that have been under greater strain than normal as a result of the polio; there is no evidence of reactivation of the poliovirus. The syndrome also includes other symptoms, such as fatigue and pain, which may be due to secondary mechanical causes.... post-polio syndrome

Postprandial

adj. occurring after eating.... postprandial

Post-processing

n. (in radiology) the electronic manipulation of digitally acquired images (see digitization) following an examination in order to improve diagnostic accuracy or to improve and optimize visualization.... post-processing

Postresuscitation Care

medical care given to an individual who has survived a *cardiac arrest. This will usually consist of a 12-lead electrocardiogram (see lead2), a chest X-ray, a number of venous and arterial blood tests, and transfer to a high-dependency or coronary care unit for further intensive monitoring and drug administration.... postresuscitation care

Post-term Pregnancy

a pregnancy that has gone beyond 42 weeks gestation or 294 days from the first date of the last menstrual period.... post-term pregnancy

Postural Muscles

(antigravity muscles) muscles (principally extensors) that serve to maintain the upright posture of the body against the force of gravity.... postural muscles

Posturing

n. (in psychiatry) voluntarily assuming and maintaining bizarre or inappropriate postures. It is a feature of *catatonia.... posturing

Postviral Fatigue Syndrome

see CFS/ME/PVF.... postviral fatigue syndrome

Potassium-channel Activator

any one of a class of drugs that enhance the movement of potassium ions through the *ion channels in cell membranes. In the case of smooth muscle cells, such as those in the walls of arteries, their sensitivity to the normal stimuli to contract is reduced. The result is relaxation of the muscle fibres and widening of the arteries. Potassium-channel activators are used for improving the blood supply to the heart muscle in angina pectoris. Possible side-effects include headache, flushing, vomiting, dizziness, and weakness. A currently available member of the class is nicorandil.... potassium-channel activator

Potassium Chloride

a salt of potassium used to prevent and treat potassium deficiency, especially during treatment with digoxin or anti-arrhythmic drugs. Some irritation in the digestive system may occur. Severe potassium deficiency may be treated by intravenous infusion.... potassium chloride

Potter Syndrome

a congenital condition characterized by absence of kidneys, resulting in decreased amniotic fluid (see oligohydramnios) and compression of the fetus. Babies have poorly developed lungs, a characteristic wrinkled and flattened facial appearance, and leg deformities and do not usually survive. [E. L. Potter (20th century), US pathologist]... potter syndrome

Pott’s Disease

*tuberculosis of the backbone. Untreated, it can lead to a hunchback deformity. Treatment is antituberculous chemotherapy and occasionally surgery. [P. Pott (1714–88), British surgeon]... pott’s disease

Pouch

n. 1. (in anatomy) a small sac-like structure, especially occurring as an outgrowth of a larger structure. The pouch of Douglas is a pouch of peritoneum occupying the space between the rectum and uterus. 2. (in surgery) a sac created from a loop of intestine and used to replace a section of rectum that has been surgically removed, for example in the treatment of ulcerative colitis (see ileal pouch), or to replace the bladder after *cystectomy.... pouch

Poupart’s Ligament

see inguinal ligament. [F. Poupart (1661–1708), French anatomist]... poupart’s ligament

Poverty Of Speech

brief hesitant speech using few words (often monosyllables) and lacking spontaneity. It can be observed in patients with schizophrenia, dementia, and depression.... poverty of speech

Poxvirus

n. one of a group of large DNA-containing viruses including those that cause *smallpox (variola) and *cowpox (vaccinia) in humans, and pox and tumours in animals.... poxvirus

Pprom

preterm prelabour (or premature) rupture of membranes: spontaneous rupture of fetal membranes prior to 37 weeks gestation in the absence of regular painful contractions. This can be monitored for any signs of infection (*chorioamnionitis). Compare PROM.... pprom

Practice Development

a policy of actively and continuously improving patient care, with an emphasis on interprofessional collaboration and the integration of evidence-based practice with *person-centred care.... practice development

Practice Manager

the person responsible for running a doctor’s surgery, whose role involves managing staff, accounts, and medical records as well as developing the practice’s business strategy. Practice managers also liaise with external bodies, such as local NHS trusts and social service departments, to ensure efficient communication between the various organizations.... practice manager

Practice Nurse

a trained nurse caring for the patients of one or more general practitioners in the consulting room and on domiciliary consultations. In Britain, practice nurses are usually employed directly by GPs. However, they may also be employed by clinical commissioning groups as practice nurses or *district nurses.... practice nurse

Practitioner Performance Advice

part of *NHS Resolution that provides advice and support to NHS trusts and health authorities in England, Wales, and Northern Ireland regarding concerns about the performance of individual doctors, dentists, and pharmacists. The emphasis of the service is on local resolution. It was formerly known as the National Clinical Assessment Service (NCAS).

Information from the NHS Resolution website... practitioner performance advice

Prader Orchidometer

see orchidometer.... prader orchidometer

Prader–willi Syndrome

(Prader–Willi–Labhart syndrome) a congenital condition that is inherited as an autosomal *dominant trait and is due to an abnormality of chromosome 15 (see imprinting). It is marked by pathological overeating and resulting obesity (affected children often subsequently develop type 2 diabetes), lethargy, short stature, a characteristic facial expression, learning disabilities, and underactivity of the testes or ovaries (*hypogonadism) due to lack of pituitary gonadotrophins. It is a cause of delayed puberty. [A. Prader, H. Willi, and A. Labhart (20th century), Swiss paediatricians]... prader–willi syndrome

Prasugrel

n. see antiplatelet drug.... prasugrel

Prebiotics

pl. n. nondigestible constituents of food, such as inulin and fructo-oligosaccharides, which stimulate the growth of ‘good’ bacteria in the colon (see probiotics).... prebiotics

Precipitinogen

n. any antigen that is precipitated from solution by a *precipitin.... precipitinogen

Precision Attachment

(in dentistry) a machined joint that aids the retention of certain types of removable partial *dentures. The attachment is in two parts, one fixed to the denture (usually the ‘female’ part) and the other fixed to a crown (usually the ‘male’ part) on one of the teeth abutting the denture.... precision attachment

Precordial Thump

a thump delivered directly to the chest wall over the heart as the first stage in treatment of a *cardiac arrest if the arrest has been witnessed (i.e. just happened) and monitored (i.e. diagnosis is immediately confirmed). The shock in that early stage can depolarize enough of the heart muscle to allow the normal *pacemaker systems within the heart to take over and restore normal cardiac output.... precordial thump

Precordium

n. the region of the thorax immediately over the heart. —precordial adj.... precordium

Precuneus

n. an area of the inner surface of the cerebral hemisphere on each side, above and in front of the *corpus callosum. See cerebrum.... precuneus

Prediabetes

n. see glucose tolerance test.... prediabetes

Predisposition

n. a tendency to be affected by a particular disease or kind of disease. Such a tendency may be hereditary or may arise because of such factors as lack of vitamins, food, or sleep. See also diathesis.... predisposition

Prefrontal Lobe

the region of the brain at the very front of each cerebral hemisphere (see frontal lobe). The functions of the lobe are concerned with emotions, memory, learning, and social behaviour. Nerve tracts in the lobe are cut during the operation of prefrontal *leucotomy.... prefrontal lobe

Pregabalin

n. see gabapentin.... pregabalin

Preganglionic

adj. describing fibres in a nerve pathway that end in a ganglion, where they form synapses with *postganglionic fibres that continue the pathway to the effector organ, muscle or gland.... preganglionic

Pregestational Diabetes

Pre-existing diabetes mellitus in a woman who becomes pregnant. Pregnancy has profound effects on diabetic control and insulin requirements, which are almost doubled, and hypoglycaemia is more common. There is an increased risk of many complications, including fetal *macrosomia and *shoulder dystocia, and pre-eclampsia is twice as common in diabetic pregnancies. *Polyhydramnios and preterm labour are also more common. Even in well-controlled cases, delivery is normally indicated approximately two weeks before the estimated date due to the size of the baby and falling insulin requirements with late gestation, which can affect the uteroplacental flow.... pregestational diabetes

Pregnancy Epulis

(pregnancy tumour, granuloma gravidarum) a benign growth on the gums caused by inflammation of the gingivae during pregnancy. This type of *epulis may not need any specific treatment as it often shrinks post-partum.... pregnancy epulis

Pregnancy-induced Hypertension

(PIH) raised blood pressure (>140/90 mmHg) developing in a woman during the second half of pregnancy. It usually resolves within six weeks of delivery and is associated with a better prognosis than *pre-eclampsia.... pregnancy-induced hypertension

Pregnancy Of Unknown Location

(PUL) a positive pregnancy test when no fetus can be seen on an ultrasound scan, which is due to a very early ongoing pregnancy, an early failing pregnancy, or an ectopic pregnancy not located on scan.... pregnancy of unknown location

Pregnanediol

n. a steroid that is formed during the metabolism of the female sex hormone *progesterone. It occurs in the urine during pregnancy and certain phases of the menstrual cycle.... pregnanediol

Pregnenolone

n. a steroid synthesized in the adrenal glands, ovaries, and testes. Pregnenolone is an important intermediate product in steroid hormone synthesis and can – depending on the pathways followed – be converted to corticosteroids (glucocorticoids or mineralocorticoids), androgens, or oestrogens.... pregnenolone

Pregnancy Test

any of several methods used to demonstrate whether or not a woman is pregnant. Most pregnancy tests are based on the detection of a hormone, *human chorionic gonadotrophin (hCG), in the urine. The sample of urine is mixed with serum containing antibodies to hCG and marker particles (sheep red cells or latex particles) coated with hCG. In the absence of pregnancy, the antibodies will cause *agglutination of the marker particles. If the urine is from a pregnant woman, the antibodies will be absorbed and no agglutination will occur. These tests may be positive for pregnancy as early as 30 days after the date of the last normal period and are 98% accurate. Newer tests using *monoclonal antibodies (beta hCG) are more easily interpreted. When carried out on serum rather than urine, these tests give even earlier positive results.... pregnancy test

Preictal Phase

see aura.... preictal phase

Preimplantation Genetic Diagnosis

(PGD) a diagnostic procedure carried out on embryos at the earliest stage of development, before implantation in the uterus. Access to these early embryos requires the *in vitro fertilization of egg cells: three days after fertilization one or two cells are aspirated from the six-cell embryo; alternatively, tissue is removed from an embryo at five or six days, when it has reached the *blastocyst stage. Isolated cells can then be genetically analysed, allowing the transfer of selected embryos to the mother. One of the major applications of PGD is for the detection (using the *FISH technique) of chromosomal abnormalities, especially *aneuploidies (e.g. Down’s syndrome); the procedure is used mainly in women who have had repeated miscarriages or have failed to achieve pregnancy after several IVF treatment cycles, which could be due to the presence of such abnormalities in the embryo. PGD can also be used to detect defective genes responsible for hereditary disorders (e.g. the commonest form of cystic fibrosis, Huntington’s disease) and genes associated with susceptibility to certain cancers. When a defect is detected, *genetic counselling is offered.... preimplantation genetic diagnosis

Premature Ovarian Failure

menopause occurring before the age of 40. It may be caused by autoimmunity, chemotherapy, radiotherapy, or genetic factors, for example a mutation in the FSH receptor gene causing excess secretion of gonadotrophins and small underdeveloped ovaries. Treatment is by hormone replacement, either with the contraceptive pill or HRT. *Oocyte donation should be discussed if the patient wishes for assisted conception.... premature ovarian failure

Premature Rupture Of Membranes

see PROM; PPROM; labour.... premature rupture of membranes

Premyelocyte

n. see promyelocyte.... premyelocyte

Prenatal Diagnosis

(antenatal diagnosis) diagnostic procedures carried out on pregnant women in order to detect the presence of genetic or other abnormalities in the developing fetus. Ultrasound scanning (see ultrasonography) remains the cornerstone of prenatal diagnosis. Other procedures include chromosome and enzyme analysis of fetal cells obtained by *amniocentesis or, at an earlier stage of pregnancy, by *chorionic villus sampling (CVS). Noninvasive prenatal diagnosis involves a blood test to analyse cell-free fetal DNA in maternal blood. It can be performed during the first trimester and is used for fetal rhesus (Rh) determination in Rh-negative mothers, fetal sex determination in pregnancies at risk of sex-linked disorders, and for some single-sex gene disorders (e.g. achondroplasia). Compare prenatal screening.... prenatal diagnosis

Prenatal Screening

*screening tests carried out to estimate the risk of chromosomal or other abnormalities being present in a developing fetus. They include blood tests to measure levels of *human chorionic gonadotrophin (hCG), *PAPP-A, *alpha-fetoprotein (AFP), inhibin (see activin), and *unconjugated oestriol (uE3) (see also triple test) and also ultrasound scanning for the presence of soft markers (see ultrasound marker; nuchal translucency scanning). If the results indicate a high risk of abnormalities being present, a diagnosis may be confirmed by more invasive procedures (see prenatal diagnosis).... prenatal screening

Preneoplastic

adj. preceding the formation of a benign or malignant tumour (neoplasm). Preneoplastic lesions have the potential to give rise to tumours at that site. For example, mammary ductal epithelial *hyperplasia can give rise to *ductal carcinoma in situ. Preneoplastic conditions may result in tumours at that site or elsewhere. For example, ulcerative colitis predisposes to the development of colorectal *adenocarcinoma and *cholangiocarcinoma.... preneoplastic

Preoperative

adj. before operation: referring to the condition of a patient or to treatment, such as sedation, given at this time.... preoperative

Preparedness

n. (in psychology) a quality of some stimuli that makes them much more likely to trigger a pathological fear. For example, animals or high places are much more likely to become the subject of a *phobia than are plants or clothes. One theory is that individuals are genetically predisposed to *conditioning of fear to objects that have been a biological threat during human evolution.... preparedness

Prepatellar Bursitis

see housemaid’s knee.... prepatellar bursitis

Prepubertal

adj. relating to or occurring in the period before puberty.... prepubertal

Preputial Glands

modified sebaceous glands on the inner surface of the *prepuce.... preputial glands

Preputioplasty

(prepuceplasty) n. an alternative to circumcision to correct a tight foreskin (prepuce). The procedure involves a short longitudinal incision into the narrowed end of the prepuce that allows easy retraction. The inner and outer layers of the prepuce are then sutured together transversely to widen the preputial opening.... preputioplasty

Prepyramidal

adj. 1. situated in the middle lobe of the cerebellum, in front of the *pyramid. 2. describing nerve fibres in tracts that descend from the cerebral cortex to the spinal cord, before the crossing over that occurs at the pyramid of the medulla oblongata.... prepyramidal

Presby

(presbyo-) combining form denoting old age.... presby

Prescribed Disease

one of a number of *occupational diseases for which benefits are payable. These diseases arise as a result of employment requiring close contact with a hazardous substance or circumstance. Prescribed diseases are categorized by cause: physical, biological, chemical, or other. Examples include poisoning by such chemicals as mercury or benzene, decompression sickness in divers, and infections such as *anthrax in those handling wool. Some diseases that occur widely in the population may be prescribed in relation to a specific occupation (e.g. deafness in those working with pneumatic drills or tuberculosis in mortuary attendants). See also COSHH.... prescribed disease

Presenility

n. premature ageing of the mind and body, so that a person shows the reduction in mental and physical abilities normally found only in old age. See also dementia; progeria. —presenile adj.... presenility

Present

vb. 1. (of a patient) to come forward for examination and treatment because of experiencing specific symptoms (presenting symptoms). 2. (in obstetrics) see presentation.... present

Pressure Index

(PI) the ratio of the pressure in the posterior tibial artery to that in the brachial artery, which reflects the degree of arterial obstruction in the artery of the lower limb.... pressure index

Pressure Point

a point at which an artery lies over a bone on which it may be compressed by finger pressure, to arrest haemorrhage beyond. For example, the femoral artery may be compressed against the pelvic bone in the groin.... pressure point

Pressure Sore

(bedsore, decubitus ulcer) an ulcerated area of skin caused by continuous pressure on part of the body: a hazard to be guarded against in all bedridden (especially unconscious) patients. Healing is hindered by the reduced blood supply to the area, and careful nursing is necessary to prevent local gangrene. The patient’s position should be changed frequently (pressure-relieving mattresses are extremely helpful), and the buttocks, heels, elbows, and other regions at risk kept dry and clean.... pressure sore

Presymptomatic

adj. describing or relating to a symptom that occurs before the typical symptoms of a disease. See also prodromal.... presymptomatic

Presystole

n. the period in the cardiac cycle just preceding systole.... presystole

Preventive Resin Restoration

a hybrid between a *fissure sealant and a conventional *filling that is used to treat early dental caries involving dentine.... preventive resin restoration

Prickle Cells

cells with cytoplasmic processes that form intercellular bridges. The germinative layer of the *epidermis is sometimes called the prickle cell layer.... prickle cells

Prilocaine

n. a local *anaesthetic used particularly in dentistry. High doses of the drug may cause methaemoglobinaemia and cyanosis. Prilocaine is also a constituent of *EMLA cream.... prilocaine

Prima Facie

a principle that, at first sight, must be conformed with unless it conflicts with an equally important principle. Because each of the *four principles in medical ethics is prima facie, no one of them has overriding priority.... prima facie

Prime

vb. (in chemotherapy) to administer small doses of a *cytotoxic drug prior to high-dose chemotherapy and/or radiotherapy. This causes proliferation of the primitive bone marrow cells and aids subsequent regeneration of the bone marrow.... prime

Prime Mover

see agonist.... prime mover

Primitive Streak

the region of the embryo that proliferates rapidly, producing mesoderm cells that spread outwards between the layers of ectoderm and endoderm.... primitive streak

Primordial

adj. (in embryology) describing cells or tissues that are formed in the early stages of embryonic development.... primordial

Preterm Birth

(premature birth) birth of a baby before 37 weeks (259 days) of gestation (calculated from the first day of the mother’s last menstrual period); a birth at less than 23 weeks is at present incompatible with life. Such factors as *pre-eclampsia, multiple pregnancies (e.g. twins), maternal infection, and *cervical incompetence may all result in preterm births, but in the majority of cases the cause is unknown. Conditions affecting preterm babies may include *respiratory distress syndrome, feeding difficulties, inability to maintain normal body temperature, *apnoea, infection, *necrotizing enterocolitis, and brain haemorrhages. Supportive treatment is provided in an incubator in a neonatal unit; many infants survive with no residual impairment but the shorter the gestation period, the more serious are the problems to be overcome.... preterm birth

Primum Non Nocere

Latin for ‘first do no harm’, a traditional medical aphorism, similar to the Greek for ‘abstain from doing harm’ in the Hippocratic Oath and also to the *prima facie principle of *nonmaleficence. It is a reminder to first consider whether a proposed medical intervention risks causing more harm than good. See also risk–benefit analysis.... primum non nocere

Proarrhythmia

n. the paradoxical triggering of new heart rhythm disturbances by a drug given with the intention of inhibiting an *arrhythmia.... proarrhythmia

Probability

n. see significance.... probability

Proband

n. see propositus.... proband

Probang

n. a long flexible rod with a small sponge, ball, or tuft at the end, used to remove obstructions from the larynx or oesophagus (gullet). A probang is also used to apply medication to these structures.... probang

Probing Depth

a measurement of the depth of a periodontal pocket (see periodontal disease).... probing depth

Procarcinogen

n. a chemical substance that does not itself cause cancer but which can be converted by enzymatic action to another substance that can cause cancer (the ultimate *carcinogen).... procarcinogen

Proct

(procto-) combining form denoting the anus and/or rectum.... proct

Proctatresia

n. see imperforate anus.... proctatresia

Proctectasia

n. enlargement or widening of the rectum, usually due to long-standing constipation (see dyschezia).... proctectasia

Proctectomy

n. surgical removal of the rectum. It is usually performed for cancer of the rectum and may require the placement of a stoma (see colostomy). If the anus is left, an *ileal pouch can be constructed to replace the rectum.... proctectomy

Proctocele

n. see rectocele.... proctocele

Proctocolectomy

n. a surgical operation in which the rectum and colon are removed. In panproctocolectomy the entire rectum and colon are removed, necessitating either a permanent opening of the ileum (see ileostomy) or the construction of an *ileal pouch. This is usually performed for *ulcerative colitis.... proctocolectomy

Proctocolitis

n. inflammation of the rectum and colon, usually due to *ulcerative colitis. See also proctitis.... proctocolitis

Proctodeum

n. the site of the embryonic anus, marked by a depression lined with ectoderm. The membrane separating it from the hindgut breaks down in the third month of gestation. Compare stomodeum.... proctodeum

Proctodynia

n. see proctalgia.... proctodynia

Proctogram

n. an X-ray of the rectum taken after contrast material has been infused into it using a catheter. A defecating proctogram is a series of X-ray or MR images captured during defecation to highlight any abnormalities.... proctogram

Proctology

n. the study of disorders of the rectum and anus.... proctology

Proctorrhaphy

n. a surgical operation to stitch tears or lacerations of the rectum or anus.... proctorrhaphy

Proctoscope

n. an illuminated instrument that allows inspection of the distal rectum and the anus for the presence of haemorrhoids, rectal polyps or masses, anal fissures, and inflammation. Minor procedures (such as banding of haemorrhoids) may be performed during proctoscopy.... proctoscope

Proctosigmoiditis

n. inflammation of the rectum and the sigmoid (lower) colon. See also proctocolitis.... proctosigmoiditis

Proctotomy

n. incision into the rectum or anus to correct *stricture (narrowing) of the canal or to open an *imperforate anus.... proctotomy

Prodromal

adj. relating to the period of time between the appearance of the first symptoms of an infectious disease and the development of a rash or fever. A prodromal rash is one preceding the full rash of an infectious disease.... prodromal

Prodrug

n. a drug that requires metabolism in the liver before becoming biologically active. Examples are *carbimazole, which is metabolized to the pharmacologically active compound methimazole; and *capecitabine, which is metabolized to *fluorouracil.... prodrug

Proenzyme

(zymogen) n. the inactive form in which certain enzymes (e.g. digestive enzymes) are originally produced and secreted. The existence of this inactive form prevents the enzyme from breaking down the cells in which it was made. Once the proenzyme has been secreted it is converted to the active form.... proenzyme

Proerythroblast

n. the earliest recognizable precursor of the red blood cell (erythrocyte). It is found in the bone marrow and has a large nucleus and a cytoplasm that stains deep blue with *Romanowsky stains. See also erythroblast; erythropoiesis.... proerythroblast

Professionalism

n. possession of a high level of intellectual and technical expertise with a commitment to public service and the ability to practise autonomously within the regulations of the discipline. It calls for a special set of *values, behaviours, and relationships including respect and care for oneself as well as patients and others, honesty, *integrity, reliability, *responsibility, communication, collaboration, *compassion, *empathy, altruism, and *advocacy – but also self-awareness and a knowledge of limits (see burnout). Major shortcomings might be reported to a professional body (such as the *General Medical Council for UK doctors).... professionalism

Profilometer

n. a measuring device to quantify the roughness of a surface, such as eroded enamel.... profilometer

Profunda

adj. describing blood vessels that are deeply embedded in the tissues they supply.... profunda

Profundaplasty

n. surgical enlargement of the junction of the femoral artery and its deep branch, a common operation to relieve narrowing by atherosclerosis at this point.... profundaplasty

Proglottis

n. (pl. proglottids or proglottides) one of the segments of a *tapeworm. Mature segments, situated at the posterior end of the worm, each consist mainly of a branched uterus packed with eggs.... proglottis

Progressive Lenses

see varifocal lenses.... progressive lenses

Progressive Supranuclear Palsy

(Steele–Richardson–Olszewski syndrome) a progressive neurological disorder resulting from degeneration of the motor neurons, basal ganglia, and brainstem. Starting in late middle age, it is characterized by a staring facial expression due to impaired ability to move the eyes up and down, progressing to difficulties in swallowing, speech, balance, and movement and general spasticity. The condition enters the differential diagnosis of *parkinsonism, with which it is often confused in its early stages.... progressive supranuclear palsy

Proinsulin

n. a substance produced in the pancreas from which the hormone *insulin is derived.... proinsulin

Projection

n. (in psychology) the attribution of one’s own qualities to other people. In psychoanalysis this is considered to be one of the *defence mechanisms; people who cannot tolerate their own feelings (e.g. anger) may cope by imagining that other people have those feelings (e.g. are angry).... projection

Projective Test

(in psychology) a way of measuring aspects of personality, in which the subject is asked to talk freely about ambiguous objects. His responses are then analysed. Examples are the *Rorschach test and the Thematic Apperception Test (in which the subject invents stories about a set of pictures).... projective test

Prokinetic Agent

(prokinetic) an agent (e.g. *domperidone) that stimulates intestinal peristalsis, thus increasing gastrointestinal motility.... prokinetic agent

Proline

n. an *amino acid found in many proteins.... proline

Prom

prelabour (or premature) rupture of membranes: spontaneous rupture of membranes prior to the onset of labour. The majority of women who demonstrate this phenomenon will go into active labour spontaneously within the following 48 hours. Compare PPROM.... prom

Promegakaryocyte

n. an immature cell, found in the bone marrow, that develops into a *megakaryocyte.... promegakaryocyte

Prominence

n. (in anatomy) a projection, such as a projection on a bone.... prominence

Promontory

n. (in anatomy) a projecting part of an organ or other structure.... promontory

Promoter

(in oncogenesis) n. a substance that, in conjunction with an *initiator, leads to the production of a cancer.... promoter

Prompting

n. a technique used in *behaviour modification to elicit a response not previously present. The subject is made to engage passively in the required behaviour by instructions or by being physically put through the movements. The behaviour can then be rewarded (see reinforcement). This is followed by fading, in which the prompting is gradually withdrawn and the reinforcement maintained.... prompting

Promyelocyte

(premyelocyte) n. the developmental stage of a *granulocyte (a type of white blood cell) between the *myeloblast and the *myelocyte. It has abundant cytoplasm that, with *Romanowsky stains, appears blue with reddish granules. Promyelocytes are normally found in the blood-forming tissue of the bone marrow but may appear in the blood in a variety of diseases. See also granulopoiesis.... promyelocyte

Pronator

n. any muscle that causes pronation of the forearm and hand; for example, the pronator teres, a two-headed muscle arising from the humerus and ulna, close to the elbow, and inserted into the radius.... pronator

Pronephros

n. the first kidney tissue that develops in the embryo. It is not functional and soon disappears. Compare mesonephros; metanephros.... pronephros

Pronucleus

n. (pl. pronuclei) the nucleus of either the ovum or spermatozoon after fertilization but before the fusion of nuclear material. The pronuclei are larger than the normal nucleus and have a diffuse appearance.... pronucleus

Properdin

n. a group of substances in blood plasma that, in combination with *complement and magnesium ions, is capable of destroying certain bacteria and viruses. The properdin complex occurs naturally, rather than as the result of previous exposure to microorganisms, and its activity is not directed against any particular species. Compare antibody.... properdin

Prophase

n. the first stage of *mitosis and of each division of *meiosis, in which the chromosomes become visible under the microscope. The first prophase of meiosis occurs in five stages (see leptotene; zygotene; pachytene; diplotene; diakinesis).... prophase

Propositus

(proband) n. the first individual who is studied in an investigation of several related patients with an inherited or familial disorder.... propositus

Proprioceptor

n. a specialized sensory nerve ending (see receptor) that monitors internal changes in the body brought about by movement and muscular activity. Proprioceptors located in muscles and tendons transmit information that is used to coordinate muscular activity (see stretch receptor; tendon organ). See also mechanoreceptor.... proprioceptor

Prorennin

n. see rennin.... prorennin

Proscar

n. see finasteride.... proscar

Prosect

vb. to dissect a cadaver (or part of one) for anatomical demonstration. —prosection n. —prosector n.... prosect

Prosencephalon

n. the forebrain.... prosencephalon

Prosop

(prosopo-) combining form denoting the face. Example: prosopodynia (pain in).... prosop

Prosopagnosia

n. inability to recognize faces, either in person or in photographs, due to damage in the right occipito-temporal area of the brain. Causes include stroke and brain tumours.... prosopagnosia

Prostatic Intraepithelial Neoplasia

(PIN) abnormal cells in the prostate that are not cancer, but may be associated with cancer within the prostate. Typically, PIN will be found in prostate biopsies taken because levels of *prostate specific antigen are elevated. Multifocal high-grade PIN (HGPIN) on a prostate biopsy may indicate that another set of prostate biopsies should be taken in the future.... prostatic intraepithelial neoplasia

Prostatorrhoea

n. an abnormal discharge of fluid from the prostate gland. This occurs in some patients with acute *prostatitis, who complain of a profuse discharge from the urethra. The discharge is usually thin and watery and is often sterile on culture. The discharge usually subsides when the underlying prostatitis is controlled.... prostatorrhoea

Prosthodontics

(prosthetic dentistry) n. the branch of dentistry concerned with the provision of *dentures, *bridges, and *implant-retained prostheses.... prosthodontics

Prostate Cancer

a malignant tumour (*carcinoma) of the prostate gland, a common form of cancer in elderly men. In most men it progresses slowly over many years and gives symptoms similar to those of benign enlargement of the prostate (see prostate gland). Before it was possible to test for *prostate specific antigen (PSA), the tumour had often invaded locally, spread to regional lymph nodes, and metastasized to bone before clinical presentation. By checking elevated levels of PSA or *PCA3, prostate cancer can be detected 5–10 years before the tumour would present symptomatically. If the disease is confined to the prostate, the patient may be offered active surveillance or radical *prostatectomy, radical radiotherapy, or *brachytherapy; *cryotherapy or *HIFU are available in specialized centres. In elderly patients, it may be enough to monitor the tumour growth. If the disease is outside the prostate, androgen deprivation therapy may be used; this may be achieved by *gonadorelin analogues, *anti-androgens, surgical castration, or oestrogen therapy.... prostate cancer

Prostate Specific Antigen

(PSA) a protease enzyme produced by the glandular epithelium of the prostate. Its effect is to liquefy the semen within the ejaculate. Overall PSA has a half-life of 2–3 days. Increased quantities are secreted when the gland becomes enlarged or inflamed, and levels of PSA in the blood are significantly elevated in cancer of the prostate. Although there is no clear ‘cut-off’ level for normality, over 4 ng/ml in the blood is associated with a 20% risk of prostate cancer, even in patients with normal-feeling prostates on rectal examination. Age-specific PSA reference ranges are often used. Newer PSA assays can measure free PSA and compare it to the total PSA in the blood. Low free:total PSA ratios indicate a greater risk of prostate cancer and improve the discrimination between cancer and benign disease in men with a PSA in the range 4–10 ng/ml. PSA levels tend to be much higher in advanced prostate cancer and the rate of fall on treatment (e.g. after radical prostatectomy or radiotherapy) is a good prognostic indicator of response.... prostate specific antigen

Protamine

n. one of a group of simple proteins that can be conjugated with nucleic acids to form nucleoproteins. Protamine sulphate is injected as an antidote to heparin overdosage in oral anticoagulant therapy.... protamine

Protanopia

n. a defect in colour vision in which affected individuals are insensitive to red light and confuse reds, yellows, and greens. Compare deuteranopia; tritanopia.... protanopia

Protease Inhibitor

any one of a class of drugs used in the treatment of HIV infection and *AIDS. Used in combination with other *antiretroviral drugs, they act by inhibiting the action of protease, an enzyme produced by HIV that cleaves two precursor proteins into smaller fragments. These fragments are required for viral growth, infectivity, and replication. Protease inhibitors include atazanavir, indinavir, lopinavir and ritonavir (which are used in combination), saquinavir, and tipranavir. Side-effects include nausea, vomiting, diarrhoea, and rashes; these drugs are also associated with hyperglycaemia and *lipodystrophy. See also boceprevir.... protease inhibitor

Proteasome

n. a multi-enzyme complex in cells that breaks down proteins into short peptides.... proteasome

Protein Kinase

an enzyme that catalyses the transfer of a phosphate group from ATP to a specific amino acid residue of an intracellular protein (usually serine, threonine, or tyrosine), thereby affecting the biological activity of the protein. Protein kinase inhibitors are drugs that block the action of protein kinases in tumour cells and are used in the treatment of cancer. They include *sorafenib, *sunitinib, and *temsirolimus. See also tyrosine kinase inhibitor.... protein kinase

Proteolytic Enzyme

a digestive enzyme that causes the breakdown of protein. See endopeptidase; exopeptidase.... proteolytic enzyme

Proteose

n. a product of the hydrolytic decomposition of protein.... proteose

Proteus

n. a genus of rodlike Gram-negative flagellate highly motile bacteria common in the intestines and in decaying organic material. All species can decompose urea. Some species may cause disease in humans: P. vulgaris can cause urinary tract infections.... proteus

Prothrombin Time

(PT) the time taken for blood clotting to occur in a sample of blood to which calcium and thromboplastin have been added. A prolonged PT (compared with a control sample) indicates a deficiency of *coagulation factors, which – with calcium and thromboplastin – are required for the conversion of prothrombin to thrombin to occur in the final stages of blood coagulation. Measurement of PT is used to control anticoagulant therapy (e.g. with warfarin). See INR.... prothrombin time

Proto

combining form denoting 1. first. 2. primitive; early. 3. a precursor.... proto

Protodiastole

n. the short period in the cardiac cycle between the end of systole and the closure of the *aortic valve marking the start of diastole.... protodiastole

Proton-pump Inhibitor

a drug that reduces gastric acid secretion by blocking the *proton pump. Proton-pump inhibitors include esomeprazole, lansoprazole, *omeprazole, pantoprazole, and rabeprazole sodium; they are used for treating gastro-oesophageal reflux disease, peptic ulcer, and acid hypersecretion associated with *gastrinoma.... proton-pump inhibitor

Proton Therapy

a type of radiotherapy that uses a beam of protons. These charged particles are produced by a *cyclotron and penetrate only a predictable distance into the body depending on the proton energy. This is the radiotherapy treatment of choice for many childhood cancers, particularly brain and spinal tumours, as it can avoid more normal tissue and reduce the risk of long-term complications (including secondary malignancy) compared with photon (X-ray) beams.... proton therapy

Protopathic

adj. describing the ability to perceive only strong stimuli of pain, heat, etc. Compare epicritic.... protopathic

Protoplast

n. a bacterial or plant cell without its cell wall.... protoplast

Protoporphyrin Ix

the most common type of *porphyrin found in nature. It is a constituent of haemoglobin, myoglobin, most of the cytochromes, and the commoner chlorophylls.... protoporphyrin ix

Protozoan

n. a microorganism of the group *protozoa.... protozoan

Protozoology

n. the study of *protozoa.... protozoology

Protruding Ears

(otapostasis) external ears that stick out from the head more than average owing to absence of the antihelical fold of the *pinna. This is a normal variant but can be surgically corrected if desired using an *otoplasty operation. It was previously known as bat ears.... protruding ears

Protrusion

n. (in dentistry) 1. forward movement of the lower jaw. 2. a *malocclusion in which some of the teeth are further forward than usual. Compare retrusion.... protrusion

Protuberance

n. (in anatomy) a rounded projecting part, e.g. the projecting part of the chin (mental protuberance).... protuberance

Provitamin

n. a substance that is not itself a vitamin but can be converted to a vitamin in the body. An example is ?-carotene, which can be converted into vitamin A.... provitamin

Proxy

see delusion by proxy.... proxy

Proxy Decision

(surrogate decision) a decision made with or on behalf of a person who lacks full legal capacity to *consent to or refuse medical treatment. See best interests; Gillick competence; parental responsibility; power of attorney; substituted judgment.... proxy decision

Prrt

see peptide receptor radionuclide therapy.... prrt

Prune Belly Syndrome

(Eagle–Barrett syndrome) a hereditary condition, occurring exclusively in males, characterized by a deficiency of abdominal muscles, complex malformation of the urinary tract, and bilateral undescended testes. The lungs may be underdeveloped. The name derives from the typically wrinkled appearance of the skin over the abdomen.... prune belly syndrome

Prussic Acid

see hydrocyanic acid.... prussic acid

Psammoma

n. a tumour containing gritty sandlike particles (psammoma bodies). It is typical of cancer of the ovary but may also be found in the meninges (the membranes surrounding the brain).... psammoma

Pseud

(pseudo-) combining form denoting superficial resemblance to; false.... pseud

Pseudoagglutination

n. the misleading appearance of clumping that occurs during an antiserum-antigen test as a result of incorrect temperature or acidity of the solutions used.... pseudoagglutination

Pseudoaneurysm

n. see aneurysm.... pseudoaneurysm

Pseudocholinesterase

n. an enzyme found in the blood and other tissues that – like *cholinesterase – breaks down acetylcholine, but much more slowly. Not being localized at nerve endings, it plays little part in the normal breakdown of acetylcholine in synapses and at neuromuscular junctions.... pseudocholinesterase

Pseudocoxalgia

n. see Legg–Calve?–Perthes disease.... pseudocoxalgia

Pseudocrisis

n. a false *crisis: a sudden but temporary change in a condition, such as a fall of temperature in a patient with fever.... pseudocrisis

Pseudocryptorchidism

n. apparent absence of the testes. This is quite common in young boys, who retract their testes into the groin due to involuntary or reflex contraction of the cremasteric muscle of the suspensory cord (also known as retractile testes). The condition is only important in that it needs to be distinguished from true failure of descent of the testes into the scrotum, which requires early surgical treatment (see cryptorchidism).... pseudocryptorchidism

Pseudoexfoliation Syndrome

the appearance of white dandruff-like deposits on structures in the anterior chamber of the eye, which are especially prominent around the pupil margin and on the anterior lens capsule. It is a sign of zonular weakness and indicates an increased risk of secondary glaucoma.... pseudoexfoliation syndrome

Pseudohallucination

n. a controversial term, commonly used in *mental state examinations, for an experience described by the patient as a *hallucination but judged by the psychiatrist as not perceived as such by the patient. It may sometimes be seen as an attempt by patients to pretend that they suffer from genuine hallucinations. The term is generally unhelpful because it implies a value judgment.... pseudohallucination

Pseudohypertrophy

n. increase in the size of an organ or structure caused by excessive growth of cells that have a packing or supporting role but do not contribute directly to its functioning. The result is usually a decline in the efficiency of the organ although it becomes larger. —pseudohypertrophic adj.... pseudohypertrophy

Pseudohypoparathyroidism

n. a syndrome of learning disability, restricted growth, and bony abnormalities due to a genetic defect that causes lack of response to the hormone secreted by the *parathyroid glands. Treatment with calcium and vitamin D can reverse most of the features. See also Albright’s hereditary osteodystrophy.... pseudohypoparathyroidism

Pseudomembrane

n. a false membrane, consisting of a layer of exudate on the surface of the skin or a mucous membrane. In diphtheria a pseudomembrane forms in the throat. In pseudomembranous colitis, a disease caused by *Clostridium difficile that usually follows antibiotic therapy, pseudomembranes develop in the colon, resulting in profuse diarrhoea.... pseudomembrane

Pseudomembranous Colitis

see Clostridium; pseudomembrane.... pseudomembranous colitis

Pseudomyxoma

n. a mucoid tumour of the peritoneum, often seen in association with *myxomas of the ovary. In pseudomyxoma peritonei there are recurrent deposits of mucin-producing cells in the abdomen, which can be difficult to clear by surgery and may prove fatal.... pseudomyxoma

Pseudoneuritis

n. a condition that resembles *retrobulbar neuritis but is not due to inflammation. The most usual cause is blockage of blood vessels in the optic nerve (ischaemic optic neuropathy).... pseudoneuritis

Pseudo-obstruction

(Ogilvie’s syndrome) n. functional impairment of intestinal peristalsis without evidence of an obstructing lesion (acute colonic pseudo-obstruction). It presents with vomiting, marked abdominal distension, and constipation. It commonly occurs in hospitalized patients with serious illness, probably caused by abnormalities in colonic autonomic regulation and often associated with trauma, sepsis, the postoperative state following abdominal, pelvic, or orthopaedic surgery, or cardiac dysfunction (heart failure, myocardial infarction). Management is usually conservative and involves treatment of the underlying condition, the ‘drip and suck’ approach (see ileus), decompression of the colon, and prokinetic agents (such as neostigmine). Surgery is required when the conservative approach fails or in cases of perforation.... pseudo-obstruction

Pseudophakia

n. the state of the eye after the natural lens has been replaced by a synthetic lens implanted inside the eye, approximately in the position previously occupied by the natural lens. This is the current form of surgery for *cataract. —pseudophakic adj.... pseudophakia

Pseudopodium

n. (pl. pseudopodia) a temporary and constantly changing extension of the body of an amoeba or an amoeboid cell (see phagocyte). Pseudopodia engulf bacteria and other particles as food and are responsible for the movements of the cell.... pseudopodium

Pseudopolyposis

n. a condition in which the bowel lining (mucosa) is covered by elevated or protuberant plaques (pseudopolyps) that are not true *polyps but abnormal growths of inflamed mucosa. It is usually found in patients with longstanding *ulcerative colitis during endoscopy or barium enema examination.... pseudopolyposis

Pseudoprolactinoma

n. a mass in the pituitary gland region that is associated with a raised blood prolactin level due to interference of the pituitary stalk (through which the chemical dopamine, the inhibitor of prolactin release, passes from the hypothalamus) rather than to increased prolactin production from a pituitary *prolactinoma.... pseudoprolactinoma

Pseudopseudohypoparathyroidism

n. a condition in which all the symptoms of *pseudohypoparathyroidism are present but the patient’s response to parathyroid hormone is normal. It is often found in families affected with pseudohypoparathyroidism.... pseudopseudohypoparathyroidism

Pseudo Seizure

see non-epileptic seizure.... pseudo seizure

Pseudotumour Cerebri

see idiopathic intracranial hypertension.... pseudotumour cerebri

Psilosis

n. see sprue.... psilosis

Psoas Sign

an indicator of acute *appendicitis. The appendix lies close to the *iliopsoas muscle: if it is inflamed, any movement that involves the right psoas muscle (such as extension of the right thigh) will be painful in the right lower quadrant.... psoas sign

Psoralen

n. see PUVA.... psoralen

Psoriasis Area Severity Index

(PASI) a semiobjective severity score for psoriasis, including measurement of surface area affected and the degree of erythema, induration, and scale. It is commonly used in clinical trials and to ration expensive treatments for psoriasis. Severe disease equates to scores over 10 and it is often interpreted with the *dermatology life quality index (DLQI) score.... psoriasis area severity index

Psoriatic Arthritis

arthritis associated with *psoriasis. It occurs in 5% of patients with psoriasis and may be painful and disabling. It often affects small joints, such as the terminal joints of the fingers and toes, the spine (*spondylitis), and sacroiliac joints (*sacroiliitis), or large joints, such as the knee.... psoriatic arthritis

Psych

(psycho-) combining form denoting 1. the mind; psyche. 2. psychology.... psych

Psychedelic

adj. describing drugs that induce an altered state of consciousness or perception. Psychedelic drugs, which include *lysergic acid diethylamide (LSD) and *cannabis, are *hallucinogens and are used legally only for medical or scientific purposes.... psychedelic

Psychiatric Intensive Care Unit

see PICU.... psychiatric intensive care unit

Psychiatrist

n. a medically qualified physician who specializes in the study and treatment of mental disorders. In the UK psychiatrists classically qualify by specialist training for at least six years after medical school and *Foundation Programme years.... psychiatrist

Psychic

adj. 1. of or relating to the *psyche. 2. relating to parapsychological phenomena. 3. describing a person who is allegedly endowed with extrasensory or psychokinetic powers.... psychic

Psychogenic Polydipsia

see polydipsia.... psychogenic polydipsia

Psychogenic Purpura

see Gardner–Diamond syndrome.... psychogenic purpura

Psychomotor

adj. relating to muscular and mental activity. The term is applied to disorders in which muscular activities are affected by cerebral disturbance.... psychomotor

Psychomotor Epilepsy

see epilepsy.... psychomotor epilepsy

Psychoneuroimmunology

n. the study of the effects of the mind on the functioning of the immune system, especially in relation to the influence of the mind on susceptibility to disease and the progression of a disease.... psychoneuroimmunology

Psychopath

n. a person who behaves in an antisocial way and shows little or no guilt for antisocial acts and little capacity for forming emotional relationships with others. Psychopaths tend to respond poorly to treatment and do not learn from punishment, but many mature as they age. See also antisocial personality disorder. —psychopathic adj. —psychopathy n.... psychopath

Psychophysiology

n. the branch of psychology that records physiological measurements, such as the electrical resistance of the skin, the heart rate, the size of the pupil, and the electroencephalogram, and relates them to psychological events. —psychophysiological adj.... psychophysiology

Psychosexual Development

the process by which an individual becomes more mature in his or her sexual feelings and behaviour. Gender identity, sex-role behaviour, and choice of sexual partner are the three major areas of development. In Freudian psychoanalysis the phrase is sometimes used specifically for a sequence of stages, supposed by psychoanalytic psychologists to be universal, in which oral, anal, phallic, latency, and genital stages successively occur. These stages reflect the parts of the body on which sexual interest is concentrated during childhood development.... psychosexual development

Psychosocial Assessment

an interviewing technique that combines psychiatric history taking with elements of problem solving in *psychotherapy: after a psychiatric history has been elicited, the interviewer summarizes the patient’s difficulties and offers potential solutions. It is often used in patients who have presented with *deliberate self-harm, and research suggests that it offers the possibility of reducing repetition rates in such patients.... psychosocial assessment

Psychoticism

n. one of the three traits used by the British psychologist Hans Eysenck in his personality model, the others being extroversion and *neuroticism. Psychoticism is a personality pattern typified by aggressiveness and interpersonal hostility. Eysenck believed that high levels of this trait were linked to increased vulnerability to *psychosis but this has never been verified by subsequent research.... psychoticism

Psychro

combining form denoting cold.... psychro

Psychrophilic

adj. describing organisms, especially bacteria, that grow best at temperatures of 0–25°C. Compare mesophilic; thermophilic.... psychrophilic

Pterion

n. the point on the side of the skull at which the sutures between the *parietal, *temporal, and *sphenoid bones meet.... pterion

Pteroylglutamic Acid

see folate.... pteroylglutamic acid

Pterygo

combining form denoting the pterygoid process of the sphenoid bone. Example: pterygomaxillary (of the pterygoid process and the maxilla).... pterygo

Pterygoid Process

either of two large processes of the *sphenoid bone.... pterygoid process

Ptomaine

n. any of various substances produced in decaying foodstuffs and responsible for the unpleasant taste and smell of such foods. These compounds – which include putrescine, cadaverine, and neurine – were formerly thought to be responsible for food poisoning, but although they are often associated with toxic bacteria they themselves are harmless.... ptomaine

Ptsd

see post-traumatic stress disorder.... ptsd

Pttk

partial thromboplastin time with kaolin, also known as activated partial thromboplastin time (APTT): a method for estimating the degree of anticoagulation induced by heparin therapy for venous thrombosis.... pttk

Ptyal

(ptyalo-) combining form denoting saliva. Example: ptyalorrhoea (excessive flow of).... ptyal

Ptyalith

n. a stone (*calculus) in a salivary gland or duct.... ptyalith

Ptyalography

n. see sialography.... ptyalography

Pubiotomy

n. an operation to divide the pubic bone near the symphysis, the front midline where the left and right pubic bones meet. Pubiotomy is now only rarely performed during childbirth if it is necessary to increase the size of an abnormally small pelvis to allow passage of the child and a Caesarean section is contraindicated. It is occasionally also done to facilitate access to the base of the bladder and the urethra during complex urological procedures (e.g. *urethroplasty).... pubiotomy

Public Access Defibrillation Programmes

programmes of lay education in the UK that aim to provide training in cardiac resuscitation up to and including *defibrillation. Together with programmes to increase the availability of *automated external defibrillators in public places (e.g. shops and railway stations), they recognize that the best outcomes from cardiac resuscitation are obtained with early defibrillation and good bystander basic life support.... public access defibrillation programmes

Publication Ethics

the standards expected from those who write, publish, and disseminate research. The International Committee on Publication Ethics (COPE), comprising the editors and publishers of most major academic biomedical journals, consults and advises on aspects of publication ethics, such as research misconduct, plagiarism, so-called gift authorship, determination of contribution to research, and peer review processes.

A detailed guide to publication ethics from COPE... publication ethics

Public Health Consultant

(in Britain) a medical consultant with postgraduate training in public health. Formerly known as community physicians, such consultants undertake public health functions, either as *Directors of Public Health in local authorities or as consultants in public health in local authorities, *Public Health England, or elsewhere. See also public health specialist.... public health consultant

Public Health Ethics

the ethics of population (as opposed to individual) health, including issues related to epidemiology, disease prevention, health promotion, *justice, and *equality. Public health ethics is commonly concerned with the tensions between individual *autonomy and *communitarianism and/or *utilitarianism.... public health ethics

Public Health Medicine

the specialty concerned with preventing disease and improving health in populations as distinct from individuals. Formerly known as community medicine or social medicine, it includes *epidemiology, *health promotion, *health service planning, *health protection, and evaluation. See also public health consultant.... public health medicine

Public Health Service

(PHS) the oldest and one of the largest US federal health agencies. Founded in 1798 as a system of hospitals for sailors, the PHS is now the major health service operating division of the *Department of Health and Human Services and administers eleven agencies, including the *Food and Drug Administration, the National Institutes of Health, and the Substance Abuse and Mental Health Services Administration. The agency employs tens of thousands of people with a total annual budget well into the billions.... public health service

Public Health England

(PHE) an executive agency of the Department of Health and Social Care with responsibility for providing national leadership on health protection, health improvement, and public health knowledge and information. In addition to the national team, there are four regional offices and nine local centres providing public health support to *clinical commissioning groups, local authorities, and health-care providers. PHE also hosts a network of specialist and reference microbiology laboratories. It was formed as a result of the Health and Social Care Act 2012; it absorbed the functions of a number of abolished bodies, including the *Health Protection Agency, the national network of public health observatories, and the National Treatment Agency for Substance Misuse.

Public Health England website... public health england

Public Health Specialist

a public health practitioner with postgraduate training in public health or with demonstrated competence in key areas of public health practice. These specialists perform the same roles as *public health consultants but do not have medical training.... public health specialist

Public Interest Disclosure

1. the expression of concern about performance or competence that is privileged at law by virtue of the Public Interest Disclosure Act 1998. The statute provides that where an employee acts in good faith in questioning the behaviour or performance of another member of staff or an organization, he or she should be protected from such penalties as disciplinary procedures, suspension, or dismissal. See also whistle-blowing. 2. circumstances in which *confidentiality can be breached because there is a serious risk of physical harm to an identifiable individual or individuals. The basis on which confidentiality can be breached in the public interest were defined in the case of W v Egdell, in which the court held that the risk had to be of physical harm to identifiable person(s) and must not be merely ‘fanciful’. Where there is a serious risk of physical harm to a specific person, there is an entitlement but not a duty to breach confidentiality, and the *General Medical Council requires that doctors must be prepared to justify their decision either way.... public interest disclosure

Public Services Ombudsman

see Parliamentary and Health Service Ombudsman.... public services ombudsman

Pubovaginal Sling

a band of material inserted directly under the bladder neck as a treatment for women with stress *incontinence. The sling can be constructed from fascia (connective tissue) obtained from the patient or it can be synthetic. Compare tension-free vaginal tape.... pubovaginal sling

Puerperal

adj. relating to childbirth or the period that immediately follows it. See puerperium.... puerperal

Puerperal Cardiomyopathy

a rare complication of pregnancy, occurring from the sixth month of pregnancy until six months postnatally (usually within six weeks of delivery). It can follow pre-eclampsia. It is characterized by palpitations, dyspnoea, oedema (peripheral and central), and impaired exercise tolerance. The diagnosis is confirmed on echocardiography. It has a high mortality and morbidity. Treatment of heart failure, anticoagulation, and in some cases immunosuppressant therapy is required; in some cases heart transplantation may be considered.... puerperal cardiomyopathy

Puerperal Infection

infection of the female genital tract arising as a complication of childbirth. See also sepsis.... puerperal infection

Puerperal Psychosis

a *psychosis that is triggered by childbirth and usually arises in the first two weeks after giving birth. It affects 1 in 200 women; those suffering from bipolar affective disorder or schizophrenia or those who have a history of puerperal psychosis are at particularly high risk. The symptoms develop very rapidly and the patient needs to be hospitalized, ideally in a mother and baby psychiatric unit to avoid separation; most patients respond well to *antipsychotic medication.... puerperal psychosis

Puerperal Pyrexia

a temperature of 38°C occurring on any 2 days within 14 days of childbirth or miscarriage. It is an indicator of postpartum *sepsis.... puerperal pyrexia

Pulex

n. a genus of widely distributed *fleas. P. irritans, the human flea, is a common parasite whose bite may give rise to intense irritation and bacterial infection. It is an intermediate host for larvae of the tapeworms *Hymenolepis and *Dipylidium, which it can transmit to humans, and it may also be involved in the transmission of plague.... pulex

Pulfrich Phenomenon

perception of the lateral motion of an object in the visual field as having a depth component, due to a relative difference in signal timings between the two eyes. It often occurs spontaneously in several diseases affecting the eyes, such as cataract, *retrobulbar neuritis, and multiple sclerosis. [C. Pulfrich (20th century), German physicist]... pulfrich phenomenon

Pulmo

(pulmon(o)-) combining form denoting the lung(s).... pulmo

Pulmonary Artery

the artery that conveys blood from the heart to the lungs for oxygenation: the only artery in the body containing deoxygenated blood. It leaves the right ventricle and passes upwards for 5 cm before dividing into two, one branch going to each lung. Within the lungs each pulmonary artery divides into many fine branches, which end in capillaries in the alveolar walls. See also pulmonary circulation.... pulmonary artery

Pulmonary Capillary Wedge Pressure

(PCWP) an indirect measurement of the pressure of blood in the left atrium of the heart, which indicates the adequacy of left heart function. It is measured using a catheter wedged in the most distal segment of the pulmonary artery. See also Swan-Ganz catheter.... pulmonary capillary wedge pressure

Pulmonary Circulation

a system of blood vessels effecting transport of blood between the heart and lungs. Deoxygenated blood leaves the right ventricle by the pulmonary artery and is carried to the alveolar capillaries of the lungs. Gaseous exchange occurs, with carbon dioxide leaving the circulation and oxygen entering. The oxygenated blood then passes into small veins leading to the pulmonary veins, which leave the lungs and return blood to the left atrium of the heart. The oxygenated blood can then be pumped around the body via the *systemic circulation.... pulmonary circulation

Pulmonary Regurgitation

leakage of the pulmonary valve in the heart. Mild regurgitation is a common normal finding, but severe congenital pulmonary regurgitation may require surgical correction.... pulmonary regurgitation

Pulmonary Tuberculosis

see tuberculosis.... pulmonary tuberculosis

Pulmonary Valve

a valve in the heart lying between the right ventricle and the pulmonary artery. It is a *semilunar valve that prevents blood returning to the ventricle from the pulmonary artery.... pulmonary valve

Pulmonary Vein

a vein carrying oxygenated blood from the lung to the left atrium. See pulmonary circulation.... pulmonary vein

Pulp Capping

the procedure of covering an exposed tooth pulp (direct pulp cap) or nearly exposed tooth pulp (indirect pulp cap) following trauma with a medicament (usually based on calcium hydroxide), which is then covered with a temporary or permanent *restoration.... pulp capping

Pulsatile

adj. characterized by regular rhythmical beating.... pulsatile

Pulsatile Tinnitus

a form of *tinnitus that has a rhythmical quality. It may be synchronous with the heartbeat, in which case a vascular origin is likely. Pulsatile tinnitus that is not synchronous with the heartbeat may have a muscular origin due to *middle ear muscle myoclonus or *palatal myoclonus. Pulsatile tinnitus may be audible to an observer, in which case it is classified as objective pulsatile tinnitus. More often it is inaudible to others and is classified as subjective pulsatile tinnitus.... pulsatile tinnitus

Pulseless Disease

see Takayasu’s disease.... pulseless disease

Pulseless Electrical Activity

(electromechanical dissociation) the appearance of normal-looking complexes on the electrocardiogram that are, however, associated with a state of *cardiac arrest. It is usually caused by large pulmonary emboli (see pulmonary embolism), *cardiac tamponade, tension *pneumothorax, severe disturbance of body salt levels, severe haemorrhage, or hypothermia causing severe lack of oxygen to the heart muscle.... pulseless electrical activity

Pulsus Alternans

alternate variation of the force of the pulse due to variation in force of heart muscle contraction. It is a sign of cardiomyopathy and heart failure.... pulsus alternans

Pulvinar

n. the expanded posterior end of the *thalamus.... pulvinar

Punch-drunk Syndrome

a group of symptoms consisting of progressive *dementia, tremor of the hands, epilepsy, and parkinsonism. It is a consequence of repeated blows to the head that have been severe enough to cause *concussion.... punch-drunk syndrome

Pupillary Reflex

(light reflex) the reflex change in the size of the pupil according to the amount of light entering the eye. Bright light reaching the retina stimulates nerves of the *parasympathetic nervous system, which cause the pupil to contract. In dim light the pupil opens, due to stimulation of the *sympathetic nervous system. See also iris.... pupillary reflex

Pupilloplasty

n. a surgical procedure to alter the shape or function of the pupil. It is usually performed to repair a pupil damaged after trauma.... pupilloplasty

Pupps

see polymorphic eruption of pregnancy.... pupps

Pure Tone Audiogram

(PTA) see audiogram.... pure tone audiogram

Purgation

n. the use of drugs to stimulate intestinal activity and clear the bowels. See laxative.... purgation

Purkinje Fibres

see atrioventricular bundle.... purkinje fibres

Purtscher’s Retinopathy

damage to the retina associated with severe head injuries. It can also occur with other types of trauma, such as long-bone fractures, and with several nontraumatic systemic diseases. [O. Purtscher (1852–1927), Austrian ophthalmologist]... purtscher’s retinopathy

Push-bang Technique

a technique for removing a stone from the ureter. It consists of ‘pushing’ the stone back into the renal pelvis, where it can be destroyed by *lithotripsy (‘bang’).... push-bang technique

Putamen

n. a part of the lenticular nucleus (see basal ganglia).... putamen

Putrescine

n. an amine formed during *putrefaction.... putrescine

Pyarthrosis

n. an infected joint filled with pus (see septic arthritis).... pyarthrosis

Pyel

(pyelo-) combining form denoting the pelvis of the kidney. Example: pyelectasis (dilation of).... pyel

Pyelocystitis

n. inflammation of the renal pelvis and urinary bladder (see pyelitis; cystitis).... pyelocystitis

Pyeloplasty

n. an operation to relieve obstruction at the junction of the pelvis of the kidney and the ureter. The procedure is often performed laparoscopically. The narrowed segment may be excised and the renal pelvis and ureteric ends anastomosed or a flap of tissue from the renal pelvis may be folded down to widen the narrowing. A ureteric stent is left in place while healing takes place. See hydronephrosis; Dietl’s crisis.... pyeloplasty

Pyelotomy

n. surgical incision into the pelvis of the kidney. This operation is usually undertaken to remove a stone (see pyelolithotomy) but is also necessary when surgical drainage of the kidney is required by a catheter or tube.... pyelotomy

Pyemotes

n. see Pediculoides.... pyemotes

Pykno

combining form denoting thickness or density.... pykno

Pyknosis

n. the process in which the cell nucleus is thickened into a dense mass, which occurs when cells die. —pyknotic adj.... pyknosis

Pylethrombosis

n. obstruction of the portal vein by a blood clot (see thrombosis). It can result from infection of the umbilicus in infants, pylephlebitis, cirrhosis of the liver, and liver tumours. *Portal hypertension is a frequent result.... pylethrombosis

Pyll

see years of life lost.... pyll

Pylor

(pyloro-) combining form denoting the pylorus. Example: pyloroduodenal (of the pylorus and duodenum).... pylor

Pylorectomy

n. a surgical operation that involves the removal of the distal part of the stomach (*pylorus). See antrectomy; pyloroplasty.... pylorectomy

Pyocele

n. a swelling caused by an accumulation of pus in a part of the body.... pyocele

Pyocolpos

n. the presence of pus in the vagina.... pyocolpos

Pyocyanin

n. an antibiotic substance produced by the bacterium *Pseudomonas aeruginosa and active principally against Gram-positive bacteria.... pyocyanin

Pyogenic Arthritis

see septic arthritis.... pyogenic arthritis

Pyometra

n. the presence of pus in the uterus.... pyometra

Pyometritis

n. inflammation of the uterus, with the formation of pus.... pyometritis

Pyomyositis

n. bacterial or fungal infection of a muscle resulting in painful inflammation.... pyomyositis

Pyonephrosis

n. obstruction and infection of the kidney resulting in pus formation. A kidney stone is the usual cause of the obstruction, and the kidney becomes distended by pus and destroyed by the inflammation, which extends into the kidney substance itself and sometimes into the surrounding tissues (see perinephritis). Treatment is urgent *nephrectomy under antibiotic cover.... pyonephrosis

Pyopneumothorax

n. pus and gas or air in the *pleural cavity. The condition can arise if gas is produced by gas-forming bacteria as part of an *empyema or if air is introduced during attempts to drain the pus from an empyema. Alternatively a *hydropneumothorax may become infected.... pyopneumothorax

Pyosalpingitis

n. inflammation of a Fallopian tube, with the formation of pus.... pyosalpingitis

Pyosalpingo-oophoritis

n. inflammation of an ovary and Fallopian tube, with the formation of pus.... pyosalpingo-oophoritis

Pyosalpinx

n. the accumulation of pus in a Fallopian tube.... pyosalpinx

Pyosis

n. the formation and discharge of pus.... pyosis

Pyothorax

n. see empyema.... pyothorax

Pyramid

n. 1. one of the conical masses that make up the medulla of the *kidney, extending inwards from a base inside the cortex towards the pelvis of the kidney. 2. one of the elongated bulging areas on the anterior surface of the *medulla oblongata in the brain, extending downwards to the spinal cord. 3. one of the divisions of the vermis of the *cerebellum in the middle lobe. 4. a protrusion of the medial wall of the vestibule of the middle ear.... pyramid

Pyramidal Cell

a type of neuron found in the *cerebral cortex, with a pyramid-shaped cell body, a branched dendrite extending from the apex towards the brain surface, several dendrites extending horizontally from the base, and an axon running in the white matter of the hemisphere.... pyramidal cell

Pyramidal System

a collection of nerve fibres in the central nervous system that extend from the *motor cortex in the brain to the spinal cord and are responsible for initiating movement. In the medulla oblongata the fibres form a *pyramid (hence the name), within which they cross from one side of the brain to the opposite side of the spinal cord; this is called the decussation of the pyramids. Damage to the pyramidal system manifests in a specific pattern of weakness in the face, arms, and legs, abnormally brisk reflexes, and an extensor *plantar reflex (Babinski response).... pyramidal system

Pyret

(pyreto-) combining form denoting fever.... pyret

Pyridostigmine

n. an *anticholinesterase drug used in the treatment of *myasthenia gravis. Side-effects may include nausea, vomiting, abdominal pain, diarrhoea, sweating, and increased salivation.... pyridostigmine

Pyridoxal Phosphate

a derivative of vitamin B6 that is an important *coenzyme in certain reactions of amino-acid metabolism. See transamination.... pyridoxal phosphate

Pyrimidine

n. a nitrogen-containing compound with a ring molecular structure. The commonest pyrimidines are cytosine, thymine, and uracil, which form the *nucleotides of nucleic acids.... pyrimidine

Pyruvic Acid

(pyruvate) a compound, derived from carbohydrates, that may be oxidized via a complex series of reactions in the *Krebs cycle to yield carbon dioxide and energy in the form of ATP.... pyruvic acid

Radiation Protection

measures designed to limit the dose of harmful radiation to patients and workers. Medical exposure to radiation is governed in the UK by the Department of Health and Social Care under the Ionising Radiation (Medical Exposures) Regulations 2000 (IRMER). A guiding theme of protection is the ALARA principle (“as low as reasonably achievable”).... radiation protection

Radiofrequency Palatal Myoplasty

(RPM) see palatoplasty.... radiofrequency palatal myoplasty

Randall’s Plaque

the initial deposit of calcium-loaded material on a renal *pyramid that develops into a kidney stone. [A. Randall (1883–1951), US urologist]... randall’s plaque

Rathke’s Pouch

see craniopharyngioma.... rathke’s pouch

Reflective Practice

the process of critically considering one’s own professional practice during or after events in order to review one’s values and to understand the emotions and reasons behind one’s actions and decisions and the effect of those actions and decisions on others. Reflection is seen as essential to developing and maintaining ethical medical practice. See autonomy.... reflective practice

Refractory Period

(in neurology) the time of recovery needed for a nerve cell that has just transmitted a nerve impulse or for a muscle fibre that has just contracted. During the refractory period a normal stimulus will not bring about excitation of the cell, which is undergoing *repolarization.... refractory period

Response Prevention

a form of *behaviour therapy given for severe *obsessions. Patients are encouraged to abstain from rituals and repetitive acts while they are in situations that arouse anxiety. For example, a hand-washing ritual might be treated by stopping washing while being progressively exposed to dirt. The anxiety then declines, and with it the obsessions.... response prevention

Rest Pain

pain without prior exertion, usually experienced in the feet or chest (*angina pectoris), that indicates an extreme degree of *ischaemia.... rest pain

Rhesus Prophylaxis

see anti-D immunoglobulin; haemolytic disease of the newborn.... rhesus prophylaxis

Robotic Prostatectomy

see prostatectomy.... robotic prostatectomy

R On T Phenomenon

(in *electrocardiography) the superimposition of an R wave (ventricular *depolarization) on the T wave (ventricular *repolarization) of the preceding heartbeat. It may trigger ventricular fibrillation. See QRS complex; Q–T interval; S–T segment.... r on t phenomenon

Salvage Procedure

surgical measures to palliate the worst effects of a tumour but with no aim to effect a cure.... salvage procedure

Schizoid Personality

a personality characterized by solitariness, emotional coldness to others, inability to experience pleasure, lack of response to praise and criticism, withdrawal into a fantasy world, excessive introspection, and eccentricity of behaviour. See personality disorder.... schizoid personality

Schizotypal Personality Disorder

a personality disorder characterized by cold aloof feelings, eccentricities of behaviour, odd ways of thinking and talking, and occasional short periods of intense illusions, hallucinations, or delusion-like ideas.... schizotypal personality disorder

Schönlein–henoch Purpura

see Henoch–Schönlein purpura.... schönlein–henoch purpura

Sestamibi Parathyroid Scan

(in *nuclear medicine) a scan that can help to localize the site of a parathyroid adenoma before surgical removal, to treat primary *hyperparathyroidism. The tracer is technetium-99m-labelled sestamibi (a small protein), which is selectively absorbed by overactive parathyroid glands.... sestamibi parathyroid scan

Shaking Palsy

an archaic name for Parkinson’s disease (see parkinsonism).... shaking palsy

Sims’s Position

the left-sided knees-up position commonly assumed by patients undergoing examinations of the anus and rectum or vagina. [J. M. Sims (1813–83), US gynaecologist]... sims’s position

Single-payer System

a type of health-care system in which there is only one purchaser of health-care services, usually the government. The NHS is a single-payer system.... single-payer system

Single Photon Emission Computed Tomography

see SPECT scanning.... single photon emission computed tomography

Sling Procedure

any of a group of surgical procedures for treating stress incontinence in women. See colposuspension; pubovaginal sling; tension-free vaginal tape.... sling procedure

Spontaneous Bacterial Peritonitis

(SBP) the presence of infection in the abdominal cavity without an obvious cause (see peritonitis). SBP occurs in patients with liver disease (and occasionally in those with nephrotic syndrome) due to *portal hypertension. This leads to the build-up of large volumes of peritoneal fluid (*ascites) in which infection takes hold and propagates. Patients experience fever, nausea, abdominal pain, further accumulation of ascites, and they may develop *hepatic encephalopathy with rapid deterioration. Diagnosis is made by *paracentesis culture of the ascitic fluid to confirm the presence of bacteria. Treatment includes antibiotics.... spontaneous bacterial peritonitis

Strassman Procedure

an operation to correct a double uterus (see uterus didelphys). It has now largely been replaced by hysteroscopic techniques. [P. F. Strassman (1866–1938), German obstetrician and gynaecologist]... strassman procedure

Studer Pouch

see cystectomy.... studer pouch

Styloid Process

1. a long slender downward-pointing spine projecting from the lower surface of the *temporal bone of the skull. It provides attachment for muscles and ligaments of the tongue and hyoid bone. 2. any of various other spiny projections; occurring, for example, at the lower ends of the ulna and radius.... styloid process

Symphysis Pubis Dysfunction

(SPD) pain in the region of the pelvic girdle, most commonly over the pubic bone in the front or in the lower back and usually caused by excessive movement of the symphysis pubis and other pelvic joints. This is common during pregnancy, hence the condition is also called pregnancy-related pelvic girdle pain (PPGP). Treatment is usually with physiotherapy.... symphysis pubis dysfunction

Tabo-paresis

n. a late effect of syphilitic infection of the nervous system in which the patient shows features of *tabes dorsalis and *general paralysis of the insane.... tabo-paresis

Third-party Payer

the source of payment for hospital or medical services when this is neither the patient (directly) nor the health-care provider. A third-party payer may be the government, an insurance company, an employer, or a philanthropic organization.... third-party payer

Therapeutic Privilege

the entitlement of a doctor to withhold information from a patient when it is feared that disclosure could cause immediate and serious harm to the patient (e.g. because he or she is suffering from severe depression). In exceptional cases, the need to withhold information may be considered to override the requirement to obtain informed *consent before proceeding with treatment. In such a case therapeutic privilege could be used as a legal defence against the charge of *battery or *negligence. If doctors are intending to invoke the concept of therapeutic privilege they must be prepared to justify their decision. Furthermore, while it was once quite common for doctors to withhold bad news or upsetting information from patients for *paternalistic motives, it is now considered a breach of the patient’s *autonomy and the ethicolegal justification for invoking therapeutic privilege where a patient has *capacity is, if it exists at all, extremely limited.... therapeutic privilege

Thrombotic Thrombocytopenic Purpura

(TTP) a rare disorder of coagulation caused by deficiency or inhibition of *ADAMTS13, a protein that is responsible for breaking down von Willebrand factor (see von Willebrand’s disease). This results in haemolytic *anaemia, *thrombocytopenia, and fluctuating neurological abnormalities. It is treated by *plasmapheresis.... thrombotic thrombocytopenic purpura

Thyrotoxic Periodic Paralysis

a condition in which attacks of sudden weakness and flaccidity occur in patients with *thyrotoxicosis, seen most often in males of Asian descent. The attacks last from hours to days; they can be prevented by potassium supplements and subsequent treatment of the thyrotoxicosis.... thyrotoxic periodic paralysis

Tissue-type Plasminogen Activator

(tPA, TPA) a natural protein, found in the body and able to be manufactured by genetic engineering, that can break up a thrombus (see thrombolysis). It requires the presence of *fibrin as a cofactor and is able to activate *plasminogen on the fibrin surface, which distinguishes it from the other plasminogen activators, *streptokinase and *urokinase. tPAs include reteplase and tenecteplase, given to treat acute myocardial infarction, and *alteplase.... tissue-type plasminogen activator

Tonic Pupil

(Adie’s pupil) a pupil that is dilated as a result of damage to the nerves supplying the ciliary muscle and iris. It reacts poorly to light but may constrict better for near vision, with slow redilation on refixation at a distance. The tonic pupil is sensitive to dilute 0.1% pilocarpine drops, which cause marked constriction but have little effect on a normal pupil. The tonic pupil may become miotic (see miosis) over time.... tonic pupil

Torkildsen Procedure

an operation in which a *shunt is created between the lateral *ventricle of the brain and the *cisterna magna to bypass a block of the cerebral *aqueduct and thus relieve *hydrocephalus. Originally this was achieved by means of an external indwelling catheter, but later techniques use an internal catheter, which reduces the risk of septic complications. [A. Torkildsen (20th century), Norwegian neurosurgeon]... torkildsen procedure

Torsades De Pointes

a very dangerous form of *ventricular tachycardia characterized by a sinusoidal (twisting) pattern on the electrocardiogram due to a constantly shifting cardiac electrical vector (hence the French term, meaning ‘twisting of points’). It is usually a side-effect of medication but may also occur in patients with severe deficiency of potassium or magnesium or inherited abnormalities of the cardiac electrical system. See long QT syndrome.... torsades de pointes

Torus Palatinus

A benign bony growth that develops on the palate, most commonly on the midline.... torus palatinus

Total Parenteral Nutrition

(TPN) the delivery of all the essential nutrients directly into the bloodstream through a catheter in a vein. This may be by the peripheral route, via a vein in the upper arm (see PICC line) for short-term use (see peripheral parenteral nutrition), or centrally, into the subclavian vein in the neck (see Hickman catheter), for longer than two weeks. TPN has a risk of complications and should only be used when the gastrointestinal tract is not functioning. *Enteral feeding is always the preferred route. See also artificial nutrition and hydration; nutrition.... total parenteral nutrition

Towne’s Projection

a *posteroanterior X-ray film to show the entire skull and mandible. [E. B. Towne (1883–1957), US otolaryngologist]... towne’s projection

Transseptal Puncture

a procedure in which, under X-ray guidance, a sharp-tipped catheter positioned in the heart is used to create a small hole in the partition (septum) separating the atria. This allows other catheters to be passed from the right to the left atrium for the purposes of pressure measurement, *ablation, or *valvuloplasty.... transseptal puncture

Transurethral Resection Of The Prostate

(TURP) see resection.... transurethral resection of the prostate

Transurethral Vaporization Of The Prostate

(TUVP) a technique that vaporizes (rather than resects) prostate tissue; it is associated with less bleeding during the procedure. TUVP is used to treat *lower urinary tract symptoms thought to be due to benign prostatic hyperplasia (see prostate gland) or urinary retention.... transurethral vaporization of the prostate

Transverse Process

the long projection from the base of the neural arch of a *vertebra.... transverse process

Trendelenburg Position

a special operating-table posture for patients undergoing surgery of the pelvis or for patients suffering from shock to reduce blood loss in operations on the legs. The patient is laid on his or her back with the pelvis higher than the head, inclined at an angle of about 45°. [F. Trendelenburg (1844–1924), German surgeon]... trendelenburg position

Trespass Against The Person

see battery.... trespass against the person

Tullio Phenomenon

dizziness induced by exposure to sound. It is seen in various conditions of the inner ear, including *Ménière’s disease and *superior canal dehiscence syndrome. [P. Tullio (1881–1941), Italian biologist]... tullio phenomenon

Twin-peak Sign

see lambda sign.... twin-peak sign

Uhthoff Phenomenon

the worsening of neurological symptoms, including vision, in demyelinating conditions such as multiple sclerosis, when the body becomes overheated in hot weather or by exercise, fever, or saunas and hot tubs. [W. Uhthoff (1853–1927), German ophthalmologist]... uhthoff phenomenon

Usual Interstitial Pneumonia

(UIP) see interstitial pneumonia; idiopathic pulmonary fibrosis.... usual interstitial pneumonia

Variable Positive Airways Pressure

see BiPAP.... variable positive airways pressure

Vasa Praevia

an uncommon but potentially disastrous complication of delivery, occurring in about 1 in 5000 deliveries, when unprotected fetal vessels run across the *lower uterine segment and cervix in front of the presenting part of the fetus. It is associated with a velamentous insertion of the cord (where the umbilical cord inserts directly into the membranes rather than the placenta) and in cases with normal cord insertion when the vessels run between the two lobes of a bilobed placenta. Vessels unsupported by placental tissue or the umbilical cord can tear when the cervix dilates or the membranes rupture, causing rapid fetal haemorrhage. Immediate Caesarean section to save the baby from *exsanguination is indicated. Fetal mortality for cases not recognized before the onset of labour is very high; appropriate use of prenatal ultrasonography may prevent perinatal death.... vasa praevia

Vasoactive Intestinal Peptide

see VIP.... vasoactive intestinal peptide

Vault Prolapse

prolapse of the *fornix (vault) of the vagina, which occurs at the time of hysterectomy (vaginal or abdominal) when the superior vaginal support mechanism is disrupted. It can be surgically corrected (see sacrocolpopexy; uterosacral suspension).... vault prolapse

Ventilation-perfusion Scanning

(V/Q scanning) a nuclear medicine technique in which two different isotopes are used, one inhaled (usually *xenon-133 or *krypton-81m), to examine lung ventilation, and the other injected into a vein, to examine lung perfusion. In *pulmonary embolism, the area of lung supplied by the blocked artery is not being perfused with blood – which gives a perfusion defect on the film – but has normal ventilation. This technique is highly sensitive for pulmonary embolism.... ventilation-perfusion scanning

Vestibular Evoked Myogenic Potential Test

(VEMP) a test used to measure the response of the *saccule. It is used in the diagnosis of *superior canal dehiscence syndrome, *Ménière’s disease, and other disorders of the inner ear.... vestibular evoked myogenic potential test

Visceral Pouch

see pharyngeal pouch.... visceral pouch

Visual Pathway

see optic nerve.... visual pathway

Visual Purple

see rhodopsin.... visual purple

Waters’ Projection

a *posteroanterior X-ray film to show the maxillae, maxillary sinuses, and zygomatic bones. [C. A. Waters (1888–1961), US radiologist]... waters’ projection

Windigo Psychosis

a delusion of having been transformed into a windigo, a mythical monster that eats human flesh. It is often quoted as an example of a culture-specific syndrome (confined to certain North American Indian tribes).... windigo psychosis

Pappus

the calyx in a composite flower having feathery hairs, scales or bristles.... pappus

Parturient

aiding childbirth.... parturient

Perennial

a plant which lives for more than two years, normally flowering every year.... perennial

Physiological

describes the natural biological processes of a living organism.... physiological

Wolff–parkinson–white Syndrome

a congenital abnormality of heart conduction caused by the presence of an *accessory pathway of conduction between the atria and ventricles. It results in premature excitation of one ventricle and is characterized by an abnormal wave (delta wave) at the start of the QRS complex on the electrocardiogram. The accessory pathway predisposes the patient to episodes of fast heart rate due to the rapid self-sustaining circulation of an electrical impulse from the atria to the ventricles and back again (*atrioventricular reciprocating tachycardia). Emergency treatment is in the form of drugs that temporarily block the re-entry circuit. Permanent destruction of the accessory pathway by *radiofrequency ablation is usually curative. [L. Wolff; Sir J. Parkinson (1885–1976), British physician; P. D. White (1886–1973), US cardiologist]... wolff–parkinson–white syndrome

Eucalyptus, Broad-leaved Peppermint

Eucalyptus dives var. Type

FAMILY: Myrtaceae

SYNONYMS: Broad-leaf peppermint, blue peppermint, menthol-scented gum.

GENERAL DESCRIPTION: A robust, medium-sized eucalyptus tree, with a short trunk, spreading branches and fibrous grey bark. The young leaves are blue and heart-shaped, the mature leaves are very aromatic, thick and tapering at both ends.

DISTRIBUTION: Native to Tasmania and Australia, especially New South Wales and Victoria. Oil is also produced in South Africa.

OTHER SPECIES: There are two types of broad-leaved peppermint although they look identical – one is rich in cineol (E. dives var. C.) and one is rich in ‘piperitone’ (E. dives var. Type). It is also similar to the peppermint eucalyptus (E. piperita) and the grey or narrow-leaved peppermint (E. radiata var. phellandra). See also entry on Eucalyptus, blue gum and Botanical Classification section.

HERBAL/FOLK TRADITION: The aborigines used the burning leaves in the form of a fumigation for the relief of fever; ‘heat went out of sick man and into fire’.

ACTIONS: See Eucalyptus, blue gum.

EXTRACTION: Essential oil by steam distillation from the leaves and twigs.

CHARACTERISTICS: A colourless or pale yellow mobile liquid with a fresh, camphoraceous, spicy-minty odour.

PRINCIPAL CONSTITUENTS: Piperitone (40–50 per cent), phellandrene (20–30 per cent), camphene, cymene, terpinene and thujene, among others. It is sold as Grades A, B or C according to the exact balance of constituents.

SAFETY DATA: Non-toxic, non-irritant (in dilution), non-sensitizing. Eucalyptus oil is toxic if taken internally (see entry on eucalyptus blue gum).

AROMATHERAPY/HOME: USE

Skin Care: Cuts, sores, ulcers etc.

Circulation muscles and joints: Arthritis, muscular aches and pains, rheumatism, sports injuries, sprains, etc.

Respiratory System: Asthma, bronchitis, catarrh, coughs, throat and mouth infections, etc.

Immune System: Colds, fevers, ’flu, infectious illness, e.g. measles.

Nervous System: Headaches, nervous exhaustion, neuralgia, sciatica.

OTHER USES: Little used medicinally these days except in deodorants, disinfectants, mouthwashes, gargles and in veterinary practice. ‘Piperitone’ rich oils are used in solvents. Employed for the manufacture of thymol and menthol (from piperitone).

EUCALYPTUS, ... eucalyptus, broad-leaved peppermint

Palmarosa

Cymbopogon martinii var. martinii

FAMILY: Graminaceae

SYNONYMS: Andropogon martinii, A. martinii var. motia, East Indian geranium, Turkish geranium, Indian rosha, motia.

GENERAL DESCRIPTION: A wild-growing herbaceous plant with long slender stems and terminal flowering tops; the grassy leaves are very fragrant.

DISTRIBUTION: Native to India and Pakistan; now grown in Africa, Indonesia, Brazil and the Comoro Islands.

OTHER SPECIES: Of the same family as lemongrass and citronella; also closely related to gingergrass which is a different chemotype known as C. martinii var. sofia. Gingergrass is considered an inferior oil but in some parts of India the two types of grass are distilled together.

HERBAL/FOLK TRADITION: ‘The oil term “Indian” or “Turkish” geranium oil, which formerly was applied to palmarosa oil, dates back to the time when the oil was shipped from Bombay to ports of the Red Sea and transported partly by land, to Constantinople and Bulgaria, where the oil was often used for the adulteration of rose oil.’.

ACTIONS: Antiseptic, bactericidal, cicatrisant, digestive, febrifuge, hydrating, stimulant (digestive, circulatory), tonic.

EXTRACTION: Essential oil by steam or water distillation of the fresh or dried grass.

CHARACTERISTICS: A pale yellow or olive liquid with a sweet, floral, rosy, geranium-like scent. It blends well with cananga, geranium, oakmoss, rosewood, amyris, sandalwood, guaiacwood, cedarwood and floral oils.

PRINCIPAL CONSTITUENTS: Mainly geraniol; also farnesol, geranyl acetate, methyl heptenone, citronellol, citral, dipentene and limonene, among others. Several chemotypes depending upon source – the cultivated varieties are considered of superior quality.

SAFETY DATA: Non-toxic, non-irritant, non-sensitizing.

AROMATHERAPY/HOME: USE

Skin care: Acne, dermatitis and minor skin infections, scars, sores, wrinkles; valuable for all types of treatment for the face, hands, feet, neck and lips (moisturizes the skin, stimulates cellular regeneration, regulates sebum production).

Digestive system: Anorexia, digestive atonia, intestinal infections – ‘This is an essence which acts on the pathogenic intestinal flora, in particular on the coli bacillus, the Eberth bacillus and the bacillus of dysentery ... this essence favours the transmutation of the pathogenic agent into normal cells of intestinal mucous membranes. Thus it arrests the degeneracy of the cells for the latter, swiftly impels groups of normal cells towards an inferior form in their hierarchy. The essence does not appear to contain any acid.’.

Nervous system: Nervous exhaustion, stressrelated conditions.

OTHER USES: Used extensively as a fragrance component in cosmetics, perfumes and especially soaps due to excellent tenacity. Limited use as a flavouring agent, e.g. tobacco. Used for the isolation of natural geraniol.... palmarosa

Phytohormones

plant substances that mimic the action of human hormones.... phytohormones

Pomade

a prepared perfume material obtained by the enfleurage process.... pomade

Pruritis

itching.... pruritis

Mint, Peppermint

Mentha piperita

FAMILY: Lamiaceae (Labiatae)

SYNONYMS: Brandy mint, balm mint.

GENERAL DESCRIPTION: A perennial herb up to 1 metre high with underground runners by which it is easily propagated. The ‘white’ peppermint has green stems and leaves; the ‘black’ peppermint has dark green serrated leaves, purplish stems and reddish-violet flowers.

DISTRIBUTION: Originally a cultivated hybrid between M. viridis and M. aquatica, known to have been propagated from before the seventeenth century in England. Naturalized throughout Europe and America, it is cultivated worldwide. The oil is produced mainly in France, England, America, Russia, Bulgaria, Italy, Hungary, Morocco and China.

OTHER SPECIES: There are several different strains or chemotypes of peppermint. In addition there are numerous other species of mint, such as spearmint, apple mint, pennyroyal, water mint and pineapple mint – some of which are used to produce essential oils (see Botanical Classification section). Peppermints grown in northern regions, including the Mitcham peppermint, are considered of superior quality.

HERBAL/FOLK TRADITION: Mints have been cultivated since ancient times in China and Japan. In Egypt evidence of a type of peppermint has been found in tombs dating from 1000 BC. It has been used extensively in Eastern and Western medicine for a variety of complaints, including indigestion, nausea, sore throat, diarrhoea, headaches, toothaches and cramp.

It is current in the British Herbal Pharmacopoeia for intestinal colic, flatulence, common cold, vomiting in pregnancy and dysmenorrhoea.

ACTIONS: Analgesic, anti-inflammatory, antimicrobial, antiphlogistic, antipruritic, antiseptic, antispasmodic, antiviral, astringent, carminative, cephalic, cholagogue, cordial, emmenagogue, expectorant, febrifuge, hepatic, nervine, stomachic, sudorific, vasoconstrictor, vermifuge.

EXTRACTION: Essential oil by steam distillation from the flowering herb (approx. 3–4 per cent yield).

CHARACTERISTICS: A pale yellow or greenish liquid with a highly penetrating, grassy-minty camphoraceous odour. It blends well with benzoin, rosemary, lavender, marjoram, lemon, eucalyptus and other mints.

PRINCIPAL CONSTITUENTS: Menthol (29–48 per cent), menthane (20–31 per cent), menthyl acetate, menthofuran, limonene, pulegone, cineol, among others.

SAFETY DATA: Non-toxic, non-irritant (except in concentration), possible sensitization due to menthol. Use in moderation.

AROMATHERAPY/HOME: USE

Skin care: Acne, dermatitis, ringworm, scabies, toothache.

Circulation muscles and joints: Neuralgia, muscular pain, palpitations.

Respiratory system: Asthma, bronchitis, halitosis, sinusitis, spasmodic cough – ‘When inhaled (in steam) it checks catarrh temporarily, and will provide relief from head colds and bronchitis: its antispasmodic action combines well with this to make it a most useful inhalation in asthma.’.

Digestive system: Colic, cramp, dyspepsia, flatulence, nausea.

Immune system: Colds, ’flu, fevers.

Nervous system: Fainting, headache, mental fatigue, migraine, nervous stress, vertigo.

OTHER USES: Flavouring agent in pharmaceuticals, and ingredient in cough, cold and digestive remedies. Flavouring agent in many foods, especially chewing gum and sweets, alcoholic and soft drinks; also widely used to flavour tobacco. Fragrance component in soaps, toothpaste, detergents, cosmetics, colognes and perfumes.... mint, peppermint

Patchouli

Pogostemon cablin

FAMILY: Lamiaceae (Labiatae)

SYNONYMS: P. patchouly, patchouly, puchaput.

GENERAL DESCRIPTION: A perennial bushy herb up to 1 metre high with a sturdy, hairy stem, large, fragrant, furry leaves and white flowers tinged with purple.

DISTRIBUTION: Native to tropical Asia, especially Indonesia and the Philippines. It is extensively cultivated for its oil in its native regions as well as India, China, Malaysia and South America. The oil is also distilled in Europe and America from the dried leaves.

OTHER SPECIES: Closely related to the Java patchouli (P. heyneanus), also known as false patchouli, which is also occasionally used to produce an essential oil.

HERBAL/FOLK TRADITION: The oil is used in the East generally to scent linen and clothes, and is believed to help prevent the spread of disease (prophylactic). In China, Japan and Malaysia the herb is used to treat colds, headaches, nausea, vomiting, diarrhoea, abdominal pain and halitosis. In Japan and Malaysia it is used as an antidote to poisonous snakebites.

ACTIONS: Antidepressant, anti-inflammatory, anti-emetic, antimicrobial, antiphlogistic, antiseptic, antitoxic, antiviral, aphrodisiac, astringent, bactericidal, carminative, cicatrisant, deodorant, digestive, diuretic, febrifuge, fungicidal, nervine, prophylactic, stimulant (nervous), stomachic, tonic.

EXTRACTION: Essential oil by steam distillation of the dried leaves (usually subjected to fermentation previously). A resinoid is also produced, mainly as a fixative.

CHARACTERISTICS: An amber or dark orange viscous liquid with a sweet, rich, herbaceous earthy odour – it improves with age. It blends well with labdanum, vetiver, sandalwood, cedarwood, oakmoss, geranium, clove, lavender, rose, neroli, bergamot, cassia, myrrh, opopanax, clary sage and oriental-type bases.

PRINCIPAL CONSTITUENTS: Patchouli alcohol (40 per cent approx.), pogostol, bulnesol, nor patchoulenol, bulnese, patchoulene, among others.

SAFETY DATA: Non-toxic, non-irritant, non-sensitizing.

AROMATHERAPY/HOME: USE

Skin care: Acne, athlete’s foot, cracked and chapped skin, dandruff, dermatitis, eczema (weeping), fungal infections, hair care, impetigo, insect repellent, sores, oily hair and skin, open pores, wounds, wrinkles.

Nervous system: Frigidity, nervous exhaustion and stress-related complaints.

OTHER USES: Extensively used in cosmetic preparations, and as a fixative in soaps and perfumes, especially oriental types. Extensively used in the food industry, in alcoholic and soft drinks. It makes a good masking agent for unpleasant tastes and smells.... patchouli

Pepper, Black

Piper nigrum

FAMILY: Piperaceae

SYNONYMS: Piper, pepper.

GENERAL DESCRIPTION: A perennial woody vine up to 5 metres high with heart-shaped leaves and small white flowers. The berries turn from red to black as they mature – black pepper is the dried fully grown unripe fruit.

DISTRIBUTION: Native to south west India; cultivated extensively in tropical countries. Major producers are India, Indonesia, Malaysia, China and Madagascar. It is also distilled in Europe and America from the imported dried fruits.

OTHER SPECIES: The so-called white pepper is the dried ripe fruit with the outer pericarp removed. Not to be confused with cayenne pepper or paprika from the capsicum species, which are used to make an oleoresin.

HERBAL/FOLK TRADITION: Both black and white pepper have been used in the East for over 4000 years for medicinal and culinary purposes. In Chinese medicine, white pepper is used to treat malaria, cholera, dysentery, diarrhoea, stomach ache and other digestive problems. In Greece it is used for intermittent fever and to fortify the stomach. ‘The mendicant monks of India who cover daily considerable distances on foot, swallow 7–9 grains of pepper a day. This gives them remarkable endurance.’.

ACTIONS: Analgesic, antimicrobial, antiseptic, antispasmodic, antitoxic, aperitif, aphrodisiac, bactericidal, carminative, diaphoretic, digestive, diuretic, febrifuge, laxative, rubefacient, stimulant (nervous, circulatory, digestive), stomachic, tonic.

EXTRACTION: Essential oil by steam distillation from the black peppercorns, dried and crushed. (‘Light’ and ‘heavy’ oils are produced by the extraction of the low or high boiling fractions respectively.) An oleoresin is also produced by solvent extraction, mainly for flavour use.

CHARACTERISTICS: A water-white to pale olive mobile liquid with a fresh, dry-woody, warm, spicy scent. It blends well with frankincense, sandalwood, lavender, rosemary, marjoram, spices and florals (in minute quantities).

PRINCIPAL CONSTITUENTS: Mainly monoterpenes (70–80 per cent): thujene, pinene, camphene, sabinene, carene, myrcene, limonene, phellandrene, and sesquiterpenes (20–30 per cent) and oxygenated compounds.

SAFETY DATA: Non-toxic, non-sensitizing, irritant in high concentration due to rubefacient properties. Use in moderation only.

AROMATHERAPY/HOME: USE

Skin care: Chilblains.

Circulation muscles and joints: Anaemia, arthritis, muscular aches and pains, neuralgia, poor circulation, poor muscle tone (muscular atonia), rheumatic pain, sprains, stiffness.

Respiratory system: Catarrh, chills.

Digestive system: Colic, constipation, diarrhoea, flatulence, heartburn, loss of appetite, nausea.

Immune system: Colds, ’flu, infections and viruses.

OTHER USES: Used in certain tonic and rubefacient preparations. Used for unusual effects in perfumery work; for example, with rose or carnation in oriental or floral fragrances. The oil and oleoresin are used extensively in the food industry, as well as in alcoholic drinks.... pepper, black

Petitgrain

Citrus aurantium var. amara

FAMILY: Rutaceae

SYNONYMS: C. bigaradia, petitgrain bigarade (oil), petitgrain Paraguay (oil). See also bitter orange.

GENERAL DESCRIPTION: The oil of petitgrain is produced from the leaves and twigs of the same tree that produces bitter orange oil and neroli oil: see bitter orange and neroli.

DISTRIBUTION: Native to southern China and north east India. The best quality petitgrain oil comes from France but a good-quality oil is also produced in North Africa, Paraguay and Haiti from semi-wild trees.

OTHER SPECIES: A type of petitgrain is also produced in small quantities from the leaves, twigs and small unripe fruit of the lemon, sweet orange, mandarin and bergamot trees.

HERBAL/FOLK TRADITION: At one time the oil used to be extracted from the green unripe oranges when they were still the size of a cherry – hence the name petitgrains or ‘little grains’. One of the classic ingredients of eau-de-cologne.

ACTIONS: Antiseptic, antispasmodic, deodorant, digestive, nervine, stimulant (digestive, nervous), stomachic, tonic.

EXTRACTION: Essential oil by steam distillation from the leaves and twigs. An orange ‘leaf and flower’ water absolute is also produced, known as petitgrain sur fleurs.

CHARACTERISTICS: A pale yellow to amber liquid with a fresh-floral citrus scent and a woody-herbaceous undertone. It blends well with rosemary, lavender, geranium, bergamot, bitter orange, labdanum, neroli, oakmoss, clary sage, jasmine, benzoin, palmarosa, clove and balsams.

PRINCIPAL CONSTITUENTS: 40–80 per cent esters: mainly linalyl acetate and geranyl acetate, as well as linalol, nerol, terpineol, geraniol, nerolidol, farnesol, limonene, among others.

SAFETY DATA: Non-toxic, non-irritant, nonsensitizing, non-phototoxic.

AROMATHERAPY/HOME: USE

Skin care: Acne, excessive perspiration, greasy skin and hair, toning.

Digestive system: Dyspepsia, flatulence.

Nervous system: Convalescence, insomnia, nervous exhaustion and stress-related conditions.

OTHER USES: Extensively used as a fragrance component in soaps, detergents, cosmetics and perfumes, especially colognes (sometimes used to replace neroli). Employed as a flavour component in many foods, especially confectionery, as well as alcoholic and soft drinks.... petitgrain

Pine, Dwarf

Pinus mugo var. pumilio

FAMILY: Pinaceae

SYNONYMS: P. mugo, P. montana, P. pumilio, mountain pine, Swiss mountain pine, pine needle (oil).

GENERAL DESCRIPTION: A pyramidal shrub or small tree up to 12 metres high with a black bark, stiff and twisted needles borne in clusters, and brown cones, initially of a bluish hue.

DISTRIBUTION: Native to the mountainous regions of central and southern Europe. The oil is mainly produced in Austria (Tirol), Yugoslavia, Denmark and Italy.

OTHER SPECIES: There are very many species of pine used to produce essential oil from their needles and wood or employed in the production of turpentine. NB: The so-called huon pine (Dacrydium franklinii), the essential oil of which is also a skin irritant, belongs to a different family, the Podcarpaceae. For further details see Scotch pine and the Botanical Classification section.

HERBAL/FOLK TRADITION: A preparation made from the needles has been used internally for bladder, kidney and rheumatic complaints, as a liniment for rheumatism and muscular pain, and as an inhalant for bronchitis, catarrh, colds, etc.

ACTIONS: Analgesic, antimicrobial, antiseptic, antitussive, antiviral, balsamic, diuretic, expectorant, rubefacient.

EXTRACTION: Essential oil by steam distillation from the needles and twigs.

CHARACTERISTICS: A water-white liquid with a very pleasant, balsamic-sweet, spicy-woody scent of good tenacity. This is the favoured pine fragrance for perfumery use due to its unique delicate odour, which blends well with cedarwood, lavandin, rosemary, sage, cananga, labdanum, juniper and other coniferous oils.

PRINCIPAL CONSTITUENTS: Mainly monoterpene hydrocarbons; limonene, pinenes, phellandrene, dipentene, camphene, myrcene and bornyl acetate among others. The unusual scent is believed to be due to its aldehyde content.

SAFETY DATA: Dermal irritant, common sensitizing agent; otherwise non-toxic. It is best avoided therapeutically due to irritant hazards.

AROMATHERAPY/HOME: USE None.

OTHER USES: Used as a fragrance and flavour component in pharmaceutical preparations for coughs and colds, nasal congestion and externally in analgesic ointments and liniments. Extensively employed in soaps, bath preparations, toiletries, cosmetics and perfumes, especially ‘leather’ and ‘woody’ type fragrances. It is also used in most major food categories, alcoholic and soft drinks.... pine, dwarf

Pine, Longleaf

Pinus palustris

FAMILY: Pinaceae

SYNONYMS: Longleaf yellow pine, southern yellow pine, pitch pine, pine (oil).

GENERAL DESCRIPTION: A tall evergreen tree with long needles and a straight trunk, grown extensively for its timber. It exudes a natural oleoresin from the trunk, which provides the largest source for the production of turpentine in America – see also entry on turpentine.

DISTRIBUTION: Native to south eastern USA, where the oil is largely produced.

OTHER SPECIES: There are numerous other species of pine all over the world which are used to produce pine oil, as well as pine needle and turpentine oil – see Botanical Classification section.

HERBAL/FOLK TRADITION: Pine sawdust has been used for centuries as a highly esteemed household remedy for a variety of ailments. ‘It is a grand, gentle, although powerful external antiseptic remedy, applied as a poultice in rheumatism when localised, hard cancerous tumours, tuberculosis in the knee or ankle joints, disease of the bone, in short, all sluggish morbid deposits ... I have used it behind the head for failing sight, down the spine for general debility, on the loins for lumbago, etc. all with the best results.’.

ACTIONS: Analgesic (mild), antirheumatic, antiseptic, bactericidal, expectorant, insecticidal, stimulant.

EXTRACTION: The crude oil is obtained by steam distillation from the sawdust and wood chips from the heartwood and roots of the tree (wastage from the timber mills), and then submitted to fractional distillation under atmospheric pressure to produce pine essential oil.

CHARACTERISTICS: A water-white or pale yellow liquid with a sweet-balsamic, pinewood scent. It blends well with rosemary, pine needle, cedarwood, citronella, rosewood, ho leaf and oakmoss.

PRINCIPAL CONSTITUENTS: Terpineol, estragole, fenchone, fenchyl alcohol and borneol, among others.

SAFETY DATA: Non-toxic; non-irritant (except in concentration); possible sensitization in some individuals.

AROMATHERAPY/HOME: USE

Circulation muscles and joints: Arthritis, debility, lumbago, muscular aches and pains, poor circulation, rheumatism, stiffness, etc.

Respiratory system: Asthma, bronchitis, catarrh, sinusitis.

OTHER USES: Used extensively in medicine, particularly in veterinary antiseptic sprays, disinfectants, detergents and insecticides (as a solvent carrier). Employed as a fragrance component in soaps, toiletries, bath products and perfumes. Also used in paint manufacture although it is increasingly being replaced by synthetic ‘pine oil’.... pine, longleaf

Pine, Scotch

Pinus sylvestris

FAMILY: Pinaceae

SYNONYMS: Forest pine, Scots pine, Norway pine, pine needle (oil).

GENERAL DESCRIPTION: A tall evergreen tree, up to 40 metres high with a flat crown. It has a reddish-brown, deeply fissured bark, long stiff needles which grow in pairs, and pointed brown cones.

DISTRIBUTION: Native to Eurasia; cultivated in the eastern USA, Europe, Russia, the Baltic States and Scandinavia, especially Finland.

OTHER SPECIES: Like the fir tree, there are numerous species of pine which yield an essential oil from their heartwood as well as from their twigs and needles and are also used to produce turpentine. The oil from the needles of the Scotch pine is one of the most useful and safest therapeutically. Other species which produce pine needle oil include the eastern white pine (P. strobus) from the eastern USA and Canada, the dwarf pine (P. mugo var. pumilio) grown in central and southern Europe, and the black pine (P. nigra) from Austria and Yugoslavia.

Many varieties, such as the longleaf pine (Pinus palustris), are used to produce turpentine. In addition, the oil commonly known as Siberian pine needle oil is actually from the Siberian fir (Abies sibirica). See also dwarf pine and the Botanical Classification section.

HERBAL/FOLK TRADITION: The young macerated shoots are added to the bath for nervous exhaustion, circulatory disorders, slow, healing wounds, arthritis, rheumatism and skin disorders. It was used by the American Indians to prevent scurvy, and to stuff mattresses to repel lice and fleas.

As an inhalation it helps relieve bronchial catarrh, asthma, blocked sinuses, etc. The pine kernels are said to be excellent restoratives for consumptives, and after long illness.

ACTIONS: Antimicrobial, antineuralgic, antirheumatic, antiscorbutic, antiseptic (pulmonary, urinary, hepatic), antiviral, bactericidal, balsamic, cholagogue, choleretic, deodorant, diuretic, expectorant, hypertensive, insecticidal, restorative, rubefacient, stimulant (adrenal cortex, circulatory, nervous), vermifuge.

EXTRACTION: 1. Essential oil by dry distillation of the needles. 2. Gum turpentine is produced by steam distillation from the oleoresin: see entry on turpentine. (An inferior essential oil is also produced by dry distillation from the wood chippings, etc.)

CHARACTERISTICS: 1. Pine needle oil is a colourless or pale yellow mobile liquid with a strong, dry-balsamic, turpentine-like aroma. It blends well with cedarwood, rosemary, tea tree, sage, lavender, juniper, lemon, niaouli, eucalyptus and marjoram. 2. See entry on turpentine.

PRINCIPAL CONSTITUENTS: 50–90 per cent monoterpene hydrocarbons: pinenes, carene, dipentene, limonene, terpinenes, myrcene, ocimene, camphene, sabinene; also bornyl acetate, cineol, citral, chamazulene, among others.

SAFETY DATA: Non-toxic, non-irritant (except in concentration), possible sensitization. Avoid in allergic skin conditions.

AROMATHERAPY/HOME: USE

Skin care: Cuts, lice, excessive perspiration, scabies, sores.

Circulation muscles and joints: Arthritis, gout, muscular aches and pains, poor circulation, rheumatism.

Respiratory system: Asthma, bronchitis, catarrh, coughs, sinusitis, sore throat.

Genito-urinary system: Cystitis, urinary infection.

Immune system: Colds, ’flu.

Nervous system: Fatigue, nervous exhaustion and stress-related conditions, neuralgia.

OTHER USES: Used as a fragrance component in soaps, detergents, cosmetics, toiletries (especially bath products) and, to a limited extent, perfumes. Employed as a flavour ingredient in major food products, alcoholic and soft drinks.... pine, scotch

Plai

Zingiber cassumunar

FAMILY: Zingiberaceae

SYNONYMS: Z. montanum, Z. cassumunar ‘Roxburgh’, Z. purpureum ‘Roscoe’, cassumunar ginger.

GENERAL DESCRIPTION: The root of this tropical perennial plant is tuberous, with long fleshy fibres and jointed appendages, much like ginger but slightly larger. The fresh rhizome, which is yellow inside, has a cool, green, camphoraceous, spicy-warm scent. The stem is made of green leaf sheathes which are grass-like with brownish-purple pointed shoots bearing pale yellow flowers.

DISTRIBUTION: Native to Thailand, Indonesia and India: it is now commonly found throughout Asia. Since plai is an important medicinal plant in Thailand, there are many regions where plai is cultivated and there are now at least three native varieties or sub-species found in Thailand.

OTHER SPECIES: There are several sub-species (and essential oil chemotypes) of plai depending on the location of the plant from which it has been extracted. Essential oil produced from rhizomes grown in the north-west region is the most typical from Thailand and contains almost as much terpinen-4-ol as tea tree oil. Terpinen-4-ol has been well researched, and is to known to activate white blood cells: it also has significant antibacterial, antiviral and antifungal properties. Oil produced from the central region contains more sabinene. Zingiber cassumunar is a close relative of ginger and galangal, both of which are used to produce essential oils.

HERBAL/FOLK TRADITION: Zingiber cassumunar is widely used in folklore remedies as a single plant or as component of herbal recipes in Thailand and many Asian countries for the treatments of conditions, such as inflammation, sprains and strains, rheumatism and muscular pain. Although it is derived from the same plant family as ginger (Zingiber officinale), it does not possess the classic warming effect common to ginger. Instead, plai has a cooling action on inflamed areas, making it an excellent choice for treating injuries, post-operative pain and all types of muscular and joint pain such as torn muscles and ligaments as well as conditions such as arthritis and rheumatism. For this reason, plai has long been regarded by Thai massage therapists as one of the most essential oils to have at their disposal. Although generally diluted with a carrier oil, it can be applied directly to the skin when treating areas of severe pain or inflammation that are close to the surface of the skin. It is reported to ease pain for up to 16–20 hours – it is even used by Thai boxers for pain relief!

Used in skin care, the oil exhibits good antioxidant properties and is used in Thai culture to treat stretch marks and scars; also to heal wounds. Plai herbal compound is used traditionally in the form of a poultice and decoction for the treatment of a range of digestive disorders including colic, constipation, diarrhoea, flatulence, nausea heartburn. Zingiber cassumunar is also a traditional Thai remedy for respiratory conditions, including asthma, catarrh, colds and coughs, fever and influenza.

ACTIONS: Analgesic, antioxidant, antibacterial, antimicrobial, antihistamine, antineuralgic, antifungal, anti-inflammatory, antiseptic, antispasmodic, antitoxic, antiviral, carminative, digestive, diuretic, febrifugal, laxative, rubefacient, rejuvenating, stimulant, tonic, vermifuge.

EXTRACTION: Steam distilled from the fresh rhizome (roots) of the Plai plant (Zingiber cassumunar).

CHARACTERISTICS: The oil is a pale amber colour with a fresh, herbaceous, spicy-green scent and a resinous, slightly floral undertone. It will blends well with black pepper, bergamot, ginger, grapefruit, lemongrass, lime, jasmine, lavender, neroli, petitgrain, rosemary, sandalwood and tea tree.

PRINCIPAL CONSTITUENTS: The main active chemical constituents of the oil are terpinen-4-ol (up to 49 per cent) sabinene (up to 45 per cent), DMPBD (up to per cent), g-terpinene and a-terpinene – depending on the source of the oil.

SAFETY DATA: Non-toxic, non-irritating and non-sensitizing. Best to check for any possible sensitization due to variants in chemo-types available.

AROMATHERAPY/HOME: USE

Skin care: Acne, cuts, stretch marks, scars, wounds.

Circulation muscles and joints: All types of aches and pains caused by inflammation, including arthritis and rheumatism, cramp, gout, joint problems, muscle spasm, sprains and strains, torn muscles and ligaments as well as post-operative pain.

Digestive system: Cramps, colic, constipation, diarrhea, flatulence, indigestion, heartburn.

Respiratory system: Asthma, catarrh, chronic colds, bronchitis, congestion, fever, flu, sinusitis.

Genito-urinary system: Menstrual cramps.

Immune system: Stimulates the immune system and boosts vitality.

Nervous system: Anxiety, nervous tension, stress.

OTHER USES: The fresh rhizome or powdered root is much used in traditional Thai cuisine. The oil is used in the pharmaceutical industry, for example, in mosquito repellant formulations.... plai




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