see tonic pupil. [W. J. Adie (1886–1935), British physician]
A condition (described originally by Dr Argyll Robertson) in which the pupils contract when the eyes converge on a near object, but fail to contract when a bright light falls on the eye. It is found in several diseases, especially in locomotor ataxia and neurosyphilis, an advanced manifestation of SYPHILIS.... argyll robertson pupil
(Holmes-Adie syndrome) an abnormality of the pupils of the eyes, often affecting only one eye. The affected pupil is dilated and reacts slowly to light; the response on convergence *accommodation of the eyes is also slow (see tonic pupil). Tendon reflexes may be absent. The condition is almost entirely restricted to women. [W. J. Adie; Sir G. M. Holmes (1876–1965), British neurologist]... adie’s syndrome
(light reflex) the reflex change in the size of the pupil according to the amount of light entering the eye. Bright light reaching the retina stimulates nerves of the *parasympathetic nervous system, which cause the pupil to contract. In dim light the pupil opens, due to stimulation of the *sympathetic nervous system. See also iris.... pupillary reflex
(Adie’s pupil) a pupil that is dilated as a result of damage to the nerves supplying the ciliary muscle and iris. It reacts poorly to light but may constrict better for near vision, with slow redilation on refixation at a distance. The tonic pupil is sensitive to dilute 0.1% pilocarpine drops, which cause marked constriction but have little effect on a normal pupil. The tonic pupil may become miotic (see miosis) over time.... tonic pupil
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