Migrai ne Health Dictionary

Migrai Ne: From 1 Different Sources


A periodic condition with localised headaches, frequently associated with vomiting and sensory disturbances
Health Source: Medicinal Plants Glossary
Author: Health Dictionary

Nephritis

Inflation of the kidneys... nephritis

Neuralgia

A painful affection of the nerves due to functional disturbances or neuritis... neuralgia

Neurasthenia

Nervous debility... neurasthenia

Neoplasm

New or abnormal uncontrolled growth.... neoplasm

Acoustic Neuroma

A slow-growing, benign tumour in the auditory canal arising from the Schwann cells of the acoustic cranial nerve. The neuroma, which accounts for about 7 per cent of all tumours inside the CRANIUM, may cause facial numbness, hearing loss, unsteady balance, headache, and TINNITUS. It can usually be removed surgically, sometimes with microsurgical techniques that preserve the facial nerve.... acoustic neuroma

Anorexia Nervosa

See under EATING DISORDERS.... anorexia nervosa

Central Nervous System

A collective term for the brain, spinal cord, their nerves, and the sensory end organs. More broadly, this can even include the neurotransmitting hormones instigated by the CNS that control the chemical nervous system, the endocrine glands.... central nervous system

Necrosis

Death of tissue or cells, either from infection or the loss of normal circulation and autotoxicity.... necrosis

Nephropathy

Disease of the kidneys... nephropathy

Nervous System

This extensive, complex and ?nely tuned network of billions of specialised cells called neurones (see NEURON(E)) is responsible for maintaining the body’s contacts with and responses to the outside world. The network also provides internal communication links – in concert with HORMONES, the body’s chemical messengers – between the body’s diverse organs and tissues, and, importantly, the BRAIN stores relevant information as memory. Each neurone has a ?lamentous process of varying length called an AXON along which passes messages in the form of electrochemically generated impulses. Axons are bundled together to form nerves (see NERVE).

The nervous system can be likened to a computer. The central processing unit – which receives, processes and stores information and initiates instructions for bodily activities – is called the central nervous system: this is made up of the brain and SPINAL CORD. The peripheral nervous system – synonymous with the cables that transmit information to and from a computer’s processing unit – has two parts: sensory and motor. The former collects information from the body’s many sense organs. These respond to touch, temperature, pain, position, smells, sounds and visual images and the information is signalled to the brain via the sensory nerves. When information has been processed centrally, the brain and spinal cord send instructions for action via motor nerves to the ‘voluntary’ muscles controlling movements and speech, to the ‘involuntary’ muscles that operate the internal organs such as the heart and intestines, and to the various glands, including the sweat glands in the skin. (Details of the 12 pairs of cranial nerves and the 31 pairs of nerves emanating from the spinal cord are given in respective texts on brain and spinal cord.)

Functional divisions of nervous system As well as the nervous system’s anatomical divisions, the system is divided functionally, into autonomic and somatic parts. The autonomic nervous system, which is split into sympathetic and parasympathetic divisions, deals with the automatic or unconscious control of internal bodily activities such as heartbeat, muscular status of blood vessels, digestion and glandular functions. The somatic system is responsible for the skeletal (voluntary) muscles (see MUSCLE) which carry out intended movements initiated by the brain – for example, the activation of limbs, tongue, vocal cords (speech), anal muscles (defaecation), urethral sphincters (urination) or vaginal muscles (childbirth). In addition, many survival responses – the most powerfully instinctive animal drives, which range from avoiding danger and pain to shivering when cold or sweating when hot – are initiated unconsciously and automatically by the nervous system using the appropriate neural pathways to achieve the particular survival reaction required.

The complex functions of the nervous system include the ability to experience emotions, such as excitement and pleasure, anxiety and frustration, and to undertake intellectual activities. For these experiences an individual can utilise many built-in neurological programmes and he or she can enhance performance through learning – a vital human function that depends on MEMORY, a three stage-process in the brain of registration, storage and recall. The various anatomical and functional divisions of the nervous system that have been unravelled as science has strived to explain how it works may seem confusing. In practical terms, the nervous system works mainly by using automatic or relex reactions (see REFLEX ACTION) to various stimuli (described above), supplemented by voluntary actions triggered by the activity of the conscious (higher) areas of the brain. Some higher functions crucial to human activity – for example, visual perception, thought, memory and speech – are complex and subtle, and the mechanisms are not yet fully understood. But all these complex activities rest on the foundation of relatively simple electrochemical transmissions of impulses through the massive network of billions of specialised cells, the neurones.... nervous system

Neuritis

Nerve inflammation, usually with an abnormal amount of pain, and often part of a degenerative process.... neuritis

Trigeminal Neuralgia

Facial neuralgia or tic doulourex. This is pain of the gasserian ganglion or one or more branches of the trigeminal nerves. It is felt as pain along the side or top of the head, the scalp and around the eyes...a “skin headache”...and sometimes accompanied by facial muscle cramps. It is usually initiated by trigger points, with blood sugar irregularities and substance sensitivities often lowering their threshold of irritation.... trigeminal neuralgia

Auditory Nerve

See VESTIBULOCOCHLEAR NERVE.... auditory nerve

Autonomic Nervous System

Part of the nervous system which regulates the bodily functions that are not under conscious control: these include the heartbeat, intestinal movements, salivation, sweating, etc. The autonomic nervous system consists of two main divisions – the SYMPATHETIC NERVOUS SYSTEM and the PARASYMPATHETIC NERVOUS SYSTEM. The smooth muscles, heart and most glands are connected to nerve ?bres from both systems and their proper functioning depends on the balance between these two. (See also NERVES; NERVOUS SYSTEM.)... autonomic nervous system

Cranial Nerves

Cranial nerves are those arising from the BRAIN.... cranial nerves

Facial Nerve

The seventh cranial nerve (arising from the BRAIN), supplying the muscles of expression in the face, being purely a motor nerve. It enters the face immediately below the ear after splitting up into several branches. (See BELL’S PALSY.)... facial nerve

Hypoglossal Nerve

The 12th cranial nerve, which supplies the muscles of the tongue, together with some others lying near it. This nerve is responsible for movements required for swallowing and talking. (See also NERVOUS SYSTEM.)... hypoglossal nerve

Haemolytic Disease Of The Newborn

A potentially serious disease of the newborn, characterised by haemolytic ANAEMIA (excessive destruction of red blood cells) and JAUNDICE. If severe, it may be obvious before birth because the baby becomes very oedematous (see OEDEMA) and develops heart failure – so-called hydrops fetalis. It may ?rst present on the ?rst day of life as jaundice and anaemia. The disease is due to blood-group incompatibility between the mother and baby, the commoneset being rhesus incompatibility (see BLOOD GROUPS). In this condition a rhesus-negative mother has been previously sensitised to produce rhesus antibodies, either by the delivery of a rhesus-positive baby, a miscarriage or a mismatched blood transfusion. These antibodies cross over into the fetal circulation and attack red blood cells which cause HAEMOLYSIS.

Treatment In severely affected fetuses, a fetal blood transfusion may be required and/or the baby may be delivered early for further treatment. Mild cases may need observation only, or the reduction of jaundice by phototherapy alone (treatment with light, involving the use of sunlight, non-visible ULTRAVIOLET light, visible blue light, or LASER).

Whatever the case, the infant’s serum BILIRUBIN – the bilirubin present in the blood – and its HAEMOGLOBIN concentration are plotted regularly so that treatment can be given before levels likely to cause brain damage occur. Safe bilirubin concentrations depend on the maturity and age of the baby, so reference charts are used.

High bilirubin concentrations may be treated with phototherapy; extra ?uid is given to prevent dehydration and to improve bilirubin excretion by shortening the gut transit time. Severe jaundice and anaemia may require exchange TRANSFUSION by removing the baby’s blood (usually 10 millilitres at a time) and replacing it with rhesus-negative fresh bank blood. Haemolytic disease of the newborn secondary to rhesus incompatibility has become less common since the introduction of anti-D (Rho) immunoglobulin. This antibody should be given to all rhesus-negative women at any risk of a fetomaternal transfusion, to prevent them from mounting an antibody response. Anti-D is given routinely to rhesus-negative mothers after the birth of a rhesus-positive baby, but doctors should also give it after threatened abortions, antepartum haemorrhages, miscarriages, and terminations of pregnancy.

Occasionally haemolytic disease is caused by ABO incompatibility or that of rarer blood groups.... haemolytic disease of the newborn

Nebula

The term applied to a slight opacity on the cornea (see EYE) producing a haze in the ?eld of vision, and also to any oily preparation to be sprayed from a nebuliser – an apparatus for splitting up a ?uid into ?ne droplets.... nebula

Neck

The connecting tissues between the scolex and strobila of a tapeworm. This part is unsegmented.... neck

Necropsy

A traditional term for an autopsy or POSTMORTEM EXAMINATION.... necropsy

Nephrosis

Degeneration of the kidney, with high discharge of albumin in the urine. Anaemia, dropsy and protein loss.

Causes: recurrent attacks of nephritis, bacterial toxins, environmental poisons, mineral drugs (mercury etc).

Treatment. Specific hospital treatment essential, (dialysis etc). Simple phytomedicines may bring a measure of relief as supportives to conventional medicine.

Teas. Barley water, Buchu, Clivers, Cornsilk, Couchgrass, Goldenrod, Parsley, Plantain, Wild Carrot. Decoctions. Broom tops, Dandelion root, Marshmallow root, Hydrangea root, Parsley root.

Powders. Alfalfa 45; Bearberry 15; Buchu 10; Couchgrass 15; Wild Carrot 15. Dose: 500-750mg (2-3 00 capsules or one-third to half a teaspoon) thrice or more daily.

Tinctures. Echinacea 2 (to enhance powers of resistance). Parsley root 2; Ginseng 1; Ginger quarter. Dose: 1-2 teaspoons in water thrice or more daily.

Restharrow herb. For weak kidneys and bladder. (R.F Weiss MD. Book: Herbal Medicine, Beaconsfleld Publishers)

Diet. High protein, salt-free, herb teas. Spring water in abundance.

Supplements. Vitamin A, B-complex, B2, C, E. Calcium, Iron, Magnesium.

Supportives. Hot abdominal packs. Castor oil packs. Sweat packs. Induce sweating with aid of diaphoretics.

Subsequent treatment by or in liaison with a qualified medical practitioner. ... nephrosis

Neomycin

Neomycin is one of the AMINOGLYCOSIDES, derived from Streptomyces fradiae. It has a wide antibacterial spectrum, being e?ective against the majority of gram-negative (see GRAM’S STAIN) bacilli. Its use is limited by the fact that it is liable to cause deafness and kidney damage. Its main use is for application to the skin – either in solution or as an ointment – for the treatment of infection; it is also given by mouth for the treatment of certain forms of ENTERITIS due to E. coli.... neomycin

Neoplasia

The presence of abnormal cells forming a growth or tumor, unable to perform their normal functions, and replacing healthy cells.... neoplasia

Neostigmine

An ANTICHOLINESTERASE drug which enhances neuromuscular transmission – the passage of chemical messages between nerve and muscle cells – in voluntary and involuntary muscles in patients with the disorder MYASTHENIA GRAVIS. Its e?ect lasts for about four hours. A disadvantage is that it has a marked cholinergic action – affecting heart rhythm, causing excessive salivation and tear secretion, constricting the BRONCHIOLES and stimulating the gastrointestinal tract.... neostigmine

Nephrectomy

The operation for removal of the kidney. (See KIDNEYS, DISEASES OF.)... nephrectomy

Nephroblastoma

Nephroblastoma, or Wilm’s tumour, is the commonest kidney tumour in infancy (see also KIDNEYS, DISEASES OF – Tumours of the kidney). It is a malignant tumour, which occurs in around 1 per 10,000 live births. The survival rate with modern treatment (removal of the kidney followed by radiotherapy and chemotherapy) is now around 80 per cent.... nephroblastoma

Nephrology

The branch of medicine concerned with the study and management of kidney disease. A specialist in these diseases is called a nephrologist.... nephrology

Nephron

Each kidney comprises over a million of these microscopic units which regulate and control the formation of URINE. A tuft of capillaries invaginates the Bowmans capsule, which is the blind-ending tube (GLOMERULUS) of each nephron. Plasma is ?ltered out of blood and through the Bowmans capsule into the renal tubule. As the ?ltrate passes along the tubule, most of the water and electrolytes are reabsorbed. The composition is regulated with the retention or addition of certain molecules (e.g. urea, drugs, etc.). The tubules eventually empty the ?ltrate, which by now is urine, into the renal pelvis from where it ?ows down the ureters into the bladder. (See KIDNEYS.)... nephron

Nephrostomy

Nephrostomy is the operation of making an opening into the kidney (see KIDNEYS) to drain it.... nephrostomy

Nephrotic Syndrome

Nephrotic syndrome is one of PROTEINURIA, hypo-albuminaemia and gross OEDEMA. The primary cause is the leak of albumin (see ALBUMINS) through the GLOMERULUS. When this exceeds the liver’s ability to synthesise albumin, the plasma level falls and oedema results. The nephrotic syndrome is commonly the result of primary renal glomerular disease (see KIDNEYS, DISEASES OF – Glomerulonephritis). It may also be a result of metabolic diseases such as diabetic glomerular sclerosis and AMYLOIDOSIS. It may be the result of systemic autoimmune diseases such as SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) and POLYARTERITIS NODOSA. It may complicate malignant diseases such as MYELOMATOSIS and Hodgkin’s disease (see LYMPHOMA). It is sometimes caused by nephrotoxins such as gold or mercury and certain drugs, and it may be the result of certain infections such as MALARIA and CROHN’S DISEASE.... nephrotic syndrome

Nerve Block

See ANAESTHESIA – Local anaesthetics.... nerve block

Nervous Breakdown

A non-medical description of a variety of emotional crises ranging from an outburst of hysterical behaviour to a major neurotic illness that may have a lasting e?ect on an individual’s life. Sometimes the term is used to describe an overt psychotic illness – for example, SCHIZOPHRENIA (see also MENTAL ILLNESS; NEUROSIS).... nervous breakdown

Nerve

A nerve is a bundle of conductory ?bres called axons (see AXON) that emanate from neurones (see NEURON(E)) – the basic anatomical and functional units of the NERVOUS SYSTEM. Nerves make up the central nervous system (BRAIN and SPINAL CORD) and connect that system to all parts of the body, transmitting information from sensory organs via the peripheral nerves to the centre and returning instructions for action to the relevant muscles and glands.

Nerves vary in size from the large pencil-sized sciatic nerve in the back of the thigh muscles to the single, hair-sized ?bres distributed to the skin. A nerve, such as the sciatic, possesses a strong, outer ?brous sheath, called the epineurium, within which lie bundles of nerve-?bres, divided from one another by partitions of ?brous tissue, in which run blood vessels that nourish the nerve. Each of these bundles is surrounded by its own sheath, known as the perineurium, and within the bundle ?ne partitions of ?brous tissue, known as endoneurium, divide up the bundle into groups of ?bres. The ?nest subdivisions of the nerves are the ?bres, and these are of two kinds: medullated and non-medullated ?bres. (See NEURON(E) and NERVOUS SYSTEM for more details on structure and functions of neurons and nerves.)... nerve

Nettle-rash

See URTICARIA.... nettle-rash

Nettle

Urtica and Laportea species

Description: These plants grow several feet high. They have small, inconspicuous flowers. Fine, hairlike bristles cover the stems, leafstalks, and undersides of leaves. The bristles cause a stinging sensation when they touch the skin.

Habitat and Distribution: Nettles prefer moist areas along streams or at the margins of forests. They are found throughout North America, Central America, the Caribbean, and northern Europe.

Edible Parts: Young shoots and leaves are edible. Boiling the plant for 10 to 15 minutes destroys the stinging element of the bristles. This plant is very nutritious.

Other Uses: Mature stems have a fibrous layer that you can divide into individual fibers and use to weave string or twine.... nettle

Neuroblastoma

A malignant growth comprising embryonic nerve cells. It may start in any part of the AUTONOMIC NERVOUS SYSTEM. The medulla of the adrenal gland (see under ENDOCRINE GLANDS) is a common site; secondary growths develop in other tissues. Neuroblastomas are the most common extracranial solid tumour of childhood. The incidence is around eight cases per one million children. Treatment is by surgery followed by radiotherapy and CYTOTOXIC drugs. About 30 per cent of sufferers survive for at least ?ve years after treatment.... neuroblastoma

Neurology

The branch of medical practice and science which is concerned with the study of the NERVOUS SYSTEM and its disorders. Specialists in neurology – neurologists – examine a patient’s nerves, sensory and motor functions and re?exes. They use modern imaging techniques

– for example, CT scanning (see COMPUTED TOMOGRAPHY) and MRI – to aid diagnosis. Until relatively recently, many neurological conditions could be treated only with palliative methods. Now there is much improved understanding of the nervous system and its disorders, with closer liaison between psychiatrists (see PSYCHIATRY) and neurologists.... neurology

Neuroma

Neuroma means a TUMOUR connected with a NERVE – such tumours being generally composed of ?brous tissue, and of a painful nature.... neuroma

Neuropathy

A disease affecting nerves (see NERVE). It may affect a single nerve (mononeuropathy) or be a generalised disorder (polyneuropathy). Symptoms will depend on whether motor, sensory, or autonomic nerves are affected. Trauma or entrapment of a nerve is a common cause of mononeuropathy, pressure or stretching of a nerve occurring in various situations. Complete recovery in 4–6 weeks is usual. Common causes of polyneuropathy include DIABETES MELLITUS, vitamin B de?ciency (often alcohol-associated) and some viral infections. Genetic and toxic neuropathies are also seen.... neuropathy

Neurosurgery

Surgery performed on some part of the NERVOUS SYSTEM, whether brain, spinal cord or nerves. Disorders treated by neurosurgeons include damage to the brain, spinal cord and nerves as a result of injury; tumours in the CENTRAL NERVOUS SYSTEM; abnormalities of blood vessels in or supplying blood to the brain – for example, ANEURYSM; brain abscess; bleeding inside the skull; and certain birth defects such as HYDROCEPHALUS and SPINA BIFIDA.... neurosurgery

Neurosis

A general term applied to mental or emotional disturbance in which, as opposed to PSYCHOSIS, there is no serious disturbance in the perception or understanding of external reality. However, the boundaries between neurosis and psychosis are not always clearly de?ned. Neuroses are usually classi?ed into anxiety neuroses, depressive neuroses, phobias (see PHOBIA), HYPOCHONDRIASIS, HYSTERIA and obsessional neuroses.

Anxiety neurosis, or anxiety state, constitutes the most common form of neurosis; fortunately it is also among the most responsive to treatment. Once the neurosis develops, sufferers are in a state of persistent anxiety and worry, ‘tensed up’, always fatigued and unable to sleep at night. In addition, there are often physical complaints – for example, palpitations, sweating, apparent discomfort on swallowing (‘globus’), and headache.

Obsessional neuroses are much less common and constitute only about 5 per cent of all neuroses. Like other neuroses, they usually develop in early adult life. (See MENTAL ILLNESS.)... neurosis

Neurotransmitter

A chemical substance which transmits the action of a NERVE to a cell (see CELLS). It is released from nerve-endings and transmits the impulse across synapses (see SYNAPSE) to other nerves. In the central nervous system the substances acting as neurotransmitters include ACETYLCHOLINE, NORADRENALINE, DOPAMINE and SEROTONIN. The main transmitter in the peripheral system is acetylcholine, while for the sympathetic system it is noradrenaline. In recent years a new group of neurotransmitters called neuropeptides has been identi?ed, comprising large protein molecules. One of the best-known is that of endorphins, which the brain uses to control pain. (See also NEURON(E); NERVOUS SYSTEM; PAIN.)... neurotransmitter

Neutrophil

A type of leucocyte or white blood cell (see LEUCOCYTES; BLOOD).... neutrophil

Optic Nerve

See EYE.... optic nerve

Optic Neuritis

In?ammation of the optic nerve (see EYE) which may result in sudden loss of part of a person’s vision. It is usually accompanied by pain and tenderness on touch. The cause is uncertain, although in some cases it may be a prcursor of MULTIPLE SCLEROSIS (MS): CORTICOSTEROIDS may help by improving the loss of visual acuity, but seems not to check the long-term in?ammatory activity.... optic neuritis

Peripheral Nervous System

See NERVOUS SYSTEM.... peripheral nervous system

Pins And Needles

A form of PARAESTHESIA, or disturbed sensation, such as may occur, for example, in NEURITIS or POLYNEURITIS.... pins and needles

Radial Nerve

This NERVE arises from the BRACHIAL plexus in the axilla. At ?rst descending posteriorly and then anteriorly, it ends just above the elbow by dividing into the super?cial radial and interosseous nerves. It supplies motor function to the muscles which extend the arm, wrist, and some ?ngers, and supplies sensation to parts of the posterior and lateral aspects of the arm, forearm and hand.... radial nerve

Retrobulbar Neuritis

In?ammation of the optic nerve behind (rather than within) the EYE. It usually occurs in young adults and presents with a rapid deterioration in vision over a few hours. Colour vision is also impaired. Usually vision recovers over a few weeks, but colour vision may be permanently lost. It can be associated with certain viral illnesses and with MULTIPLE SCLEROSIS (MS). (See also EYE, DISORDERS OF.)... retrobulbar neuritis

Sacral Nerves

These are five pairs of CNS nerves that exit through the sacral foramen and sacral hiatus, and bring information in and out of the spinal cord. Much of their function relates to the sciatic nerve, and they bring information in from the skin sensory zones (dermatomes) of the heel, back of the legs, buttocks, and the pelvic floor.... sacral nerves

Sympathetic Nervous System

Part of the AUTONOMIC NERVOUS SYSTEM. It consists of scattered collections of grey matter known as ganglia, united by an irregular network of nerve-?bres; those portions where the ganglia are placed most closely and where the network of ?bres is especially dense being known as plexuses. The chief part of the sympathetic system consists of two ganglionated cords that run through the neck, chest, and abdomen, lying close in front of the spine. In conjunction with the other part of the autonomic nervous system – the parasympathetic – this part controls many of the body’s involuntary activities involving glands, organs and other tissues. (For further details, see NERVOUS SYSTEM.)... sympathetic nervous system

Trigeminal Nerve

The ?fth cranial nerve (arising from the BRAIN). It consists of three divisions: (1) the ophthalmic nerve, which is purely sensory in function, being distributed mainly over the forehead and front part of the scalp; (2) the maxillary nerve, which is also sensory and distributed to the skin of the cheek, the mucous membrane of the mouth and throat, and the upper teeth; and (3) the mandibular nerve, which is the nerve of sensation to the lower part of the face, the tongue and the lower teeth, as well as being the motor nerve to the muscles concerned in chewing. The trigeminal nerve is of special interest, owing to its liability to NEURALGIA – TRIGEMINAL NEURALGIA, or tic douloureux as it is also known, being the most painful form known.... trigeminal nerve

Trochlear Nerve

The fourth cranial nerve (arising from the BRAIN), which acts upon the superior oblique muscle of the EYE.... trochlear nerve

Ulnar Nerve

A major NERVE in the arm, it runs from the brachial plexus to the hand. The nerve controls the muscles that move the ?ngers and thumb and conveys sensation from the ?fth and part of the fourth and from the adjacent palm. Muscle weakness and numbness in the areas supplied by the nerve is usually caused by pressure from an abnormal outgrowth from the epicondyle at the bottom of the humerus (upper-arm bone).... ulnar nerve

Vagus Nerve

Also called the pneumogastric nerve, this is the tenth cranial nerve, with many fibers leading to parasympathetic ganglia in internal organs, and can be considered the presynapse starter for the upper parts of the parasympathetic functions.... vagus nerve

Vestibulocochlear Nerve

The eighth cranial nerve. It consists of two sets of ?bres, which constitute two separate nerves. One is known as the vestibular nerve, which connects the semicircular canals and inner ear to the BRAIN and conveys information on posture and movement of the body; it is the nerve of equilibration or balance. The other is known as the cochlear nerve, which links the COCHLEA (organ that responds to sounds) with the brain and is the nerve of hearing. Disturbance of the former causes giddiness (VERTIGO), whilst disturbance of the latter causes DEAFNESS.... vestibulocochlear nerve

Abducent Nerve

This is the sixth nerve rising from the brain and controls the external rectus muscle of the EYE, which turns the eye outwards. It is particularly liable to be paralysed in diseases of the nervous system, thus leading to an inward squint.... abducent nerve

Cardiac Neurosis

Obsessional fear about the state of the heart. It tends to occur after a heart attack and may result in the patient’s experiencing the symptoms of another attack.... cardiac neurosis

False Negative

A negative test result for a condition that is, in fact, present.... false negative

Gram-positive/negative

Gram’s Method is a staining procedure that separates bacteria into those that stain (positive) and those that don’t (negative). Gram-positive bugs cause such lovely things as scarlet fever, tetanus, and anthrax, while some of the gram negs can give you cholera, plague, and the clap. This is significant to the microbiologist and the pathologist; otherwise I wouldn’t worry. Still, knowing the specifics (toss in anaerobes and aerobes as well), you can impress real medical professionals with your knowledge of the secret, arcane language of medicine.... gram-positive/negative

Lacrimal Nerve

A branch of the ophthalmic nerve supplying the lacrimal gland and conjunctiva of the EYE.... lacrimal nerve

Medical Negligence

Under the strict legal de?nition, negligence must involve proving a clearly established duty of care which has been breached in a way that has resulted in injury or harm to the recipient of care. There does not need to be any malicious intention. Whether or not a particular injury can be attributed to medical negligence, or must simply be accepted as a reasonable risk of the particular treatment, depends upon an assessment of whether the doctor has fallen below the standard expected of practitioners in the particular specialty. A defence to such a claim is that a respected body of practitioners would have acted in the same way (even though the majority might not) and in doing so would have acted logically.... medical negligence

Motor Neurone Disease (mnd)

A group of disorders of unknown origin. Certain cells in the neurological system’s MOTOR nerves degenerate and die. Upper and lower motor neurones may be affected but sensory cells retain their normal functions. Three types of MND are identi?ed: amyotrophic lateral sclerosis (AML – 50 per cent of patients); progressive muscular atrophy (25 per cent), in which the prognosis is better than for AML; and bulbar palsy (25 per cent). Men are affected more than women, and the disorder affects about seven people in every 100,000. Those affected develop progressive weakness and wasting of their muscles. The diagnosis is con?rmed with various tests including the measurement of electrical activity in muscles, electromyography, muscle BIOPSY, blood tests and X-ray examination of the spine. There is no medical treatment: patients need physical and psychological support with aids to help them overcome disabilities. The Motor Neurone Disease Association provides excellent advice and help for sufferers and their relatives. (See APPENDIX 2: ADDRESSES: SOURCES OF INFORMATION, ADVICE, SUPPORT AND SELF-HELP.)... motor neurone disease (mnd)

Needle-stick Injury

Accidental perforation of the skin by an injection needle, commonly of the hand or ?nger and usually by a nurse or doctor administering a therapeutic injection. The term also refers to accidental injuries from injection needles discarded by drug abusers. Dangerous infections such as viral HEPATITIS or HIV may be acquired from needle-stick injuries, and there are strict procedures about the disposal of used syringes and needles in medical settings.... needle-stick injury

Needling

An operation performed in the treatment of cataracts (see under EYE, DISORDERS OF), in which the anterior lens capsule of the EYE is torn open with a needle, allowing the aqueous ?uid to dissolve the opaque soft lens matter, which is gradually washed away into the bloodstream. This ‘extra-capsular extraction’ may need to be repeated several times before all the opaque lens matter disperses. Although a relatively simple procedure, it is unsuitable for patients over the age of 35 (when the nucleus of the lens becomes increasingly hard), and CRYOSURGERY and LASER therapy have become the preferred methods of treatment.

Needling is also used for certain minor dermatological procedures, such as removal of small facial cysts and scabies mites.... needling

Neem

Azadirachta indica

Meliaceae

San: Nimbah, Prabhadrah Hin,

Ben: Nim, Nim Mal: Aryaveppu

Tel: Vepa Ori: Nimba

Tam: Vembu, Veppu Pun: Bakam,Bukhain

Guj: Limba

Kan: Bevu Mar: Limbu

Importance: Neem or margose tree, also known as Indian lilac is a highly exploited medicinal plant of Indian origin, widely grown and cultivated throughout India. Every part of the tree, namely root, bark, wood, twig, leaf, flower, fruit, seed, kernel and oil has been in use from time immemorial in the Ayurvedic and Unani systems of medicine. Nimbarishta, nimbadi churna and nimbharidra khand are well known preparations. It is valuable as an antiseptic, used in the treatment of small pox. Small twigs are used as tooth brushes and as a prophylactic for mouth and teeth complaints. Extract from the leaves are useful for sores, eczema and skin diseases. Boiled and smashed leaves serve as excellent antiseptic. Decoction of leaves is used for purifying blood. Neem oil is used in soaps, toothpaste and as a hair tonic to kill lice. Seed is used in snake bite. The fruits and leaves being renewable, provide sustainable returns. Different parts of the fruit are separated into components and each one produces derivatives of varying chemical nature and utility. Neem derivatives are now used in agriculture, public health, human and veterinary medicines, toiletries, cosmetics and livestock production. Applications as pesticides, allied agrochemicals, plant nutrients and adjuvants for improving nitrogen use efficiency are of much importance. Neem kernel suspension (1%) is a house hold insecticide. Pesticide formulations containing azadirachtin are now commercially available in India, USA, Canada, Australia and Germany. Neem cake is rich in N, P, K, Ca and S. Neem Meliacins like epinimbin and nimbidin are commercially exploited for the preparation of slow and extended release of nutrients including nitrification inhibitors (Eg. Nimin). Extracts of neem seed oil and bark check the activity of male reproductive cells and prevents sperm production. Neem seed oil is more effective than the bark for birth control. Neem based commercial products are also available for diabetes treatment (Nimbola, JK-22), contraceptive effect (Sensal, Nim-76) and mosquito/ insect repelling (Srivastava, 1989; Tewari, 1992; Parmer and Katkar, 1993; Pushpangadan et al, 1993; Mariappan, 1995).

Distribution: Neem is a native of the Siwalik deccan parts of South India. It grows wild in the dry forests of Andra Pradesh, Tamil Nadu and Karnataka. It has spread to Pakistan, Bangladesh , Sri Lanka, Malaysia, Indonesia, Thailand, Middle East Sudan and Niger. It is now grown in Australia, Africa, Fiji, Mauritious, Central and South America, the Carribeans, Puerto Rico and Haiti. The largest known plantation of nearly 50,000 trees is at Arafat plains en route to Mecca in Saudi Arabia for providing shade to Haj pilgrims (Ahmed, 1988).

Botany: The genus Azadirachta of family Meliaceae comprises two species: A. indica A. Juss syn. Melia azadirachta Linn. and A. excelsa (Jack) Jacobs syn. A. integrifolia Mers., the latter being found in Philippines, Sumatra, Malaya, Borneo and New Guinea. Neem is a hardy medium to large, mostly evergreen tree attaining 20m height and 2.5m girth. It has a short bole with wide spreading branches and glabrous twigs forming a round to oval crown. The bark is thick, dark-gray with numerous longitudinal furrows and transverse cracks. Leaves are imparipinnately compound, alternate, exstipulate and 20-38cm long. Inflorescence is long, slender, axillary or terminal panicle. Flowers are white or pale yellow, small, bisexual, pentamerous and bracteate. Stamens 10; filaments unite to form a moniliform tube. Gynoecium is tricarpellary and syncarpous, ovary superior, trilocular. Each carpel bears two collateral ovules on parietal placentation. Fruit is one seeded drupe with woody endocarp, greenish yellow when ripe. Seed ellipsoid, cotyledons thick fleshy and oily. Neem has chromosome number 2n = 28. Neem trees tend to become deciduous for a brief period in dry ecology. Ecotypes, exhibiting morphological variation in root growth, leaf size, contents, bole length , canopy, inflorescence, fruit bearing, seed size, shape and quality exist in natural populations.

Agrotechnology: Neem grows in tropical arid regions with high temperatures, altitudes between 50m and 1000m, as little rainfall as 130mm/yr and long stretches of drought. Well drained sunny hill places are ideal. It grows on most kinds of soils including dry, stony, shallow, nutrient deficient soils with scanty vegetation, moderately saline and alkali soils, black cotton, compact clays and laterite crusts. However, silty flats, clayey depressions and land prone to inundation are not conducive for its growth (Chaturvedi, 1993). Soil pH of 5.0 to 10.0 is ideal. It brings surface soil to neutral pH by its leaf litter. It has extensive and deeply penetrating root system capable of extracting moisture and nutrients even from highly leached poor sandy soils.

Neem propagates easily by seed without any pretreatment, though it can be regenerated by vegetative means like root and shoot cuttings. Seeds are collected from June to August. These remain viable for 3-5 weeks only which necessitates sowing within this short time. Seeds may be depulped and soaked in water for 6 hours before sowing. Seeds are sown on nursery beds at 15x5cm spacing, covered with rotten straw and irrigated. Germination takes 15-30 days. Seedlings can be transplanted after two months of growth onwards either to polybags or to mainfield. Neem can be grown along with agricultural crops like groundnut, bean, millets, sorghum and wheat. It is also suitable for planting in roadsides, for afforestation of wastelands and under agroforestry system. For field planting, pits of size 50-75 cm cube are dug 5-6m apart, filled with top soil and well rotten manure, formed into a heap, and seedling is planted at the centre of the heap. FYM is applied at 10-20 kg/plant every year. Chemical fertilizers are not generally applied. Irrigation and weeding are required during the first year for quick establishment.

More than 38 insect pests are reported on Neem which may become serious at times. The important ones are seed and flower insect (Scirtothrips dorsalis Hood), defoliators (Boarmia variegata Moore and Eurema sp.), sap suckers (Helopeltes antonii Signoret and Pulvinaria maxima Green) , root feeders (Hototrichia consanguinea Blanchard), mealy bug (Pseudococus gilbertensis), scale insect (Parlatoria orientalis) and a leaf webber (Loboschiza Koenigiana)(Beeson, 1941, Bhasin et al, 1958, Parmar, 1995). They can be controlled by the application of 0.01-0.02% monocrotophos or dimethoate. No serious diseases are reported in Neem. Flowering starts after 5 years. In India flowering is during January-May and fruits mature from May-August. The leaves are shed during February- March and a full grown tree produces about 350 kg dry leaves and 40-50 kg berries per annum. Fresh fruits give 60% dry fruits which yield 10% kernel which contains 45% fixed oil, on an average. After 10 years of growth the wood can be cut and used as timber.

Properties and Activity: Dry Neem leaves contain carbohydrates 47-51%, crude protein 14-19%, crude fiber 11-24%, fat 2-7%, ash 7-9%, Ca 0.8-2.5% and P 0.1-0.2%. Leaves also contain the flavanoid quercetin, nimbosterol (-sitosterol), kaempferol and myricetin. Seed and oil contains desacetylnimbin, azadirachtin (C35H44O16), nimbidol, meliantriol ,tannic acid, S and amino acids. Neem cake contain the highest sulphur content of 1.07% among all the oil cakes. Trunk bark contains nimbin 0.04%, nimbinin 0.001%, nimbidin 0.4%, nimbosterol 0.03%, essential oil 0.02%, tannins 6.0 %, margosine and desacetylnimbin (Atal and Kapur, 1982; Thakur et al 1989).

Neem bark is bitter, astringent, acrid, refrigerant, depurative, antiperiodic, vulnerary, demulcent, insecticidal, liver tonic, expectorant and anthelmintic. Leaves are bitter, astringent, acrid, depurative, antiseptic, ophthalmic, anthelmintic, alexeteric, appetizer, insecticidal, demulcent and refrigerant. Seed and oil are bitter, acrid, thermogenic, purgative, emollient, anodyne, anthelmintic depurative, vulnerary, uterine stimulant, urinary astringent, pesticidal and antimicrobial (Warrier et al, 1993).... neem

Negativism

Negativism means a morbid tendency in a person to do the opposite of what he or she is desired or directed to do. It is especially characteristic of those suffering from SCHIZOPHRENIA, but is not uncommon in non-psychotic persons.... negativism

Accessory Nerve

The 11th cranial nerve. Unlike the other cranial nerves, most of the accessory nerve originates from the spinal cord. The small part of the nerve that originates from the brain supplies many muscles of the palate, pharynx (throat), and larynx (voice box). Damage to this part of the nerve may cause difficulty in speaking and swallowing. The spinal part of the nerve supplies large muscles of the neck and back, notably the sternomastoid and trapezius. Damage to the spinal fibres of the nerve paralyses these muscles.... accessory nerve

Acoustic Nerve

The part of the vestibulocochlear nerve (the 8th cranial nerve) that is concerned with hearing. It is also known as the auditory nerve.... acoustic nerve

Avascular Necrosis

The death of cells in body tissue caused by damage to blood vessels supplying the area.

aversion therapy An outdated form of behaviour therapy in which unpleasant stimuli, such as electric shocks, are administered at the same time as an unwanted behaviour in an attempt to alter behavioural patterns.... avascular necrosis

Negligence

See MEDICAL NEGLIGENCE.... negligence

Nematode

A roundworm. (See ASCARIASIS.)... nematode

Nematodes

Unsegmented worms having a gut and a body cavity (pseudocoel). Are round in transverse section. Many species are parasitic.... nematodes

Neonatology

The branch of PAEDIATRICS responsible for the medical care of newborn babies. Problems may be short term – for example, those linked to prematurity – or life-long such as CEREBRAL PALSY. After the ?rst few weeks of life, paediatricians take over the responsibility for any specialist medical care required, with general practitioners looking after the infants’ primary-care needs.... neonatology

Nephralgia

Pain in the kidney... nephralgia

Nephrolithiasis

A condition in which CALCULI are present in the kidney.... nephrolithiasis

Nephropexy

Surgical ?xation (to the 12th rib and posterior abdominal wall) of a mobile kidney; this prevents the kidney from descending in the abdomen when the affected person stands up.... nephropexy

Nephroptosis

The condition in which a kidney (see KIDNEYS) is mobile or ‘?oating’ instead of being ?xed to the back of the abdominal cavity.... nephroptosis

Nephroscope

An endoscopic instrument for examining the inside of the kidney (see KIDNEYS). It is normally passed into the renal pelvis of the organ via a route from the surface of the skin. Instruments can be passed through the nephroscope under direct vision to remove CALCULI (stones) or break them up using ULTRASOUND.... nephroscope

Nephrotomy

Nephrotomy means the operation of cutting into the kidney (see KIDNEYS), in search of CALCULI or for other reasons.... nephrotomy

Nerve Cell

See NEURON(E).... nerve cell

Neural Tube

The structure in the EMBRYO from which the BRAIN and SPINAL CORD develop.... neural tube

Neural Tube Defects

Congenital abnormalities resulting from the failure of the NEURAL TUBE to form normally. The resulting conditions include SPINA BIFIDA, MENINGOCELE and defects in the bones of the SKULL.... neural tube defects

Neurectomy

An operation in which part of a NERVE is excised: for example, for the relief of NEURALGIA.... neurectomy

Neurilemma

The thin membranous covering which surrounds every nerve-?bre. (See NERVE.)... neurilemma

Neurogenic

Sensations or conditions derived solely from the nervous system... neurogenic

Neuroglia

The ?ne web of tissue and branching cells which supports the nerve-?bres and cells of the nervous system. (See NERVE.)... neuroglia

Neuromuscular Junction

The area where a motor NERVE ends close to the MUSCLE membrane so can initiate muscle contraction. The motor-nerve ending is separated from the motor end plate by the synaptic cleft which is only 50–70 nm wide. When a nerve impulse arrives at the motor-nerve ending, molecules of ACETYLCHOLINE are released which cross the synaptic cleft and attach to receptors on the motor end plate. This initiates depolarisation of the muscle which in turn initiates the process of contraction. Acetylcholinesterase (an ENZYME) rapidly breaks down the molecules of acetylcholine, thus ending their action and freeing the receptor in preparation for the next impulse.... neuromuscular junction

Neuropathic Bladder

A URINARY BLADDER with complete or partial loss of sensation. As there is no sensation of fullness, the individual either develops complete retention of URINE, or the bladder empties automatically – usually every few hours. The condition predisposes affected individuals to urinary-tract infections and back pressure on the KIDNEYS, leading to renal failure. It may be caused by spinal injury, SPINA BIFIDA or any disorder which produces NEUROPATHY.... neuropathic bladder

Neuropathology

The branch of PATHOLOGY that covers the reasons for and consequences of disorders of the NERVOUS SYSTEM (see also NEUROLOGY).... neuropathology

Neurotoxin

A chemical substance that harms nervous tissue, causing symptoms of numbness or weakness of the body part supplied by the damaged NERVE. The venom of some snakes contains neurotoxic substances, and bacteria may produce neurotoxins: examples are those that cause DIPHTHERIA and TETANUS. Arsenic and lead are examples of inorganic neurotoxins.... neurotoxin

Neutropenia

A reduction in the number of neutrophil LEUCOCYTES per cubic millimetre of circulating blood to a ?gure below that found in health. There is still some disagreement over the precise limits of normality, but a count of fewer than 1,500 per mm3 would be generally accepted as constituting neutropenia. Several infective diseases are characterised by neutropenia, including typhoid fever (see ENTERIC FEVER), INFLUENZA and MEASLES. It may also be induced by certain drugs, including chloramphenicol, the sulphonamides and chlorpromazine.... neutropenia

Phrenic Nerve

The NERVE which chie?y supplies the DIAPHRAGM. A phrenic nerve arises on each side of the SPINAL CORD from the third, fourth and ?fth cervical spinal nerves; both follow a long course down the neck, and through the chest to the diaphragm. They play a key part in RESPIRATION through control of the diaphragm. Injury to one nerve paralyses one half of the diaphragm. Occasionally the phrenic nerve may be surgically crushed as part of the treatment to repair a HIATUS HERNIA or, rarely, to stop intractable hiccups.... phrenic nerve

Pudendal Nerve

The nerve that operates the lowest muscles of the ?oor of the PELVIS and also the anal SPHINCTER muscle. It may be damaged in childbirth, resulting in INCONTINENCE.... pudendal nerve

Parasympathetic Nervous System

That part of the AUTONOMIC NERVOUS SYSTEM which is connected with the BRAIN and SPINAL CORD through certain nerve centres in the midbrain, medulla, and lower end of the cord. The nerves from these centres are carried in the third, seventh, ninth and tenth cranial nerves and the second, third and fourth sacral nerves. The action of the parasympathetic system is usually antagonistic to that of the sympathetic system. Thus it inhibits the action of the HEART and augments the action of the INTESTINE; whereas the sympathetic augments the action of the heart and inhibits that of the intestine. (See diagram of sympathetic and parasympathetic nervous systems under NERVOUS SYSTEM.)... parasympathetic nervous system

Wry-neck

A condition in which the head is twisted to one side. It may be caused by the contraction of a scar, such as that resulting from a burn or by paralysis of some of the muscles; as a result of injury at birth; or trauma to the area later in life. Treatment is by an orthopaedic collar, heat or ULTRASOUND, or PHYSIOTHERAPY. Sometimes a local injection of BOTULISM toxin will produce temporary relief. Rarely, surgery is necessary. (See also MUSCLES, DISORDERS OF – Cramp; SPASMODIC TORTICOLLIS.)... wry-neck

Cervical Intraepithelial Neoplasia

Also known as , abnormalities in the cells of the cervix which may become cancerous.

The grading system is used to distinguish levels of change in the surface cells of the cervix in biopsy samples taken during colposcopy, a procedure usually performed following an abnormal cervical smear test.

Grades 1–3 broadly correspond to mild to severe cervical dysplasia in cells obtained from a smear.... cervical intraepithelial neoplasia

Entrapment Neuropathy

A condition, such as carpal tunnel syndrome, in which local pressure on a nerve causes muscle pain, numbness, and weakness in the area that the nerve supplies.... entrapment neuropathy

Femoral Nerve

One of the main nerves of the leg. The nerve fibres making up the femoral nerve emerge from the lower spine and run down into the thigh, where they branch to supply the skin and quadriceps muscles.

Damage to the femoral nerve (which impairs the ability to straighten the knee) is usually caused by a slipped disc in the lumbar region of the spine (see disc prolapse). Damage may also result from a backward dislocation of the hip or a neuropathy.... femoral nerve

Glossopharyngeal Nerve

The ninth cranial nerve.

This nerve performs both sensory and motor functions.

It conveys sensations, especially taste, from the back of the tongue, regulates secretion of saliva by the parotid gland, and controls movement of the throat muscles.... glossopharyngeal nerve

Nebulizer

An aerosol device used to administer a drug in the form of a fine mist for inhalation through a face mask or mouthpiece.

Nebulizers are used to administer bronchodilator drugs, especially in the emergency treatment of asthma.... nebulizer

Motor Neuron Disease

A group of disorders in which there is degeneration of the nerves in the central nervous system that control muscular activity. This causes weakness and wasting of the muscles. The cause is unknown.

The most common type of motor neuron disease is amyotrophic lateral sclerosis ( or Lou Gehrig’s disease). It usually affects people over the age of 50 and is more common in men. Some cases run in families. Usually, symptoms start with weakness in the hands and arms or legs, and muscle wasting. There may be irregular muscle contractions, and muscle cramps or stiffness. All four extremities are soon affected.

Progressive muscular atrophy and progressive bulbar palsy both start with patterns of muscle weakness different from but usually develop into.There are 2 types of motor neuron disease that first appear in childhood or adolescence. In most cases, these conditions are inherited. Werdnig–Hoffman disease affects infants at birth or soon afterwards. In almost all cases, progressive muscle weakness leads to death within several years. Chronic spinal muscular atrophy begins in childhood or adolescence, causing progressive weakness but not always serious disability.

There are no specific tests for motor neuron disease. Diagnosis is based on careful clinical examination by a neurologist. Tests including EMG, muscle biopsy, blood tests, myelography, CT scanning, or MRI may be performed.

The disease typically goes on to affect the muscles involved in breathing and swallowing, leading to death within 2–4 years. However, about 10 per cent of sufferers survive for 10 years.

Nerve degeneration cannot be slowed down, but physiotherapy and the use of various aids may help to reduce disability. The drug riluzole is used to extend life (or the time until mechanical ventilation is required).... motor neuron disease

Necrotizing Fasciitis

A rare, serious infection of tissues beneath the skin by a type of streptococcal bacterium.

Necrotizing fasciitis is most likely to occur as a complication following surgery.

The initial symptoms are inflammation and blistering of the skin.

The infection spreads very rapidly, and the bacteria release enzymes and toxins that can cause extensive destruction of deeper tissues and damage internal organs.

Urgent treatment with antibiotic drugs and removal of all infected tissue are essential.

The infection is life-threatening.... necrotizing fasciitis

Nelson’s Syndrome

A rare disorder of the endocrine system that causes increased skin pigmentation. Nelson’s syndrome results from enlargement of the pituitary gland, which can follow removal of the adrenal glands (a treatment for Cushing’s syndrome).

Nelson’s syndrome is treated by hypophysectomy (removal or destruction of the pituitary gland).... nelson’s syndrome

Neologism

The act of making up new words that have a special meaning for the inventor. The term also refers to the invented words themselves. Persistent neologism can be a feature of speech in people with schizophrenia.... neologism

Neonate

A newly born infant, under the age of 1 month (see newborn).... neonate

Nephrocalcinosis

Deposits of calcium within the tissue of 1 or both kidneys. Nephrocalcinosis is not the same as kidney stones (see calculus, urinary tract), in which calcium particles develop inside the drainage channels of the kidney. Nephrocalcinosis may occur in any condition in which the level of calcium in the blood is raised. It may also occur as a result of taking excessive amounts of certain antacid drugs or vitamin D. Treatment is of the underlying cause to prevent further calcification.... nephrocalcinosis

Nephrolithotomy

The surgical removal of a calculus (stone) from the kidney.

Nephrolithotomy may be performed through an abdominal incision, or via a puncture incision in the back. Large

calculi may need to be broken up before removal. Other methods of removal are pyelolithotomy and lithotripsy.... nephrolithotomy

Nephrosclerosis

Hardening of the arterioles and arteries of the kidney.... nephrosclerosis

Neurapraxia

A type of nerve injury in which the outward structure of a nerve appears intact, but some of the conducting fibres have been damaged or have degenerated and thus do not transmit signals normally.... neurapraxia

Neurodermatitis

An itchy, eczema-like skin condition caused by repeated

scratching. (See also lichen simplex.)... neurodermatitis

Neuropsychiatry

The branch of medicine dealing with the relationship between psychiatric symptoms and neurological disorder.

This may include the effects of head injury and alcohol on the brain, or disorders such as brain tumours, infections, inherited illnesses, and disorders causing brain damage in childhood.... neuropsychiatry

Neurosyphilis

Infection of the brain or spinal cord that occurs in untreated syphilis many years after initial infection.

Damage to the spinal cord due to neurosyphilis may cause tabes dorsalis, characterized by poor coordination of leg movements, urinary incontinence, and pains in the abdomen and limbs. Damage to the brain may cause dementia, muscle weakness, and, in rare cases, total paralysis of the limbs.... neurosyphilis

Oculomotor Nerve

The 3rd cranial nerve, controlling most of the muscles that move the eye. The oculomotor nerve also supplies the muscle that constricts the pupil, that which raises the upper eyelid, and the ciliary muscle, which focuses the eye. The nerve may be damaged due to a fracture to the base of the skull or a tumour. Symptoms include ptosis, squint, dilation of the pupil, inability to focus the eye, double vision, and slight protrusion of the eyeball. (See also trochlear nerve; abducent nerve.)... oculomotor nerve

Neurofibromatosis

An uncommon disorder that is inherited. Also called von Recklinghausen’s disease, neurofibromatosis is characterized by numerous neurofibromas (soft, fibrous swellings, varying significantly in size), which grow from nerves, and by café au lait spots (pale, coffee-coloured patches) on the skin, usually on the trunk and pelvis. If neurofibromas occur in the central nervous system, they may cause epilepsy and other complications. Neurofibromatosis can lead to bone deformities. Rarely, neurofibromas become cancerous.

Surgical removal of neurofibromas is necessary only if there are complications.

Anyone with this disorder, and parents of an affected child, should seek genetic counselling if planning a pregnancy.... neurofibromatosis

Neuron

The term used to describe a nerve cell. A typical neuron consists of a cell body, several branching projections called dendrites, and a filamentous projection called an axon (also known as a nerve fibre). An axon branches at its end to form terminals through which electrical signals are transmitted to target cells. Most axons are coated with a layered insulating myelin sheath, which speeds the transmission of the signals. The myelin sheath is punctuated along its length by gaps called nodes of Ranvier, which help this process. Because the myelin sheath is nonconductive, ion exchange (depolarization) only occurs at a node, and signals leap from node to node along the length of the axon.

The nervous system contains billions of neurons, of which there are 3 main types: sensory neurons, which carry signals from sense receptors into the central nervous system (CNS); motor neurons, which carry signals from the CNS to muscles or glands; and interneurons, which form all the complex electrical circuitry within the CNS itself.

When a neuron transmits (“fires”) an electrical impulse, a chemical called a neurotransmitter is released from the axon terminals at synapses (junctions with other neurons). This neurotransmitter may make a muscle cell contract, cause an endocrine gland to release a hormone, or affect an adjacent neuron.

Different stimuli excite different types of neurons to fire. Sensory neurons, for example, may be excited by physical stimuli, such as cold or pressure. The activity of most neurons is controlled by the effects of neurotransmitters released from adjacent neurons. Certain neurotransmitters generate a sudden change in the balance of electrical potential inside and outside the cell (an “action potential”), which occurs at one point on the cell’s membrane and flows at high speed along it. Others stabilize neuronal membranes, preventing an action potential. Thus, the firing pattern of a neuron depends on the balance of excitatory and inhibitory influences acting on it.

If the cell body of a neuron is damaged or degenerates, the cell dies and is never replaced. A baby starts life with the maximum number of neurons, which decreases continuously thereafter.... neuron

Olfactory Nerve

The first cranial nerve, which conveys sensations of smell as nerve impulses from the nose to the brain. Each of the 2 olfactory nerves has receptors in the mucous membrane lining the nasal cavity. These receptors detect smells and send signals along nerve fibres, which pass through tiny holes in the roof of the nasal cavity and combine to form the olfactory bulbs. From here, nerve fibres come together to form the olfactory nerve, leading to the olfactory centre in the brain. Sense of smell may be lost or impaired due to damage to the olfactory nerves, usually as a result of head injury.... olfactory nerve

Ophthalmia Neonatorum

A type of eye inflammation and discharge (ophthalmitis) that occurs in newborn infants, usually as a result of infection with gonorrhoea or chlamydia at birth.

The infection is treated with antibiotic drugs.... ophthalmia neonatorum

Sciatic Nerve

The main nerve in each leg and the largest nerve in the body.The sciatic nerves are formed from nerve roots in the spinal cord.... sciatic nerve

Spinal Nerves

A set of 31 pairs of nerves that connect to the spinal cord. Spinal nerves emerge in 2 rows from either side of the spinal cord and leave the spine through gaps between adjacent vertebrae. The nerves then branch out to supply all parts of the trunk, arms, and legs with sensory and motor nerve fibres.

Disc prolapse may lead to pressure on a spinal nerve, causing pain. Injury to a nerve may lead to loss of sensation or movement in the area supplied by the nerve. (See also nerve injury; neuropathy.)... spinal nerves

Transcutaneous Electrical Nerve Stimulation

See TENS.... transcutaneous electrical nerve stimulation

Anaphalis Neelgerriana

DC.

Family: Compositae; Asteraceae.

Habitat: The Nilgiri Hills at 2,1002,500 m.

Ayurvedic: Raktaskandana.

Folk: Kaatplaaster (Nilgiri hills).

Action: Antiseptic. Fresh leaves are bruised and applied to wounds and cuts as plaster.

An acyl flavonoid glycoside, ana- phaloside, along with isoquercitrin and astragalin, has been isolated from the flowers of a related sp. Anaphalis contorta, used as an antibacterial and styptic.... anaphalis neelgerriana

Community Health Information Network (chin)

An integrated collection of computer and telecommunication capabilities that permit multiple providers, payers, employers and related health care entities within a geographic area to share and communicate client, clinical and payment information.... community health information network (chin)

Euphorbia Neriifolia

Auct. Non Linn.

Synonym: E. ligularia Roxb.

Family: Euphorbiaceae.

Habitat: Grown as a field and boundary fence and as curious on rockeries in gardens.

English: Holy Milk Hedge, Dog's Tongue.

Ayurvedic: Snuhi, Samant-dugdhaa, Sehunda, Singhtunda, Snuk, Gudaa, Sudhaa, Vajra, Vajjri, Vajjradram, Thuuhar.

Siddha/Tamil: Ielaikkali, Perumbu- kalli.

Action: Latex—purgative, diuretic, antiasthmatic, expectorant, rube- facient. Used in ascites, polyuria, anasarca, chlorosis, tympanitis; externally on warts, cutaneous eruptions, scabies, unhealthy ulcers.

A succus compounded of equal parts of the juice and simple syrup is said to be used for giving relief in asthma.

The triterpenoids, euphol, 24-meth- ylenecycloartenol, euphorbol hexa- cosonate, glut-5 (10)-en-1-one, glut-5- en-3 beta-yet-acetate, taraxerol, friede- lan-3 alpha-ol and -3 beta-ol have been reported from the plant.... euphorbia neriifolia

Fat Necrosis

In injury to, or in?ammation of, the PANCREAS, the fat-splitting enzyme in it may escape into the abdominal cavity, causing death of fat-containing cells.... fat necrosis

Ha-neul

(Korean) Of the sky... ha-neul

Geranium Nepalense

Sweet.

Synonym: G. affine W. & A.

Family: Geraniaceae.

Habitat: Temperate Himalayas, Kashmir, Khasi Hills and the Nilgiris.

English: Nepal Geranium, Nepalese Crane's Bill.

Ayurvedic: Bhanda, Bhandaa.

Folk: Ratanjot (var.), Roel (Kashmir).

Action: Astringent, styptic, used in renal diseases, diarrhoea, internal and external bleeding. Also used topically for ulcers and haemorrhoids.

The plant gave geraniin, kaempferol- 7-rhamnoside and kaempferitrin. The leaves gave tannins.

EtOH (50%) extract of the plant exhibited hypotensive activity.

A gastrointestinal-contracting cho- line-like substance has been isolated from var. thumbergii and is found useful for the treatment of gastrointestinal disorders such as gastroptosis.... geranium nepalense

Hedera Nepalensis

Koch.

Synonym: H. helix auct. non Linn. H. himalaica Tobler.

Family: Araliaceae.

Habitat: The Himalayas; from Kashmir to Bhutan at 1,5002,000 m and Assam at 1,3502,000 m.

English: Nepal Ivy.

Folk: Baandaa, Bandaa, Lablab.

Action: Leaves and berries— cathartic, diaphoretic, febrifuge, antispasmodic, expectorant. Used in whooping cough. Leaves— used in glandular enlargements. A decoction of the leaves is used topically to destroy lice in the hair. An infusion of berries is given in rheumatism. Gum— emmenagogue.

The inflorescences contain beta- amyrin, beta-sitosterol and its D-glu- coside, oleanolic acid, triterpene gly- cosides, nepalins. Nepalins 1,2 and 3 at 0.5, 0.25 and 0.125% respectively completely immobilize human sperm.

Plant extract exhibited antitumour activity in vivo and in vitro against Ehrich ascites.... hedera nepalensis

Idiopathic Facial Nerve Palsy

See BELL’S PALSY.... idiopathic facial nerve palsy

Integrated Delivery System / Integrated Services Network (isn)

A network of organizations, usually including hospitals and medical practitioner groups, that provides or arranges to provide a coordinated continuum of services to a defined population and is held both clinically and financially accountable for the outcomes in the populations served.... integrated delivery system / integrated services network (isn)

Iris Nepalensis

D. Don.

Family: Iridaceae.

Habitat: Temperate Himalaya and in Khasi Hills.

Ayurvedic: Paarseeka Vachaa.

Folk: Sosan, Shoti, Chalnundar, Chiluchi.

Action: Deobstruent (in bilious obstructions), diuretic, cathartic. Used in diseases of the liver.

The plant contains an isoflavone, irisolidone. Rhizomes contain iriso- lone and irigenin.... iris nepalensis

Neala

(Gaelic) Feminine form of Neal; a champion

Neale, Nealla, Neila, Neile, Neilla, Neille, Neely, Neelie, Nealina, Neilina, Neelle, Neela, Nealie, Neali, Nelia, Nelea, Niall, Niala, Nialla, Niela, Nielsine... neala

Nebraska

(Native American) From the flat water land; from the state of Nebraska... nebraska

Lindera Nessiana

Benth.

Family: Lauraceae.

Habitat: Temperate Himalayas from Nepal eastwards at 1,800-2,400 m, and in Assam.

Folk: Gandha-daaru (Bengal), Siltimur (Nepal).

Action: Carminative.

The plant is reported to yield sassafras, which is substituted for the true sassafras from Cinnamomum glan- duliferum Meissn.

The seeds yield a fatty oil (60.7%). It gave methyl esters : methyl laurate 75.2, methyl caprate 13.3, methyl oleate 5.4, methyl myristate 2.4, and methyl- palmitate 0.5%.... lindera nessiana

Nebulisers

A nebuliser makes an aerosol (see under INHALANTS) by blowing air or oxygen through a solution of a drug. Many inhaled drugs such as SALBUTAMOL, ipratropium and beclomethasone can be given in this way. It has the advantage over a metered dose inhaler (MDI) that no special e?ort is required to coordinate breathing, and a nebuliser allows a much greater volume of the drug to be delivered to where it is needed (the airways) compared with that of MDIs. The use of higher doses of bronchodilator drugs made possible by the nebuliser means that the risk of unwanted side-effects is also increased. Fortunately the safety pro?le of anti-asthmatic drugs such as salbutamol is extremely high and overdose is generally well-tolerated.... nebulisers

Necator Americanus

A hookworm, closely resembling but smaller than the Ancylostoma duodenale. (See ANCYLOSTOMIASIS.)... necator americanus

Nechama

(Hebrew) One who provides comfort

Nehama, Nehamah, Nachmanit, Nachuma, Nechamah, Nechamit... nechama

Neci

(Latin) A passionate woman; one who is fiery

Necia, Necie, Necee, Necy, Necey, Necea... neci

Necrotising Fasciitis

Also known as CELLULITIS. A potentially lethal infection caused by the gram-positive (see GRAM’S STAIN) bacterium Streptococcus pyogenes which has the property of producing dangerous exotoxins. The infection, which starts in the layer of FASCIA under the SKIN, may spread very rapidly, destroying tissue as it spreads. Urgent antibiotic treatment may check the infection, and surgery is sometimes required, but even with treatment patients may die (see STREPTOCOCCUS).... necrotising fasciitis

Neda

(Slavic) Born on a Sunday Nedda, Nedah, Nedi, Nedie, Neddi, Neddie, Nedaa... neda

Nediva

(Hebrew) A giving and noble woman

Nedivah, Nedeeva, Nedyva, Nedeevah, Nedyvah, Nedeava, Nedeavah... nediva

Nedra

(English) Woman of the underground

Nedrah, Neddra, Needra, Needrah... nedra

Neeharika

(Indian) Of the morning dew Neharika, Neeharyka, Neharyka... neeharika

Neeja

(Indian) Resembling a water lily Neejah, Nyja, Neerja, Neerjah, Nyrja, Neaja, Neajah, Nearja... neeja

Neelam

(Indian) As precious as a sapphire Nelam, Nylam, Nealam, Neylam... neelam

Neem Tea - An Indian Herbal Tea

Neem tea is a refreshing herbal tea, with origins in South Asia. Despite its bitter taste, it is often recommended as a beverage thanks to its many health benefits. Read this article to find out more about neem tea! About Neem Tea Neem tea is made from the leaves of the Neem tree. The tree can be found in India, Bangladesh and Pakistan. It is an evergreen tree which can grow up to twenty feet in just three years, and it starts bearing fruit after 3-5 years. However, during periods of severe drought, it may shed most or even all of its leaves. The green leaves are 20-40cm long, with medium to dark green leaflets about 3-8cm long; the terminal leaflet is usually missing. The tree’s flowers are small, white and fragrant, arranged axillary. The fruit has an olive-like form, with a thin skin and a yellow-white, fibrous and bittersweet pulp. How to prepare Neem Tea To brew a cup of neem tea, you have to follow a few simple steps. First, boil the necessary amount of water. Then, pour it over a cup with includes a few neem leaves. Let it steep for about 5 minutes. Lastly, remove the leaves and, if you think it is needed, flavor it with honey and/or lemon. You can make your own stack of neem leaves for neem tea. If you’ve got neem trees around, gather leaves and leave them to dry. You can use fresh neem leaves, as well. In both cases though, you have to wash the leaves well before you use them. Once you’ve got the leaves ready, whether dry or fresh, just follow the earlier-mentioned steps. You can also make a cup of neem tea by using powdered neem leaf. Neem Tea Benefits Neem leaves have many antibacterial and antiviral properties. Thanks to this, neem tea is full of health benefits. Indians chew on neem twigs to have a good oral hygiene. However, a cup of neem tea can also help you maintain a good oral hygiene. It is useful in treating bad breath and gum disease, and it fights against cavities. Neem tea is also useful in treating fungal infections, such as yeast infections, jock itch, thrush, and ringworm. Neem tea can help you treat both indigestion and constipation. It is also useful when it comes to reducing swelling of the stomach and intestinal tract, and it can be used to counter ulcers and gout. Neem tea, when combined with neem cream, has anti-viral uses. It can help speed up the healing time and pain associated with herpes simplex 1, herpes zoster and warts. Neem tea is also used in the treatment of malaria and other similar diseases. It helps purify and cleanse the blood, as well; therefore, it increases liver function. Other important benefits that are related to consumption of neem tea are: treating pneumonia, treating diabetes, treating hypertension and heart diseases. Also, neem tea doesn’t have to be used only as a beverage. Because of its anti-parasitic use, you can bathe in it. This way, the tea acts as an antiseptic, killing the parasites. Neem Tea Side Effects While we can say that neem tea has plenty of important health benefits, don’t forget that there are a few side effects, as well. First of all, neem oil can be incredibly toxic for infants. Even a small amount of neem oil can cause death. Check to see if the neem tea you drink has neem oil among its ingredients. Or, just to be on the safe side, don’t give infants neem tea to drink. You shouldn’t drink neem tea if you have a history of stomach, liver or kidney problems. Some of its active ingredients can cause you harm in this case. Although rare, neem tea can also lead to allergic reactions. Symptoms in this case include difficulty in breathing, rashes, itching, or swelling of the throat or mouth. If you get any of these, stop drinking neem teaand contact your doctor. Drinking neem tea is a big no if you’re trying to conceive, or you’re already pregnant. In the first case, neem tea can work as a contraceptive, therefore lessening the chances of you getting pregnant. In the second case, consumption of neem tea can lead to miscarriages. Also, don’t drink more than six cups of neem teaa day - or any other type of tea. It won’t do you well, despite its many health benefits. Some of the symptoms you might get are: headaches, dizziness, insomnia, irregular heartbeats, vomiting, diarrhea and loss of appetite. If you get any of these symptoms, reduce the amount of neem tea you drink. As a herbal tea, neem tea is definitely good for your health. Still, despite its many health benefits, there are a few side effects as well. Keep them both in mind when drinking neem tea.... neem tea - an indian herbal tea

Neema

(African) Born into prosperity Neemah, Neama, Neamah, Neyma, Neymah... neema

Neena

(Hindi) A woman who has beautiful

eyes

Neenah, Neanah, Neana, Neyna, Neynah... neena

Nefertiti

(Egyptian) A queenly woman Nefertari, Nefertyty, Nefertity, Nefertitie, Nefertitee, Nefertytie, Nefertitea... nefertiti

Nefopam Hydrochloride

A non-opioid analgesic drug (see ANALGESICS) of use in the relief of pain that fails to respond to other non-opioid analgesics. It causes little depression of respiration but side-effects may be a problem.... nefopam hydrochloride

Negeen

(Persian) As precious as a gem Negeene, Negyne, Negyn, Negine, Negean, Negeane... negeen

Nervous Bowel Syndrome

Frequent urging to stool due to nervous irritability or emotional distress.

Indicated: astringents, nerve relaxants.

Teas. Hops, Vervain, Chamomile, Cranesbill.

Tablets/capsules. Chamomile, Calamus, Wild Yam, Fenugreek.

Formula. Bayberry 2; Wild Yam 1; Valerian half. Dose: Liquid extracts: 1-2 teaspoons. Tinctures: 2-3 teaspoons. Powders: 750mg (three 00 capsules or half a teaspoon). Thrice daily.

Tincture. Black Catechu BHP (1983). 1:5 in 45 per cent alcohol. Dose 2.5 to 5ml in water, thrice daily. Fenulin. (Gerard House)

Diet. Slippery Elm gruel.

Supplements. Vitamins A, B6, C, Calcium, Dolomite. ... nervous bowel syndrome

Nervous Debility

Nerve weakness; loss of strength and power.

To strengthen nerves and generate vitality: Ginseng, Bee pollen, Oats, Ginkgo, Saw Palmetto, Damiana. Tea. Formula. Equal parts: Betony, Balm, Skullcap. One heaped teaspoon to each cup boiling water; infuse 5-15 minutes. 1 cup thrice daily.

Gentian. One teaspoon fine-cut root in cup cold water; infuse overnight. Strain; drink cold following morning.

Tablets/capsules: Damiana, Skullcap, Lady’s Slipper, Ginseng, Ginkgo.

Formula. Equal parts: Gentian, Oats. Gotu Kola. Dose: Liquid Extracts: 2 teaspoons. Tinctures: 3 teaspoons. Powders: 750mg (three 00 capsules or half a teaspoon). Thrice daily.

After surgical operation: St John’s Wort. Hawthorn. ... nervous debility

Nervous Exhaustion

See: EXHAUSTION. ... nervous exhaustion

Nervous Stomach

Stomach hypersensitivity, with absence of acidity or organic disturbance. Calamus, Cinnamon, Burnett Saxifrage, Lovage, Fumitory, Rosemary, Wormwood, Oats, Skullcap.

German Chamomile tea. ... nervous stomach

Nerve Tension

Nervous excitability, irritability, prone to over-reaction by anger or other destructive emotion.

Teas. Cowslip flowers, St John’s Wort flowers, Passion flower, Valerian, Hops, Lime flowers, Balm, Motherwort, Woodruff, Skullcap, Oats.

Formula, tea: equal parts, Balm, Motherwort, Passion flower. 1 heaped teaspoon to each cup boiling water; infuse 5-10 minutes. 1 cup thrice daily.

Tablets. Valerian. Pulsatilla. Natracalm. (English Grains) 500mg Passion flower tablets: 1 tablet thrice daily.

See: SEDATIVES. ... nerve tension

Nervous Shock

Non-medical term for nervous collapse. “All gone to pieces” syndrome following a period of abnormal stress or shock. Nervous breakdown. Psychiatric illness. Posttraumatic stress disorder.

Alternatives. Betony, Black Cohosh, Hops, Lady’s Slipper, Mistletoe, Oats, Skullcap, Valerian.

Tea. Formula. Equal parts: Skullcap, Mistletoe, Valerian. 1 heaped teaspoon to each cup water gently simmered 10 minutes. Dose: half-1 cup thrice daily.

Formula. Equal parts: Hops, Rosemary, Valerian. Dose: Liquid Extracts: 1 teaspoon. Tinctures: 2 teaspoons. Powders: 500mg (two 00 capsules or one-third teaspoon). Thrice daily.

Supplements. B-complex, B12, B6, E. Magnesium, Dolomite. Calcium. ... nervous shock

Nervousness In Young Women

With menstrual problems, menopausal women, ovarian pain, or weak nerves after childbrith.

Tea. Combine equal parts: Raspberry leaves, Skullcap, Motherwort. 1 heaped teaspoon to each cup boiling water; infuse 15 minutes. 1 cup freely.

Formula. Equal parts: Black Cohosh, Helonias, Valerian. Dose: Liquid Extracts: half a teaspoon. Tinctures: 1 teaspoon. Powders: 250mg thrice daily.

Supplements. B-complex. Vitamin C to aid iron absorption. ... nervousness in young women

Asthenia, Neurocirculatory

See cardiac neurosis.... asthenia, neurocirculatory

Neginoth

(Hebrew) An accomplished musician

Neginothe, Negynoth, Negynothe, Neginotha, Negynotha... neginoth

Neglect

The refusal or failure on the part of a person (or persons) in a caring role to fulfil a care-giving obligation, either consciously or unintentionally, which results in physical or emotional distress for an older person. See also “abuse”.... neglect

Negri Bodies

Inclusions found in the cytoplasm of brain neurons in rabies.... negri bodies

Neha

(Indian) One who loves and is loved Nehah, Nyha, Nyhah... neha

Nehama

(Hebrew) One who provides comfort Nehamah, Nehamma, Nehammah, Nehamia, Nehamea, Nehamiya

... nehama

Nehanda

(African) Our beautiful daughter has come to us

Nehandah, Nehandia, Nehandea, Nehandiya... nehanda

Nehara

(Hebrew) Born of the light Neharah, Neharra, Nehira, Nehirah, Nehura, Nehurah, Nehora, Nehorah, Nahara, Naharah... nehara

Nehelamite

(Hebrew) A dreamer Nehelamitte, Nehelamit, Nehelamyte, Nehelamytte, Nehelamyt... nehelamite

Nehushta

(Hebrew) Resembling copper Nehushtah... nehushta

Neighbourhood Health Centre

See “community health centre”.... neighbourhood health centre

Neisseriaceae

A family of bacteria of which three varieties cause disease. Neisseria meningitidis causes meningococcal MENINGITIS and SEPTICAEMIA. It is divided into three groups: A, B and C; group B accounts for most meningitis cases in the UK, mostly affecting children. Neisseria gonorrhoeae causes GONORRHOEA. The bacteria are gram-negative (see GRAM’S STAIN) cocci usually occurring in pairs. A third variety is Moraxella catarrhalis: this occurs in the nose and throat and sometimes causes ear infection and low-grade infection of the respiratory tract.... neisseriaceae

Neith

(Egyptian) In mythology, goddess of war and hunting

Neitha, Neytha, Neyth, Neit, Neita, Neitia, Neitea, Neithe, Neythe... neith

Nekana

(Spanish) Woman of sorrow Nekane, Nekania, Nekanea... nekana

Nekhbet

(Egyptian) In mythology, a goddess depicted as a vulture Nechbet, Nekbet, Nekhebit... nekhbet

Nelly

(English) Form of Helen, meaning “the shining light”

Nel, Nelida, Nell, Nella, Nellene, Nellie, Nellwen, Nellwin, Nelle, Nelley, Nelli, Nellee, Nellis, Nelma, Nellwinne, Nellwenne, Nellwyn, Nellwynne, Nelwina, Nelwena, Nellwina, Nellwena, Nelda, Nelleke... nelly

Nelsey

(English) Form of Kelsey, meaning “from the island of ships; of the ship’s victory” Nellsea, Nellseigh, Nellsey, Nellsie, Nelsea, Nelseigh, Nelsie, Nelsy, Nelsee, Nellsee, Nellsy, Nellsi... nelsey

Nelumbo Nucifera

Gaertn.

Nelumbium speciosum

Family: Nymphaeaceae.

Habitat: Throughout warmer parts of India, up to 1,800 m.

English: East Indian Lotus, Sacred Lotus.

Ayurvedic: Kamala, Padma, Nalina, Aravinda, Jalaja, Raajeeva, Pushkara, Ambuja, Abja, Pankaja. Pundarika (whitish), kokanada (red), Indivara (Bluish).

Unani: Used as a substitute for Nilofar.

Siddha/Tamil: Thaamarai, Ambel.

Action: Filament—astringent and haemostatic. Prescribed for bleeding piles and menorrhagia. Flowers—a decoction is given in cholera, fever, strangury, palpitation of heart. Rhizomes—given in piles, chronic dyspepsia and dysentery; applied externally to cutaneous eruptions, scabies and ringworm. Rhizome-arrowroot— given to children in diarrhoea and dysentery. Root—astringent, diuretic, antiemetic, cooling. Used for dysentery, dyspepsia, piles, skin affections and for its anticoagulant properties.

The Ayurvedic Pharmacopoeia ofIn- dia recommends dried rhizomes, with roots attached at nodes, in syncope and vertigo.

Flowers yielded quercetin, luteolin and their glycosides and kaempferol glycosides. Leaves gave quercetin, iso- quercitrin and leucoanthocyanidin.

Isoquinoline alkaloid, nuciferin, is neuroleptic. Active agents in the leaves are the alkaloids, nelumbin and roe- merin.

Dosage: Dried flower—12-24 g for decoction (API, Vol. II); rhizomes— 5-10 m powder; 10-20 ml juice (API, Vol. III). Seed—3-6 g powder; flower—10-20 ml juice. (CCRAS.)... nelumbo nucifera

Nematocyst

The stinging cells present on the tentacles (and the bell of some species) of cnidarian. Each nematocyst consists of an coiled tube which may be bathed in venom. When the trigger on the outside of the nematocyst is touched, the tube rapidly inverts itself firing rather like a harpoon into the tissues of the prey. Venom on the outside of this tube is thus deposited in the tissues, and possibly into blood vessels during this trajectory. Finally, in some specialised nematocysts venom is then discharged through the open end of this thread tube and is deposited in the tissues o f the prey.... nematocyst

Nemera

(Hebrew) Resembling a leopard Nemerah, Nemerra, Nemeria, Nemerea, Nemerya, Nemra... nemera

Nemesis

(Greek) In mythology, goddess of vengeance

Nemisiss, Nemisys, Nemisyss, Nemysis, Nemysiss, Nemysys, Nemysyss... nemesis

Neneca

(Spanish) Form of Amelia, meaning “one who is industrious and hardworking” Nenecah, Nenica, Nenneca, Nennica... neneca

Neola

(Greek) One who is youthful Neolla, Neolah, Neollah... neola

Neoma

(Greek) Born under the new moon Neomea, Neomenia, Neomia, Neomenea, Neomah, Neona, Neonea, Neonia, Neonah... neoma

Neonatal

Pertaining to the ?rst month of life.... neonatal

Neonatal Intensive Care

The provision of a dedicated unit with special facilities, including one-to-one nursing and appropriate technology, for caring for premature and seriously ill newborn babies. Paediatricians and neonatologists are involved in the running of such units. Not every maternity unit can provide intensive care: for example, the provision of arti?cial ventilation, other than as a holding procedure until a baby can be transferred to a better-equipped and better-serviced unit. Such hospitals tend to have special-care baby units, which are capable of looking after the needs of most, but not all, premature or ill babies.... neonatal intensive care

Neonatal Mortality

Neonatal mortality is the mortality of infants under one month of age. In England and Wales this has fallen markedly in recent decades: from more than 28 per 1,000 live births in 1939 to 3.6 in 2002. This improvement can be attributed to various factors: better antenatal supervision of expectant mothers; care to ensure that expectant mothers receive adequate nourishing food; improvements in the management of the complications of pregnancy and of labour; and more skilled resuscitation at birth for those who need it.

Nearly three-quarters of neonatal deaths occur during the ?rst week of life. For this reason, increasing emphasis is being laid on this initial period of life. In Britain, in the last four decades of the 20th century, the number of deaths in the ?rst week of life fell dramatically from 13.2 to just over 2.7 per 1,000 live births. The chief causes of deaths in this period are extreme prematurity (less than 28 weeks’ gestation), birth asphyxia with oxygen lack to the brain, and congenital abnormalities. After the ?rst week the commonest cause is infection.... neonatal mortality

Nephele

(Greek) In mythology, a nymph created from a cloud

Nephelle, Nephel, Nephell, Nephelia, Nephelea... nephele

Nepholithiasis

Presence of renal c alculi... nepholithiasis

Nepal Tea

Nepal Tea is a type of black teathat gets its name from the South-Asian country of origin. It is a bright yellow tea which has a delicate floral aroma and combines the ripe fruit sweetness with a tinge of bitterness. This fruity tea is hand-processed and considered one of the best teas in the world, similar in flavour to the more famous Darjeeling Tea. Nepal Tea brewing The first rule of tea-making is the use of fresh water which maintains the flavour intact. Nepal black tea brewingshould last two or three minutes, up to five minutes for a stronger taste, but take care not to over-brew it, because both the aroma and the taste will be spoiled. You can prolong the brewing time only if you want to add milk or sugar to your cup of tea. When to drink Nepal Tea You can sip Nepal Tea at any point during the day because it is a fruity refined beverage, ideal for experiencing an energy surplus. Nepal Tea Health Benefits Nepal Tea consumption can bring numerous health benefits for individuals. People who drink black tea are generally healthier; they have a considerably lower rate of heart attacks or strokes, as well as lower risks of ever suffering from certain types of cancer, such as colon and lung cancer. Research shows that drinking black tea also decreases the risk of osteoporosis and diabetes and improves teeth health. Nepal Tea Side Effects Like other types of black tea, Nepal black Tea contains caffeine which increases mental alertness, but may also lead to insomnia and anxiety. When consumed in large quantities, it may cause unpleasant digestive side effects such as upset stomach symptoms. In a busy and crowded world, almost everyone could use a little bit of help to boost up their energy and at the same time, increase their mental alertness. Apart from having an enchanting aroma, Nepal Tea brings tremendous benefits by relieving stress and keeping tea drinkers stay alert at the same time.... nepal tea

Nepeta Cataria

Linn.

Family: Labiatae, Lamiaceae.

Habitat: Cultivated in Britain and the USA. Occurs in Himalayas from Kashmir to Nepal at 2,000-3,300 m.

English: Catnip, Catnep, Catmint.

Action: Leaves and flowers— gentle nerve relaxant and sedative, carminative, antispasmodic, an- tidiarrhoeal, diaphoretic, febrifuge. Used in restlessness, convulsions, nervous headache, colic, early stages of fever, colds and influenza. The herb is to be infused (not boiled).

Catnip contains iridoids, tannins and volatile oil, major components being alpha- and beta-nepetalactone (up to 42%), citronellol and geraniol.

The catnip response in the domestic cat is being attributed to iridoid lac- tones, nepetalactone, dihydronepeta- lactone, iso-dihydronepetalactone and neonepetalactone. Its reputation as a hallucinogen has been disputed, but a few studies have shown behavioural effects, although weak, in young chicks, rodents and cats. (Potter's New Cyclopaedia.)

Neptalactone is structurally related to valepotriates found in valerian. (Natural Medicines Comprehensive Database, 2007.)... nepeta cataria

Nepeta Hindostana

(Roth) Haines.

Synonym: N. ruderalis Buch-Ham. ex Benth.

Family: Labiatae; Lamiaceae.

Habitat: Punjab, Uttar Pradesh, Bihar, West Bengal, Madhya Pradesh and South India up to 2,400 m. (Blue-flowered var.)

Unani: Baadranjboyaa, Billilotan. Also equated with Melissa officinalis.

Action: See Nepeta cataria.

The alcoholic extract of the plant yielded a triterpenoid aldehyde, nepe- hinal. Nepetidone, nepedinol, and a triterpenic acid have also been reported. The plant contains flavonoids including nepitrin, dinatin, nepetin. Flowers and stem gave napetol, hen- triacontane and beta-sitosterol. An aqueous extract of flowers contained Na, K, Ca, Mg, Zn, Cd, Cu, Ni, Mn and Fe. Alcoholic extract of the plant produced marked hypocholesterolaemic effect in experimental animals. It also produced beneficial effects in the histopathology of myocardial infarction. Aqueous extract of the plant, given intravenously, lowered the blood pressure in dogs by 26.87%. It also showed CNS depressant and sedative activities. (In Indian medicine, the plant is used in various cardiac conditions including cardiac asthma.)... nepeta hindostana

Nephthys

(Egyptian) In mythology, one of the nine most important deities; the lady of the house... nephthys

Neptunine

(Latin) Feminine form of Neptune, the god of the sea Neptuna, Neptunia, Neptunea, Neptunina, Neptuninia, Neptuninea... neptunine

Nera

(Hebrew) Resembling a flickering candle; born during Hannukah Nerah, Neriya, Nerit... nera

Neptunia Oleracea

Lour.

Synonym: N. prostrata Baill.

Family: Mimosaceae.

Habitat: Throughout India, in tanks.

Ayurvedic: Lajjaalu (var.), Alam- bushaa. (Provisional synonyms.)

Siddha: Sadai, Sundaikkirai.

Folk: Paani-lajak (Punjab).

Action: Astringent, refrigerant.

Mimosa pudica Linn. is the accepted source of the classical herb Lajjaalu. It is used as astringent and styptic.... neptunia oleracea

Nerea

(Basque) Daughter of mine Nereah, Neria, Neriah... nerea

Nereida

(Greek) A sea nymph; in mythology, the Nereids were mermaids Nereyda, Nerida, Nireida, Nerine, Narine, Nerida, Nerina, Neried, Nerin, Ninfa... nereida

Nerio

(Latin) In mythology, the wife of the god of war... nerio

Nerissa

(Italian / Greek) A black-haired beauty / form of Nereida, meaning “a sea nymph”

Narissa, Naryssa, Nericcia, Neryssa, Narice, Nerice, Neris... nerissa

Nerita

(Greek) Woman from the sea Neritah, Nereeta, Nereetah, Neryta, Nerytah, Nirita, Nireta, Nyrita, Nyreta, Nereata, Nereatah... nerita

Nerium Indicum

Mill.

Synonym: N. odorum Soland.

Family: Apocynaceae.

Habitat: Native of Mediterranean region; grown in Indian gardens.

English: Indian oleander, White oleander.

Ayurvedic: Karavira, Viraka, Ashva- maaraka, Hayamaaraka, Gauripush- pa, Divyapushpa, Shatakumbha, Siddhapushpa (white-flowered var.). Raktapushpa, Raktaprasava, Ravipriya (red-flowered var.)

Unani: Kaner Safed, Diflaa, Samm-ul-maar, Khar-zaharah.

Siddha/Tamil: Arali, Alari, Aatrulari, Karaviram.

Action: Root—resolvent and attenuant. A paste of the root is externally applied to haemorrhoids and ulcerations in leprosy. Paste of the root bark and leaves is used in ringworm and other skin diseases. An oil extracted from the root bark is used in skin diseases of scaly nature. Leaves—cardioactive (digitalis-like effect) and diuretic, anti-inflammatory, antifungal, insecticidal. Toxic.

The leaves contain several glyco- sides including glycosides of 8 beta- hydroxy-digitoxigenin. Cardenolide glycosides and pregnanolone glyco- sides have been isolated from roots.

The ethanolic extract of the flowers inhibits the growth of dermatophytes.

The plant shows antifungal activity against ringworm fungus, Microspo- rum nanum.

Dosage: Detoxified leaves—30— 125 mg powder (API, Vol. I); root— 30 mg—125 mg powder (API, Vol. III).... nerium indicum

Nerola

(Italian) Resembling the orange flower

Nerolia, Nerolie, Nerolea, Neroli, Neroley, Neroly, Nerolee, Neroleigh... nerola

Nerthus

(German) In mythology, goddess of fertility Nerthos, Nerthous... nerthus

Nerves Twelve Nerves Come Off The Brain:

I. Olfactory, to the nose (smell).

II. Optic, to the eye (sight).

III. Oculomotor

Trochlear, to eye-muscles.

Abducent

VI. Trigeminal, to skin of face.

VII. Facial, to muscles of face.

VIII. Vestibulocochlear, to ear (hearing and balancing).

IX. Glossopharyngeal, to tongue (taste).

X. Vagus, to heart, larynx, lungs, and stomach.

XI. Spinal accessory, to muscles in neck.

XII. Hypoglossal, to muscles of tongue.... nerves twelve nerves come off the brain:

Nervilia Aragoana

Gaudich.

Synonym: Pogonia flabelliformis Lindl.

Family: Orchidaceae.

Habitat: Tropical Himalayas from Garhwal eastwards at altitudes of 1,200-1,500 m and in Bihar, Konkan, North Kanara and Travancore.

Ayurvedic: Padmachaarini, Shankhaaluka. (Sthala Kamala is a doubtful synonym.)

Action: Astringent, diuretic (used in dysuria).

A decoction of leaves is given after parturition.... nervilia aragoana

Nerium Oleander

Linn.

Family: Apocynaceae.

Habitat: Native to Mediterranean region; grown in Indian gardens.

English: Red Oleander, Rose Bay.

Unani: Surkh Kaner.

Action: See N. indicum. (The white- and red-flowered varieties are equated with Nerium oleander; both possess similar properties. The yellow-flowered variety is equated with Thevetia peruviana.)

Key application: Leaf—included among unapproved herbs by German Commission E. Positively inotropic and negatively chronotropic actions have been mentioned; the use of leaf for diseases and functional disorders of the heart, as well as for skin diseases has been indicated.

The leaves and roots gave a number of active principles including gly- cosides, terpenoids, sterols and other compounds. Cardiac steroids, isolated from the leaf, include oleandrin, gen- tiobiosyl oleandrin, odoroside. The stem contained alanine arginine, as- partic acid, cysteine, glutamic acid, glycine, histidine, leucine, isoleucine, lysine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine and valine. A polysaccharide (2.3%), containing galacturonic acid, rhamnose, arabinose and galactose has been isolated from leaves.

Neutral fraction from leaves at low doses caused marked suppression of locomotor activity.

Aqueous extract of leaves showed significant antibacterial activity against Pseudomonas aeruginosa. The leaves also showed insecticidal activity.... nerium oleander

Nerves, Injuries To

These have several causes. Continued or repeated severe pressure may damage a nerve seriously, as in the case of a crutch pressing into the armpit and causing drop-wrist. Bruising due to a blow which drives a super?cially placed nerve against a bone may damage, say, the radial nerve behind the upper arm. A wound may sever nerves, along with other structures; this accident is specially liable to occur to the ulnar nerve in front of the wrist when a person accidentally puts a hand and arm through a pane of glass.

Symptoms When a sensory nerve is injured or diseased, sensation is immediately more or less impaired in the part supplied by the nerve. Ulceration or death of the tissue supplied by the defective nerve may occur. When the nerve in question is a motor one, the muscles governed through it are instantly paralysed. In the latter case, the portion of nerve beyond the injury degenerates and the muscles gradually waste, losing their power of contraction in response to electrical applications. Finally, deformities result and the joints become ?xed. This is particularly noticeable when the ulnar nerve is injured, the hand and ?ngers taking up a claw-like position. The skin may also be affected.

Treatment Damaged or severed (peripheral) nerve ?bres should be sewn together, using microsurgery. Careful realignment of the nerve endings gives the ?bres an excellent chance of regenerating along the right channels. Full recovery is rare but, with regular physiotherapy to keep paralysed muscles in good shape and to prevent their shortening, the patient can expect to obtain a reasonable return of function after a few weeks, with improvement continuing over several months.... nerves, injuries to

Nervous Impulse

This is transmitted chemically, by the formation at nerve-endings of chemical substances. When, for example, a NERVE to a muscle is stimulated, there appears at the NEUROMUSCULAR JUNCTION the chemical substance, ACETYLCHOLINE. Acetylcholine also appears at endings of the parasympathetic nerves (see NERVOUS SYSTEM) and transmits the e?ect of the parasympathetic impulse. When an impulse passes down a sympathetic nerve, the e?ect of it is transmitted at the nerve-ending by the chemical liberated there: ADRENALINE or an adrenaline-like substance.... nervous impulse

Nervous System, Disorders Of

The following conditions are discussed under their individual headings: APHASIA; BRAIN, DISEASES OF; CATALEPSY; CHOREA; CRAMP; EPILEPSY; HYSTERIA; LEARNING DISABILITY; MEMORY; MENTAL ILLNESS; MULTIPLE SCLEROSIS (MS); NERVES, INJURIES TO; NEURALGIA; NEURITIS; PARALYSIS; PSYCHOSOMATIC DISEASES; SPINE AND SPINAL CORD, DISEASES AND INJURIES OF; STROKE; TABES.... nervous system, disorders of

Nerys

(Welsh) A daughter born into nobility Neris, Neriss, Neryss, Nerisse, Nerysse

... nerys

Nessa

(Hebrew / Greek) A miracle child / form of Agnes, meaning “one who is pure; chaste”

Nesha, Nessah, Nessia, Nessya, Nesta, Neta, Netia, Nessie, Nessy, Nessi, Nessey, Nessee, Nest, Nestia, Nesy, Netta, Netah, Nettah, Neysa, Niesha... nessa

Nethinim

(Hebrew) Those who are set apart; given

Nethinima, Nethynima, Nethynym, Nethynyma, Nethinimia, Nethinimea... nethinim

Netis

(Native American) One who is trustworthy

Netiss, Netisse, Netys, Netyss, Netysse... netis

Network

An affiliation of providers through formal and informal contracts and agreements. Networks may contract externally to obtain administrative and financial services. The term can also refer to an individual’s social network. See “social network”.... network

Network Adequacy

Standards for provider networks to maintain sufficient numbers and types of providers to ensure accessibility of services without unreasonable delays.... network adequacy

Neuracanthus Sphaerostachyus

Dalz.

Family: Acanthaceae.

Habitat: Western Ghats, Deccan and Gujarat.

Folk: Ganther (Gujarat and Maharashtra), Ghosa-vel (Maharashtra).

Action: Root-paste applied to ringworm.... neuracanthus sphaerostachyus

Neurodermatoses

See under SKIN, DISEASES OF.... neurodermatoses

Neurofibrils

A microscopic strand of CYTOPLASM that occurs in the cell body of a NEURON(E) as well as in the semi?uid content of the AXON of a nerve cell.... neurofibrils

Neurofibromatosis

See VON RECKLINGHAUSEN’S DISEASE.... neurofibromatosis

Neuroleptics

Drugs used to quieten disturbed patients, whether this is the result of brain damage, MANIA, DELIRIUM, agitated DEPRESSION or an acute behavioural disturbance. They relieve the ?orid PSYCHOTIC symptoms such as hallucinations and thought-disorder in SCHIZOPHRENIA and prevent relapse of this disorder when it is in remission.

Most of these drugs act by blocking DOPAMINE receptors. As a result they can give rise to the extrapyramidal effects of PARKINSONISM and may also cause HYPERPROLACTINAEMIA.

Troublesome side-effects may require control by ANTICHOLINERGIC drugs. The main antipsychotic drugs are: (i) chlorpromazine, methotrimeprazine and promazine, characterised by pronounced sedative effects and a moderate anticholinergic and extrapyramidal e?ect; (ii) pericyazine, pipothiazine and thioridazine, which have moderate sedative effects and marked anticholinergic effects, but less extrapyramidal effects than the other groups; (iii) ?uphenazine, perphenazine, prochlorperazine, sulpiride and tri?uoperazine, which have fewer sedative effects and fewer anticholinergic effects, but more pronounced extrapyramidal effects.... neuroleptics

Neuromuscular Blockade

In clinical practice, the transmission of impulses at the NEUROMUSCULAR JUNCTION may be blocked to paralyse temporarily a patient for a surgical procedure, or to assist treatment on the intensive care unit. There are two main types of drug, both of which competitively block the ACETYLCHOLINE receptors on the motor end plates. (1) Depolarising neuromuscular blocking agents: these act by ?rst producing stimulation at the receptor, and then by blocking it. There are characteristic muscle fasciculations before the rapid onset of paralysis which is of short duration (less than ?ve minutes with the commonly used drug, suxamethonium). The drug is removed from the receptor by the enzyme, CHOLINESTERASE.

(2) Non-depolarising neuromuscular blocking agents: these drugs occupy the receptor and prevent acetylcholine from becoming attached to it. However, in su?ciently high concentrations, acetylcholine will compete with the drug and dislodge it from the receptor; the e?ect of these drugs is reversed by giving an anticholinesterase, which allows the amount of acetylcholine at the neuromuscular junction to build up. These drugs have varying durations of action, but all are slower in onset and of longer duration than the depolarisers.... neuromuscular blockade

Neurone

The cell of a nerve responsible for transmission of the signal along the nerve fibre.... neurone

Neuropathies

A disease of the central or peripheral nervous systems. In more common reference, a neuropathy is primarily a disorder of peripheral nerves. CNS diseases are often life threatening; neuropathies are generally disorders of the control and sensory nerves out in the body.... neuropathies

Neuron(e)

Also known as a nerve cell, this is the basic cellular building-block of the NERVOUS SYSTEM, which contains billions of neurones linked in a complex network and acting in di?erent combinations to keep the body informed about the outside world, and then to organise and activate appropriate responses. There are three main types of neurone:

Sensory These carry signals to the central nervous system (CNS) – the BRAIN and SPINAL CORD – from sensory receptors. These receptors respond to di?erent stimuli such as touch, pain, temperature, smells, sounds and light.

Motor These carry signals from the CNS to activate muscles or glands.

Interneurons These provide the interconnecting ‘electrical network’ within the CNS.

Structure Each neurone comprises a cell body, several branches called dendrites, and a single ?lamentous ?bre called an AXON. Axons may be anything from a few millimetres to a metre long; at their end are several branches acting as terminals through which electrochemical signals are sent to target cells, such as those of muscles, glands or the dendrites of another axon.

Axons of several neurones are grouped

together to form nerve tracts within the brain or spinal cord or nerve-?bres outside the CNS. Each nerve is surrounded by a sheath and contains bundles of ?bres. Some ?bres are medullated, having a sheath of MYELIN which acts as insulation, preventing nerve impulses from spreading beyond the ?bre conveying them.

The cellular part of the neurones makes up the grey matter of the brain and spinal cord – the former containing 600 million neurones. The dendrites meet with similar outgrowths from other neurones to form synapses. White matter is the term used for that part of the system composed of nerve ?bres.

Functions of nerves The greater part of the bodily activity originates in the nerve cells (see NERVE). Impulses are sent down the nerves which act simply as transmitters. The impulse causes sudden chemical changes in the muscles as the latter contract (see MUSCLE). The impulses from a sensory ending in the skin pass along a nerve-?bre to affect nerve cells in the spinal cord and brain, where they are perceived as a sensation. An impulse travels at a rate of about 30 metres (100 feet) per second. (See NERVOUS IMPULSE.)

The anterior roots of spinal nerves consist of motor ?bres leading to muscles, the posterior roots of sensory ?bres coming from the skin. The terms, EFFERENT and AFFERENT, are applied to these roots, because, in addition to motor ?bres, ?bres controlling blood vessels and secretory glands leave the cord in the anterior roots. The posterior roots contain, in addition to sensory ?bres, the nerve-?bres that transmit impulses from muscles, joints and other organs, which among other neurological functions provide the individual with his or her

proprioceptive faculties – the ability to know how various parts of the body are positioned.

The connection between the sensory and motor systems of nerves is important. The simplest form of nerve action is that known as automatic action. In this, a part of the nervous system, controlling, for example, the lungs, makes rhythmic discharges to maintain the regular action of the respiratory muscles. This controlling mechanism may be modi?ed by occasional sensory impressions and chemical changes from various sources.

Re?ex action This is an automatic or involuntary activity, prompted by fairly simple neurological circuits, without the subject’s consciousness necessarily being involved. Thus a painful pinprick will result in a re?ex withdrawal of the affected ?nger before the brain has time to send a ‘voluntary’ instruction to the muscles involved.

Voluntary Actions are more complicated than re?ex ones. The same mechanism is involved, but the brain initially exerts an inhibitory or blocking e?ect which prevents immediate re?ex action. Then the impulse, passing up to the cerebral hemispheres, stimulates cellular activity, the complexity of these processes depending upon the intellectual processes involved. Finally, the inhibition is removed and an impulse passes down to motor cells in the spinal cord, and a muscle or set of muscles is activated by the motor nerves. (Recent advances in magnetic resonance imaging (MRI) techniques have provided very clear images of nerve tracts in the brain which should lead to greater understanding of how the brain functions.) (See BRAIN; NERVOUS SYSTEM; SPINAL CORD.)... neuron(e)

Neurotic

A vague term applied to a person of nervous temperament, whose actions are largely determined by emotions or instincts rather than by reason.... neurotic

Neutron

A neutron is one of the particles that enter into the structure of the atomic nucleus. (See ISOTOPE.)... neutron

Neutrophils

Another name for polymorphonuclear leukocytes, the most common type of blood-carried white blood cell, and the first mobile resistance cell to come to the rescue in injury.... neutrophils

Neva

(Latin) From the place covered with snow

Nevah, Neve, Nevara, Nevarra, Nevaria, Nevarea, Nieve, Neiva, Nieva, Neive... neva

Nevada

(Latin) From the state of Nevada; form of Neva, meaning “from the place covered with snow”... nevada

Nevaeh

(American) Child from heaven... nevaeh

Neveah

(Slavic) Resembling a butterfly Nevea, Neviah, Neviya, Nevia, Neviyah... neveah

Nevina

(Scottish) Feminine form of Nevin; daughter of a saint Nevinah, Neveena, Nevyna, Nevinne, Nevynne, Neveene, Neveana, Neveane... nevina

Newlyn

(Gaelic) Born during the spring Newlynn, Newlynne, Newlin, Newlinn, Newlinne, Newlen, Newlenn, Newlenne... newlyn

Neylan

(Turkish) The child of our desire Neylana, Neylanna, Neylann, Neylanne, Neylane... neylan

Neziah

(Hebrew) One who is pure; a victorious woman

Nezia, Nezea, Nezeah, Neza, Nezah, Neziya, Neziyah... neziah

Olfactory Nerves

The nerves of SMELL. Each nerve detects smell by means of hair-like receptors positioned in the mucous membrane lining the roof of the nasal cavity (see NOSE).... olfactory nerves

Peripheral Neuritis

In?ammation of the nerves (see NERVE) in the outlying parts of the body. (See NEURITIS.)... peripheral neuritis

Predictive Value Negative

The probability that a person with a negative test is free of the disease and is not a false negative.... predictive value negative

Recurrent Laryngeal Nerve

A branch of the vagus NERVE which leaves the latter low down in its course, and – hooking around the right subclavian artery on the right side and round the arch of the aorta on the left

– runs up again into the neck, where it enters the larynx and supplies branches to the muscles which control the vocal cords.... recurrent laryngeal nerve

Potentilla Nepalensis

Hook.

Family: Rosaceae.

Habitat: The Himalayas from Kashmir to Kumaon.

Folk: Ratanjot (substitute).

Action: Rootstocks—depurative; ash, mixed with oil, is applied to burns.

Unani: Baadiyaan-kohi, Karafs-e- kohi, Fitraasaaliyun (also equated with Petroselinum crispum Mill. Nym. ex auct. Kew.).

Folk: Komal.

Action: Root and fruit—diuretic, emmenagogue. An infusion of root is given for indigestion and irregular menses.

The roots and umbels yielded cou- marins and their glycosides. Osthol (7-methoxy-8-isop entenyl-coumarin), which occurs in the dried roots up to the extent of 3.6%, has been found to be a potent respiratory and circulatory stimulant in experimental animals. Its respirotonic effect was more marked than that of coramine, leptazol and caffeine.... potentilla nepalensis

Rural Health Network

Any of a variety of organizational arrangements to link rural health care providers in a common purpose.... rural health network

Sea Nettle

Colloquial term for the north American jellyfish Chrysaora quinquecirrha.... sea nettle

Silver Needle Tea

Silver Needle tea is a rare type of white tea,with a delicate flavor and great health benefits. Recommended to consumers willing to reduce the amount of caffeine, it is a special beverage both for connoisseurs and beginners. About Silver Needle Tea Silver Needle Tea is a type of white tea, originating from the Chinese Fuding county, and considered to be the finest type of this kind of tea. It was once reserved to Royal Chinese Family due to its benefits and rareness. Silver Needle Tea is hand-harvested only two days a year, during spring. It contains only the unopened tea buds, one of the reasons the Royal Family was the only one to drink it. Silver Needle Tea brewing Silver Needle Tea has a subtle taste and a low quantity of caffeine. It is recommended to consumers searching for the benefits of green tea, but not enjoying its strong flavor .
  • Silver Needle tea brews best with water at 180 degrees Fahrenheit (the water should be almost boiling, but not rolling)
  • After adding the water to the tea, steep it for five minutes
  • In case of adding more tea to the pot, it needs three minutes to steep
Silver Needle Tea benefits Being a whitetea, Silver Needle tea is helpful in cancer prevention, due to its high content of antioxidants. These compounds are able to fight free radicals, best known for causing tumors growth and spreading cancer cells. Silver Needle tea properties were also acknowledged to:
  • detoxify the body
  • relieve stress
  • lift mood
Silver Needle Tea side effects Silver Needle Tea has few side effects, especially related to overconsumption. It is indicated that individuals suffering from cardiac problems or hypertension should consume it moderately. Silver Needle teais a good choice for consumers who want to keep a good physical and mental state, enjoying both a delicate taste and a healthy beverage.... silver needle tea

Social Network

An individual’s web of kinship, friendship and community ties.... social network

Social Network Care

See “informal care”.... social network care

Transcutaneous Electrical Nerve Stimulation (tens)

A method of electrical stimulation that is being used for the relief of PAIN, including that of MIGRAINE, NEURALGIA and phantom limbs (see AMPUTATION). Known as TENS, its mode of action appears to have some resemblance to that of ACUPUNCTURE. Several controlled trials suggest that it provides at least a modicum of relief of pain after operations, thereby reducing the amount of ANALGESICS that may be called for.... transcutaneous electrical nerve stimulation (tens)

Trap Nets

Nets used to sample the living mosquito population. By permitting access to a bait but restricting movement away from it, trap nets tend to concentrate female mosquitoes near the bait.... trap nets

Trichosanthes Nervifolia

Linn.

Family: Cucurbitaceae.

Habitat: Karnataka, Kerala and Tamil Nadu.

Ayurvedic: Patoli (related species of Patola).

Siddha/Tamil: Kombu Pudalai.

Action: Herb—bitter tonic, febrifuge. Root—purgative. Fruit— used as dentifrice.... trichosanthes nervifolia

Tea For Nerves

Nerve damage can include neuropathy or neuritis, which can be caused by diabetes, nerve injury, autoimmune disease, viral infections, muscle spasms or vitamin deficiencies. Traditional medicine found a lot of treatments for nerve damage, but alternative medicine fans think that you don’t need to take a lot of pills for something that can be treated with just a cup of tea. How a Tea for Nerves Works A Tea for Nerves’ main purpose is to nourish your nervous system and induce a state of relaxation to all your nervous cells. Also, these teas can reconstruct the damaged tissue and make your body heal all affected areas. In order to be useful, a Tea for Nerves needs to contain tannins, volatile oils and minerals (manganese, magnesium, iron, preferably). Efficient Tea for Nerves When choosing a Tea for Nerves, remember that it must be both one hundred percent safe and very efficient. If you don’t know which teas to choose from, here’s a list to help you out: - Saint John’s Wort Tea – is useful for sciatica and it can bring relief to patients suffering from depression and spinal nerves damages. Take only a cup per day and avoid it at all costs if you’re on antidepressants. Also, if you’re pregnant, talk to your doctor before starting a treatment based on Saint John’s Wort Tea. - Skullcap Tea – treats a number of affections such as inflammation, arteriosclerosis, high cholesterol and epilepsy thanks to its active constituents: antioxidant flavonoids, which can repair the nervous damages and baicalin (has anti-spastic and nerve-relaxant properties). Don’t take more than 2 cups per day for a short amount of time and don’t combine it with anti-depressants and sedatives. Basil Tea – this Tea for Nerves has many medical uses and not only that it can repair the nervous ailments, but it’s also a great energy and health enhancer. You can also use it to treat asthenia, anemia, loss of appetite and digestive tract problems. Drink one or two cups per day for a short amount of time and enjoy the health benefits! Tea for Nerves Side Effects When taken properly, these teas are generally safe. However, make sure you don’t exceed the number of cups recommended per day or you’ll get diarrhea, constipation, nausea, headaches or skin rashes. If you’ve been taking one of these teas for a while and you’re experiencing some unusual reactions, talk to your doctor as soon as possible! Don’t take a Tea for Nerves if you’re pregnant, breastfeeding, on blood thinners, anticoagulants or preparing for a major surgery (these teas contains substances that may interfere with your anesthetic). The same advice for children: there are no studies to examine the treatment’s effect on them. If your doctor says it’s ok to try a Tea for Nerves, choose one that fits best your needs and enjoy its wonderful health benefits!... tea for nerves

Viburnum Nervosum

Hook. f. & Thoms.

Synonym: V. grandiflorum Wall. ex DC.

Family: Caprifoliaceae.

Habitat: The Himalayas from Kashmir to Sikkim at altitudes of 3,000-4,000 m.

Ayurvedic: Tilvaka.

Folk: Telam, Timoi (Kumaon), Tilen, Thelkaa (Garhwal).

Action: Bark—astringent; contain 13.1% tannin on dry basis.... viburnum nervosum

Tea For Nervous System

The nervous system is responsible for almost any reaction that comes from your body. From eyes to muscles and even hair, your body is a very complex electric system directed by your brain. Most of the problems that a person has in a lifetime are related to a nervous system failure. In order to treat this kind of problems or prevent them from happening, you may want to try a tea instead of all those traditional pills. How a Tea for Nervous System Works A Tea for Nervous System is indeed helpful if it contains an important amount of nutrients, enzymes, tannins, volatile oils and minerals (sodium, iron, magnesium and manganese). You may want to avoid a tea that has an elevated acids level since it may cause you even more damages. A Tea for Nervous System will make your body send all the active constituents to the affected areas and heal the damaged tissue. Efficient Tea for Nervous System In order to work properly, a Tea for Nervous System must show results in a short time period and be one hundred percent safe (you don’t want any more complications than you already have). However, before starting any kind of herbal treatment, remember to take the indicated dose and never surpass it in order to avoid other health problems. If you don’t know which teas could be helpful for you, here’s a list for guidance: - Oolong Tea – contains half the amount of caffeine that other teas have so it’s best for your health to give it a try every once in a while. This Tea for Nervous System will also strengthen your entire organism and rejuvenate the aspect of your skin. However, don’t drink more than 2 cups per day. - Green Tea – as the scientists have proved, this decoction contains all the ingredients necessary to sustain life, so it’s good for a number of other health complaints, such as infertility, headaches, nausea, loss of appetite, anemia and asthenia. Just make sure you avoid it at all costs in case you’re experiencing some menstrual or menopausal symptoms (it may cause uterine contractions and internal bleedings). - Black Tea – some say that it does more damages than good for your nervous system and some others think that this tea is worth a try. Having an elevated level of caffeine, this tea is highly addictive. In right amount, it can treat infertility, erectile dysfunctions, sore throats and colds. However, ask an herbalist before starting a treatment based on this Tea for Nervous System in order to find out which are the risks. Tea for Nervous System Side Effects When taken according to specifications, these teas are generally safe. However, exceeding the number of cups recommended per day may lead to other health complaints, such as nausea, diarrhea, uterine contractions, internal bleedings and headaches. If you’ve tried one of these teas and something doesn’t feel quite right, talk to your doctor as soon as possible! Don’t take a Tea for Nervous System if you’re pregnant, breastfeeding, on blood thinners or anticoagulants. The same advice if you’re preparing for a surgery (some of the active compounds in these teas may interfere with your anesthetic and cause death). But if you have the green light from your doctor, choose a tea that fits best your requirements and enjoy its wonderful health benefits!... tea for nervous system

Vasomotor Nerves

Small nerve ?bres that lie upon the walls of blood vessels and connect the muscle ?bres of their middle coat with the NERVOUS SYSTEM. Through these nerves the blood vessels are retained in a state of moderate contraction. There are vasodilator nerves, through which are transmitted impulses that dilate the vessels, and, in the case of the skin vessels, produce the condition of blushing; there are also vasoconstrictor nerves which transmit impulses that constrict, or narrow, the blood vessels – as occurs on exposure to cold (see HYPOTHERMIA). Various drugs produce dilatation or contraction of the blood vessels, and several of the substances produced by ENDOCRINE GLANDS in the body have these effects: for example, ADRENALINE.... vasomotor nerves

Vitex Negundo

Linn.

Family: Verbenaceae.

Habitat: Throughout India in the warmer zones; ascending to 900 m in the North-western Himalaya.

English: Five-leaved Chaste tree.

Ayurvedic: Nirgundi, Shephaa- likaa, Sindhuka, Sindhuvaara, Suvahaa, Sugandhikaa. Nila, Nila- nirgundi, Shveta nirgundi (var.). White-flowered var. is known as Sinduvaara, blue-flowered as Nirgundi or Shephaali,

Unani: Sambhaalu, Fanjankisht.

Siddha/Tamil: Nochi, Nalla Nochi, Vellai Nochchi, Nirkundi.

Action: Seeds—prescribed in spermatorrhoea, and for promoting spermiogenesis (in Unani medicine). Also given as a rejuvenating tonic for retarding old age and for retaining and promoting virility. (in Ayurvedic medicine). Leaf—anti-inflammatory, analgesic; removes foetid discharges and worms from ulcers. Flowers—astringent, febrifuge, antidiarrhoeic; prescribed in liver complaint. Oil— applied to sinus, scrofulous sores.

The Ayurvedic Pharmacopoeia of India recommends the leaf (also the root) in excessive vaginal discharges, oedema, skin diseases, pruritus, helmin- thiasis, rheumatism, and puerperal fever.

A water extract of the leaves, when administered to rats, exhibited anti- inflammatory, analgesic, antihistami- nic and membrane stabilizing and an- tioxidant activities. (J. Ethnopharmo- col, 2003, (203), 199-206.) Methano- lic extract of leaves showed remarkable antihistaminic activity.

The leaves contain iridoid glyco- sides, isomeric flavanones and flavo- noids, besides casticin and the gluco- sides, luteolin-7-glucoside and alpha- D-glucoside of a tetrahydroxy mono- methoxy flavone.

Dried powder of roots contains hen- triacontane, beta-sitosterol and its aetat and stigmasterol. Alcoholic extract of the root showed 40-60% antiimplantation activity with no anti- ovulatory effect in rats.

Flavone vitexicarpin (1), isolated from the leaves, exhibited broad cyto- toxicity in human cancer cell line panel. Two pentacyclic triterpenoids, betulin- ic acid and ursolic acid, along with an aliphatic alcohol, n-hentriacontanol, beta-sitosterol and p-hydroxybenzoic acid have been isolated from leaves.

The seeds contain p-hydroxybenz- oic acid, 5-oxyisophthalic acid, glucose and the triterpene, vitextriter- pene. Several anti-inflammatory triter- penoids and flavonoids have also been isolated from the seeds. The flavanone, 5,7,3' trihydroxy-6, 8,4'-trimethoxy- flavone exhibited anti-androgenic activity in adult mice and dogs.

Dosage: Leaf—10-15 ml juice (API, Vol. III); root—10-12 ml juice (API, Vol. IV.)... vitex negundo

Anti-neoplastics

Herbs that prevent formation or destroy tumour cells. Some reported in the literature to arrest the spread of malignancy. A neoplasm is a new growth and may be malignant or non- malignant. Bayberry (intestinal), Bryonia (lung), Clivers (Genito-urinary tract), Comfrey (general), Condurango (gastric), Dandelion (liver), Echinacea, Greater Celandine (epithelial), Mandrake (face and skin), Mistletoe, Myrrh, Plantain (throat), Poke root (breast), Queen’s Delight, Red Clover (epithelial and breast), Rosebay Willowherb (gastric), Vinca rosea (leukaemia), Thuja (womb), Wild Violet (breast and womb), Yellow Dock. ... anti-neoplastics

Beer, Nettle

Gather basket of nettles, wash and place in a pan with double their quantity of water. Simmer gently one hour. Strain. To every gallon add half an ounce ground Ginger and one pound Barbados sugar or molasses. When cool, ferment with Yeast – three-quarters of an ounce to each gallon. Allow to stand until next day before bottling. Flavour is improved by juice of a lemon. ... beer, nettle

Cancer – To Neutralise Odour

Dr Desmartis, in a paper to The American Academy of Sciences announced that Logwood, (Haematoxylum campechianum) was an antiseptic of value in cancer. This was discovered by accident. Having under his care several cancer patients presenting ulcerative sores ‘emitting a nauseous odour’, he composed a plaster of equal parts of Extract of Logwood and hog’s lard. To his surprise, on application the fetter immediately disappeared. ... cancer – to neutralise odour

Dead Nettle

Lamium album L. Part used: herb.

Constituents: flavone glycosides, mucilage, tannin.

Action: anti-catarrhal.

Uses: Nasal catarrh, leucorrhoea. Anaemia.

Preparations: Tea. As a medicament or daily ‘health’ tea. 1-2 teaspoons to each cup boiling water; infuse 10-15 minutes. 1 cup as desired.

Vaginal douche: 2oz dried (or handful fresh herb) to 2 pints boiling water; infuse, and inject warm. May also be used as a lotion for skin disorders. ... dead nettle

Heart – Nervous

Condition with no specific organic lesion present, but one in which palpitation or cardiac distress may be precipitated by nervous or emotional stimuli.

Alternatives. Neuralgia of the Heart: Lobelia.

Palpitation with sense of suffocation: Pulsatilla.

From physical exhaustion: Ginseng.

With rapid heart beat: Lily of the Valley, Gelsemium.

Tea. Equal parts, Valerian, Motherwort, Lime flowers. Mix. 1-2 teaspoons to each cup boiling water allowed to cool. Drink cold 1 teacup 2 or 3 times daily.

Decoction. Equal parts, Valerian, Hawthorn, Mistletoe. Mix. 1 heaped teaspoon to each cup water simmered gently for 20 minutes. 1 teacup 2 or 3 times daily.

Tablets/capsules. Hawthorn, Mistletoe, Motherwort. Valerian. Passion flower. Lobelia.

Formula. Equal parts: Hawthorn, Lily of the Valley, Mistletoe. Dose: Powders: 500mg (two 00 capsules or one-third teaspoon). Liquid extracts: 1 teaspoon. Tinctures 2 teaspoons. Thrice daily.

Practitioner. Formula. Tincture Hawthorn 2; Tincture Gelsemium 1. Dose: 15-30 drops 2-3 times daily. Alternative formula. Tincture Valerian 2; Strophanthus 1. Dose: 15-30 drops thrice daily.

Diet. Oats (oatmeal porridge), low fat, low salt, high fibre. See also: DIET – HEART AND CIRCULATION. ... heart – nervous

Nebuliser

A dispenser designed to convert a remedy solution into a mist of droplets to effectively convey medication to the respiratory organs. Essential oils suitable for this purpose: Peppermint, Eucalyptus, “Olbas”. For asthma, bronchitis, sinusitis, hay fever.

Nebulisers should carry a warning against misuse. Failure to respond should not be a signal to increase dosage, but an indication that asthma or the complaint is deteriorating. ... nebuliser

Neoklenz

Contains Senna leaf 40 per cent, Frangula bark 22.5 per cent, Psyllium seeds 27.5 per cent, Fennel 10 per cent. For non-persistent constipation. ... neoklenz

Nerve Relaxant

See: SEDATIVE. ... nerve relaxant

Nerve Restoratives

All degenerative changes in the nervous system arise from breakdown of cell integrity through causes including stress, disease or faulty nutrition. J.M. Thurston classifies the restorative effect of herbs as:

Stomach and intestines: Wild Cherry bark, Black Haw.

Heart: Lily of the Valley, Cactus. Liver: Wild Yam.

Eye: Blue Cohosh, Poke root.

Brain: Oats, Black Cohosh.

Spine: Damiana, Oats, Kola, Unicorn root (Aletris). Hops. Womb: False Unicorn root (Helonias).

General Restoratives: St John’s Wort, Vervain. ... nerve restoratives

Nerve Stimulants

Often necessary to bring added vitality to the body or one of its parts. Often combined with circulatory stimulants to help support the nervous system in the presence of nerve weakness and paralysis.

Ephedra, Ginseng, Siberian Ginseng, Oats, Damiana, Kola, Gotu Kola, Thuja, Vervain. ... nerve stimulants

Nerve Tonics

To invigorate and restore. Regarded as nutrients for strengthening nerve fibres and their protective sheaths. Help resolve effects of stress and replace mineral deficiencies in nerve tissue. They bring a new vigour in place of enervation and debility.

Betony, Damiana, Oats, St John’s Wort, Skullcap, Vervain.

Combination. Tea: Equal parts, Skullcap, Betony, Vervain. 1 heaped teaspoon to each cup boiling water; infuse 15 minutes. Half-1 cup freely. ... nerve tonics

Nettlerash

Hives. A rash resembling the sting of a nettle. Itchy red or red-white patches appear chiefly on face and trunk. A transient eruption or watery swelling may appear by release of histamine due to allergy. May be a reaction to environmental irritants from plants, insect stings, chemicals or certain foods as after eating strawberries, lobster. Numerous allergens include food additives, acid fruits, pork, bacon, ham, eggs.

Alte rnative s. Oral anti-histamines include: Burdock, Goldenseal, Juniper berries, Marshmallow, Lobelia, Myrrh, Echinacea, Nettles, Parsley root.

Teas. Betony, Boneset, Celery seed, Chamomile, Chickweed, Elderflowers, Hops, Meadowsweet, Motherwort, Red Clover, Sarsaparilla, Skullcap, Yarrow.

Tea, formula. Equal parts: Meadowsweet, Nettles, Red Clover. 1 heaped teaspoon to each cup boiling water; infuse 15 minutes; 1 cup thrice daily.

Decoction (cold). One teaspoon Barberry bark to each cup cold water steeped overnight. Half-1 cup thrice the following day.

Tablets/capsules. Blue Flag. Echinacea.

Formula. Echinacea 2; Blue Flag 1; Valerian 1. Dose – Powders: 500mg (two 00 capsules or one-third teaspoon). Liquid extracts: 1 teaspoon. Tinctures: 2 teaspoons. Thrice daily.

Practitioner’s prescription. Tinctures: Echinacea ang. 20ml; Ephedra sinica, 20ml; Urtica dioica, 10ml.

Aqua et 100ml. Sig: 5ml (3i) tds Aq cal. pc.

Alternative:– Liquid extract Echinacea ang. 1 fl oz (30ml). Liquid extract Urtica dioica. 1 fl oz. Liquid extract Humulus lupulus. Half fl oz (15ml). Syrup Senna. 2 fl oz (60ml). Aqua et 8 fl oz (240ml). Sig: 8ml (3i) tds aq cal. pc. (Arthur Barker, FNIMH)

Topical. Wash with infusion of Chickweed, Elderflowers, Mullein, Chamomile or Eucalyptus leaves.

Oil of Evening Primrose. Aloe Vera gel.

Creams: Vitamin E, Chickweed, Elderflowers, Comfrey, Plantain. Diet. See: DIET – SKIN DISEASES.

Supplements. Daily. Vitamin A (7500iu). Vitamin C (2g). ... nettlerash

Nettles

Urtica dioica L. German: Grosse Brandnetel. French: Grande ortie. Spanish: Ortiga. Italian: Grande ortica. Part used: dried herb.

Constituents: Chlorophyll (high), vitamins including Vitamin C, serotonin, histamine, acetyl-choline, minerals including iron, calcium, silica.

Action: blood tonic, hypoglycaemic, antiseptic, tonic-astringent (external), diuretic, haemostatic (external), expectorant, vasodilator, hypotensive, galactagogue, splenic, circulatory stimulant, amphoteric (can increase or reduce flow of breast milk, making its own adjustment). Strengthens natural resistance. Re-mineraliser, antirheumatic. Eliminates uric acid from the body. Anti-haemorrhagic. Mild diuretic. Uses: iron-deficiency anaemia, gout (acute painful joints – partial amelioration). First stage of fevers (repeat frequently), malaria. Uvula – inflammation of. Foul-smelling sores. To stimulate kidneys. Detoxifies the blood. Pregnancy (Nettle and Raspberry leaf tea for iron and calcium). To withstand onset of uraemia in kidney disease; chronic skin disease, melaena with blood in stool, splenic disorders, high blood sugar in diabetes, burns (first degree), feeble digestion due to low level HCL; bleeding of stomach, bowels, lung and womb. Has power to eliminate urates; expulsion of gravel. On taking Nettle tea for high blood pressure passage of gravel is possible and should be regarded as a favourable sign. For women desiring an ample bust. Lobster and other shell-fish allergy, strawberry allergy. Nettle rash. Hair – fall out – tea used as a rinse.

“No plant is more useful in domestic medicine.” (Hilda Leyel)

Frequent drinks of Nettle tea often allay itching of Hodgkin’s disease. Preparations. Thrice daily.

Tea: 1oz herb to 1 pint boiling water; infuse 15 minutes. 1 cup.

Liquid Extract: 3-4ml in water.

Tincture BHP (1983): 1 part to 5 parts 45 per cent alcohol. Dose, 2-6ml in water. Powder: 210mg capsules, 6-8 capsules daily. (Arkocaps)

Floradix Herbal Iron Extract contains Nettles. (Salus-Haus)

Nettle shampoo and hair lotion.

Diet. Nettles cooked and eaten as spinach. Fresh juice: 1-2 teaspoons. ... nettles

Neuralgia, Facial

 Trigeminal Neuralgia. Severe lancing pain along one or more branches of the fifth cranial nerve.

Causes include: dental problems, ill-fitting dentures, laughing, yawning, bad teeth.

Symptoms: nervous exhaustion, contracted pupils, flushed face.

Alternatives. Black Cohosh, Cactus, Celery seed, Bogbean, Chamomile, Lady’s Slipper, Ginseng, Hops, Jamaica Dogwood, White Willow, Wild Lettuce, Skullcap, St John’s Wort, Valerian.

Tea. Combine equal parts: Chamomile, Hops, Skullcap. 1 heaped teaspoon to each cup boiling water; infuse 5-10 minutes. 1 cup freely.

Decoction. Combine: Rosemary 2; Ladyslipper 1; Jamaica Dogwood 1.1 heaped teaspoon to each cup water gently simmered 20 minutes. Half-1 cup every 2-3 hours.

Tablets. Passion flower. Ginseng. St John’s Wort, White Willow.

Formula. Equal parts: Jamaica Dogwood, Wild Lettuce, Valerian. Dose: Liquid extracts: 1 teaspoon. Tinctures: 2 teaspoons. Powders: 500mg (two 00 capsules or one-third teaspoon). Thrice daily.

Cayenne pepper (Capsicum). Frequently successful.

Practitioner. Tincture Gelsemium BPC (1973). Dose: 0.3ml (5 drops).

Topical. Poultice: Chamomile, Hops, Linseed or Bran. Acute cases (cold), chronic cases (hot). Grated or bruised Horseradish root. Evening Primrose oil. Hot cider vinegar. Tincture Arnica or Hypericum. Aromatherapy. 2 drops each: Juniper, Lavender, Chamomile to 2 teaspoons vegetable oil. Light massage. Diet, and supplements. Same as for general neuralgia. Australian researchers found that hot curries and spices actually trigger the trigeminal nerve causing a burning sensation. ... neuralgia, facial

Compensation Neurosis

A supposed psychological reaction to injury affected by the prospect of financial compensation. In some cases, the condition may delay physical recovery.... compensation neurosis

Neuralgia, General

 Pain along a nerve, i.e. pain in the shoulders from pressure on a spinal nerve serving the neck.

Alternatives. Black Cohosh, Cactus, Chamomile, Lady’s Slipper, Ginseng, Hops, Jamaica Dogwood, White Willow, Wild Lettuce, Valerian.

Chamomile tea (mild analgesic).

Tablets/capsules. Any of the above.

Formula. Ginseng 4; Black Cohosh 2; Skullcap 2; Mistletoe 1; Motherwort 1. Dose: Liquid Extracts: 1 teaspoon. Tinctures: 2 teaspoons. Powders: 500mg (two 00 capsules or one-third teaspoon). Thrice daily. Children: see: DOSAGE. Cayenne pepper (Capsicum) sometimes successful.

Topical. Poultice: Chamomile, Hops, Linseed or Bran. Acute cases (cold), chronic cases (hot). Grated or bruised Horseradish root. Evening Primrose oil. Hot Cider vinegar, Tincture Arnica or Hypericum. Aromatherapy. 2 drops each: Juniper, Lavender, Chamomile to 2 teaspoons vegetable oil. Light massage. Diet. High protein. Calcium-rich foods.

Supplements. Vitamin B-complex, B6, B12, Niacin, Magnesium, Dolomite, Zinc.

See: FACIAL and INTERCOSTAL NEURALGIA; DYSMENORRHOEA (neuralgia of the womb). ANTISPASMODICS. ... neuralgia, general

Neuralgia, Intercostal

 Pain along a sensory nerve serving the chest, without loss of sensation and power of movement. Differs from neuritis in which nerves are inflamed.

Causes: all kinds of infective diseases. Rheumatism, bad teeth, bony spinal lesions, gall stone, liver disorder, thickening of pleura, fractured ribs, shingles – see: SHINGLES. In simple cases a cup of Chamomile tea may suffice. Persistent cases require one of the following alternatives.

Alternatives. Decoction. Combine equal parts: Black Cohosh, Jamaica Dogwood (or White Willow), Pleurisy root. 1 heaped teaspoon to each cup water gently simmered 20 minutes. Half-1 cup thrice daily. Formula. Cramp bark 2; Black Cohosh 1; Valerian 1. Pinch of Cayenne or few drops Tincture Capsicum. Dose: Liquid Extracts: 1 teaspoon. Tinctures: 2 teaspoons. Powders: 500mg (two 00 capsules or one- third teaspoon). Thrice daily.

Neuralgia associated with bronchi and lung: Formula: Cramp bark 2; Pleurisy root 2; Liquorice half. Dose: as above.

Practitioner. Tincture Gelsemium BPC (1973). 0.3ml (5 drops) in water as necessary.

Dr Finlay Ellingwood. Tincture Pleurisy root (Asclepias). 20 drops, every 2 hours.

Topical. Poultice: Chamomile, Hops, Linseed or Bran. Acute cases (cold), chronic cases (hot). Grated or bruised Horseradish root. Evening Primrose oil. Hot Cider vinegar. Tincture Arnica or Hypericum. Aromatherapy. 2 drops each: Juniper, Lavender, Chamomile, to 2 teaspoons vegetable oil. Massage. Diet, vitamins, minerals. Same as for general neuralgia. Cold water packs. ... neuralgia, intercostal

Jaundice, Neonatal

Yellowing of the skin and whites of the eyes in newborn babies, due to accumulation of bilirubin in the blood. It usually results from the liver being immature and unable to excrete bilirubin efficiently. This form of jaundice is usually harmless and disappears within a week. Rarely, severe or persistent neonatal jaundice is caused by haemolytic disease of the newborn, G6PD deficiency, hepatitis, hypothyroidism, biliary atresia, or infection.

Jaundiced babies usually require extra fluids and may be treated with phototherapy.

Exchange transfusion (see blood transfusion) may be needed in severe cases.

If severe neonatal jaundice is not treated promptly, kernicterus may occur.... jaundice, neonatal

Laryngeal Nerve

One of a pair of nerves that carry instructions from the brain to the larynx and send sensations from the larynx to the brain.... laryngeal nerve

Median Nerve

One of the main nerves of the arm. It is a branch of the brachial plexus and runs down the arm from the shoulder into the hand. The median nerve controls the muscles that carry out bending movements of the wrist, fingers, and thumb, and that rotate the forearm palm-inwards. The nerve also conveys sensations from the thumb and first 3 fingers, and from the region of the palm at their base.

Damage to the nerve may result from injury to the shoulder, a Colles’ fracture just above the wrist, or pressure on the nerve where it passes through the wrist (carpal tunnel syndrome).

Symptoms of damage include numbness and weakness in areas controlled by the nerve.... median nerve

Neck Dissection, Radical

A surgical procedure for the removal of cancerous lymph nodes in the neck.

The operation is commonly part of the treatment of cancer of the tongue, tonsils, or other structures in the mouth and throat.... neck dissection, radical

Neck Rigidity

Marked stiffness of the neck caused by spasm of the muscles in the neck and spine.

Neck rigidity is an important clinical sign of meningitis (inflammation of the membranes covering the brain and spinal cord).

Severe neck rigidity may cause the head to arch backwards, especially in babies.... neck rigidity

Necrolysis, Toxic Epidermal

A severe, blistering rash in which the surface layers of the skin peel off, exposing large areas of red raw skin over the body. The condition carries a risk of widespread infection and loss of body fluid and salts.

The most common cause of toxic epidermal necrolysis is an adverse reaction to a drug, particularly a barbiturate, sulphonamide, or penicillin. The condition usually clears up when the drug is discontinued. Intravenous fluid replacement is sometimes necessary.... necrolysis, toxic epidermal

Necrophilia

A rare sexual perversion in which orgasm is achieved by means of sexual acts with dead bodies.... necrophilia

Needle Aspiration

See biopsy.... needle aspiration

Needle Exchange

A health scheme that enables intravenous drug abusers to exchange used hypodermic needles for new, sterile ones.

The scheme is aimed at reducing the risks of infections, such as HIV and hepatitis, transmitted by the sharing of contaminated needles.... needle exchange

Needlestick Injury

Accidental puncture of the skin by a contaminated hypodermic needle. Hospital staff are most likely to be at risk. Needlestick injuries carry the risk of serious infections, such as HIV and hepatitis, and need immediate attention. The wound should be cleaned thoroughly; blood tests may be needed to determine whether infection has been transmitted.... needlestick injury

Nefopam

An analgesic drug used to relieve moderate pain caused, for example, by injury, surgery, or cancer.

Possible adverse effects include nausea, nervousness, dry mouth, and difficulty sleeping.... nefopam

Nervous Energy

A nontechnical term for the increased drive and activity of individuals who are always restless, anxious, and on the go.... nervous energy

Nervous Habit

A nontechnical term for a minor repetitive movement or activity. Sometimes a nervous habit consists of involuntary twitches and facial tics, such as in Gilles de la Tourette’s syndrome and some forms of dyskinesia. Voluntary nervous habits, such as nailbiting and thumb-sucking, are common in young children.

All nervous habits increase during periods of tension or anxiety, and may be severe in some forms of depression, anxiety disorder, or drug withdrawal.... nervous habit

Nerve Conduction Studies

Tests carried out to assess the extent of nerve damage caused by disorders of the peripheral nervous system (see neuropathy). In the test, an electrical stimulus is applied to a nerve, and the speed at which the nerve responds to the stimulus and transmits a signal is recorded.

nerve injury Damage or severance of conducting fibres within a nerve as a result of trauma, causing loss of skin sensation and muscle power. (See neuropathy for nerve damage from cause.

other than injury.)

If a peripheral nerve (a nerve outside the brain or spinal cord) is only partially severed, the cut fibres may be able to regenerate. Provided the severed ends are still aligned, new fibres can grow across the cut to rejoin the connection, restoring function. If a nerve is totally severed, the individual fibres cannot regenerate successfully and there is no recovery of function. Nerve tracts within the brain and spinal cord are structurally different from the peripheral nerves, and severed fibres in these tracts do not regenerate. For example, vision cannot be restored if the optic nerves are cut.Microsurgery can sometimes be used to stitch a severed peripheral nerve into place, but recovery is rarely complete.... nerve conduction studies

Nerve, Trapped

Compression or stretching of a nerve, causing numbness, tingling, weakness, and, sometimes, pain. Common examples of a trapped nerve include carpal tunnel syndrome, in which pressure on the median nerve as it passes through the wrist causes symptoms in the thumb, index, and middle fingers; a disc prolapse, in which pressure on the nerve root leading from the spinal cord produces symptoms in the back and legs; and crutch palsy, in which the radial nerve presses against the humerus (upper-arm bone), producing symptoms in the wrist and hand.

A damaged nerve may take some time to heal. In severe cases, surgical decompression to relieve pressure on the nerve may be necessary.... nerve, trapped

Netilmicin

An antibiotic drug usually prescribed only to treat serious infection in hospital, when other antibiotic drugs have proved ineffective. In rare circumstances, netilmicin can damage the inner ear or the kidneys.... netilmicin

Neural Tube Defect

A developmental failure affecting the spinal cord or brain of the embryo. The most serious defect is anencephaly (total lack of a brain), which is fatal. More common is spina bifida, in which the vertebrae do not form a complete ring around the spinal cord. Spina bifida can occur anywhere on the spine, but it is most common in the lower back.

There are different forms of spina bifida. In spina bifida occulta, the only defect is a failure of the fusion of the bony arches behind the spinal cord, which may not cause any problems. When the bone defect is more extensive, there may be a meningocele, a protrusion of the meninges, or a myelomeningocele, a malformation of the spinal cord. Myelomeningocele is likely to cause severe handicap, with paralysis of the legs, loss of sensation in the lower body, hydrocephalus, and paralysis of the anus and bladder, causing incontinence. Associated problems include cerebral palsy, epilepsy, and mental handicap.

Surgery is usually performed a few days after birth. In mild cases, the defect can usually be corrected, but in myelomeningocele, some handicap will remain.

Genetic factors play a part in neural tube defects, which show multifactorial inheritance. Couples who have had an affected child or who have a family history of neural tube defects should seek genetic counselling. The risk of a neural tube defect occurring can be substantially reduced if the mother takes folic acid supplements for a month before conception and during the early part of the pregnancy.

Ultrasound scanning and amniocentesis allow accurate antenatal testing for neural tube defects.... neural tube defect

Neurocutaneous Disorders

A group of conditions characterized by abnormalities of the skin and of the nerves and/or the central nervous system.

The best known of these neurocutaneous disorders is neurofibromatosis, in which there are brown patches on the skin and numerous fibrous nodules on the skin and nerves. Another example is tuberous sclerosis, which is characterized by small skin-coloured swellings over the cheeks and nose, mental deficiency, and epilepsy.... neurocutaneous disorders

Neuroendocrinology

The study of the interactions between the nervous system and the endocrine system that control internal body functions and the body’s response to the external environment.... neuroendocrinology

Newborn

An infant at birth and during the 1st few weeks of life (see also prematurity; postmaturity).... newborn

Neuropathic Joint

A joint that has been damaged by inflammation and a series of injuries, which pass unnoticed due to loss of sensation in the joint resulting from neuropathy (nerve damage caused by disease). Neuropathic joints develop in a number of conditions, including diabetes mellitus and untreated syphilis.

When sensation to pain is lost, abnormal stress and strain on a joint do not stimulate the protective reflex spasm of the surrounding muscles; this failure of the protective reflex allows exaggerated movement that can damage the joint. Osteoarthritis, swelling, and deformity are features of a neuropathic joint.An orthopaedic brace or caliper splint may be necessary to restrict any abnormal movement of the joint.

Occasionally, an arthrodesis (a surgical operation to fuse a joint) is performed.

The nerve damage is irreversible.... neuropathic joint

Postherpetic Neuralgia

Burning pain caused by nerve irritation that occurs at the site of a previous attack of herpes zoster (shingles).

See neuralgia.... postherpetic neuralgia

Stiff Neck

A common symptom, usually due to spasm in muscles at the side or back of the neck. In most cases, it occurs suddenly and for no apparent reason. It may result from a neck injury, such as a ligament sprain, disc prolapse, or whiplash injury. A rare cause is meningitis.

Mild stiffness may be relieved by massage, warming, and use of a liniment. Severe or persistent stiffness requires medical attention. (See also torticollis.)... stiff neck

Trapped Nerve

See nerve, trapped.... trapped nerve

Urticaria, Neonatal

A very common, harmless skin condition, also known as erythema neonatorum or toxic erythema, that affects newborn infants. A blotchy rash, in which raised white or yellow lumps are surrounded by illdefined red areas of inflammation, forms, mainly affecting the face, chest, arms, and thighs. The cause of neonatal urticaria is unknown. The rash usually clears up without treatment.... urticaria, neonatal

Abducens Nerve

the sixth *cranial nerve (VI), which supplies the lateral rectus muscle of each eyeball, responsible for turning the eye outwards.... abducens nerve

Academic Health Science Network

(AHSN, academic health science centre, academic health science system, academic medical partnership) a regional partnership between one or more academic institutions (typically universities) and one or more health-care providers (in England, typically foundation trusts) with a twin focus on promoting economic growth in the region covered and improving the health of the population. Many AHSNs also include third-sector and industry partners and most have a role in providing education and training. The fifteen AHSNs across England were established by NHS England in 2013 and represent a national expansion of the earlier Academic Health Science Partnerships (AHSPs), which were first set up in London in 2007.... academic health science network

Acute Retinal Necrosis

(ARN) severe inflammation and necrosis of the retina associated with inflammation and blockage of retinal blood vessels, haemorrhage and death of retinal tissue, and retinal detachment. It may affect both eyes (bilateral acute retinal necrosis, BARN), and visual prognosis is poor. ARN is thought to be due to viral infection.... acute retinal necrosis

Acute Tubular Necrosis

(ATN) a condition caused by acute renal injury from either ischaemia or toxins and associated with tubular damage that is usually reversible. The earliest feature is *isosthenuria, which may occur while there is still a high urine flow rate. This is followed by a reduction in *glomerular filtration rate. *Oliguria is common and dialysis often needed for survival. If the cause of the initial damage can be removed, recovery of renal function within six weeks can be expected in most cases.... acute tubular necrosis

Analgesic Nephropathy

n. disease of the *tubulointerstitium of the kidney associated with chronic use of mixed analgesic preparations. Phenacetin, paracetamol, and salicylates have all been implicated. The condition is progressive and results in bilateral atrophy of the kidneys and chronic renal failure. In the early stages the condition is asymptomatic. The earliest clinical manifestations relate to disordered tubular function with impaired concentration and acidification of the urine.... analgesic nephropathy

Asymmetric Tonic Neck Reflex

a primitive reflex that is present from birth but should disappear by six months of age. If the infant is lying on its back and the head is turned to one side, the arm and leg on the side to which the head is turned should straighten, and the arm and leg on the opposite side should bend (the ‘fencer’ position). Persistence of the reflex beyond six months is suggestive of *cerebral palsy.... asymmetric tonic neck reflex

Auditory Neuropathy Spectrum Disorder

(auditory neuropathy, auditory dyssynchrony) a form of hearing loss characterized by normal cochlear function as measured by *otoacoustic emissions or detection of *cochlear microphonics but abnormal or absent *middle ear reflexes and abnormal *auditory brainstem responses.... auditory neuropathy spectrum disorder

Balkan Nephropathy

a severe and progressive form of tubulointerstitial renal disease (see tubulointerstitium), first described in 1956 and endemic to certain rural areas along the tributaries of the Danube in Bosnia, Bulgaria, Croatia, Romania, and Serbia. The natural course of the disease is progression to end-stage kidney failure and frequent development of tumours in the upper urinary tract. It seems likely that an environmental factor is responsible for the disease, and evidence supports the theory that long-term consumption of food contaminated with seeds from plants of *Aristolochia spp. underlies the pathogenesis.... balkan nephropathy

Berger’s Nephropathy

(IgA nephropathy) an abnormality of the kidney in which there is a focal area of inflammation (*glomerulonephritis). This causes microscopic amounts of blood in the urine. A quarter of the patients with this condition may develop kidney failure. [J. Berger (20th century), French nephrologist]... berger’s nephropathy

Bladder Neck Incision

an operation that involves an incision through the bladder neck that is extended into the prostate to relieve *lower urinary tract symptoms. This procedure is usually performed under a general or spinal anaesthetic through a cystoscope. It is not as extensive as a transurethral resection of the prostate and is therefore associated with a comparatively lower incidence of side-effects.... bladder neck incision

Cast Nephropathy

(myeloma kidney) a complication of multiple myeloma seen in approximately half of those who have renal disease. The casts typically involve the distal convoluted and collecting tubules and often have a fractured or crystalline appearance. They are frequently surrounded by multinucleate giant cells. Deposition of the casts is associated with progressive renal failure.... cast nephropathy

Chinese Herb Nephropathy

a condition that came to prominence in the 1990s when hundreds of young European women developed end-stage renal disease after receiving slimming pills containing Chinese herbs. The condition is also associated with a high incidence of urothelial tumours. It was eventually proved that the product was contaminated with aristolochic acid, a main toxic product of *Aristolochia plant species. Its presence in the slimming regimen was the result of accidental substitution of the prescribed herb Stephania tetrandra (han fang-ji) by A. fangchi (guang fang-ji).... chinese herb nephropathy

Circumflex Nerve

a mixed sensory and motor nerve of the upper arm. It arises from the fifth and sixth cervical segments of the spinal cord and is distributed to the deltoid muscle of the shoulder and the overlying skin.... circumflex nerve

Cochlear Nerve

(acoustic nerve, auditory nerve) the nerve connecting the cochlea to the brain and therefore responsible for transmitting the nerve impulses relating to hearing. It forms part of the *vestibulocochlear nerve (cranial nerve VIII).... cochlear nerve

Contrast Nephropathy

deterioration in renal function (of more than 25%) after administration of radiocontrast material. Development of this condition is more likely when there is pre-existing renal disease (the most important factor) or diabetes, vasoconstriction, simultaneous use of NSAIDs, and large amounts of radiocontrast are used. It is thought that the radiocontrast induces vasoconstriction in the vessels supplying the medulla of the kidney and aggravates hypoxia in this part of the kidney.... contrast nephropathy

Dental Nerve

either of two nerves that supply the teeth; they are branches of the trigeminal nerve. The inferior dental nerve supplies the lower teeth and for most of its length exists as a single large bundle; thus anaesthesia of it has a widespread effect (see inferior dental block). The superior dental nerve, which supplies the upper teeth, breaks into separate branches at some distance from the teeth and it is possible to anaesthetize these individually with less widespread effect for the patient.... dental nerve

Diabetic Nephropathy

progressive damage to the kidneys seen in some people with long-standing diabetes. Excessive leakage of protein into the urine is followed by gradual decline of the kidney function and even kidney failure. See also diabetic glomerulosclerosis.... diabetic nephropathy

Diabetic Neuropathy

progressive damage to the peripheral nerves seen in some people with long-standing diabetes. It most commonly affects the legs, causing pain or numbness working up from the feet. There is no cure but drugs can sometimes be used to control the discomfort experienced, and good blood glucose control may prevent deterioration over time. See also diabetic holiday foot syndrome.... diabetic neuropathy

Early Neonatal Death

see perinatal mortality rate.... early neonatal death

Fine-needle Aspiration Cytology

(FNA cytology) a technique in which a thin hollow needle is inserted into a mass to extract a tissue sample for microscopic examination. It is useful for detecting the presence of malignant cells, particularly in lumps of the breast and thyroid. See also aspiration cytology.... fine-needle aspiration cytology

Gestational Trophoblastic Neoplasia

(GTN) a group of disorders characterized by persistence of *gestational trophoblastic disease, with abnormal placental development and very high levels of *human chorionic gonadotrophin (hCG). The chorionic villi are fluid-filled with vacuolation of the placenta and destruction of the normal stroma. GTN is rare in the UK, with a calculated incidence of 1/714 live births. It may develop after a molar pregnancy (see hydatidiform mole), a nonmolar pregnancy, or a live birth. The incidence after a live birth is estimated at 1/50,000. A malignant condition may develop (see choriocarcinoma) if the abnormal tissue is not completely removed and the risk of this is monitored by the fall in hCG levels. Choriocarcinoma complicates approximately 3% of complete moles, although in 50% of cases of choriocarcinoma there is no history of immediately preceding trophoblastic disease. It may also occur following a normal pregnancy. In the UK, there is an effective registration and treatment programme. The programme has achieved impressive results, with high cure (98–100%) and low chemotherapy (5–8%) rates.... gestational trophoblastic neoplasia

Haemorrhagic Disease Of The Newborn

a temporary disturbance in blood clotting caused by *vitamin K deficiency and affecting infants on the second to fourth day of life. It varies in severity from mild gastrointestinal bleeding to profuse bleeding into many organs, including the brain. It is more common in breast-fed and preterm infants. The condition can be prevented by giving all babies vitamin K, either by injection or orally, shortly after birth. Medical name: melaena neonatorum.... haemorrhagic disease of the newborn

Hemispatial Neglect

(neglect syndrome) a deficit in attention to and awareness of one side of space. It is characterized by inability to process and perceive stimuli on one side of the body or environment that is not due to a lack of sensation. It is generally seen after damage to the right hemisphere, which leads to neglect of the contralateral (left) side of space.... hemispatial neglect

Heroin-associated Nephropathy

see HAN.... heroin-associated nephropathy

House–brackmann Facial Nerve Grading System

(House–Brackmann score, House–Brackmann scale, House–Brackmann facial weakness scale) a six-point grading system for patients with *Bell’s palsy or other forms of facial nerve palsy. Grade I is normal function; grade VI is a total palsy. [J. W. House and D. E. Brackmann (21st century), US otorhinolarygologists]... house–brackmann facial nerve grading system

Hypercalcaemic Nephropathy

defects of kidney function related to a high serum calcium, irrespective of cause. Impaired urine-concentrating ability and reduction in glomerular filtration rate are common features. Histologically, calcific deposits in the kidneys (*nephrocalcinosis) may be seen in cases of long-standing hypercalcaemia.... hypercalcaemic nephropathy

Hypokalaemic Nephropathy

abnormalities seen with chronic hypokalaemia (usually K+ <3.0 mmol/l) and manifest by impaired urine-concentrating ability and reduced capacity to excrete sodium. Histological changes include cytoplasmic vacuolation of the renal tubules and medullary fibrosis.... hypokalaemic nephropathy

Iga Nephropathy

see Berger’s nephropathy.... iga nephropathy

Interstitial Nephritis

disease of the *tubulointerstitium of the kidney. Acute interstitial nephritis (AIN) represents in many cases an allergic reaction to drugs (especially ampicillin, cephalexin, NSAIDs, allopurinol, and frusemide). AIN can also be associated with acute infections and autoimmune disease. Thirst and polyuria may be prominent, and renal function severely affected. In allergic cases, the use of steroids hastens recovery after the allergen has been removed. Chronic interstitial nephritis (CIN) is associated with progressive scarring of the tubulointerstitium, often with lymphocyte infiltration. Primary causes of CIN include gout, radiation nephropathy, sarcoidosis, *analgesic nephropathy, reflux nephropathy, chronic hypokalaemia and hypercalcaemia, and *Aristolochia-associated nephropathies. Management of CIN involves removal of the precipitating cause, where identified, and control of hypertension.... interstitial nephritis

Intraosseous Needle

a wide-bore needle for insertion directly into the bone marrow of (usually) the tibia in children, used only in emergencies when no other means of intravenous access can be gained. Intraosseous needles enable fluids and drugs to be given rapidly. They are only for use with unconscious patients and must be removed when alternative access is obtained.... intraosseous needle

Late Neonatal Death

death of a baby between 7 and 27 completed days of life.... late neonatal death

Local Involvement Networks

(LINks) groups set up to help local people get involved in the development and delivery of health and social care services; they were replaced by local *Healthwatch organizations in 2013.... local involvement networks

Lupus Nephritis

a frequent and serious complication of systemic *lupus erythematosus (SLE). The 2002 WHO/ISN/RPS classification of lupus nephritis recognizes six classes: class I is the presence of mesangial deposits (see juxtaglomerular apparatus) seen on immunofluorescence and/or electron microscopy; class II is the presence of mesangial deposits and mesangial hypercellularity; class III is focal and segmental *glomerulonephritis; class IV is diffuse segmental or global nephritis; class V is *membranous nephropathy; and class VI is advanced sclerotic glomerulonephritis. Untreated, outcomes are poor in classes III and IV, but much improved with immunosuppressant treatment.... lupus nephritis

Medullated Nerve Fibre

(myelinated nerve fibre) see myelin.... medullated nerve fibre

Membranous Nephropathy

a common cause of the *nephrotic syndrome in adults. The diagnosis is established by renal biopsy, which shows diffuse global subepithelial deposits within the glomerulus. Most cases of membranous nephropathy are idiopathic, but there are associations with infection (e.g. hepatitis B), malignancy (especially lung cancer), autoimmune disease (e.g. SLE, Hashimoto’s disease), and drugs (e.g. gold and penicillamine). Recent studies suggest that idiopathic membranous nephropathy is an autoimmune disease with antibodies directed against an antigen (PLA2R, a phospholipase A2 receptor) on the *podocyte cell membrane. Without treatment, outcome is very variable: some patients will make a full recovery, while others will progress to end-stage kidney failure. Immunosuppressant treatment is often tried when there is evidence of declining renal function.... membranous nephropathy

Motor Nerve

one of the nerves that carry impulses outwards from the central nervous system to bring about activity in a muscle or gland. Compare sensory nerve.... motor nerve

Motor Neuron

one of the units (*neurons) that goes to make up the nerve pathway between the brain and an effector organ, such as a skeletal muscle. An upper motor neuron has a cell body in the brain and an axon that extends into the spinal cord, where it ends in synapses. It is thus entirely within the central nervous system. A lower motor neuron, on the other hand, has a cell body in the spinal cord or brainstem and an axon that extends outwards in a cranial or spinal motor nerve to reach an effector.... motor neuron

Multiple Endocrine Neoplasia

(MEN) see MENS.... multiple endocrine neoplasia

Musculocutaneous Nerve

a nerve of the *brachial plexus that supplies some muscles of the arm and the skin of the lateral part of the forearm.... musculocutaneous nerve

Nead

see non-epileptic attack disorde.... nead

Nearthrosis

n. see pseudarthrosis.... nearthrosis

Necator

n. a genus of *hookworms that live in the small intestine. The human hookworm, N. americanus, occurs in tropical Africa, Central and South America, India, and the Pacific Islands. The worm possesses two pairs of sharp cutting plates inside its mouth cavity, which enable it to feed on the blood and tissues of the gut wall. Compare Ancylostoma.... necator

Minimal Change Nephropathy

the commonest cause of *nephrotic syndrome in children and an important cause of this syndrome in adults. The condition is so named because of the apparent lack of abnormalities seen on light microscopy of biopsy samples. Changes can, however, be seen on electron microscopy, with effacement of the *podocyte foot processes along the glomerular basement membrane. It is postulated that minimal change disease is a T-cell disease and that *cytokine damage to the podocytes leads to loss of the selective filtering characteristics of the glomerulus. The condition usually responds to corticosteroids and has a good prognosis, but there is clinical overlap with primary *focal segmental glomerulosclerosis, which may have similar histological appearances in its early stages, tends not to respond to steroids, and is associated with a poor renal prognosis.... minimal change nephropathy

Necatoriasis

n. an infestation of the small intestine by the parasitic hookworm Necator americanus. See also hookworm disease.... necatoriasis

Necessity

n. the ethical and legal doctrine that provides justification for doing something that might otherwise be seen as blameworthy when the consequences of not doing so would be worse. For example, doctors have no right to touch a patient without consent, yet might be considered lacking in duty of care if they did not restrain patients who were about to kill themselves. See also paternalism.... necessity

Necro

combining form denoting death or dissolution.... necro

Necrobiosis

n. a gradual process by which cells lose their function and die. Necrobiosis lipoidica is a disease in which degeneration of collagen produces sharply demarcated yellowish-brown plaques, especially on the shins of women. The association with diabetes mellitus is controversial.... necrobiosis

Necrology

n. the study of the phenomena of death, involving determination of the moment of death and the different changes that occur in the tissues of the body after death.... necrology

Necrospermia

n. the presence of either dead or motionless spermatozoa in the semen. See infertility.... necrospermia

Necrotizing Enterocolitis

(NEC) a serious disease affecting the bowel during the first three weeks of life; it is much more common in preterm babies. The abdomen distends and blood and mucus appear in the stools; the bowel may perforate. Treatment is to rest the bowel and administer antibiotics. If the bowel becomes necrotic, surgery may be necessary. The cause is unknown but the disease may be the result of a reduced supply of oxygen to the bowel or infection.... necrotizing enterocolitis

Nedocromil

n. a drug, related to sodium *cromoglicate, used to prevent asthma attacks and to treat allergic conjunctivitis. Possible side-effects include local irritation.... nedocromil

Needle

n. a slender sharp-pointed instrument used for a variety of purposes. The size and shape of needles used in surgery for stitching tissue depend on the type of surgery. Most surgical needles have suture material fused onto them (so-called atraumatic needles). Hollow needles are used to inject substances into the body (in hypodermic syringes), to obtain specimens of tissue (see puncture), or to withdraw fluid from a cavity (see aspiration; biopsy). See also stop needle.... needle

Negative Feedback Loop

a physiological loop for the control of hormone production by a gland. High levels of a circulating hormone act to reduce production of the releasing factors triggering its own production, i.e. they have a negative *feedback on these trigger factors. As circulating levels of the hormone fall, the negative feedback is reduced and the releasing factor starts to be produced again, allowing the hormone level to rise again.... negative feedback loop

Negative Symptoms

(in psychiatry) symptoms of schizophrenia characterized by a deficiency in or absence of some aspect of functioning, such as social withdrawal, loss of initiative, and blunted affect. Compare positive symptoms.... negative symptoms

Neglect Syndrome

see hemispatial neglect.... neglect syndrome

Neisseria

n. a genus of spherical Gram-negative aerobic nonmotile bacteria characteristically grouped in pairs. They are parasites of animals, and some species are normal inhabitants of the human respiratory tract. The species N. gonorrhoeae (the gonococcus) causes *gonorrhoea. Gonococci are found within pus cells of urethral and vaginal discharge; they can be cultured only on serum or blood agar. N. meningitidis (the meningococcus) causes meningococcal *meningitis. Meningococci are found within pus cells of infected cerebrospinal fluid and blood or in the nasal passages of carriers. They too can only be cultured on serum or blood agar.... neisseria

Nemosis

n. the activation of normal fibroblasts that occurs if they cluster and make cell-to-cell contact. This induces the production of *chemokines, *growth factors, enzymes, etc., which can influence cancer cells and inflammation. It leads to programmed cell death (see apoptosis).... nemosis

Neoadjuvant Chemotherapy

chemotherapy that is given before the (usually) surgical treatment of a primary tumour with the aim of shrinking the tumour and therefore improving the results of surgery or radiotherapy and preventing the development of metastases. Compare adjuvant therapy.... neoadjuvant chemotherapy

Neglected Tropical Diseases

(NTDs) as defined by the *World Health Organization (WHO), a diverse group of *communicable diseases found almost entirely among poor populations in tropical and subtropical parts of Africa, Asia, and the Americas. Although they affect more than 1.4 billion people, and countermeasures would in many cases be inexpensive, NTDs have traditionally received far less attention than the major infectious diseases HIV/AIDS, tuberculosis, and malaria. In 2013 the WHO resolved to intensify its efforts to eradicate or control NTDs. The current WHO list identifies 24 such diseases, including *Buruli ulcer, *chikungunya fever, *dengue, *leishmaniasis, and *Madura foot (mycetoma).... neglected tropical diseases

Neocerebellum

n. the middle lobe of the *cerebellum, excluding the pyramid and uvula. In evolutionary terms it is the newest part, occurring only in mammals.... neocerebellum

Neointimal Hyperplasia

a pathological process involved in *atherosclerosis of arteries and vein grafts, and in *restenosis, that may be in response to angioplasty and stent placement. Damage to the endothelium of the artery exposes the underlying smooth muscle cells in the *media to cytokines, growth factors, and other plasma components in the circulation, which results in loss of their contractile characteristics. These abnormal muscle cells migrate to the *intima, where they proliferate and eventually form a thick layer of tissue (neointima), which occludes the artery.... neointimal hyperplasia

Neonatal Abstinence Syndrome

(NAS) symptoms and signs exhibited by a newborn baby (neonate) due to drug withdrawal (see dependence). This results when the fetus has been exposed to addictive drugs through maternal substance abuse or misuse. Symptoms tend to occur in the first few days of life (in the case of methadone, which is a long-acting opioid, symptom onset may be delayed). They include tremors and jerking, high-pitched crying, sneezing, sucking of fists, feeding difficulties, shortened periods of sleep between feeds, rapid breathing, sweating, loose stools, nasal stuffiness, and frequent yawning. Treatment includes swaddling or snugly wrapping in a blanket, as babies with NAS are often difficult to comfort. Other nonpharmacological measures include frequent small feeds using high-calorie formula and intravenous fluids if babies become dehydrated. Drug therapy may be used for seizures and withdrawal symptoms.... neonatal abstinence syndrome

Neonatal Early Warning Score

an assessment tool for newborn babies, consisting of a chart in which a combination of *vital signs, neurological involvement, observation of blue skin and lips, and level of behavioural response indicate the appropriate level of concern. It is colour-coordinated from red to green to enable standardized escalation of concerns about the sick baby.... neonatal early warning score

Neonatal Mortality Rate

see infant mortality rate.... neonatal mortality rate

Neonatal Screening

*screening tests carried out on newborn babies to detect diseases that appear in the neonatal period, such as phenylketonuria (see Guthrie test). If these diseases are detected early enough, treatment may be instigated before any irreversible damage occurs to the baby.... neonatal screening

Neonatal Teeth

teeth that emerge through the gingiva (gums) during the first month of life.... neonatal teeth

Neonatal Urticaria

see erythema.... neonatal urticaria

Neopallium

n. an enlargement of the wall of each cerebral hemisphere. In evolutionary terms it is the newest part of the cerebrum, formed by the development of new pathways for sight and hearing in mammals.... neopallium

Neosphincter

n. a substituted muscle or an implant for an absent or ineffective sphincter (see artificial sphincter).... neosphincter

Neovascularization

n. the abnormal formation of new and fragile blood vessels, usually in response to ischaemia. In choroidal neovascularization, which occurs in such conditions as *macular degeneration, abnormal vessels, derived from the *choroid, form in the space between the retinal pigment epithelium (RPE) and the choroid (see retina).... neovascularization

Nephr

(nephro-) combining form denoting the kidney(s).... nephr

Nephrin

n. a transmembrane protein localized to the slit diaphragm of the *podocyte and necessary for the proper functioning of the renal filtration barrier. The latter consists of fenestrated endothelial cells, the basement membrane, and the epithelial podocyte. A defect in the gene coding for nephrin (NPHS1) on chromosome 19 results in congenital nephrotic syndrome of Finnish type (which is not exclusive to the Finnish population).... nephrin

Nephritic Syndrome

generalized inflammation of the glomeruli of the kidneys resulting in a reduction in *glomerular filtration rate, with mild oedema and hypertension resulting from renal salt and water retention. Urine analysis shows the presence of proteinuria and microscopic haematuria with red cell casts. Common and usually self-limiting causes are *Berger’s nephropathy and poststreptococcal glomerulonephritis. Less common but more serious causes of the nephritic syndrome are the vasculitides (see vasculitis) and *Goodpasture’s disease, which, untreated, usually prove fatal.... nephritic syndrome

Nephrogenic Cord

either of the paired ridges of tissue that run along the dorsal surface of the abdominal cavity of the embryo. Parts of it develop into the kidney, ovary, or testis and their associated ducts. Intermediate stages of these developments are the *pronephros, *mesonephros, and *metanephros.... nephrogenic cord

Nephrogenic Diabetes Insipidus

(NDI) a condition characterized by *polyuria and *polydipsia and due to failure of the renal tubules to respond, or to respond fully, to *vasopressin. One form of congenital NDI is caused by an X-linked (see sex-linked) dominant mutation of the gene encoding the vasopressin V2 receptor. A rarer form of congenital NDI is an autosomal recessive condition associated with genetic mutations in the gene encoding AQP-2 water channels (see aquaporin). Acquired NDI is much commoner than the congenital form and usually less severe. It is present in most patients with advancing chronic renal failure, is a feature of certain electrolyte disorders (hypokalaemia, hypercalcaemia), and can complicate chronic lithium treatment.... nephrogenic diabetes insipidus

Nephrogenic Systemic Fibrosis

(NSF, nephrogenic fibrosing dermopathy) a rare condition, first reported in 1997, that occurs exclusively in patients with chronic kidney disease (CKD), who develop large areas of hardened skin with fibrotic nodules and plaques. Flexion contractures with an accompanying limitation of range of motion can also occur. Exposure to gadolinium, used as a contrast agent in magnetic resonance imaging, has been identified as a causative factor, but many patients with severe CKD have been exposed to gadolinium without consequence. Linear gadolinium preparations (Omniscan, OptiMARK) appear to carry the highest risk of NSF. There is no cure for the condition.... nephrogenic systemic fibrosis

Nephroscopy

n. inspection of the interior of the kidney with a *nephroscope.... nephroscopy

Nephrostogram

n. X-ray imaging (see fluoroscopy) of the interior of the kidney and ureter after injecting a radiographic *contrast medium through a catheter placed inside the renal pelvis (see nephrostomy). This procedure is done to check for any problems with the drainage of urine from the pelvis to the ureter.... nephrostogram

Nephrotoxic

adj. liable to cause damage to the kidneys. Nephrotoxic drugs include *aminoglycoside antibiotics, sulphonamides, and gold compounds. —nephrotoxicity n.... nephrotoxic

Nephroureterectomy

(ureteronephrectomy) n. the surgical removal of a kidney together with its ureter. This operation is performed for cancer of the kidney pelvis or ureter. It is also undertaken when the kidney has been destroyed by *vesicoureteric reflux, to prevent subsequent continuing reflux into the stump of the ureter that would occur if only the kidney were removed.... nephroureterectomy

Nerve Conduction Study

a test done to assess the peripheral nervous system. It involves activating the nerves electronically with electrical pulses and measuring the responses obtained.... nerve conduction study

Nerve Ending

the final part (terminal) of one of the branches of a nerve fibre, where a *neuron makes contact either with another neuron at a synapse or with a muscle or gland cell at a neuromuscular or neuroglandular junction.... nerve ending

Nerve Entrapment Syndrome

any syndrome resulting from pressure on a nerve from surrounding structures. Examples include the *carpal tunnel syndrome and *meralgia paraesthetica.... nerve entrapment syndrome

Nerve Fibre

the long fine process that extends from the cell body of a *neuron and carries nerve impulses. Bundles of nerve fibres running together form a *nerve. Each fibre has a sheath, which in medullated nerve fibres is a relatively thick layer containing the fatty insulating material *myelin.... nerve fibre

Nerve Gas

any gas that disrupts the normal functioning of nerves and thus of the muscles they supply. There are two groups, the G agents and the V agents. The latter are more than 300 times as deadly as mustard gas: one inhalation can kill by paralysing the respiratory muscles. V agents also act through the skin, therefore gas masks are ineffective protection against them.... nerve gas

Nerve Growth Factor

(NGF) a protein (see growth factor), consisting of two polypeptide chains, that is required for the development and longevity of some neurons, including those in the sympathetic nervous system and some central nervous system and sensory neurons. Nerve growth factor is necessary for axon growth and also for initiating new neuronal connections with other cells. The role of NGFs in preventing the degeneration of brain cells is being explored in research into Alzheimer’s disease.... nerve growth factor

Nerve Impulse

the electrical activity in the membrane of a *neuron that – by its rapid spread from one region to the next – is the means by which information is transmitted within the nervous system along the axons of the neurons. The membrane of a resting nerve is charged (polarized) because of the different concentrations of ions inside and outside the cell. When a nerve impulse is triggered, a wave of *depolarization spreads, and ions flow across the membrane (see action potential). Until the nerve has undergone *repolarization no further nerve impulses can pass.... nerve impulse

Nerve Regeneration

the growth of new nerve tissue, which occurs at a very slow rate (1–2 mm per day) after a nerve has been severed and is often partially or totally incomplete. *Microsurgery has improved the results by facilitating primary repair in the immediate aftermath of injury. See also axonotmesis; neurotmesis.... nerve regeneration

Nesbit’s Operation

an operation devised to surgically straighten a congenitally curved penis but now more frequently employed to correct the penile curvature caused by *Peyronie’s disease. The procedure can often result in penile shortening. [R. M. Nesbit (20th century), US surgeon]... nesbit’s operation

Nesidioblastosis

n. a rare condition of childhood in which abnormal cells in the pancreas fail to mature properly and secrete a selection of hormones (including insulin) in an uncontrolled manner. This causes a variety of problems, including recurrent *hypoglycaemia. It can sometimes be treated with medication; if this fails, surgical removal of a portion of the pancreas may be necessary.... nesidioblastosis

Nets

neuroendocrine tumours. See neuroendocrine system.... nets

Neur

(neuro-) combining form denoting nerves or the nervous system.... neur

Neural Arch

see vertebra.... neural arch

Neural Crest

the two bands of ectodermal tissue that flank the *neural plate of the early embryo. Cells of the neural crest migrate throughout the embryo and develop into sensory nerve cells and peripheral nerve cells of the autonomic nervous system.... neural crest

Neural Plate

the strip of ectoderm lying along the central axis of the early embryo that forms the *neural tube and subsequently the central nervous system.... neural plate

Neural Spine

the spinous process situated on the neural arch of a *vertebra.... neural spine

Neuraminidase

(NA, N) a glycoprotein projecting from the surface layer of the lipid bilayer envelope of *influenza virions. It attacks sialic acid residues on host cells and may be involved in virus release. It is a key target for antibody attack and therefore is important in vaccination.... neuraminidase

Neurectasis

n. the surgical procedure for stretching a peripheral nerve.... neurectasis

Neurilemmoma

(neurinoma) n. a benign slow-growing tumour that arises from the neurilemma of a nerve fibre.... neurilemmoma

Neurinoma

n. see neurilemmoma.... neurinoma

Neuroanatomy

n. the study of the structure of the nervous system, from the gross anatomy of the brain down to the microscopic details of neurons.... neuroanatomy

Neurobiotaxis

n. the predisposition of a nerve cell to move towards the source of its stimuli during development.... neurobiotaxis

Neuroblast

n. any of the nerve cells of the embryo that give rise to functional nerve cells (neurons).... neuroblast

Neurocardiogenic Syncope

(malignant vasovagal syndrome) recurrent loss of consciousness due to a drop in blood pressure mediated by *vasodilatation, *bradycardia, or a combination of the two. Attacks resemble a simple faint, but can be very disabling because they are much more frequent and severe. Treatment comprises increased fluid and salt intake together with training in postural manoeuvres that may prevent attacks. A variety of drug treatments is available, but these are commonly ineffective. Implantation of a permanent *pacemaker may be required if profound bradycardia is a feature.... neurocardiogenic syncope

Neurocranium

n. the part of the skull that encloses the brain.... neurocranium

Neuroendocrine System

the system of dual control of certain activities of the body by means of both nerves and circulating hormones. The functioning of the autonomic nervous system is particularly closely linked to that of the pituitary and adrenal glands. The system can give rise to neuroendocrine tumours (NETs), which have special structural features and often produce active hormones. See also neurohormone; neurosecretion.... neuroendocrine system

Neuroepithelioma

n. a malignant tumour of the retina of the eye. It is a form of *glioma and may spread into the brain if not treated early.... neuroepithelioma

Neuroepithelium

n. a type of epithelium associated with organs of special sense. It contains sensory nerve endings and is found in the retina, the membranous labyrinth of the inner ear, the mucous membrane lining the nasal cavity, and the taste buds. —neuroepithelial adj.... neuroepithelium

Neurofibril

n. one of the microscopic threads of cytoplasm found in the cell body of a *neuron and also in the *axoplasm of peripheral nerves.... neurofibril

Neurofibrillary Tangles

twisted filaments composed of an abnormal form of tau protein, which normally occurs in microtubules (structural elements) of cells. They are found in the brains of patients with *Alzheimer’s disease.... neurofibrillary tangles

Neurofibroma

n. a benign tumour growing from the fibrous coverings of a peripheral nerve: it arises from *Schwann cells, lacks a capsule (therefore it may incorporate nerve fibres), and is usually symptomless. When it develops from the sheath of a nerve root, it causes pain and may compress the spinal cord. A schwannoma is similar but encapsulated (sometimes the terms are used synonymously).... neurofibroma

Neurogenesis

n. the growth and development of nerve cells.... neurogenesis

Neurohormone

n. a hormone that is produced within specialized nerve cells and is secreted from the nerve endings into the circulation. Examples are the hormones oxytocin and vasopressin, produced within the nerve cells of the hypothalamus and released into the circulation in the posterior pituitary gland, and noradrenaline, released from *chromaffin tissue in the adrenal medulla.... neurohormone

Neurohumour

n. a *neurohormone or a *neurotransmitter.... neurohumour

Neurohypophysis

n. the posterior lobe of the *pituitary gland.... neurohypophysis

Neurolemma

n. see neurilemma.... neurolemma

Neuroleptic Malignant Syndrome

a life-threatening syndrome seen after starting *antipsychotic medication. It is characterized by confusion, muscle rigidity, fever, pallor and sweating, urinary incontinence, and a high level of *creatine kinase. Its symptoms can appear similar to *catatonia. Treatment in a high-dependency unit with high-dose benzodiazepines and immediate cessation of antipsychotic drugs is usually indicated.... neuroleptic malignant syndrome

Neuromyelitis Optica

(Devic’s disease) a condition that resembles multiple sclerosis. The diagnosis is confirmed by the finding of the antiaquaparin-4 antibody (NMO IgG antibody). Typically there is a transverse *myelitis, producing paralysis and numbness of the legs and trunk below the inflamed spinal cord, and *retrobulbar (optic) neuritis affecting both optic nerves. The attacks of myelitis and optic neuritis may coincide or they may be separated by days or weeks. Recovery from the initial attack is often incomplete and severe relapses occur commonly unless treatment with immunosuppressive therapies is started.... neuromyelitis optica

Neuronophagia

n. the process whereby damaged or degenerating nerve cells finally disintegrate and are removed by scavenger cells (*phagocytes).... neuronophagia

Neuronoplasty

n. reconstructive surgery for damaged or severed peripheral nerves.... neuronoplasty

Neuropathic Arthritis

(Charcot’s joint) a condition leading to progressive destruction and deformity of weight-bearing joints, resulting from damage to the sensory nerves that supply them. Causes include diabetes mellitus (see diabetic neuropathy), *tabes dorsalis, *syringomyelia, leprosy, congenital insensitivity to pain, and other neurological problems. Patients develop an unstable painless swollen joint; treatment is focused on limitation of activity and bracing.... neuropathic arthritis

Neuropeptide Y

a peptide, related to *pancreatic polypeptide, that is found in the central and peripheral nervous systems (it is particularly abundant in the hypothalamus). It has a variety of actions, including stimulation of appetite, gastrointestinal regulation, reproduction, memory, circadian rhythms, and cardiovascular functioning.... neuropeptide y

Neurophysiology

n. the study of the complex chemical and physical changes that are associated with the activity of the nervous system.... neurophysiology

Neuropil

n. nerve tissue that is visible microscopically as a mass of interwoven and interconnected nerve endings, dendrites, and other neuron components, rather than an ordered array of axons.... neuropil

Neuroplasticity

(neural plasticity) n. the ability of the brain to develop new neurons and/or new synapses in response to stimulation and learning. Recent research shows that the brain retains its plasticity throughout life, more or less, depending on the person’s state of health, etc. Following injury to the brain, neuroplasticity may allow uninjured areas to take over the processes previously carried out by the injured areas.... neuroplasticity

Neuroretinitis

n. combined inflammation of the optic nerve and the retina.... neuroretinitis

Neurosecretion

n. any substance produced within, and secreted by, a nerve cell. Important examples are the hormone-releasing factors produced by the cells of the *hypothalamus and released into blood vessels of the pituitary gland, on which they act.... neurosecretion

Neuroticism

n. a dimension of personality derived from questionnaires and psychological tests. People with high scores in neuroticism are anxious and intense, emotionally unstable, and more prone to develop *neurosis.... neuroticism

Neurotmesis

n. the complete severance of a peripheral nerve, which is associated with degeneration of the nerve fibres distal to the point of severance and slow *nerve regeneration. Compare axonotmesis; neurapraxia.... neurotmesis

Neurotomy

n. the surgical procedure of severing a nerve.... neurotomy

Neurotoxic

adj. poisonous or harmful to nerve tissue and dental pulp cells. —neurotoxicity n.... neurotoxic

Neurotrophic

adj. relating to the growth and nutrition of neural tissue in the body.... neurotrophic

Neurotropic

adj. growing towards or having an affinity for neural tissue. The term may be applied to viruses, chemicals, or toxins.... neurotropic

Newton

n. the *SI unit of force, equal to the force required to impart to 1 kilogram an acceleration of 1 metre per second per second. Symbol: N.... newton

Nexus

n. (in anatomy) a connection or link.... nexus

Number Needed To Treat

(NNT) the average number of patients who need to be treated to prevent one additional negative outcome. This is the reciprocal of the absolute risk reduction: the difference between the risk of an adverse event in control and intervention groups.... number needed to treat

Ophthalmic Nerve

the smallest of the three branches of the *trigeminal nerve. It supplies sensory fibres to the eyeball, conjunctiva, and lacrimal gland, to a small region of the nasal mucous membrane, and to the skin of the nose, brows, and scalp.... ophthalmic nerve

Penile Intraepithelial Neoplasia

(PIN) cellular changes affecting the glans, prepuce, or penile shaft that precede the invasive stages of cancer of the penis. There are three stages (PIN I, II, or III) based on the degree of *dysplasia. The pathological features of PIN III indicate *carcinoma in situ, known as *erythroplasia of Queyrat and Bowen’s disease.... penile intraepithelial neoplasia

Percutaneous Nephrolithotomy

(PCNL) a technique of removing stones from the kidney via a *nephroscope passed into the kidney through a dilated track established from the skin surface into the renal pelvis.... percutaneous nephrolithotomy

Peripheral Neuropathy

(polyneuropathy, peripheral neuritis) any of a group of disorders affecting the sensory and/or motor nerves in the peripheral nervous system. They tend to start distally, in the fingers and toes, and progress proximally. Symptoms include pins and needles, stabbing pains and a numbness on the sensory side, and weakness of the muscles. The most common causes of peripheral neuropathy are diabetes, alcohol, certain drugs, and such infections as HIV; genetic causes of peripheral neuropathy include amyloidosis and *Charcot-Marie-Tooth disease. The diagnosis may be established by neurophysiological tests, blood tests, and occasionally a nerve biopsy.... peripheral neuropathy

Pilomotor Nerves

sympathetic nerves that supply muscle fibres in the skin, around the roots of hairs. Activity of the sympathetic nervous system causes the muscles to contract, raising the hairs and giving the *gooseflesh effect of fear or cold.... pilomotor nerves

Prostatic Intraepithelial Neoplasia

(PIN) abnormal cells in the prostate that are not cancer, but may be associated with cancer within the prostate. Typically, PIN will be found in prostate biopsies taken because levels of *prostate specific antigen are elevated. Multifocal high-grade PIN (HGPIN) on a prostate biopsy may indicate that another set of prostate biopsies should be taken in the future.... prostatic intraepithelial neoplasia

Saphenous Nerve

a large branch of the *femoral nerve that arises in the upper thigh, travels down on the inside of the leg, and supplies the skin from the knee to below the ankle with sensory nerves.... saphenous nerve

Sensory Nerve

a nerve that carries information inwards, from an outlying part of the body towards the central nervous system. Different sensory nerves convey information about temperature, pain, touch, taste, etc., to the brain. Compare motor nerve.... sensory nerve

Sero-negative Arthritis

an arthritis in which rheumatoid factor or anticitrullinated protein antibodies (ACPA) are not present in the serum. See also spondyloarthropathy.... sero-negative arthritis

Shunt Nephritis

nephritis associated with infected indwelling shunts. The infection is usually with staphylococci (S. epidermidis) and patients present with anorexia, malaise, arthralgia, and low-grade fever. Purpura, anaemia, and hepatosplenomegaly may be found and urine analysis shows heavy proteinuria, often with a *nephrotic syndrome and haematuria. Treatment usually involves removal of the infected shunt as well as antibiotics.... shunt nephritis

Sickle-cell Nephropathy

progressive renal disease developing in 5–8% of patients with *sickle-cell disease. Infarcts in the cortex can occur with sickle-cell crises and present with pain and haematuria. Acute or more insidious damage to the medulla will lead to a urinary concentrating defect and later to papillary necrosis and/or fibrosis. Occlusion of vessels within the glomerular capillary tuft leads to a secondary form of *focal segmental glomerulosclerosis and can present with the *nephrotic syndrome.... sickle-cell nephropathy

Singular Nerve

a small subdivision of the *vestibular nerve that carries information from the posterior *semicircular canal to the brain. Singular neurectomy is a surgical procedure to divide the singular nerve, occasionally used in the treatment of *benign paroxysmal positional vertigo.... singular nerve

Spinal Accessory Nerve

see accessory nerve.... spinal accessory nerve

Splanchnic Nerves

the series of nerves in the sympathetic system that are distributed to the blood vessels and viscera, passing forwards and downwards from the chain of sympathetic ganglia near the spinal cord to enter the abdomen and branch profusely.... splanchnic nerves

Stop Needle

a surgical needle with a shank that has a protruding collar to stop it when the needle has been pushed a prescribed distance into the tissue. A stop needle has the eye at the tip.... stop needle

Surgical Neck

the constriction of the shaft of the *humerus, below the head. It is frequently the point at which fracture of the humerus occurs.... surgical neck

Toxic Epidermal Necrolysis

(TEN, Lyell’s syndrome) a severe reaction to medications with a high mortality rate. Medications causing TEN include sulfonamides, anticonvulsants, antiretrovirals, and allopurinol. Widespread separation of the dead epidermal layer from underlying skin occurs, with consequent problems due to skin failure: impaired temperature regulation, infection risk, severe pain, etc. Mucous membranes are commonly affected, including the eyes (sometimes leading to blindness), mouth, and genitalia. Multi-organ failure may occur. Treatments include stopping the offending medication, good supportive nursing (usually in an ITU or HDU setting), antibiotics where appropriate, and intravenous immunoglobulin or ciclosporin.... toxic epidermal necrolysis

Tumour Necrosis Factor

(TNF) either of two proteins, TNF-? or TNF-?, that function as *cytokines. Produced by macrophages, monocytes, T lymphocytes, and various other cells, they mediate many responses, including inflammation, and have a marked action against tumour cells. Anti-TNF drugs (see cytokine inhibitor) are used in the treatment of several disorders, especially rheumatoid arthritis and ankylosing spondylitis.... tumour necrosis factor

Turkel’s Needle

a specially designed needle for purposes of transrectal prostatic biopsy.... turkel’s needle

Vasomotor Nerve

any nerve, usually belonging to the autonomic nervous system, that controls the circulation of blood through blood vessels by its action on the muscle fibres within their walls or its action on the heartbeat. The *vagus nerve slows the heart and reduces its output, but sympathetic nerves increase the rate and output of the heart and increase blood pressure by causing the constriction of small blood vessels at the same time.... vasomotor nerve

Veress Needle

a surgical needle used prior to *laparoscopy to gain access to the peritoneal cavity and allow insufflation of carbon dioxide (*pneumoperitoneum) before the insertion of a sharp *trocar. It has an outer cutting sheath and an inner spring-loaded gas-transmitting safety sheath and is inserted into the abdomen either in the midsagittal plane at the lower margin or base of the umbilicus or at *Palmer’s point. [J. Veress (20th century), Hungarian surgeon]... veress needle

Vestibular Nerve

the division of the *vestibulocochlear nerve that carries impulses from the semicircular canals, utricle, and saccule of the inner ear to the brain, conveying information about the body’s posture and movements in space and allowing coordination and balance.... vestibular nerve

Vestibular Neuronitis

(vestibular neuritis) a condition characterized by the sudden onset of vertigo without hearing loss or other auditory symptoms (compare labyrinthitis). It generally lasts days to weeks and the cause is unknown.... vestibular neuronitis

Vulval Intraepithelial Neoplasia

(VIN) premalignant disease of the vulva, which has histological features and terminology similar to those of *cervical intraepithelial neoplasia (CIN). Viral aetiological factors, such as HPV, are thought to be involved. The most common presenting symptom is itch, but VIN may be asymptomatic and detected only during treatment of preinvasive or invasive lesions of the cervix or lower genital tract.... vulval intraepithelial neoplasia

Ziehl–neelsen Stain

an acid-fast *carbol fuchsin stain used specifically for identifying the tubercle bacillus. [F. Ziehl (1857–1926), German bacteriologist; F. K. A. Neelsen (1854–94), German pathologist]... ziehl–neelsen stain

Fir Needle, Silver

Abies alba

FAMILY: Pinaceae

SYNONYMS: A. pectinata, whitespruce, European silver fir, edeltanne, weisstanne, templin (cone oil), Strassburg or Vosges turpentine (oil), fir needle (oil).

GENERAL DESCRIPTION: A relatively small coniferous tree, with a regular pyramidal shape and a silvery white bark, grown chiefly for timber and as Christmas trees.

DISTRIBUTION: Native to north European mountainous regions; cultivated mainly in Switzerland, Poland, Germany, France, Austria and especially Yugoslavia.

OTHER SPECIES: Oils that are distilled from the twigs and needles of various members of the coniferous families, Abies, Larix, Picea, Pinus, and Tsuga, are all commonly called fir needle oil – it is therefore important to know the specific botanical name. There are many other members of the fir or Abies family, notably the Canadian balsam (A. balsamifera) and the Siberian fir (A. siberica), the most popular fir needle oil in Europe and the USA due to its fine fragrance. Others include the Japanese fir needle oil from A.mayriana or A.sachalinensis. See also entries on spruce, pines and the Botanical Classification section.

HERBAL/FOLK TRADITION: It is highly esteemed on the Continent for its medicinal virtues and its fragrant scent. It is used mainly for respiratory complaints, fever, muscular and rheumatic pain.

ACTIONS: Analgesic, antiseptic (pulmonary), antitussive, deodorant, expectorant, rubefacient, stimulant, tonic.

EXTRACTION: Essential oil by steam distillation from the 1. needles and young twigs, and 2. fir cones, broken up pieces (templin oil)

CHARACTERISTICS: 1. A colourless or pale yellow liquid of pleasing, rich, sweet-balsamic odour. 2. Similar to the needle oil, but with a more orange-like fragrance. It blends well with galbanum, labdanum, lavender, rosemary, lemon, pine and marjoram.

PRINCIPAL CONSTITUENTS: 1. Santene, pinene, limonene, bornyl acetate, lauraldehyde among others. 2. Pinene, limonene, borneol, bornyl acetate, among others.

SAFETY DATA: Non-toxic, non-irritant (except in high concentration), non-sensitizing.

AROMATHERAPY/HOME: USE

Circulation Muscles And Joints: Arthritis, muscular aches and pains, rheumatism.

Respiratory System: Bronchitis, coughs, sinusitis, etc.

Immune System: Colds, fever, ’flu.

OTHER USES: Employed as an ingredient in some cough and cold remedies and rheumatic treatments. Used as a fragrance component in deodorants, room sprays, disinfectants, bath preparations, soaps and perfumes.... fir needle, silver

Nervine

strengthening and toning to the nerves and nervous system.... nervine

Neroli

Citrus aurantium var. amara

FAMILY: Rutaceae

SYNONYMS: C. vulgaris, C. bigaradia, orange blossom, orange flower, neroli bigarade.

GENERAL DESCRIPTION: An evergreen tree up to 10 metres high with glossy dark green leaves and fragrant white flowers. There are two flowering seasons when the blossom is picked, one in May and another in October (in mild weather). See also bitter orange.

DISTRIBUTION: Native to the Far East, but well adapted to the Mediterranean climate. Major producers include Italy, Tunisia, Morocco, Egypt, America and especially France.

OTHER SPECIES: The sweet orange (C. aurantium var. dulcis) is also used to make an absolute oil called neroli Portugal or neroli petalae – however, it is less fragrant and considered of inferior quality.

HERBAL/FOLK TRADITION: This oil was named after a princess of Nerola in Italy, who loved to wear it as a perfume. Orange flowers have many folk associations. They were used in bridal bouquets and wreaths, to calm any nervous apprehension before the couple retired to the marriage bed.

On the Continent an infusion of dried flowers is used as a mild stimulant of the nervous system, and as a blood cleanser. The distillation water, known as orange flower water, is a popular cosmetic and household article.

ACTIONS: Antidepressant, antiseptic, antispasmodic, aphrodisiac, bactericidal, carminative, cicatrisant, cordial, deodorant, digestive, fungicidal, hypnotic (mild), stimulant (nervous), tonic (cardiac, circulatory).

EXTRACTION: 1. A concrete and absolute are produced by solvent extraction from the freshly picked flowers. 2. An essential oil is, produced by steam distillation from the freshly picked flowers. An orange flower water and an absolute are produced as a byproduct of the distillation process.

CHARACTERISTICS: 1. The absolute is a dark brown or orange viscous liquid with a fresh, delicate yet rich, warm sweet-floral fragrance; very true to nature. It blends well with jasmine, benzoin, myrrh and all citrus oils. 2. The oil is a pale yellow mobile liquid (darkening with age) with a light, sweet-floral fragrance and terpeney topnote. Blends well with virtually all oils: chamomile, coriander, geranium, benzoin, clary sage, jasmine, lavender, rose, ylang ylang, lemon and other citrus oils.

PRINCIPAL CONSTITUENTS: Linalol (34 per cent approx.), linalyl acetate (6–17 per cent), limonene (15 per cent approx.), pinene, nerolidol, geraniol, nerol, methyl anthranilate, indole, citral, jasmone, among others.

SAFETY DATA: Non-toxic, non-irritant, nonsensitizing, non-phototoxic.

AROMATHERAPY/HOME: USE

Skin care: Scars, stretch marks, thread veins, mature and sensitive skin, tones the complexion, wrinkles.

Circulation muscles and joints: Palpitations, poor circulation.

Digestive system: Diarrhoea (chronic), colic, flatulence, spasm, nervous dyspepsia.

Nervous system: Anxiety, depression, nervous tension, PMT, shock, stress-related conditions – ‘I find that by far the most important uses of neroli are in helping with problems of emotional origin.’.

OTHER USES: Neroli oil and orange flower water are used to flavour pharmaceuticals. The absolute is used extensively in high-class perfumery work, especially oriental, floral and citrus blends; also as a fixative. The oil is used in eau-de-cologne and toilet waters (traditionally with lavender, lemon, rosemary and bergamot). Limited use as a flavour ingredient in foods, alcoholic and soft drinks.... neroli




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