Neointimal hyperplasia Health Dictionary

Neointimal Hyperplasia: From 1 Different Sources


a pathological process involved in *atherosclerosis of arteries and vein grafts, and in *restenosis, that may be in response to angioplasty and stent placement. Damage to the endothelium of the artery exposes the underlying smooth muscle cells in the *media to cytokines, growth factors, and other plasma components in the circulation, which results in loss of their contractile characteristics. These abnormal muscle cells migrate to the *intima, where they proliferate and eventually form a thick layer of tissue (neointima), which occludes the artery.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Congenital Adrenal Hyperplasia

See ADRENOGENITAL SYNDROME and GENETIC DISORDERS.... congenital adrenal hyperplasia

Hyperplasia

Hyperplasia means an abnormal increase in the number of cells in a tissue.... hyperplasia

Benign Prostatic Hyperplasia

(BPH) A medical term for enlargement of the prostate gland (see prostate, enlarged).... benign prostatic hyperplasia

Benign Prostatic Hypertrophy, Or Hyperplasia

(BPH) The benign buildup in the prostate of “warts” or epithelial neoplasias that can block or interrupt urination, and which are usually concurrent with moderate prostate enlargement. They cause a dull ache on urination, ejaculation, and/or defecation. The diagnosis is medical, since the same subjective conditions can result from cancer of the prostate. BPH is common in men over fifty and can be the result either of diminished production of complete testosterone or poor pelvic circulation. Alcohol, coffee, speed, and antihistamines can all aggravate the problem.... benign prostatic hypertrophy, or hyperplasia

Adrenal Hyperplasia, Congenital

An uncommon genetic disorder in which an enzyme defect blocks the production of corticosteroid hormones from the adrenal glands. Excessive amounts of androgens (male sex hormones) are produced, which can result in abnormal genital development in an affected fetus. Other effects include dehydration, weight loss, low blood pressure, and hypoglycaemia. Hyperplasia (enlargement) of the adrenal glands occurs and there is excessive skin pigmentation in skin creases and around the nipples.

In severe cases, the disorder is apparent soon after birth. In milder cases, symptoms appear later, sometimes producing premature puberty in boys and delayed menstruation, hirsutism, and potential infertility in girls.

Congenital adrenal hyperplasia is confirmed by measuring corticosteroid hormones in blood and urine. Treatment is by hormone replacement. If this is started early, normal sexual development and fertility usually follow.... adrenal hyperplasia, congenital

Gingival Hyperplasia

See hyperplasia, gingival.... gingival hyperplasia

Hyperplasia, Gingival

Abnormal enlargement of the gums.

Causes include gingivitis, persistent breathing through the mouth, the anticonvulsant drug phenytoin, and ill-fitting dentures.

Surgical treatment may be needed.... hyperplasia, gingival

Endometrial Hyperplasia

an increase in the thickness of the cells of the *endometrium, usually due to prolonged exposure to unopposed oestrogen, which can be endogenous, as in anovular menstrual cycles; or exogenous, deriving, for example, from *hormone replacement therapy or an oestrogen-secreting tumour. It is classified as simple, complex, or atypical. Endometrial hyperplasia most commonly presents with abnormal uterine bleeding and accounts for 15% cases of postmenopausal bleeding. It may also be asymptomatic, and in some cases regresses spontaneously without ever being detected. The presence of atypical cells may lead to *endometrial cancer. Treatment can include progestogen therapy or surgery (see endometrial ablation); hysterectomy is advised when atypical changes are present.... endometrial hyperplasia



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