Megha Health Dictionary

Jacq.

Synonym: Ambroma augusta Linn. f.

Family: Sterculiaceae.

Habitat: Throughout the hotter and moister parts of India, from Punjab and Uttar Pradesh, eastwards to Arunachal Pradesh, Assam, Meghalaya and Tripura, ascending to 1,200 m, southwards in Peninsular India.

English: Perennial Indian Hemp, Devil's Cotton.

Ayurvedic: Pishaacha Kaarpaasa, Pivari.

Unani: Ulat-kambal.

Siddha/Tamil: Sivapputtuti.

Folk: Kumal, Sanukapaasi.

Action: Rootbark—emmena- gogue (used for dysmenorrhoea, amenorrhoea), abortifacient, galac- totrophic.

The root contains abromine (betaine), friedelin, abromasterol, abro- masterol A, choline, beta-sitosterol, stigmasterol and octacosanol. Leaves, reported to be useful in treating uterine disorders, contain taraxerol, its acetate and lupeol.

Dosage: Leaf juice—10-20 ml. Rootbarkpowder—3-6 g. (CCRAS.)... abroma augusta

Linn.

Family: Acanthaceae.

Habitat: Common in tidal forests along the East and West coasts; also distributed in Meghalaya and the Andamans.

English: Sea Holly.

Ayurvedic: Krishna Saraiyaka. (Blue-flowered Katasaraiyaa.)

Siddha/Tamil: Kollimulli.

Folk: Hargozaa.

Action: Decoction—antacid (used in dyspepsia with acid eructations), also diuretic (used in dropsy and bilious swellings). Aerial parts show effect on nictitating membrane. The root is a cordial attenuant and is used in debility associated with asthma, paralysis, leucorrhoea.

The air-dried plant contains an alkaloid, acanthicifoline, and a flavone.... acanthus ilicifolius

auct non L.

Synonym: A. pilosa Hook.f. non Ledeb.

A. pilosa Ledeb. var. nepalensis (D. Don) Nakai

Family: Rosacae.

Habitat: The Himalayas from Kashmir to West Bengal at 9003,000 m, and in Arunachal Pradesh, Nagaland and Meghalaya.

English: Agrimony, Stickle Wort.

Unani: Ghaafis.

Folk: Belu.

Action: Astringent, anti- inflammatory, hepatic, cholagogue, diuretic, mild haemostatic, antibacterial. Used for irritations and infections of the intestinal tract, gallbladder diseases, hyperacidity, colic, urinary disorders (bed- wetting, incontinence), sluggish liver, mucus membrane inflammations; externally for ulcerated and discharging skin, psoriasis and seborrhoic eczemas.

Key application: In mild, nonspecific, acute diarrhoea and in inflammation of oral and pharyngeal mucosa; as astringent. (German Commission E, The British Herbal Pharmacopoeia.)

The herb contains condensed tannins up to 8%, coumarins, flavonoids (glucosides of luteolin, apigenin and quercetin), polysaccharides, volatile oil. Luteolin 7-glucoside shows a chole- gogic action. Aqueous extracts inhibited Mycobacterium tuberculosis, also strains resistant to streptomycin and p-aminosalicylate. Essential oil is antibacterial, active against Bacillus sub- tilis.

The ethanolic extracts of the herb are used for their antiviral properties. (Natural Medicines Comprehensive Database, 2007.)

Coumarins interact with anticoagulants, and drugs that increase the risk of bleeding Furanocoumarin content increase photosensitivity. (Sharon M. Herr.)... agrimonia eupatoria

DC.

Family: Compositae; Asteraceae.

Habitat: The Himalayas from Kashmir to Bhutan at altitudes of 2,400 m, extending to Khasi hills of Meghalaya.

Folk: Karui Buuti (Garhwal).

Action: Powdered roots—used for quick relief from acute stomach ache; diuretic.

A related sp., A. latifolia Sch-Bip., is used as an adulterant to Podophyllum emodi.... ainsliaea aptera

Rosc.

Family: Zingiberaceae.

Habitat: Eastern Himalayas, Assam, Khasi Hills, Meghalaya, up to 1,500 m, and western Ghats of Kerala.

Folk: Saliyeridumpa (Tamil).

Action: Rhizome—employed to cure sores. Fruits—emetic (used with salt).

The rhizomes yield essential oil consisting of methyl cinnamate as chief constituent.... alpinia malaccensis

Hochr.

Synonym: A. roxburghiana A. Juss.

Family: Malpighiaceae.

Habitat: Eastern Himalayas, Assam, Meghalaya, Orissa and peninsular India.

Folk: Chuttakulaa-tigaa (Telugu).

Action: The extract of aerial parts— hypotensive.... aspidopterys indica

Vahl.

Synonym: J. azoricum Linn.

Family: Oleaceae.

Habitat: Assam, Mizoram, Meghalaya and Western Ghats.

Ayurvedic: Maalati (var.).

Siddha/Tamil: Ramabanam mullai.

Folk: Chameli (var.).

Action: See Jasminum officinale.... jasminum flexile

Linn.

Family: Liliaceae, Alliaceae.

Habitat: Native to temperate northern Europe and the U.S.; distributed in the western Himalayas from Kashmir to Kumaon at altitudes of 2,400-3,000 m.

English: Chives.

Action: Used in place of young onions.

An alcoholic extract of the bulbs exhibited hypotensive and cardiac depressant activity.

The aerial parts (chives) gave alliins (alkylcysteine sulfoxides), particularly methyl alliin and pentylalliin.

Allium tuberosum Rottl. ex Spreng, found in eastern India and western Himalayas, is equated with Chinese Chives. It is available in Meghalaya.... allium schoenoprasum

Linn.

Family: Amaranthaceae.

Habitat: Cultivated fields, waste places and along roadsides.

English: Spiny Amaranth, Thorny Amaranth, Spiny Pigweed.

Ayurvedic: Tanduliya, Tandulaka, Meghnaad, Megharava, Vishaghn, Alpamaarish.

Siddha/Tamil: Mullukkeerai.

Folk: Katili-chaulai.

Action: Galactogenic, laxative, emollient, spasmolytic, diuretic. Pollen extract—used for allergic asthma and allergic rhinitis. Root— used in menorrhoea.

Plant contains sterols. Leaves and stems contain alpha-spinasterol and hentriacontane. Leaves also contain amino acids with high content of lysine.

Dosage: Whole plant—10-20 ml juice; 400-800 mg powder. (CCRAS.)... amaranthus spinosus

Wall. ex Nees

Family: Acanthaceae.

Habitat: Throughout India, from Himachal Pradesh to Assam and Mizoram, and all over southern India.

English: Creat.

Ayurvedic: Kaalmegha, Bhuunimba, Bhuuminimbaka, Vishwambharaa, Yavtikta, Kalpanaatha, Kiraata-tikta (var.).

Unani: Kiryaat.

Siddha/Tamil: Nilavembu.

Action: Hepatoprotective, cholin- ergic, antispasmodic, stomachic, anthelmintic, alterative, blood purifier, febrifuge. It acts well on the liver, promoting secretion of bile. Used in jaundice and torpid liver, flatulence and diarrhoea of children, colic, strangulation of intestines and splenomegaly; also for cold and upper respiratory tract infections.

Key application: As bitter tonic, febrifuge and hepatoprotective. (Indian Herbal Pharmacopoeia.)

Kaalmegha, officinal in IP, consists of dried leaves and tender shoots, which yield not less than 1% andro- grapholide on dry-weight basis.

Several active constituents have been identified from the leaf and rhizome, including andrographolide, deoxyan- drographolide and other diterpenes.

Andrographolide exhibited strong choleretic action when administered i.p. to rats. It induces increase in bile flow together with change in physical properties of bile secretion. It was found to be more potent than sily- marin.

Andrographolide was found to be almost devoid of antihepatitis-B virus surface antigen-like activity (when compared with picroliv.)

The leaf and stem extracts of Kaal- megha/andrographolide given s.c. or orally did not change blood sugar level of normal or diabetic rats.

Alcoholic extract of the plant exhibited antidiarrhoeal activity against E. coli enterotoxins in animal models.

Clinical evidence of effectiveness of andrographis in humans is limited to the common cold. Preliminary evidence suggests that it might increase antibody activity and phagocytosis by macrophages, and might have mast cell-stabilizing and antiallergy activity. (Natural Medicines Comprehensive Database, 2007.)

The herb is contraindicated inbleed- ing disorders, hypotension, as well as male and female sterility (exhibited infertility in laboratory animals).

Dosage: Whole plant—5-10 ml juice; 50-100 ml decotion; 1-3 g powder. (CCRAS.)... andrographis panicultata

Dioscorea spp.

Dioscoreaceae

The growing need for steroidal drugs and the high cost of obtaining them from animal sources led to a widespread search for plant sources of steroidal sapogenins, which ultimately led to the most promising one. It is the largest genus of the family constituted by 600 species of predominantly twining herbs. Among the twining species, some species twine clockwise while others anti-clockwise (Miege, 1958). All the species are dioceous and rhizomatous. According to Coursey (1967), this genus is named in honour of the Greek physician Pedenios Dioscorides, the author of the classical Materia Medica Libri Quinque. Some of the species like D. alata and D. esculenta have been under cultivation for a long time for their edible tubers. There are about 15 species of this genus containing diosgenin. Some of them are the following (Chopra et al, 1980).

D. floribunda Mart. & Gal.

D. composita Hemsl; syn. D. macrostachya Benth.

D. deltoidea Wall. ex Griseb; syn. D. nepalensis Sweet ex Bernardi.

D. aculeata Linn. syn. D. esculenta

D. alata Linn. syn. D. atropurpurea Roxb.

D. Globosa Roxb; D. purpurea Roxb; D. rubella Roxb.

D. bulbifera Linn. syn. D. crispata Roxb.

D. pulchella Roxb.; D. sativa Thunb. Non Linn.

D. versicolor Buch. Ham. Ex Wall.

D. daemona Roxb. syn. D. hispida Dennst.

D. oppositifolia Linn.

D. pentaphylla Linn. syn. D. jacquemontii Hook. f.

D. triphylla Linn.

D. prazeri Prain & Burkil syn. D. clarkei Prain & Burkill

D. deltoidea Wall. var. sikkimensis Prain

D. sikkimensis Prain & Burkill

Among the above said species, D. floribunda, D. composita and D. deltoidea are widely grown for diosgenin production.

1. D. floribunda Mart. & Gal D. floribunda Mart. & Gal. is an introduction from central America and had wide adaptation as it is successfully grown in Karnataka, Assam, Meghalaya, Andaman and Goa. The vines are glabrous and left twining. The alternate leaves are borne on slender stems and have broadly ovate or triangular ovate, shallowly cordate, coriaceous lamina with 9 nerves. The petioles are 5-7cm long, thick and firm. Variegation in leaves occurs in varying degrees. The male flowers are solitary and rarely in pairs. Female flowers have divericate stigma which is bifid at apex. The capsule is obovate and seed is winged all round. The tubers are thick with yellow coloured flesh, branched and growing upto a depth of 30cm (Chadha et al, 1995).

2. D. composita Hemsl.

D. composita Hemsl. according to Knuth (1965) has the valid botanical name as D. macrostachya Benth. However, D. composita is widely used in published literature. It is a Central American introduction into Goa, Jammu, Bangalore, Anaimalai Hills of Tami Nadu and Darjeeling in W. Bengal. The vines are right twinning and nearly glabrous. The alternate leaves have long petioles, membraneous or coriaceous lamina measuring upto 20x18cm, abruptly acute or cuspidate-acuminate, shallowly or deeply cordate, 7-9 nerved. The fasciculate-glomerate inflorescence is single or branched with 2 or 3 sessile male flowers having fertile stamens. Male fascicle is 15-30cm long. The female flowers have bifid stigma. Tubers are large, white and deep-rooted (upto 45cm) (Chadha et al, 1995).

3. D. deltoidea Wall. ex. Griseb.

D. deltoidea Wall. ex. Griseb. is distributed throughout the Himalayas at altitudes of 1000-3000m extending over the states of Jammu-Kashmir, H. P, U. P, Sikkim and further into parts of W. Bengal. The glabrous and left twining stem bears alternate petiolate leaves. The petioles are 5-12 cm long. The lamina is 5-15cm long and 4-12cm wide widely cordate. The flowers are borne on axillary spikes, male spikes 8-40cm long and stamens 6. Female spikes are 15cm long, 3. 5cm broad and 4-6 seeded. Seeds are winged all round. Rhizomes are lodged in soil, superficial, horizontal, tuberous, digitate and chestnut brown in colour (Chadha et al, 1995). D. deltoidea tuber grows parallel to ground covered by small scale leaves and is described as rhizome. The tubers are morphologically cauline in structure with a ring of vascular bundles in young tubers which appear scattered in mature tubers (Purnima and Srivastava, 1988). Visible buds are present unlike in D. floribunda and D. composita where the buds are confined to the crown position (Selvaraj et al, 1972).

Importance of Diosgenin: Diosgenin is the most important sapogenin used as a starting material for synthesis of a number of steroidal drugs. For commercial purposes, its -isomer, yamogenin is also taken as diosgenin while analysing the sample for processing. Various steroidal drugs derived from diosgenin by artificial synthesis include corticosteroids, sex hormones, anabolic steroids and oral contraceptives. Corticosteroids are the most important group of steroidal drugs synthesized from diosgenin. First group of corticosteroids regulates carbohydrate and protein metabolism. The second group consists of aldosterone, which controls balance of potassium, sodium and water in the human body. The glucocorticoids in the form of cortisone and hydrocortisone are used orally, intramuscularly or topically for treatment of rheumatoid arthritis, rheumatic fever, other collegen diseases, ulcerative colitis, certain cases of asthma and a number of allergic diseases affecting skin, eye and the ear. These are also used for treatment of gout and a variety of inflammations of skin, eye and ear and as replacement therapy in Addison’s diseases. The minerato corticoides, desoxycorticosterone or desoxycortone are used in restoring kidney functions in cases of cortical deficiency and Addison’s disease.

Both male and female sex hormones are also synthesized from disosgenin. The main male sex hormone (androgen) which is produced from disogenin is testosterone. The main female sex hormones produced are oestrogen and progesterone. Recently oestrogen has also been used in cosmetic lotions and creams to improve the tone and colour of skin. One of the main uses of progesterone during recent years has been as antifertility agent for oral contraceptives. These artificial steroids have increased oral activity and fewer side effects, as they can be used in reduced doses. Oral contraceptives are also used for animals like pigs, cows and sheep to control fertility and to give birth at a prescribed period in a group of animals at the same time. These compounds are also used to reduce the interval between the lactation periods to have more milk and meat production. Anti-fertility compounds are also used as a pest-control measure for decreasing the multiplication of pests like rodents, pigeons and sea gulls (Husain et al, 1979).

Although yam tubers contain a variety of chemical substances including carbohydrates, proteins, alkaloids and tannins, the most important constituents of these yams are a group of saponins which yield sapogenins on hydrolysis. The most imp ortant sapogenin found in Dioscorea are diosgenin, yamogenin and pannogenin. Diosgenin is a steroid drug precursor. The diogenin content varies from 2-7% depending on the age of the tubers. Saponins including 5 spirastanol glucoside and 2 furostanol glucoside, 4 new steroid saponins, floribunda saponins C, D, E and F. Strain of A and B are obtained from D. floribunda (Husain et al, 1979). Rhizomes of D. deltoidea are a rich source of diosgenin and its glycoside. Epismilagenin and smilagenone have been isolated from D. deltoidea and D. prazeri (Chakravarti et al, 1960; 1962). An alkaloid dioscorine has been known to occur in D. hispida (Bhide et al,1978). Saponin of D. prazeri produced a fall of blood pressure when given intravenously and saponin of D. deltoidea has no effect on blood pressure (Chakravarti et al,1963). Deltonin, a steroidal glycoside, isolated from rhizomes of D. deltoidea showed contraceptive activity (Biokova et al, 1990).

Agrotechnology: Dioscorea species prefer a tropical climate without extremity in temperature. It is adapted to moderate to heavy rainfall area. Dioscorea plants can be grown in a variety of soils, but light soil is good, as harvesting of tubers is easier in such soils. The ideal soil pH is 5.5-6.5 but tolerates fairly wide variation in soil pH. Dioscorea can be propagated by tuber pieces, single node stem cuttings or seed. Commercial planting is normally established by tuber pieces only. Propagation through seed progeny is variable and it may take longer time to obtain tuber yields. IIHR, Bangalore has released two improved varieties, FB(c) -1, a vigorously growing strain relatively free from diseases and Arka Upkar, a high yielding clone. Three types of tuber pieces can be distinguished for propagation purpose, viz. (1) crown (2) median and (3) tip, of which crowns produce new shoots within 30 days and are therefore preferred. Dipping of tuber pieces for 5 minutes in 0.3% solution of Benlate followed by dusting the cut ends with 0.3% Benlate in talcum powder in mo ist sand beds effectively checks the tuber rot. The treatment is very essential for obtaining uniform stand of the crop. The best time of planting is the end of April so that new sprouts will grow vigorously during the rainy season commencing in June in India. Land is to be prepared thoroughly until a fine tilth is obtained. Deep furrows are made at 60cm distance with the help of a plough. The stored tuber pieces which are ready for planting is to be planted in furrows with 30cm between the plants for one year crop and 45cm between the plants for 2 year crop at about 0.5 cm below soil level. The new sprouts are to be staked immediately. After sprouting is complete, the plants are to be earthed up. Soil from the ridges may be used for earthing up so that the original furrows will become ridges and vice versa. Dioscorea requires high organic matter for good tuber formation. Besides a basal doze of 18-20t of FYM/ha, a complete fertilizer dose of 300kg N, 150kg P2O5 and K2O each are to be applied per hectare. P and K are to be applied in two equal doses one after the establishment of the crop during May-June and the other during vigorous growth period of the crop (August- September). Irrigation may be given at weekly intervals in the initial stage and afterwards at about 10 days interval. Dioscorea vines need support for their optimum growth and hence the vines are to be trailed over pandal system or trellis. Periodic hand weeding is essential for the first few months. Intercropping with legumes has been found to smother weeds and provide extra income. The major pests of Dioscorea are the aphids and red spider mites. Aphids occur more commonly on young seedlings and vines. Young leaves and vine tips eventually die if aphids are not controlled. Red spider mites attack the underside of the leaves at the base near the petiole. Severe infestations result in necrotic areas, which are often attacked by fungi. Both aphids and spider mites can be very easily controlled by Kelthane. No serious disease is reported to infect this crop. The tubers grow to about 25-30 cm depth and hence harvesting is to be done by manual labour. The best season for harvesting is Feb-March, coinciding with the dry period. On an average 50-60t/ha of fresh tubers can be obtained in 2 years duration. Diosgenin content tends to increase with age, 2.5% in first year and 3-3.5% in the second year. Hence, 2 year crop is economical (Kumar et al, 1997).... medicinal yams

(Welsh) Form of Margaret, meaning “resembling a pearl / the child of light” Maegan, Meg, Magan, Magen, Megin, Maygan, Meagan, Meaghan, Meagin, Meeghan, Meegan, Meghan, Megdn, Meggen, Megen, Meggan, Meggie, Meggy, Meganira, Meighan... megan

Buch.-Ham ex Wight.

Family: Asclepiadaceae.

Habitat: Sub-Himalayas tract from Uttar Pradesh to Meghalaya and in central and Peninsular India.

Ayurvedic: Go-chandanaa.

Action: Toxic. Used as a substitute for Cephaelis ipecacuanha as emetic, purgative and febrifuge; externally on unhealthy ulcers and wounds.... tylophora fasciculata

DC.

Synonym: V. arborea Hook. f. non- Buch.-Ham.

Family: Compositae; Asteraceae.

Habitat: West Bengal, Assam, Meghalaya and Western Ghats.

Siddha/Tamil: Shutthi.

Action: Bark—febrifuge. The bark is chewed as a substitute for betel leaves.... vernonia javanica

Roxb.

Synonym: A. malaccensis Lamk.

Family: Thymelaceae.

Habitat: The hills of Assam, Meghalaya, Nagaland, Manipur and Tripura.

English: Aloewood, Eaglewood, Agarwood.

Ayurvedic: Aguru, Krimij, Krish- naaguru, Jongaka, Maaliyaka, Loha, Kaalaloha, Asitaka.

Unani: Ood-ul Hindi, Ood Gharqi.

Siddha/Tamil: Akil kattai, Agil.

Action: Heartwood—astringent, carminative, antiasthmatic, anti- diarrhoeal, antidysenteric; used in gout, rheumatism and paralysis; as a stimulant in sexual debility; as a liniment in skin diseases.

The agarwood or eaglewood of commerce is derived from the fungus- infected tree through wounds caused by the species of Aspergillus, Fusarium, Penicillium, and also by some of Fungi Imperfecti. Agarwood on distillation yields an essential oil, known as Agar Oil.

The essential oil yields a number of agarofurans, sesquiterpene alcohols and spirosesquiterpene alcohols.

The stemwood yields sesquiterpe- noids—gmelofuran and agarol; also a coumarinolignan—aquillochin.

(Agar is a different drug—extract of a seaweed, Gelidium Amansii, used as a mild laxative.)

Dosage: Heartwood—1-3 g powder. (API Vol. IV.)... aquilaria agallocha

(L.) Correa.

Synonym: A. floribunda Wt.

Family: Rutaceae.

Habitat: Throughout India, especially in Assam, Meghalaya and Andaman Islands.

English: Wild Lime.

Siddha/Tamil: Kattu Narangam, Kattu Elumichai.

Folk: Jungli Nimbu.

Action: Oil from leaves and berry— antibacterial, antifungal. Leaves— a decoction is applied to cutaneous affections. Fruit—juice, antibilious.... atalantia monophylla

Roxb. var. nepalensis A. DC.

Family: Begoniaceae.

Habitat: Tropical and sub-tropical regions, especially in America. Found in Sikkim, Arunachal Pradesh, Assam, Meghalaya, Nagaland and Manipur, ascending to an altitude to 2,100 m.

English: Beefsteak Geraniums, Elephant's Ear.

Folk: Hooirjo (West Bengal), Teisu (Nagaland).

Action: A decoction of the root is given for liver diseases and fever. The extract from succulent stalks is used for venereal diseases in folk medicine. Fresh shoots are chewed for tooth troubles. Aqueous extracts of the leaves and flowers of Begonia sp. are active against Gram-positive and Gram-negative bacteria.

Hooirjo and Teisu are also equated with B. palmata D. Don var. gamblei Hara, found in northeastern regions of India.... begonia laciniata

Linn.

Family: Cyperaceae.

Habitat: Throughout India, as a weed upto 2,000 m.

English: Nut Grass.

Ayurvedic: Musta, Mustaa, Mus- taka, Abda, Ambuda, Ambhoda, Ambodhara, Bhadra, Bhadraa, Bhadramusta, Bhadramustaa, Bhadramustaka, Ghana, Jalada, Jaldhara, Meghaahvaa, Nirada, Vaarida, Vaarivaaha, Payoda, Balaahaka. Ganda-Duurvaa (var.).

Unani: Naagarmothaa, Saad-e-Kufi.

Siddha/Tamil: Koraikkizhangu.

Folk: Mothaa.

Action: Carminative, astringent, anti-inflammatory, antirheumat- ic, hepatoprotective, diuretic, antipyretic, analgesic, hypoten- sive, emmenagogue and nervine tonic.

Used for intestinal problems, indigestion, sprue, diarrhoea, dysentery, vomiting and fever; also as a hypoc- holesterolaemic drug and in obesity.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicated the use of the rhizome in rheumatism, inflammations, dysuria, puerperal diseases and obesity.

The tuber is rich in Cu, Fe, Mg and Ni. Beta-sitosterol, isolated from the tubers, exhibits significant anti- inflammatory activity against carra- geenan- and cotton pellet-induced oedema in rats; the activity is comparable to hydrocortisone and phenylbutazone when administered intraperi- toneally.

The alcoholic and aqueous extracts of the tubers possess lipolytic action and reduce obesity by releasing enhanced concentrations of biogenic amines from nerve terminals of the brain which suppress the appetite centre. Presence of eudalne group of ses- quiterpenic compounds of sesquiter- pene alcohol, isocyperol is said to play an important role in lipid metabolism.

An alcoholic extract of the plant exhibits liver-protective activity against CCL4-induced liver damage in mice.

Methanolic extract of the plant stimulates the production of melanin in cultured melanocytes. (Plant extract is used in preparations used for pigmentation of skin and hair, also in suntan gels.) Aqueous-alcoholic extract of the tuber exhibited hypotensive, diuretic, antipyretic and analgesic activities. These are attributed to a triterpenoid.

The essential oil (0.5-0.9%) from the tubers contains mainly sesquiterpenes.

C. platystilis Br. is equated with Kaivarta-mustaka.

Dosage: Rhizome—3-6 g powder; 20-30 ml decoction. (API Vol. III.)... cyperus rotundus

Costus speciosus

Zingiberaceae

San: Pushkara, Kashmeera, Kemuka;

Hin: Kebu, Keyu, Kust;

Ben: Keu, Kura

Mal: Channakkizhangu, Channakoova;

Tam: Kostam; Mar: Penva;

Tel: Kashmeeramu

Importance: Costus is one of the plants which contains diosgenin in its rhizome. It is widely used as starting material in the commercial production of steroidal hormones. The rhizomes are useful in vitiated conditions of kapha and pitta, burning sensation, flatulence, constipation, helminthiases, leprosy, skin diseases, fever, hiccough, asthma, bronchitis, inflammation and aneamia. It is used to make sexual hormones and contraceptives (Warrier et al,1994).

Distribution: The plant is widely distributed in Asia and other tropical countries like India, Nepal, Pakistan, Sri Lanka and China. In India, it occurs mostly in Arunachal Pradesh, Meghalaya, Nagaland, Tamil Nadu, Assam, Tripura and Kerala.

Botany: Costus speciosus (Koenig.) Sm. belonging to the family Zingiberaceae consists of two varieties viz., var. nepalensis Rose., found only in Nepal and Arunachal Pradesh and var. argycophyllus Wall., having a wide distribution in India.

The plant is a succulent herb with long leafy spirally twisted stems, 2-3m in height and horizontal rhizomes. Leaves are simple, spirally arranged, oblanceolate or oblong, glabrous above, silky pubescent beneath with broad leaf sheaths. Flowers are white, large, fragrant, arranged in dense terminal spikes. Bracts are bright red. The single stamen present is perfect, lip large with incurved margins. Fruits are globose or ovoid capsules with obovoid or sub- globose seeds (Warrier et al,1994).

Agrotechnology: Costus can be raised under a wide range of agroclimatic conditions. It prefers sandy loam soil for good growth. Propagation is by rhizomes. The best season for planting is April- May. The seed rate recommended is 2-2.4t/ha. The spacing adopted is 50x50cm. After an initial ploughing FYM or poultry manure should be applied at the rate of 30t/ha and the field is to be ploughed again irrigated and prepared to obtain a fine seed bed. Furrows are opened and the rhizome pieces are placed horizontally at a depth of 8-10cm and covered with soil. Care is taken to place the eye buds facing upwards. After 70-75 days about 90-95% sprouting is obtained. Desiccation of the young sprouts have been observed in the hot summer months, necessitating liberal water supply during the period. As September-November is the period of maximum tuberization at least two irrigations should be given at that time. One during the sprouting period of the crop followed by two more keeps the crop fairly free of weeds. Application of 37t/ha of poultry manure and fertilizers, 60kg P2O5 and 40kg K2O /ha as a basal doze, along with 80kg N/ha applied in 3 equal split dozes will take care. Crop is harvested at the end of seven months. Harvesting includes 2 operations, cutting the aerial shoots and digging out the rhizomes. Cost of production of diosgenin ranges from Rs. 271-300/kg (Atal, et al,1982).

Properties and activity: Tubers and roots contain diosgenin, 5 -stigmast-9(11)-en-3 ol, sitosterol- -D- glucoside, dioscin, prosapogenins A and B of dioscin, gracillin and quinones. Various saponins, many new aliphatic esters and acids are reported from its rhizomes, seeds and roots. Seeds, in addition, contain - tocopherol. Saponins from seeds are hypotensive and spasmolytic. Rhizomes possess antifertility, anticholinestrase, antiinflammatory, stimulant, depurative and anthelmintic activities (Hussain et al, 1992).... costus

Markgraf.

Synonym: G. scandens Roxb. in part.

Family: Gnetaceae.

Habitat: Tropical Himalayas from Nepal to Bhutan, Assam and Meghalaya.

English: Joint Fir.

Siddha/Tamil: Anapendu, Peiodal (G. ula.)

Action: Seed oil—antirheumatic. Plant— antiperiodic. Leaves— piscic.

The stem-wood yielded bergenin, acetophenone and stilbene derivatives.

G. ula Brongn. non-Karst is found in evergreen forests of Western and Eastern Ghats up to 1,800 m.... gnetum montanum

(Blume) DC.

O. stolinifera Wall. ex

Family: Apiaceae; Umbelliferae.

Habitat: Marshy places and river banks in North India from Kashmir to Assam.

Folk: Jateraa (Meghalaya); Pan- turasi (Bengal).

Action: The plant extract showed strong antimutagenic and antitu- mour activity.

From the herb, beta-sitosteryl gluco- side, stigmasteryl glucoside, isorham- netin and hyperin were isolated. The fruit yield 1.5% of an essential oil, containing phellandrene and myristicin.

Linalool (70.0%) was determined in the flower oil.

Evening Primrose is equated with Oenothera biennis L. (native to North America). The oil from seeds, known as Evening Primrose oil, contains about 70% cis-linolenic acid and about 9% cis-gamma-linolenic acid (GLA). Evening Primrose oil is one of the most widely prescribed plant-derived medicines in the world. Sold under the trade name Epogam, it is recognized by the governments of Great Britain, Germany, Denmark, Ireland, Spain, Greece, South Africa, Australia and New Zealand as a treatment for eczema. A combination, known as Efamol Marine, used for eczema, contains 80% Evening Primrose Oil and 20% fish oil.

Evening Primrose Oil has become a frontline treatment in Great Britain for initial treatment of cyclical breast pain and fibrocystic breast disease.... oenanthe javanica

Falc.

Family: Asclepiadaceae.

Habitat: The Himalayas, from Kashmir to Nepal and Meghalaya, ascending to 1,800 m.

Ayurvedic: Krishna Saarivaa (substitute). (Cryptolepis buchanani is equated with Krishna Saarivaa.)

Action: Used in place of Cryptolepis buchanani and Hemidesmus indicus for rheumatism, urinary and skin diseases.

The glycosides locin, plocin, ploci- nin, calocin, calocinin, as well as triter- penoids, have been reported from the twigs.... periploca calophylla

Nees.

Family: Acanthaceae.

Habitat: The sub-tropical Himalayas, Upper Gangetic Plain, Bihar, North Bengal and Assam.

Folk: Dieng-soh kajut (Meghalaya), Chuhai (Bihar), Titaaphul (Assam).

Action: Whole plant—used like Adhatoda vasica in whooping cough and menorrhagia. Fruits and leaves—burnt and prescribed for fevers. The leaves are reported to contain diterpene lactone, phlogantholide A and its glucoside.

A related species, P. jenkinsii C. B. Clarke, found in Assam, is also known as Titaaphul. A decoction of leaves is given for diseases of spleen and liver and for fevers.... phlogacanthus thyrsiflorus

Nees.

Synonym: S. cusia (Nees) Imlay.

Family: Acanthaceae.

Habitat: Assam, Meghalaya, West Bengal and Manipur.

English: Assam Indigo.

Folk: Ruum, Raampat (Assam); Khumaa (Manipur).

Action: Leaves—astringent, diuretic and lithotriptic.

The indican content of the leaves has been reported to be 0.4-1.3%. Lupe- ol, betulin, lupenone, indigo, indiru- bin, a quinazolinone and a quinazo- linedione have been isolated.... strobilanthes flaccidifolius

Hook. f.

T. lucidum (D. Don) K.

Family: Apocynaceae.

Habitat: Temperate and subtropical Himalaya from Kumaon to Arunachal Pradesh and in Assam, Meghalaya up to 2,100 m.

Folk: Duudhi (Kumaon), Akhaahi- lataa (Assam).

Action: Used as a substitute for Alstonia scholaris.

T. jasminoides Lem. (Star-Jasmine), native to China and Japan, is cultivated all over India. Alkaline extracts of the leaf and stem show activity against yeast. The leaves and twigs contain dambonitol, cyclitol, arctiin, tracheloside, beta-amyrin and its acetate, lu- peol acetate, and a mixture of beta- stosterol, stigmasterol and campes- terol. A flavone glycoside was isolated from the butanol extract of dried leaves and several indole alkaloids from the alcoholic extract of dried leaves and twigs.

The leaves, stem and twigs are used for treating rheumatic arthritis, nervous disorders, urine retention and as a tonic for weak muscles or nerves.... trachelospermum fragrans

Linn.

Family: Cucurbitaceae.

Habitat: The peninsular India, khasi hills of Meghalaya and the Andamans.

Ayurvedic: Chirpoti, Chirpotaa, Kuntali, Tiktaka.

Siddha/Tamil: Penar-valli.

Folk: Parpoti.

Action: Fruits—cathartic, used for cough and asthma. Leaves— antispasmodic; topically applied to reduce inflammation and irritation. Plant—febrifuge.

Synonym: Richardia africana Kunth.

Family: Araceae.

Habitat: Cooler parts of Bihar and Orissa.

Action: Leaves—used as a poultice on sores, boils, wounds, burns, insect-bites and on painful parts of gout and rheumatism.

The plant contains an acrid juice which is poisonous and irritant; irritation is caused by raphides of calcium oxalate. A toxic principle has been reported from the inflorescence, spathe and flower stem. It produced effect in rabbits ranging from hypo-aesthesia to paralysis.

The flowers contain cytokinin along with swertisin, swertiajaponin, cyani- din, peonidin and ferulic acid.

Roasting and boiling appear to destroy the toxicity of leaves.... zanonia indica

Wall. ex DC.

Synonym: Z. limonella (Dennst.) Alston. Z. rhetsa DC. Fagara budrunga Roxb. F. rhetsa Roxb.

Family: Rutaceae.

Habitat: Meghalaya, foothills of Assam and Peninsular India.

Ayurvedic: Tumburu (Kerala), Ashvaghra, Tejabala.

Siddha/Tamil: Tratechai.

Action: Fruits—used for diarrhoea, dyspepsia; asthma, bronchitis; rheumatism; diseases of the mouth and teeth. Pericarp—astringent, digestive, stimulant. Essential oil—disinfectant, used in infective dermatosis. Bark—cholinergic, diuretic, hypoglycaemic, spasmolytic. Root—emmenagogue, febrifuge.

The trunk-bark from Assam gave alkaloids—chelerythrine (0.014%), evodiamine (0.03%) and hydoxyevodi- amine (0.05%). The essential oil from the fruit contains l-sabinene, alpha- terpinene, beta-phellandrene, 1,4-cine- ole, decanal, octanal, terpinen-4-ol, dihydrocarveol, l-cryptone and cumi- naldehyde.

The essential oil exhibits anti-inflammatory, anaesthetic and antago- nisic activity.

Z. nitidum (Roxb.) DC. (Bihar eastwards to Sikkim and Assam) is known as Tezmul in Assam. The root is used in toothache and stomachache.

The plant is used as one of the ingredients in the preparation of pharmaceutical tablets given to drug addicts for the treatment of withdrawl symptoms.

Methanolic extract of the roots gave nitidine, chelerythrine and isogari- dine. The extract showed antitumour property.

Z. ovalifolium Wight (Eastern Himalayas, Meghalaya, the Western Ghats of South Kanara and Kerala) is known as Armadalu in Karnataka and Diang-shih in Meghalaya (Khasi Hills). The leaf contains diosmetin and the heartwood contains flavonoids of dihydrofisetin and cinnamaldehyde. The bark and fruit possess properties similar to other species of the genus.... zanthoxylum budrunga