Carried out as two separate exercises – one by a privately funded American team; another by an international joint venture between tax-funded American laboratories, a charitably funded British one and several other smaller research teams from around the world – the ?rst results were announced on 26 June 2000. In February 2001 the privately funded American group, known as Celera Genomics, announced that it had identi?ed 26,558 genes. At the same time the Human Genome Project consortium reported that it had identi?ed 31,000. Allowing for margins of error, this gives a ?gure much lower than the 100,000 or more human genes previously forecast by scientists. Interestingly, genes were found to make up only 3 per cent of the human genome. The remaining 97 per cent of the genome comprises non-coding DNA which, though not involved in producing the protein-initiating genetic activity, does have signi?cant roles in the structure, function and evolution of the genome.
One surprise from the Project so far is that the genetic di?erences between humans and other species seem much smaller than previously expected. For example, the Celera team found that people have only 300 genes that mice do not have; yet, the common ancestor of mice and men probably lived 100 million years or more in the past. Mice and humans, however, have around twice as many genes as the humble fruit ?y.
Cells die out when they become redundant during embryonic development: genes also die out during evolution, according to evidence from the Genome Project – a ?nding that supports the constant evolutionary changes apparent in living things; the Darwinian concept of survival of the ?ttest.
Apart from expanding our scienti?c knowledge, the new information – and promise of much more as the Genome Project continues – should enhance and expand the use of genetic engineering in the prevention and cure of disease. Studies are in progress on the gene for a receptor protein in the brain which will shed light on how the important neurotransmitter SEROTONIN in the brain works, and this, for example, should help the development of better drugs for the treatment of DEPRESSION. Another gene has been found that is relevant to the development of ASTHMA and yet another that is involved in the production of amyloid, a complex protein which is deposited in excessive amounts in both DOWN’S (DOWN) SYNDROME and ALZHEIMER’S DISEASE.... human genome
Air hunger is an instinctive craving for oxygen resulting in breathlessness, either when a person ascends to great heights where the pressure of air is low, or in some diseases such as pneumonia and DIABETES MELLITUS which affect the body’s METABOLISM and therefore its need for oxygen – an essential constituent in this process.... hunger
There are over 50 strains of human papillomavirus.
Infection with some of these strains is thought to be a causative factor in cervical cancer and anal cancer.... human papillomavirus
The chorea usually affects the face, arms, and trunk, resulting in random grimaces and twitches, and clumsiness. Dementia takes the form of irritability, personality and behavioural changes, memory loss, and apathy.
At present, there is no cure for Huntington’s disease, and treatment is aimed at reducing symptoms with drugs.... huntington’s disease
Affected children may appear normal at birth but, at 6–12 months of age, they develop cardiac abnormalities, umbilical hernia, skeletal deformities, and enlargement of the tongue, liver, and spleen.
Growth is limited and mental development slows.
If the condition is diagnosed in early infancy, a bone marrow transplant may be curative.... hurler’s syndrome
The vitreous humour consists almost entirely of water.... vitreous humour
Hooda, Hudah, Hoodah, Houda, Houdah... huda
Hudsen, Hudsan, Hudsun, Hudsyn, Hudsin... hudson
Habitat: Konkan and North Kanara, throughout dry forests of Tamil Nadu.
Folk: Kaakibeeraa, Kansamaara.Siddha/Tamil: Agori. Motirakkanni.Action: Root—anti-inflammatory, febrifuge; disperses swellings.... hugonia mystax
course of the week. (See also LEGIONNAIRE’S DISEASE.)... humidifier fever
Humitah, Humyta, Humeeta, Humieta, Humeita, Humeata, Humytah, Humeetah, Humietah, Humeitah, Humeatah... humita
Humidity is expressed as relative humidity (RH). This is the amount of moisture in the air expressed as a percentage of the maximum possible at that temperature. If the temperature of a room is raised without increasing the moisture content, the RH falls. The average outdoor RH in Britain is around 70–80 per cent; with central heating it may drop to 25 per cent or lower. This is why humidi?cation, as it is known, of the air is essential in buildings heated by modern heating systems. The aim should be to keep the RH at around 30–50 per cent. In houses this may be achieved quite satisfactorily by having a jug or basin of water in the room, or some receptacle that can be attached to the heater. In o?ces, some more elaborate form of humidi?er is necessary. Those suffering from chronic BRONCHITIS are particularly susceptible to dry air, as are those individuals with disorders of the EYE because the secretions that bathe the eyes and keep them moist are unnaturally dried out. (See also VENTILATION.)... humidification
Habitat: Native to Europe and Asia. Conditions for its successful cultivation are reported to exist in Kashmir and parts of Himachal Pradesh.
English: Hops.Unani: Hashish-ut-Dinaar.Action: Flowers—sedative, hypnotic, nervine tonic, diuretic, spasmolytic on smooth muscle, analgesic, astringent. Used for nervous diseases, intestinal cramps, menopause, insomnia, neuralgia and nervous diarrhoea. Also as a tonic in stomach and liver affections. As a blood cleanser, the root is used like sarsaparilla.
Key application: In mood disturbances, such as restlessness and anxiety, sleep disturbances. (German Commission E. ESCOP.)The British Herbal Compendium and The British Herbal Pharmacopoeia reported herb's action as sedative, soporific, spasmolytic and aromatic bitter, and indicated its use for excitability, restlessness, disorders of sleep and lack of appetite.Hop cones consist of the whole dried female inflorescences of Humu- lus lupulus.Hop contains bitter principles— lupulin containing humulon, lupulon and valerianic acid; volatile oil (0.31.0%) including humulene; flavonoids including xanthohumole; polypheno- lic tannins, asparagin, oestrogenic substances.Bitter principles stimulate the digestive system. Valerianic acid is sedative. The resin components, lupulon and humulon are antiseptic against Grampositive bacteria. Asparagin is diuretic. Research suggested that the anti- spasmodic effect is stronger than the sedative, and hops also possess antihis- taminic and anti-oxytocic properties. (Cases of amenorrhoea and dysmen- orrhoea are treated with hops.)Hop extracts exert different effects on CNS in mice. They show hypother- mic, hypnotic, sedative, muscle relaxing and spontaneous locomotor activities, besides potentiating pentobarbital anaesthesia in mice.Humulone inhibited induced inflammation in mice.The dried strobila containing humu- lone and lupulone showed antidiabetic activity in experimental rats.Hop mash or extract is used in the preparation of toothpaste for inhibiting Gram-positive bacteria and in hair preparations for preventing dandruff formation. It is also used in skin- lightening creams.... humulus lupulusHuriya, Huriyyah, Hooriya, Huriyya, Hooriyah... huriyah
Hutenah, Hutenna, Hutyna, Hutina... hutena
Habitat: Native to tropical America; introduced into India.
English: Sandbox tree, Monkey Dinner-bell.Siddha/Tamil: Mullarasanam.Action: Seed, bark and fresh latex— emetocathartic, antileprotic. Seed— insecticidal, piscidal.
In South America, a poultice made from the latex is used for treating cutaneous leishmaniasis. Highly irritant and tumour-promoting deterpene esters (DTC) have been detected in the latex. Latex gave the triterpenes, 24- methylene cycloartanol, cycloartanol and butyrospermol. Sap of the plant gave a diterpene hexaol ester, huratox- in, and a glycolipoprotein, crepitin.... hura crepitansHuyanna, Huyane, Huyann, Huyanne... huyana
Habitat: Sub-tropical Himalayas from Kashmir to Nepal and in the Nilgiris, Palni Hills, Western Ghats and Kerala.
English: Yellow Jasmine, Nepal Jasmine, Italian Jasmine.Ayurvedic: Svarna-yuuthikaa, Svarnajaati, Hemapushpikaa, Vaasanti.Siddha/Tamil: Semmalligai.Folk: Juuhi (yellow var.).Action: Flower—astringent, cardiac tonic. Root—used in ringworm. The milky juice, exuded from incisions in the bark, is used for treating chronic fistulas. The plant is also used for treating hard lumps.
The leaves gave alpha-amyrin, be- tulin, friedelin, lupeol, betulinic, olea- nolic and ursolic acids; beta-sitosterol, 10-cinnamoyloxyoleoside-7-methyl- ester (jasminoside) and a secoiridoid glycoside.... jasminum humileHabitat: Native to warmer parts of America; introduced into Indian gardens.
English: Baby Pepper, Dog Blood, Blood Berry, Rouge-Plant.Action: Berries—febrifuge, intestinal antiseptic.
A betaxanthin, humilixanthin, has been isolated from the berry.A decoction of the herb is used for cold, chest congestion and pain, diarrhoea and jaundice. Berries alleviate dysentery and amenorrhoea.Pounded leaves are used for wound- healing and for treating catarrh.... rivina humilisKeynote: kidneys. Part used: pods without beans.
Action: hypotensive, diuretic, anti-diabetic, resolvent, glycaemic – to regulate blood sugar.
Uses: Water retention. Albuminuria (proteinuria), especially of pregnancy. Oedema of cardiac origin. Premenstrual tension. Diabetes mellitus. Hyperinsulinism. To induce loss of weight. Swollen legs and ankles. Hypoglycaemia. Sometimes given in combination with Bladderwrack.
Preparations: Capt Frank Roberts Bean Cure. 40 grams of the dried herb soaked for 6 hours in 750ml (1 and a half pints) cold water. Boil, half an hour. Drink all over 1-2 days for water retention.
Roasted beans: nutritious coffee substitute.
French bean water (after cooking beans without salt) used traditionally in France for a soaked-lint compress for leg ulcer.
Powder. Capsules, 200mg. Dose: 8 capsules: 2 in morning, 3 at midday, 3 in the evening, at beginning of meals. (Arkocaps) ... bean husks
Action. Anti-infective against Coxsackie virus. Immune stimulant. Antiviral.
Uses: Myalgic encephalomyelitis (ME). Upper respiratory infection. For increased white blood cell count, improved sleep habits and to stimulate appetite in patients receiving chemotherapy and radiation. (American Health 1989 8th Oct. –100) To increase production of interferon. Gastric ulcer therapy. Influenza. The common cold. To combat Coxsackie B myocarditis. Of value for incontinence and frequency of urine. Inhibits HIV-1 replication in cells acutely or chronically infected.
Preparation. Decoction. Dried root: 2 teaspoons to each cup of water simmered gently 20 minutes. Half- 1 cup thrice daily. ... huang qi
Differential diagnosis: arterio-sclerosis, Sydenham’s chorea.
Action. Emotional instability ranging from apathy to irritability. Complicated by menstrual problems (Motherwort, Helonias, Black Cohosh). Regresses into dementia. No cure possible, but anti-convulsants may reduce contortions and restlessness. Institutional care may be necessary. Scientists claim the gene that causes Huntingdon’s disease has been identified.
Alternatives. Of Therapeutic Value. Betony, Black Cohosh, Chamomile (German), Cramp bark, Helonias, Ladyslipper, Motherwort, Oats, Passion flower, Sarsaparilla, Skullcap, Valerian, Feverfew. Tablets/capsules. Motherwort, Passion flower, Skullcap, Valerian.
Formula. Combine: equal parts, Black Cohosh, Mistletoe, Helonias. Dose: Powders: 500mg (two 00 capsules or one-third teaspoon). Liquid extract: 1 teaspoon. Tinctures: 2 teaspoons. Thrice daily in water or honey.
Traditional, UK. Combine equal parts, Skullcap, Valerian, Mistletoe. 1oz (30g) to 1 pint (500ml) water; bring to boil; remove vessel when boiling point is reached. Dose: half-1 cup thrice daily.
Diet. Lacto-vegetarian. Yoghurt. Low salt. Oatmeal porridge, Muesli, regular raw food days. Supplements. Vitamin B-complex, Vitamin B6, Kelp, Calcium, Magnesium, Zinc.
Note: It would appear the Ginkgo would be an object of scientific study for the complaint. Treatment by or in liaison with general medical practitioner only. ... huntingdon’s chorea
The term humours usually refers to the aqueous humour and vitreous humour that occur in the eye.... humours