The sum total of changes in an organism in order to achieve a balance (homeostasis). Catabolic burns up, anabolic stores and builds up; the sum of their work is metabolism.... metabolism
A generally slow growing malignant epithelial tumour, which has potential to invade and metastasise, especially if untreated.... basal cell carcinoma
The basic rate of combustion by a person, usually measured after sleep and while resting.... basal metabolism
At or near the base, such as leaves sprouting directly from root or crown.... basal
Grey matter near the base of the cerebral hemispheres, consisting of the corpus striatum (caudate nucleus and lenticular nucleus [globus pallidus and putamen]), claustrum, and amygdaloid nucleus (see BRAIN). The basal ganglia are involved in the subconscious regulation of voluntary movement, and disorders in this region cause DYSKINESIA.... basal ganglion
A process by which the body destroys and excretes drugs, so limiting their duration of action. Phase 1 metabolism consists of transformation by oxidation, reduction, or hydrolysis. In phase 2 this transformed product is conjugated (joined up) with another molecule to produce a water-soluble product which is easier to excrete.... drug metabolism
a process in which a drug administered by mouth is absorbed from the gastrointestinal tract and transported via the portal vein to the liver, where it is metabolized. As a result, in some cases only a small proportion of the active drug reaches the systemic circulation and its intended target tissue. First-pass metabolism can be bypassed by giving the drug via sublingual or buccal routes.... first-pass metabolism
any one of a group of inherited conditions in which there is a disturbance in either the structure, synthesis, function, or transport of protein molecules. There are over 1500 inborn errors of metabolism; examples are *phenylketonuria, *homocystinuria, and *hypogammaglobulinaemia.... inborn error of metabolism