National Screening Committee website: contains detailed notes on all screening programmes the committee has considered and the rationale for the decisions the committee has made
National Screening Committee website: contains detailed notes on all screening programmes the committee has considered and the rationale for the decisions the committee has made
Genetic screening is proving to be a controversial subject. Arguments are developing over whether the results of such screenings should be made available to employers and insurance companies – a move that could have adverse consequences for some individuals with potentially harmful genetic make-ups. (See GENES; GENETIC DISORDERS.)... genetic screening
The most common – Local Research Ethics Committees (LRECs) – have provided a monitoring system of research on humans since the late 1960s. Established by NHS health authorities, LRECs were primarily perceived as exercising authority over research carried out on NHS patients or on NHS premises or using NHS records. Their power and signi?cance, however, developed considerably in the 1980s and 90s when national and international guidance made approval by an ‘appropriately constituted’ ethics committee obligatory for any research project involving humans or human tissue. The work of LRECs is supplemented by so-called ‘independent’ ethics committees usually set up by pharmaceutical companies, and since 1997 by multicentre research ethics committees (MRECs). An MREC is responsible for considering all health-related research which will be conducted within ?ve or more locations. LRECs have become indispensable to the conduct of research, and are doubtless partly responsible for the lack of demand in the UK for legislation governing research. A plethora of guidelines is available, and LRECs which fail to comply with recognised standards could incur legal liability. They are increasingly governed by international standards of practice. In 1997, guidelines produced by the International Committee on Harmonisation of Good Clinical Practice (ICH-GCP) were introduced into the UK. These provide a uni?ed standard for research conducted in the European Union, Japan and United States to ensure the mutual acceptance of clinical data by the regulatory authorities in these countries.
Other categories of ethics committee include Ethics Advisory Committees, which debate dif?cult patient cases. Most are attached to specialised health facilities such as fertility clinics or children’s care facilities. The 1990s have seen a greatly increased interest in professional ethics and the establishment of many new ethics committees, including some like that of the National Council for Hospice and Specialist Palliative Care Services which cross professional boundaries. Guidance on professional and ethical standards is produced by these new bodies and by the well-established ethics committees of regulatory or representative bodies, such as the medical and nursing Royal Colleges, the General Medical Council, United Kingdom Central Council for Nursing, Midwifery and Health Visiting, British Medical Association (see APPENDIX 8: PROFESSIONAL ORGANISATIONS) and bodies representing paramedics and professions supplementary to medicine. Their guidance ranges from general codes of practice to detailed analysis of single topics such as EUTHANASIA or surrogacy.
LRECs are now supervised by a central body
– COREC (www.corec.gov.org.uk).... ethics committees
NICE – its Scottish equivalent is the Scottish Health Technology Assessment Centre – has three main functions:
appraisal of new and existing technologies.
development of clinical guidelines.
promotion of clinical audit and con?dential inquiries. Central to its task is public concern about ‘postcode prescribing’ – that is, di?erent availability of health care according to geography.
In 2003 the World Health Organisation appraised NICE. Amongst its recomendations were that there should be greater consistency in the methods used for appraisal and the way in which results and decisions were reported. WHO was concerned about the need for transparency about the con?ict between NICE’s use of manufacturers’ commercial evidence in con?dence, and believed there should be greater de?nition of justi?cation for ‘threshold’ levels for cost-e?ectiveness in the Centre’s judgement of what represents value for money.
In all, WHO was congratulatory – but questions remain about the practical value and imlementation of NICE guidelines.... national institute for clinical excellence (nice)
Publications include: Hamdard Pharmacopoeia of Eastern Medicine; Greco-Arabian Concepts of Cardio-vascular Disease; Avicenna’s Tract of Cardiac Drugs and Essays on Arab Cardiotherapy. Scientific journal: Hamdard Medicus – informative articles by world authorities. Hamdard Foundation, Nazimabad, Karachi-18, Pakistan. ... hamdard national foundation, pakistan
Address: NHAA – PO Box 65, Kingsgrove, NSW 2208, Australia. Tel: +61(02) 502 2938. ... national herbalist association of australia
ULTRASOUND scanning is probably the most widely used diagnostic tool in obstetric practice. It can detect structural abnormalities such as SPINA BIFIDA and CLEFT PALATE and even cardiac and renal problems. A series of scans can assess whether the baby is growing at a normal rate; ultrasound may also be used to assist with other diagnostic tests (e.g. AMNIOCENTESIS – see below).
Tests on the mother’s blood can also diagnose fetal abnormalities. Alphafetoprotein (AFP) is produced by babies and ‘leaks’ into the AMNIOTIC FLUID and is absorbed by the mother. In spina bi?da and other neural-tube defects there is increased leakage of AFP, and a blood test at 16 weeks’ gestation can detect a raised level which suggests the presence of these abnormalities.
The triple test, also performed at 16 weeks, measures AFP and two hormones – HUMAN CHORIONIC GONADOTROPHIN and unconjugated OESTRADIOL – and is used in diagnosing DOWN’S (DOWN) SYNDROME.
Amniocentesis involves inserting a needle through the mother’s abdominal wall into the uterus to remove a sample of amniotic ?uid at 16–18 weeks. Examination of the ?uid and the cells it contains is used in the diagnosis of Down’s syndrome and other inherited disorders. The test carries a small risk of miscarriage.
Chorionic villus sampling may be used to diagnose various inherited conditions. A small amount of tissue from the developing PLACENTA is removed for analysis: this test has the advantages of having a lower incidence of miscarriage than amniocentesis and is carried out at an earlier stage (9–13 weeks).
Analysis of a blood sample removed from the umbilical cord (cordocentesis) may diagnose infections in the uterus, blood disorders or inherited conditions.
Direct observation of the fetus via a viewing instrument called a fetoscope is also used diagnostically and will detect structural abnormalities.
Most tests have a recognised incidence of false positive and negative results and are therefore usually cross-checked with another test. Counselling of the parents about prenatal tests is important. This allows them to make an informed choice which may not necessarily involve terminating the pregnancy if an abnormality is found. (See PREGNANCY AND LABOUR.)... prenatal screening or diagnosis
Sheila E. Drew BPharm PhD MRPharms. Deputy Head of Technical Services, William Ransom & Son plc.
Fred Fletcher-Hyde BSc FNIMH. President Emeritus, British Herbal Medicine Association. President Emeritus, National Institute of Medical Herbalists.
Simon Y. Mills MA FNIMH. Director, Centre for Complementary Health Studies, University of Exeter. Hugh W. Mitchell MNIMH (Hon). President, British Herbal Medicine Association. Managing Director, Mitchfield Botanics Ltd.
Edward J. Shellard BPharm PhD DSc(Hon) (Warsaw Medical Academy) FRPharmS CChem FRSC FLS. Emeritus Professor of Pharmacognosy, University of London.
Arnold Webster CChem MRSC. Technical Director, English Grains Ltd.
Peter Wetton BSc LRSC. G.R. Lane Health Products Ltd.
Hein Zeylstra FNIMH. Principal. School of Phytotherapy, Sussex. ... british herbal medicine association, scientific committee, 1995
(a) To promote and protect the interests of Health Foods Stores among members.
(b) To set standards in retailing of health foods and herbs.
(c) To encourage production, marketing and sales of products derived from purely natural and vegetable sources.
((d) To provide qualifications by certificate and diploma courses for those engaged in the industry.
The Association provides advice on aspects of health food and herb retailing and is able to help its members with professional advice and merchandising. NAHS Diploma of Health Food Retailing qualifies for membership of the Institute of Health Food Retailing. Address: Bastow House, Queens Road, Nottingham NG2 3AS. ... national association of health stores (nahs)
Members are directly involved with patient-care, carrying full responsibility for their recommendations, prescribing medication suitable to the individual biological requirements of each patient. Their role includes patient-counselling, health education and research.
Official recognition of the Institute, indicating its growing importance in the field of medicine came with the historic Grant of Arms by Her Majesty’s College of Heralds. Members regard this as evidence that the Royal Charter of King Henry VIII still stands and that there is no monopoly in healing the sick. See: HENRY VIII, HERBALISTS’ CHARTER.
The Institute played a major role in winning vital concessions for the survival of the herbalist in the passage through Parliament of the Medicine’s Bill. See: MEDICINE’S ACT, 1968.
In connection with the NIMH degree courses in herbal medicine are available at a London University, and Exeter University.
The Institute provides professional indemnity cover for its members, and is engaged in a series of clinical trials to evaluate traditional remedies.
All members are required to adhere to a strict professional Code of Ethics and are entitled to carry after their names the letters of qualification: MNIMH or FNIMH.
Members have a key role in preventative medicine and health promotion in their contribution to improvement of the nation’s health.
Address: 56 Longbrook Street, Exeter EX4 6AH, from which a list of members is obtainable. ... national institute of medical herbalists
Different arrangements apply in Northern Ireland, Wales, and Scotland.
NHS website: includes much basic medical information together with a guide to local services... national health service
NIHR website... national institute for health research
ONS website... office for national statistics