Tea for kidney Health Dictionary

Tea For Kidney: From 1 Different Sources


Consumption of tea can lead to many health benefits, as it is a natural beverage. There are various types of tea which help with kidney problems, as well. Find out more about teas for kidney! Why drink tea for kidney Damage of kidney (nephropathy) can lead to various problems. Some of the more common ones include kidney failure (also known as renal failure), kidney tumors (Wilms tumor or renal cell carcinoma), and kidney stones. Consumption of tea can help treat these problems, prevent them or slow down their progress. They also help maintain the kidneys in a healthy condition, which leads to other health benefits, such as regulating the blood pressure. Teas for kidney There are several types of tea which help with kidney problems. Most of them are herbal teas. Club moss tea, elderberry tea, saw palmetto tea, and cleavers tea have a cleansing effect, helping with the detoxification process. In the case of kidney failures, you can add centaury tea and Ceylon tea to your treatment. For other kidney problems, as well as the ones mentioned before, drink fenugreek tea, burdock tea, sassafras tea, banaba tea, sage tea, juniper tea, privet tea, orris tea, or milk thistle tea. Also, in order to have a pair of healthy kidneys, you can drink cranberry tea, goji tea, rehmannia tea, dandelion tea, lemongrass tea, or kukicha tea. Tea for kidney stones Kidney stones are some of the most common kidney problems. They are solid concretions or crystal aggregations which are formed in the kidneys and eliminated through urine. Black tea is one type of tea that can help with kidney stones. Other teas, herbal ones this time, are butterbur tea, corn silk tea, uva ursi tea, stone root tea, triphala tea, marshmallow tea, alfalfa tea, pipsissewa tea, and abuta tea. Tea for kidney side effects Side effects vary from one tea to another. Generally, it is recommended to speak to your doctor first, before consuming one of these teas, if you are pregnant or breastfeeding. Also, you have to be careful with black tea, which has a pretty high caffeine content. If your body can’t take caffeine, it might lead to unwanted side effects: headaches, nervousness, sleep problems, vomiting, diarrhea, irritability, irregular heartbeats, tremors, dizziness, or ringing in the ears. Teas you shouldn’t drink If you’ve got kidney problems, there are a few types of tea you should not drink. The list includes oolong tea, horse chestnut tea, lovage tea, wu yi tea, lemon verbena tea, rue tea, and periwinkle tea. Also, you might get kidney problems (even kidney stones) if you drink a high amount of boneset tea, yohimbe tea, yerba mate tea, essiac tea, parsley tea, osha tea, and meadowsweet tea. However, juniper tea and horsetail tea are part of a special class. They both help with kidney problems, but they have to be consumed properly. Over consumption can lead to kidney pains in the case of juniper tea, or kidney stones in the case of horsetail tea. You can protect your kidney, as well as treat various kidney problems, by drinking tea. Besides this, you’ll discover that, based on the type of tea you drink, you’ll get plenty of health benefits, as well. Have a cup of tea for kidney!
Health Source: Beneficial Teas
Author: Health Dictionary

Horseshoe Kidney

See KIDNEYS, DISEASES OF.... horseshoe kidney

Kidney Stone

Small, hard stone that may form in the kidneys and cause intense pain... kidney stone

Kidney Disorders

The kidneys are responsible for the excretion of many waste products, chiefly urea from the blood. They maintain the correct balance of salts and water. Any of the individual kidney disorders may interfere with these important functions. See: ABSCESS (kidney). BRIGHT’S DISEASE. CARDIAC DROPS. RENAL FLUID RETENTION. GRAVEL. HYDRONEPHROSIS. NEPHROSIS. PROTEINURIA. PYELITIS. RENAL COLIC. RETENTION OF URINE. STONE IN THE KIDNEY. SUPPRESSION OF URINE. URAEMIA. ... kidney disorders

Kidney

Either of the 2 organs that filter the blood and excrete waste products and excess water as urine. The kidneys are situated at the back of the abdominal cavity, on either side of the spine. Each kidney is surrounded by a fibrous capsule and is made up of an outer cortex and an inner medulla.

The cortex contains specialized capillaries called glomeruli, which, together with a series of tubules, make up the nephrons, the filtering units of the kidney. The nephrons filter blood under pressure and then selectively reabsorb water and certain other substances back into the blood. Urine is formed from substances that are not reabsorbed. The urine is conducted through tubules to the renal pelvis (the central collecting area of the kidney) and then through tubes called ureters to the bladder.

The kidneys also regulate the body’s fluid balance.

To do this, the kidneys excrete excess water, and when water is lost from the body (for example as a result of sweating), they conserve it (see ADH).

In addition, the kidneys control the body’s acid–base balance by adjusting urine acidity.

The kidneys are also involved in hormonal regulation of red blood cell production and blood pressure.... kidney

Artificial Kidney

See DIALYSIS.... artificial kidney

Kidney, Artificial

See DIALYSIS.... kidney, artificial

Kidneys

These are a pair of glands located in the upper abdomen close to the spine and embedded in fat and loose connective tissue.... kidneys

Kidneys, Diseases Of

Diseases affecting the kidneys can be broadly classi?ed into congenital and genetic disorders; autoimmune disorders; malfunctions caused by impaired blood supply; infections; metabolic disorders; and tumours of the kidney. Outside factors may cause functional disturbances – for example, obstruction in the urinary tract preventing normal urinary ?ow may result in hydronephrosis (see below), and the CRUSH SYNDROME, which releases proteins into the blood as a result of seriously damaged muscles (rhabdomyolosis), can result in impaired kidney function. Another outside factor, medicinal drugs, can also be hazardous to the kidney. Large quantities of ANALGESICS taken over a long time damage the kidneys and acute tubular NECROSIS can result from certain antibiotics.

K

Diagram of glomerulus (Malpighian corpuscle).

Fortunately the body has two kidneys and, as most people can survive on one, there is a good ‘functional reserve’ of kidney tissue.

Symptoms Many patients with kidney disorders do not have any symptoms, even when the condition is quite advanced. However,

others experience loin pain associated with obstruction (renal colic) or due to infection; fevers; swelling (oedema), usually of the legs but occasionally including the face and arms; blood in the urine (haematuria); and excess quantities of urine (polyuria), including at night (nocturia), due to failure of normal mechanisms in the kidney for concentrating urine. Patients with chronic renal failure often have very di?use symptoms including nausea and vomiting, tiredness due to ANAEMIA, shortness of breath, skin irritation, pins and needles (paraesthesia) due to damage of the peripheral nerves (peripheral neuropathy), and eventually (rarely seen nowadays) clouding of consciousness and death.

Signs of kidney disease include loin tenderness, enlarged kidneys, signs of ?uid retention, high blood pressure and, in patients with end-stage renal failure, pallor, pigmentation and a variety of neurological signs including absent re?exes, reduced sensation, and a coarse ?apping tremor (asterixis) due to severe disturbance of the body’s normal metabolism.

Renal failure Serious kidney disease may lead to impairment or failure of the kidney’s ability to ?lter waste products from the blood and excrete them in the urine – a process that controls the body’s water and salt balance and helps to maintain a stable blood pressure. Failure of this process causes URAEMIA – an increase in urea and other metabolic waste products – as well as other metabolic upsets in the blood and tissues, all of which produce varying symptoms. Failure can be sudden or develop more slowly (chronic). In the former, function usually returns to normal once the underlying cause has been treated. Chronic failure, however, usually irreparably reduces or stops normal function.

Acute failure commonly results from physiological shock following a bad injury or major illness. Serious bleeding or burns can reduce blood volume and pressure to the point where blood-supply to the kidney is greatly reduced. Acute myocardial infarction (see HEART, DISEASES OF) or pancreatitis (see PANCREAS, DISORDERS OF) may produce a similar result. A mismatched blood transfusion can produce acute failure. Obstruction to the urine-?ow by a stone (calculus) in the urinary tract, a bladder tumour or an enlarged prostate can also cause acute renal failure, as can glomerulonephritis (see below) and the haemolytic-uraemia syndrome.

HYPERTENSION, DIABETES MELLITUS, polycystic kidney disease (see below) or AMYLOIDOSIS are among conditions that cause chronic renal failure. Others include stone, tumour, prostatic enlargement and overuse of analgesic drugs. Chronic failure may eventually lead to end-stage renal failure, a life-threatening situation that will need DIALYSIS or a renal transplant (see TRANSPLANTATION).

Familial renal disorders include autosomal dominant inherited polycystic kidney disease and sex-linked familial nephropathy. Polycystic kidney disease is an important cause of renal failure in the UK. Patients, usually aged 30–50, present with HAEMATURIA, loin or abdominal discomfort or, rarely, urinary-tract infection, hypertension and enlarged kidneys. Diagnosis is based on ultrasound examination of the abdomen. Complications include renal failure, hepatic cysts and, rarely, SUBARACHNOID HAEMORRHAGE. No speci?c treatment is available. Familial nephropathy occurs more often in boys than in girls and commonly presents as Alport’s syndrome (familial nephritis with nerve DEAFNESS) with PROTEINURIA, haematuria, progressing to renal failure and deafness. The cause of the disease lies in an absence of a speci?c ANTIGEN in a part of the glomerulus. The treatment is conservative, with most patients eventually requiring dialysis or transplantation.

Acute glomerulonephritis is an immune-complex disorder due to entrapment within glomerular capillaries of ANTIGEN (usually derived from B haemolytic streptococci – see STREPTOCOCCUS) antibody complexes initiating an acute in?ammatory response (see IMMUNITY). The disease affects children and young adults, and classically presents with a sore throat followed two weeks later by a fall in urine output (oliguria), haematuria, hypertension and mildly abnormal renal function. The disease is self-limiting with 90 per cent of patients spontaneously recovering. Treatment consists of control of blood pressure, reduced ?uid and salt intake, and occasional DIURETICS and ANTIBIOTICS.

Chronic glomerulonephritis is also due to immunological renal problems and is also classi?ed by taking a renal biopsy. It may be subdivided into various histological varieties as determined by renal biospy. Proteinuria of various degrees is present in all these conditions but the clinical presentations vary, as do their treatments. Some resolve spontaneously; others are treated with steroids or even the cytotoxic drug CYCLOPHOSPHAMIDE or the immunosuppressant cyclosporin. Prognoses are generally satisfactory but some patients may require renal dialysis or kidney transplantation – an operation with a good success rate.

Hydronephrosis A chronic disease in which the kidney becomes greatly distended with ?uid. It is caused by obstruction to the ?ow of urine at the pelvi-ureteric junction (see KIDNEYS – Structure). If the ureter is obstructed, the ureter proximal to the obstruction will dilate and pressure will be transmitted back to the kidney to cause hydronephrosis. Obstruction may occur at the bladder neck or in the urethra itself. Enlargement of the prostate is a common cause of bladder-neck obstruction; this would give rise to hypertrophy of the bladder muscle and both dilatation of the ureter and hydronephrosis. If the obstruction is not relieved, progressive destruction of renal tissue will occur. As a result of the stagnation of the urine, infection is probable and CYSTITIS and PYELONEPHRITIS may occur.

Impaired blood supply may be the outcome of diabetes mellitus and physiological shock, which lowers the blood pressure, also affecting the blood supply. The result can be acute tubular necrosis. POLYARTERITIS NODOSA and SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) may damage the large blood vessels in the kidney. Treatment is of the underlying condition.

Infection of the kidney is called pyelonephritis, a key predisposing factor being obstruction of urine ?ow through the urinary tract. This causes stagnation and provides a fertile ground for bacterial growth. Acute pyelonephritis is more common in women, especially during pregnancy when bladder infection (CYSTITIS) spreads up the ureters to the kidney. Symptoms are fever, malaise and backache. Antibiotics and high ?uid intake are the most e?ective treatment. Chronic pyelonephritis may start in childhood as a result of congenital deformities that permit urine to ?ow up from the bladder to the kidney (re?ux). Persistent re?ux leads to recurrent infections causing permanent damage to the kidney. Specialist investigations are usually required as possible complications include hypertension and kidney failure.

Tumours of the kidney are fortunately rare. Non-malignant ones commonly do not cause symptoms, and even malignant tumours (renal cell carcinoma) may be asymptomatic for many years. As soon as symptoms appear – haematuria, back pain, nausea, malaise, sometimes secondary growths in the lungs, bones or liver, and weight loss – urgent treatment including surgery, radiotherapy and chemotherapy is necessary. This cancer occurs mostly in adults over 40 and has a hereditary element. The prognosis is not good unless diagnosed early. In young children a rare cancer called nephroblastoma (Wilm’s tumour) can occur; treatment is with surgery, radiotherapy and chemotherapy. It may grow to a substantial size before being diagnosed.

Cystinuria is an inherited metabolic defect in the renal tubular reabsorption of cystine, ornithine, lysine and arginine. Cystine precipitates in an alkaline urine to form cystine stones. Triple phosphate stones are associated with infection and may develop into a very large branching calculi (staghorn calculi). Stones present as renal or ureteric pain, or as an infection. Treatment has undergone considerable change with the introduction of MINIMALLY INVASIVE SURGERY (MIS) and the destruction of stone by sound waves (LITHOTRIPSY).... kidneys, diseases of

Polycystic Disease Of The Kidney

An inherited disease in which the KIDNEYS contain many cysts. These grow in size until normal kidney tissue is largely destroyed. Cysts may also occur in other organs such as the liver. In adults, the disease will cause HYPERTENSION and kidney failure. There is also a juvenile form. There is no e?ective treatment, although symptoms can be alleviated by DIALYSIS and sometimes kidney transplant (see TRANSPLANTATION).... polycystic disease of the kidney

Structure Each Kidney Is About 10 Cm Long,

6.5 cm wide, 5 cm thick, and weighs around 140 grams.

Adult kidneys have a smooth exterior, enveloped by a tough ?brous coat that is bound to the kidney only by loose ?brous tissue and by a few blood vessels that pass between it and the kidney. The outer margin of the kidney is convex; the inner is concave with a deep depression, known as the hilum, where the vessels enter. The URETER, which conveys URINE to the URINARY BLADDER, is also joined at this point. The ureter is spread out into an expanded, funnel-like end, known as the pelvis, which further divides up into little funnels known as the calyces. A vertical section through a kidney (see diagram) shows two distinct layers: an outer one, about 4 mm thick, known as the cortex; and an inner one, the medulla, lying closer to the hilum. The medulla consists of around a dozen pyramids arranged side by side, with their base on the cortex and their apex projecting into the calyces of the ureter. The apex of each pyramid is studded with tiny holes, which are the openings of the microscopic uriniferous tubes.

In e?ect, each pyramid, taken together with the portion of cortex lying along its base, is an independent mini-kidney. About 20 small tubes are on the surface of each pyramid; these, if traced up into its substance, repeatedly subdivide so as to form bundles of convoluted tubules, known as medullary rays, passing up towards the cortex. One of these may be traced further back, ending, after a tortuous course, in a small rounded body: the Malpighian corpuscle or glomerulus (see diagram). Each glomerulus and its convoluted tubule is known as a nephron, which constitutes the functional unit of the kidney. Each kidney contains around a million nephrons.

After entering the kidney, the renal artery divides into branches, forming arches where the cortex and medulla join. Small vessels come o? these arches and run up through the cortex, giving o? small branches in each direction. These end in a tuft of capillaries, enclosed in Bowman’s capsule, which forms the end of the uriniferous tubules just described; capillaries with capsule constitute a glomerulus.

After circulating in the glomerulus, the blood leaves by a small vein, which again divides into capillaries on the walls of the uriniferous tubules. From these it is ?nally collected into the renal veins and then leaves the kidney. This double circulation (?rst through the glomerulus and then around the tubule) allows a large volume of ?uid to be removed from the blood in the glomerulus, the concentrated blood passing on to the uriniferous tubule for removal of parts of its solid contents. Other arteries come straight from the arches and supply the medulla direct; the blood from these passes through another set of capillaries and ?nally into the renal veins. This circulation is con?ned purely to the kidney, although small connections by both arteries and veins exist which pass through the capsule and, joining the lumbar vessels, communicate directly with the aorta.

Function The kidneys work to separate ?uid and certain solids from the blood. The glomeruli ?lter from the blood the non-protein portion of the plasma – around 150–200 litres in 24 hours, 99 per cent of which is reabsorbed on passing through the convoluted tubules.

Three main groups of substances are classi?ed according to their extent of uptake by the tubules:

(1) SUBSTANCES ACTIVELY REABSORBED These include amino acids, glucose, sodium, potassium, calcium, magnesium and chlorine (for more information, see under separate entries).

(2) SUBSTANCES DIFFUSING THROUGH THE TUBULAR EPITHELIUM when their concentration in the ?ltrate exceeds that in the PLASMA, such as UREA, URIC ACID and phosphates.

(3) SUBSTANCES NOT RETURNED TO THE BLOOD from the tubular ?uid, such as CREATINE, accumulate in kidney failure, resulting in general ‘poisoning’ known as URAEMIA.... structure each kidney is about 10 cm long,

Artificial Kidney

The common name for the machine used in dialysis.... artificial kidney

Kidney Biopsy

A procedure in which a small sample of kidney tissue is removed and examined under a microscope.

Kidney biopsy is performed to investigate and diagnose serious kidney disorders, such as glomerulonephritis, proteinuria, nephrotic syndrome, and acute kidney failure, or to assess the kidneys’ response to treatment.

There are 2 basic techniques: percutaneous needle biopsy, in which a hollow needle is passed through the skin into the kidney under local anaesthesia; and open surgery under general anaesthesia.... kidney biopsy

Kidney Cyst

A fluid-filled sac in the kidney. Most kidney cysts are noncancerous. Cysts commonly develop in people over 50 and may occur singly or multiply in 1 or both kidneys. Most cysts occur for no known reason and do not usually produce symptoms unless they become large enough to cause pain in the lower back due to pressure. However, large numbers of cysts in the kidneys may be associated with polycystic kidney disease (see kidney, polycystic), which often leads to kidney failure. Treatment of simple cysts is not usually necessary, but aspiration (withdrawal of fluid) or surgical removal may be carried out if a cyst is painful or recurs.... kidney cyst

Tea For Kidney Problems

If you’re experiencing abdominal pain and you’re sure it’s not a digestive tract ailment, it’s very possible that you’re suffering from a kidney disorder. The same if the pain is localized in the back or on one side of your body. Usually, kidney problems appear when there’s something wrong with your urinary tract and not only. Overexposing your body to low temperatures may cause urinary infections, impurity accumulations lead to kidney stones. Also, kidney problems can be caused by other health complaints, such as pulmonary edema and cancers. However, it’s best to schedule an appointment with your doctor in order to find out what’s actually going on with your body. How a Tea for Kidney Problems Works A Tea for Kidney Problems’ main goal is to purify your body by triggering a positive response from it. Once the main substances of these teas reach the affected areas, your organism produces enough endorphins (which are cells specialized in making you feel a lot better by bringing relief to your wounds) and antibodies to reconstruct the damaged tissue. Efficient Tea for Kidney Problems In order to work properly, a Tea for Kidney Problems needs to be both efficient and one hundred percent safe. Also, it must contain the right amount of nutrients, natural enzymes, volatile oils, antioxidants and minerals (sodium, magnesium, iron and manganese). This way, that tea will make your body eliminate the unwanted impurities and improve your kidney function. If you don’t know which teas would be appropriate for your condition, here’s a list to choose from: - Dandelion Tea – can be prepared from dandelion roots and it’s also a great adjuvant in diarrhea and urinary infection cases. This Tea for Kidney Problems has a bitter taste, but you can add ginger, lemon, mint or honey in order to make it more adequate for you. Avoid it at all costs if you’re pregnant or breastfeeding: due to its strong purgative and diuretic properties, Dandelion Tea can cause uterine contractions which may lead to miscarriages. - Marshmallow Root Tea – this lovely tea with a hint of Christmas is useful for a large variety of problems, from infertility to gastrointestinal and digestive complaints. Take a sip at every 5 minutes for an hour and enjoy the wonderful health benefits! - Buchu Tea – contains antioxidants and antibacterial agents, being a great help in cases of cystitis, urethritis and kidney failure. This Tea for Kidney acts like a natural diuretic and should not be taken by pregnant women. - Green Tea – as the scientists have proved, this decoction contains all the ingredients necessary to sustain life, so it’s useful for many problems, not just kidney disorders. However, don’t take it if you’re experiencing menstrual and menopausal symptoms (it can cause uterine contractions and stomach acidity). Tea for Kidney Problems Side Effects When taken properly, these teas are generally safe. However, exceeding the number of cups recommended per day might lead to a number of health problems such as miscarriages, hallucinations, headaches and skin rash. If you’ve been taking one of these teas and something doesn’t feel quite right, talk to your doctor as soon as possible. Don’t take a Tea for Kidney Problems if you’re pregnant, breastfeeding, on blood thinners or anticoagulants. The same advice if you’re preparing for a surgery. If you have the medical approval and there’s nothing that could interfere with your treatment, choose a Tea for Kidney problems that fits best your needs and give it a try today!  ... tea for kidney problems

Cancer – Kidney

Cancer of the kidney may appear in the renal pelvis, the area where urine is collected, or as a hypernephroma in the kidney itself. Not common. Symptoms include blood in the urine but with little pain. Herbal anti-neoplastics may enable the body to tolerate and reduce the toxicity of chemotherapy, the following being subordinate to conventional treatment.

Formula. Corn Silk 3; Plantain (Plantago major L) 2; Golden Rod 1; Hydrangea 1; Valerian half. Dosage: thrice daily before meals. Liquid Extracts: 1 teaspoon. Tinctures: 2 teaspoons. Powders: two 00 capsules or one-third teaspoon. This may be used as a basic combination to be adapted to a changing clinical picture.

Treatment by a general medical practitioner or oncologist. ... cancer – kidney

Kidney Function Tests

Tests performed to investigate kidney disorders.

Urinalysis is a simple test in which a urine sample is examined under a microscope for blood cells, pus cells, and casts (cells and mucous material that accumulate in the tubules of the kidneys and pass into the urine).

Urine may be tested for substances, such as proteins, that leak into the urine when the kidneys are damaged.

Kidney function can be assessed by measuring the concentration in the blood of substances, such as urea and creatinine, that the kidneys normally excrete.

Kidney function may also be assessed by kidney imaging techniques.... kidney function tests

Polycystic Kidney

See kidney, polycystic.... polycystic kidney

Acute Kidney Injury

see AKI.... acute kidney injury

Dysplastic Kidneys

any developmental abnormalities resulting from anomalous metanephric differentiation (see metanephros). Most dysplastic kidneys are associated either with an abnormally located ureteral orifice or with urinary tract anomalies that are expected to produce unilateral, bilateral, or segmental urinary obstruction.... dysplastic kidneys

Kidney Cancer

A cancerous tumour of the kidney. Most kidney cancers originate in the kidney itself, but in rare cases cancer spreads to the kidney from another organ. There are 3 main types of kidney cancer. The most common, renal cell carcinoma, usually occurs in people over 40. Nephroblastoma (also called Wilms’ tumour) is a fast-growing tumour that mainly affects children under 5. Transitional cell carcinoma arises from cells lining the renal pelvis; it is more common in smokers or those who have taken analgesic drugs for a long time.Symptoms of kidney cancer vary. It is often symptomless in the early stages, although later there may be blood in the urine. All types require surgical removal of the kidney and sometimes also of the ureter. For nephroblastoma, surgery is followed by treatment with anticancer drugs. Kidney cancer is likely to be fatal if it has spread to other organs before treatment is started.... kidney cancer

Kidney Imaging

Techniques for visualizing the kidneys, usually performed for diagnosis. Ultrasound scanning can be used to identify kidney enlargement, a cyst or tumour, and the site of any blockage. Conventional X-rays show the outline of the kidneys and most kidney stones. Intravenous urography shows the internal anatomy of the kidney and ureters. Angiography is used to image blood circulation through the kidneys. CT scanning and MRI provide detailed cross-sectional images and can show abscesses or tumours. Two types of radionuclide scanning are used for the kidney: DMSA and DTPA scanning. DMSA is a substance given by intravenous injection that binds to cells in the kidney tubule, giving a single, static picture of the kidneys. DTPA, also given intravenously, is filtered in the kidneys and passes out in the urine. Pictures taken at intervals record its passage through the urinary tract and show kidney function. ... kidney imaging

Kidney, Polycystic

An inherited disorder in which both kidneys are affected by numerous cysts that gradually enlarge until most of the normal kidney tissue is destroyed.

Polycystic kidney disease is distinguished from multiple simple kidney cysts, which occur commonly with age.

There are 2 types of polycystic disease.

The most common usually becomes apparent in middle age, producing abdominal swelling, pain, and blood in the urine.

As the disease progresses, hypertension and kidney failure may result.

The rare type causes enlargement of the kidneys and kidney failure in infants and young children.

There is no effective treatment for preserving kidney function in either type, but symptoms of kidney failure can be treated by dialysis and kidney transplant.... kidney, polycystic

Myeloma Kidney

see cast nephropathy.... myeloma kidney

Polycystic Disease Of The Kidneys

either of two inherited disorders in which renal cysts are a common feature. Autosomal recessive polycystic kidney disease (ARPKD) occurs in about 1 in 20,000 live births. It is due to a single mutation on chromosome 6 for the gene encoding the protein fibrocystin. The majority of cases are diagnosed before or at birth. The most severely affected fetuses have enlarged kidneys and *oligohydramnios due to poor fetal renal output. These fetuses develop the ‘Potter’ phenotype with characteristic facies, pulmonary hypoplasia, and deformities of the spine and limbs. Those surviving the neonatal period (50–70%) develop varying degrees of renal impairment but this may not proceed to end-stage until early adulthood.

Autosomal dominant polycystic kidney disease (ADPKD) affects between 1 in 400 and 1 in 1000 individuals and is one of the most common hereditary diseases. Two types have been defined. ADPKD 1 is the commonest and responsible for about 85% of cases. It is due to a mutation in the PKD1 gene on chromosome 16, which encodes polycystin 1, an *ion-channel-regulating protein. ADPKD2 is due to a mutation in the PKD2 gene on chromosome 4, which encodes the protein polycystin 2, a calcium-release channel. ADPKD2 tends to be a milder disease with later presentation.

ADPKD is a multisystem disorder that is also associated with cyst formation in other organs (particularly the liver), cardiovascular disorders, and colonic diverticular disease. Renal disease presents in early adult life with haematuria, loin pain, urinary tract infection, hypertension, renal stone disease, or the finding of a mass in the abdomen. Other cases are identified by family contact tracing; the findings of a few cysts on renal ultrasonography in a young adult with a family history of ADPKD is highly suggestive of the disease. Renal disease is progressive and about 50% of patients will have reached end-stage by the time they enter their seventh decade. The progress of the renal failure can be slowed by good blood pressure control. In the UK, patients with ADPKD are responsible for 5–10% of the total on renal replacement therapy.

There are a number of separate rare autosomal dominant conditions other than ADPKD1 and ADPKD 2 that can present with polycystic kidneys. These include *von Hippel-Lindau disease and *tuberous sclerosis.... polycystic disease of the kidneys




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