Various gases, liquids and solids will emit light when they are suitably stimulated. A gassed laser is pumped by the ionising e?ect of a high-voltage current. This is the same process as that used in a ?uorescent tube. Each type of laser has a di?erent e?ect on biological tissues and this is related to the wavelength of the light produced. The wavelength determines the degree of energy absorption by di?erent tissues, and because of this, di?erent lasers are needed for di?erent tasks. The argon laser produces light in the visible green wavelength which is selectively absorbed by HAEMOGLOBIN. It heats and coagulates (see COAGULATION) tissues so can be used to seal bleeding blood vessels and to selectively destroy pigmented lesions. The carbon-dioxide laser is the standard laser for cutting tissue: the infra-red beam it produces is strongly absorbed by water and so vaporises cells. Thus, by moving a ?nely focused beam across the tissue, it is possible to make an incision.
The two main uses of laser in surgery are the endoscopic (see ENDOSCOPE) photocoagulation of bleeding vessels, and the incision of tissue. Lasers have important applications in OPHTHALMOLOGY in the treatment of such disorders as detachment of the retina and the diabetic complications of proliferative retinopathy and of the cornea (see EYE, DISORDERS OF). The destruction of abnormal cells – a sign of pre-malignancy – in the CERVIX UTERI is done using lasers. The beams may also be used to remove scar tissue from the FALLOPIAN TUBES resulting from infection, thus unblocking the tubes and improving the chances of CONCEPTION. Lasers also have several important applications in DERMATOLOGY. They are used in the treatment of pigmented lesions such as LENTIGO, in the obliteration of port-wine stains, in the removal of small, benign tumours such as verrucas, and ?nally in the removal of tattoos.
Low-intensity laser beams promote tissue healing and reduce in?ammation, pain and swelling. Their e?ect is achieved by stimulating blood and lymph ?ow and by cutting the production of PROSTAGLANDINS, which provoke in?ammation and pain. The beams are used to treat ligament sprains, muscle tears and in?amed joints and tendons.
The three great advantages of lasers are their potency, their speed of action, and the ability to focus on an extremely small area. For these reasons they are widely used, and have allowed great advances to be made in microsurgery, and particularly in FIBREOPTIC ENDOSCOPY.... laser
They work by blocking the reabsorption of the neurotransmitter serotonin following its release in the brain.
The increased serotonin levels that result are associated with improved mood.
Common drugs in this group include fluoxetine and sertraline.
SSRIs are usually taken orally once a day; it may take 1–3 weeks for any noticeable improvement in symptoms.
SSRIs usually produce fewer side effects than other types of antidepressant drug.
However, they may cause diarrhoea, nausea, restlessness, and anxiety.... selective serotonin reuptake inhibitors