Respiratory syncytial virus Health Dictionary

Respiratory Syncytial Virus: From 1 Different Sources


(RSV) a paramyxovirus (see myxovirus) that causes infections of the nose and throat. It is a major cause of bronchiolitis and pneumonia in young children. In tissue cultures infected with the virus, cells merge together to form a conglomerate (syncytium). RSV is thought to have a role in *sudden infant death syndrome. Vulnerable children can be treated with *ribavirin, but most children just require supportive measures.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Respiratory Arrest

Cessation of breathing, often caused by envenomation (or poisoning).... respiratory arrest

Respiratory System

All the organs and tissues associated with the act of RESPIRATION or breathing. The term includes the nasal cavity (see NOSE) and PHARYNX, along with the LARYNX, TRACHEA, bronchi (see BRONCHUS), BRONCHIOLES and LUNGS. The DIAPHRAGM and other muscles, such as those between the RIBS, are also part of the respiratory system which is responsible for oxygenating the blood and removing carbon dioxide from it.... respiratory system

Epstein Barr Virus

The virus that causes glandular fever or infectious MONONUCLEOSIS. It is similar to the viruses that cause herpes and is associated with BURKITT’S LYMPHOMA. It has been suggested as precipitating some attacks of MYALGIC ENCEPHALOMYELITIS (ME), also known as CHRONIC FATIGUE SYNDROME (CFS).... epstein barr virus

Virus

An extremely small infective agent requiring living cells for replication. Are either RNA or DNA, never both.... virus

Respiratory Distress Syndrome

This may occur in adults as ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS), or in newborn children, when it is also known as HYALINE MEMBRANE DISEASE. The adult syndrome consists of PULMONARY OEDEMA of non-cardiac origin. The process begins when tissue damage stimulates the autonomic nervous system, releases vasoactive substances, precipitates complement activation, and produces abnormalities of the clotting cascade – the serial process that leads to clotting of the blood (see COAGULATION). The activation of complement causes white cells to lodge in the pulmonary capillaries where they release substances which damage the pulmonary endothelium.

Respiratory distress syndrome is a complication of SHOCK, systemic SEPSIS and viral respiratory infections. It was ?rst described in 1967, and – despite advances with assisted ventilation

– remains a serious disease with a mortality of more than 50 per cent. The maintenance of adequate circulating blood volume, peripheral PERFUSION, acid-base balance and arterial oxygenation is important, and assisted ventilation should be instituted early.

In newborns the mechanism is diferent, being provoked by an inability of the lungs to manufacture SURFACTANT.... respiratory distress syndrome

Slow Virus

See prion.... slow virus

West Nile Virus

A mosquito-borne viral infection that is normally harmless to healthy people who, if infected, develop a mild ?u-like illness. However, if the elderly and those in poor health, particularly immunocompromised patients, are infected, they may develop fatal in?ammation of the brain and spinal cord. In Israel in 2000, 12 people died and more than 155 survived an outbreak; and in New York in 1999, more than 60 people were infected, of whom six died. The disease was ?rst reported in Uganda in 1937 and became ENDEMIC in the Middle East and Africa, recently spreading to Europe, central Asia, Oceania and America. Mosquitoes bearing the ?aviviridae-family virus usually contract it by biting infected poultry, but the infection has been found in mammals, such as cats, dogs and horses.... west nile virus

Acute Respiratory Distress Syndrome (ards)

Formerly known as adult respiratory distress syndrome. A form of acute respiratory failure in which a variety of di?erent disorders give rise to lung injury by what is thought to be a common pathway. The condition has a high mortality rate (about 70 per cent); it is a complex clinical problem in which a disproportionate immunological response plays a major role. (See IMMUNITY.)

The exact trigger is unknown, but it is thought that, whatever the stimulus, chemical mediators produced by cells of the immune system or elsewhere in the body spread and sustain an in?ammatory reaction. Cascade mechanisms with multiple interactions are provoked. CYTOTOXIC substances (which damage or kill cells) such as oxygen-free radicals and PROTEASE damage the alveolar capillary membranes (see ALVEOLUS). Once this happens, protein-rich ?uid leaks into the alveoli and interstitial spaces. SURFACTANT is also lost. This impairs the exchange of oxygen and carbon dioxide in the lungs and gives rise to the clinical and pathological picture of acute respiratory failure.

The typical patient with ARDS has rapidly worsening hypoxaemia (lack of oxygen in the blood), often requiring mechanical ventilation. There are all the signs of respiratory failure (see TACHYPNOEA; TACHYCARDIA; CYANOSIS), although the chest may be clear apart from a few crackles. Radiographs show bilateral, patchy, peripheral shadowing. Blood gases will show a low PaO2 (concentration of oxygen in arterial blood) and usually a high PaCO2 (concentration of carbon dioxide in arterial blood). The lungs are ‘sti?’ – they are less e?ective because of the loss of surfactant and the PULMONARY OEDEMA.

Causes The causes of ARDS may be broadly divided into the following:... acute respiratory distress syndrome (ards)

Barmah Forest Virus

A mosquito-borne arbovirus causing symptoms similar to Ross River virus infection in Australia. (See also Ross River virus).... barmah forest virus

Coxsackie Viruses

A group of viruses so-called because they were ?rst isolated from two patients with a disease resembling paralytic POLIOMYELITIS, in the village of Coxsackie in New York State. Thirty distinct types have now been identi?ed. They constitute one of the three groups of viruses included in the family of ENTEROVIRUSES, and are divided into two groups: A and B. Despite the large number of types of group A virus (24) in existence, evidence of their role in causing human disease is limited. Some, however, cause aseptic MENINGITIS, non-specicifc upper respiratory infection and MYOCARDITIS, and others cause a condition known as HERPANGINA. HAND, FOOT AND MOUTH DISEASE is another disease caused by the A group. All six types of group B virus have been associated with outbreaks of aseptic meningitis, and they are also the cause of BORNHOLM DISEASE. Epidemics of type B2 infections tend to occur in alternate years. (See VIRUS.)... coxsackie viruses

Ebola Virus Disease

Ebola virus disease is another name for VIRAL HAEMORRHAGIC FEVER. The ebola virus is one of the most virulent micro-organisms known. Like the marburg virus (see MARBURG DISEASE), it belongs to the ?lovirus group which originates in Africa. Increased population mobility and wars have meant that the infection occasionally occurs elsewhere, with air travellers developing symptoms on returning home.

Treatment As the disease can be neither prevented nor cured, treatment is supportive, with strict anti-infection procedures essential as human-to-human transmission can occur via skin and mucous-membrane contacts. Incubation period is 5–10 days. Fever with MYALGIA and headache occur initially, often accompanied by abdominal and chest symptoms. Haemorrhagic symptoms soon develop and the victim either starts to improve in the second week or develops multi-organ failure and lapses into a coma. Mortality ranges from 25 to 90 per cent.... ebola virus disease

Hendra Virus

Virus of Flying Foxes (Fruit Bats) in Australia. Can infect horses and humans. Also known as the Equine morbillivirus.... hendra virus

Hepatitis Viruses

The most common causes of viral hepatitis are those caused by the Hepatitis A, B, C, D, E and G viruses. Hepatitis F virus has been described but is a doubtful entity. Other viruses which can cause hepatitis include the Epstein-Barr Virus, cytomegalovirus, and the Yellow Fever virus.... hepatitis viruses

Herpes Simplex Virus

Causative virus of genital herpes and herpes labalis or cold sores.... herpes simplex virus

Herpes Viruses

One member of a group of viruses containing DNA which cause latent infections in animals and humans. Viruses from this group cause HERPES SIMPLEX, HERPES ZOSTER (shingles) and CHICKENPOX, and include CYTOMEGALOVIRUS (CCMV) and EPSTEIN-BARR VIRUS.... herpes viruses

Herpes Zoster Virus

Causative virus of chicken pox and shingles.... herpes zoster virus

Hiv (human Immunodeficiency Virus)

The name of the causative agent of AIDS.... hiv (human immunodeficiency virus)

Human Immunodeficiency Virus

See AIDS/HIV.... human immunodeficiency virus

Lyssa Virus

A group of rhabdoviruses closely related to the rabies virus. The Australian Bat Lyssa virus is found in flying foxes (fruit bats) and can cause a rabies-like disease in humans. The disease should be handled as for rabies and can be prevented by using rabies vaccine.... lyssa virus

Monkey B Virus

A herpes virus of monkeys that can infect humans, usually through handling monkey tissues at autopsy or in the laboratory.... monkey b virus

Nipah Virus

Virus first identified from the village of Nipah in Malaysia. Carried by flying foxes (fruit bats). Can infect pigs and humans.... nipah virus

Papova Viruses

These include the human papilloma viruses (HPV), of which nearly a hundred strains have been identi?ed. HPV cause verrucae (see WARTS) on skin and, less often, on the mucous membranes of mouth, larynx, genitalia and the cervix. Some strains may predispose to eventual cancer.... papova viruses

Parainfluenza Viruses

These are included in the paramyxoviruses (see MYXOVIRUSES) and divided into four types, all of which cause infection of the respiratory system (see RESPIRATION). Infection with type 3 begins in May, reaches a maximum in July or August and returns to base-line level in October. Types 1 and 2 are predominantly winter viruses. Children are commonly affected and the manifestations include CROUP, fever, and a rash.... parainfluenza viruses

Picorna Viruses

These infectious agents derive their name from pico (small) and from RNA (because they contain ribonuleic acid). They are a group of viruses which includes the ENTEROVIRUSES and the RHINOVIRUSES.... picorna viruses

Respiratory Syncytial Virus (rsv)

Usually known as RSV, this is one of the MYXOVIRUSES. It is among the major causes of BRONCHIOLITIS and PNEUMONIA among infants aged under 6 months; its incidence has been increasing, possibly due to atmospheric pollution.... respiratory syncytial virus (rsv)

Respiratory Therapy

The diagnostic evaluation, management and treatment of the care of older persons with deficiencies and abnormalities of the cardiopulmonary (heart lung) system.... respiratory therapy

Ross River Virus

A mosquito-borne arbovirus causing epidemic polyarthritis in Australia and certain islands of the Western Pacific to which it has spread.... ross river virus

Severe Acute Respiratory Syndrome (sars)

See SARS.... severe acute respiratory syndrome (sars)

Epstein–barr Virus

A virus that causes infectious mononucleosis; the virus is also associated with Burkitt’s lymphoma and cancer of the nasopharynx (see nasopharynx, cancer of).... epstein–barr virus

Respiratory Failure

A condition in which there is a buildup of carbon dioxide and a fall in the level of oxygen in the blood (see hypoxia). Causes include lung disorders, such as severe asthma, emphysema, or chronic bronchitis (see pulmonary disease, chronic obstructive), or damage to the respiratory centre in the brain due to, for example, an overdose of opioid drugs, a stroke, or serious head injury.

Treatment is with ventilation and oxygen for the underlying cause.... respiratory failure

Respiratory Function Tests

See pulmonary function tests.... respiratory function tests

Respiratory Tract Infection

Infection of the breathing passages, which extend from the nose to the alveoli. This type of infection is divided into upper and lower respiratory tract infections. Upper respiratory tract infections affect the nose, throat, sinuses, and larynx. They include the common cold, pharyngitis, tonsillitis, sinusitis, laryngitis, and croup. Lower respiratory tract infections, which affect the trachea, bronchi, and lungs, include acute bronchitis, acute bronchiolitis, and pneumonia.... respiratory tract infection

Slow Virus Diseases

A group of diseases of the central nervous system that occur many months or even years after infection with a virus. They cause gradual widespread destruction of nerve tissue, with progressive loss of brain function and a fatal outcome. Examples include Creutzfeldt–Jakob disease and kuru.... slow virus diseases

Hantaan Virus

Haemorrhagic fever with kidney syndrome (HFRS). Has been known for years by the Chinese and other nations of antiquity. Over 3,000 cases recorded during the Korean War (1951- 1952), the disease taking its name from the River Hantaan, South Korea.

Cause: a virus spread by field mice, rats and other rodents. Incubation period: 2-3 weeks.

Symptoms: fever, headache, backache, severe nervous prostration, low blood pressure, red patches on skin, failure of kidneys, high protein levels in urine. Small red or purple spots indicate bleeding beneath the skin.

Treatment. Traditional. Ayurvedic:– Gotu Kola, Juniper. Dr Mattiolus regards Juniper as a preventative of the pestilence.

To be treated by or in liaison with a qualified medical practitioner. HARPAGOPHYTUM. See: DEVIL’S CLAW. ... hantaan virus

Viruses

The smallest known types of infectious agent. It is debatable whether viruses are truly living organisms or just collections of molecules capable of selfreplication under specific conditions. Their sole activity is to invade the cells of other organisms, which they then take over to make copies of themselves. Outside living cells, viruses are inert.

A single virus particle (virion) consists of an inner core of nucleic acid, which may be either DNA or RNA, surrounded

by 1 or 2 protective protein shells (capsids). Surrounding the outer capsid may be another layer, the viral envelope, which consists mainly of protein. The nucleic acid consists of a string of genes that contain coded instructions for making copies of the virus.

Common viral diseases include the common cold, influenza, and chickenpox (caused by the varicella–zoster virus). AIDS is caused by the human immunodeficiency virus (HIV).... viruses

Acute Respiratory Distress Syndrome

see adult respiratory distress syndrome.... acute respiratory distress syndrome

Acute Respiratory Failure

(ARF) a primary disorder of gaseous exchange (as distinct from failure of the mechanical process of breathing). The prototype of ARF is *adult respiratory distress syndrome, but the term sometimes also refers to disruption of any other part of the respiratory system, including the respiratory control centre in the brain with its *efferent and *afferent pathways.... acute respiratory failure

Adult Respiratory Distress Syndrome

(acute respiratory distress syndrome, ARDS) a form of *acute respiratory failure that occurs after a precipitating event, such as trauma, aspiration, or inhalation of a toxic substance; it is particularly associated with septic shock. Lung injury is characterized by reduced oxygen in the arteries, reduced lung volume, and decreased lung compliance, and diffuse infiltrates are seen on a chest X-ray. Treatment is correction of the original cause, volume replacement, diuretics, oxygen, and mechanical ventilation.... adult respiratory distress syndrome

Coxsackie Virus

(echovirus) one of a group of RNA-containing viruses that are able to multiply in the gastrointestinal tract (see enterovirus). About 30 different types exist. Type A Coxsackie viruses generally cause less severe and less well-defined diseases, such as *hand, foot, and mouth disease, although some cause meningitis and severe throat infections (see herpangina). Type B Coxsackie viruses cause inflammation or degeneration of heart tissue, resulting in pericarditis or myocarditis, or brain tissue, producing meningitis or encephalitis. They can also attack the muscles of the chest wall, the bronchi, pancreas, thyroid, or conjunctiva and recent evidence suggests they may be implicated in diabetes in children and in motor neuron disease. See also Bornholm disease.... coxsackie virus

Human Immunodeficiency Virus

see HIV.... human immunodeficiency virus

Middle East Respiratory Syndrome

(MERS) a viral respiratory infection that was first identified in 2012. Humans seem to be infected most easily by contact with dromedary camels (hence the informal name camel flu), although human-to-human infection also occurs. Symptoms include fever, cough, and shortness of breath. Although the syndrome is often mild, death occurs in about a third of diagnosed cases. Most reported cases have been in the Arabian Peninsula, although there was a major outbreak in South Korea in 2015. At present there is no vaccine or treatment.... middle east respiratory syndrome

Parainfluenza Viruses

a group of large RNA-containing viruses that cause infections of the respiratory tract producing mild influenza-like symptoms. They are included in the paramyxovirus group (see myxovirus).... parainfluenza viruses

Respiratory Quotient

(RQ) the ratio of the volume of carbon dioxide transferred from the blood into the alveoli to the volume of oxygen absorbed into the alveoli. The RQ is usually about 0.8 because more oxygen is taken up than carbon dioxide excreted.... respiratory quotient

Respiratory Rate

(RR) breathing rate: the number of breaths per minute. Normally between 6 and 12, it increases after exercise and in cases of *respiratory distress and decreases after head injury and opioid overdosage.... respiratory rate

Ebola Virus

a virus responsible for an acute infection in humans with features similar to those of *Marburg disease. Transmission is by contact with infected blood and other body fluids and the incubation period is 2–21 days (7 days on average). The mortality rate is 53–88%, but intensive treatment (including rehydration) in the early stages of the disease can halt its rapid and usually irreversible progression to haemorrhaging of internal organs. Until recently, sporadic but short-lived outbreaks have occurred in Africa since 1976, when the virus was first identified during an outbreak in the region of the Ebola river, in Zaïre (now Democratic Republic of Congo). A major epidemic of the disease broke out in West Africa at the end of 2013 and lasted until May 2016: over 11,000 people died. An unknown species of animal – possibly a fruit bat – is assumed to act as a reservoir for the virus between outbreaks of the disease in humans.... ebola virus

Respiratory Distress

severe difficulty in achieving adequate oxygenation in spite of significant efforts to breathe: it is usually associated with increased *respiratory rate and the use of *accessory muscles in the chest wall. It can occur in both obstructive and nonobstructive lung conditions. See adult respiratory distress syndrome; airway obstruction; dyspnoea; respiratory distress syndrome; stridor.

respiratory distress syndrome (RDS; hyaline membrane disease) the condition of a newborn infant in which the lungs are imperfectly expanded. Initial inflation and normal expansion of the lungs requires the presence of a substance (*surfactant) that reduces the surface tension of the air sacs (alveoli) and prevents collapse of the small airways. Without surfactant the airways collapse, leading to inefficient and ‘stiff’ lungs. The condition is most common and serious among preterm infants, in whom surfactant may be deficient. It lasts 5–10 days, with worsening on days 2–3. Breathing is rapid, laboured, and shallow, and microscopic examinations of lung tissue in fatal cases has revealed the presence of *hyalin material in the collapsed air sacs. The condition is treated by careful nursing, intravenous fluids, and oxygen, with or without positive-pressure ventilation (see noninvasive ventilation). Early surfactant replacement therapy has been shown to reduce the severity of RDS and when given prophylactically it has been demonstrated to improve clinical outcome. See also adult respiratory distress syndrome.... respiratory distress

Zika Virus

a mosquito-borne virus that usually causes mild symptoms in humans, including fever, skin rashes, muscle and joint pain, and headache. However, infection during pregnancy can result in brain abnormalities of the fetus, notably *microcephaly. Zika virus can also trigger *Guillain–Barré syndrome. Infection is usually from a mosquito bite, although the virus may also be transmitted by sexual intercourse.... zika virus



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