Loprazolam Health Dictionary

Loprazolam: From 1 Different Sources


n. a short-acting benzodiazepine drug administered for the short-term treatment of insomnia (see hypnotic). Possible side-effects include drowsiness and confusion.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Benzodiazepines

A large family of drugs used as HYPNOTICS, ANXIOLYTICS, TRANQUILLISERS, ANTICONVULSANTS, premedicants, and for intravenous sedation. Short-acting varieties are used as hypnotics; longer-acting ones as hypnotics and tranquillisers. Those with high lipid solubility act rapidly if given intravenously.

Benzodiazepines act at a speci?c centralnervous-system receptor or by potentiating the action of inhibitory neuro-transmitters. They have advantages over other sedatives by having some selectivity for anxiety rather than general sedation. They are safer in overdose. Unfortunately they may cause aggression, amnesia, excessive sedation, or confusion in the elderly. Those with long half-lives or with metabolites having long half-lives may produce a hangover e?ect, and DEPENDENCE on these is now well recognised, so they should not be prescribed for more than a few weeks. Commonly used benzodiazepines include nitrazepam, ?unitrazepam (a controlled drug), loprazolam, temazepam (a controlled drug) and chlormethiazole, normally con?ned to the elderly. All benzodiazepines should be used sparingly because of the risk of dependence.... benzodiazepines

Hypnotic

(soporific) n. a drug that produces sleep by depressing brain function. Hypnotics include benzodiazepines (such as *loprazolam, *nitrazepam, and *temazepam) and drugs that act at benzodiazepine receptor sites, such as zaleplon, zolpidem, and zopiclone. Hypnotics are used for the short-term treatment of insomnia and sleep disturbances. Some of them (e.g. nitrazepam, *flurazepam) may cause hangover effects in the morning.... hypnotic



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