A general term for fats and oils. Lipids include triglycerides (simple fats), phospholipids (important constituents of cell membranes and nerve tissue), and sterols, such as cholesterol.
Cholesterol is necessary for maintenance of brain and glandular system, the production of bile salts and certain hormones.
Excesses plug arteries with a gluey consistency. Fats may start furring up arteries from childhood, yet it may take many years for symptoms to develop. The more meat and dairy products eaten the more cholesterol is produced. 90 per cent cases of gall stones are composed of cholesterol. A link between coronary heart disease and high cholesterol levels is strong and consistent. Anger and hostility raise cholesterol level.
The first indication of narrowing of the arteries may be an attack of angina, severe chest pain occurring on exertion due to an inadequate supply of blood and oxygen to the heart muscle. No one should exceed a fat and cholesterol count of 40 per day. For those of moderate risk level, a count of below 30 is advised.
Dr Paul Durrington, consultant physician, Manchester Royal Infirmary and researcher in lipids, believes that ‘reducing the amount of saturated fats in the diet and reducing weight are the most effective ways of lowering cholesterol levels’.
Treatment: same as for HYPERLIPIDAEMIA.
Diet. See: DIET – CHOLESTEROL. ... cholesterol
Habitat: Native to Central Asia. Cultivated all over India.
English: Garlic.Ayurvedic: Lashuna, Rasona, Yavaneshta, Ugragandha, Ma- haushadh, Arishta.Unani: Seer, Lahsun.Siddha/Tamil: Ullippoondu, Vellaip- pondu.Action: Antibiotic, bacteriostatic, fungicide, anthelmintic, antithrom- bic, hypotensive, hypoglycaemic, hypocholesterolaemic. Also used for upper respiratory tract infections and catarrhal conditions.
Key application: As a supportive to dietary measures for elevated levels of lipids in blood; as a preventive measure for age-dependent vascular changes. (German Commission E, ESCOP, WHO, The British Herbal Pharmacopoeia.) Also as an antimicrobial. (The British Herbal Pharmacopoeia). Garlic has been shown to be effective in respiratory infections and catarrhal conditions. (The British Herbal Compendium.)The Ayurvedic Pharmacopoeia ofIn- dia indicates the use of the bulb as a brain tonic in epilepsy and psychic disorders.Heavy consumption of garlic prior to surgery led to increased clotting time or reduced platelet aggregation (in human case reports). Garlic tablets at a dose of 400 mg twice daily for 12 weeks reduced platelet aggregation 59% compared with placebo in 80 patients (in human clinical study). (Francis Brinker.)Garlic cloves are high in sulphur- containing amino acids known as al- liin (no taste, no smell, no medicinal action). With crushing or chewing alli- in comes into contact with the enzyme alliinase. Alliinase, in less than 6 s, transforms alliin into allicin (strongly medicinal), which breaks down into a number of sulphur compounds including ajoene, vinyldithin and diallyl disulfide, and trisulfide. The antibiotic effect is attributed to allicin; hypogly- caemic effect to allicin and allylpro- phyldisulphide (also to S-allyl cysteine sulfoxide); anticarcinogenic activity to diallyl monosulfide; platelet aggregation inhibitory effect to diallyl-di- and tri-sulphides. Ajoene inactivated human gastric lipase, which is involved in digestion and absorption of dietary fats.Diallyltetra, penta-, hexa- and hep- tasulphides are potential antioxidants.Allium leptophyllum Wall. is equated with Vana Lashuna, Jangali Lahsun.Dosage: Bulb—3 g (API Vol. III.)... allium sativumHabitat: Drier parts of India.
English: Almondette tree, Cheron- jee, Buchanan's Mango.Ayurvedic: Priyaala, Piyaala, Kharskandha, Bahulvalkala, Taa- paseshtha, Sannakadru Dhanush- pat, Chaar.Unani/Tamil ? Saaraapparuppu.Siddha: Mudaima, Morala (Tamil).Action: Kernel—laxative, febrifuge. An ointment made out of the kernels is used to cure itch of the skin and to remove blemishes from the face. Oil from kernels— substitute for almond oil. Applied to glandular swellings of the neck. The oil is a promising source of palmitic and oleic acids.
Kernel lipids (65.6%), comprised mainly of neutral lipids (90.4%), consist mostly of triacylglycerol (82.2%), free fatty acids (7.8%) and small amount of diacylglycerols, monoacylglycerols and sterols.The kernels are used in Indian medicine as a brain tonic. The leaves are valued as a cardiotonic.The leaves contain 2.64% tannins (0.35% gallo-tannins). The presence of triterpenoids, saponins, flavonoids and reducing sugars are also reported. Powdered or crushed leaves are applied to wounds.The bark contains 13.40% tannins. The presence of alkaloids, saponins and reducing sugars is also reported.Gum (stem exudate) is antidiar- rhoeal. Used internally in rheumatism.Dosage: Stem bark—5-10 g (API Vol. IV.)... buchanania lanzanAstigmatism (See ASTIGMATISM.)
Blepharitis A chronic in?ammation of the lid margins. SEBORRHOEA and staphylococcal infection are likely contributors. The eyes are typically intermittently red, sore and gritty over months or years. Treatment is di?cult and may fail. Measures to reduce debris on the lid margins, intermittent courses of topical antibiotics, steroids or systemic antibiotics may help the sufferer.
Blepharospasm Involuntary closure of the eye. This may accompany irritation but may also occur without an apparent cause. It may be severe enough to interfere with vision. Treatment involves removing the source of irritation, if present. Severe and persistent cases may respond to injection of Botulinum toxin into the orbicularis muscle.
Cataract A term used to describe any opacity in the lens of the eye, from the smallest spot to total opaqueness. The prevalence of cataracts is age-related: 65 per cent of individuals in their sixth decade have some degree of lens opacity, while all those over 80 are affected. Cataracts are the most important cause of blindness worldwide. Symptoms will depend on whether one or both eyes are affected, as well as the position and density of the cataract(s). If only one eye is developing a cataract, it may be some time before the person notices it, though reading may be affected. Some people with cataracts become shortsighted, which in older people may paradoxically ‘improve’ their ability to read. Bright light may worsen vision in those with cataracts.
The extent of visual impairment depends on the nature of the cataracts, and the ?rst symptoms noticed by patients include di?culty in recognising faces and in reading, while problems watching television or driving, especially at night, are pointers to the condition. Cataracts are common but are not the only cause of deteriorating vision. Patients with cataracts should be able to point to the position of a light and their pupillary reactions should be normal. If a bright light is shone on the eye, the lens may appear brown or, in advanced cataracts, white (see diagram).
While increasing age is the commonest cause of cataract in the UK, patients with DIABETES MELLITUS, UVEITIS and a history of injury to the eye can also develop the disorder. Prolonged STEROID treatment can result in cataracts. Children may develop cataracts, and in them the condition is much more serious as vision may be irreversibly impaired because development of the brain’s ability to interpret visual signals is hindered. This may happen even if the cataracts are removed, so early referral for treatment is essential. One of the physical signs which doctors look for when they suspect cataract in adults as well as in children is the ‘red re?ex’. This is observable when an ophthalmoscopic examination of the eye is made (see OPHTHALMOSCOPE). Identi?cation of this red re?ex (a re?ection of light from the red surface of the retina –see EYE) is a key diagnostic sign in children, especially young ones.
There is no e?ective medical treatment for established cataracts. Surgery is necessary and the decision when to operate depends mainly on how the cataract(s) affect(s) the patient’s vision. Nowadays, surgery can be done at any time with limited risk. Most patients with a vision of 6/18 – 6/10 is the minimum standard for driving – or worse in both eyes should
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bene?t from surgery, though elderly people may tolerate visual acuity of 6/18 or worse, so surgery must be tailored to the individual’s needs. Younger people with a cataract will have more demanding visual requirements and so may opt for an ‘earlier’ operation. Most cataract surgery in Britain is now done under local anaesthetic and uses the ‘phaco-emulsi?cation’ method. A small hole is made in the anterior capsule of the lens after which the hard lens nucleus is liqui?ed ultrasonically. A replacement lens is inserted into the empty lens bag (see diagram). Patients usually return to their normal activities within a few days of the operation. A recent development under test in the USA for children requiring cataract operations is an intra-ocular ?exible implant whose magnifying power can be altered as a child develops, thus precluding the need for a series of corrective operations as happens now.
Chalazion A ?rm lump in the eyelid relating to a blocked meibomian gland, felt deep within the lid. Treatment is not always necessary; a proportion spontaneously resolve. There can be associated infection when the lid becomes red and painful requiring antibiotic treatment. If troublesome, the chalazion can be incised under local anaesthetic.
Conjunctivitis In?ammation of the conjunctiva (see EYE) which may affect one or both eyes. Typically the eye is red, itchy, sticky and gritty but is not usually painful. Redness is not always present. Conjunctivitis can occasionally be painful, particularly if there is an associated keratitis (see below) – for example, adenovirus infection, herpetic infection.
The cause can be infective (bacteria, viruses or CHLAMYDIA), chemical (e.g. acids, alkalis) or allergic (e.g. in hay fever). Conjunctivitis may also be caused by contact lenses, and preservatives or even the drugs in eye drops may cause conjunctival in?ammation. Conjunctivitis may addtionally occur in association with other illnesses – for example, upper-respiratory-tract infection, Stevens-Johnson syndrome (see ERYTHEMA – erythema multiforme) or REITER’S SYNDROME. The treatment depends on the cause. In many patients acute conjunctivitis is self-limiting.
Dacryocystitis In?ammation of the lacrimal sac. This may present acutely as a red, painful swelling between the nose and the lower lid. An abscess may form which points through the skin and which may need to be drained by incision. Systemic antibiotics may be necessary. Chronic dacryocystitis may occur with recurrent discharge from the openings of the tear ducts and recurrent swelling of the lacrimal sac. Obstruction of the tear duct is accompanied by watering of the eye. If the symptoms are troublesome, the patient’s tear passageways need to be surgically reconstructed.
Ectropion The lid margin is everted – usually the lower lid. Ectropion is most commonly associated with ageing, when the tissues of the lid become lax. It can also be caused by shortening of the skin of the lids such as happens with scarring or mechanical factors – for example, a tumour pulling the skin of the lower lid downwards. Ectropion tends to cause watering and an unsightly appearance. The treatment is surgical.
Entropion The lid margin is inverted – usually the lower lid. Entropion is most commonly associated with ageing, when the tissues of the lid become lax. It can also be caused by shortening of the inner surfaces of the lids due to scarring – for example, TRACHOMA or chemical burns. The inwardly directed lashes cause irritation and can abrade the cornea. The treatment is surgical.
Episcleritis In?ammation of the EPISCLERA. There is usually no apparent cause. The in?ammation may be di?use or localised and may affect one or both eyes. It sometimes recurs. The affected area is usually red and moderately painful. Episcleritis is generally not thought to be as painful as scleritis and does not lead to the same complications. Treatment is generally directed at improving the patient’s symptoms. The in?ammation may respond to NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS) or topical CORTICOSTEROIDS.
Errors of refraction (Ametropia.) These will occur when the focusing power of the lens and cornea does not match the length of the eye, so that rays of light parallel to the visual axis are not focused at the fovea centralis (see EYE). There are three types of refractive error: HYPERMETROPIA or long-sightedness. The refractive power of the eye is too weak, or the eye is too short so that rays of light are brought to a focus at a point behind the retina. Longsighted people can see well in the distance but generally require glasses with convex lenses for reading. Uncorrected long sight can lead to headaches and intermittent blurring of vision following prolonged close work (i.e. eye strain). As a result of ageing, the eye becomes gradually long-sighted, resulting in many people needing reading glasses in later life: this normal process is known as presbyopia. A particular form of long-sightedness occurs after cataract extraction (see above). MYOPIA(Short sight or near sight.) Rays of light are brought to a focus in front of the retina because the refractive power of the eye is too great or the eye is too short. Short-sighted people can see close to but need spectacles with concave lenses in order to see in the distance. ASTIGMATISMThe refractive power of the eye is not the same in each meridian. Some rays of light may be focused in front of the retina while others are focused on or behind the retina. Astigmatism can accompany hypermetropia or myopia. It may be corrected by cylindrical lenses: these consist of a slice from the side of a cylinder (i.e. curved in one meridian and ?at in the meridian at right-angles to it).
Keratitis In?ammation of the cornea in response to a variety of insults – viral, bacterial, chemical, radiation, or mechanical trauma. Keratitis may be super?cial or involve the deeper layers, the latter being generally more serious. The eye is usually red, painful and photophobic. Treatment is directed at the cause.
Nystagmus Involuntary rhythmic oscillation of one or both eyes. There are several causes including nervous disorders, vestibular disorders, eye disorders and certain drugs including alcohol.
Ophthalmia In?ammation of the eye, especially the conjunctiva (see conjunctivitis, above). Ophthalmia neonatorum is a type of conjunctivitis that occurs in newborn babies. They catch the disease when passing through an infected birth canal during their mother’s labour (see PREGNANCY AND LABOUR). CHLAMYDIA and GONORRHOEA are the two most common infections. Treatment is e?ective with antibiotics: untreated, the infection may cause permanent eye damage.
Pinguecula A benign degenerative change in the connective tissue at the nasal or temporal limbus (see EYE). This is visible as a small, ?attened, yellow-white lump adjacent to the cornea.
Pterygium Overgrowth of the conjunctival tissues at the limbus on to the cornea (see EYE). This usually occurs on the nasal side and is associated with exposure to sunlight. The pterygium is surgically removed for cosmetic reasons or if it is thought to be advancing towards the visual axis.
Ptosis Drooping of the upper lid. May occur because of a defect in the muscles which raise the lid (levator complex), sometimes the result of ageing or trauma. Other causes include HORNER’S SYNDROME, third cranial nerve PALSY, MYASTHENIA GRAVIS, and DYSTROPHIA MYOTONICA. The cause needs to be determined and treated if possible. The treatment for a severely drooping lid is surgical, but other measures can be used to prop up the lid with varying success.
Retina, disorders of The retina can be damaged by disease that affects the retina alone, or by diseases affecting the whole body.
Retinopathy is a term used to denote an abnormality of the retina without specifying a cause. Some retinal disorders are discussed below. DIABETIC RETINOPATHY Retinal disease occurring in patients with DIABETES MELLITUS. It is the commonest cause of blind registration in Great Britain of people between the ages of 20 and 65. Diabetic retinopathy can be divided into several types. The two main causes of blindness are those that follow: ?rst, development of new blood vessels from the retina, with resultant complications and, second, those following ‘water logging’ (oedema) of the macula. Treatment is by maintaining rigid control of blood-sugar levels combined with laser treatment for certain forms of the disease – in particular to get rid of new blood vessels. HYPERTENSIVE RETINOPATHY Retinal disease secondary to the development of high blood pressure. Treatment involves control of the blood pressure (see HYPERTENSION). SICKLE CELL RETINOPATHY People with sickle cell disease (see under ANAEYIA) can develop a number of retinal problems including new blood vessels from the retina. RETINOPATHY OF PREMATURITY (ROP) Previously called retrolental ?broplasia (RLF), this is a disorder affecting low-birth-weight premature babies exposed to oxygen. Essentially, new blood vessels develop which cause extensive traction on the retina with resultant retinal detachment and poor vision. RETINAL ARTERY OCCLUSION; RETINAL VEIN OCCLUSION These result in damage to those areas of retina supplied by the affected blood vessel: the blood vessels become blocked. If the peripheral retina is damaged the patient may be completely symptom-free, although areas of blindness may be detected on examination of ?eld of vision. If the macula is involved, visual loss may be sudden, profound and permanent. There is no e?ective treatment once visual loss has occurred. SENILE MACULAR DEGENERATION (‘Senile’ indicates age of onset and has no bearing on mental state.) This is the leading cause of blindness in the elderly in the western world. The average age of onset is 65 years. Patients initially notice a disturbance of their vision which gradually progresses over months or years. They lose the ability to recognise ?ne detail; for example, they cannot read ?ne print, sew, or recognise people’s faces. They always retain the ability to recognise large objects such as doors and chairs, and are therefore able to get around and about reasonably well. There is no e?ective treatment in the majority of cases. RETINITIS PIGMENTOSAA group of rare, inherited diseases characterised by the development of night blindness and tunnel vision. Symptoms start in childhood and are progressive. Many patients retain good visual acuity, although their peripheral vision is limited. One of the characteristic ?ndings on examination is collections of pigment in the retina which have a characteristic shape and are therefore known as ‘bone spicules’. There is no e?ective treatment. RETINAL DETACHMENTusually occurs due to the development of a hole in the retina. Holes can occur as a result of degeneration of the retina, traction on the retina by the vitreous, or injury. Fluid from the vitreous passes through the hole causing a split within the retina; the inner part of the retina becomes detached from the outer part, the latter remaining in contact with the choroid. Detached retina loses its ability to detect light, with consequent impairment of vision. Retinal detachments are more common in the short-sighted, in the elderly or following cataract extraction. Symptoms include spots before the eyes (?oaters), ?ashing lights and a shadow over the eye with progressive loss of vision. Treatment by laser is very e?ective if caught early, at the stage when a hole has developed in the retina but before the retina has become detached. The edges of the hole can be ‘spot welded’ to the underlying choroid. Once a detachment has occurred, laser therapy cannot be used; the retina has to be repositioned. This is usually done by indenting the wall of the eye from the outside to meet the retina, then making the retina stick to the wall of the eye by inducing in?ammation in the wall (by freezing it). The outcome of surgery depends largely on the extent of the detachment and its duration. Complicated forms of detachment can occur due to diabetic eye disease, injury or tumour. Each requires a specialised form of treatment.
Scleritis In?ammation of the sclera (see EYE). This can be localised or di?use, can affect the anterior or the posterior sclera, and can affect one or both eyes. The affected eye is usually red and painful. Scleritis can lead to thinning and even perforation of the sclera, sometimes with little sign of in?ammation. Posterior scleritis in particular may cause impaired vision and require emergency treatment. There is often no apparent cause, but there are some associated conditions – for example, RHEUMATOID ARTHRITIS, GOUT, and an autoimmune disease affecting the nasal passages and lungs called Wegener’s granulomatosis. Treatment depends on severity but may involve NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS), topical CORTICOSTEROIDS or systemic immunosuppressive drugs.
Stye Infection of a lash follicle. This presents as a painful small red lump at the lid margin. It often resolves spontaneously but may require antibiotic treatment if it persists or recurs.
Sub-conjunctival haemorrhage Haemorrhage between the conjunctiva and the underlying episclera. It is painless. There is usually no apparent cause and it resolves spontaneously.
Trichiasis Inward misdirection of the lashes. Trichiasis occurs due to in?ammation of or trauma to the lid margin. Treatment involves removal of the patient’s lashes. Regrowth may be prevented by electrolysis, by CRYOTHERAPY to the lid margin, or by surgery.
For the subject of arti?cial eyes, see under PROSTHESIS; also GLAUCOMA, SQUINT and UVEITIS.... eye, disorders of
Habitat: Cultivated throughout India.
English: Taro, EdibleYam.Ayurvedic: Pindaaluka, Aaluki.Siddha/Tamil: Chaembu, Shaeppam- kizhangu.Folk: Arvi, Ghuiyaa.Action: Juice from petiole—styptic, rubefacient. Juice of corn—used in alopaecia.
The leaves contain flavones, api- genin and luteolin, also anthocyanins. Leaves cause severe irritation in mouth. Cooked leaves are a source of dietary fibre for diabetics helping in lowering post-prandial blood glucose level. A significant increase in total lipids, total cholesterol and triglyceride levels was observed in hypercholesterolaemic rats when fed with dried leaf powder.The pressed juice of the petioles is used as an astringent and styptic. All parts of the plant show an acridity. The acridity is removed by boiling and by addition of baking soda.From the tubers two dihydroxys- terols, besides beta-sitosterol and stig- masterol, have been isolated. Five novel aliphatic compounds have been reported. Trypsin inhibitors are isolated from the tubers.The total amino acids recorded in the tubers range from 1380 to 2397 mg/ 100 g. The lysine concentration was relatively low. Besides starch, the tubers contain natural polysaccharides with 56% neutral sugars and 40% anionic components. Steamed corms contain 30% starch and 3% sugar.... colocasia esculentaHabitat: Native to Central America. Cultivated in warmer climate than that required for C. maxima.
English: Squash.Ayurvedic: Kumshmaanda.Action: Fruit—used in headache, bronchitis, asthma; as diuretic in genitourinary disorders; as anthelmintic against tapeworms. Dried pulp is administered in haemptysis.
The lipids isolated from the seeds included glycerides, sterol esters, phos- phatidylcholine and phosphatidylinos- itol. The aqueous extract of seeds showed potent gastroprotective activity against ethanol-induced gastric lesions in rats.In Chinese medicine, Cucurbita mo- schata flower is used in jaundice, dysentery and cough; the root in jaundice, strangury, galactostasis and dysentery; the stem in irregular menstruation and scalds.... cucurbita moschataHabitat: Native to the Mediterranean region; now cultivated in Punjab and Uttar Pradesh.
English: Cumin.Ayurvedic: Shveta-jiraka, Ajaaji, Shukla-ajaaji. The three jirakas mentioned in the Ayurvedic texts are: Jiraka, Krishna Jiraka (Carum bulbocastanum W. Koch.) and Kaaravi (Carum carvi Linn.).Unani: Safed Jeeraa, Kamun.Siddha/Tamil: Cheerakam.Action: Carminative, antispasmodic (used in dyspepsia and diarrhoea), stimulant, diuretic, antibacterial, emmenagogue, galactagogue.
Cumin seeds contain up to 14.5% lipids. They are reported to contain 14 flavonoid glycosides; 7 belong to api- genin, 5 to luteolin and 2 to chrysoeri- ol group. Major constituents of the essential oil include cuminaldehyde (2040% of the oil) and p-cymene.EtOH (50%) extract of the fruit exhibits spasmolytic and hypotensive activity.Cumin is considered superior is comforting carminative qualities to Fennel or Caraway. Due to its disagreeable flavour it has been replaced by Caraway in European herbal medicine.Cumin oil and cuminaldehyde have been reported to exhibit strong larvi- cidal and antibacterial activity.Fine grinding of the seed can cause loss of 50% of volatile oil, most within one hour. (Natural Medicines Comprehensive Database, 2007.)Dosage: Fruit—1-3 g powder. (API Vol. I.)... cuminum cyminumDiagnosis depends on blood tests.
Treatment aims to reduce blood lipid levels, usually by a low-fat diet and lipid-lowering drugs.... hyperlipidaemias
Habitat: Cultivated in Gujarat; wild in parts of West Bengal, Uttar Pradesh, Karnataka and Tamil Nadu.
English: Mango-ginger, Wild Turmeric.Ayurvedic: Aamra Haridraa, Aam- ragandhi Haridraa, Surabhidaaru, Karpuraa.Unani: Aambaa Haldi, Daarchob.Siddha/Tamil: Mangaiinji.Action: Carminative, stomachic, appetizer, expectorant, antipyretic, anti-inflammatory. Specific in rheumatism and inflammation of liver; rheumatism; in contusions and sprains.
Presence of curcumin and a phytos- terol is reported in the rhizome. The essential oil exhibited antimicrobial, antifungal and anthelmintic activity against tape worms.Significant decrease was observed in liver total lipids and serum triglycerides of adult female rat when fed 10% Mango-ginger or 10% curcumin along with normal diet or a surcose- based hypertriglyceridaemic diet.Dosage: Rhizome—3-5 g powder; 10-20 ml juice. (CCRAS.)... curcuma amadaHabitat: The sub-Himalayan tract, up to 1,200 m from Indus to Assam and in plains throughout India.
English: Sissoo, South Indian Redwood, Sissoo.Ayurvedic: Shimshapaa, Krishna- shimshapaa, Picchilaa.Unani: Seesham.Siddha/Tamil: Irupoolai.Action: Leaves—bitter, and stimulant. Leaf mucilage, mixed with sweet oil, is applied to excoriations. Wood—anthelmintic, alterative, emetic, stomachic, antileprotic; used in diseases due to vitiated blood. Bark—anticholerin. Root—astringent.
Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicated the use of the heart- wood in turbity of the urine, calculus and lipuria.The leaves gave isoflavone sissotrin; flowers 7,4'-di-Me-tectorigenin. Seed oil (4.1%) contained fatty acids composed of palmitic (16.2), stearic (7.0%), oleic (14.6), linolenic (9.80) and linole- ic (52.5) acids and lipids comprising neutral lipids (88.5), glycolipids (7.2) and phospholipids (4.0%). Pods contain 2% tannins.Dosage: Heartwood—1.5-10 g powder; 10-20 g for decoction. (API Vol. III.)... dalbergia sissooHabitat: Cultivated mainly in Maharashtra, Madhya Pradesh, Karnataka, Tamil Nadu and Andhra Pradesh.
English: Barnyard Millet.Ayurvedic: Ambah Shyaamaaka.Siddha/Tamil: Oathupul.Folk: SamakAction: Whole plant—used for diseases of the spleen and for checking haemorrhage.
The grains are rich in carbohydrates (3.474 wt %) and trace elements (Cu, Cd, Cr, Ni, Fe, Mn, Sn). The total protein content is 4.2 wt% and the total lipids 4.46%. A hormone, oestrogen, is reported from the lipid.A polysaccharide extracted from the endosperm and composed of glucose was identified as a phytoglycogen.... echinochloa crus-galliHabitat: The Himalayas up to 1,200 m and in plains of India.
English: Trailing indigo.Ayurvedic: Vaasukaa.Siddha/Tamil: Cheppunerinjil.Folk: Hanumaan-buuti, Bhui-nila.Action: Juice of the plant— antiscorbutic, diuretic, alterative. The plant, boiled with oil, is applied to burns. A decoction is given in epilepsy and insanity.
The plant contains two unsaturat- ed hydrocarbons—indigoferin and en- neaphyllin. The seeds contain 37.8% protein, also yield lipids (4.4%) containing palmitic and oleic acid. The toxicity of the plant is attributed to a non-protein amino acid, indospicine (6-amidino-2-aminohexanoic acid). (Consumption of the plant produces a neurological syndrome, known as Birdsville disease, in horses. The toxic- ity is greatly reduced when the material is chopped and dried.)The aerial parts gave 3-nitropropa- noyl esters of D-glucose.... indigofera enneaphyllaThe most common lipid disorders are the hyperlipidaemias, which are characterized by high levels of lipids in the blood and can cause atherosclerosis and pancreatitis.
There are also some very rare lipid disorders due solely to heredity, such as Tay–Sachs disease.... lipid disorders
cholesterol in the bloodstream. An excess of LDLs (see hyperlipidaemias) is associated with atherosclerosis. (See also high density lipoprotein.)... low density lipoprotein
Habitat: Throughout the warmer parts of India.
Ayurvedic: Granthiparni, Kaaka- puchha.Folk: Gathivan, Deepamaal (Maharashtra).Action: Leaves—spasmolytic. Ash of flower head—applied to burns and scalds, in ringworm and other skin diseases.
The Ayurvedic Pharmacopoeia ofIn- dia recommends the root in cough, bronchitis and dyspnoea.The root contains n-octacosanol, n-octacosanoic acid, quercetin, 4,6,7- trimethoxy-5-methylchromene-2-one, campesterol and beta-sitosterol-beta- D-glucopyranoside.The plant contains 4,6,7-trimethoxy- 5-methyl-chromene-2-one.The leaves contain neptaefolin, nep- taefuran, neptaefuranol, neptaefolinol, leonitin, neptaefolinin and (-)-55, 6- octadecadienoic acid.The seed oil contains oleic, linoleic, palmitic and stearic acids. The fattyFamily: Labiatae; Lamiaceae.Habitat: Native to Europe; also distributed in Himalayas from Kashmir to Kumaon.
English: Common Motherwort, Lion's Tail.Unani: Baranjaasif. (Also equated with Artemesia vulgaris Linn; and Achillea millifolium Linn.)Action: Stomachic, laxative, antispasmodic, diaphoretic, em- menagogue (used in absent or painful menstruation, premenstrual tension, menopausal flushes). Hypnotic, sedative. Used as a cardiac tonic. (Studies in China have shown that Motherwort extracts show antiplatelet aggregation actions and decrease the levels of blood lipids.)
Key application: In nervous cardiac disorders and as adjuvant for thyroid hyperfunction. (German Commission E.) As antispasmodic. (The British Herbal Pharmacopoeia.) The British Herbal Compendium indicated its use for patients who have neuropathic cardiac disorders and cardiac complaints of nervous origin.The plant contains diterpene bitter principles, iridoid monoterpenes, flavonoids including rutin and querci- trin, leonurin, betaine, caffeic acid derivatives, tannins and traces of a volatile oil.The herb is a slow acting adjuvant in functional and neurogenic heart diseases. Its sedative and spasmolytic properties combine well with Valeriana officinalis or other cardioactive substances.The herb contains several components with sedative effects—alpha- pinene, benzaldehyde, caryophyllene, limonene and oleanolic acid. (Sharon M. Herr.)Habitat: Western Europe. Seeds are imported into India from Persia.
English: Pepper-Grass.Unani: Bazr-ul-khumkhum, Todari (white var.).Action: Seeds—blood purifier; prescribed in bronchitis.
The fatty acid of the oil are: oleic 12.9, linoleic 47.87, linolenic 5.43, erucic 31.97, stearic 0.54 and palmitic 1.22%.The seed mucilage on hydrolysis gave galactose, arabinose, rhamnose and galacturonic acid.Flowering tops and seeds contain a bitter principle, lepidin.The plant yield a sulphur-containing volatile oil.... leonurus cardiacaHabitat: Cultivated mainly in Madhya Pradesh, Uttar Pradesh, Maharashtra, Bihar and Rajasthan.
English: Linseed, Flax.Ayurvedic: Atasi, Umaa, Masrnaa, Nilapushpi, Kshumaa.Unani: Kattan.Siddha/Tamil: (Seed).Action: Seed—demulcent, emollient, laxative, antilipidemic, antitussive, pectoral (used in bronchitis and cough). Flowers—used as nervine and cardiac tonic. Oil— used in burns, skin injuries and sores.
Key application: Internally, for chronic constipation, for colons damaged by abuse of laxatives, irritable bowel syndrome, diverticular disease, symptomatic short-term treatment of gastritis and enteritis. Externally, for painful skin inflammations. (German Commission E, ESCOP, The British Herbal Pharmacopoeia.)The plant contains chlorogenic acid and its isomer. Also present are palmitic, stearic, oleic, linoleic acids, along with amino acids, and sugars. Linseed also contains mucilage (3-10%) in epidermis; fatty oil (30-40%); cyanogenic glycosides (0.05-00.1%) mainly linus- tatin, neolinustatin and linamarin; lig- nans; phenylpropane derivatives including linusitamarin. (Cyanogenic glycosides are not found toxic in therapeutic doses as these are broken down only to a limited extent in the body.)The seeds are an excellent source of dietary alpha-linolenic acid for modifying plasma and tissue lipids. Flaxseed preparations reduced atherogenic risk in hyperlipemic patients. (Cited in Expanded Commission E Monographs.)Human studies have indicated Flax- seed's use in atherosclerosis, hyperc- holesterolemia, lupus nephritis, chronic renal diseases and in cancer prevention (active principle: lignan precursor secoisolariciresinol diglycoside). (Sharon M. Herr. Also Am J Clin Nutr, 1999, 69, 395-402.)The PP glucose response to a 50 g carbohydrate load given as Flaxseed bread was found to be 27% lower when compared with regular white bread.Taking Flaxseed oil daily for 3 months did not improve symptoms of pain and stiffness in rheumatoid arthritis and no effect was observed on RA, such as C-reactive protein and ESR. (Natural Medicines Comprehensive Database, 2007.)The water-binding capacity and rhe- ological properties of linseed mucilage resembled those of guar gum.Dosage: Ripe seed—3-6 g powder. (API, Vol. I.) Flower-bud—3-6 g; oil—5-10 ml. (CCRAS.)... linum usitatissimumHabitat: Native to China; now cultivated mainly in Northern Bihar, particularly in Muzaffarpur and Darbhanga districts, and Saharanpur, Dehra Dun, Muzaffar- nagar, Gorakhpur, Deoria, Gonda, Basti, Faizabad, Rampur, Bareil- ly, Bahraich, Kheri and Pilibhit districts of Uttar Pradesh.
English: Litchi, Lychee.Action: Fruit—refrigerant during summer. Leaf—used in bites of animals.
Litchi aril contains: total sugars (as invert sugar) 12.1-14.8; reducing sugar 9-13.7; non-reducing sugar 1.0-3.4; acidity (as citric acid) 0.22-0.36%; and ascorbic acid 34.5-45.4 mg/100 g.The plant contains levulinic, malic, citric, lactic, malonic, fumaric, suc- cinic, phosphoric and glutaric acids.The Bark contains friedelin and stig- masterol.Litchi seeds are prescribed in Malaya for neurological disorders and orchi- tis. In seed lipids, fatty acids cyclo- propanoic 42.0; oleic 27.0, palmitic 12.0 and linoleic 11.0%, have been determined.... litchi chinensisOne of the major problems of the menopause which does not give rise to symptoms until many years later is osteoporosis (see BONE, DISORDERS OF). After the menopause, 1 per cent of the bone is lost per annum to the end of life. This is a factor in the frequency of fractures of the femur in elderly women as a result of osetoporosis, but it can be prevented by hormone replacement therapy (see below).
Hormone replacement therapy (HRT) This term has become synonymous with the scienti?cally correct term ‘OESTROGENS replacement therapy’ to signify the treatment of menopausal symptoms and signs with oestrogens, now usually combined with PROGESTOGEN. Oestrogen and combined treatment relieve the short-term symptoms such as hot ?ushes, sweats and vaginal dryness. Atrophic vaginitis and vulvitis (shrinking of the tissues of VULVA and VAGINA due to fall in natural oestrogen levels) also usually respond to treatment with oestrogens.
Cyclical therapy is necessary to avoid abnormal bleeding in women who have reached the menopause. If oestrogens are given alone, there is an increased risk of endometrial hyperplasia (overgrowth of the ENDOMETRIUM) which may lead to endometrial cancer, so these are restricted to women who have had a hysterectomy and are no longer at risk. Other women can be given oestrogen-progestogen combinations.
There is good evidence that oestrogen alone or in combination can prevent the bone-loss associated with the menopause by reducing the demineralisation of bone which normally occurs after the menopause; and, if it is started early and continued for years, it may prevent the development of osteoporosis. Oestrogen is far more e?ective than calcium supplements and has been shown greatly to reduce fractures affecting the spine, wrists and legs after the age of 50.
However, HRT is no longer licensed for ?rst-line treatment to prevent osteoporosis, as increased risk of stroke, breast cancer and coronary heart disease cannot justify treatment for long periods – unless the woman has severe menopausal symptoms. HRT is recommended for short-term use only in menopausal women whose lives are inconvenienced by vasomotor instability (severe ?ushes, etc.) or vaginal atrophy, although the latter may respond to local oestrogen treatment – creams or pessaries. In terms of oestrogenic activity, natural oestrogen such as oestradiol, oestrone and oestriol are more appropriate for HRT than synthetic oestrogens like ethinyloestradiol, mestranol and diethylstilboestrol.
Many experts believe that controversy surrounding the risks and bene?ts of HRT have been settled by a large randomised trial (the Women’s Health Initiative), published in 2003, which showed that combined treatment increases the risk of breast tumours, stroke and coronary heart disease (in the ?rst year). Oestrogen alone (given to women who have had a hysterectomy) also increases the risk of stroke. Five years of combined treatment may double the risk of breast cancer, and the heart-disease risk is nearly doubled during the ?rst year of use. This is in spite of the bene?cial effects of HRT on blood lipids. However, there are others who consider that di?erent dose combinations of di?erent hormones may one day prove bene?cial, so research continues.
HRT can also provoke minor adverse effects such as breast tenderness, ?uid retention, leg cramps and nausea. The risk of abnormal blood clotting means that HRT is not normally recommended for women who smoke heavily or have had THROMBOSIS, severe HYPERTENSION, stroke or liver disease. HRT has, however, brought symptomatic bene?ts to many menopausal women, who can then justify taking the other increased risks – only fully understood since the large trial results were published.
As the evidence stands at present, careful consideration of each woman’s medical history and the severity of her menopausal symptoms is necessary in deciding what combination of drugs should be given and for how long. In general, the indications should be severe menopausal symptoms that can be controlled by the lowest dose for the shortest time. Using HRT to alleviate mild symptoms, or to prevent future bone loss, is probably of insu?cient bene?t to counter the other risks described above.... menopause
Habitat: Native to Eurasia; cultivated in Kashmir, Kumaon and Himachal Pradesh.
English: Sweet Cherry.Ayurvedic: Elavaaluka, Elaya, Harivaaluka.Folk: Gilaas, Krusbal.Action: Fruit stalks—diuretic, antiinflammatory, astringent, used for oedema, inflammation of urinary tract, cystitis, nephritis, urinary retention.
The stems contain salicylic acid, organic acids tannins and potassium salts. Protocatechuic, p-coumaric, fer- ulic and diferculic acids have been identified in the shoots.The fruit contains salicylates and cyanogenic glycosides, and vitamin A, B1 and C. Sugars consist mainly of glucose and fructose, with sucrose as a minor component. Malic acid is the principal acid, small amounts of citric, tartaric and succinic acids are also reported. The lipids of the fruit pulp contain cis-vaccenic acid.The acetone extract of peduncle gave an isoflavone, prunetin, which on hydrolysis yielded an aglycone identified as prunetin and sugar as glucose.The seeds contain a cyanogenic gly- coside and are toxic. The bark contains tannins up to 16%.Dosage: Seed—3-5 g powder. (CCRAS.)... prunus aviumHabitat: Waste places and fields throughout India, up to an altitude of 2,400 m.
English: Corn Sow Thistle.Ayurvedic: Sahadevi (bigger var.). (Vernonia cinerea is equated with Sahadevi.)Action: Plant—sedative, hypnotic, anodyne, expectorant, diuretic. Used for nervous debility. Seeds— used for asthma, bronchitis, cough, pertussis, fever; decoction in insomnia. Leaves—applied to swellings. Root—used for diseases of the respiratory tract.
The plant contains amino acids, lipids, polymeric hydrocarbons, polyphenols, protein; alpha- and beta- amyrins, lupeol, pseudotaraxasterol, taraxasterol. The latex contains manni- tol, alpha-and beta-lactucerols. Aerial parts and fruits contain ceryl alcohol, choline, palmitic, tartaric and stearic acids.... sonchus arvensisHabitat: Tropical India and the Andamans.
Ayurvedic: Guduuchi, Gudu- uchikaa, Guluuchi, Amrita, Am- ritaa, Amritalataa, Amritavalli, Chinnaruuhaa, Chinnodbhavaa, Madhuparni, Vatsaadani, Tantrikaa, Kundalini. Guduuchi sattva (starch).Unani: Gilo, Gulanchaa. Sat-e-Gilo (starch).Siddha: Seenil, Amrida-valli.Folk: Giloya.Action: Herb—antipyretic, an- tiperiodic, anti-inflammatory, antirheumatic, spasmolytic, hypo- glycaemic, hepatoprotective. Water extract increases urine output. Stem juice—prescribed in high fever; decoction in rheumatic and bilious fevers. Aqueous extract of the plant—fabrifuge. Starch—antacid, antidiarrhoeal and antidysenteric.
The Ayurvedic Pharmacopoeia of India, along with other therapeutic applications, recommends the dried stems in jaundice, anaemia, polyuria and skin diseases.The stem contains alkaloidal constituents, including berberine; bitter principles, including columbin, chas- manthin, palmarin and tinosporon, tinosporic acid and tinosporol.The drug is reported to possess one- fifth of the analgesic effect of sodium salicylate. Its aqueous extract has a high phagocytic index.Alcoholic extract of the stem shows activity against E. coli. Active principles were found to inhibit in vitro the growth of Mycobacterium tuberculosis.Oral administration of alcoholic extract of the root resulted in a significant reduction in blood and urine glucose and in lipids in serum and tissues of alloxan diabetic rats. (Phytother Res. 2003 17 (4), 410-3.)A significant reduction in levels of SGOT, SGPT, ALP and bilirubin were observed following T. cordifolia treatment during CCl4 intoxication in mature rats. (J. Toxicol Sci. 2002, 27 (3), 139-46.) The plant extract showed in vitro inactivating activity in Hepatitis- B surface antigen. (Indian Drugs, 1993, 30, 549.)A new hypoglycaemic agent was isolated from the plant; it was found to be 1,2-substituted pyrrolidine.The starch from roots and stem, used in chronic diarrhoea and dysentery, contains a polysaccharide having 1-4 glucan with occasional branching points.Dosage: Stem—3-6 g powder; 2030 g for decoction. (API, Vol. I.)... tinospora cordifoliaHabitat: Widely cultivated in many parts of India.
English: Fenugreek.Ayurvedic: Methikaa, Methi, Vastikaa, Selu, Methini, Dipani, Bahupatrikaa, Bodhaini, Gand- haphala.Unani: Hulbaa, Methi.Siddha/Tamil: Vendhayam.Action: Seeds—used in loss of appetite, flatulence, dyspepsia, colic; diarrhoea, dysentery; enlargement of liver and spleen; and as a lactagogue and puerperal tonic.
Key application: German Commission E reported secretolytic, hypermic and mild antiseptic activity of the seed. The British Herbal Pharmacopoeia reported its actions as demulcent and hy- poglycaemic. ESCOP and WHO monographs indicate the use of seeds in adjuvant therapy for diabetes mellitus, anorexia, also in hypercholesterolemia.The seeds gave alkaloids, including trigonelline, gentianine and carpaine; saponins, based mainly on the sa- pogenins, diosgenin and its isomer yamogenin, gitogenin and tigogenin; flavonoids, including vitexin and its glycosides and esters and luteolin; a volatile oil in small quantities. The mucilage (25-30%) is mostly a galac- tomannan.A C-steroidal sapogenin peptide ester, fenugreekine, exhibited hypogly- caemic activity.About 80% of the total content of free amino acids in the seeds is present as 4-hydroxyisoleucine, which appears to directly stimulate insulin. (Eur J Pharmacol, 390, 2000; Natural Medicines Comprehensive Database, 2007.)Saponin rich extracts reduce blood levels of the cholesterol. The fibrous fraction of seeds also causes a reduction in blood lipids.The aqueous extract is demulcent, promoted healing of gastric ulcers produced experimentally in rats and exhibited a smooth muscle relaxing effect in rabbits without affecting either the heart or blood pressure.Fenugreek has been reported to stimulate the liver microsomal cy- tochrome P450 dependent aryl hy- droxylase and cytochrome b5 in rats; increased bile secretion has also been observed.Fenugreek extract containing trigo- nelline and trigonellic acid maybe used as a hair growth stimulant.Dosage: Seed—3-5 g powder. (CCRAS.)... trigonella foenum-graecumHabitat: Cultivated as a food crop mainly in Punjab, Haryana, Uttar Pradesh., Madhya Pradesh, Maharashtra, Bihar and Rajasthan.
English: Wheat.Ayurvedic: Godhuuma.Folk: Gehun.Action: Wheat germ oil is rich in tocopherol (vitamin E) content, total tocopherols 1897 mcg/g, alpha tocopherol 67%. The presence of ergosterol (provitamin D) has also been reported.
Wheat germ is also used for its minerals, proteins and lipid contents. Germ proteins are rich in lysine (5.285.55 g/100 g protein) and possess high biological value (94%) and protein efficiency ratio (2.9).Wheat germ contains haemaggluti- nating and antipyretic factors, but these are destroyed by toasting. It also contains haemoproteins, possessing per- oxidase activity.In adult rats, addition of wheat germ (7%) to a high fat (cholesterol) diet significantly decreased VLDL-cholesterol and VLDL-triglycerides and increased the HDL-cholesterol after-7 weeks of feeding.Bran oil contains tocopherols, but major part of them (68%) is in epsilon form; alpha-tocopherol forms only 11% of the total.Gluten lipids, associated with gluten, contain a high percentage of linoleic acid; lowering of serum cholesterol level has been observed in experiments (lipid-free gluten is devoid of cholesterol-lowering effect).Sensitivity to gluten has also been reported (even when whole wheat flour was used).... triticum aestivumWhen fatty deposits occur in various parts of the body – skin, brain, cornea, internal organs and tendons – the condition is called xanthomatosis. Treatment is of the underlying conditions, an important aim being to lower the concentrations of fats in the body.
Xanthomata have a variety of manifestations which may point to the underlying cause. These include:
Eruptive Eruptive yellow papules on the buttocks.
Plane Yellow plaques or macules in the skin.
Tuberous Nodules on the elbows or knees.
Tendinous Subcutaneous nodules ?xed to tendons, particularly those on the back of the ?ngers and the ACHILLES TENDON.... xanthoma
Coronary thrombosis is more common in the West because of its preference for animal fats; whereas in the East fats usually take the form of vegetable oils – corn, sunflower seed, sesame, etc. Fatty deposits (atheroma) form in the wall of the coronary artery, obstructing blood-flow. Vessels narrowed by atheroma and by contact with calcium and other salts become hard and brittle (arterio-sclerosis) and are easily blocked. Robbed of oxygen and nutrients heart muscle dies and is replaced by inelastic fibrous (scar) tissue which robs the heart of its maximum performance.
Severe pain and collapse follow a blockage. Where only a small branch of the coronary arterial tree is affected recovery is possible. Cause of the pain is lack of oxygen (Vitamin E). Incidence is highest among women over 40 who smoke excessively and who take The Pill.
The first warning sign is breathlessness and anginal pain behind the breastbone which radiates to arms and neck. Sensation as if the chest is held in a vice. First-line agent to improve flow of blood – Cactus.
For cholesterol control target the liver. Coffee is a minor risk factor.
Measuring hair calcium levels is said to predict those at risk of coronary heart disease. Low hair concentrations may be linked with poor calcium metabolism, high aortic calcium build-up and the formation of plagues. (Dr Allan MacPherson, nutritionist, Scottish Agricultural College, Ayr, Scotland)
Evidence has been advanced that a diagonal ear lobe crease may be a predictor for coronary heart disease. (American Journal of Cardiology, Dec. 1992)
Tooth decay is linked to an increased risk of coronary heart disease and mortality, particularly in young men. (Dr Frank De Stefano, Marshfield Medical Research Foundation, Wisconsin, USA) Treatment. Urgency. Send for doctor or suitably qualified practitioner. Absolute bedrest for 3 weeks followed by 3 months convalescence. Thereafter: adapt lifestyle to slower tempo and avoid undue exertion. Stop smoking. Adequate exercise. Watch weight.
Cardiotonics: Motherwort, Hawthorn, Mistletoe, Rosemary. Ephedra, Lily of the Valley, Broom.
Cardiac vasodilators relax tension on the vessels by increasing capacity of the arteries to carry more blood. Others contain complex glycosides that stimulate or relax the heart at its work. Garlic is strongly recommended as a preventative of CHD.
Hawthorn, vasodilator and anti-hypertensive, is reputed to dissolve deposits in thickened and sclerotic arteries BHP (1983). It is believed to regulate the balance of lipids (body fats) one of which is cholesterol.
Serenity tea. Equal parts: Motherwort, Lemon Balm, Hawthorn leaves or flowers. 1 heaped teaspoon to each cup boiling water; infuse 5-15 minutes; 1 cup freely.
Decoction. Combine equal parts: Broom, Lily of the Valley, Hawthorn. 1-2 teaspoons to each cup water gently simmered 20 minutes. Half-1 cup freely.
Tablets/capsules. Hawthorn, Motherwort, Cactus, Mistletoe, Garlic.
Practitioner. Formula. Hawthorn 20ml; Lily of the Valley 10ml; Pulsatilla 5ml; Stone root 5ml; Barberry 5ml. Tincture Capsicum 1ml. Dose: Powders: 500mg (two 00 capsules or one-third teaspoon). Liquid extracts: 1 teaspoon. Tinctures: 2 teaspoons. Thrice daily in water or honey.
Prevention: Vitamin E – 400iu daily.
Diet. See: DIET – HEART AND CIRCULATION.
Supplements. Daily. Vitamin C, 2g. Vitamin E possesses anti-clotting properties, 400iu. Broad spectrum multivitamin and mineral including chromium, magnesium selenium, zinc, copper.
Acute condition. Strict bed-rest; regulate bowels; avoid excessive physical and mental exertion. Meditation and relaxation techniques dramatically reduce coronary risk. ... coronary heart disease
“It is believed that oxidation of the lipids by free radicals (which are also present in high numbers in patients who have Dupuytren’s contracture) produces toxins which kill fibroblast cells in the palmar fascia. The surrounding tissue overreacts by producing many more fibroblasts, a bit like callous formation after a wound. The rapid increase in fibrous tissue leads to the contracture. This explains why the contracture is so common among patients with diabetes, epilepsy and alcoholism – serum lipid levels are raised in all these groups . . . However, the disorder occurs only if the patient has a genetic predisposition to the disease.” (Mr Paul Sanderson, Orthopaedic Surgeon, Wrightington Hospital, Wigan, in the Journal of Bone and Joint Surgery, Nov. 1992)
Treatment. Directed towards prevention. Same as for HYPERLIPIDAEMIA.
DWARF BEAN. See: FRENCH BEAN.
DWARF ELDER. Danewort. Ground Elder. Sambucus ebulus L. French: Petit sureau. German:
Attichwurzel. Spanish: Sauro enano. Italian: Ebbio. Part used: leaves. Action: expectorant, diaphoretic, diuretic, purgative.
Uses: Dropsy, kidney and bladder torpor, rheumatism.
Combine, equal parts Dwarf Elder, Greater Plantain and Parsley Piert for gravel.
Combine, equal parts Dwarf Elder, Wild Carrot, Broom and Motherwort for oedema of heart origin. Combine, equal parts Dwarf Elder and Celery seeds for polymyalgia and rheumatism. (W.T. Hewitt, FNIMH)
Preparations: Thrice daily.
Tea. 2 teaspoons leaves to each cup boiling water; infuse 10 minutes. Half-1 cup.
Tincture. 1 part in 5 parts 45 per cent alcohol. Macerate 8 days. Decant. 5-10ml (1-2 teaspoons). ... dupuytren’s contracture
Causes. Diet of too much animal fat, smoking, overweight, little exercise.
Symptoms. Same as those for ischaemic heart disease, acute pancreatitis, indigestion, abdominal pain. Alternatives. Hawthorn berries, Lime flowers, Goat’s Rue. Garlic – raw bulb with salads or 2-3 capsules at night. Herb Purslane (Portulaca oleracae): rich in EFA’s (essential fatty acids) in general, and EPA in particular.
Garlic powder significantly reduces serum cholesterol and triglyceride levels in hyperlipidaemia. (German Association of General Practitioners, Study Group on Phytotherapy)
Guar gum. Lowers serum fat levels, body weight and blood pressure: see entry. Add Hawthorn for angina; Goat’s Rue for diabetes; Ispaghula seeds (Regulan) for intestinal and bowel health and to reduce blood-fats.
Fenugreek seeds. Lowers blood cholesterol levels in healthy people and in diabetics. Contain galacto- mannan which aids fat digestion.
Diet. Low fat. High-complex carbohydrate diet. Sugar and refined starches raise but Oats and Bran lower cholesterol levels. High levels reduced by oleic acid (Olive oil). French research workers claim three apples a day can lower plasma and liver cholesterol levels by as much as 30 per cent. The effect is believed to be due to vegetable fibre, especially pectin. Those who stopped eating their three apples after the trial showed a return to higher levels. Replace unsaturated with vegetable polyunsaturated fats. Two or three fatty fish meals weekly to prevent clumping of platelets. Linseed, Grape juice, Artichokes. See entry – OILY FISH.
Supplement: Nicotinic acid.
Stop smoking. Limit intake of alcohol. ... hyperlipidaemia
There are usually no symptoms in the early stages of atherosclerosis. Later, symptoms are caused by reduced or total absence of a blood supply to the organs supplied by the affected arteries. If the coronary arteries, which supply the heart muscle, are partially blocked, symptoms may include the chest pain of angina. If there is complete blockage in a coronary artery, a sudden, often fatal, heart attack may occur. Many strokes are a result of atherosclerosis in the arteries that supply blood to the brain. If atherosclerosis affects the leg arteries, the 1st symptom may be cramping pain when walking due to poor blood flow to the leg muscles. If the condition is associated with an inherited lipid disorder (see hyperlipidaemias), fatty deposits may develop on tendons or under the skin in visible lumps.
The risk of developing atherosclerosis is determined largely by the level of cholesterol in the bloodstream, which depends on dietary and genetic factors. Athersclerosis is most common in Western countries, where most people eat a diet high in fat. Some disorders such as diabetes mellitus can be associated with a high cholesterol level regardless of diet. Blood flow through an artery can be investigated by angiography or Doppler ultrasound scanning.
The best treatment for atherosclerosis is to prevent it from progressing by following a healthy lifestyle. This includes eating a low-fat diet, not smoking, exercising regularly, and maintaining the recommended weight for height. These measures lead to a lower-than-average risk of developing significant atherosclerosis. People found to have high blood cholesterol but who are otherwise in good health will be advised to adopt a low-fat diet. They may also be given drugs that decrease blood cholesterol levels (see lipid-lowering drugs). For people who have had a heart attack, research has shown that there may be a benefit in lowering blood cholesterol levels, even if the level is within the average range for healthy people.
People who have atherosclerosis and are experiencing symptoms of the condition may be prescribed a drug such as aspirin to reduce the risk of blood clots forming on the damaged artery lining.
Surgical treatment such as coronary angioplasty (see angioplasty, balloon) may be recommended for those people thought to be at high risk of severe complications. If blood flow to the heart is severely obstructed, a coronary bypass operation to restore blood flow may be carried out.... atherosclerosis
Fats are usually solid at room temperature; oils are liquid. The amount and types of fat in the diet have important implications for health. A diet containing a large amount of fat, particularly saturated fat, is linked to an increased risk of atherosclerosis and subsequent heart disease and stroke.
Some dietary fats, mainly triglycerides (combinations of glycerol and 3 fatty acids), are sources of the fat-soluble vitamins A, D, E, and K and of essential fatty acids. Triglycerides are the main form of fat stored in the body. These stores act as an energy reserve and also provide insulation and a protective layer for delicate organs. Phospholipids are structural fats found in cell membranes. Sterols, such as cholesterol, are found in animal and plant tissues; they have a variety of functions, often being converted into hormones or vitamins.
Dietary fats are first emulsified by bile salts before being broken down by lipase, a pancreatic enzyme. They are absorbed via the lymphatic system before entering the bloodstream.Lipids are carried in the blood bound to protein; in this state they are known as lipoproteins. There are 4 classes of lipoprotein: very low-density lipoproteins (VLDLs), low-density lipoproteins (LDLs), high-density lipoproteins (HDLs), and chylomicrons. LDLs and VLDLs contain large amounts of cholesterol, which they carry through the bloodstream and deposit in tissues. HDLs pick up cholesterol and carry it back to the liver for processing and excretion. High levels of LDLs are associated with atherosclerosis, whereas HDLs have a protective effect. (See also nutrition.)... fats and oils
Complex organisms are built up of millions of cells that are specially adapted to carry out particular functions. The process of cell differentiation begins early on in the development of the embryo and cells of a particular type (e.g. blood cells, liver cells) always give rise to cells of the same type. Each cell has a particular number of *chromosomes in its nucleus. The sex cells (sperm and ova) always contain half the number of chromosomes of all the other cells of the body (see meiosis); at fertilization a sperm and ovum combine to form a cell with a complete set of chromosomes that will develop into the embryo.... cell
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