Lentigo Health Dictionary

Laser stands for Light Ampli?cation by Stimulated Emission of Radiation. The light produced by a laser is of a single wavelength and all the waves are in phase with each other, allowing a very high level of energy to be projected as a parallel beam or focused on to a small spot.

Various gases, liquids and solids will emit light when they are suitably stimulated. A gassed laser is pumped by the ionising e?ect of a high-voltage current. This is the same process as that used in a ?uorescent tube. Each type of laser has a di?erent e?ect on biological tissues and this is related to the wavelength of the light produced. The wavelength determines the degree of energy absorption by di?erent tissues, and because of this, di?erent lasers are needed for di?erent tasks. The argon laser produces light in the visible green wavelength which is selectively absorbed by HAEMOGLOBIN. It heats and coagulates (see COAGULATION) tissues so can be used to seal bleeding blood vessels and to selectively destroy pigmented lesions. The carbon-dioxide laser is the standard laser for cutting tissue: the infra-red beam it produces is strongly absorbed by water and so vaporises cells. Thus, by moving a ?nely focused beam across the tissue, it is possible to make an incision.

The two main uses of laser in surgery are the endoscopic (see ENDOSCOPE) photocoagulation of bleeding vessels, and the incision of tissue. Lasers have important applications in OPHTHALMOLOGY in the treatment of such disorders as detachment of the retina and the diabetic complications of proliferative retinopathy and of the cornea (see EYE, DISORDERS OF). The destruction of abnormal cells – a sign of pre-malignancy – in the CERVIX UTERI is done using lasers. The beams may also be used to remove scar tissue from the FALLOPIAN TUBES resulting from infection, thus unblocking the tubes and improving the chances of CONCEPTION. Lasers also have several important applications in DERMATOLOGY. They are used in the treatment of pigmented lesions such as LENTIGO, in the obliteration of port-wine stains, in the removal of small, benign tumours such as verrucas, and ?nally in the removal of tattoos.

Low-intensity laser beams promote tissue healing and reduce in?ammation, pain and swelling. Their e?ect is achieved by stimulating blood and lymph ?ow and by cutting the production of PROSTAGLANDINS, which provoke in?ammation and pain. The beams are used to treat ligament sprains, muscle tears and in?amed joints and tendons.

The three great advantages of lasers are their potency, their speed of action, and the ability to focus on an extremely small area. For these reasons they are widely used, and have allowed great advances to be made in microsurgery, and particularly in FIBREOPTIC ENDOSCOPY.... laser

A misnomer applied to the brown MACULES often seen on the backs of the hands of those chronically exposed to sunlight (see LENTIGO). They have no connection with any liver disorder.... liver spots

Diseases of the SKIN for which sunlight is partially or wholly responsible. In su?cient dosage, short-wave ultraviolet light (UVB – see ULTRAVIOLET RAYS (UVR)) always causes ERYTHEMA. Higher doses progressively cause OEDEMA and blistering; this is acute sunburn. Graduated exposure to UVB causes pigmentation (tanning). Prolonged chronic exposure to sunlight eventually accelerates ageing of the exposed skin with LENTIGO formation and loss of COLLAGEN and elastic tissue. After decades of such exposure, epidermal DYSPLASIA and CANCER may supervene.

Drugs given orally or topically may induce phototoxic reactions of various types. Thus, TETRACYCLINES exaggerate sunburn reactions. and the diuretic FRUSEMIDE may cause blistering reactions. Psoralens induce erythema and pigmentation. AMIODARONE also induces pigmentation. (See also PHOTOCHEMOTHERAPY.)

Phytophotodermatitis is a streaky, blistering photodermatosis typically seen on the limbs of children playing in grassy meadows in summer. The phototoxic reaction is caused by psoralens in weeds.

Berlocque dermatitis is a pattern of streaky pigmentation usually seen on women’s necks, caused by a reaction to psoralens in perfumes.

Certain rare metabolic diseases may lead to photosensitisation. They include the PORPHYRIAS and PELLAGRA. Other skin diseases such as lupus erythematosus (see under LUPUS) and ROSACEA may be aggravated by light exposure. Sometimes, in the absence of any of these factors, some people spontaneously develop a sensitivity to light causing various patterns of DERMATITIS or URTICARIA. The most common pattern is ‘polymorphic light eruption’ which typically appears within a day or two of arrival at a sunny holiday destination and persists until departure. Continuously exposed areas, such as the hands and face, may be ‘hardened’ and unaffected.

Treatment Appropriate clothing and headgear, sunscreen creams and lotions are the main preventative measures.... photodermatoses

n. a small brown spot on the skin commonly found on exposed areas of red-haired or blond people. Freckles, which are harmless, appear where there is excessive production of the pigment melanin without any increase in numbers of melanocytes after exposure to sunlight. Compare lentigo.... freckle

A type of skin blemish of which there are 2 main groups: pigmented naevi are caused by abnormality or overactivity of melanocytes (skin cells that produce the pigment melanin); vascular naevi are caused by an abnormal collection of blood vessels.

The most common types of pigmented naevi are freckles, lentigos, and café au lait spots: flat brown areas that may occur where the skin is exposed to the sun. Another common type is a mole, sometimes called a melanocytic naevus. In rare cases, moles become cancerous (see melanoma, malignant). Juvenile melanomas (see melanoma, juvenile) are red-brown naevi that occur in childhood. Blue naevi are common in young girls. Most black and Asian infants are born with blue-black spots on their lower backs (see Mongolian blue spot).

Port-wine stains and strawberry marks (see haemangioma and spider naevi) are examples of vascular naevi.

Most naevi are harmless. However, if a naevus suddenly appears, grows, bleeds, or changes colour, medical advice should be sought immediately to exclude the possibility of skin cancer.... naevus