Elevated blood fats, either from heredity, having so many calories in the diet that they are ending up as a constant stream of liver-synthesized storage fats, an excessively anabolic metabolism...and a constellation of less common disease causes
Garlic (Allium sativum).Plant Part Used: Bulb.Dominican Medicinal Uses: The bulb is traditionally ingested raw for high blood pressure, upper-respiratory infection, common cold, flu-like symptoms and cough, and the alcohol extract is taken internally for sinusitis. The bulb skins are traditionally prepared as a tea and taken internally for indigestion and gastro-intestinal complaints.Safety: The bulb is generally regarded as safe for human consumption. Reported adverse effects include skin burns due to topical application (especially in children with prolonged exposure). Adverse effects associated with internal use include halitosis, body odor, gastrointestinal irritation, constipation, headache, nausea, fatigue and vertigo.Contraindications: Not to be taken at therapeutic doses for 10 days prior to surgery due to antiplatelet activity and risk of excessive bleeding. The bulb is contraindicated during lactation.Drug Interactions: Chlorzoxazone: garlic may reduce drug metabolism. Indomethacin and NSAIDs: risk of excessive bleeding. Protease inhibitors: reduced blood levels. Drugs metabolized by cytochrome P450 2E1: garlic may inhibit efficacy. Forskilin: garlic may potentiate antiplatelet activity.Clinical Data: The following effects have been investigated in human clinical trials: treatment of atherosclerosis, common cold, coronary artery disease, hyperlipidemia, hypertension and unstable angina pectoris.Laboratory & Preclinical Data: The following biological activities have been investigated in laboratory and preclinical studies (in vitro or animal models): antibacterial, anticarcinogenic, antifungal, antihypertensive, antineoplastic, antinociceptive, antioxidant, anti-platelet-aggregant, antithrombic, antiviral and immune enhancing.... ajo
Hook. ex Stocks
Synonym: Commiphora mukul (Hook. ex Stocks) Engl. C. wightii (Arn.) Bhandari.
Family: Burseraceae.
Habitat: Rajasthan, Madhya Pradesh, Assam, Andhra Pradesh, Karnataka.
English: Indian Bdellium, Gum Guggul.
Ayurvedic: Guggul, Devadhoop, Kaushika, Pur, Mahishaaksha, Palankash, Kumbha, Uluukhala.
Unani: Muqallal yahood, Muql, Bu-e-Jahudaan
Siddha/Tamil: Erumaikan Kungiliyam.
Action: Oleo-gum-resin—used for reducing obesity and in rheumatoid arthritis, osteoarthritis, sciatica.
Key application: In the treatment of hyperlipidemia, hypercholestero- laemia and obesity. (WHO.)Guggulipid is hypocholesteremic. Guggul resin contains steroids—gug- glsterones Z and E, guggulsterols IV, diterpenoids; volatile oil, including other constituents, contains a terpene hydrocarbon cembrene A. E- and Z- guggulsterones are characteristic constituents, which distinguish C. mukul from other Commiphore sp.Guggul resin increases catechola- mine biosynthesis and activity in cholesterol-fed rabbits, inhibits platelet aggregation, exhibits anti-inflammatory activity and appears to activate the thyroid gland in rats and chicken. Z- guggulsterone may increase uptake of iodine by thyroid gland and increase oxygen uptake in liver and bicep tissues. (Planta Med 1984,1, 78-80.)The gum is also used in hemiplegia and atherosclerotic disorders; as a gargle in pyrrhoea aveolaris, chronic tonsilitis and pharyngitis. Fumes are recommended in hay fever, chronic bronchitis and nasal catarrh.Oleo-gum resin of Balsamodendron caudatum is also equated with Guggul in Siddha medicine.
Dosage: Oleo-gum-resin—2-4 g (API Vol. I.) 500 mg to 1 g (CCRAS.)... balsamodendron mukul
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