(hexa-) combining form denoting six.
Habitat: Southern India, largely grown in gardens.
Ayurvedic: Panasagandhi, (Harit) Champaka.Siddha/Tamil: Manoranjidam.Folk: Haraa champaa (north), Kathari champaa; Hirvaa champaa (Maharashtra).Action: Cardiac stimulant, uterine stimulant, muscle relaxant.
The extract of the pericarp showed a positive ionotropic and chronotropic effect on all types of experimental animals. The cardiac stimulant and uterine stimulant activity is attributed to the glycosides, whereas the relaxant action on plain muscles and hypotensive effect, which could be partly choliner- gic and partly resulting from vasodila- tory action, are probably due to the presence of the volatile oil.The leaves are found to contain an antifertility principle. The root contains an antimalarial agent.... artabotrys hexapetalusHabitat: Inner ranges of the Himalayas, from Kashmir to Sikkim at 1,800-4,000 m.
English: Indian Podophyllum.Ayurvedic: Giriparpata.Folk: Bana-kakari (Punjab), Venivel (Gujarat), Patvel (Maharashtra). Paapraa, Paapri.Action: Rhizomes and roots— antineoplastic. Strongly irritant to skin and mucous membranes. Used topically as an ointment for venereal warts, verrucae and similar conditions.
Key application: P. peltatum— externally, for removal of pointed condyloma (skin adjacent to the treated area should be protected). (German Commission E.) P hexandrum: Podophyllin (10-40%) for external application, 2-6 h weekly, for anogenital warts. (Indian Herbal Pharmacopoeia.) (Podophyllin is a mitotic poison.)May Apple of North America is equated with Podophyllum peltatum Linn. The main lignin is podophyllo- toxin. Podophyllum hexandrum contains similar lignans with the exception of alpha-and beta-peltatins, which are reportedly absent; the concentration of podophyllotoxin is up to 4.3%. P. peltatum contains about 0.25% and the Taiwanese species P. pleianthum 0.1% podophyllotoxin.(Podophyllotoxin is a valuable lig- nin, as it is used for the synthesis of chemically administered cytostat- ic etoposide and tenoposide.)... podophyllum hexandrum