Glutamate Dehydrogenase: From 1 Different Sources
(glutamic acid dehydrogenase) an important enzyme involved in the *deamination of amino acids.
An ENZYME that performs an essential function in the metabolism of CARBOHYDRATE. A de?ciency in this enzyme – acronym G6PD – results in the breakdown of ERYTHROCYTES (HAEMOLYSIS), usually in the presence of oxidants (see OXIDANT) such as infections or drugs. The de?ciency disorder is a hereditary condition in which the enzyme is absent. The condition, characterised by pallor, rigors and pain in the loin, is divided into African, European (including FAVISM) and Oriental types. Sufferers should avoid substances that trigger haemolysis. Acute episodes are best treated symptomatically.... glucose-6-phosphate dehydrogenase
A deficiency in the enzyme G6PD resulting in a haemolytic anaemia. This haemoglobinopathy contraindicates the use of the 4-aminoquinolines such as primaquine for the radical treatment of benign tertian and ovale tertian malaria.... glucose-6-phosphate-dehydrogenase (g6pd) deficiency
An amino acid (see AMINO ACIDS) which, along with aspartate, is a major excitatory chemical neurotransmitter – method of communication between neurones (see NEURON(E)) – in the central nervous system. The two amino acids are found in the cortex and cerebellum of the BRAIN and in the SPINAL CORD.... glutamate
A food additive that is used as a flavour enhancer and seasoning. Monosodium glutamate (MSG) is the sodium salt of an amino acid. A short-lived illness involving pain in the neck and chest, palpitations, feeling hot, and a headache may occur in some people after eating food to which large amounts of MSG have been added.... monosodium glutamate
n. see oxidoreductase.... dehydrogenase
a hereditary disorder – an X-linked condition (see sex-linked) – in which the absence of the enzyme glucose-6-phosphate dehydrogenase (G6PD), which functions in carbohydrate metabolism, results in the breakdown of the red blood cells (*haemolysis), usually after exposure to *oxidants, such as drugs, or infections. The breakdown causes acute attacks that are characterized by pallor, loin pain, and rigors. There are several varieties of G6PD deficiency, which is most common in people of African, Middle Eastern, and Mediterranean descent. Treatment involves identifying and avoiding agents that trigger the haemolysis and treating acute attacks symptomatically. See also favism.... glucose-6-phosphate dehydrogenase deficiency
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