Ephedrine Health Dictionary

A substance that mimics at least part of adrenalin or catecholamine responses. The term is a little biased towards the minority of sympathetic functions that are adrenergic. A better name might be adrenalomimetic, epinephromimetic, catecholamimetic...or speedomimetic. Examples: coffee, ephedrine, amphetamines.... sympathomimetic

Nutritional Profile Energy value (calories per serving): Low Protein: Trace Fat: Trace Saturated fat: None Cholesterol: None Carbohydrates: Trace Fiber: Trace Sodium: Low Major vitamin contribution: None Major mineral contribution: None

About the Nutrients in This Food Coffee beans are roasted seeds from the fruit of the evergreen coffee tree. Like other nuts and seeds, they are high in proteins (11 percent), sucrose and other sugars (8 percent), oils (10 to 15 percent), assorted organic acids (6 percent), B vitamins, iron, and the central nervous system stimulant caffeine (1 to 2 percent). With the exceptions of caffeine, none of these nutrients is found in coffee. Like spinach, rhubarb, and tea, coffee contains oxalic acid (which binds calcium ions into insoluble compounds your body cannot absorb), but this is of no nutritional consequence as long as your diet contains adequate amounts of calcium-rich foods. Coffee’s best known constituent is the methylxanthine central ner- vous system stimulant caffeine. How much caffeine you get in a cup of coffee depends on how the coffee was processed and brewed. Caffeine is Caffeine Content/Coffee Servings Brewed coffee 60 mg/five-ounce cup Brewed/decaffeinated 5 mg/five-ounce cup Espresso  64 mg/one-ounce serving Instant  47 mg/rounded teaspoon

The Most Nutritious Way to Serve This Food In moderation, with high-calcium foods. Like spinach, rhubarb, and tea, coffee has oxalic acid, which binds calcium into insoluble compounds. This will have no important effect as long as you keep your consumption moderate (two to four cups of coffee a day) and your calcium consumption high.

Diets That May Restrict or Exclude This Food Bland diet Gout diet Diet for people with heart disease (regular coffee)

Buying This Food Look for: Ground coffee and coffee beans in tightly sealed, air- and moisture-proof containers. Avoid: Bulk coffees or coffee beans stored in open bins. When coffee is exposed to air, the volatile molecules that give it its distinctive flavor and richness escape, leaving the coffee flavorless and/or bitter.

Storing This Food Store unopened vacuum-packed cans of ground coffee or coffee beans in a cool, dark cabinet—where they will stay fresh for six months to a year. They will lose some flavor in storage, though, because it is impossible to can coffee without trapping some flavor- destroying air inside the can. Once the can or paper sack has been opened, the coffee or beans should be sealed as tight as possible and stored in the refrigerator. Tightly wrapped, refrigerated ground coffee will hold its freshness and flavor for about a week, whole beans for about three weeks. For longer storage, freeze the coffee or beans in an air- and moistureproof container. ( You can brew coffee directly from frozen ground coffee and you can grind frozen beans without thawing them.)

Preparing This Food If you make your coffee with tap water, let the water run for a while to add oxygen. Soft water makes “cleaner”-tasting coffee than mineral-rich hard water. Coffee made with chlorinated water will taste better if you refrigerate the water overnight in a glass (not plastic) bottle so that the chlorine evaporates. Never make coffee with hot tap water or water that has been boiled. Both lack oxygen, which means that your coffee will taste flat. Always brew coffee in a scrupulously clean pot. Each time you make coffee, oils are left on the inside of the pot. If you don’t scrub them off, they will turn rancid and the next pot of coffee you brew will taste bitter. To clean a coffee pot, wash it with detergent, rinse it with water in which you have dissolved a few teaspoons of baking soda, then rinse one more time with boiling water.

What Happens When You Cook This Food In making coffee, your aim is to extract flavorful solids (including coffee oils and sucrose and other sugars) from the ground beans without pulling bitter, astringent tannins along with them. How long you brew the coffee determines how much solid material you extract and how the coffee tastes. The longer the brewing time, the greater the amount of solids extracted. If you brew the coffee long enough to extract more than 30 percent of its solids, you will get bitter compounds along with the flavorful ones. (These will also develop by let- ting coffee sit for a long time after brewing it.) Ordinarily, drip coffee tastes less bitter than percolator coffee because the water in a drip coffeemaker goes through the coffee only once, while the water in the percolator pot is circulated through the coffee several times. To make strong but not bitter coffee, increase the amount of coffee—not the brewing time.

How Other Kinds of Processing Affect This Food Drying. Soluble coffees (freeze-dried, instant) are made by dehydrating concentrated brewed coffee. These coffees are often lower in caffeine than regular ground coffees because caffeine, which dissolves in water, is lost when the coffee is dehydrated. Decaffeinating. Decaffeinated coffee is made with beans from which the caffeine has been extracted, either with an organic solvent (methylene chloride) or with water. How the coffee is decaffeinated has no effect on its taste, but many people prefer water-processed decaf- feinated coffee because it is not a chemically treated food. (Methylene chloride is an animal carcinogen, but the amounts that remain in coffees decaffeinated with methylene chloride are so small that the FDA does not consider them hazardous. The carcinogenic organic sol- vent trichloroethylene [TCE], a chemical that causes liver cancer in laboratory animals, is no longer used to decaffeinate coffee.)

Medical Uses and/or Benefits As a stimulant and mood elevator. Caffeine is a stimulant. It increases alertness and concentra- tion, intensifies muscle responses, quickens heartbeat, and elevates mood. Its effects derive from the fact that its molecular structure is similar to that of adenosine, a natural chemical by-product of normal cell activity. Adenosine is a regular chemical that keeps nerve cell activ- ity within safe limits. When caffeine molecules hook up to sites in the brain when adenosine molecules normally dock, nerve cells continue to fire indiscriminately, producing the jangly feeling sometimes associated with drinking coffee, tea, and other caffeine products. As a rule, it takes five to six hours to metabolize and excrete caffeine from the body. During that time, its effects may vary widely from person to person. Some find its stimu- lation pleasant, even relaxing; others experience restlessness, nervousness, hyperactivity, insomnia, flushing, and upset stomach after as little as one cup a day. It is possible to develop a tolerance for caffeine, so people who drink coffee every day are likely to find it less imme- diately stimulating than those who drink it only once in a while. Changes in blood vessels. Caffeine’s effects on blood vessels depend on site: It dilates coronary and gastrointestinal vessels but constricts blood vessels in your head and may relieve headache, such as migraine, which symptoms include swollen cranial blood vessels. It may also increase pain-free exercise time in patients with angina. However, because it speeds up heartbeat, doc- tors often advise patients with heart disease to avoid caffeinated beverages entirely. As a diuretic. Caffeine is a mild diuretic sometimes included in over-the-counter remedies for premenstrual tension or menstrual discomfort.

Adverse Effects Associated with This Food Stimulation of acid secretion in the stomach. Both regular and decaffeinated coffees increase the secretion of stomach acid, which suggests that the culprit is the oil in coffee, not its caffeine. Elevated blood levels of cholesterol and homocysteine. In the mid-1990s, several studies in the Netherlands and Norway suggested that drinking even moderate amounts of coffee (five cups a day or less) might raise blood levels of cholesterol and homocysteine (by-product of protein metabolism considered an independent risk factor for heart disease), thus increas- ing the risk of cardiovascular disease. Follow-up studies, however, showed the risk limited to drinking unfiltered coffees such as coffee made in a coffee press, or boiled coffees such as Greek, Turkish, or espresso coffee. The unfiltered coffees contain problematic amounts of cafestol and kahweol, two members of a chemical family called diterpenes, which are believed to affect cholesterol and homocysteine levels. Diterpenes are removed by filtering coffee, as in a drip-brew pot. Possible increased risk of miscarriage. Two studies released in 2008 arrived at different conclusions regarding a link between coffee consumption and an increased risk of miscar- riage. The first, at Kaiser Permanente (California), found a higher risk of miscarriage among women consuming even two eight-ounce cups of coffee a day. The second, at Mt. Sinai School of Medicine (New York), found no such link. However, although the authors of the Kaiser Permanente study described it as a “prospective study” (a study in which the research- ers report results that occur after the study begins), in fact nearly two-thirds of the women who suffered a miscarriage miscarried before the study began, thus confusing the results. Increased risk of heartburn /acid reflux. The natural oils in both regular and decaffeinated coffees loosen the lower esophageal sphincter (LES), a muscular valve between the esopha- gus and the stomach. When food is swallowed, the valve opens to let food into the stomach, then closes tightly to keep acidic stomach contents from refluxing (flowing backwards) into the esophagus. If the LES does not close efficiently, the stomach contents reflux and cause heartburn, a burning sensation. Repeated reflux is a risk factor for esophageal cancer. Masking of sleep disorders. Sleep deprivation is a serious problem associated not only with automobile accidents but also with health conditions such as depression and high blood pres- sure. People who rely on the caffeine in a morning cup of coffee to compensate for lack of sleep may put themselves at risk for these disorders. Withdrawal symptoms. Caffeine is a drug for which you develop a tolerance; the more often you use it, the more likely you are to require a larger dose to produce the same effects and the more likely you are to experience withdrawal symptoms (headache, irritation) if you stop using it. The symptoms of coffee-withdrawal can be relieved immediately by drinking a cup of coffee.

Food/Drug Interactions Drugs that make it harder to metabolize caffeine. Some medical drugs slow the body’s metabolism of caffeine, thus increasing its stimulating effect. The list of such drugs includes cimetidine (Tagamet), disulfiram (Antabuse), estrogens, fluoroquinolone antibiotics (e.g., ciprofloxacin, enoxacin, norfloxacin), fluconazole (Diflucan), fluvoxamine (Luvox), mexi- letine (Mexitil), riluzole (R ilutek), terbinafine (Lamisil), and verapamil (Calan). If you are taking one of these medicines, check with your doctor regarding your consumption of caf- feinated beverages. Drugs whose adverse effects increase due to consumption of large amounts of caffeine. This list includes such drugs as metaproterenol (Alupent), clozapine (Clozaril), ephedrine, epinephrine, monoamine oxidase inhibitors, phenylpropanolamine, and theophylline. In addition, suddenly decreasing your caffeine intake may increase blood levels of lithium, a drug used to control mood swings. If you are taking one of these medicines, check with your doctor regarding your consumption of caffeinated beverages. Allopurinol. Coffee and other beverages containing methylxanthine stimulants (caffeine, theophylline, and theobromine) reduce the effectiveness of the antigout drug allopurinol, which is designed to inhibit xanthines. Analgesics. Caffeine strengthens over-the-counter painkillers (acetaminophen, aspirin, and other nonsteroidal anti-inflammatories [NSAIDS] such as ibuprofen and naproxen). But it also makes it more likely that NSAIDS will irritate your stomach lining. Antibiotics. Coffee increases stomach acidity, which reduces the rate at which ampicillin, erythromycin, griseofulvin, penicillin, and tetracyclines are absorbed when they are taken by mouth. (There is no effect when the drugs are administered by injection.) Antiulcer medication. Coffee increases stomach acidity and reduces the effectiveness of nor- mal doses of cimetidine and other antiulcer medication. False-positive test for pheochromocytoma. Pheochromocytoma, a tumor of the adrenal glands, secretes adrenalin, which is converted to VM A (vanillylmandelic acid) by the body and excreted in the urine. Until recently, the test for this tumor measured the levels of VM A in the patient’s urine and coffee, which contains VM A, was eliminated from patients’ diets lest it elevate the level of VM A in the urine, producing a false-positive test result. Today, more finely drawn tests make this unnecessary. Iron supplements. Caffeine binds with iron to form insoluble compounds your body cannot absorb. Ideally, iron supplements and coffee should be taken at least two hours apart. Birth control pills. Using oral contraceptives appears to double the time it takes to eliminate caffeine from the body. Instead of five to six hours, the stimulation of one cup of coffee may last as long as 12 hours. Monoamine oxidase (MAO) inhibitors. Monoamine oxidase inhibitors are drugs used to treat depression. They inactivate naturally occurring enzymes in your body that metabolize tyra- mine, a substance found in many fermented or aged foods. Tyramine constricts blood vessels and increases blood pressure. Caffeine is a substance similar to tyramine. If you consume excessive amounts of a caffeinated beverage such as coffee while you are taking an M AO inhibitor, the result may be a hypertensive crisis. Nonprescription drugs containing caffeine. The caffeine in coffee may add to the stimulant effects of the caffeine in over-the-counter cold remedies, diuretics, pain relievers, stimulants, and weight-control products containing caffeine. Some cold pills contain 30 mg caffeine, some pain relievers 130 mg, and some weight-control products as much as 280 mg caffeine. There are 110 –150 mg caffeine in a five-ounce cup of drip-brewed coffee. Sedatives. The caffeine in coffee may counteract the drowsiness caused by sedative drugs; this may be a boon to people who get sleepy when they take antihistamines. Coffee will not, however, “sober up” people who are experiencing the inebriating effects of alcoholic beverages. Theophylline. Caffeine relaxes the smooth muscle of the bronchi and may intensif y the effects (and/or increase the risk of side effects) of this antiasthmatic drug.... coffee

Wall. ex Stapf.

Family: Ephedraceae.

Habitat: The drier regions of the temperate and alpine Himalayas from Kashmir to Sikkim from 2,350 to 5,350 m.

English: Ephedra (Ephedra sinica Stapf.)

Ayurvedic: Soma, Soma-valli (substitute).

Folk: Asmaaniyaa, Budaagur (Punjab); Tipat, Traani (Himalayan region).

Action: Circulatory stimulant, bron- chodilator, vasodilator, antiallergic, antiasthmatic (usualy given with expectorants), diaphoretic. Not prescribed with antidepressants.

Key application: Ephedra sinica— in diseases of the respiratory tract and mild bronchospasms. Also in acute coryza, allergic rhinitis and sinusitis. (German Commission E.) In the treatment of nasal congestion due to hay fever, allergic rhinitis, acute coryza, cold, sinusitis and as abronchodilator. (WHO.)

Contraindicated in anxiety, restlessness, high blood pressure, glucoma, impaired circulation of the cerebrum, adenoma of prostate with residual urine accumulation, pheochromocy- toma, thyrotoxicosis. (German Commission E.)

Ephedra is official in the national pharmacopoeias of China, Japan and Germany. The herb is listed in Ayurvedic Pharmacopoeia. Only its isolated derivatives, ephedrine and ephedrine hydrochloride are official in Indian Pharmacopoeia.

Ephedrine is toxic at more than 300 mg in 1 day (Francis Brinker.)

Aerial parts yielded ephedrine and ephedroxane. Pseudoephedrine is the most active anti-inflammatory principle of Ephedra sp., it exhibited inhibitory action on a number of acute inflammations. Ephedroxane possesses a minor anti-inflammatory principle. Among the Indian species, Ephedra major, found in Lahul, contains over 2.56% alkaloids of which nearly three fourths is ephidrine. Ephedra gerardiana contains 1.22% total alkaloids and 0.68% ephedrine.

On 30 December 2003, the FDA banned ephedra products in the US.... ephedra gerardiana

With a reputation of an energy tea, Ephedra tea was taken by athletes and it is the subject of many controversies. Learn more about other benefits of this kind of tea. About Ephedra tea Ephedra, also known as Ma huang in Chinese, has been used in Chinese traditional medicine for centuries to treat cold related conditions. Botanically called Ephedra sinica, this is an evergreen shrub native to Asia. The plant’s leaves and stems are harvested, dried and then sold as teas, tinctures, extracts or tablets. The stems of ephedra have pungent and bitter taste and also diaphoretic, diuretic, pectoral, vasoconstrictive and vasodilative properties. The main chemical constituents in ephedra are ephedrine and pseudoephedrine which work by stimulating the nervous system, dilating bronchial tubes, elevating blood pressure, and increasing heart rate. Due to these effects, ephedra became a favorite for athletes as it is believed that the herb enhances athletic performance. Several incidences of adverse effects and even death that may have been caused by excessive consumption of ephedra and ephedra supplements led the Food and Drug Administration (FDA) to ban the sale of ephedra supplements in the United States in 2004. Currently, ephedra is still a subject of debate, especially when it comes to athletes in international competitions and anti-doping testes. However, don’t avoid Ephedra tea as it has important benefits as well. Ephedra tea preparation Ephedra tea can be made by placing about 10 grams of ephedra herb in 2 cups of water and let it boil for 10 minutes. Filter out the herbs before drinking the Ephedra tea. Ephedra tea benefits Here are several health benefits attributed to Ephedra tea. Ephedra Tea may alleviate respiratory ailments such asthma, colds, coughs and hay fever, as well as various allergic symptoms. Ephedra Tea may help expel exterior pathogens and regulate the proper functioning of the lungs. Ephedra Tea, taken in a regulated and supervised manner, may be effective for short-term weight loss, often associated with caffeine. Taken in a regulated and supervised manner, it stimulates the central nervous system may help boost energy and enhance alertness. Ephedra tea side effects Excessive use of Ephedra tea can cause dizziness, irregular heartbeat, seizures, strokes and even death. This tea is not recommended during pregnancy, breastfeeding and to persons with high blood pressure or heart disease. Ephedra tea should not be used as an energy booster, sports or diet aid or in combination with any stimulant such as caffeine as it may lead to unwanted side effects. In spite of these side effects, you can occasionally drink a cup of Ephedra tea, but first ask your current practitioner and pay attention to overdose.... ephedra tea - the energy tea

These drugs temporarily raise the BLOOD PRESSURE by constricting peripheral blood vessels. Sometimes they are used as a speedy way of raising blood pressure when other treatment has failed. EPHEDRINE and methoxamine hydrochloride are examples of this type of sympathomimetic.

Cardiopulmonary resuscitation ADRENALINE (epinephrine) is given intravenously in cardiac arrest, and other drugs used include ATROPINE and CALCIUM.... vasoconstrictor sympathomimetics

Vasoconstrictor sympathomimetic drugs, such as EPHEDRINE and NORADRENALINE, raise the BLOOD PRESSURE temporarily by acting on receptors that constrict peripheral blood vessels. They are occasionally used as a quick way of raising blood pressure when other measures have failed, but they have potentially serious side-effects on the kidney. Vasoconstrictors are also used with local anaesthetics (see under ANAESTHESIA) to counteract the latter’s vasodilator e?ect. Adrenaline will reduce local blood ?ow, slow the absorption of anaesthetic and prolong its e?ect.... vasoconstrictors

The nose and nasal sinuses (see SINUS) produce up to a litre of MUCUS in 24 hours, most of which enters the stomach via the NASOPHARYNX. Changes in the nasal lining mucosa occur in response to changes in humidity and atmospheric temperature; these may cause severe congestion, as might an allergic reaction or nasal polyp.

Treatment Topical nasal decongestants include sodium chloride drops and corticosteroid nasal drops (for polyps). For commoncold-induced congestion, vapour inhalants, decongestant sprays and nasal drops, including EPHEDRINE drops, are helpful. Overuse of decongestants, however, can produce a rebound congestion, requiring more treatment and further congestion, a tiresome vicious circle. Allergic RHINITIS (in?ammation of the nasal mucosa) usually responds to ipratropium bromide spray.

Systemic nasal decongestants given by mouth are not always as e?ective as topical administrations but they do not cause rebound congestion. Pseudoephedrine hydrochoride is available over the counter, and most common-cold medicines contain anticongestant substances.... nasal congestion

Pu’erh tea is a type of post-fermented tea produced in China. Read this article to find out more about its many health benefits! About Pu’erh Tea Pu’erh tea is a post-fermented tea produced in the Chinese province Yunnan. Post-fermented teas are different from other types of tea in the sense that, after the leaves are dried and rolled, they undergo a microbial fermentation process. The pu’erh teais available as loose leaves or as tea brick (tea leaves packed in molds and pressed into block form). There are also two categories of pu’erh tea: the raw type and the ripe type. Raw pu’erh tea can count as a type of green tea. Ripened or aged pu’erh tea is often mistakenly called a type of black tea, though it isn’t. How to prepare Pu’erh Tea Pu’erh tea can be bought and prepared in loose leaf form, in tea bag form, or in compacted cake form. If you’re using leaves, add a teaspoon to a cup of freshly boiled water and let it steep for about 20 seconds before you pour off the water; this process id called rinsing, in order to prepare the leaves for the tea. Next, pour freshly boiled water again, let it steep for 30 seconds or one minute. This will give the tea a mild, but pleasant flavor. If you want a stronger flavor, you can let it steep up to 50 minutes, until it turns as dark as coffee. Pu’erh leaves can be resteeped several times (4-8 times). Just add about 20 more seconds to each steeping process. The same applies to pu’erh tea in compacted cake form. To get the leaves, either flake off pieces of the cake, or steam the entire cake until it becomes soft. Pu’erh Tea Benefits Pu’erh tea had important health benefits related to blood circulation. It can help lower blood cholesterol levels. It also boosts the flow of blood and enhances your blood circulation. Drinking pu’erh tea can help prevent cancer, as it helps prevent the formation and growth of cancer cells. It also promotes a proper, healthy digestion, and is good for your spleen. You don’t have to worry even if you’re on a diet; drinking pu’erh tea will help you lose weight, as it breaks down and reduces the fat in your body. As pu’erh tea contains caffeine, drinking it helps keep you alert and focused. It also helps with removing toxins from your body, and it can prove to be useful if you’re dealing with various aches and pains. Pu’erh tea can also help you if you’ve got a hangover, especially if you get a headache. Also, it can act as a substitute for coffee, and can have a relaxing effect on you. Pu’erh Tea Side Effects Because of its caffeine content, pu’erh tea shouldn’t be consumed by pregnant or breastfeeding women, as it can affect the baby. Also, you shouldn’t drink pu’erh tea if you’ve got anxiety, bleeding disorders, heart problems, diabetes, irritable bowel syndrome, glaucoma, high blood pressure or osteoporosis. It can affect your condition in all of these cases. Pu’erh tea can also interact with medications. A few examples include amphetamines, cimetidine, ephedrine, adenosine, or medications for depression, asthma and slow blood clotting. The list includes more, so if you’re under medication, make sure you check with your doctor first, to see if it’s safe to drink pu’erh tea.   Pu’erh tea has important health benefits, though the same goes for side effects, as well. Make sure it’s safe to drink pu’erh tea, and then you can enjoy a cup of tea without having to worry about its side effects.... pu’erh tea pros and cons

Burm. f.

Synonym: S. carpinifolia auct. non Linn f.

Family: Malvaceae.

Habitat: Throughout the warmer parts of India.

English: Hornbeam-Leaved Sida.

Ayurvedic: Balaa (white-flowered var.).

Folk: Jangali Methi.

Action: Root—astringent, cooling, stomachic, febrifuge, diuretic; used for nervous and sexual debility, haemorrhoids, biliary disorders. Leaves—demulcent; applied to testicular swellings and elephantiasis.

The root contains alkaloids—phen- ethylamine, ephedrine (major), si- ephedrine, vasicinol, vasicinone, va- sicine, choline, hypaphorine and betaine. (These alkaloids are also present in aerial parts.) The root also contains alpha-amyrin and an hormone, ecdys- terone. Whole plant, as well as the root, contains an alkaloid cryptolepine. Cryptolepine exhibits hypotensive and antimicrobial activity.

The seeds contain 0.26% of the alkaloids and roots 0.066%.

The water-soluble portion of the alcoholic extract of the plant exerts spasmodic action of the smooth muscles of ileum, trachea, uterus and heart of experimental animals. (The activity bears similarity to that of acetylcholine.)... sida acuta

Linn.

Family: Malvaceae.

Habitat: Throughout India in moist places.

English: Country Mallow.

Ayurvedic: Balaa (yellow-flowered var.), Sumanganaa, Khara- yashtikaa, Balini, Bhadrabalaa, Bhadraudani, Vaatyaalikaa.

Unani: Bariyaara, Khirhati, Khireti, Kunayi.

Siddha/Tamil: Nilatutti.

Action: Juice of the plant— invigorating, spermatopoietic, used in spermatorrhoea. Seeds— nervine tonic. Root—(official part in Indian medicine) used for the treatment of rheumatism; neurological disorders (hemiplegia, facial paralysis, sciatica); polyuria, dysuria, cystitis, strangury and hematuria; leucorrhoea and other uterine disorders; fevers and general debility. Leaves—demulcent, febrifuge; used in dysentery.

Ephedrine and si-ephedrine are the major alkaloids in the aerial parts. The total alkaloid content is reported to be 0.085%, the seeds contain the maximum amount. In addition to alkaloids, the seeds contain a fatty oil (3.23%), steroids, phytosterols, resin, resin acids, mucin and potassium nitrate.

The root contains alkaloids—ephed- rine, si-ephedrine, beta-phenethyl- amine, carboxylated tryptamines and hypaphorine, quinazoline alkaloids— vasicinone, vasicine and vasicinol. Choline and betaine have also been isolated.

A sitoindoside, isolated from the plant, has been reported to exhibit adaptogenic and immunostimulatory activities. Alcoholic extract of the plant possesses antibacterial and antipyretic propeptide. Ethanolic extract of the plant depresses blood pressure in cats and dogs.... sida cordifolia

Linn.

Family: Malvaceae.

Habitat: Throughout India, in moist places.

English: Common Bala.

Ayurvedic: Mahaabalaa, Mahaa- samangaa, Sahadevaa, Kshetrabalaa.

Unani: Bariyaara (red-flowered var.).

Siddha/Tamil: Athi Bala-chedi, Chitrmutti, Tennacham.

Action: Plant—used as a supporting drug in pulmonary tuberculosis, nervous diseases and rheumatism. Leaves—applied to swelling as paste. Stem-mucilage—demulcent and emollient. Used internally in skin diseases and as a diuretic and febrifuge.

The Ayurvedic Pharmacopoeia of India recommends the root in deficient spermatogensis and oedema.

Alkaloids, ephedrine, si-ephedrine and cryptolepine, are reported from aerial parts. The root contains 0.054% alkaloids, beta-phenethylamine, N- methyl-beta-phenethylamine, vasici- nol, vasicinone, vasicine, choline and betaine. These alkaloids are also present in the aerial parts.

Alcoholic extract of the root exhibited antibacterial and antipyretic activities.

Proteins, linoleic, malvlic and ster- culic acids have been reported from seeds.

Dosage: Root—3-6 g powder. (API, Vol. III.)... sida rhombifolia

Linn.

Synonym: S. alba Linn.

Family: Malvaceae.

Habitat: Throughout the hotter parts of India, ascending to an altitude of 1,350 m.

English: Prickly Sida.

Ayurvedic: Naagabalaa, Balaa- kantakini, Gangaati.

Siddha/Tamil: Arivalmanai-poondu.

Folk: Gulasakari, Gangeti, Jangali- methi.

Action: Root—nervine tonic and diaphoretic; used in debility and fevers. Decoction given as a demulcent in irritability of bladder and genitourinary tract. Leaves—demulcent and refrigerant; used for scalding urine.

The root contains alkaloids—beta- phenethylamine, ephedrine, si-ephed- rine, vasicinol, vasicinone, vasicine, choline, hypaphorine, methyl ester, hy- paphorine and betaine. These alkaloids are present in aerial parts as well.

Ethanolic extract of the plant exhibits hypoglycaemic activity. It depressed the normal blood pressure and lowered the activity ofsmooth muscles of the ileum of experimental animals.... sida spinosa

The ?eld of medicine concerned with physical ?tness and the diagnosis and treatment of both acute and chronic sports injuries sustained during training and competition. Acute injuries are extremely common in contact sports, and their initial treatment is similar to that of those sustained in other ways, such as falls and road traf?c incidents. Tears of the muscles (see MUSCLES, DISORDERS OF), CONNECTIVE TISSUE and LIGAMENTS which are partial (sprains) are initially treated with rest, ice, compression, and elevation (RICE) of the affected part. Complete tears (rupture) of ligaments (see diagrams) or muscles, or fractures (see BONE, DISORDERS OF – Bone fractures) require more prolonged immobilisation, often in plaster, or surgical intervention may be considered. The rehabilitation of injured athletes requires special expertise

– an early graded return to activity gives the best long-term results, but doing too much too soon runs the risk of exacerbating the original injury.

Chronic (overuse) injuries affecting the bones (see BONE), tendons (see TENDON) or BURSAE of the JOINTS are common in many sports. Examples include chronic INFLAMMATION of the common extensor tendon where it

attaches to the later EPICONDYLE of the humerus – common in throwers and racquet sportspeople – and stress fractures of the TIBIA or METATARSAL BONES of the foot in runners. After an initial period of rest, management often involves coaching that enables the athlete to perform the repetitive movement in a less injury-susceptible manner.

Exercise physiology is the science of measuring athletic performance and physical ?tness for exercise. This knowledge is applied to devising and supervising training regimens based on scienti?c principles. Physical ?tness depends upon the rate at which the body can deliver oxygen to the muscles, known as the VO2max, which is technically di?cult to measure. The PULSE rate during and after a bout of exercise serves as a good proxy of this measurement.

Regulation of sport Sports medicine’s role is to minimise hazards for participants by, for example, framing rule-changes which forbid collapsing the scrum, which has reduced the risk of neck injury in rugby; and in the detection of the use of drugs taken to enhance athletic performance. Such attempts to gain an edge in competition undermine the sporting ideal and are banned by leading sports regulatory bodies. The Olympic Movement Anti-Doping Code lists prohibited substances and methods that could be used to enhance performance. These include some prohibited in certain circumstances as well as those completely banned. The latter include:

stimulants such as AMPHETAMINES, bromantan, ca?eine, carphedon, COCAINE, EPHEDRINE and certain beta-2 agonists.

NARCOTICS such as DIAMORPHINE (heroin), MORPHINE, METHADONE HYDROCHLORIDE and PETHIDINE HYDROCHLORIDE.

ANABOLIC STEROIDS such as methandione, NANDROLONE, stanazol, TESTOSTERONE, clenbuterol, androstenedone and certain beta-2 agonists.

peptide HORMONES, mimetics and analogues such as GROWTH HORMONE, CORTICOTROPHIN, CHORIONIC GONADOTROPHIC HORMONE, pituitary and synthetic GONADOTROPHINS, ERYTHROPOIETIN and INSULIN. (The list produced above is not comprehen

sive: full details are available from the governing bodies of relevant sports.) Among banned methods are blood doping (pre-competition administration of an athlete’s own previously provided and stored blood), administration of arti?cial oxygen carriers or plasma expanders. Also forbidden is any pharmacological, chemical or physical manipulation to affect the results of authorised testing.

Drug use can be detected by analysis of the URINE, but testing only at the time of competition is unlikely to detect drug use designed to enhance early-season training; hence random testing of competitive athletes is also used.

The increasing professionalism and competitiveness (among amateurs and juveniles as well as professionals) in sports sometimes results in pressures on participants to get ?t quickly after injury or illness. This can lead to

players returning to their activity before they are properly ?t – sometimes by using physical or pharmaceutical aids. This practice can adversely affect their long-term physical capabilities and perhaps their general health.... sports medicine

A medical curiosity occurring in some neurotic people who lose consciousness followed by muscular rigidity. Although rare, it may follow excessive stress. Suspension of heart beat, breathing. Other vital functions simulate death and are a cause for alarm. Rigidity may cause the body to assume a statue-like appearance. The subject should be carefully watched.

Treatment. Antispasmodics.

As swallowing is not possible, the gums should be rubbed with a little dilute Tincture or Liquid

Extract Lobelia, Eucalyptus, Thyme, Valerian or Wild Lettuce. When swallowing is possible, a cup of Chamomile, Lime blossom or Ephedra tea assists.

Practitioner: Ephedrine, 8-60mg by mouth, thrice daily. ... catalepsy

Ephedra sinica stapf., Ephedra equisentina Bunge and Ephedra gerardiana Wall (including Ephedra nebrodensis Tineo). Twigs. German: Meertra?ubchen. French: Ephe?dre. Italian: Uva di mare. Iranian: Huma. Japanese: Ma oh. Indian: Butshur. Chinese: Ma Huang.

Constituents: Alkaloids – ephedrine, pseudoephedrine.

Action: brain, heart and circulatory stimulant, antasthmatic, bronchodilator, anti-allergic, vasodilator, hypertensive, diaphoretic. Dilates vessels of the heart causing a rise in blood pressure. Cough sedative. Febrifuge, antispasmodic. The essential oil has antibacterial and antiviral properties.

Uses: Practitioner’s first choice for asthma. Bronchitis, breathlessness, whooping cough. Used for such chest conditions for over a millennia in Chinese medicine.

Allergies: hay fever, irritative skin rashes. Low blood pressure. Hypothermia. Bed-wetting. Myasthenia gravis BHP (1983). Chinese Barefoot doctors inject the tea into nostrils for hay fever.

Usually given with expectorants: Liquorice, Lobelia, Senega, Sundew. “Combines well with Lobelia and Skunk Cabbage for bronchitis; and with Horsetail for frequency of urine.” (Fletcher Hyde) Contra-indications: hypertension, coronary thrombosis, thyrotoxicosis, glaucoma. Not given with anti- depressants (MAO inhibitors).

Preparations: Thrice daily. Average dose: 15-60mg.

Tea. Quarter to half a teaspoon herb to cup water simmered gently 5 minutes. Half a cup. Liquid extract. BHP (1983) 1:1 in 45 per cent alcohol. Dose: 15-45 drops (1-3ml). Tincture BHP (1983) 1 part to 4 parts 45 per cent alcohol. Dose: 6-8ml.

Ephedrine. Maximum dose: 30mg. Maximum daily dose 60mg.

Store in airtight container out of the light. Pharmacy only medicine. Practitioners only. ... ephedra

Autoimmune disorder. Nerve weakness due to defective nerve impulse transmission. Rare. Neuro-muscular disease with spells of extreme weakness. Sight, voice and breathing are most at risk. Often misdiagnosed as neurosis. Muscles fail to respond to directions from the brain. May be associated with a tumour of the thymus, removal of which is curative.

Symptoms: weakened eye muscles producing drooping eyelids (ptosis). Double vision (diplopia). Weakness of neck muscles served by the cranial nerves. Thymus gland abnormality. Difficult swallowing, chewing, slurred speech, fatigue, ‘simply cannot hold her head up’.

Lid-lag test and Tensilon tests establish diagnosis.

Treatment should give support to the thymus gland.

Alternatives. To improve nerve transmission: but not cure. Ephedra tea BHP (1983). 1 teaspoon to each cup boiling water; infuse 15 minutes, thrice daily.

Formula. Oats 2; Ginseng 1; Sarsaparilla 1; pinch Cayenne or drops Tincture Capsicum. Dose: Liquid Extracts: 1 teaspoon. Tinctures: 2 teaspoons. Powders: 500mg (two 00 capsules or one-third teaspoon). Thrice daily.

Practitioner: Ephedrine.

Diet: Gluten-free. ... myasthenia gravis (mg)

Overpowering desire to sleep at any time of the day and in any situation. Psychiatrists believe it to be an escape mechanism, a form of hysteria. Seems to run in families. Official definition favours a neurologic brain disorder rather than a psychogenic disorder which has its origin in the mind. May be mis-diagnosed and treated as schizophrenic with antipsychotic drugs.

Symptoms. Tired and apathetic. Muscle weakness. May hear voices and have terrifying hallucinations. Causes may be emotional, autotoxaemic, psychic disturbance or spirit possession.

Treatment. Central nervous system stimulants, antidepressants.

Alternatives. Ginkgo, Siberian Ginseng, Camphor, Horseradish, Prickly Ash bark, Gotu Kola, Kola. Yerbe mate tea.

Tablets/capsules. Prickly Ash, Thuja, Ginseng, Gotu Kola.

Formula. Ginkgo 2; Prickly Ash 1; Ginseng 1. Doses – Powders: 500mg (two 00 capsules or one-third teaspoon). Liquid Extracts: 1 teaspoon. Tinctures: 2 teaspoons. In water or honey, thrice daily. Practitioner. Ephedra – 1 teaspoon to each cup boiling water; half-1 cup at bedtime. Ephedrine.

Note: Researchers have discovered a “biologic marker for the disease – an antigen called HLA.DR2 found in almost 100 per cent of narcoleptic patients”. The antigen appears in only 25 per cent of the general population. This unusual finding may also be evidence that the immune system is somehow involved in the onset of narcolepsy. (American Family Physician, July 1988) ... narcolepsy

To have effect upon the nasal mucosa, drops for congestion of the upper respiratory tract should be correctly instilled otherwise they may arrive in the stomach. The patient should lie on his back with his head hanging over the edge of the bed. Drops, blood heat, should be instilled into the nostrils and the patient remain in the same position for two minutes. Drops should be used in this way for no more than three days. Ephedrine BPC, Garlic, Lobelia, Menthol, etc.

Effective oil: Tea Tree oil (1 part) to 20 parts Almond, Olive or Corn oil.

Alternative. Adopt Mecca position. Kneel down, place head on ground and tuck under. The spray will reach the maximum surface of action in the nasal cavity. ... nose drops drill

Drugs that are used to relieve nasal congestion commonly in people with upper respiratory tract infections.

They work by narrowing blood vessels in the membranes lining the nose.

This action reduces swelling, inflammation, and the amount of mucus produced by the lining.

Common drugs include ephedrine, oxymetazoline, and phenylephrine.

Small amounts of these drugs are present in many over-thecounter cold remedies.

Taken by mouth, decongestant drugs may cause tremor and palpitations.

Adverse effects are unlikely with nose drops, but if taken for several days they become ineffective and symptoms may then recur or worsen despite continued treatment.... decongestant drugs

(MAOI) a drug that prevents the activity of the enzyme *monoamine oxidase (MAO). MAO inhibitors include phenelzine, isocarboxazid, and tranylcypromine. These drugs are irreversible inhibitors of monoamine oxidase A, whose use as antidepressants is now restricted because of the severity of their side-effects. These include interactions with other drugs (e.g. ephedrine, phenylephrine) and with foods or drinks containing *tyramine (e.g. cheese or red wine) to produce a sudden and dangerous increase in blood pressure. *Moclobemide is a reversible inhibitor of monoamine oxidase A (RIMA), with less severe side-effects. See also selegiline.... mao inhibitor

n. an agent that causes narrowing of the blood vessels and therefore a decrease in blood flow. Vasoconstrictor drugs are alpha agonists (see sympathomimetic): they are used to raise the blood pressure in disorders of the circulation, shock, or severe bleeding and to maintain blood pressure during surgery (e.g. *ephedrine, *metaraminol, *phenylephrine). Some vasoconstrictors (e.g. ephedrine, *xylometazoline) have a rapid effect when applied to mucous membranes and may be used to relieve nasal congestion. If the blood pressure rises too quickly headache and vomiting may occur. A vasoconstrictor is often added to local anaesthetic solutions used in dentistry to prolong their effectiveness.... vasoconstrictor